SU1114392A1 - Poultry growth stimulant - Google Patents

Abstract

The use of 3-deoxy-2-C-hydroxymethyl-calcium pentonate of the formula CH.OHCHOHCH1CHOH(),2 as a growth stimulant for birds.

Description

111143 The invention relates to agriculture, in particular to fattening farm animals and birds using growth stimulants. A commonly used means for stimulating animal growth is a quinoxaline derivative CiD. However, quinoxaline derivatives have a carcinogenic effect and are hazardous to the health of animals and humans. Known are stimulants for increasing the weight of farm animals and birds that contain perchloric acid salts, the use of which in fattening cattle provides an additional 12% weight gain while saving feed compared to the control groups C21. The disadvantage of these growth stimulants is that in pure form and especially in a mixture in certain proportions with organic products they are explosive and fire hazardous, and when diluted with water they are expensive to transport. Currently, known biostimulants such as glycocopherol, ethoxyquin or their mixture in certain ratios, diludin (ethidine), etc. are used to stimulate animal growth. They increase the weight of chickens by 10%. Adding dry fish broth concentrate in an amount of 0.65-1% to the chicken diet is accompanied by an increase in their live weight by 13-14% C31. The disadvantage of known biostimulants is their high cost, which reduces the effectiveness of their use in animal husbandry. The aim of the invention is to find a new agent that is non-toxic, stable during storage, increases the weight gain of birds and reduces feed costs per unit of their gain.

This goal is achieved by using calcium 3-deoxy-2-C-hydroxymethyl-B-pentonate (DGP-3) of the general formula CH OHCHOHCHg CHOH (CHjOH) C02Ca,/j as an additive in feed mixtures.

Previously, the substance was used only as a chemical reagent C41.

The preparation remains unchanged during storage of feed.

The use of the drug makes it possible to obtain weight gain at eco100,0100,0

As a result, the feed nomy is somewhat higher than when using known stimulants. Example. For 90 days, 250 Leghorn chickens from the age of 3 days were fattened, which were divided into two groups - 125 heads in each and placed in battery cages of the KBN type. The compound feed was distributed manually, watering was done with running water. After 30 days from the beginning of the experiment, the livestock was transferred to another poultry house and also placed in groups in battery cages for the second age, where lighting and ventilation meet the technical requirements for this poultry house. For experimental purposes, two batches of compound feed of the following composition were produced according to the recipe PK-2-3 and PK-3-2 (Table 1). Table 1

E11143924

In order to determine the impact of the proposed feeding, the results are presented

effect of the drug on the animal's body is shown in Table 3.

experiments were conducted on feed and poultry. As can be seen from Table 3, the use of

the chickens of the drug, makes it possible, under equal conditions,

The experimental group's feed was supplemented with the following conditions: feeding and keeping of birds

l if the drug in the amount of 10 mg will receive 18.6Z more growth

head per day. .in live weight. In this case, the feed consumption

The chemical composition of compound feed decreases per 1 kg of weight gain.

is given in Table 2.

Table 2 The following parameters were studied: change in live weight by individual weighing at the beginning, end and after 15 days of the experiment; feed consumption per unit of weight gain, survival of young birds and the efficiency of using the preparation, as well as the condition of the internal organs of the experimental chickens at the end of the experiment, for which 3 heads were slaughtered from each group.

by 2.5 g per day. It should also be noted that the survival rate of chickens increases by 9.6%.

When studying the condition of some organs, such as the liver, spleen,

heart, lungs, stomach, it was found that 15 the test drug does not negatively affect their development.

Table 3

Indicator

A group of chickens

I

Test I Experienced 

Live weight of one chicken on average, g

at the beginning

experience 54,6610,98 57,t4tO,6

at the end

845,,6 985,15tlO,3 exp

Total weight gain per chicken928,0

791.0 lenok, g

Average daily weight gain of one chicken, «°«trolyu 100 . Consumption of compound feed per day per 1 gopov on average, G 42.8

Continuation of table 3

:zi:iz::z::

QZ

3.87 4.88

0.70 0.75

The proposed compound 3-deoxy-2-C-hydroxymethyl-T)-calcium pectonate has a number of advantages over known stimulants, such as calcium peroxide: the preparation is non-toxic, remains unchanged, makes it possible to obtain greater live weight gain with increased survivability and reduced feed costs per 1 kg of weight gain, the proposed stimulant also has advantages over other stimulants (see Table 4).

Table 4

The proposed stimulus Thus, the proposed drug is not toxic to animals and birds. In experiments on. studying the acute toxicity of the drug

In mice, with intraperitoneal (1000 mg/kg) and oral (4 g/kg) administration, no lethal outcomes or disturbances in the general condition of the animal were detected.