TH64685A - 1- methyl-2- (4-amidinophenilaminomethyl) -benzimidazol-5-il-carboxylic acid - (N-2-fir Dill-N-2-hydroxycarbonyl ethyl) - ame New prototype drug type Preparation of the substance and its use as a pharmaceutical mixture - Google Patents
1- methyl-2- (4-amidinophenilaminomethyl) -benzimidazol-5-il-carboxylic acid - (N-2-fir Dill-N-2-hydroxycarbonyl ethyl) - ame New prototype drug type Preparation of the substance and its use as a pharmaceutical mixtureInfo
- Publication number
- TH64685A TH64685A TH301002868A TH0301002868A TH64685A TH 64685 A TH64685 A TH 64685A TH 301002868 A TH301002868 A TH 301002868A TH 0301002868 A TH0301002868 A TH 0301002868A TH 64685 A TH64685 A TH 64685A
- Authority
- TH
- Thailand
- Prior art keywords
- substance
- amidinophenilaminomethyl
- dill
- ame
- benzimidazol
- Prior art date
Links
- 239000000126 substance Substances 0.000 title claims abstract 6
- 229940079593 drug Drugs 0.000 title claims abstract 3
- 239000003814 drug Substances 0.000 title claims abstract 3
- 239000000203 mixture Substances 0.000 title 1
- 150000003839 salts Chemical class 0.000 claims abstract 5
- 150000001875 compounds Chemical class 0.000 claims abstract 3
- 125000004435 hydrogen atom Chemical group [H]* 0.000 claims 2
- 125000004169 (C1-C6) alkyl group Chemical group 0.000 claims 1
- 125000000217 alkyl group Chemical group 0.000 claims 1
- 125000004432 carbon atom Chemical group C* 0.000 claims 1
- -1 carbonyl methoxy group Chemical group 0.000 claims 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims 1
- 125000001449 isopropyl group Chemical group [H]C([H])([H])C([H])(*)C([H])([H])[H] 0.000 claims 1
- 125000000999 tert-butyl group Chemical group [H]C([H])([H])C(*)(C([H])([H])[H])C([H])([H])[H] 0.000 claims 1
- 239000002253 acid Substances 0.000 abstract 2
- 150000007513 acids Chemical class 0.000 abstract 2
- 230000000694 effects Effects 0.000 abstract 2
- 230000002401 inhibitory effect Effects 0.000 abstract 2
- 150000007529 inorganic bases Chemical class 0.000 abstract 2
- SQUHHTBVTRBESD-UHFFFAOYSA-N Hexa-Ac-myo-Inositol Natural products CC(=O)OC1C(OC(C)=O)C(OC(C)=O)C(OC(C)=O)C(OC(C)=O)C1OC(C)=O SQUHHTBVTRBESD-UHFFFAOYSA-N 0.000 abstract 1
- CDAISMWEOUEBRE-GPIVLXJGSA-N inositol Chemical compound O[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@H](O)[C@@H]1O CDAISMWEOUEBRE-GPIVLXJGSA-N 0.000 abstract 1
- 229960000367 inositol Drugs 0.000 abstract 1
- CDAISMWEOUEBRE-UHFFFAOYSA-N scyllo-inosotol Natural products OC1C(O)C(O)C(O)C(O)C1O CDAISMWEOUEBRE-UHFFFAOYSA-N 0.000 abstract 1
Abstract
DC60 (27/10/46) การประดิษฐ์นี้เกี่ยวข้องกับสารประกอบใหม่ที่มีสูตรทั่วไป (สูตรเคมี) (I), ซึ่ง R' และ R ได้ถูกนิยามตามในข้อถือสิทธิข้อ 1 ทอโทเมอร์ และเกลือของสารนั้น โดย เฉพาะเกลือของสารนั้นที่ยอมรับได้ทางสรีรวิทยากับกรด หรือเบสอนินทรีย์ ซึ่งมีสมบัติที่มีค่าโดย เฉพาะการออกฤทธิ์ยับยั้งทรอมบิน การประดิษฐ์นี้เกี่ยวข้องกับสารประกอบใหม่ที่มีสูตรทั่วไป (สูตรทางเคมี) (I), ซึ่ง R' และ R ได้ถูกนิยามตามในข้อถือสิทธิข้อ 1 ทอโทเมอร์ และเกลือของสารนั้น โดย เฉพาะเกลือของสารนั้นที่ยอมรับได้ทางสรีรวิทยากับกรด หรือเบสอนินทรีย์ ซึ่งมีสมบัติที่มีค่าโดย เฉพาะการออกฤทธิ์ยับยั้งทรอมบิน สิทธิบัตรยา DC60 (27/10/46) This invention involves a new compound with the general formula (chemical formula) (I), where R 'and R are defined in the Clause 1, the invention of the thermomer and its salts. That especially the salts of that substance are physiologically acceptable to acids Or inorganic base Which has properties that are valuable by Only the effect of inhibiting Trombin. The invention involved a new compound with a general formula. (Chemical formula) (I), where R 'and R are defined in Clause 1, the inositol and its salts, especially those salts that are physiologically acceptable to acids. Or inorganic base Which has properties that are valuable by Only the effect of inhibiting Trombin, drug patents.
Claims (2)
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TH64685A true TH64685A (en) | 2004-10-14 |
Family
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| TH64685A (en) | 1- methyl-2- (4-amidinophenilaminomethyl) -benzimidazol-5-il-carboxylic acid - (N-2-fir Dill-N-2-hydroxycarbonyl ethyl) - ame New prototype drug type Preparation of the substance and its use as a pharmaceutical mixture |