TH780A - Pharmaceutical carriers and mixtures (processes) - Google Patents

Abstract

The pharmaceutical carrier, or excipient, consists of solid milk and tripotassium phosphate. This is particularly suitable for preparing mixtures containing moisture-sensitive, potentially acidic components. It is especially well-suited for mixing with acelylsalicylic acid (ASA) to facilitate rapid dispersion of the components in water. The resulting solution is a buffer and contains neutralized ASA dissolved in liquid milk.

Claims (4)

1. Process for preparing mixtures of ASA (acetylsalicylic acid), which consists of ASA and milk in solid state, which in contact with water will disperse rapidly. Neutral ASA buffer pattern in the connected fluid cycle. It is characterized by having sufficient amounts of trypotassium phosphate that (1) neutralizes ASA and (2) combines with the moisture contained in milk in the Solids where the process consists of 3 to 20 parts solid milk by weight per portion By weight per all other components, including And which contains at least 0.5 mL of trypotassium phosphate per mole of ASA. This process is unique in that the first pre-mixed compound contains trypotassium phosphate and one portion. Milk in All solid state The second batch contains ASA and the other part of the whole milk solid state. After that, the first and second mixtures are mixed. With remaining solid milk, the moisture content of milk in The solid state used is between 2 and 4% by weight. 2. Process according to claim No. 1, which is a substance that has been mixed before the first batch There is at least one flavoring, sweetener, and color. 3. Process according to claim 1 or item 2, milk teeth in the premises Solid is whey powder 4. Process according to Clause 1, 2 or 3 of any of the above Which calls potassium phosphate The particle size is not more than 100 micrometers (4 claims, 1 page, 0 pictures).