TH143368A - Methods for the production of target substances by fermentation. - Google Patents

Abstract

DC60 (08/05/57) By cultivating bacteria capable of producing 2-ketoglutaric acid or its derivatives as target compounds and the ability to produce xylonic acid from xylose, which was enhanced by xylonate dehydratase activity, 2-keto-3-deoxyxylonate dehydratase activity and 2-ketoglutaric semialdehyde dehydrogenase activity, or these activities were enhanced in a medium containing xylose as a carbon source, to produce and accumulate the target compounds in the medium and to collect the target compounds from the medium. The target compounds were produced by cultivating bacteria capable of producing 2-ketoglutaric acid or its derivatives as target compounds and the ability to produce xylonic acid from xylose. which is produced by xylonate dehydratase activity, 2-keto-3-deoxyxylonate dehydratase activity and 2-ketoglutaric semialdehyde dehydrogenase activity, or these activities are increased in a medium containing xylose as a carbon source, to produce and accumulate target compounds in the medium and to collect target compounds from the medium. Target compounds are produced.

Claims (1)

: DC60 (08/05/57) By cultivating bacteria capable of producing 2-ketoglutaric acid or its derivatives as target compounds and the ability to produce xylonic acid from xylose, which was enhanced by xylonate dehydratase activity, 2-keto-3-deoxyxylonate dehydratase activity and 2-ketoglutaric semialdehyde dehydrogenase activity, or in which these activities were enhanced in a medium containing xylose as a carbon source, to produce and accumulate the target compounds in the medium and to collect the target compounds from the medium. The target compounds were produced by cultivating bacteria capable of producing 2-ketoglutaric acid or its derivatives as target compounds and the ability to produce xylonic acid from xylose. which is made up of xylonate dehydratase activity, 2-keto-3-deoxyxylonate dehydratase activity and 2-ketoglutaric semialdehyde dehydrogenase activity, or wherein these activities are increased in a medium containing xylose as a carbon source, to produce and accumulate the target substance in the medium and to collect the target substance from the medium, the target substance being produced according to claim (1) which appears on the advertising page: 1. A method for producing a target substance comprising cultivating bacteria capable of producing the target substance in a medium containing xylose as a carbon source to produce and accumulate the target substance in the medium, and collecting the target substance from the medium, where: the target substance is 2-ketoglutaric acid or a derivative thereof; the bacteria capable of producing xylonic acid from xylose, and xylonate dehydrogenase: