SU1017172A3 - Способ получени производных димера Винка или их солей - Google Patents

Способ получени производных димера Винка или их солей Download PDF

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Publication number
SU1017172A3
SU1017172A3 SU813259901A SU3259901A SU1017172A3 SU 1017172 A3 SU1017172 A3 SU 1017172A3 SU 813259901 A SU813259901 A SU 813259901A SU 3259901 A SU3259901 A SU 3259901A SU 1017172 A3 SU1017172 A3 SU 1017172A3
Authority
SU
USSR - Soviet Union
Prior art keywords
salts
vlb
compound
wink
formula
Prior art date
Application number
SU813259901A
Other languages
English (en)
Russian (ru)
Inventor
Коринн Миллер Джин
Эдвард Гутовски Джеральд
Original Assignee
Эли Лилли Энд Компани (Фирма)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Эли Лилли Энд Компани (Фирма) filed Critical Эли Лилли Энд Компани (Фирма)
Application granted granted Critical
Publication of SU1017172A3 publication Critical patent/SU1017172A3/ru

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • C07D519/02—Ergot alkaloids of the cyclic peptide type
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • C07D519/04—Dimeric indole alkaloids, e.g. vincaleucoblastine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
SU813259901A 1980-03-20 1981-03-19 Способ получени производных димера Винка или их солей SU1017172A3 (ru)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/132,246 US4357334A (en) 1980-03-20 1980-03-20 Use of VLB 3-(2-chloroethyl) carboxamide in treating neoplasms

Publications (1)

Publication Number Publication Date
SU1017172A3 true SU1017172A3 (ru) 1983-05-07

Family

ID=22453135

Family Applications (2)

Application Number Title Priority Date Filing Date
SU813259901A SU1017172A3 (ru) 1980-03-20 1981-03-19 Способ получени производных димера Винка или их солей
SU823430670A SU1200851A3 (ru) 1980-03-20 1982-05-04 Способ получени димера Винка или его фармацевтически приемлемых солей

Family Applications After (1)

Application Number Title Priority Date Filing Date
SU823430670A SU1200851A3 (ru) 1980-03-20 1982-05-04 Способ получени димера Винка или его фармацевтически приемлемых солей

Country Status (28)

Country Link
US (1) US4357334A (de)
EP (1) EP0036762B1 (de)
JP (1) JPS56145293A (de)
KR (1) KR840002146B1 (de)
AR (1) AR228863A1 (de)
AT (1) ATE9761T1 (de)
AU (1) AU539564B2 (de)
BG (1) BG36200A3 (de)
CA (1) CA1159055A (de)
DD (1) DD157558A5 (de)
DE (1) DE3166544D1 (de)
DK (1) DK124281A (de)
EG (1) EG15247A (de)
ES (2) ES8206538A1 (de)
FI (1) FI810856A7 (de)
GB (1) GB2072184B (de)
GR (1) GR73870B (de)
HU (1) HU185247B (de)
IE (1) IE51034B1 (de)
IL (1) IL62378A (de)
NZ (1) NZ196511A (de)
PH (1) PH16213A (de)
PL (1) PL230226A1 (de)
PT (1) PT72695B (de)
RO (2) RO85813B (de)
SU (2) SU1017172A3 (de)
YU (1) YU66281A (de)
ZA (1) ZA811733B (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0124502B1 (de) * 1983-04-29 1991-06-12 OMNICHEM Société anonyme Konjugierte Vinblastin-Verbindungen und ihre Derivate, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zusammensetzungen
HUT76925A (hu) * 1995-04-04 1998-01-28 MTA Enzimológiai Intézet Bisz-indol-származékok, eljárás előállításukra és az azokat tartalmazó gyógyszerkészítmények

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR204004A1 (es) 1973-04-02 1975-11-12 Lilly Co Eli Procedimientos para preparar derivados de vinblastina leurosidina y leurocristina
IL48685A (en) 1975-01-09 1980-03-31 Lilly Co Eli Amides of vincadioline and vinblastine
GR69783B (de) 1976-09-08 1982-07-07 Lilly Co Eli
US4096148A (en) * 1976-12-06 1978-06-20 Eli Lilly And Company Oxazolidinedione derivatives of Vinca alkaloids
USRE30561E (en) 1976-12-06 1981-03-31 Eli Lilly And Company Vinca alkaloid intermediates
US4160767A (en) * 1976-12-06 1979-07-10 Eli Lilly And Company Vinca alkaloid intermediates
US4191688A (en) * 1977-08-08 1980-03-04 Eli Lilly And Company Amides of leurosine, leuroformine, desacetylleurosine and desacetylleuroformine
US4203898A (en) * 1977-08-29 1980-05-20 Eli Lilly And Company Amide derivatives of VLB, leurosidine, leurocristine and related dimeric alkaloids

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
1. Патент СССР по эа &ке №2429453/04, кл. С 07 D 519/04, . 1976. *

Also Published As

Publication number Publication date
RO85813B (ro) 1984-11-30
ES500536A0 (es) 1982-08-16
ATE9761T1 (de) 1984-10-15
PT72695B (en) 1982-03-24
AU539564B2 (en) 1984-10-04
NZ196511A (en) 1983-09-30
YU66281A (en) 1983-10-31
PH16213A (en) 1983-08-05
EP0036762B1 (de) 1984-10-10
IL62378A0 (en) 1981-05-20
HU185247B (en) 1984-12-28
KR840002146B1 (ko) 1984-11-23
IE810609L (en) 1981-09-20
ES8206538A1 (es) 1982-08-16
RO82171B (ro) 1983-06-30
RO85813A (ro) 1984-11-25
DD157558A5 (de) 1982-11-17
FI810856L (fi) 1981-09-21
EP0036762A3 (en) 1981-10-07
EG15247A (en) 1986-03-31
PT72695A (en) 1981-04-01
GB2072184A (en) 1981-09-30
KR830005248A (ko) 1983-08-03
PL230226A1 (de) 1982-03-15
ZA811733B (en) 1982-10-27
US4357334A (en) 1982-11-02
AU6858181A (en) 1981-09-24
GB2072184B (en) 1984-01-11
DE3166544D1 (en) 1984-11-15
DK124281A (da) 1981-09-21
CA1159055A (en) 1983-12-20
GR73870B (de) 1984-05-09
RO82171A (ro) 1983-07-07
FI810856A7 (fi) 1981-09-21
ES8302009A1 (es) 1982-12-16
IL62378A (en) 1984-03-30
ES509581A0 (es) 1982-12-16
BG36200A3 (bg) 1984-09-14
IE51034B1 (en) 1986-09-17
EP0036762A2 (de) 1981-09-30
SU1200851A3 (ru) 1985-12-23
JPS56145293A (en) 1981-11-11
AR228863A1 (es) 1983-04-29

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