SK5984Y1 - Dietary supplement the increasing protection of the epithelium of the lower urinary tract before repeated infections - Google Patents

Dietary supplement the increasing protection of the epithelium of the lower urinary tract before repeated infections Download PDF

Info

Publication number: SK5984Y1
Authority: SK; Slovakia
Prior art keywords: dietary supplement; supplement according; group; mixtures; mixture
Prior art date: 2011-03-07

Application number

SK50048-2011U

Other languages

English (en)

Slovak (sk)

Other versions

SK500482011U1 (en

Inventor

Richard Reichenbach

Vilim Simanek

Jitka Ulrichova

Original Assignee

Walmark A S

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2011-03-07

Filing date

2011-04-28

Publication date

2012-01-04

2011-04-28 Application filed by Walmark A S filed Critical Walmark A S

2011-07-06 Publication of SK500482011U1 publication Critical patent/SK500482011U1/sk

2012-01-04 Publication of SK5984Y1 publication Critical patent/SK5984Y1/sk

Links

235000015872 dietary supplement Nutrition 0.000 title claims abstract description 30
210000001635 urinary tract Anatomy 0.000 title description 9
210000000981 epithelium Anatomy 0.000 title description 5
230000001965 increasing effect Effects 0.000 title description 4
208000015181 infectious disease Diseases 0.000 title description 4
239000000203 mixture Substances 0.000 claims abstract description 31
240000001717 Vaccinium macrocarpon Species 0.000 claims abstract description 23
QYSXJUFSXHHAJI-XFEUOLMDSA-N Vitamin D3 Natural products C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)CCCC(C)C)=C/C=C1\C[C@@H](O)CCC1=C QYSXJUFSXHHAJI-XFEUOLMDSA-N 0.000 claims abstract description 15
235000011389 fruit/vegetable juice Nutrition 0.000 claims abstract description 14
235000019166 vitamin D Nutrition 0.000 claims abstract description 13
239000011710 vitamin D Substances 0.000 claims abstract description 13
229930003316 Vitamin D Natural products 0.000 claims abstract description 12
150000003710 vitamin D derivatives Chemical class 0.000 claims abstract description 12
MECHNRXZTMCUDQ-RKHKHRCZSA-N vitamin D2 Chemical compound C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)/C=C/[C@H](C)C(C)C)=C\C=C1\C[C@@H](O)CCC1=C MECHNRXZTMCUDQ-RKHKHRCZSA-N 0.000 claims abstract description 12
229940046008 vitamin d Drugs 0.000 claims abstract description 12
MECHNRXZTMCUDQ-UHFFFAOYSA-N Vitamin D2 Natural products C1CCC2(C)C(C(C)C=CC(C)C(C)C)CCC2C1=CC=C1CC(O)CCC1=C MECHNRXZTMCUDQ-UHFFFAOYSA-N 0.000 claims abstract description 11
229960002061 ergocalciferol Drugs 0.000 claims abstract description 11
235000001892 vitamin D2 Nutrition 0.000 claims abstract description 11
239000011653 vitamin D2 Substances 0.000 claims abstract description 11
239000003963 antioxidant agent Substances 0.000 claims abstract description 10
239000002904 solvent Substances 0.000 claims abstract description 9
QYSXJUFSXHHAJI-YRZJJWOYSA-N vitamin D3 Chemical compound C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)CCCC(C)C)=C\C=C1\C[C@@H](O)CCC1=C QYSXJUFSXHHAJI-YRZJJWOYSA-N 0.000 claims abstract description 9
239000003795 chemical substances by application Substances 0.000 claims abstract description 8
239000003995 emulsifying agent Substances 0.000 claims abstract description 6
239000003381 stabilizer Substances 0.000 claims abstract description 6
239000000284 extract Substances 0.000 claims abstract description 4
PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 18
235000006708 antioxidants Nutrition 0.000 claims description 9
210000003741 urothelium Anatomy 0.000 claims description 9
VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims description 8
239000000546 pharmaceutical excipient Substances 0.000 claims description 8
230000003078 antioxidant effect Effects 0.000 claims description 7
239000004014 plasticizer Substances 0.000 claims description 7
LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 6
UQSXHKLRYXJYBZ-UHFFFAOYSA-N Iron oxide Chemical compound [Fe]=O UQSXHKLRYXJYBZ-UHFFFAOYSA-N 0.000 claims description 6
GWEVSGVZZGPLCZ-UHFFFAOYSA-N Titan oxide Chemical compound O=[Ti]=O GWEVSGVZZGPLCZ-UHFFFAOYSA-N 0.000 claims description 6
239000004480 active ingredient Substances 0.000 claims description 6
235000011187 glycerol Nutrition 0.000 claims description 6
HQKMJHAJHXVSDF-UHFFFAOYSA-L magnesium stearate Chemical compound [Mg+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O HQKMJHAJHXVSDF-UHFFFAOYSA-L 0.000 claims description 6
108010010803 Gelatin Proteins 0.000 claims description 5
235000021019 cranberries Nutrition 0.000 claims description 5
229920000159 gelatin Polymers 0.000 claims description 5
239000008273 gelatin Substances 0.000 claims description 5
235000019322 gelatine Nutrition 0.000 claims description 5
235000011852 gelatine desserts Nutrition 0.000 claims description 5
235000010378 sodium ascorbate Nutrition 0.000 claims description 5
PPASLZSBLFJQEF-RKJRWTFHSA-M sodium ascorbate Substances [Na+].OC[C@@H](O)[C@H]1OC(=O)C(O)=C1[O-] PPASLZSBLFJQEF-RKJRWTFHSA-M 0.000 claims description 5
229960005055 sodium ascorbate Drugs 0.000 claims description 5
PPASLZSBLFJQEF-RXSVEWSESA-M sodium-L-ascorbate Chemical compound [Na+].OC[C@H](O)[C@H]1OC(=O)C(O)=C1[O-] PPASLZSBLFJQEF-RXSVEWSESA-M 0.000 claims description 5
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 5
208000035415 Reinfection Diseases 0.000 claims description 4
239000003086 colorant Substances 0.000 claims description 4
239000000377 silicon dioxide Substances 0.000 claims description 4
CDBYLPFSWZWCQE-UHFFFAOYSA-L sodium carbonate Substances [Na+].[Na+].[O-]C([O-])=O CDBYLPFSWZWCQE-UHFFFAOYSA-L 0.000 claims description 4
239000000126 substance Substances 0.000 claims description 4
239000006188 syrup Substances 0.000 claims description 4
235000020357 syrup Nutrition 0.000 claims description 4
229920002153 Hydroxypropyl cellulose Polymers 0.000 claims description 3
229910019142 PO4 Inorganic materials 0.000 claims description 3
235000013871 bee wax Nutrition 0.000 claims description 3
239000012166 beeswax Substances 0.000 claims description 3
239000012141 concentrate Substances 0.000 claims description 3
235000008504 concentrate Nutrition 0.000 claims description 3
239000001863 hydroxypropyl cellulose Substances 0.000 claims description 3
235000010977 hydroxypropyl cellulose Nutrition 0.000 claims description 3
235000010445 lecithin Nutrition 0.000 claims description 3
239000000787 lecithin Substances 0.000 claims description 3
235000019359 magnesium stearate Nutrition 0.000 claims description 3
235000021317 phosphate Nutrition 0.000 claims description 3
150000003013 phosphoric acid derivatives Chemical class 0.000 claims description 3
150000003077 polyols Chemical class 0.000 claims description 3
239000004408 titanium dioxide Substances 0.000 claims description 3
235000015112 vegetable and seed oil Nutrition 0.000 claims description 3
239000008158 vegetable oil Substances 0.000 claims description 3
235000013311 vegetables Nutrition 0.000 claims description 3
XZIIFPSPUDAGJM-UHFFFAOYSA-N 6-chloro-2-n,2-n-diethylpyrimidine-2,4-diamine Chemical compound CCN(CC)C1=NC(N)=CC(Cl)=N1 XZIIFPSPUDAGJM-UHFFFAOYSA-N 0.000 claims description 2
OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 claims description 2
FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 claims description 2
FBPFZTCFMRRESA-JGWLITMVSA-N D-glucitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-JGWLITMVSA-N 0.000 claims description 2
239000011786 L-ascorbyl-6-palmitate Substances 0.000 claims description 2
QAQJMLQRFWZOBN-LAUBAEHRSA-N L-ascorbyl-6-palmitate Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](O)[C@H]1OC(=O)C(O)=C1O QAQJMLQRFWZOBN-LAUBAEHRSA-N 0.000 claims description 2
