SK15096A3 - Therapeutic peptide derivatives and a method of their application - Google Patents

Therapeutic peptide derivatives and a method of their application Download PDF

Info

Publication number: SK15096A3
Authority: SK; Slovakia
Prior art keywords: cys; phe; peptide; thr; lys
Prior art date: 1993-08-09

Application number

SK150-96A

Other languages

English (en)

Slovak (sk)

Inventor

Hyuk Kim Sun

Xin Dong Zheng

John E Taylor

Sylviane Moreau

Susan R Keyes

Original Assignee

Biomeasure Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1993-08-09

Filing date

1994-08-08

Publication date

1996-07-03

1994-08-08 Application filed by Biomeasure Inc filed Critical Biomeasure Inc

1996-07-03 Publication of SK15096A3 publication Critical patent/SK15096A3/sk

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
- C07K7/086—Bombesin; Related peptides
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/02—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/02—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
- A61P5/04—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin for decreasing, blocking or antagonising the activity of the hypothalamic hormones
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
- A61P5/08—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH for decreasing, blocking or antagonising the activity of the anterior pituitary hormones
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/14—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/18—Drugs for disorders of the endocrine system of the parathyroid hormones
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/655—Somatostatins
- C07K14/6555—Somatostatins at least 1 amino acid in D-form
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Diabetes (AREA)
Endocrinology (AREA)
Molecular Biology (AREA)
Biochemistry (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Genetics & Genomics (AREA)
Biophysics (AREA)
Immunology (AREA)
Hematology (AREA)
Gastroenterology & Hepatology (AREA)
Zoology (AREA)
Toxicology (AREA)
Virology (AREA)
Biomedical Technology (AREA)
AIDS & HIV (AREA)
Heart & Thoracic Surgery (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Vascular Medicine (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Ophthalmology & Optometry (AREA)
Cardiology (AREA)
Tropical Medicine & Parasitology (AREA)
Urology & Nephrology (AREA)

SK150-96A 1993-08-09 1994-08-08 Therapeutic peptide derivatives and a method of their application SK15096A3 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US10419493A	1993-08-09	1993-08-09
PCT/US1994/008875 WO1995004752A1 (en)	1993-08-09	1994-08-08	Therapeutic peptide derivatives

Publications (1)

Publication Number	Publication Date
SK15096A3 true SK15096A3 (en)	1996-07-03

Family

ID=22299154

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SK150-96A SK15096A3 (en)	1993-08-09	1994-08-08	Therapeutic peptide derivatives and a method of their application

Country Status (29)

Country	Link
US (1)	US5552520A (de)
EP (3)	EP1288224B1 (de)
JP (3)	JP3618750B2 (de)
KR (1)	KR100325972B1 (de)
CN (1)	CN1055700C (de)
AT (3)	ATE399177T1 (de)
AU (1)	AU689490B2 (de)
CA (1)	CA2168113C (de)
CZ (3)	CZ292586B6 (de)
DE (3)	DE69432758T2 (de)
DK (3)	DK1288223T3 (de)
ES (3)	ES2229045T3 (de)
FI (1)	FI960584A7 (de)
GE (1)	GEP20002146B (de)
HU (1)	HU224350B1 (de)
LT (1)	LT4078B (de)
LV (1)	LV11549B (de)
MD (1)	MD1591B2 (de)
NZ (1)	NZ271238A (de)
PL (1)	PL180612B1 (de)
PT (2)	PT788509E (de)
RO (1)	RO117259B1 (de)
RU (1)	RU2133252C1 (de)
SG (1)	SG75092A1 (de)
SI (2)	SI9420051A (de)
SK (1)	SK15096A3 (de)
UA (1)	UA44707C2 (de)
WO (1)	WO1995004752A1 (de)
ZA (1)	ZA945966B (de)

