TH69980A - Benzodiazepines and benzocyoxol derivatives replaced with (dihelopropyl) phenyl alkyl that kill pests. - Google Patents

Abstract

DC60 (08/07/47), benzodiazepines and benzodiazole derivatives replaced. (Dihelopropenil) A new definite phenyl alkyl has been released. Unexpected insecticidal activity These compounds are represented by the general formula I (chemical formula) I where R to R10, including x, A, B, y, D, E, G and M are all described here. Popular compound Of invention This is guys, where the benzo-fused loop is attached to the rest of the molecule at a given position of 1 or 2. In addition, a mixture containing an insecticidal content of at least one of the compounds of Formula I and may choose the quantity available The result of at least one Second compound With at least one The insecticide compatible vectors were disclosed, followed by a method of insect control, which consisted of giving the mixture to the flaws. Where the insect is, or Expected to exist Benzodiazepines and benzodiazole derivatives are replaced with (Dihelopropenil) A new definite phenyl alkyl has been released. Unexpected insecticidal activity These compounds are represented by the general formula I (chemical formula) I where R to R10, including x, A, B, y, D, E, G and M are all described here. Popular compound Of invention This is guys, where the benzo-fused loop is attached to the rest of the molecule at a given position of 1 or 2. In addition, the mixtures containing insecticidal quantities of at least one of the compounds of Formula I and may choose the quantity available The result of at least one Second compound With at least one The insecticide compatible vectors were disclosed, followed by a method of insect control, which consisted of giving the mixture to the flaws. Where the insect is, or Expected to exist

Claims (17)

1. Compounds of formula I (chemical formula) I at -R and R3 are freely selected from hydrogen, halogen, hydroxyl, (C1-C3) alkyl, (C3-C6) cycloalkyl, (C2-C5)alkinyl, (C2-C5)alkinyl, halo(C1-C3)alkyl, (C1-C3)alkoxy, halo(C1-C3)alkoxy, (C1-C3)alkylthio, halo(C1-C3)alkylthio, (C1-C3)alkylsulfonyl, halo(C1-C3)alkylsulfonyl, cyano, nitro, amino, which may be selected as substitutes at the potential substitutes. Selective substitution options are available from (C1-C4) alkyl, (C1-C3) alkylcarbonyl, and (C1-C3) alkoxycarbonyl, selectable imidazolyl, selectable imidazolinyl, selectable oxazolinnyl, selectable oxazolil, and selectable oxadiazolyl. The potential substitutes are: thiazolyl, pyrazolyl, triazolyl, furanyl, tetrahydrofuranyl, dioxolanyl, dioxanyl, -C(=J)-K, and -C(R12)-Q-R13, where the potential substitute is chosen from (C1-C4) alkyls, halo(C1-C4)alkyls, (C1-C4)alkoxy, (C1-C4)alkoxy(C1-C4)alkyls, (C3-C6)cycloalkyls, (C2-C5)alkinyls, (C2-C5)alkinyls, cyano, nitro, and aryl, where J is chosen from O, S, NR14, and NOR14, where R14 is hydrogen, (C1-C4) alkyl, halo(C1-C4) alkyl, aryl, and aryl(C1-C4) alkyl, K is chosen from hydrogen, (C1-C3) alkyl, halo(C1-C3) alkyl, (C1-C3) alkoxy, (C1-C3) alkyl amino, and di(C1-C3) alkylamino, Q is chosen from O, S, and NR14 where R14 is as described above. R12 and R13 are chosen independently from hydrogen, (C1-C4) alkyl, and halo(C1-C4) alkyl, and R12 and R13 may be combined with -T(CHR14)m-, where m is an integer 2 to 4, T is chosen from O, S, and NR14 where R14 is as described above. -R1 and R2 -R4 is selected independently from hydrogen, halogen, and (C1-C3)alkyl, -R4 is hydrogen, -R5 and R6 are selected independently from hydrogen, -E is selected from CH2, O, S, and NR15, where R15 is selected from hydrogen, (C1-C3)alkyl, (C1-C3)alkoxy(C1-C3)alkyl, aryl(C1-C3)alkyl, (C2-C4)alkenyl(C1-C3)alkyl, halo(C2-C4)alkenyl(C1-C3)alkenyl, di(C1-C3)alkylphosphonate, formen, (C1-C3)alkylcarbonyl, halo(C1-C3)alkylcarbonyl, (C1-C3)alkoxy(C1-C3)alkylcarbonyl, arylcarbonyl, and (C1-C3)alkylsulfonyl, -G is chosen from O, S, CH2O* and (CH2)n, where asterisk means attachment to E and n is an integer from 1, 2, and 3 that determines that E and G are neither O nor S at the same time. -x is an integer chosen from 0 or 1, where x is 1. -A is chosen from