TJ272B - Quinazoline compounds or their pharmaceutical acceptable salts and pharmaceutical composition - Google Patents

Quinazoline compounds or their pharmaceutical acceptable salts and pharmaceutical composition

Info

Publication number
TJ272B
TJ272B TJ96000367A TJ96000367A TJ272B TJ 272 B TJ272 B TJ 272B TJ 96000367 A TJ96000367 A TJ 96000367A TJ 96000367 A TJ96000367 A TJ 96000367A TJ 272 B TJ272 B TJ 272B
Authority
TJ
Tajikistan
Prior art keywords
compounds
quinazoline compounds
pharmaceutical
acceptable salts
pharmaceutical composition
Prior art date
Application number
TJ96000367A
Other languages
English (en)
Inventor
Stephen Webber
Ted M Bleckman
John Attard
Terence R Jones
Michael D Varney
Original Assignee
Agouron Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Agouron Pharma filed Critical Agouron Pharma
Publication of TJ272B publication Critical patent/TJ272B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/86—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
    • C07D239/88—Oxygen atoms
    • C07D239/90—Oxygen atoms with acyclic radicals attached in position 2 or 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/86—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
    • C07D239/93—Sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/95—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in positions 2 and 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
TJ96000367A 1992-03-31 1993-03-26 Quinazoline compounds or their pharmaceutical acceptable salts and pharmaceutical composition TJ272B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/861,030 US5430148A (en) 1992-03-31 1992-03-31 Antiproliferative quinazolines
PCT/US1993/002636 WO1993020055A1 (fr) 1992-03-31 1993-03-26 Quinazolines anti-proliferatives

Publications (1)

Publication Number Publication Date
TJ272B true TJ272B (en) 2000-10-05

Family

ID=25334675

Family Applications (1)

Application Number Title Priority Date Filing Date
TJ96000367A TJ272B (en) 1992-03-31 1993-03-26 Quinazoline compounds or their pharmaceutical acceptable salts and pharmaceutical composition

Country Status (20)

Country Link
US (3) US5430148A (fr)
EP (1) EP0637300B1 (fr)
JP (1) JP3272357B2 (fr)
KR (1) KR100226114B1 (fr)
AT (1) ATE205197T1 (fr)
AU (1) AU681075B2 (fr)
CA (2) CA2132514C (fr)
DE (1) DE69330715T2 (fr)
DK (1) DK0637300T3 (fr)
ES (1) ES2162818T3 (fr)
FI (1) FI113765B (fr)
HU (1) HU222523B1 (fr)
MD (1) MD1638G2 (fr)
NO (1) NO307829B1 (fr)
NZ (1) NZ251804A (fr)
PT (1) PT637300E (fr)
RU (1) RU2135481C1 (fr)
SG (2) SG46672A1 (fr)
TJ (1) TJ272B (fr)
WO (1) WO1993020055A1 (fr)

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RU2205831C2 (ru) * 1997-04-25 2003-06-10 Янссен Фармацевтика Н.В. Хиназолиноны, ингибирующие фарнезилтрансферазу
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WO1999008110A1 (fr) * 1997-08-08 1999-02-18 Newbiotics, Inc. Methodes et compositions pour surmonter la resistance a une therapie biologique et a une chimiotherapie
IL137164A0 (en) 1998-01-23 2001-07-24 Newbiotics Inc Enzyme catalyzed therapeutic agents
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US6906205B2 (en) * 2002-06-21 2005-06-14 Medicines For Malaria Venture Mmv Spiro and dispiro 1,2,4-trioxolane antimalarials
EP1537089A4 (fr) * 2002-07-23 2008-04-16 Cytokinetics Inc Composes, compositions et procedes
WO2004018058A2 (fr) * 2002-08-21 2004-03-04 Cytokinetics, Inc. Composes, compositions et methodes
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WO2005032481A2 (fr) * 2003-09-30 2005-04-14 Scios Inc. Dérivés de quinazoline en tant que médicaments
WO2005041888A2 (fr) * 2003-11-03 2005-05-12 Cytokinetics, Inc. Composes, compositions et methodes
JP2007510660A (ja) * 2003-11-07 2007-04-26 サイトキネティクス・インコーポレーテッド 化合物、組成物及び方法
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Also Published As

Publication number Publication date
FI944525L (fi) 1994-09-29
AU681075B2 (en) 1997-08-21
MD1638G2 (ro) 2001-09-30
US5430148A (en) 1995-07-04
DK0637300T3 (da) 2001-12-10
EP0637300A1 (fr) 1995-02-08
SG93183A1 (en) 2002-12-17
HU9402799D0 (en) 1994-12-28
DE69330715T2 (de) 2002-02-14
NO943629L (no) 1994-09-29
PT637300E (pt) 2002-01-30
WO1993020055A1 (fr) 1993-10-14
CA2474211A1 (fr) 1993-10-14
DE69330715D1 (de) 2001-10-11
US5707992A (en) 1998-01-13
CA2132514C (fr) 2004-10-26
NZ251804A (en) 1997-06-24
RU94045251A (ru) 1996-07-20
NO943629D0 (no) 1994-09-29
CA2474211C (fr) 2006-10-03
JP3272357B2 (ja) 2002-04-08
ATE205197T1 (de) 2001-09-15
HU222523B1 (hu) 2003-08-28
HUT68580A (en) 1995-06-28
ES2162818T3 (es) 2002-01-16
CA2132514A1 (fr) 1993-10-14
NO307829B1 (no) 2000-06-05
US5885996A (en) 1999-03-23
JPH07505395A (ja) 1995-06-15
SG46672A1 (en) 1998-02-20
KR100226114B1 (ko) 1999-10-15
FI113765B (fi) 2004-06-15
MD1638F2 (en) 2001-03-31
AU3966493A (en) 1993-11-08
FI944525A0 (fi) 1994-09-29
RU2135481C1 (ru) 1999-08-27
EP0637300B1 (fr) 2001-09-05

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