SU645577A3 - Способ получени производных тиофена - Google Patents
Способ получени производных тиофенаInfo
- Publication number
- SU645577A3 SU645577A3 SU742057098A SU2057098A SU645577A3 SU 645577 A3 SU645577 A3 SU 645577A3 SU 742057098 A SU742057098 A SU 742057098A SU 2057098 A SU2057098 A SU 2057098A SU 645577 A3 SU645577 A3 SU 645577A3
- Authority
- SU
- USSR - Soviet Union
- Prior art keywords
- thienyl
- mol
- acetonitrile
- mixture
- thiophene derivatives
- Prior art date
Links
- 150000003577 thiophenes Chemical class 0.000 title 1
- UHOVQNZJYSORNB-UHFFFAOYSA-N Benzene Chemical compound C1=CC=CC=C1 UHOVQNZJYSORNB-UHFFFAOYSA-N 0.000 description 27
- WEVYAHXRMPXWCK-UHFFFAOYSA-N Acetonitrile Chemical compound CC#N WEVYAHXRMPXWCK-UHFFFAOYSA-N 0.000 description 23
- 125000001541 3-thienyl group Chemical group S1C([H])=C([*])C([H])=C1[H] 0.000 description 14
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 description 10
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 10
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 10
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 8
- 239000000203 mixture Substances 0.000 description 8
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 6
- ZMXDDKWLCZADIW-UHFFFAOYSA-N N,N-Dimethylformamide Chemical compound CN(C)C=O ZMXDDKWLCZADIW-UHFFFAOYSA-N 0.000 description 6
- 239000000243 solution Substances 0.000 description 6
- AQNQQHJNRPDOQV-UHFFFAOYSA-N bromocyclohexane Chemical compound BrC1CCCCC1 AQNQQHJNRPDOQV-UHFFFAOYSA-N 0.000 description 5
- 239000011541 reaction mixture Substances 0.000 description 5
- 239000000377 silicon dioxide Substances 0.000 description 5
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 5
- XDTMQSROBMDMFD-UHFFFAOYSA-N Cyclohexane Chemical compound C1CCCCC1 XDTMQSROBMDMFD-UHFFFAOYSA-N 0.000 description 4
- 239000003480 eluent Substances 0.000 description 4
- 239000000725 suspension Substances 0.000 description 4
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 3
- KEAYESYHFKHZAL-UHFFFAOYSA-N Sodium Chemical compound [Na] KEAYESYHFKHZAL-UHFFFAOYSA-N 0.000 description 3
- 239000008346 aqueous phase Substances 0.000 description 3
- 238000004587 chromatography analysis Methods 0.000 description 3
- 229910052757 nitrogen Inorganic materials 0.000 description 3
- 239000012299 nitrogen atmosphere Substances 0.000 description 3
- 239000012074 organic phase Substances 0.000 description 3
- 238000002360 preparation method Methods 0.000 description 3
- 229910052708 sodium Inorganic materials 0.000 description 3
- 239000011734 sodium Substances 0.000 description 3
- 229910000104 sodium hydride Inorganic materials 0.000 description 3
- 239000012312 sodium hydride Substances 0.000 description 3
- GWZCLMWEJWPFFA-UHFFFAOYSA-N 2-thiophen-3-ylacetonitrile Chemical compound N#CCC=1C=CSC=1 GWZCLMWEJWPFFA-UHFFFAOYSA-N 0.000 description 2
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 description 2
- IAZDPXIOMUYVGZ-UHFFFAOYSA-N Dimethylsulphoxide Chemical compound CS(C)=O IAZDPXIOMUYVGZ-UHFFFAOYSA-N 0.000 description 2
- GNOIPBMMFNIUFM-UHFFFAOYSA-N hexamethylphosphoric triamide Chemical compound CN(C)P(=O)(N(C)C)N(C)C GNOIPBMMFNIUFM-UHFFFAOYSA-N 0.000 description 2
- 239000012071 phase Substances 0.000 description 2
- 238000010992 reflux Methods 0.000 description 2
- ODZPKZBBUMBTMG-UHFFFAOYSA-N sodium amide Chemical compound [NH2-].[Na+] ODZPKZBBUMBTMG-UHFFFAOYSA-N 0.000 description 2
- CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 description 1
- BVKZGUZCCUSVTD-UHFFFAOYSA-L Carbonate Chemical compound [O-]C([O-])=O BVKZGUZCCUSVTD-UHFFFAOYSA-L 0.000 description 1
- CDBYLPFSWZWCQE-UHFFFAOYSA-L Sodium Carbonate Chemical compound [Na+].[Na+].[O-]C([O-])=O CDBYLPFSWZWCQE-UHFFFAOYSA-L 0.000 description 1
- 239000007864 aqueous solution Substances 0.000 description 1
- 125000003118 aryl group Chemical group 0.000 description 1
- 235000011089 carbon dioxide Nutrition 0.000 description 1
- 239000012259 ether extract Substances 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 238000003756 stirring Methods 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/24—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7331322A FR2242392B1 (da) | 1973-08-30 | 1973-08-30 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SU645577A3 true SU645577A3 (ru) | 1979-01-30 |
Family
ID=9124446
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SU742057098A SU645577A3 (ru) | 1973-08-30 | 1974-08-29 | Способ получени производных тиофена |
