SU1627087A3 - Способ получени диастереомера N- @ 4-[2-(2-амино-4-гидрокси-5,6,7,8-тетрагидропиридо[2,3- @ ]пиримидин-6-ил)этил]бензоил @ -L-глутаминовой кислоты со значением [ @ ] @ -21,06 @ или диастереомера N- @ 4-[2-(2-амино-4-гидрокси-5,6,7,8-тетрагидропиридо[2,3- @ ]пиримидин-6-ил)этил]бензоил @ -L-глутаминовой кислоты со значением [ @ ] @ +31,09 @ или их фармацевтически приемлемых солей с основанием - Google Patents

Способ получени диастереомера N- @ 4-[2-(2-амино-4-гидрокси-5,6,7,8-тетрагидропиридо[2,3- @ ]пиримидин-6-ил)этил]бензоил @ -L-глутаминовой кислоты со значением [ @ ] @ -21,06 @ или диастереомера N- @ 4-[2-(2-амино-4-гидрокси-5,6,7,8-тетрагидропиридо[2,3- @ ]пиримидин-6-ил)этил]бензоил @ -L-глутаминовой кислоты со значением [ @ ] @ +31,09 @ или их фармацевтически приемлемых солей с основанием Download PDF

Info

Publication number: SU1627087A3
Authority: SU; USSR - Soviet Union
Prior art keywords: hydroxy; diastereomer; amino; glutamic acid; benzoyl
Prior art date: 1986-06-06

Application number

SU874202677A

Other languages

English (en)

Russian (ru)

Inventor

С.Тейлор Эдуард

Питер Бердсли Джордж

Ших Чуан

Р.Флетчер Стивен

Original Assignee

Дзе Трастиз Оф Принстон Юниверсити (Фирма)

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1986-06-06

Filing date

1987-06-05

Publication date

1991-02-07

1987-06-05 Application filed by Дзе Трастиз Оф Принстон Юниверсити (Фирма) filed Critical Дзе Трастиз Оф Принстон Юниверсити (Фирма)

