TH68407A - 3-pyridyl-4-aeril peril, replaced. And methods of treatment and prevention of related diseases - Google Patents
3-pyridyl-4-aeril peril, replaced. And methods of treatment and prevention of related diseasesInfo
- Publication number
- TH68407A TH68407A TH1001684A TH0001001684A TH68407A TH 68407 A TH68407 A TH 68407A TH 1001684 A TH1001684 A TH 1001684A TH 0001001684 A TH0001001684 A TH 0001001684A TH 68407 A TH68407 A TH 68407A
- Authority
- TH
- Thailand
- Prior art keywords
- pyridyl
- replaced
- prevention
- aeril
- peril
- Prior art date
Links
- 201000010099 disease Diseases 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title 1
- 230000002265 prevention Effects 0.000 title 1
- 239000000126 substance Substances 0.000 claims abstract 4
- 150000001875 compounds Chemical class 0.000 claims abstract 2
- 239000003814 drug Substances 0.000 claims abstract 2
- 229940079593 drug Drugs 0.000 claims abstract 2
- RAXXELZNTBOGNW-UHFFFAOYSA-N imidazole Natural products C1=CNC=N1 RAXXELZNTBOGNW-UHFFFAOYSA-N 0.000 claims 4
- NQRYJNQNLNOLGT-UHFFFAOYSA-N Piperidine Chemical compound C1CCNCC1 NQRYJNQNLNOLGT-UHFFFAOYSA-N 0.000 claims 2
- 125000000217 alkyl group Chemical group 0.000 claims 2
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 claims 2
- OGYGFUAIIOPWQD-UHFFFAOYSA-N 1,3-thiazolidine Chemical compound C1CSCN1 OGYGFUAIIOPWQD-UHFFFAOYSA-N 0.000 claims 1
- AGIJRRREJXSQJR-UHFFFAOYSA-N 2h-thiazine Chemical compound N1SC=CC=C1 AGIJRRREJXSQJR-UHFFFAOYSA-N 0.000 claims 1
- 125000003282 alkyl amino group Chemical group 0.000 claims 1
- 229910052739 hydrogen Inorganic materials 0.000 claims 1
- 239000001257 hydrogen Substances 0.000 claims 1
- 125000004435 hydrogen atom Chemical class [H]* 0.000 claims 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims 1
- 150000003839 salts Chemical class 0.000 claims 1
- 239000000203 mixture Substances 0.000 abstract 3
- MZOFCQQQCNRIBI-VMXHOPILSA-N (3s)-4-[[(2s)-1-[[(2s)-1-[[(1s)-1-carboxy-2-hydroxyethyl]amino]-4-methyl-1-oxopentan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-3-[[2-[[(2s)-2,6-diaminohexanoyl]amino]acetyl]amino]-4-oxobutanoic acid Chemical compound OC[C@@H](C(O)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](CC(O)=O)NC(=O)CNC(=O)[C@@H](N)CCCCN MZOFCQQQCNRIBI-VMXHOPILSA-N 0.000 abstract 2
- 108060008682 Tumor Necrosis Factor Proteins 0.000 abstract 2
- 102000000852 Tumor Necrosis Factor-alpha Human genes 0.000 abstract 2
- 230000006806 disease prevention Effects 0.000 abstract 2
Abstract
DC60 (10/08/43) การประดิษฐ์นี้จัดหา 3-ไพริดิล-4-แอริลพิร์โรลที่ถูกแทนที่ชนิดใหม่และสารผสมเชิงเภสัช กรรมซึ่งประกอบรวมด้วยสารนี้ ซึ่งมีประโยชน์สำหรับรักษาการเสียระเบียบ ซึ่งเยียวยาโดย การลด การผลิต TNF - แอลฟา และ/หรือฤทธิ์ p38 ในเซลล์ที่เหมาะ สม การประดิษฐ์นี้จัดหาวิธีการรักษาโรคและ การป้องกันโรค ด้วยโดยการใช้สารผสมเชิงเภสัชกรรมนี้ การประดิษฐ์นี้จัดหา 3-ไพริดิล-4-แอริลพิร์โรลที่ถูกแทนที่ชนิดใหม่และสารผสมเชิงเภสัช กรรมซึ่งประกอบรวมด้วยสารนี้ ซึ่งมีประโยชน์สำหรับรักษาการเสียระเบียบ ซึ่งเยียวยาโดย การลด การผลิต TNF - อัลฟา และ/หรือฤทธิ์ p38 ในเซลล์ที่เหมาะ สม การประดิษฐ์นี้จัดหาวิธีการรักษาโรคและ การป้องกันโรค ด้วยโดยการใช้สารผสมเชิงเภสัชกรรมนี้ สิทธิบัตรยา DC60 (10/08/43) this invention supply New-substituted 3-pyridyl-4-aryl pirroll and pharmaceutical mixtures Karma which consists of this substance Which is useful