SMT202000620T1 - Distribuzione di proteine basata su batteri - Google Patents
Distribuzione di proteine basata su batteriInfo
- Publication number
- SMT202000620T1 SMT202000620T1 SM20200620T SMT202000620T SMT202000620T1 SM T202000620 T1 SMT202000620 T1 SM T202000620T1 SM 20200620 T SM20200620 T SM 20200620T SM T202000620 T SMT202000620 T SM T202000620T SM T202000620 T1 SMT202000620 T1 SM T202000620T1
- Authority
- SM
- San Marino
- Prior art keywords
- bacteria
- based protein
- protein delivery
- delivery
- protein
- Prior art date
Links
- 241000894006 Bacteria Species 0.000 title 1
- 102000004169 proteins and genes Human genes 0.000 title 1
- 108090000623 proteins and genes Proteins 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/70—Vectors or expression systems specially adapted for E. coli
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/036—Fusion polypeptide containing a localisation/targetting motif targeting to the medium outside of the cell, e.g. type III secretion
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/33—Fusion polypeptide fusions for targeting to specific cell types, e.g. tissue specific targeting, targeting of a bacterial subspecies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/50—Fusion polypeptide containing protease site
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- General Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Enzymes And Modification Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP15195493 | 2015-11-19 | ||
| EP16825704.6A EP3377634B1 (en) | 2015-11-19 | 2016-11-17 | Bacteria-based protein delivery |
| PCT/EP2016/078087 WO2017085235A1 (en) | 2015-11-19 | 2016-11-17 | Bacteria-based protein delivery |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SMT202000620T1 true SMT202000620T1 (it) | 2021-01-05 |
Family
ID=54697465
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SM20200620T SMT202000620T1 (it) | 2015-11-19 | 2016-11-17 | Distribuzione di proteine basata su batteri |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US11702663B2 (it) |
| EP (1) | EP3377634B1 (it) |
| JP (1) | JP6937752B2 (it) |
| KR (1) | KR102689434B1 (it) |
| CN (1) | CN108884466B (it) |
| AU (1) | AU2016355975B2 (it) |
| CY (1) | CY1123654T1 (it) |
| DK (1) | DK3377634T3 (it) |
| EA (1) | EA039922B1 (it) |
| ES (1) | ES2830251T3 (it) |
| HR (1) | HRP20201792T1 (it) |
| HU (1) | HUE051184T2 (it) |
| IL (1) | IL259050B2 (it) |
| LT (1) | LT3377634T (it) |
| PL (1) | PL3377634T3 (it) |
| PT (1) | PT3377634T (it) |
| RS (1) | RS61046B1 (it) |
| SG (1) | SG11201803642WA (it) |
| SI (1) | SI3377634T1 (it) |
| SM (1) | SMT202000620T1 (it) |
| WO (1) | WO2017085235A1 (it) |
| ZA (1) | ZA201803901B (it) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2014071182A1 (en) | 2012-11-01 | 2014-05-08 | Massachusetts Institute Of Technology | Directed evolution of synthetic gene cluster |
| CN107001431B (zh) * | 2014-05-21 | 2022-11-01 | 巴塞尔大学 | 基于细菌的蛋白质递送 |
| BR112018000729B1 (pt) | 2015-07-13 | 2023-02-07 | Pivot Bio, Inc | Método de aumento de uma quantidade de nitrogênio atmosférico em uma planta de milho em um campo |
| EA201890868A1 (ru) | 2015-11-19 | 2018-12-28 | Университет Базель | Бактерии с ослабленной вирулентностью для лечения злокачественных солидных опухолей |
| JP6976351B2 (ja) | 2016-12-20 | 2021-12-08 | ウニヴェルズィテート・バーゼルUniversitat Basel | 弱毒化細菌に基づくタンパク質送達 |
| AU2018207204B2 (en) | 2017-01-12 | 2023-11-30 | Pivot Bio, Inc. | Methods and compositions for improving plant traits |
| CN111587287B (zh) | 2017-10-25 | 2025-02-18 | 皮沃特生物股份有限公司 | 用于改良固氮的工程微生物的方法和组合物 |
| BR112020026676A2 (pt) | 2018-06-27 | 2021-08-03 | Pivot Bio, Inc. | remodelação microbiana guiada, uma plataforma para a melhoria racional de espécies microbianas para agricultura |
| WO2020190363A1 (en) | 2019-03-19 | 2020-09-24 | Massachusetts Institute Of Technology | Control of nitrogen fixation in rhizobia that associate with cereals |
| KR20220004047A (ko) | 2019-04-25 | 2022-01-11 | 피벗 바이오, 인크. | 화학적 돌연변이유발에 의해 생성된 암모늄-배출 돌연변이체 라이브러리를 단리하고 특징 분석하기 위한 고 처리량 방법 |
| US12643837B2 (en) | 2020-05-01 | 2026-06-02 | Pivot Bio, Inc. | Modified bacterial strains for improved fixation of nitrogen |
| WO2022087856A1 (zh) * | 2020-10-26 | 2022-05-05 | 南京吉芮康生物科技研究院有限公司 | 一种减毒沙门氏菌分泌表达rbd结构域蛋白的新型冠状病毒疫苗抗原递呈系统及其应用 |
| IL302334A (en) * | 2020-10-27 | 2023-06-01 | T3 Pharmaceuticals Ag | Providing bacteria-based protein |