Families Citing this family (62)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JP2774769B2 (ja) *	1993-04-26	1998-07-09	賢治寒川	アドレノメデュリン
WO1996029343A1 (en) *	1995-03-20	1996-09-26	Kyowa Hakko Kogyo Co., Ltd.	Novel calcitonin derivatives
US5824772A (en) *	1995-04-04	1998-10-20	Advanced Bioconcept, Inc.	Fluorescent somatostatin
US6861053B1 (en)	1999-08-11	2005-03-01	Cedars-Sinai Medical Center	Methods of diagnosing or treating irritable bowel syndrome and other disorders caused by small intestinal bacterial overgrowth
US7048906B2 (en)	1995-05-17	2006-05-23	Cedars-Sinai Medical Center	Methods of diagnosing and treating small intestinal bacterial overgrowth (SIBO) and SIBO-related conditions
US6479457B2 (en)	1995-06-06	2002-11-12	Kinerton Limited	Ionic molecular conjugates of N-acylated derivatives of poly(2-amino-2-deoxy-D-glucose) and polypeptides
US5830431A (en) *	1995-06-07	1998-11-03	Mallinckrodt Medical, Inc.	Radiolabeled peptide compositions for site-specific targeting
US7410948B2 (en)	1995-07-13	2008-08-12	Societe De Conseils De Recherches Et D'applications Scientifiques, Sas	Analogs of parathyroid hormone
US6544949B1 (en)	1995-07-13	2003-04-08	Societe De Conseils De Recherches Et D'applications Scientifiques, S.A.S.	Analogs of parathyroid hormone
US5766620A (en) *	1995-10-23	1998-06-16	Theratech, Inc.	Buccal delivery of glucagon-like insulinotropic peptides
US7078413B2 (en)	1996-04-19	2006-07-18	Wisconsin Alumni Research Foundation	Compositions and methods of use for a bombesin peptide
US6492330B1 (en) *	1996-08-16	2002-12-10	National Institute Of Immunology	Antiangiogenic drugs
US5968903A (en) *	1998-05-07	1999-10-19	Biomeasure, Incorporated	Inhibition of H. pylori proliferation
US6124263A (en) *	1998-11-16	2000-09-26	Asta Medica Ag	Treatment of tumors by administration of growth hormone releasing compounds and their antagonists
US6864234B1 (en)	1999-06-25	2005-03-08	Societe De Conseils De Recherches Et D'applications Scientifiques, S.A.S.	Somatostatin agonists
CN1367792A (zh) *	1999-06-25	2002-09-04	研究及应用科学协会股份有限公司	促生长素抑制素激动剂
EP1348444B1 (de) *	1999-08-18	2006-04-12	Societe De Conseils De Recherches Et D'applications Scientifiques S.A.S.	Zusammensetzung mit verzögerter Abgabe in der ein Peptid mit einem Polymer komplexiert ist
AU2004200688B2 (en) *	1999-08-18	2007-01-25	Ipsen Pharma S.A.S.	Sustained release formulation of a peptide
JP4303438B2 (ja) *	1999-08-18	2009-07-29	ソシエテ・ドゥ・コンセイユ・ドゥ・ルシェルシュ・エ・ダプリカーション・シャンティフィック・エス・ア・エス	ペプチドの持続放出製剤
US7109166B1 (en) *	1999-08-18	2006-09-19	Societe De Conseils De Recherches Et D'applications Scientifiques, Sas	Sustained release formulation of a peptide
IES990700A2 (en)	1999-08-18	2001-08-22	Kinerton Ltd	Process to make a sustained release formulation
GB0018891D0 (en)	2000-08-01	2000-09-20	Novartis Ag	Organic compounds
US6316414B1 (en)	2000-07-31	2001-11-13	Dabur Research Foundation	Somatostatin analogs for the treatment of cancer
MD2074G2 (ro) *	2000-12-29	2003-06-30	Юрий НИКИТИН	Procedeu şi instalaţie de captare a vaporilor de carburant la staţiile de alimentare cu petrol, condensator al vaporilor de carburant utilizat în instalaţia menţionată
RU2352578C2 (ru)	2001-03-06	2009-04-20	Иль Консорцио Феррара Ричерке	Способ модуляции пролиферации клеток медуллярной карциномы щитовидной железы
DK1372688T3 (da) *	2001-03-08	2008-08-25	Univ Tulane	Somatostatin-antagonister
US20030229013A1 (en) *	2001-12-07	2003-12-11	Shih-Kwang Wu	Solid phase method for synthesis peptide-spacer-lipid conjugates, conjugates synthesized thereby and targeted liposomes containing the same
FR2833596B1 (fr) *	2001-12-14	2005-02-18	Aventis Pharma Sa	Procede de preparation de derives d'echinocandine
US20040171070A1 (en) *	2002-05-20	2004-09-02	Ramagauri Bhikhabhai	Peptide analysis using a solid support