1991-02-07 Application granted granted Critical

1991-02-07 Publication of SU1627087A3 publication Critical patent/SU1627087A3/ru

Links

229960002989 glutamic acid Drugs 0.000 title claims description 15
238000000034 method Methods 0.000 title claims description 4
125000006239 protecting group Chemical group 0.000 claims abstract description 8
150000001875 compounds Chemical class 0.000 claims abstract description 6
239000004220 glutamic acid Substances 0.000 claims description 12
-1 ethyl benzoyl Chemical group 0.000 claims description 10
125000004943 pyrimidin-6-yl group Chemical group N1=CN=CC=C1* 0.000 claims description 10
150000003839 salts Chemical class 0.000 claims description 10
239000002253 acid Substances 0.000 claims description 8
239000002585 base Substances 0.000 claims description 7
125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 claims description 6
125000003236 benzoyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C(*)=O 0.000 claims description 5
229910052799 carbon Inorganic materials 0.000 claims description 5
229910052739 hydrogen Inorganic materials 0.000 claims description 4
WHUUTDBJXJRKMK-UHFFFAOYSA-N Glutamic acid Natural products OC(=O)C(N)CCC(O)=O WHUUTDBJXJRKMK-UHFFFAOYSA-N 0.000 claims description 3
235000013922 glutamic acid Nutrition 0.000 claims description 3
241001465754 Metazoa Species 0.000 claims description 2
125000002252 acyl group Chemical group 0.000 claims description 2
125000004432 carbon atom Chemical group C* 0.000 claims description 2
239000012458 free base Substances 0.000 claims description 2
150000003278 haem Chemical class 0.000 claims description 2
239000001257 hydrogen Substances 0.000 claims description 2
206010028980 Neoplasm Diseases 0.000 claims 1
125000002091 cationic group Chemical group 0.000 claims 1
230000001681 protective effect Effects 0.000 claims 1
238000000926 separation method Methods 0.000 abstract description 2
ZUQBAQVRAURMCL-CVRLYYSRSA-N (2s)-2-[[4-[2-(2-amino-4-oxo-5,6,7,8-tetrahydro-1h-pyrido[2,3-d]pyrimidin-6-yl)ethyl]benzoyl]amino]pentanedioic acid Chemical compound C1NC=2NC(N)=NC(=O)C=2CC1CCC1=CC=C(C(=O)N[C@@H](CCC(O)=O)C(O)=O)C=C1 ZUQBAQVRAURMCL-CVRLYYSRSA-N 0.000 abstract 1
229940034982 antineoplastic agent Drugs 0.000 abstract 1
239000002246 antineoplastic agent Substances 0.000 abstract 1
150000001732 carboxylic acid derivatives Chemical group 0.000 abstract 1
230000003301 hydrolyzing effect Effects 0.000 abstract 1
125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 1
RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 12
OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 description 6
HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 6
LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 5
QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 description 3
239000007787 solid Substances 0.000 description 3
239000000243 solution Substances 0.000 description 3
WHUUTDBJXJRKMK-VKHMYHEASA-N L-glutamic acid Chemical compound OC(=O)[C@@H](N)CCC(O)=O WHUUTDBJXJRKMK-VKHMYHEASA-N 0.000 description 2
241000699670 Mus sp. Species 0.000 description 2
RKOTXQYWCBGZLP-UHFFFAOYSA-N N-[(2,4-difluorophenyl)methyl]-2-ethyl-9-hydroxy-3-methoxy-1,8-dioxospiro[3H-pyrido[1,2-a]pyrazine-4,3'-oxolane]-7-carboxamide Chemical compound CCN1C(OC)C2(CCOC2)N2C=C(C(=O)NCC3=C(F)C=C(F)C=C3)C(=O)C(O)=C2C1=O RKOTXQYWCBGZLP-UHFFFAOYSA-N 0.000 description 2
230000000259 anti-tumor effect Effects 0.000 description 2
MIOPJNTWMNEORI-UHFFFAOYSA-N camphorsulfonic acid Chemical compound C1CC2(CS(O)(=O)=O)C(=O)CC1C2(C)C MIOPJNTWMNEORI-UHFFFAOYSA-N 0.000 description 2
150000001768 cations Chemical group 0.000 description 2
238000004128 high performance liquid chromatography Methods 0.000 description 2
238000002955 isolation Methods 0.000 description 2
239000000203 mixture Substances 0.000 description 2
239000012452 mother liquor Substances 0.000 description 2
230000003287 optical effect Effects 0.000 description 2
239000000047 product Substances 0.000 description 2
239000011541 reaction mixture Substances 0.000 description 2
VWDWKYIASSYTQR-UHFFFAOYSA-N sodium nitrate Chemical compound [Na+].[O-][N+]([O-])=O VWDWKYIASSYTQR-UHFFFAOYSA-N 0.000 description 2
MFEDKMBNKNOUPA-UHFFFAOYSA-N (2-bromo-4,7-dimethyl-3-oxo-7-bicyclo[2.2.1]heptanyl)methanesulfonic acid Chemical compound C1CC2(C)C(=O)C(Br)C1C2(CS(O)(=O)=O)C MFEDKMBNKNOUPA-UHFFFAOYSA-N 0.000 description 1
MIOPJNTWMNEORI-GMSGAONNSA-N (S)-camphorsulfonic acid Chemical compound C1C[C@@]2(CS(O)(=O)=O)C(=O)C[C@@H]1C2(C)C MIOPJNTWMNEORI-GMSGAONNSA-N 0.000 description 1
241001260012 Bursa Species 0.000 description 1
101100135744 Caenorhabditis elegans pch-2 gene Proteins 0.000 description 1
OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 1
206010035226 Plasma cell myeloma Diseases 0.000 description 1
239000007864 aqueous solution Substances 0.000 description 1
125000004429 atom Chemical group 0.000 description 1
125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 description 1
238000000354 decomposition reaction Methods 0.000 description 1
125000004177 diethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 description 1
230000000694 effects Effects 0.000 description 1
239000000839 emulsion Substances 0.000 description 1
238000001704 evaporation Methods 0.000 description 1
230000008020 evaporation Effects 0.000 description 1
238000001914 filtration Methods 0.000 description 1
238000001640 fractional crystallisation Methods 0.000 description 1
208000032839 leukemia Diseases 0.000 description 1
238000004519 manufacturing process Methods 0.000 description 1
239000000463 material Substances 0.000 description 1
201000000050 myeloid neoplasm Diseases 0.000 description 1
PIRWNASAJNPKHT-SHZATDIYSA-N pamp Chemical compound C([C@@H](C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC=1C2=CC=CC=C2NC=1)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCNC(N)=N)C(N)=O)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](C)N)C(C)C)C1=CC=CC=C1 PIRWNASAJNPKHT-SHZATDIYSA-N 0.000 description 1
239000002244 precipitate Substances 0.000 description 1
238000002360 preparation method Methods 0.000 description 1
238000010992 reflux Methods 0.000 description 1
239000004317 sodium nitrate Substances 0.000 description 1
235000010344 sodium nitrate Nutrition 0.000 description 1
239000002904 solvent Substances 0.000 description 1
238000003756 stirring Methods 0.000 description 1
238000000967 suction filtration Methods 0.000 description 1
239000000725 suspension Substances 0.000 description 1
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

