SMT202000398T1 - Benzazepine fuse per il trattamento della balbuzie - Google Patents

Benzazepine fuse per il trattamento della balbuzie

Info

Publication number: SMT202000398T1
Authority: SM; San Marino
Prior art keywords: stuttering; treatment; fused benzazepines; benzazepines; fused
Prior art date: 2013-10-18

Application number

SM20200398T

Other languages

English (en)

Inventor

Richard E Chipkin

Original Assignee

Emalex Biosciences Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2013-10-18

Filing date

2014-10-17

Publication date

2020-09-10

2014-10-17 Application filed by Emalex Biosciences Inc filed Critical Emalex Biosciences Inc

2020-09-10 Publication of SMT202000398T1 publication Critical patent/SMT202000398T1/it

Links

208000003028 Stuttering Diseases 0.000 title 1
150000008038 benzoazepines Chemical class 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Epidemiology (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Neurosurgery (AREA)
Nutrition Science (AREA)
Physiology (AREA)
Pain & Pain Management (AREA)
Psychiatry (AREA)
Psychology (AREA)
Orthopedic Medicine & Surgery (AREA)
Physical Education & Sports Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

SM20200398T 2013-10-18 2014-10-17 Benzazepine fuse per il trattamento della balbuzie SMT202000398T1 (it)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US201361892841P	2013-10-18	2013-10-18
PCT/US2014/061080 WO2015058053A1 (en)	2013-10-18	2014-10-17	Fused benzazepines for treatment of stuttering
EP14854586.6A EP3057595B1 (en)	2013-10-18	2014-10-17	Fused benzazepines for treatment of stuttering

Publications (1)

Publication Number	Publication Date
SMT202000398T1 true SMT202000398T1 (it)	2020-09-10

Family

ID=52828726

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SM20200398T SMT202000398T1 (it)	2013-10-18	2014-10-17	Benzazepine fuse per il trattamento della balbuzie

Country Status (19)

Country	Link
US (1)	US9949983B2 (it)
EP (1)	EP3057595B1 (it)
JP (3)	JP2016533374A (it)
AU (1)	AU2014337140B2 (it)
CA (1)	CA2927915C (it)
CY (1)	CY1123121T1 (it)
DK (1)	DK3057595T3 (it)
ES (1)	ES2805448T3 (it)
HR (1)	HRP20201152T1 (it)
HU (1)	HUE049848T2 (it)
IL (1)	IL245155B (it)
LT (1)	LT3057595T (it)
MX (1)	MX370612B (it)
PL (1)	PL3057595T3 (it)
PT (1)	PT3057595T (it)
RS (1)	RS60556B1 (it)
SI (1)	SI3057595T1 (it)
SM (1)	SMT202000398T1 (it)
WO (1)	WO2015058053A1 (it)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
PL2872145T3 (pl)	2012-07-12	2022-06-20	Emalex Biosciences, Inc.	Połączone benzazepiny w leczeniu zespołu tourette’a
EP3628316A4 (en)	2017-03-30	2021-04-14	Penello Temporão, José Eduardo	MULTI-VITAMIN COMPOSITION TO IMPROVE VERB FLUIDITY AND REDUCE SYMPTOMS OF PERFORMANCE ANXIETY AND ITS PREPARATION PROCESS
RU2019143572A (ru) *	2017-05-25	2021-06-25	Глитек Ллс.	Композиции для лечения посттравматического стрессового расстройства
US10786495B2 (en) *	2017-10-10	2020-09-29	The Regents Of The University Of California	Vesicular monoamine transporter 2 inhibitors for treating stuttering
US20210393621A1 (en)	2018-10-26	2021-12-23	The Research Foundation For The State University Of New York	Combination serotonin specific reuptake inhibitor and serotonin 1a receptor partial agonist for reducing l-dopa-induced dyskinesia
EP3972573A4 (en) *	2019-05-23	2023-07-12	India Globalization Capital, Inc.	COMPOSITIONS AND METHODS OF USING CANNABINOIDS TO TREAT STAMMING/STOMMING AND SYMPTOMS OF TOURETTE SYNDROME
US12594281B2 (en)	2024-03-15	2026-04-07	Emalex Biosciences, Inc.	Pharmaceutical dosage forms and methods of use
WO2025194153A1 (en)	2024-03-15	2025-09-18	Emalex Biosciences, Inc.	Pharmaceutical dosage forms and methods of use