US7166575B2 (en)	2002-12-17	2007-01-23	Nastech Pharmaceutical Company Inc.	Compositions and methods for enhanced mucosal delivery of peptide YY and methods for treating and preventing obesity
US7186692B2 (en)	2002-12-17	2007-03-06	Nastech Pharmaceutical Company Inc.	Compositions and methods for enhanced mucosal delivery and non-infused administration of Y2 receptor-binding peptides and methods for treating and preventing obesity
JP2006516262A (ja)	2002-12-17	2006-06-29	ナステック・ファーマシューティカル・カンパニー・インコーポレーテッド	Ｙ２受容体結合ペプチドの粘膜送達促進のための組成物および方法ならびに肥満症の治療法および予防法
US7229966B2 (en)	2002-12-17	2007-06-12	Nastech Pharmaceutical Company Inc.	Compositions and methods for enhanced mucosal delivery of Y2 receptor-binding peptides and methods for treating and preventing obesity
US7772188B2 (en)	2003-01-28	2010-08-10	Ironwood Pharmaceuticals, Inc.	Methods and compositions for the treatment of gastrointestinal disorders
US20090220587A1 (en) *	2005-02-01	2009-09-03	United State Army	Liposomal drug delivery constructs targeted by lipid-conjugated peptide ligands
US7741431B2 (en) *	2005-02-01	2010-06-22	The United States Of America As Represented By The Secretary Of The Army	Liposomes containing novel targeting and/or fusogenic peptides, preparations containing them and therapeutic use thereof
KR20080048502A (ko)	2005-09-29	2008-06-02	머크 앤드 캄파니 인코포레이티드	멜라노코르틴-4 수용체 조절제로서의 아실화스피로피페리딘 유도체
AU2007300627B2 (en)	2006-09-22	2012-02-16	Merck Sharp & Dohme Corp.	Method of treatment using fatty acid synthesis inhibitors
US8889632B2 (en)	2007-01-31	2014-11-18	Dana-Farber Cancer Institute, Inc.	Stabilized p53 peptides and uses thereof
EP2508531B1 (de)	2007-03-28	2016-10-19	President and Fellows of Harvard College	Geheftete Polypeptide
AU2008233662B2 (en)	2007-04-02	2012-08-23	Msd K.K.	Indoledione derivative
BRPI0915142A8 (pt)	2008-06-12	2018-01-02	Syntaxin Ltd	Polipeptídeos, ácido nucleico e usos dos mesmos
JP5728380B2 (ja)	2008-06-12	2015-06-03	シンタクシンリミテッドＳｙｎｔａｘｉｎＬｉｍｉｔｅｄ	神経内分泌疾患の抑制
GB0820970D0 (en)	2008-11-17	2008-12-24	Syntaxin Ltd	Suppression of cancer
EP2408472A4 (de) *	2009-03-18	2013-01-02	Univ Leland Stanford Junior	Verwendung von somatostatin oder einem analog davon in kombination mit einer externen strahlentherapie
EP3323423B1 (de)	2009-09-28	2020-06-17	Intarcia Therapeutics, Inc	Schnelle initiierung und/oder beendigung der verabreichung substantiell stabiler arzneimittel
CN102770152B (zh)	2009-11-25	2016-07-06	阿瑞斯根股份有限公司	肽类的粘膜递送
KR101915820B1 (ko)	2010-01-13	2018-11-06	입센 파마 에스.에이.에스	소마토스타틴 유사체의 지속 방출을 위한 제약 조성물의 제조 방법
CN102260352B (zh) *	2010-05-28	2013-11-20	山东先声麦得津生物制药有限公司	靶向性白细胞介素融合蛋白及其制备方法与应用
EP2399931A1 (de) *	2010-06-22	2011-12-28	Ipsen Pharma S.A.S.	Neue Oktapeptid-Verbindungen und ihr therapeutischer Einsatz
SI2603600T1 (sl)	2010-08-13	2019-04-30	Aileron Therapeutics, Inc.	Peptidomimetični makrocikli
TW201806968A (zh)	2011-10-18	2018-03-01	艾利倫治療公司	擬肽巨環化合物
HK1205454A1 (en)	2012-02-15	2015-12-18	Aileron Therapeutics, Inc.	Triazole-crosslinked and thioether-crosslinked peptidomimetic macrocycles
KR102112373B1 (ko)	2012-02-15	2020-05-18	에일러론 테라퓨틱스 인코포레이티드	펩티드모방체 마크로사이클
WO2014071241A1 (en)	2012-11-01	2014-05-08	Aileron Therapeutics, Inc.	Disubstituted amino acids and methods of preparation and use thereof
BR112017005598A2 (pt)	2014-09-24	2017-12-12	Aileron Therapeutics Inc	macrociclos peptidomiméticos e usos dos mesmos
WO2016154058A1 (en)	2015-03-20	2016-09-29	Aileron Therapeutics, Inc.	Peptidomimetic macrocycles and uses thereof
KR20240037175A (ko)	2016-05-16	2024-03-21	인타르시아 세라퓨틱스 인코포레이티드	글루카곤-수용체 선택적 폴리펩티드 및 이들의 이용 방법
CN108659100A (zh) *	2017-03-28	2018-10-16	上海新生源医药集团有限公司	具有镇痛作用的多肽及其应用
AU2019357621B2 (en)	2018-10-11	2025-04-03	Intarcia Therapeutics, Inc.	Human amylin analog polypeptides and methods of use
KR102740870B1 (ko) *	2020-08-05	2024-12-12	주식회사 레미바이오	아스코르브산 유도체 및 이를 포함하는 조성물
CN120329530A (zh) *	2024-01-16	2025-07-18	元素驱动(杭州)生物科技有限公司	含有环酰亚胺结构的聚酯聚合物