Country Status (14)
| Country | Link |
|---|---|
| JP (1) | JPS5050361A (da) |
| BE (1) | BE818306A (da) |
| CA (1) | CA1023368A (da) |
| CH (1) | CH592651A5 (da) |
| DE (1) | DE2441442A1 (da) |
| DK (1) | DK144913C (da) |
| ES (1) | ES429679A1 (da) |
| FR (1) | FR2242392B1 (da) |
| GB (1) | GB1460537A (da) |
| IT (1) | IT1020262B (da) |
| NL (1) | NL7411194A (da) |
| NO (1) | NO142399C (da) |
| SE (1) | SE415258B (da) |
| SU (1) | SU645577A3 (da) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2751652B1 (fr) * | 1996-07-24 | 1998-09-04 | Expansia Sa | Derives du thienylcyclohexane, des procedes pour leur preparation et leur utilisation en tant que produits industriels nouveaux pour la synthese de derives thienylcyclohexyles |
| JP4934412B2 (ja) * | 2006-11-20 | 2012-05-16 | 株式会社グラウンドデザイン研究所 | 手持ち用の簡易計量容器 |
-
1973
- 1973-08-30 FR FR7331322A patent/FR2242392B1/fr not_active Expired
-
1974
- 1974-07-31 BE BE147126A patent/BE818306A/xx unknown
- 1974-08-14 GB GB3587874A patent/GB1460537A/en not_active Expired
- 1974-08-22 NL NL7411194A patent/NL7411194A/xx not_active Application Discontinuation
- 1974-08-27 CH CH1167074A patent/CH592651A5/xx not_active IP Right Cessation
- 1974-08-28 JP JP49099448A patent/JPS5050361A/ja active Pending
- 1974-08-29 IT IT26698/74A patent/IT1020262B/it active
- 1974-08-29 DE DE2441442A patent/DE2441442A1/de not_active Withdrawn
- 1974-08-29 SE SE7410953A patent/SE415258B/xx unknown
- 1974-08-29 SU SU742057098A patent/SU645577A3/ru active
- 1974-08-29 DK DK459774A patent/DK144913C/da active
- 1974-08-29 CA CA208,277A patent/CA1023368A/en not_active Expired
- 1974-08-29 NO NO743097A patent/NO142399C/no unknown
- 1974-08-30 ES ES429679A patent/ES429679A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| SE7410953L (da) | 1975-03-03 |
| DE2441442A1 (de) | 1975-03-06 |
| NO142399C (no) | 1980-08-13 |
| FR2242392A1 (da) | 1975-03-28 |
| BE818306A (fr) | 1975-01-31 |
| IT1020262B (it) | 1977-12-20 |
| CA1023368A (en) | 1977-12-27 |
| DK144913B (da) | 1982-07-05 |
| GB1460537A (en) | 1977-01-06 |
| CH592651A5 (da) | 1977-10-31 |
| NO142399B (no) | 1980-05-05 |
| DK144913C (da) | 1982-11-22 |
| NL7411194A (nl) | 1975-03-04 |
| SE415258B (sv) | 1980-09-22 |
| DK459774A (da) | 1975-04-28 |
| NO743097L (da) | 1975-03-24 |
| FR2242392B1 (da) | 1979-10-19 |
| ES429679A1 (es) | 1976-10-01 |
| JPS5050361A (da) | 1975-05-06 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| USRE29650E (en) | Phthalide penicillin ester intermediates | |
| Martin et al. | Synthesis of 1, 4-substituted imidazoles | |
| US4966973A (en) | 2-substituted coumaran derivatives | |
| SU645577A3 (ru) | Способ получени производных тиофена | |
| US5329049A (en) | Process for the preparation of substituted indanones | |
| US6515147B2 (en) | 3-(1-hydroxy-pentylidene)-5-nitro-3H-benzofuran-2-one a process for the preparation thereof and the use thereof | |
| SU1375142A3 (ru) | Способ получени сахарных кеталей | |
| JPH06192163A (ja) | 置換インダノンの製造方法 | |
| CA1135705A (en) | N-arylsulfonylpyrroles, their preparation, and therapeutic agents containing these compounds | |
| KR920003101B1 (ko) | 디아릴인단-1,3-디온의 제조방법 | |
| Ford et al. | 5-Substituted 2-Thiopheneacetic Acids and Amides as Penicillin Precursors | |
| SU843732A3 (ru) | Способ получени замещенной инданилуксусной кислоты | |
| US5107004A (en) | 2-neopentylanthraquinone, processes for its preparation and methods for its use | |
| CN114516800A (zh) | 一种2-(4-硝基苯基)丁酸的合成方法 | |
| US4228105A (en) | 4-Biphenylyl-4-hydroxyalkan-2-ones | |
| US4031136A (en) | Process for the preparation of trans, trans-muconic acid | |
| US4196299A (en) | Process for manufacturing thienyl-2 acetic acid | |
| US4213905A (en) | Preparation of 5-aroyl-1-loweralkylpyrrole-2-acetic acid salts | |
| CN118324740B (zh) | 一种合成9,10-二氢-4h-苯并[4,5]环庚三烯[1,2-b]噻吩-4-酮的方法及其应用 | |
| JP3047582B2 (ja) | トレオ−４−アルコキシ−５−（アリールヒドロキシメチル）−２（５ｈ）−フラノンの製造方法 | |
| EP0101004A1 (en) | Process for preparing 4-oxo-4, 5, 6, 7-tetrahydroindole derivative | |
| EP0101003B1 (en) | Process for preparing 4-oxo-4,5,6,7-tetrahydrobenzofuran derivative | |
| FR2600333A1 (fr) | Procede pour la preparation de 4-alcoxy-3-pyrroline-2-ones | |
| BE858864A (fr) | Nouveaux esters d'acides phenyl- et pyridine-3-carboxylique et procede permettant leur preparation | |
| SU1684278A1 (ru) | Способ получени хлорангидрида N-карбометоксисульфаниловой кислоты |