229920000881 Modified starch Polymers 0.000 claims description 2
239000004368 Modified starch Substances 0.000 claims description 2
239000002202 Polyethylene glycol Substances 0.000 claims description 2
239000004372 Polyvinyl alcohol Substances 0.000 claims description 2
229920001800 Shellac Polymers 0.000 claims description 2
IYFATESGLOUGBX-YVNJGZBMSA-N Sorbitan monopalmitate Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@@H](O)[C@H]1OC[C@H](O)[C@H]1O IYFATESGLOUGBX-YVNJGZBMSA-N 0.000 claims description 2
HVUMOYIDDBPOLL-XWVZOOPGSA-N Sorbitan monostearate Chemical compound CCCCCCCCCCCCCCCCCC(=O)OC[C@@H](O)[C@H]1OC[C@H](O)[C@H]1O HVUMOYIDDBPOLL-XWVZOOPGSA-N 0.000 claims description 2
229920002472 Starch Polymers 0.000 claims description 2
239000002253 acid Substances 0.000 claims description 2
235000010385 ascorbyl palmitate Nutrition 0.000 claims description 2
VTYYLEPIZMXCLO-UHFFFAOYSA-L calcium carbonate Substances [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 claims description 2
239000000679 carrageenan Substances 0.000 claims description 2
235000010418 carrageenan Nutrition 0.000 claims description 2
229920001525 carrageenan Polymers 0.000 claims description 2
229940113118 carrageenan Drugs 0.000 claims description 2
235000010980 cellulose Nutrition 0.000 claims description 2
229920002678 cellulose Polymers 0.000 claims description 2
235000014113 dietary fatty acids Nutrition 0.000 claims description 2
239000000194 fatty acid Substances 0.000 claims description 2
229930195729 fatty acid Natural products 0.000 claims description 2
239000001866 hydroxypropyl methyl cellulose Substances 0.000 claims description 2
235000010979 hydroxypropyl methyl cellulose Nutrition 0.000 claims description 2
229920003088 hydroxypropyl methyl cellulose Polymers 0.000 claims description 2
UFVKGYZPFZQRLF-UHFFFAOYSA-N hydroxypropyl methyl cellulose Chemical compound OC1C(O)C(OC)OC(CO)C1OC1C(O)C(O)C(OC2C(C(O)C(OC3C(C(O)C(O)C(CO)O3)O)C(CO)O2)O)C(CO)O1 UFVKGYZPFZQRLF-UHFFFAOYSA-N 0.000 claims description 2
235000019426 modified starch Nutrition 0.000 claims description 2
229920001223 polyethylene glycol Polymers 0.000 claims description 2
229920000223 polyglycerol Polymers 0.000 claims description 2
229920005862 polyol Polymers 0.000 claims description 2
229920000136 polysorbate Polymers 0.000 claims description 2
229940068965 polysorbates Drugs 0.000 claims description 2
229920002451 polyvinyl alcohol Polymers 0.000 claims description 2
239000004208 shellac Substances 0.000 claims description 2
ZLGIYFNHBLSMPS-ATJNOEHPSA-N shellac Chemical compound OCCCCCC(O)C(O)CCCCCCCC(O)=O.C1C23[C@H](C(O)=O)CCC2[C@](C)(CO)[C@@H]1C(C(O)=O)=C[C@@H]3O ZLGIYFNHBLSMPS-ATJNOEHPSA-N 0.000 claims description 2
229940113147 shellac Drugs 0.000 claims description 2
235000013874 shellac Nutrition 0.000 claims description 2
229940035044 sorbitan monolaurate Drugs 0.000 claims description 2
239000001570 sorbitan monopalmitate Substances 0.000 claims description 2
235000011071 sorbitan monopalmitate Nutrition 0.000 claims description 2
229940031953 sorbitan monopalmitate Drugs 0.000 claims description 2
239000001587 sorbitan monostearate Substances 0.000 claims description 2
235000011076 sorbitan monostearate Nutrition 0.000 claims description 2
229940035048 sorbitan monostearate Drugs 0.000 claims description 2
239000000600 sorbitol Substances 0.000 claims description 2
229960002920 sorbitol Drugs 0.000 claims description 2
239000008107 starch Substances 0.000 claims description 2
235000019698 starch Nutrition 0.000 claims description 2
229930003799 tocopherol Natural products 0.000 claims description 2
239000011732 tocopherol Substances 0.000 claims description 2
235000019149 tocopherols Nutrition 0.000 claims description 2
150000003626 triacylglycerols Chemical class 0.000 claims description 2