O, S(O)p, and -NR15, where p is an integer chosen from 0, 1, and 2, and R15 is as described above. -B is the linking group. *-(C16R17)q-(CR18R19)r-(CR20R21)s-Lt-(CR22R23)u-(CR24R25)v-(CR26R27)w-, where asterisks indicate attachments such that A, q, r, s, u, v, and w are integers freely selectable from 0, 1, and 2, and when q, r, s, u, v, or w is 1 or 2, R16 to R27 are freely selected from hydrogen, (C1-C3) alkyl, halo(C1-C3) alkyl, (C1-C3) al-koxy(C1-C3) alkyl, and (C3-C6) cycloalkyl, t is an integer freely selectable from 0 or 1, and when t is 1, L is selected from CH=CH, O, S(O)p, OS(O)2, S(O)2O, NR28, N(oxide)R28, NR28SO2, NR28, NR28C(=O)NR29, Si(CH3)2, C(=O), OC(=O), NHC(=O), ON=CH, HC=NO, C(=O)O, C(=O)NH, C(=NOR14) and [CR30R31]z, where p is as described above, R28 and R29 are independently selected from hydrogen, (C1-C3)alkyl, (C1-C3)alkylsulfonyl, (C1-C3)alkylcarbonyl, (C2-C5)alkenyl, and (C2-C5)alkinyl, z is an integer chosen from 1 or 2, and R30 and R31 are independently selected from hydrogen and (C1-C3)alkyl. -y is an integer chosen from 0 or 1, and where y is 1, -D is chosen. O, S(O)p, and NR15, where p and R15 are as described above, where D is attached to the fused ring segment. The ionic chains (R7, R8, R9, and R10) specified in formula I at any given position are 1- or 2-: (chemical formula) -R7, R8, R9, and R10 are chosen independently from hydrogen, halogens, (C1-C4)alkyl, (C3-C6)cycloalkyl, (C2-C5)alkinyl, (C2-C5)alkinyl, halo(C1-C4)alkyl, (C1-C4)alkoxy, halo(C1-C4)alkoxy, (C1-C4)alkylthio, halo(C1-C4)alkylthio, (C1-C4)alkylsulfonyl, halo(C1-C4)alkylsulfonyl, cyano, nitro, aryl, alkylcarbonylamino, arylcarbonylamino, and (C1-C4) alkoxycarbonylamino, M is selected from -CR32R33- and -CR32R33CR34R35-, and when M is -CR32R33-, R33 and R35 are selected independently from halogens, (C1-C3)alkyl, halo(C1-C3)alkyl, and (C1-C3)alkoxy(C1-C3)alkyl, and when M is -CR32R33CR34R35-, R32, R33, R34 and R35 are selected independently from hydrogen, halogens, (C1-C3)alkyl, halo(C1-C3)alkyl, and (C1-C3)alkoxy(C1-C3)alkyl and their agriculturally acceptable salts. 2. Compounds of claim 1 in which R and R3 are chosen independently of halogens and (C1-C3) alkyls, R1 and R2 are hydrogen, R5 and R6 are chosen independently of chlorine, bromine, and fluorine, E is O, G is (CH2)m, where n is 1, x is 1, and A is O, and when q, r, s, u, v, and w are 1 or 2, R16 to R27 are hydrogen, t is 0 or 1, and when t is 1, L is chosen from O, OC(=O), NHC(=O), ON=CH, and CH=NO, y is 1, and D is chosen from O, S(O)p, and NR15, where p is 0, and R5 is chosen from hydrogen, (C1-C3) alkyls, and aryls. (C1-C3)alkyl, (C2-C4)alkenyl, (C1-C3)alkyl, and halo(C2-C4)alkenyl(C1-C3)alkyl, where D is attached to the benzo-fused ring section clarified in formula I at the given position 1- or 2-, R7, R8, R9 and R10 are independently selected from hydrogen, halogen, halo(C1-C4)alkyl and nitro, where M is -CR32R33-, R32 and R33 are independently selected from halogen,(C1-C3)alkyl, and where M is -CR32R33CR34R35-, R32R33, R34 and R35 are independently selected from hydrogen, halogen, and (C1-C3)alkyl. 3. Compounds of claim 2 in which R and R3 are chosen independently from chlorine and methyl, R5 and R6 are chosen independently from chlorine and bromine, q, r, s, u, v, and w are 1 or 2, given that the positive of q, r, s, u, v, and w is at least 2 and at most 6, t is 0, D is O, R7, R8, R9, and R10 are chosen independently from hydrogen and hydrogen, and when M is -CR32R33-, R32 and R33 are chosen independently from fluorine and methyl, and when M is -CR32R33CR34R35-, R32, R33, R34, and R35 are chosen independently from hydrogen, fluorine, and methyl. 4. A compound of claim 3 where R, R3, R5, and R6 each are chlorine, q, r, and s are 1, u and v are 0 or 1, w is 0, and M is -CR32R33-, where R32 and R33 each are methyl. 5. Compounds of claim 3 in which R, R3, R5 and R6 are each chlorine, q, r and s are 1, u and v are 0 or 1, w is 0, M is -CR32R33CR34R35-, where R32, R33, R34 and R35 are chosen independently of hydrogen and fluorine. 6. The compound of claim 5, where D is attached to the benzo-fused portion clarified in formula I at design position 2, and R32, R33, R34, and R35 are each fluorinated. 