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Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

SU874202677A 1986-06-06 1987-06-05 Способ получени диастереомера N- @ 4-[2-(2-амино-4-гидрокси-5,6,7,8-тетрагидропиридо[2,3- @ ]пиримидин-6-ил)этил]бензоил @ -L-глутаминовой кислоты со значением [ @ ] @ -21,06 @ или диастереомера N- @ 4-[2-(2-амино-4-гидрокси-5,6,7,8-тетрагидропиридо[2,3- @ ]пиримидин-6-ил)этил]бензоил @ -L-глутаминовой кислоты со значением [ @ ] @ +31,09 @ или их фармацевтически приемлемых солей с основанием SU1627087A3 (ru)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US87153986A	1986-06-06	1986-06-06

Publications (1)

Publication Number	Publication Date
SU1627087A3 true SU1627087A3 (ru)	1991-02-07

Family

ID=25357673

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
SU874202677A SU1627087A3 (ru)	1986-06-06	1987-06-05	Способ получени диастереомера N- @ 4-[2-(2-амино-4-гидрокси-5,6,7,8-тетрагидропиридо[2,3- @ ]пиримидин-6-ил)этил]бензоил @ -L-глутаминовой кислоты со значением [ @ ] @ -21,06 @ или диастереомера N- @ 4-[2-(2-амино-4-гидрокси-5,6,7,8-тетрагидропиридо[2,3- @ ]пиримидин-6-ил)этил]бензоил @ -L-глутаминовой кислоты со значением [ @ ] @ +31,09 @ или их фармацевтически приемлемых солей с основанием

Country Status (15)

Country	Link
EP (1)	EP0248573A3 (da)
JP (1)	JPH07116190B2 (da)
KR (1)	KR950004894B1 (da)
CN (1)	CN1019391B (da)
AU (1)	AU592182B2 (da)
CA (1)	CA1301155C (da)
DK (1)	DK170023B1 (da)
EG (1)	EG19551A (da)
ES (1)	ES2003828A6 (da)
GR (1)	GR870783B (da)
NZ (1)	NZ219971A (da)
PH (1)	PH25509A (da)
PT (1)	PT84990B (da)
SU (1)	SU1627087A3 (da)
ZA (1)	ZA873083B (da)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
RU2133748C1 (ru) *	1994-09-06	1999-07-27	Кабусики Кайся Якулт Хонса	Производные камптотецина, способ их получения и противоопухолевая композиция