UHVMMEOXYDMDKI-JKYCWFKZSA-L zinc;1-(5-cyanopyridin-2-yl)-3-[(1s,2s)-2-(6-fluoro-2-hydroxy-3-propanoylphenyl)cyclopropyl]urea;diacetate Chemical compound [Zn+2].CC([O-])=O.CC([O-])=O.CCC(=O)C1=CC=C(F)C([C@H]2[C@H](C2)NC(=O)NC=2N=CC(=CC=2)C#N)=C1O UHVMMEOXYDMDKI-JKYCWFKZSA-L 0.000 claims description 2
QUEDXNHFTDJVIY-UHFFFAOYSA-N γ-tocopherol Chemical class OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1 QUEDXNHFTDJVIY-UHFFFAOYSA-N 0.000 claims description 2
229910052791 calcium Inorganic materials 0.000 claims 1
235000010216 calcium carbonate Nutrition 0.000 claims 1
239000001506 calcium phosphate Substances 0.000 claims 1
235000011010 calcium phosphates Nutrition 0.000 claims 1
230000002708 enhancing effect Effects 0.000 claims 1
150000002148 esters Chemical class 0.000 claims 1
150000004665 fatty acids Chemical class 0.000 claims 1
235000011182 sodium carbonates Nutrition 0.000 claims 1
QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical class [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 claims 1
235000012545 Vaccinium macrocarpon Nutrition 0.000 abstract description 18
235000004634 cranberry Nutrition 0.000 abstract description 18
235000002118 Vaccinium oxycoccus Nutrition 0.000 abstract description 14
235000013399 edible fruits Nutrition 0.000 abstract description 7
239000002671 adjuvant Substances 0.000 abstract description 3
239000004150 EU approved colour Substances 0.000 abstract 1
239000004902 Softening Agent Substances 0.000 abstract 1
239000000084 colloidal system Substances 0.000 abstract 1
239000010408 film Substances 0.000 abstract 1
229940006093 opthalmologic coloring agent diagnostic Drugs 0.000 abstract 1
230000000694 effects Effects 0.000 description 8
239000003981 vehicle Substances 0.000 description 7
241000894006 Bacteria Species 0.000 description 5
239000013543 active substance Substances 0.000 description 5
239000000843 powder Substances 0.000 description 4
JWUBBDSIWDLEOM-XHQRYOPUSA-N (3e)-3-[(2e)-2-[1-(6-hydroxy-6-methylheptan-2-yl)-7a-methyl-2,3,3a,5,6,7-hexahydro-1h-inden-4-ylidene]ethylidene]-4-methylidenecyclohexan-1-ol Chemical compound C1CCC2(C)C(C(CCCC(C)(C)O)C)CCC2\C1=C\C=C1/CC(O)CCC1=C JWUBBDSIWDLEOM-XHQRYOPUSA-N 0.000 description 3
235000021318 Calcifediol Nutrition 0.000 description 3
206010047626 Vitamin D Deficiency Diseases 0.000 description 3
108060001132 cathelicidin Proteins 0.000 description 3
102000014509 cathelicidin Human genes 0.000 description 3
235000013305 food Nutrition 0.000 description 3
239000004615 ingredient Substances 0.000 description 3
208000019206 urinary tract infection Diseases 0.000 description 3
235000005282 vitamin D3 Nutrition 0.000 description 3
239000011647 vitamin D3 Substances 0.000 description 3
229940021056 vitamin d3 Drugs 0.000 description 3
208000024172 Cardiovascular disease Diseases 0.000 description 2
208000035473 Communicable disease Diseases 0.000 description 2
230000005784 autoimmunity Effects 0.000 description 2
230000009286 beneficial effect Effects 0.000 description 2
230000032770 biofilm formation Effects 0.000 description 2
239000008280 blood Substances 0.000 description 2
210000004369 blood Anatomy 0.000 description 2
210000000988 bone and bone Anatomy 0.000 description 2
239000002775 capsule Substances 0.000 description 2
239000000975 dye Substances 0.000 description 2
235000015203 fruit juice Nutrition 0.000 description 2
239000000047 product Substances 0.000 description 2
238000012552 review Methods 0.000 description 2
210000003932 urinary bladder Anatomy 0.000 description 2
230000002485 urinary effect Effects 0.000 description 2
IIZPXYDJLKNOIY-JXPKJXOSSA-N 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCC\C=C/C\C=C/C\C=C/C\C=C/CCCCC IIZPXYDJLKNOIY-JXPKJXOSSA-N 0.000 description 1
208000023275 Autoimmune disease Diseases 0.000 description 1
208000035143 Bacterial infection Diseases 0.000 description 1
208000010392 Bone Fractures Diseases 0.000 description 1