7. Compounds of formula I: (chemical formula) I where -R and R3 are freely chosen from hydrogen, halogen, or (C1-C3)alkyl, -R1 and R2 are hydrogen, -E is O, G is (CH2)m, where n is 1, -R4 is hydrogen, -R5 and R6 are freely chosen from halogens, -x is 1, and A is O, and -B is the linking group. *-(C16R17)q-(CR18R19)r-(CR20R21)s-Lt-(CR22R23)u-(CR24R25)v-(CR26R27)w-, where asterisks indicate attachments where A, q, r, s, u, v, and w are freely selectable integers from 0, 1, and 2, and t is 0, and when q, r, s, u, v, or w is 1 or 2, R16 through R27 combined are hydrogen, -y is 1, and D is O, and where D is attached to the detached ring segment. Fused with benzoate clarified in formula I at any given position, designated 1- or 2-: (chemical formula) -R7, R8, R9, and R10 are independently selected from hydrogen, halogen, and (C1-C4)alkyl, -M is -CR32R33- where R32 and R33 are independently selected from halogen and (C1-C3)alkyl, and their agriculturally acceptable salts. 8. Compounds of claim 7 in which R and R3 are chosen independently from chlorine and methyl, R5 and R6 are chosen independently from chlorine and bromine, q, r, s, u, v, and w are 1 or 2, given that the positive of q, r, s, u, v, and w is at least 2 and at most 6, -R7, R8, R9, and R10 are chosen independently from hydrogen and halogen, and -R32 and R33 are chosen independently from fluorine and methyl. 9. Compounds of claim 8 where R, R3, R5 and R6 are each chlorine, q, r, and s are 1, u and v are 0 or 1, w is 0, and R32 and R33 are each methyl. 10. Compounds of formula I: (chemical formula) I where -R and R3 are chosen independently from hydrogen, halogens and (C1-C3)alkyl, -R1 and R2 are hydrogen, -E is O, G is (CH2)m, where n is 1, -R4 is hydrogen, -R5 and R6 are chosen independently from halogens, -x is 1, and A is O, and -B is the linking group. *-(C16R17)q-(CR18R19)r-(CR20R21)s-Lt-(CR22R23)u-(CR24R25)v-(CR26R27)w-, where asterisks indicate attachments where A, q, r, s, u, v, and w are freely selectable integers from 0, 1, and 2, and t is 0, and when q, r, s, u, v, or w is 1 or 2, R16 through R27 combined are hydrogen, -y is 1, and D is O, and where D is attached to the detached ring segment. Fused with benzoate clarified in formula I at any one of the designated 1- or 2- positions: (chemical formula) where -R7, R8, R9, and R10 are freely chosen from hydrogen, halogens, and (C1-C4) alkyls, -M is -CR32R33CR34R35-, where R32, R33, R34, and R35 are freely chosen from hydrogen, halogens, and (C1-C3) alkyls, and their agriculturally acceptable salts. 11. Compounds of claim 10 where R and R3 are independently selected from chlorine and methyl, R5 and R6 are independently selected from chlorine and bromine, q, r, s, u, v, and w are 0, 1, or 2, given that the positive of q, r, s, u, v, and w is at least 2 and at most 6, -R7, R8, R9, and R10 are independently selected from hydrogen and halogen, and -R32, R33, R34, and R35 are independently selected from hydrogen, fluorine, and methyl. 12. Compounds of claim 11 where R, R3, R5, and R6 are each chlorine, q, r, and s are 1, u and v are 0 or 1, w is 0, and -R32, R33, R34, and R35 are chosen independently of hydrogen and fluorine. 13. The compound of claim 12, where D is attached to the benzo-fused portion clarified in formula I at position 2, and R32, R33, R34, and R35 are each fluorine. 14. A mixture containing insecticidal quantities of the compounds of claim I in an original mixture containing at least one agriculturally acceptable bulking or excipient. 15. An insecticide mixture of claim 14 which includes one or more selected second compounds from a group of pesticides, plant growth regulators, fertilizers and soil conditioners. 16. Methods of insect control consisting of the application of insecticidal quantities of the mixture of claims in Article 14 to locations where insects are present or are expected to be present. 17. Methods of insect control consisting of the application of insecticidal quantities of the mixture of claims in Article 15 to locations where insects are present or are expected to be present.