SU604494A3 - Способ получени 2,5-диметилтиено-(3,2- )морфана - Google Patents
Способ получени 2,5-диметилтиено-(3,2- )морфанаInfo
- Publication number
- SU604494A3 SU604494A3 SU762396747A SU2396747A SU604494A3 SU 604494 A3 SU604494 A3 SU 604494A3 SU 762396747 A SU762396747 A SU 762396747A SU 2396747 A SU2396747 A SU 2396747A SU 604494 A3 SU604494 A3 SU 604494A3
- Authority
- SU
- USSR - Soviet Union
- Prior art keywords
- dimethyl
- morphane
- thieno
- preparing
- formula
- Prior art date
Links
- 239000002253 acid Substances 0.000 description 2
- FTAHXMZRJCZXDL-UHFFFAOYSA-N 3-piperideine Chemical compound C1CC=CCN1 FTAHXMZRJCZXDL-UHFFFAOYSA-N 0.000 description 1
- ZBJJDYGJCNTNTH-UHFFFAOYSA-N Betahistine mesilate Chemical group CS(O)(=O)=O.CS(O)(=O)=O.CNCCC1=CC=CC=N1 ZBJJDYGJCNTNTH-UHFFFAOYSA-N 0.000 description 1
- 229910052739 hydrogen Inorganic materials 0.000 description 1
- 239000001257 hydrogen Substances 0.000 description 1
- 125000004435 hydrogen atom Chemical class [H]* 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/08—Bridged systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pain & Pain Management (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
- Saccharide Compounds (AREA)
Description
(54) СПОСОБ ПОЛУЧЕНИЯ 2,5-ДИMETИЛ-TИEHO(3,2-f)MOPФAHA Вычислено. %: с 59,11; Н 7,44; N5.74; а 14,54. Формуле зовр« вии I 1. Сооооб получени 2 димет л- тш о- (3,2-f) морфмш формулы СИз10 . А 27 II / отпи аюшийс тем, что смесь 2-(2 тенил)|, димет л 1,2,3,6тетрагидропнридина формулы ,-20 S . 8 tHg м O-IQ (а) т 2- (2 те|аш)г 1,4-рцтт -1,2, твтрашдроп р й «формулыг . vn« S ««2 И trp СГ W си. агревакпг при темперв у ж 130-135 С в йр сут ств и каслоты. 2. Способ во в., отл чвмщнйс n«i, что в качестве кислоты иаюльзуют (мнсто водородную кислоту.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES441142A ES441142A1 (es) | 1975-09-20 | 1975-09-20 | Un procedimiento para la obtencion de 2, 5-dimetil-tieno (3,2-f) morfano. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SU604494A3 true SU604494A3 (ru) | 1978-04-25 |
Family
ID=8470020
Family Applications (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SU762396747A SU604494A3 (ru) | 1975-09-20 | 1976-09-15 | Способ получени 2,5-диметилтиено-(3,2- )морфана |
| SU772474104A SU633481A3 (ru) | 1975-09-20 | 1977-04-22 | Способ получени 2-тиенил(4-метил-2-пиридил)-кетона |
| SU772472890A SU637084A3 (ru) | 1975-09-20 | 1977-04-22 | Способ получени 2-(2-тенил)1,4-диметил-1,2,5,6-(и1,2,5,6)тетрагидропиридинов |
| SU772472888A SU625611A3 (ru) | 1975-09-20 | 1977-04-22 | Способ получени 2(2-тиенил)4-метилпиридина |
| SU772473620A SU626699A3 (ru) | 1975-09-20 | 1977-04-22 | Способ получени 2/2-тиенил/-1,4-диметилпиридиний бромида |
Family Applications After (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SU772474104A SU633481A3 (ru) | 1975-09-20 | 1977-04-22 | Способ получени 2-тиенил(4-метил-2-пиридил)-кетона |
| SU772472890A SU637084A3 (ru) | 1975-09-20 | 1977-04-22 | Способ получени 2-(2-тенил)1,4-диметил-1,2,5,6-(и1,2,5,6)тетрагидропиридинов |
| SU772472888A SU625611A3 (ru) | 1975-09-20 | 1977-04-22 | Способ получени 2(2-тиенил)4-метилпиридина |
| SU772473620A SU626699A3 (ru) | 1975-09-20 | 1977-04-22 | Способ получени 2/2-тиенил/-1,4-диметилпиридиний бромида |
