SU1281988A1 - Электрохимический датчик дл измерени концентрации глюкозы - Google Patents
Электрохимический датчик дл измерени концентрации глюкозы Download PDFInfo
- Publication number
- SU1281988A1 SU1281988A1 SU843710780A SU3710780A SU1281988A1 SU 1281988 A1 SU1281988 A1 SU 1281988A1 SU 843710780 A SU843710780 A SU 843710780A SU 3710780 A SU3710780 A SU 3710780A SU 1281988 A1 SU1281988 A1 SU 1281988A1
- Authority
- SU
- USSR - Soviet Union
- Prior art keywords
- electrode
- working chamber
- glucose concentration
- measuring glucose
- electrochemical transducer
- Prior art date
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- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 title claims description 5
- 239000008103 glucose Substances 0.000 title claims description 5
- 238000005259 measurement Methods 0.000 claims description 3
- 230000035945 sensitivity Effects 0.000 claims description 3
- RTAQQCXQSZGOHL-UHFFFAOYSA-N Titanium Chemical compound [Ti] RTAQQCXQSZGOHL-UHFFFAOYSA-N 0.000 claims description 2
- 239000003792 electrolyte Substances 0.000 claims description 2
- 239000012528 membrane Substances 0.000 claims description 2
- 239000010936 titanium Substances 0.000 claims description 2
- 229910052719 titanium Inorganic materials 0.000 claims description 2
- 239000012911 assay medium Substances 0.000 claims 1
- 238000007599 discharging Methods 0.000 claims 1
- 239000000463 material Substances 0.000 claims 1
- 229910052751 metal Inorganic materials 0.000 claims 1
- 239000002184 metal Substances 0.000 claims 1
- 239000010953 base metal Substances 0.000 description 1
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- Investigating Or Analysing Biological Materials (AREA)
Description
-f
2
/ . /
ю ас
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Изобретение относитс к аналити- ческому приборостроению и может быть использовано в биохимии дл определени глюкозы.
Целью изобретени вл етс повышение чувствительности и точности измерений в широком диапазоне измер емых концентраций.
На чертеже представлена схема электрохимического датчика дл определени глюкозы.
Электрохимический датчик состоит из корпуса 1 с входным 2 и вькод- ным 3 каналами дл подвода электро- лита и отверстием 4 дл подачи исследуемой пробы, внутренней рабочей камеры 5 с размещенным в ее стенке измерительным электродом 6, снабженным селективной мембраной 7, электродом 8 сравнени , а в днище рабочей камеры установлен дополнительный вспомогательный электрод 9, выполненный из неблагородного металла, например из титана,причем отношение площади активной поверхности рабочего электрода и площади активной поверхности вспомогательного электрода выбрано в пределах 0,12-0,35,
На основе многократных исследований установлены оптимальные размеры электродов, т.е. высока чувствительность и точность определений при широком диапазоне концентраций глюко- зы (0-30 мм) показаны при выборе соотношений 0,12-0,34.
В таблице показано, как мен етс точность измерений при выходе за указанные границы.
,06
,12
,24
1
5
10
15
30
1
5
10
15
30
1
5
10
О О О О
о
0,05
0,05
0,05
0,05
0,05
0,1
0,1
0,1
1
5
9,4 2,1 4,9
1,05
5,05 OjO 4,9 8,8
1,1
5,1
0,1
О
О
-0,6 -2,9 -5,1
0,05
0,05
О -0,1
-1.2 0,1 0,1 0.1
О
О
4,0 19,3 17,0
5
1
О
0,6
4 10
2
1
Продолжение таблицы
Claims (2)
1. ЭЛЕКТРОХИМИЧЕСКИЙ ДАТЧИК ДЛЯ ИЗМЕРЕНИЯ КОНЦЕНТРАЦИИ ГЛЮКОЗЫ, содержащий корпус с размещенной в нем рабочей камерой с отверстием для ввода анализируемой пробы, входным и выходным патрубками соответственно для подвода и отвода электролита, измерительным электродом, установленным в стенке рабочей камеры, который снабжен селективной мембраной и электродом сравнения, отличающийся тем, что, с целью повышения чувствительности и точности измерений в широком диапазоне измеряемых концентраций, в днище рабочей камеры дополнительно установлены вспомогательный электрод из металла, инертного по отношению к анализируемой среде, причем отношение площадей активных поверхностей рабочего и вспомогательного электродов выбрано в пределах 0,12-0,35.
2. Датчик поп.1, отличающийся тем, что в качестве материала вспомогательного электрода используют титан.
SU„, 1281988 А1
1 -12.
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SU843710780A SU1281988A1 (ru) | 1984-03-15 | 1984-03-15 | Электрохимический датчик дл измерени концентрации глюкозы |
| LTRP1164A LT2322B (lt) | 1984-03-15 | 1993-09-27 | Elektrocheminis daviklis gliukozes koncentracijai matuoti |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SU843710780A SU1281988A1 (ru) | 1984-03-15 | 1984-03-15 | Электрохимический датчик дл измерени концентрации глюкозы |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SU1281988A1 true SU1281988A1 (ru) | 1987-01-07 |
Family
ID=21107373
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SU843710780A SU1281988A1 (ru) | 1984-03-15 | 1984-03-15 | Электрохимический датчик дл измерени концентрации глюкозы |
Country Status (1)
| Country | Link |
|---|---|
| SU (1) | SU1281988A1 (ru) |
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| US6484046B1 (en) | 1998-03-04 | 2002-11-19 | Therasense, Inc. | Electrochemical analyte sensor |
| US6514718B2 (en) | 1991-03-04 | 2003-02-04 | Therasense, Inc. | Subcutaneous glucose electrode |
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| US6591125B1 (en) | 2000-06-27 | 2003-07-08 | Therasense, Inc. | Small volume in vitro analyte sensor with diffusible or non-leachable redox mediator |
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1984
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