SK166798A3 - Peptide derivatives, process for their preparation, pharmaceutical composition them containing, and their use - Google Patents

Peptide derivatives, process for their preparation, pharmaceutical composition them containing, and their use Download PDF

Info

Publication number: SK166798A3
Authority: SK; Slovakia
Prior art keywords: formula; group; ala; amino acid; pharmaceutically acceptable
Prior art date: 1996-06-07

Application number

SK1667-98A

Other languages

English (en)

Slovak (sk)

Inventor

Ronald Cotton

Philip N Edwards

Richard W A Luke

Keith Oldham

Original Assignee

Zeneca Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1996-06-07

Filing date

1997-06-03

Publication date

1999-07-12

1996-06-07 Priority claimed from GBGB9611881.5A external-priority patent/GB9611881D0/en

1996-11-02 Priority claimed from GBGB9622890.3A external-priority patent/GB9622890D0/en

1997-06-03 Application filed by Zeneca Ltd filed Critical Zeneca Ltd

1999-07-12 Publication of SK166798A3 publication Critical patent/SK166798A3/sk

Links

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Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4713—Autoimmune diseases, e.g. Insulin-dependent diabetes mellitus, multiple sclerosis, rheumathoid arthritis, systemic lupus erythematosus; Autoantigens
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/02—Linear peptides containing at least one abnormal peptide link
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/82—Proteins from microorganisms
- Y10S530/825—Bacteria
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/827—Proteins from mammals or birds
- Y10S530/85—Reproductive organs or embryos
- Y10S530/851—Placenta; amniotic fluid

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Molecular Biology (AREA)
Biochemistry (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Genetics & Genomics (AREA)
Biophysics (AREA)
Rheumatology (AREA)
Immunology (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Toxicology (AREA)
Bioinformatics & Cheminformatics (AREA)
Gastroenterology & Hepatology (AREA)
Zoology (AREA)
Diabetes (AREA)
Hematology (AREA)
Rehabilitation Therapy (AREA)
Pain & Pain Management (AREA)
Physical Education & Sports Medicine (AREA)
Orthopedic Medicine & Surgery (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)

SK1667-98A 1996-06-07 1997-06-03 Peptide derivatives, process for their preparation, pharmaceutical composition them containing, and their use SK166798A3 (en)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
GBGB9611881.5A GB9611881D0 (en)	1996-06-07	1996-06-07	Peptide derivatives
GBGB9622890.3A GB9622890D0 (en)	1996-11-02	1996-11-02	Peptide compounds
PCT/GB1997/001491 WO1997046578A1 (en)	1996-06-07	1997-06-03	Peptide derivatives

Publications (1)

Publication Number	Publication Date
SK166798A3 true SK166798A3 (en)	1999-07-12

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ID=26309459

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SK1667-98A SK166798A3 (en)	1996-06-07	1997-06-03	Peptide derivatives, process for their preparation, pharmaceutical composition them containing, and their use

Country Status (21)

Country	Link
US (2)	US6541453B2 (de)
EP (1)	EP0914333B1 (de)
JP (1)	JP2000512277A (de)
KR (1)	KR100451522B1 (de)
CN (1)	CN1130372C (de)
AR (1)	AR008389A1 (de)
AT (1)	ATE283278T1 (de)
AU (1)	AU727757B2 (de)
BR (1)	BR9709533A (de)
CA (1)	CA2252417A1 (de)
DE (1)	DE69731747T2 (de)
HR (1)	HRP970308B1 (de)
ID (1)	ID17440A (de)
IL (1)	IL127332A0 (de)
NO (1)	NO985680L (de)
NZ (1)	NZ332347A (de)
PL (1)	PL330348A1 (de)
SK (1)	SK166798A3 (de)
TR (1)	TR199802537T2 (de)
TW (1)	TW474947B (de)
WO (1)	WO1997046578A1 (de)

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EP2951186B1 (de)	2013-01-29	2018-07-25	Aptinyx Inc.	Spiro-lactam-nmda-rezeptormodulatoren und verwendungen davon
US9758525B2 (en)	2013-01-29	2017-09-12	Aptinyx Inc.	Spiro-lactam NMDA receptor modulators and uses thereof
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KR102410989B1 (ko)	2013-01-29	2022-06-17	앱티닉스 인크.	스피로-락탐 nmda 수용체 조절인자 및 그의 용도
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PE20190174A1 (es)	2016-05-19	2019-02-01	Aptinyx Inc	Moduladores del receptor espiro-lactama n-metil-d-aspartato y usos de los mismos
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JP7036792B2 (ja)	2016-08-01	2022-03-15	アプティニックスインコーポレイテッド	スピロ－ラクタムｎｍｄａ受容体修飾因子およびその使用
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WO2018026798A1 (en)	2016-08-01	2018-02-08	Aptinyx Inc.	Spiro-lactam nmda modulators and methods of using same
AU2017306158B2 (en)	2016-08-01	2021-10-14	Aptinyx Inc.	Spiro-lactam and bis-spiro-lactam NMDA receptor modulators and uses thereof
KR102465758B1 (ko)	2016-08-01	2022-11-09	앱티닉스 인크.	스피로-락탐 nmda 수용체 조정제 및 그의 용도
PE20210455A1 (es)	2018-01-31	2021-03-08	Aptinyx Inc	Moduladores del receptor nmda espiro-lactama y usos de los mismos
CN109115899A (zh) *	2018-06-19	2019-01-01	南京肽业生物科技有限公司	一种Fmoc氨基酸的分析方法
US12012413B2 (en)	2019-11-11	2024-06-18	Tenacia Biotechnology (Hong Kong) Co., Limited	Methods of treating painful diabetic peripheral neuropathy
EP4141110A4 (de)	2020-04-24	2025-04-09	Sf Biotech Laboratuvar Danismanlik Anonim Sirketi	Verfahren zur herstellung von bakteriophagenteilchen der gattung levivirus