Country Status (16)
| Country | Link |
|---|---|
| JP (1) | JPS5257193A (ru) |
| AR (1) | AR214297A1 (ru) |
| AT (1) | AT352299B (ru) |
| AU (1) | AU502649B2 (ru) |
| BE (1) | BE845756A (ru) |
| CA (1) | CA1066283A (ru) |
| CH (1) | CH615682A5 (ru) |
| DE (1) | DE2641320C3 (ru) |
| ES (1) | ES441142A1 (ru) |
| FR (5) | FR2324302A1 (ru) |
| GB (1) | GB1553614A (ru) |
| NL (1) | NL7610438A (ru) |
| NZ (1) | NZ181891A (ru) |
| PT (1) | PT65595B (ru) |
| SE (2) | SE7610336L (ru) |
| SU (5) | SU604494A3 (ru) |
-
1975
- 1975-09-20 ES ES441142A patent/ES441142A1/es not_active Expired
-
1976
- 1976-08-30 NZ NZ181891A patent/NZ181891A/xx unknown
- 1976-09-01 BE BE170278A patent/BE845756A/xx unknown
- 1976-09-06 AT AT657776A patent/AT352299B/de not_active IP Right Cessation
- 1976-09-09 GB GB37473/76A patent/GB1553614A/en not_active Expired
- 1976-09-10 AU AU17623/76A patent/AU502649B2/en not_active Expired
- 1976-09-13 CH CH1161476A patent/CH615682A5/fr not_active IP Right Cessation
- 1976-09-14 DE DE2641320A patent/DE2641320C3/de not_active Expired
- 1976-09-15 SU SU762396747A patent/SU604494A3/ru active
- 1976-09-15 PT PT65595A patent/PT65595B/pt unknown
- 1976-09-17 CA CA261,490A patent/CA1066283A/en not_active Expired
- 1976-09-17 JP JP51110937A patent/JPS5257193A/ja active Pending
- 1976-09-17 SE SE7610336A patent/SE7610336L/xx unknown
- 1976-09-20 FR FR7628180A patent/FR2324302A1/fr active Granted
- 1976-09-20 NL NL7610438A patent/NL7610438A/xx not_active Application Discontinuation
- 1976-11-27 AR AR264477A patent/AR214297A1/es active
-
1977
- 1977-04-22 SU SU772474104A patent/SU633481A3/ru active
- 1977-04-22 SU SU772472890A patent/SU637084A3/ru active
- 1977-04-22 SU SU772472888A patent/SU625611A3/ru active
- 1977-04-22 SU SU772473620A patent/SU626699A3/ru active
- 1977-06-03 FR FR7717092A patent/FR2339611A1/fr not_active Withdrawn
- 1977-06-03 FR FR7717089A patent/FR2339608A1/fr not_active Withdrawn
- 1977-06-03 FR FR7717090A patent/FR2339609A1/fr not_active Withdrawn
- 1977-06-03 FR FR7717091A patent/FR2339610A1/fr not_active Withdrawn
-
1980
- 1980-01-10 SE SE8000206A patent/SE8000206L/sv unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE2641320C3 (de) | 1980-04-03 |
| SU625611A3 (ru) | 1978-09-25 |
| FR2339610A1 (fr) | 1977-08-26 |
| NZ181891A (en) | 1979-01-11 |
| PT65595B (fr) | 1978-03-28 |
| FR2324302A1 (fr) | 1977-04-15 |
| FR2339611A1 (fr) | 1977-08-26 |
| BE845756A (fr) | 1977-03-01 |
| AR214297A1 (es) | 1979-05-31 |
| AU1762376A (en) | 1978-03-16 |
| AU502649B2 (en) | 1979-08-02 |
| PT65595A (fr) | 1976-10-01 |
| ATA657776A (de) | 1979-02-15 |
| AT352299B (de) | 1979-09-10 |
| ES441142A1 (es) | 1977-07-01 |
| CA1066283A (en) | 1979-11-13 |
| JPS5257193A (en) | 1977-05-11 |
| SU637084A3 (ru) | 1978-12-05 |
| CH615682A5 (en) | 1980-02-15 |
| SU633481A3 (ru) | 1978-11-15 |
| FR2339608A1 (fr) | 1977-08-26 |
| SE7610336L (sv) | 1977-03-21 |
| DE2641320A1 (de) | 1977-03-24 |
| SU626699A3 (ru) | 1978-09-30 |
| DE2641320B2 (de) | 1979-08-02 |
| NL7610438A (nl) | 1977-03-22 |
| FR2339609A1 (fr) | 1977-08-26 |
| FR2324302B1 (ru) | 1978-12-15 |
| GB1553614A (en) | 1979-09-26 |
| SE8000206L (sv) | 1980-01-10 |
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