SMT201700520T1 - (r)-pirlindolo e suoi sali farmaceuticamente accettabili per uso in medicina - Google Patents

(r)-pirlindolo e suoi sali farmaceuticamente accettabili per uso in medicina

Info

Publication number
SMT201700520T1
SMT201700520T1 SM20170520T SMT201700520T SMT201700520T1 SM T201700520 T1 SMT201700520 T1 SM T201700520T1 SM 20170520 T SM20170520 T SM 20170520T SM T201700520 T SMT201700520 T SM T201700520T SM T201700520 T1 SMT201700520 T1 SM T201700520T1
Authority
SM
San Marino
Prior art keywords
pirlindole
medicine
pharmaceutically acceptable
acceptable salts
salts
Prior art date
Application number
SM20170520T
Other languages
English (en)
Inventor
Filipe Augusto Eugénio Pardal
Pedroso Pedro Filipe Eufrásio
Pecorelli Susana Marques Almeida
Caixado Carlos Alberto Eufrásio Casimiro
Ana Sofia Da Conceição Lopes
João Carlos Ramos Damil
Original Assignee
Tecnimede Sociedade Tecnico Medicinal S A
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tecnimede Sociedade Tecnico Medicinal S A filed Critical Tecnimede Sociedade Tecnico Medicinal S A
Publication of SMT201700520T1 publication Critical patent/SMT201700520T1/it

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicinal Preparation (AREA)
SM20170520T 2014-05-09 2014-05-09 (r)-pirlindolo e suoi sali farmaceuticamente accettabili per uso in medicina SMT201700520T1 (it)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PCT/PT2014/000028 WO2015171004A1 (en) 2014-05-09 2014-05-09 (r)-pirlindole and its pharmaceutically acceptable salts for use in medicine
EP14726443.6A EP3054950B1 (en) 2014-05-09 2014-05-09 (r)-pirlindole and its pharmaceutically acceptable salts for use in medicine

Publications (1)

Publication Number Publication Date
SMT201700520T1 true SMT201700520T1 (it) 2018-01-11

Family

ID=50819930

Family Applications (1)

Application Number Title Priority Date Filing Date
SM20170520T SMT201700520T1 (it) 2014-05-09 2014-05-09 (r)-pirlindolo e suoi sali farmaceuticamente accettabili per uso in medicina

Country Status (29)

Country Link
US (2) US20170145015A1 (it)
EP (1) EP3054950B1 (it)
JP (1) JP2017514884A (it)
KR (1) KR102232198B1 (it)
CN (1) CN106413714A (it)
AU (1) AU2014393489B2 (it)
CA (1) CA2948596C (it)
CY (1) CY1119522T1 (it)
DK (1) DK3054950T3 (it)
EC (1) ECSP16086232A (it)
ES (1) ES2649491T3 (it)
HR (1) HRP20171650T1 (it)
HU (1) HUE035030T2 (it)
IL (1) IL248854B (it)
LT (1) LT3054950T (it)
MA (1) MA39448B1 (it)
MX (1) MX368735B (it)
NO (1) NO3054950T3 (it)
NZ (1) NZ726131A (it)
PH (1) PH12016502236A1 (it)
PL (1) PL3054950T3 (it)
PT (1) PT3054950T (it)
RS (1) RS56590B1 (it)
RU (1) RU2695607C2 (it)
SI (1) SI3054950T1 (it)
SM (1) SMT201700520T1 (it)
TN (1) TN2016000497A1 (it)
UA (1) UA116499C2 (it)
WO (1) WO2015171004A1 (it)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2988983T3 (es) * 2014-05-09 2024-11-22 Tecnimede Sociedade Tecnico Medicinal S Sales de mandelato de enantiómeros de pirlindol para uso en medicina
SI3054950T1 (sl) 2014-05-09 2017-12-29 Tecnimede-Sociedade Tecnico-Medicinal, S.A. (r)-pirindol in njegove farmacevtsko sprejemljive soli za uporabo v medicini
KR102421013B1 (ko) 2016-05-19 2022-07-14 에스케이바이오팜 주식회사 삼차신경통을 예방 또는 치료하기 위한 카바메이트 화합물의 용도
US12201441B2 (en) * 2018-06-13 2025-01-21 Children's Medical Center Corporation Biomarkers of neuropathic pain