| PH12023552423A1 (en) * | 2021-03-25 | 2024-02-19 | T3 Pharmaceuticals Ag | Pharmaceutical combinations for treating cancer |
| EP4314036A1 (en) * | 2021-03-25 | 2024-02-07 | T3 Pharmaceuticals AG | Pharmaceutical combinations for treating cancer |
| KR102873285B1 (ko) * | 2022-01-03 | 2025-10-20 | 고려대학교 세종산학협력단 | 스캐폴드 기반의 다중항원을 포함하는 코로나바이러스 감염병 예방 또는 치료용 항원 조성물 |
| CN117362451B (zh) * | 2023-12-04 | 2024-03-08 | 北京质肽生物医药科技有限公司 | 一种包含tev蛋白酶的融合蛋白、制备方法及其应用 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5965381A (en) | 1998-03-06 | 1999-10-12 | Ludwig Institute For Cancer Research | Delivery of proteins into eukaryotic cells with recombinant yersinia |
| US6596509B1 (en) * | 1998-07-10 | 2003-07-22 | Cornell Research Foundation, Inc. | Recombinant constructs and systems for secretion of proteins via type III secretion systems |
| US20020160502A1 (en) | 2000-09-26 | 2002-10-31 | Roger Williams Hospital | Recombinant BCG vaccines for the prevention and treatment of cancer |
| AU2002312778A1 (en) * | 2001-03-26 | 2002-10-08 | Universite Catholique De Louvain | Type iii bacterial strains for use in medicine |
| FR2862312B1 (fr) * | 2003-11-13 | 2006-02-17 | Univ Grenoble 1 | Outil de transfert et de production de proteines mettant en oeuvre le systeme de secretion de type iii de pseudomonas |
| EP1661912A1 (en) * | 2004-11-29 | 2006-05-31 | Xigen S.A. | Fusion protein comprising a BH3-domain of a BH3-only protein |
| US8357373B2 (en) | 2005-10-04 | 2013-01-22 | Ludwig Institute For Cancer Research | Methods for stimulating an immune response using bacterial antigen delivery system |
| WO2008019183A2 (en) | 2006-05-18 | 2008-02-14 | The Regents Of The University Of California | Biopolymer and protein production using type iii secretion systems of gram negative bacteria |
| TW200819540A (en) | 2006-07-11 | 2008-05-01 | Genelux Corp | Methods and compositions for detection of microorganisms and cells and treatment of diseases and disorders |
| EP2268313A2 (en) | 2008-03-17 | 2011-01-05 | Universitätsklinikum Münster | Yopm as delivery vehicle for cargo molecules and as biological therapeutic for immunomodulation of inflammatory reactions |
| US8524220B1 (en) * | 2010-02-09 | 2013-09-03 | David Gordon Bermudes | Protease inhibitor: protease sensitivity expression system composition and methods improving the therapeutic activity and specificity of proteins delivered by bacteria |
| JP6936934B2 (ja) * | 2013-09-24 | 2021-09-22 | メディシナ セラピューティクス インコーポレイテッド | インターロイキン−４受容体結合融合タンパク質及びその使用 |
| US10143743B2 (en) | 2013-11-18 | 2018-12-04 | Yale University | Non-replicating bacterial nanoparticle delivery system and methods of use |
| CN107001431B (zh) * | 2014-05-21 | 2022-11-01 | 巴塞尔大学 | 基于细菌的蛋白质递送 |
| EA201890868A1 (ru) | 2015-11-19 | 2018-12-28 | Университет Базель | Бактерии с ослабленной вирулентностью для лечения злокачественных солидных опухолей |
| JP6976351B2 (ja) | 2016-12-20 | 2021-12-08 | ウニヴェルズィテート・バーゼルUniversitat Basel | 弱毒化細菌に基づくタンパク質送達 |
-
2016
- 2016-11-17 SM SM20200620T patent/SMT202000620T1/it unknown
- 2016-11-17 WO PCT/EP2016/078087 patent/WO2017085235A1/en not_active Ceased
- 2016-11-17 ES ES16825704T patent/ES2830251T3/es active Active
- 2016-11-17 SI SI201630974T patent/SI3377634T1/sl unknown
- 2016-11-17 KR KR1020187016715A patent/KR102689434B1/ko active Active
- 2016-11-17 DK DK16825704.6T patent/DK3377634T3/da active
- 2016-11-17 PT PT168257046T patent/PT3377634T/pt unknown
- 2016-11-17 CN CN201680079453.5A patent/CN108884466B/zh active Active
- 2016-11-17 IL IL259050A patent/IL259050B2/en unknown
- 2016-11-17 EA EA201890914A patent/EA039922B1/ru unknown
- 2016-11-17 HU HUE16825704A patent/HUE051184T2/hu unknown
- 2016-11-17 AU AU2016355975A patent/AU2016355975B2/en active Active
- 2016-11-17 US US15/773,526 patent/US11702663B2/en active Active
- 2016-11-17 SG SG11201803642WA patent/SG11201803642WA/en unknown
- 2016-11-17 HR HRP20201792TT patent/HRP20201792T1/hr unknown
- 2016-11-17 LT LTEP16825704.6T patent/LT3377634T/lt unknown
- 2016-11-17 JP JP2018526175A patent/JP6937752B2/ja active Active
- 2016-11-17 RS RS20201344A patent/RS61046B1/sr unknown
- 2016-11-17 EP EP16825704.6A patent/EP3377634B1/en active Active
- 2016-11-17 PL PL16825704T patent/PL3377634T3/pl unknown
-
2018
- 2018-06-12 ZA ZA2018/03901A patent/ZA201803901B/en unknown
-
2020
- 2020-11-05 CY CY20201101044T patent/CY1123654T1/el unknown
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