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CA1246055A (en) *	1980-03-24	1988-12-06	Joseph H. Cort	N-.omega.-substituted hormonogens of vasopressin and its synthetic analogs
DE3522638A1 (de) *	1985-06-25	1987-01-08	Diamalt Ag	Neue somatostatin-derivate
DE3614833A1 (de)	1986-01-16	1987-07-23	Hoechst Ag	Peptide mit vasorelaxierender, natriuretischer und diuretischer wirkung, verfahren zu ihrer herstellung, diese enthaltende mittel und ihre verwendung
HU206890B (en) *	1986-10-13	1993-01-28	Sandoz Ag	Process for producing sugar-modified somatostatin peptide derivatives and pharmaceutical compositions containing them as active components
DK163689A (da) *	1988-04-08	1989-10-30	Sandoz Ag	Peptidderivater
DE3910667A1 (de) *	1988-04-11	1989-10-19	Sandoz Ag	Peptidderivate
NO893088L (no)	1988-08-18	1990-02-19	Syntex Inc	Fremgangsmaate for fremstilling av terapeutisk virksomme somatostatinlignende cykliske peptidforbindelser.
BE1003762A3 (fr) *	1988-11-11	1992-06-09	Sandoz Sa	Nouvelle utilisation therapeutique de la somatostatine et de ses analogues et derives.
DE69024230T2 (de) *	1989-12-22	1996-05-02	Commw Scient Ind Res Org	An fette gebundene aminosäuren, peptide oder deren derivate
GB9209032D0 (en) *	1992-04-25	1992-06-10	Ciba Geigy Ag	New peptide derivatives