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006504795A (ja) * 2002-10-03 2006-02-09 サイプレス バイオサイエンス, インコーポレイテッド 神経学的障害を処置するための抗うつ剤の投薬量の段階的な漸増ならびに毎日の分割した投薬
KR20050101537A (ko) * 2002-12-24 2005-10-24 뉴로켐 (인터내셔널) 리미티드 베타-아밀로이드 관련 질환의 치료를 위한 치료 제제
KR20060117909A (ko) * 2003-09-15 2006-11-17 벡투라 리미티드 폐 흡입에 의한 조루 치료용 제약학적 조성물
EP1688161A1 (en) * 2004-11-02 2006-08-09 Switch Biotech Aktiengesellschaft Use of pirlindole for the treatment of diseases which are characterized by proliferation of t-lymphocytes and/or hyperproliferation of keratinocytes in particular atopic dermatitis and psoriasis
UA118474C2 (uk) * 2014-05-09 2019-01-25 Текнімеді Сос'Єдаді Текніку-Медісінал С.А. (s)-пірліндол та його фармацевтично прийнятні солі для застосування в медицині
ES2988983T3 (es) * 2014-05-09 2024-11-22 Tecnimede Sociedade Tecnico Medicinal S Sales de mandelato de enantiómeros de pirlindol para uso en medicina
SI3054950T1 (sl) 2014-05-09 2017-12-29 Tecnimede-Sociedade Tecnico-Medicinal, S.A. (r)-pirindol in njegove farmacevtsko sprejemljive soli za uporabo v medicini

Also Published As

Publication number Publication date
HUE035030T2 (en) 2018-05-02
CA2948596A1 (en) 2015-11-12
US20170145015A1 (en) 2017-05-25
WO2015171004A1 (en) 2015-11-12
PL3054950T3 (pl) 2018-02-28
MX2016014701A (es) 2017-05-23
IL248854B (en) 2020-05-31
PH12016502236A1 (en) 2017-02-06
ES2649491T3 (es) 2018-01-12
CY1119522T1 (el) 2018-03-07
DK3054950T3 (en) 2017-11-06
RS56590B1 (sr) 2018-02-28
NZ726131A (en) 2018-12-21
NO3054950T3 (it) 2017-12-30
CN106413714A (zh) 2017-02-15
MA39448B1 (fr) 2019-12-31
AU2014393489A1 (en) 2016-11-24
RU2016148182A3 (it) 2018-06-13
KR20170003567A (ko) 2017-01-09
CA2948596C (en) 2021-06-08
UA116499C2 (uk) 2018-03-26
MX368735B (es) 2019-10-14
SI3054950T1 (sl) 2017-12-29
ECSP16086232A (es) 2017-02-24
EP3054950A1 (en) 2016-08-17
AU2014393489B2 (en) 2020-01-02
EP3054950B1 (en) 2017-08-02
US10533012B2 (en) 2020-01-14
KR102232198B1 (ko) 2021-03-26
LT3054950T (lt) 2017-11-27
RU2016148182A (ru) 2018-06-13
PT3054950T (pt) 2017-11-29
US20180111944A1 (en) 2018-04-26
RU2695607C2 (ru) 2019-07-24
JP2017514884A (ja) 2017-06-08
MA39448A1 (fr) 2018-08-31
IL248854A0 (en) 2017-01-31
TN2016000497A1 (en) 2018-04-04
HRP20171650T1 (hr) 2017-12-15

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