for keeping the mess. This was modified by reducing the production of TNF-alpha and / or p38 in ideal cells. Disease prevention Also by using this pharmaceutical mixture This invention provides New-substituted 3-pyridyl-4-aryl pirroll and pharmaceutical mixtures Karma which consists of this substance Which is useful for keeping the mess. This remedies by reducing TNF-alpha and / or p38 production in the cells that are optimized. Disease prevention Also, by using this pharmaceutical compound, the drug patent
Claims (1)
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TH68407A true TH68407A (en) | 2005-04-29 |
Family
ID=
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| NO20055092L (en) | Substituted pyrimid ions | |
| UY25679A1 (en) | QUINOLIN-2-ONA DERIVATIVES FARNESIL PROTEIN TRANSFER INHIBITORS USEFUL AS AGENTS AGAINST CANCER | |
| MY144655A (en) | Pyrimidine urea derivatives as kinase inhibitors | |
| EP1489077A4 (en) | 2-FURANCARBOXYLIC ACID HYDRAZIDES AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAME | |
| NO20052493L (en) | Selected CGRP antagonists, processes for their preparation and their use as pharmaceutical compositions. | |
| PE20070218A1 (en) | AMINO-HYDANTOIN CYCLOALKYL COMPOUNDS AND USE OF THESE FOR THE MODULATION OF ß-SECRETASE | |
| NO20056007L (en) | Double NK1 / NK3 antagonists for the treatment of schizophrenia | |
| NO20052496L (en) | Selected CGRP antagonists, methods for their preparation and use thereof as drugs. | |
| WO2005056524A3 (en) | Therapeutic agents useful for treating pain | |
| DE68915225D1 (en) | Benzazole derivatives, processes for their preparation and pharmaceutical compositions containing them. | |
| GEP20094605B (en) | Pyrazole derivatives, compositions containing such compounds and methods of use thereof | |
| EP1396493A4 (en) | Heterocyclic compounds | |
| NO324219B1 (en) | Phenylpyridazine compounds, drugs and pharmaceutical compositions containing them and their use in the manufacture of medicaments for the treatment of disease | |
| DK1463487T3 (en) | Liposomal delivery of vitamin-E based compounds | |
| NO20052683L (en) | New pyridopyrimidinone compounds, processes for their preparation and pharmaceutical compositions containing them | |
| AP9901578A0 (en) | Sulfonylbenzene compounds as anti-inflammatory/analgesic agents. | |
| SE0201194D0 (en) | New compounds | |
| WO2007125398A3 (en) | : sulfonamide compounds as antagonists of the n-type calcium channel | |
| NO20023001L (en) | Substituted piperazine derivatives as MTP inhibitors | |
| ATE444961T1 (en) | HYDRAZIDE TYPE COMPOUNDS AND THEIR USE IN PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF CARDIOVASCULAR DISEASES | |
| NO20060383L (en) | Substituted diketopiperazines and their use as oxytocin antagonists | |
| TH68407A (en) | 3-pyridyl-4-aeril peril, replaced. And methods of treatment and prevention of related diseases | |
| HUT45840A (en) | Fungicides containing as active substance mixtures of derivatives of n-alpha-/2-cyan-2-alkoximino-acetyl/-amin acid and peptide e/z izomers and their clean z-izomers and process for production of the active substances | |
| NO933558L (en) | Benzimidazoles, drugs containing these compounds, and process for their preparation | |
| ATE440835T1 (en) | HETEROCYCLIC UREA DERIVATIVES FOR THE TREATMENT OF PAIN. |