1994
- 1994-08-08 EP EP02026863A patent/EP1288224B1/de not_active Expired - Lifetime
- 1994-08-08 HU HU9600281A patent/HU224350B1/hu not_active IP Right Cessation
- 1994-08-08 CN CN94193717A patent/CN1055700C/zh not_active Expired - Fee Related
- 1994-08-08 DE DE69432758T patent/DE69432758T2/de not_active Expired - Lifetime
- 1994-08-08 RO RO96-00225A patent/RO117259B1/ro unknown
- 1994-08-08 RU RU96104340A patent/RU2133252C1/ru not_active IP Right Cessation
- 1994-08-08 CZ CZ1996390A patent/CZ292586B6/cs not_active IP Right Cessation
- 1994-08-08 ES ES02026862T patent/ES2229045T3/es not_active Expired - Lifetime
- 1994-08-08 ES ES94924590T patent/ES2196031T3/es not_active Expired - Lifetime
- 1994-08-08 DK DK02026862T patent/DK1288223T3/da active
- 1994-08-08 DK DK02026863T patent/DK1288224T3/da active
- 1994-08-08 FI FI960584A patent/FI960584A7/fi not_active Application Discontinuation
- 1994-08-08 DK DK94924590T patent/DK0788509T3/da active
- 1994-08-08 PT PT94924590T patent/PT788509E/pt unknown
- 1994-08-08 PL PL94312989A patent/PL180612B1/pl not_active IP Right Cessation
- 1994-08-08 PT PT02026862T patent/PT1288223E/pt unknown
- 1994-08-08 EP EP02026862A patent/EP1288223B1/de not_active Expired - Lifetime
- 1994-08-08 CA CA002168113A patent/CA2168113C/en not_active Expired - Fee Related
- 1994-08-08 WO PCT/US1994/008875 patent/WO1995004752A1/en not_active Ceased
- 1994-08-08 AT AT02026863T patent/ATE399177T1/de not_active IP Right Cessation
- 1994-08-08 EP EP94924590A patent/EP0788509B1/de not_active Expired - Lifetime
- 1994-08-08 DE DE69435105T patent/DE69435105D1/de not_active Expired - Lifetime
- 1994-08-08 UA UA96020456A patent/UA44707C2/uk unknown
- 1994-08-08 KR KR1019960700664A patent/KR100325972B1/ko not_active Expired - Fee Related
- 1994-08-08 MD MD96-0137A patent/MD1591B2/ro unknown
- 1994-08-08 SI SI9420051A patent/SI9420051A/sl unknown
- 1994-08-08 GE GEAP19943038A patent/GEP20002146B/en unknown
- 1994-08-08 SK SK150-96A patent/SK15096A3/sk unknown
- 1994-08-08 DE DE69434181T patent/DE69434181T2/de not_active Expired - Lifetime
- 1994-08-08 NZ NZ271238A patent/NZ271238A/en not_active IP Right Cessation
- 1994-08-08 ES ES02026863T patent/ES2309131T3/es not_active Expired - Lifetime
- 1994-08-08 JP JP50654195A patent/JP3618750B2/ja not_active Expired - Lifetime
- 1994-08-08 AU AU74819/94A patent/AU689490B2/en not_active Ceased
- 1994-08-08 AT AT02026862T patent/ATE284413T1/de not_active IP Right Cessation
- 1994-08-08 SG SG1996005779A patent/SG75092A1/en unknown
- 1994-08-08 AT AT94924590T patent/ATE241643T1/de not_active IP Right Cessation
- 1994-08-08 SI SI9430451T patent/SI0788509T1/xx unknown
- 1994-08-09 US US08/287,957 patent/US5552520A/en not_active Expired - Lifetime
- 1994-08-09 ZA ZA945966A patent/ZA945966B/xx unknown
1996
- 1996-03-06 LT LT96-025A patent/LT4078B/lt not_active IP Right Cessation
- 1996-03-08 LV LVP-96-71A patent/LV11549B/en unknown
2000
- 2000-03-22 CZ CZ20001033A patent/CZ289552B6/cs not_active IP Right Cessation
- 2000-03-22 CZ CZ20001032A patent/CZ289590B6/cs not_active IP Right Cessation
2004
- 2004-08-12 JP JP2004235535A patent/JP3785179B2/ja not_active Expired - Lifetime
- 2004-08-12 JP JP2004235503A patent/JP3869439B2/ja not_active Expired - Lifetime