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4477378A (en)	1980-02-05	1984-10-16	Schering Corp.	Esters of substituted 8-hydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepines
US4973586A (en)	1986-01-16	1990-11-27	Schering Corporation	Fused benzazepines, compositions of, and medical use thereof
US5302716A (en)	1986-01-16	1994-04-12	Schering Corporation	Fused benzazepines
BE1005064A4 (nl)	1991-07-03	1993-04-06	Asm Fico Tooling	Buiginrichting.
GB9127306D0 (en)	1991-12-23	1992-02-19	Boots Co Plc	Therapeutic agents
WO1995025102A1 (en)	1994-03-16	1995-09-21	Novo Nordisk A/S	Acid addition salts of 2,3,4,5-tetrahydro-1h-3-benzazepine compounds
KR20010031470A (ko) *	1997-10-28	2001-04-16	둘락 노먼 씨.	포유동물의 갈망을 감소시키는 방법
US6132724A (en) *	1998-04-29	2000-10-17	City Of Hope National Medical Center	Allelic polygene diagnosis of reward deficiency syndrome and treatment
SE9904724D0 (sv) *	1999-12-22	1999-12-22	Carlsson A Research Ab	New modulators of dopamine neurotransmission I
US8518933B2 (en) *	2009-04-23	2013-08-27	Abbvie Inc.	Modulators of 5-HT receptors and methods of use thereof
US20110206782A1 (en) *	2010-02-24	2011-08-25	Auspex Pharmaceuticals, Inc.	Piperidine modulators of dopamine receptor
WO2012033874A1 (en)	2010-09-10	2012-03-15	Chipkin Richard E	Method of treating compulsive self-injurious behaviors
PL2872145T3 (pl)	2012-07-12	2022-06-20	Emalex Biosciences, Inc.	Połączone benzazepiny w leczeniu zespołu tourette’a

2014
- 2014-10-17 LT LTEP14854586.6T patent/LT3057595T/lt unknown
- 2014-10-17 HR HRP20201152TT patent/HRP20201152T1/hr unknown
- 2014-10-17 SI SI201431621T patent/SI3057595T1/sl unknown
- 2014-10-17 AU AU2014337140A patent/AU2014337140B2/en active Active
- 2014-10-17 HU HUE14854586A patent/HUE049848T2/hu unknown
- 2014-10-17 JP JP2016524108A patent/JP2016533374A/ja not_active Withdrawn
- 2014-10-17 PL PL14854586T patent/PL3057595T3/pl unknown
- 2014-10-17 RS RS20200880A patent/RS60556B1/sr unknown
- 2014-10-17 WO PCT/US2014/061080 patent/WO2015058053A1/en not_active Ceased
- 2014-10-17 DK DK14854586.6T patent/DK3057595T3/da active
- 2014-10-17 CA CA2927915A patent/CA2927915C/en active Active
- 2014-10-17 ES ES14854586T patent/ES2805448T3/es active Active
- 2014-10-17 PT PT148545866T patent/PT3057595T/pt unknown
- 2014-10-17 MX MX2016005030A patent/MX370612B/es active IP Right Grant
- 2014-10-17 EP EP14854586.6A patent/EP3057595B1/en active Active
- 2014-10-17 US US15/030,271 patent/US9949983B2/en active Active
- 2014-10-17 SM SM20200398T patent/SMT202000398T1/it unknown
2016
- 2016-04-17 IL IL245155A patent/IL245155B/en active IP Right Grant
2019
- 2019-06-13 JP JP2019110259A patent/JP7245509B2/ja active Active
2020
- 2020-07-10 CY CY20201100641T patent/CY1123121T1/el unknown
2021
- 2021-03-01 JP JP2021031859A patent/JP2021080288A/ja active Pending

Also Published As

Publication number	Publication date
LT3057595T (lt)	2020-08-10
IL245155B (en)	2020-07-30
MX370612B (es)	2019-12-18
WO2015058053A1 (en)	2015-04-23
JP2019147843A (ja)	2019-09-05
IL245155A0 (en)	2016-06-30
EP3057595B1 (en)	2020-04-29
SI3057595T1 (sl)	2020-09-30
JP2021080288A (ja)	2021-05-27
NZ719103A (en)	2021-05-28
HRP20201152T1 (hr)	2020-10-30
US9949983B2 (en)	2018-04-24
ES2805448T3 (es)	2021-02-12
US20160271141A1 (en)	2016-09-22
RS60556B1 (sr)	2020-08-31
JP7245509B2 (ja)	2023-03-24
CA2927915C (en)	2021-10-26
PL3057595T3 (pl)	2021-03-08
EP3057595A1 (en)	2016-08-24
DK3057595T3 (da)	2020-08-10
MX2016005030A (es)	2017-01-23
CA2927915A1 (en)	2015-04-23
JP2016533374A (ja)	2016-10-27
HUE049848T2 (hu)	2020-11-30
EP3057595A4 (en)	2017-06-07
CY1123121T1 (el)	2021-10-29
PT3057595T (pt)	2020-07-31
AU2014337140A1 (en)	2016-05-12
AU2014337140B2 (en)	2020-01-30

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IL245155A0 (en)	2016-06-30	Benzazepines are combined for the treatment of stuttering
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