229920002134 Carboxymethyl cellulose Polymers 0.000 description 1
206010009944 Colon cancer Diseases 0.000 description 1
229920000742 Cotton Polymers 0.000 description 1
ZAKOWWREFLAJOT-CEFNRUSXSA-N D-alpha-tocopherylacetate Chemical compound CC(=O)OC1=C(C)C(C)=C2O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1C ZAKOWWREFLAJOT-CEFNRUSXSA-N 0.000 description 1
241000588724 Escherichia coli Species 0.000 description 1
241000590002 Helicobacter pylori Species 0.000 description 1
208000037147 Hypercalcaemia Diseases 0.000 description 1
229920000168 Microcrystalline cellulose Polymers 0.000 description 1
206010028980 Neoplasm Diseases 0.000 description 1
208000001132 Osteoporosis Diseases 0.000 description 1
206010067584 Type 1 diabetes mellitus Diseases 0.000 description 1
235000012511 Vaccinium Nutrition 0.000 description 1
241000736767 Vaccinium Species 0.000 description 1
230000001154 acute effect Effects 0.000 description 1
208000038016 acute inflammation Diseases 0.000 description 1
230000006022 acute inflammation Effects 0.000 description 1
235000010208 anthocyanin Nutrition 0.000 description 1
239000004410 anthocyanin Substances 0.000 description 1
229930002877 anthocyanin Natural products 0.000 description 1
150000004636 anthocyanins Chemical class 0.000 description 1
239000003242 anti bacterial agent Substances 0.000 description 1
230000000181 anti-adherent effect Effects 0.000 description 1
230000000844 anti-bacterial effect Effects 0.000 description 1
230000003110 anti-inflammatory effect Effects 0.000 description 1
229940088710 antibiotic agent Drugs 0.000 description 1
208000022362 bacterial infectious disease Diseases 0.000 description 1
244000052616 bacterial pathogen Species 0.000 description 1
230000033228 biological regulation Effects 0.000 description 1
230000033558 biomineral tissue development Effects 0.000 description 1
230000015572 biosynthetic process Effects 0.000 description 1
230000008468 bone growth Effects 0.000 description 1
229910000019 calcium carbonate Inorganic materials 0.000 description 1
FUFJGUQYACFECW-UHFFFAOYSA-L calcium hydrogenphosphate Chemical compound [Ca+2].OP([O-])([O-])=O FUFJGUQYACFECW-UHFFFAOYSA-L 0.000 description 1
230000003913 calcium metabolism Effects 0.000 description 1
159000000007 calcium salts Chemical class 0.000 description 1
201000011510 cancer Diseases 0.000 description 1
239000001768 carboxy methyl cellulose Substances 0.000 description 1
235000010948 carboxy methyl cellulose Nutrition 0.000 description 1
239000008112 carboxymethyl-cellulose Substances 0.000 description 1
POIUWJQBRNEFGX-XAMSXPGMSA-N cathelicidin Chemical compound C([C@@H](C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CC=1C=CC=CC=1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N1[C@@H](CCC1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCC(O)=O)C(=O)N[C@@H](CO)C(O)=O)NC(=O)[C@H](CC=1C=CC=CC=1)NC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@H](CC(C)C)NC(=O)[C@@H](N)CC(C)C)C1=CC=CC=C1 POIUWJQBRNEFGX-XAMSXPGMSA-N 0.000 description 1
229940112822 chewing gum Drugs 0.000 description 1
235000015218 chewing gum Nutrition 0.000 description 1
208000029742 colonic neoplasm Diseases 0.000 description 1
235000020237 cranberry extract Nutrition 0.000 description 1
235000019700 dicalcium phosphate Nutrition 0.000 description 1
229940095079 dicalcium phosphate anhydrous Drugs 0.000 description 1
230000008029 eradication Effects 0.000 description 1
-1 fatty acid esters Chemical class 0.000 description 1
239000007941 film coated tablet Substances 0.000 description 1
229930003935 flavonoid Natural products 0.000 description 1
235000017173 flavonoids Nutrition 0.000 description 1
150000002215 flavonoids Chemical class 0.000 description 1
235000013376 functional food Nutrition 0.000 description 1
210000001156 gastric mucosa Anatomy 0.000 description 1
