TH168085A - Preparations of a pharmaceutical combination containing HMG-coeridectase inhibitors and cholesterol absorption inhibitors. - Google Patents
Preparations of a pharmaceutical combination containing HMG-coeridectase inhibitors and cholesterol absorption inhibitors.Info
- Publication number
- TH168085A TH168085A TH1601003448A TH1601003448A TH168085A TH 168085 A TH168085 A TH 168085A TH 1601003448 A TH1601003448 A TH 1601003448A TH 1601003448 A TH1601003448 A TH 1601003448A TH 168085 A TH168085 A TH 168085A
- Authority
- TH
- Thailand
- Prior art keywords
- inhibitors
- coeridectase
- pharmaceutical combination
- cholesterol absorption
- preparations
- Prior art date
Links
- 239000003112 inhibitor Substances 0.000 title claims abstract 5
- 238000002360 preparation method Methods 0.000 title claims abstract 5
- 230000001906 cholesterol absorption Effects 0.000 title 1
- 229940079593 drug Drugs 0.000 claims abstract 5
- 239000003814 drug Substances 0.000 claims abstract 5
- 229940122502 Cholesterol absorption inhibitor Drugs 0.000 claims abstract 2
- 102000004190 Enzymes Human genes 0.000 claims 1
- 108090000790 Enzymes Proteins 0.000 claims 1
- AEMRFAOFKBGASW-UHFFFAOYSA-M Glycolate Chemical compound OCC([O-])=O AEMRFAOFKBGASW-UHFFFAOYSA-M 0.000 claims 1
- 229920002153 Hydroxypropyl cellulose Polymers 0.000 claims 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 claims 1
- 239000001863 hydroxypropyl cellulose Substances 0.000 claims 1
- 235000010977 hydroxypropyl cellulose Nutrition 0.000 claims 1
- BPRHUIZQVSMCRT-VEUZHWNKSA-N rosuvastatin Chemical compound CC(C)C1=NC(N(C)S(C)(=O)=O)=NC(C=2C=CC(F)=CC=2)=C1\C=C\[C@@H](O)C[C@@H](O)CC(O)=O BPRHUIZQVSMCRT-VEUZHWNKSA-N 0.000 claims 1
- 229960000672 rosuvastatin Drugs 0.000 claims 1
- 229910052708 sodium Inorganic materials 0.000 claims 1
- 239000011734 sodium Substances 0.000 claims 1
- 238000006467 substitution reaction Methods 0.000 claims 1
- 239000004480 active ingredient Substances 0.000 abstract 3
- 239000013543 active substance Substances 0.000 abstract 1
- 238000004090 dissolution Methods 0.000 abstract 1
Abstract
การประดิษฐ์นี้ได้ให้ยาเตรียมของการรวมกันทางเภสัชกรรมซึ่งประกอบด้วย สารออกฤทธิ์ทั้งสอง (ตัว ยับยั้งเอนไซม์เอชเอ็มจี-โคเอ รีดัคเตส และ ตัวยับยั้งการดูดซึมคลอเลสเตอรอล) ในขณะเดียวกัน และมีลักษณะ เฉพาะที่รูปแบบการละลายของแต่ละสารออกฤทธิ์ในยาเตรียมของการรวมกันเป็นเช่นเดียวกับที่เป็นของแต่ละ สารออกฤทธิ์ในยาเตรียมที่เป็นสารออกฤทธิ์เดี่ยว จึงปรับปรุงความสะดวกสบายและความร่วมมือในการใช้ยา ของผู้ป่วยได้อย่างน่าประหลาดใจ สิทธิบัตรยา This invention provided a drug preparation of a pharmaceutical combination consisting of The two active substances (HMG-coeridectase inhibitor and cholesterol absorption inhibitor) are at the same time and are characterized by the dissolution pattern of each. The active ingredients in combination preparations are the same as that of the individual. The active ingredient in the drug is a single active ingredient. Thus improving the comfort and cooperation in the use of drugs. The patient's patents were astonishing.
Claims (2)
Publications (2)
| Publication Number | Publication Date |
|---|---|
| TH1601003448A TH1601003448A (en) | 2017-09-21 |
| TH168085A true TH168085A (en) | 2017-09-21 |
Family
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