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IE60038B1 (en) *	1986-06-30	1994-05-18	Univ Princeton	4(3H)-oxo-5, 6, 7, 8-tetrahydropyrido-[2, 3-d]pyrimidine derivatives
GB8625019D0 (en) *	1986-10-18	1986-11-19	Wellcome Found	Compounds
US4895946A (en) *	1987-10-26	1990-01-23	The Trustees Of Princeton University	Process for the preparation of fused pyridine compounds
US4889859A (en) *	1988-02-05	1989-12-26	The Trustees Of Princeton University	Pyrido[2,3-d]pyrimidine derivatives
JP2830008B2 (ja) *	1988-04-01	1998-12-02	武田薬品工業株式会社	縮合ピリミジン誘導体
US5223620A (en) *	1988-04-01	1993-06-29	Takeda Chemical Industries, Ltd.	Pyrido[2,3-d]pyrimidine compounds useful as intermediates
DK172753B1 (da) *	1988-05-25	1999-06-28	Lilly Co Eli	N-(5,6,7,8-tetrahydropyrido[2,3--d]pyrimidin-6-yl-alkanoyl)-glutaminsyrederivater, deres anvendelse, farmaceutiske præparat
US5008391A (en) *	1989-07-07	1991-04-16	Eli Lilly And Company	Enantioselective synthesis of antifolates
US5066828A (en) *	1990-04-12	1991-11-19	Merrell Dow Pharmaceuticals Inc.	Difluoroglutamic acid conjugates with folates and anti-folates for the treatment of neoplastic diseases
EP1054859A4 (en) *	1998-02-11	2003-03-05	Lilly Co Eli	PROCESSES AND INTERMEDIATES USEFUL FOR THE MANUFACTURE OF ANTIFOLICS
CN110749692B (zh) *	2019-10-15	2022-03-18	扬子江药业集团有限公司	L-谷氨酸二乙酯盐酸盐及其光学异构体的分离检测方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ZA861235B (en) *	1985-03-08	1986-10-29	Univ Princeton	Pyrido(2,3-d)pyrimidine derivatives

1987
- 1987-04-14 NZ NZ219971A patent/NZ219971A/xx unknown
- 1987-04-29 ZA ZA873083A patent/ZA873083B/xx unknown
- 1987-05-04 EG EG26087A patent/EG19551A/xx active
- 1987-05-06 DK DK232387A patent/DK170023B1/da not_active IP Right Cessation
- 1987-05-07 JP JP62109938A patent/JPH07116190B2/ja not_active Expired - Fee Related
- 1987-05-12 AU AU72731/87A patent/AU592182B2/en not_active Ceased
- 1987-05-19 GR GR870783A patent/GR870783B/el unknown
- 1987-05-22 EP EP87304580A patent/EP0248573A3/en not_active Withdrawn
- 1987-05-25 CA CA000537814A patent/CA1301155C/en not_active Expired - Lifetime
- 1987-06-02 PT PT84990A patent/PT84990B/pt not_active IP Right Cessation
- 1987-06-04 PH PH35342A patent/PH25509A/en unknown
- 1987-06-05 KR KR1019870005798A patent/KR950004894B1/ko not_active Expired - Fee Related
- 1987-06-05 SU SU874202677A patent/SU1627087A3/ru active
- 1987-06-05 ES ES8701666A patent/ES2003828A6/es not_active Expired
- 1987-06-06 CN CN87104103A patent/CN1019391B/zh not_active Expired

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Грюштейн Дх., Виниц М. Хими аминокислот и пептидов.- М.: Мир, 1965, с.134. *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
RU2133748C1 (ru) *	1994-09-06	1999-07-27	Кабусики Кайся Якулт Хонса	Производные камптотецина, способ их получения и противоопухолевая композиция