210000001035 gastrointestinal tract Anatomy 0.000 description 1
229940037467 helicobacter pylori Drugs 0.000 description 1
230000013632 homeostatic process Effects 0.000 description 1
239000005556 hormone Substances 0.000 description 1
229940088597 hormone Drugs 0.000 description 1
230000000148 hypercalcaemia Effects 0.000 description 1
230000006698 induction Effects 0.000 description 1
230000001939 inductive effect Effects 0.000 description 1
239000003112 inhibitor Substances 0.000 description 1
230000002401 inhibitory effect Effects 0.000 description 1
230000005764 inhibitory process Effects 0.000 description 1
229910052500 inorganic mineral Inorganic materials 0.000 description 1
235000015110 jellies Nutrition 0.000 description 1
229940067606 lecithin Drugs 0.000 description 1
239000007788 liquid Substances 0.000 description 1
229930185824 macrocarpon Natural products 0.000 description 1
230000000813 microbial effect Effects 0.000 description 1
229940016286 microcrystalline cellulose Drugs 0.000 description 1
235000019813 microcrystalline cellulose Nutrition 0.000 description 1
239000008108 microcrystalline cellulose Substances 0.000 description 1
239000011707 mineral Substances 0.000 description 1
235000010755 mineral Nutrition 0.000 description 1
231100000957 no side effect Toxicity 0.000 description 1
239000003921 oil Substances 0.000 description 1
235000019198 oils Nutrition 0.000 description 1
230000000144 pharmacologic effect Effects 0.000 description 1
235000009048 phenolic acids Nutrition 0.000 description 1
150000007965 phenolic acids Chemical class 0.000 description 1
150000008442 polyphenolic compounds Chemical class 0.000 description 1
235000013824 polyphenols Nutrition 0.000 description 1
238000002360 preparation method Methods 0.000 description 1
230000002265 prevention Effects 0.000 description 1
108090000765 processed proteins & peptides Proteins 0.000 description 1
108090000623 proteins and genes Proteins 0.000 description 1
229940126409 proton pump inhibitor Drugs 0.000 description 1
239000000612 proton pump inhibitor Substances 0.000 description 1
230000000306 recurrent effect Effects 0.000 description 1
230000009711 regulatory function Effects 0.000 description 1
238000007634 remodeling Methods 0.000 description 1
239000011347 resin Substances 0.000 description 1
229920005989 resin Polymers 0.000 description 1
150000003839 salts Chemical class 0.000 description 1
230000011664 signaling Effects 0.000 description 1
235000012239 silicon dioxide Nutrition 0.000 description 1
229910000029 sodium carbonate Inorganic materials 0.000 description 1
239000007901 soft capsule Substances 0.000 description 1
235000012424 soybean oil Nutrition 0.000 description 1
239000003549 soybean oil Substances 0.000 description 1
239000007921 spray Substances 0.000 description 1
239000013589 supplement Substances 0.000 description 1
230000009469 supplementation Effects 0.000 description 1
238000003786 synthesis reaction Methods 0.000 description 1
230000009885 systemic effect Effects 0.000 description 1
239000003826 tablet Substances 0.000 description 1
229940042585 tocopherol acetate Drugs 0.000 description 1
210000002700 urine Anatomy 0.000 description 1
229940088594 vitamin Drugs 0.000 description 1
229930003231 vitamin Natural products 0.000 description 1
235000013343 vitamin Nutrition 0.000 description 1
239000011782 vitamin Substances 0.000 description 1
239000011719 vitamin A Substances 0.000 description 1
235000019155 vitamin A Nutrition 0.000 description 1
235000019156 vitamin B Nutrition 0.000 description 1
239000011720 vitamin B Substances 0.000 description 1
235000019154 vitamin C Nutrition 0.000 description 1
239000011718 vitamin C Substances 0.000 description 1
239000011709 vitamin E Substances 0.000 description 1
235000019165 vitamin E Nutrition 0.000 description 1
238000005303 weighing Methods 0.000 description 1

