SK2272002A3 - Alpha'v'beta'3' integrin inhibitors, process for the preparation and use thereof and pharmaceutical composition comprising same - Google Patents
Alpha'v'beta'3' integrin inhibitors, process for the preparation and use thereof and pharmaceutical composition comprising same Download PDFInfo
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- SK2272002A3 SK2272002A3 SK227-2002A SK2272002A SK2272002A3 SK 2272002 A3 SK2272002 A3 SK 2272002A3 SK 2272002 A SK2272002 A SK 2272002A SK 2272002 A3 SK2272002 A3 SK 2272002A3
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- ylamino
- phenyl
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
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- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/74—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4402—Non condensed pyridines; Hydrogenated derivatives thereof only substituted in position 2, e.g. pheniramine, bisacodyl
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- A61P35/04—Antineoplastic agents specific for metastasis
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Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Physical Education & Sports Medicine (AREA)
- Cardiology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Rheumatology (AREA)
- Heart & Thoracic Surgery (AREA)
- Ophthalmology & Optometry (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Dermatology (AREA)
- Urology & Nephrology (AREA)
- Hospice & Palliative Care (AREA)
- Pain & Pain Management (AREA)
- Virology (AREA)
- Vascular Medicine (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Pulmonology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19939980A DE19939980A1 (de) | 1999-08-24 | 1999-08-24 | Inhibitoren des Integrins alphavbeta¶3¶ |
| PCT/EP2000/007590 WO2001014337A1 (de) | 1999-08-24 | 2000-08-04 | INHIBITOREN DES INTEGRINS αvβ¿3? |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SK2272002A3 true SK2272002A3 (en) | 2002-06-04 |
Family
ID=7919342
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SK227-2002A SK2272002A3 (en) | 1999-08-24 | 2000-08-04 | Alpha'v'beta'3' integrin inhibitors, process for the preparation and use thereof and pharmaceutical composition comprising same |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US6645991B1 (pt) |
| EP (1) | EP1206455A1 (pt) |
| JP (1) | JP2003507457A (pt) |
| KR (1) | KR20020086849A (pt) |
| CN (1) | CN1370146A (pt) |
| AR (1) | AR034692A1 (pt) |
| AU (1) | AU6992500A (pt) |
| BR (1) | BR0013502A (pt) |
| CA (1) | CA2382561A1 (pt) |
| CZ (1) | CZ2002525A3 (pt) |
| DE (1) | DE19939980A1 (pt) |
| HK (1) | HK1049667A1 (pt) |
| HU (1) | HUP0203212A3 (pt) |
| MX (1) | MXPA02001862A (pt) |
| NO (1) | NO20020885D0 (pt) |
| PL (1) | PL352987A1 (pt) |
| SK (1) | SK2272002A3 (pt) |
| WO (1) | WO2001014337A1 (pt) |
| ZA (1) | ZA200202284B (pt) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0008696D0 (en) | 2000-04-07 | 2000-05-31 | Merck Sharp & Dohme | Therapeutic agents |
| UY26780A1 (es) | 2000-06-15 | 2002-01-31 | Pharmacia Corp | Cicloalquil avb3 antagonistas |
| US6531494B1 (en) | 2001-08-29 | 2003-03-11 | Pharmacia Corporation | Gem-substituted αvβ3 antagonists |
| DE10063173A1 (de) * | 2000-12-18 | 2002-06-20 | Merck Patent Gmbh | Harnstoff- und Urethanderivate |
| AU783516B2 (en) | 2001-04-30 | 2005-11-03 | Warner-Lambert Company | Methods, kits and compositions for using pyrrole derivatives |
| AU2002337954C1 (en) * | 2001-10-22 | 2008-10-23 | The Scripps Research Institute | Integrin targeting compounds |
| JP2007502300A (ja) * | 2003-08-13 | 2007-02-08 | カイロン コーポレイション | Ｇｓｋ−３インヒビターおよびその使用 |