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1997
- 1997-06-03 TR TR1998/02537T patent/TR199802537T2/xx unknown
- 1997-06-03 AU AU29720/97A patent/AU727757B2/en not_active Ceased
- 1997-06-03 SK SK1667-98A patent/SK166798A3/sk unknown
- 1997-06-03 WO PCT/GB1997/001491 patent/WO1997046578A1/en not_active Ceased
- 1997-06-03 AT AT97924156T patent/ATE283278T1/de not_active IP Right Cessation
- 1997-06-03 BR BR9709533A patent/BR9709533A/pt not_active Application Discontinuation
- 1997-06-03 JP JP10500312A patent/JP2000512277A/ja not_active Ceased
- 1997-06-03 IL IL12733297A patent/IL127332A0/xx unknown
- 1997-06-03 DE DE69731747T patent/DE69731747T2/de not_active Expired - Fee Related
- 1997-06-03 CN CN97195216A patent/CN1130372C/zh not_active Expired - Fee Related
- 1997-06-03 EP EP97924156A patent/EP0914333B1/de not_active Expired - Lifetime
- 1997-06-03 CA CA002252417A patent/CA2252417A1/en not_active Abandoned
- 1997-06-03 PL PL97330348A patent/PL330348A1/xx unknown
- 1997-06-03 NZ NZ332347A patent/NZ332347A/xx unknown
- 1997-06-03 KR KR10-1998-0710049A patent/KR100451522B1/ko not_active Expired - Fee Related
- 1997-06-03 US US09/202,077 patent/US6541453B2/en not_active Expired - Fee Related
- 1997-06-04 HR HR970308A patent/HRP970308B1/xx not_active IP Right Cessation
- 1997-06-06 ID IDP971947A patent/ID17440A/id unknown
- 1997-06-06 AR ARP970102498A patent/AR008389A1/es unknown
- 1997-06-06 TW TW086107849A patent/TW474947B/zh not_active IP Right Cessation
1998
- 1998-12-04 NO NO985680A patent/NO985680L/no not_active Application Discontinuation
2002
- 2002-12-16 US US10/319,512 patent/US20030195158A1/en not_active Abandoned

Also Published As

Publication number	Publication date
AU2972097A (en)	1998-01-05
AU727757B2 (en)	2000-12-21
CN1221424A (zh)	1999-06-30
CN1130372C (zh)	2003-12-10
WO1997046578A1 (en)	1997-12-11
EP0914333B1 (de)	2004-11-24
TR199802537T2 (xx)	1999-03-22
DE69731747D1 (de)	2004-12-30
AR008389A1 (es)	2000-01-19
HRP970308A2 (en)	1998-04-30
IL127332A0 (en)	1999-09-22
CA2252417A1 (en)	1997-12-11
US20020103335A1 (en)	2002-08-01
NO985680L (no)	1999-02-04
DE69731747T2 (de)	2006-02-02
JP2000512277A (ja)	2000-09-19
PL330348A1 (en)	1999-05-10
NZ332347A (en)	2000-05-26
KR100451522B1 (ko)	2004-12-08
KR20000016465A (ko)	2000-03-25
NO985680D0 (no)	1998-12-04
ATE283278T1 (de)	2004-12-15
US6541453B2 (en)	2003-04-01
TW474947B (en)	2002-02-01
US20030195158A1 (en)	2003-10-16
EP0914333A1 (de)	1999-05-12
ID17440A (id)	1997-12-24
BR9709533A (pt)	1999-08-10
HRP970308B1 (en)	2002-04-30

Publication	Publication Date	Title
SK166798A3 (en)	1999-07-12	Peptide derivatives, process for their preparation, pharmaceutical composition them containing, and their use
CZ372698A3 (cs)	1999-06-16	Substituované imidazolidinové deriváty, způsob jejich přípravy, jejich použití a farmaceutické prostředky, které je obsahují
JP3468528B2 (ja)	2003-11-17	ペプチド誘導体
US6355617B1 (en)	2002-03-12	Peptide derivatives
US6207644B1 (en)	2001-03-27	Peptide analogues containing a 7-membered lactam ring
US6184207B1 (en)	2001-02-06	Inhibitors of peptide binding to MHC class II proteins
HUP0002215A2 (hu)	2000-12-28	Peptidszármazékok, eljárás ezek előállítására, ezeket tartalmazó gyógyszerkészítmények, valamint alkalmazásuk
HK1015383B (en)	2001-01-23	Peptide derivatives
Skarlas et al.	2009	HLA‐DQ7 β1 and β2 derived peptides as immunomodulators