Landscapes

Medicinal Preparation (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines Containing Plant Substances (AREA)
Coloring Foods And Improving Nutritive Qualities (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

SK50048-2011U 2011-03-07 2011-04-28 Dietary supplement the increasing protection of the epithelium of the lower urinary tract before repeated infections SK5984Y1 (sk)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
CZ201124019U CZ22065U1 (cs)	2011-03-07	2011-03-07	Doplnek stravy zvyšující ochranu epitelu dolních cest mocových pred opakovanými infekcemi

Publications (2)

Publication Number	Publication Date
SK500482011U1 SK500482011U1 (en)	2011-07-06
SK5984Y1 true SK5984Y1 (sk)	2012-01-04

Family

ID=43875526

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SK50048-2011U SK5984Y1 (sk)	2011-03-07	2011-04-28	Dietary supplement the increasing protection of the epithelium of the lower urinary tract before repeated infections

Country Status (6)

Country	Link
BG (1)	BG1474U1 (cs)
CZ (1)	CZ22065U1 (cs)
LV (1)	LV14567B (cs)
PL (1)	PL394996A1 (cs)
RO (1)	RO201100020U1 (cs)
SK (1)	SK5984Y1 (cs)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ATE282326T1 (de) *	1998-03-04	2004-12-15	Dandy As	Beschichteter kaugummi, verfahren zur herstellung und verwendung von einem oder mehreren festen aktiven stoffen
RU2242145C1 (ru) *	2003-12-23	2004-12-20	ООО "Закрома Подмосковья"	Кисель витаминизированный
EA012467B1 (ru) *	2007-10-05	2009-10-30	Открытое Акционерное Общество "Прогресс"	Соус для детского питания
CN101590093A (zh) *	2008-10-08	2009-12-02	北京冠五洲生物科学研究院	用于预防出生缺陷和改善记忆的药物组合物

