SV2002000204A - Metodos para usar 22045, una fosfodiesterasa humana de nucleotidos ciclicos - Google Patents

Metodos para usar 22045, una fosfodiesterasa humana de nucleotidos ciclicos

Info

Publication number
SV2002000204A
SV2002000204A SV2000000204A SV2000000204A SV2002000204A SV 2002000204 A SV2002000204 A SV 2002000204A SV 2000000204 A SV2000000204 A SV 2000000204A SV 2000000204 A SV2000000204 A SV 2000000204A SV 2002000204 A SV2002000204 A SV 2002000204A
Authority
SV
El Salvador
Prior art keywords
methods
phosphodesterase
phosphodiesterase
polynucleotides
human
Prior art date
Application number
SV2000000204A
Other languages
English (en)
Inventor
Rosana Kapeller-Libermann
John Joseph Hunter
Mark Williamson
Original Assignee
Millennium Pharm Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Millennium Pharm Inc filed Critical Millennium Pharm Inc
Publication of SV2002000204A publication Critical patent/SV2002000204A/es

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/16Hydrolases (3) acting on ester bonds (3.1)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00Drugs for disorders of the endocrine system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Genetics & Genomics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Zoology (AREA)
  • Public Health (AREA)
  • Wood Science & Technology (AREA)
  • Cardiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Diabetes (AREA)
  • Hospice & Palliative Care (AREA)
  • Endocrinology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)

Abstract

METODOS PARA USAR UNA FOSFODIESTERASA HUMANA DE NUCLEOTIDOS CICLICOS QUE PERTENECEN A LA SUPERFAMILIA DE LAS FOSFODIESTERASA DE MAMIFEROS.LA INVENCION SE RELACIONA TAMBIEN CON METODOS PARA USAR LOS POLINUCLEICOS QUE CODIFICAN LA FOSFODIESTERASA. LA INVENCION SE RELACIONA CON METODOS PARA USAR LOS POLIPEPTIDOS Y LOS POLINUCLEOTIDOS DE LA FOSFODIESTERASA COMO UN BLANCO PARA LA DIAGNOSIS Y EL TRATAMIENTO DE AFECCIONES MEDIADAS O RELACIONADAS CON LA FOSFODIESTERASA. LA INVENCION SE RELACIONA ADEMAS CON METODOS PARA EL ANALISIS DE DROGAS QUE USAN LOS POLIPEPTIDOS Y LOS POLINUCLEOTIDOS DE LA FOSFODIESTERASA PARA INDENTIFICAR AGONISTAS Y ANTAGONISTAS PARA DIAGNOSIS Y TRATAMIENTOS. LA INVENCION SE ABARCA ADEMAS AGONISTAS Y ANTAGONISTAS BASADOS EN LOS POLIPEPTIDOS Y EN LO POLINUCLEOTIDOS DE LA FOSFODIESTERASA. LA INVENCION SE RELACIONA ADEMAS CON AGONISTAS Y ANTAGONISTAS IDENTIFICADOS POR MEDIO DE LOS METODOS DE ANALISIS DE DROGAS CON LOS POLIPEPTIDOS Y LOS POLINUCLEOTIDOS DE LA FOSFODIESTERASA COMO BLANCO.
SV2000000204A 1999-10-18 2000-10-18 Metodos para usar 22045, una fosfodiesterasa humana de nucleotidos ciclicos SV2002000204A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US09/420,190 US6673564B2 (en) 1999-10-18 1999-10-18 Methods for using 22045, a human cyclic nucleotide phosphodiesterase

Publications (1)

Publication Number Publication Date
SV2002000204A true SV2002000204A (es) 2002-09-12

Family

ID=23665445

Family Applications (1)

Application Number Title Priority Date Filing Date
SV2000000204A SV2002000204A (es) 1999-10-18 2000-10-18 Metodos para usar 22045, una fosfodiesterasa humana de nucleotidos ciclicos

Country Status (10)

Country Link
US (2) US6673564B2 (es)
EP (1) EP1224268A1 (es)
JP (1) JP2003512049A (es)
AU (1) AU8028900A (es)
CO (1) CO5280155A1 (es)
DO (1) DOP2000000081A (es)
GT (1) GT200000181A (es)
PE (1) PE20010808A1 (es)
SV (1) SV2002000204A (es)
WO (1) WO2001029199A1 (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7745142B2 (en) * 1997-09-15 2010-06-29 Molecular Devices Corporation Molecular modification assays
US7632651B2 (en) 1997-09-15 2009-12-15 Mds Analytical Technologies (Us) Inc. Molecular modification assays
JP2001302667A (ja) * 2000-04-28 2001-10-31 Bayer Ag イミダゾピリミジン誘導体およびトリアゾロピリミジン誘導体
US6930114B2 (en) 2000-12-13 2005-08-16 Bayer Pharmaceuticals Corporation Pyrrolo (2.1a)dihydroisoquinolines and their use as phosphodiesterase 10a inhibitors
CN101259120B (zh) 2002-03-04 2012-07-04 Hdac默克研究有限责任公司 辛二酰苯胺异羟肟酸或其可药用盐在制备诱导末期分化的药物的用途
US7456219B2 (en) 2002-03-04 2008-11-25 Merck Hdac Research, Llc Polymorphs of suberoylanilide hydroxamic acid
AU2002953285A0 (en) * 2002-12-12 2003-01-02 Protech Research Pty Ltd Yeast treatment

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5798246A (en) * 1996-03-25 1998-08-25 Incyte Pharmaceuticals, Inc. Cyclic nucleotide phosphodiesterase
US5858694A (en) * 1997-05-30 1999-01-12 Cell Pathways, Inc. Method for identifying compounds for inhibition of cancerous lesions
US5932465A (en) * 1997-10-16 1999-08-03 Icos Corporation Phosphodiesterase 8A
IL137164A0 (en) * 1998-01-23 2001-07-24 Newbiotics Inc Enzyme catalyzed therapeutic agents
US6114111A (en) * 1998-03-30 2000-09-05 Rigel Pharmaceuticals, Inc. Mammalian protein interaction cloning system
EP0967284A1 (en) 1998-05-28 1999-12-29 Pfizer Limited Phosphodiesterases
US6100037A (en) * 1999-01-07 2000-08-08 Incyte Pharmaceuticals, Inc. Human cyclic nucleotide PDEs

Also Published As

Publication number Publication date
AU8028900A (en) 2001-04-30
PE20010808A1 (es) 2001-08-22
CO5280155A1 (es) 2003-05-30
JP2003512049A (ja) 2003-04-02
US20020081633A1 (en) 2002-06-27
DOP2000000081A (es) 2002-09-16
EP1224268A1 (en) 2002-07-24
GT200000181A (es) 2002-04-11
US20030215898A1 (en) 2003-11-20
US6673564B2 (en) 2004-01-06
WO2001029199A1 (en) 2001-04-26

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