TH79014B - P analogues for the treatment of cancer - Google Patents
P analogues for the treatment of cancerInfo
- Publication number
- TH79014B TH79014B TH101001978A TH0101001978A TH79014B TH 79014 B TH79014 B TH 79014B TH 101001978 A TH101001978 A TH 101001978A TH 0101001978 A TH0101001978 A TH 0101001978A TH 79014 B TH79014 B TH 79014B
- Authority
- TH
- Thailand
- Prior art keywords
- peptides
- trp
- phe
- cancer treatment
- cancer
- Prior art date
Links
- 206010028980 Neoplasm Diseases 0.000 title abstract 3
- 201000011510 cancer Diseases 0.000 title abstract 3
- 108090000765 processed proteins & peptides Proteins 0.000 claims abstract 9
- 102000004196 processed proteins & peptides Human genes 0.000 claims abstract 8
- 125000000218 acetic acid group Chemical group C(C)(=O)* 0.000 claims 1
- 125000002252 acyl group Chemical group 0.000 claims 1
- 125000004429 atom Chemical group 0.000 claims 1
- 125000004432 carbon atom Chemical group C* 0.000 claims 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 claims 1
- 150000003839 salts Chemical class 0.000 claims 1
- 239000005557 antagonist Substances 0.000 abstract 2
- 150000001413 amino acids Chemical class 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 230000000144 pharmacologic effect Effects 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
Abstract
การประดิษฐ์นี้ครอบคลุมอะนาลอกเพพไทด์ที่สังเคราะห์ใหม่ซึ่งเป็นตัวต้านฤทธิ์ต่อสาร P เพพไทด์ที่คล้ายสาร P และเพพไทด์ที่เกี่ยวข้องกันและเป็นประโยชน์สำหรับการรักษามะเร็ง การ ประดิษฐ์เกี่ยวข้องโดยเฉพาะอย่างยิ่งกับการออกแบบและสังเคราะห์อนาลอกตัวต้านฤทธิ์สาร P ที่ ใหม่ที่รวมกรดอะมิโนแอลฟา, แอลฟา-ไดอัลคิเลทเตทในรูปแบบที่จำเพาะต่อตำแหน่ง การประดิษฐ์ ครอบคลุมวิธีสำหรับการสร้างเพพไทด์เหล่านี้ สารผสมที่มีเพพไทด์เหล่านี้และการใช้ทางเภสัชของ เพพไทด์เหล่านี้โดยเฉพาะอย่างยิ่งในการรักษาและการป้องกันมะเร็ง The invention encompasses newly synthesized peptide analogs that are antagonists against P, P-like peptides and related peptides and are useful for cancer treatment. This is especially true for the design and synthesis of a new P-antagonist analogue combining amino acids, α-dialkylatedates, in a location-specific format. The fabrication covers a method for making peptides. These Mixtures containing these peptides and their pharmacological uses These peptides are especially common in cancer treatment and prevention.
Claims (2)
Publications (2)
| Publication Number | Publication Date |
|---|---|
| TH79014B true TH79014B (en) | 2006-08-03 |
| TH79014A TH79014A (en) | 2006-08-03 |
Family
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