2011
- 2011-03-07 CZ CZ201124019U patent/CZ22065U1/cs not_active IP Right Cessation
- 2011-04-28 SK SK50048-2011U patent/SK5984Y1/sk unknown
- 2011-05-10 BG BG1992U patent/BG1474U1/bg unknown
- 2011-05-10 RO ROU201100020U patent/RO201100020U1/ro unknown
- 2011-05-19 LV LVP-11-72A patent/LV14567B/lv unknown
- 2011-05-23 PL PL394996A patent/PL394996A1/pl unknown

Also Published As

Publication number	Publication date
RO201100020U1 (ro)	2012-07-30
PL394996A1 (pl)	2012-09-10
CZ22065U1 (cs)	2011-04-07
SK500482011U1 (en)	2011-07-06
LV14567A (lv)	2012-09-20
BG1474U1 (bg)	2011-08-31
LV14567B (lv)	2013-01-20

Publication	Publication Date	Title
US6352713B1 (en)	2002-03-05	Nutritional composition
Hisano et al.	2012	Cranberries and lower urinary tract infection prevention
EP2859896B1 (en)	2018-01-31	Pharmaceutical compositions for the treatment of muscular disorders
US11357250B2 (en)	2022-06-14	Treatment and prevention of diabetes and obesity
WO2016043524A1 (ko)	2016-03-24	망고스틴 추출물 또는 알파, 감마 망고스틴을 유효성분으로 포함하는 치주질환 예방 또는 개선용 조성물
US20190015448A1 (en)	2019-01-17	Treatment and Prevention of Bone and Joint Disorders
US20210220301A1 (en)	2021-07-22	Pharmaceutical or Nutritional Combination Comprising Beta-Hydroxy-Betamethylbutyrate
US11213535B2 (en)	2022-01-04	Composition containing phytic acid, magnesium and polyphenols for the treatment or prevention of renal lithiasis
CA3070659A1 (en)	2019-01-31	Composition for use in the prevention and treatment of pathologies of the cardiovascular apparatus
US10064835B2 (en)	2018-09-04	Combination of beta-hydroxy-beta-methylbutyrate, arginine and glutamine for use in treating diabetic ulcers
HK1253062A1 (zh)	2019-06-06	营养补充药物
KR20190058346A (ko)	2019-05-29	Chp(시클로-히스프로)를 포함하는 골 손실 질환의 예방, 개선 또는 치료용 조성물
KR102198708B1 (ko)	2021-01-05	타트체리 추출물을 함유하는 근육 질환의 예방, 개선 또는 치료용, 또는 근 기능 개선용 조성물
US11039636B2 (en)	2021-06-22	Treatment and prevention of bone and joint disorders
KR102849916B1 (ko)	2025-08-25	베로니카 인카나 추출물을 함유한 골관절염 개선용 조성물
US20120087991A1 (en)	2012-04-12	Mucositis prevention supplement and treatment
FR2972328A1 (fr)	2012-09-14	Complement alimentaire augmentant la protection de l'epithelium des voies urinaires basses contre les infections a repetition
EP2685967A1 (en)	2014-01-22	Use of type a2 proanthocyanidins in gastroprotected form for the treatment of acute cystitis induced by fimbriated bacterial forms e
US10856566B2 (en)	2020-12-08	Co-Q10, krill oil and vitamin D
KR20200022660A (ko)	2020-03-04	혼합 추출물을 포함하는 지방간, 고지혈증 또는 비만 예방 또는 치료용 조성물
SK500482011U1 (en)	2011-07-06	Dietary supplement the increasing protection of the epithelium of the lower urinary tract before repeated infections
CN105555289B (zh)	2020-09-08	可可多酚及其在治疗或预防嗜酸性食管炎中的效用
US20220323535A1 (en)	2022-10-13	Health supplement
LT5888B (lt)	2012-12-27	Maisto papildas, gerinantis apatinių šlapimo takų epitelio apsaugą nuo pasikartojančių infekcijų
IT202100010409A1 (it)	2022-10-23	Composizione comprendente un fitocomplesso da melograno e suoi usi