Also Published As

Publication number	Publication date
LT4078B (en)	1996-12-27
JP3785179B2 (ja)	2006-06-14
CZ292586B6 (cs)	2003-10-15
DE69434181D1 (de)	2005-01-13
JP2005015488A (ja)	2005-01-20
PT1288223E (pt)	2005-03-31
GEP20002146B (en)	2000-06-25
DK1288223T3 (da)	2005-03-29
DE69432758T2 (de)	2004-02-19
HU9600281D0 (en)	1996-04-29
CZ39096A3 (en)	1996-11-13
WO1995004752A1 (en)	1995-02-16
CN1133047A (zh)	1996-10-09
JPH09501177A (ja)	1997-02-04
ES2196031T3 (es)	2003-12-16
UA44707C2 (uk)	2002-03-15
DE69434181T2 (de)	2005-12-01
DK1288224T3 (da)	2008-10-13
PL312989A1 (en)	1996-05-27
PT788509E (pt)	2003-10-31
CN1055700C (zh)	2000-08-23
PL180612B1 (pl)	2001-03-30
FI960584L (fi)	1996-02-08
LV11549B (en)	1997-04-20
DE69432758D1 (en)	2003-07-03
SI0788509T1 (en)	2003-10-31
FI960584A0 (fi)	1996-02-08
LV11549A (lv)	1996-10-20
AU689490B2 (en)	1998-04-02
AU7481994A (en)	1995-02-28
CA2168113C (en)	2002-10-01
HK1053313A1 (en)	2003-10-17
EP1288223A1 (de)	2003-03-05
MD960137A (en)	1999-01-31
MD1591B2 (ro)	2001-01-31
ATE241643T1 (de)	2003-06-15
EP1288224B1 (de)	2008-06-25
EP0788509B1 (de)	2003-05-28
JP3869439B2 (ja)	2007-01-17
DK0788509T3 (da)	2003-06-23
NZ271238A (en)	1997-10-24
ATE284413T1 (de)	2004-12-15
ZA945966B (en)	1995-06-26
RO117259B1 (ro)	2001-12-28
HUT73491A (en)	1996-08-28
KR100325972B1 (ko)	2002-07-27
HK1053314A1 (en)	2003-10-17
US5552520A (en)	1996-09-03
DE69435105D1 (de)	2008-08-07
EP0788509A4 (de)	1999-07-14
LT96025A (en)	1996-07-25
RU2133252C1 (ru)	1999-07-20
ES2229045T3 (es)	2005-04-16
CZ289552B6 (cs)	2002-02-13
ES2309131T3 (es)	2008-12-16
JP3618750B2 (ja)	2005-02-09
SI9420051A (en)	1996-12-31
JP2004339237A (ja)	2004-12-02
SG75092A1 (en)	2000-09-19
HU224350B1 (hu)	2005-08-29
ATE399177T1 (de)	2008-07-15
EP1288224A1 (de)	2003-03-05
CZ289590B6 (cs)	2002-02-13
CA2168113A1 (en)	1995-02-16
EP1288223B1 (de)	2004-12-08
EP0788509A1 (de)	1997-08-13
FI960584A7 (fi)	1996-02-08

Publication	Publication Date	Title
JP3785179B2 (ja)	2006-06-14	治療効果のあるペプチド誘導体
SK279231B6 (sk)	1998-08-05	Oktapeptid a terapeutický prostriedok s jeho obsah
JP3514754B2 (ja)	2004-03-31	肝臓癌の治療
HUT62604A (en)	1993-05-28	Process for producing peptides for treating tissue proliferation and pharmaceutical compositions comprising same
SK150196A3 (en)	1997-06-04	Peptides with immunomodulatory effects, pharmaceutical formulations containing them and their use
US6316414B1 (en)	2001-11-13	Somatostatin analogs for the treatment of cancer
HUT63178A (en)	1993-07-28	Process for producing bombesin antagonist polypeptides
IE903958A1 (en)	1991-05-08	Reduced irreversible bombesin antagonists
US6949513B2 (en)	2005-09-27	Polypeptides of covalently linked synthetic bioactive peptide analog(s) for treatment of cancer
MXPA00000455A (en)	2008-10-03	Therapeutic peptide derivatives
HK1053313B (en)	2005-06-03	Therapeutic peptide derivatives
HK1053314B (en)	2009-01-30	Therapeutic peptide derivatives
JPS63303999A (ja)	1988-12-12	バソプレシン拮抗剤