Also Published As

Publication number	Publication date
ZA873083B (en)	1987-10-26
NZ219971A (en)	1989-08-29
GR870783B (en)	1987-09-25
PT84990A (en)	1987-07-01
KR950004894B1 (ko)	1995-05-15
CN87104103A (zh)	1987-12-30
AU7273187A (en)	1987-12-10
JPH07116190B2 (ja)	1995-12-13
ES2003828A6 (es)	1988-11-16
KR880000431A (ko)	1988-03-25
PH25509A (en)	1991-07-24
EG19551A (en)	1996-02-29
PT84990B (pt)	1990-03-08
CN1019391B (zh)	1992-12-09
EP0248573A2 (en)	1987-12-09
CA1301155C (en)	1992-05-19
AU592182B2 (en)	1990-01-04
DK170023B1 (da)	1995-05-01
DK232387D0 (da)	1987-05-06
EP0248573A3 (en)	1989-06-14
DK232387A (da)	1987-12-07
JPS6339878A (ja)	1988-02-20

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US2691654A (en)	1954-10-12	Amino heterocycles and method of making
EP0981524B1 (en)	2003-04-23	New intermediates and process for the preparation thereof
EP0553202A1 (en)	1993-08-04	METHOD FOR PRODUCING IMIDAZO [4,5-C] QUINOLIN-4-AMINES.
SU510999A3 (ru)	1976-04-15	Способ получени (метоксиметил-фурилметил)6,7-бензоморфанов илиморфинанов
US4782149A (en)	1988-11-01	Pyridazodiazepine derivatives
ES8404330A1 (es)	1984-05-01	Un metodo para la produccion de derivados de esteres de acidos 1,4-dihidropiridin-3,5-dicarboxilicos.
Regaı̈nia et al.	2000	Synthesis of 1, 2, 5-thiadiazolidines 1, 1-dioxides (cyclosulfamides) starting from amino acids and chlorosulfonyl isocyanate
US6215005B1 (en)	2001-04-10	Intermediates and process for the preparation thereof
DK290779A (da)	1980-01-12	Fremgangsmaade til fremstilling af 1-desoxynojirmycin og n-substituerede derivater deraf
Ueda et al.	1964	Pyrimidines. III. A Novel Rearrangement in the Syntheses of Imidazo-or Pyrimido [1, 2-c] pyrimidines1
NO163770B (no)	1990-04-09	Analogifremgangsmaate ved fremstilling av terapeutisk aktive omega-aminosyreamider.
CN106458880A (zh)	2017-02-22	新型有机硒化合物、其制备方法及其尤其作为抗肿瘤剂的药物用途
SU557758A3 (ru)	1977-05-05	Способ получени 4-азабензимидазолов или их солей
SU453830A3 (ru)	1974-12-15	Способ получения соответственно замещенного фенацетилгуанидина
CA1301155C (en)	1992-05-19	Diastereoisomeric tetrahydropyrido (2,3,-d)pyrimidine derivatives
SU1491332A3 (ru)	1989-06-30	Способ получени оптически-активного карнитиннитрилхлорида
Rao et al.	2007	Enantioselective synthesis and antiviral activity of purine and pyrimidine cyclopentenyl C-nucleosides
US3580923A (en)	1971-05-25	Resolution process
NO764039L (da)	1977-06-06
US3655673A (en)	1972-04-11	Process for the preparation of oxazolidinone derivatives
SU906379A3 (ru)	1982-02-15	Способ получени производных пиридо/1,2-а/пиримидинов или их солей,или их оптически активных изомеров
SU648102A3 (ru)	1979-02-15	Способ получени производных нафтиридинов или их солей
US2749345A (en)	1956-06-05	Pyrimidine compounds
US2592931A (en)	1952-04-15	Thiothiazolone derivatives
DK152501B (da)	1988-03-07	Fremgangsmaade til fremstilling af pyrrolooe1,2-aaapyrimidiner eller salte deraf

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Links

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Landscapes

Applications Claiming Priority (1)

Publications (1)

Family

ID=25357673

Family Applications (1)

Country Status (15)

Cited By (1)

Families Citing this family (11)

Family Cites Families (1)

Non-Patent Citations (1)

Cited By (1)

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