| MXPA06014092A (es) | 2004-06-04 | 2007-03-15 | Scripps Research Inst | Composiciones y metodos para el tratamiento de enfermedades neovasculares. |
| WO2006111925A2 (en) * | 2005-04-18 | 2006-10-26 | Sloan-Kettering Institute For Cancer Research | Inhibition of tumorigenesis by inhibition of a6b4 integrin |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5234936A (en) * | 1991-10-24 | 1993-08-10 | American Home Products Corporation | Pyrimidocycloalkanes as a ii antagonists |
| US5654322A (en) * | 1992-08-11 | 1997-08-05 | Wakunaga Seiyaku Kabushiki Kaisha | Biphenylmethane derivatives and pharmaceuticals containing the same |
| EP0628559B1 (en) * | 1993-06-10 | 2002-04-03 | Beiersdorf-Lilly GmbH | Pyrimidine compounds and their use as pharmaceuticals |
| WO1997024124A1 (en) * | 1995-12-29 | 1997-07-10 | Smithkline Beecham Corporation | Vitronectin receptor antagonists |
| DE69706407T2 (de) * | 1996-03-29 | 2002-05-29 | G.D. Searle & Co., Chicago | META-SUBSTITUIERTE PHENYLENDERIVATE UND IHRE VERWENDUNG ALS ALPHAvBETA3 INTERGRIN-ANTAGONISTEN ODER INHIBITOREN |
| DE69717091T2 (de) | 1996-04-03 | 2003-07-31 | Takeda Chemical Industries, Ltd. | Oxazole derivate,ihre herstellung und verwendung |
| IL138245A0 (en) * | 1998-03-10 | 2001-10-31 | Smithkline Beecham Corp | Vitronectin receptor antagonists |
| IL145401A0 (en) | 1999-03-24 | 2002-06-30 | Anormed Inc | Chemokine receptor binding heterocyclic compounds |
-
1999
- 1999-08-24 DE DE19939980A patent/DE19939980A1/de not_active Withdrawn
-
2000
- 2000-08-04 CZ CZ2002525A patent/CZ2002525A3/cs unknown
- 2000-08-04 EP EP00958381A patent/EP1206455A1/de not_active Withdrawn
- 2000-08-04 US US10/069,187 patent/US6645991B1/en not_active Expired - Fee Related
- 2000-08-04 JP JP2001518426A patent/JP2003507457A/ja active Pending
- 2000-08-04 CN CN00811880A patent/CN1370146A/zh active Pending
- 2000-08-04 KR KR1020027001418A patent/KR20020086849A/ko not_active Withdrawn
- 2000-08-04 PL PL00352987A patent/PL352987A1/xx unknown
- 2000-08-04 AU AU69925/00A patent/AU6992500A/en not_active Abandoned
- 2000-08-04 BR BR0013502-0A patent/BR0013502A/pt not_active IP Right Cessation
- 2000-08-04 SK SK227-2002A patent/SK2272002A3/sk unknown
- 2000-08-04 HK HK03101817.6A patent/HK1049667A1/zh unknown
- 2000-08-04 HU HU0203212A patent/HUP0203212A3/hu unknown
- 2000-08-04 WO PCT/EP2000/007590 patent/WO2001014337A1/de not_active Ceased
- 2000-08-04 CA CA002382561A patent/CA2382561A1/en not_active Abandoned
- 2000-08-04 MX MXPA02001862A patent/MXPA02001862A/es unknown
- 2000-08-23 AR ARP000104353A patent/AR034692A1/es not_active Application Discontinuation
-
2002
- 2002-02-22 NO NO20020885A patent/NO20020885D0/no not_active Application Discontinuation
- 2002-03-20 ZA ZA200202284A patent/ZA200202284B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| HK1049667A1 (zh) | 2003-05-23 |
| NO20020885L (no) | 2002-02-22 |
| EP1206455A1 (de) | 2002-05-22 |
| CN1370146A (zh) | 2002-09-18 |
| ZA200202284B (en) | 2003-08-27 |
| HUP0203212A2 (hu) | 2003-02-28 |
| AU6992500A (en) | 2001-03-19 |
| MXPA02001862A (es) | 2002-10-23 |
| CZ2002525A3 (cs) | 2002-05-15 |
| CA2382561A1 (en) | 2001-03-01 |
| US6645991B1 (en) | 2003-11-11 |
| PL352987A1 (en) | 2003-09-22 |
| NO20020885D0 (no) | 2002-02-22 |
| JP2003507457A (ja) | 2003-02-25 |
| DE19939980A1 (de) | 2001-03-01 |
| KR20020086849A (ko) | 2002-11-20 |
| BR0013502A (pt) | 2002-05-07 |
| HUP0203212A3 (en) | 2005-02-28 |
| AR034692A1 (es) | 2004-03-17 |
| WO2001014337A1 (de) | 2001-03-01 |
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