TR199900733T2 - Patojenik organizmalar ile nasofarinksin kolonizasyonu ile ilgili bakteriyal enfeksiyonlarin tedavisi için bir ilacin imalatinda mupirosin kullanimi. - Google Patents
Patojenik organizmalar ile nasofarinksin kolonizasyonu ile ilgili bakteriyal enfeksiyonlarin tedavisi için bir ilacin imalatinda mupirosin kullanimi.Info
- Publication number
- TR199900733T2 TR199900733T2 TR1999/00733T TR9900733T TR199900733T2 TR 199900733 T2 TR199900733 T2 TR 199900733T2 TR 1999/00733 T TR1999/00733 T TR 1999/00733T TR 9900733 T TR9900733 T TR 9900733T TR 199900733 T2 TR199900733 T2 TR 199900733T2
- Authority
- TR
- Turkey
- Prior art keywords
- mupirocin
- nasopharynx
- treatment
- colonization
- medicament
- Prior art date
Links
- MINDHVHHQZYEEK-UHFFFAOYSA-N (E)-(2S,3R,4R,5S)-5-[(2S,3S,4S,5S)-2,3-epoxy-5-hydroxy-4-methylhexyl]tetrahydro-3,4-dihydroxy-(beta)-methyl-2H-pyran-2-crotonic acid ester with 9-hydroxynonanoic acid Natural products CC(O)C(C)C1OC1CC1C(O)C(O)C(CC(C)=CC(=O)OCCCCCCCCC(O)=O)OC1 MINDHVHHQZYEEK-UHFFFAOYSA-N 0.000 title abstract 2
- 229960003128 mupirocin Drugs 0.000 title abstract 2
- 229930187697 mupirocin Natural products 0.000 title abstract 2
- DDHVILIIHBIMQU-YJGQQKNPSA-L mupirocin calcium hydrate Chemical compound O.O.[Ca+2].C[C@H](O)[C@H](C)[C@@H]1O[C@H]1C[C@@H]1[C@@H](O)[C@@H](O)[C@H](C\C(C)=C\C(=O)OCCCCCCCCC([O-])=O)OC1.C[C@H](O)[C@H](C)[C@@H]1O[C@H]1C[C@@H]1[C@@H](O)[C@@H](O)[C@H](C\C(C)=C\C(=O)OCCCCCCCCC([O-])=O)OC1 DDHVILIIHBIMQU-YJGQQKNPSA-L 0.000 title abstract 2
- 210000001989 nasopharynx Anatomy 0.000 title abstract 2
- 208000035143 Bacterial infection Diseases 0.000 title 1
- 208000022362 bacterial infectious disease Diseases 0.000 title 1
- 239000003814 drug Substances 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 244000052769 pathogen Species 0.000 title 1
- 208000005141 Otitis Diseases 0.000 abstract 1
- 208000019258 ear infection Diseases 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 230000000306 recurrent effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 201000009890 sinusitis Diseases 0.000 abstract 1
- 239000007921 spray Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0043—Nose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/351—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom not condensed with another ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Otolaryngology (AREA)
- Oncology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Communicable Diseases (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Mupirosin veya bunun tuz veya esteri, özellikle de nazofarenkse uygulanmak üzere uyarlanmis olan yeni bir sprey veya terkipleri ile nükseden sinüzit ve nükseden otitin tedavisi için kullanilabilir.
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US2722296P | 1996-10-01 | 1996-10-01 | |
| US2722496P | 1996-10-01 | 1996-10-01 | |
| US2722396P | 1996-10-01 | 1996-10-01 | |
| GBGB9716805.8A GB9716805D0 (en) | 1997-08-09 | 1997-08-09 | Novel composition and use |
| GBGB9719203.3A GB9719203D0 (en) | 1997-09-11 | 1997-09-11 | Novel composition and use |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TR199900733T2 true TR199900733T2 (tr) | 1999-07-21 |
Family
ID=27517419
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TR1999/00733T TR199900733T2 (tr) | 1996-10-01 | 1997-09-29 | Patojenik organizmalar ile nasofarinksin kolonizasyonu ile ilgili bakteriyal enfeksiyonlarin tedavisi için bir ilacin imalatinda mupirosin kullanimi. |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US6001870A (tr) |
| EP (1) | EP0939631A1 (tr) |
| JP (1) | JP2001504091A (tr) |
| KR (1) | KR20000048812A (tr) |
| CN (1) | CN1239427A (tr) |
| AR (1) | AR010995A1 (tr) |
| AU (1) | AU724070B2 (tr) |
| BR (1) | BR9711843A (tr) |
| CA (1) | CA2267248A1 (tr) |
| CZ (1) | CZ112499A3 (tr) |
| HU (1) | HUP9904308A3 (tr) |
| IL (1) | IL129237A0 (tr) |
| NO (1) | NO991548L (tr) |
| NZ (1) | NZ334913A (tr) |
| PL (1) | PL332642A1 (tr) |
| TR (1) | TR199900733T2 (tr) |
| WO (1) | WO1998014189A1 (tr) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CO4910145A1 (es) * | 1996-10-01 | 2000-04-24 | Smithkline Beecham Corp | Uso |
| WO1998014189A1 (en) * | 1996-10-01 | 1998-04-09 | Smithkline Beecham Corporation | Use of mupirocin for the manufacture of a medicament for the treatment of bacterial infections associated with colonisation of the nasopharynx by pathogenic organisms |
| WO1999007341A1 (en) * | 1997-08-09 | 1999-02-18 | Smithkline Beecham Plc | Compositions for nasal administration |
| UY25225A1 (es) | 1997-10-29 | 2000-12-29 | Smithkline Beecham Plc | Derivados de pleuromutilina utiles como agentes antimicrobianos |
| GB9808470D0 (en) | 1998-04-22 | 1998-06-17 | Smithkline Beecham Plc | Novel process and apparatus |
| GB9902138D0 (en) | 1999-02-02 | 1999-03-24 | Smithkline Beecham | Container |
| HRP20010576A2 (en) * | 1999-02-03 | 2002-08-31 | Biogal Gyogyszergyar | Process for the preparation of pseudomonic acid a antibiotic by microbiological method |
| WO2000074651A1 (de) * | 1999-06-02 | 2000-12-14 | Hexal Ag | Pharmazeutische zusammensetzung zur nasalen anwendung von wasserunlöslichen und/oder schwer wasserlöslichen wirkstoffen |
| US6156294A (en) * | 1999-11-28 | 2000-12-05 | Scientific Development And Research, Inc. | Composition and method for treatment of otitis media |
| US6676930B2 (en) | 1999-11-28 | 2004-01-13 | Scientific Development And Research, Inc. | Composition and method for treatment of otitis media |
| EP1409703A4 (en) * | 2001-06-21 | 2004-08-18 | Biogal Gyogyszergyar | METABOLICALLY CONTROLLED FERMENTATION PROCESS FOR THE PRODUCTION OF PSEUDOMONIC ACID |
| HRP20040642A2 (en) | 2001-12-28 | 2005-10-31 | Teva Gy�gyszergy�r R�szv�nyt�rsas�g | Processes for preparing crystalline and amorphous mupirocin calcium |
| US20050058673A1 (en) | 2003-09-09 | 2005-03-17 | 3M Innovative Properties Company | Antimicrobial compositions and methods |
| US7589128B2 (en) * | 2004-06-01 | 2009-09-15 | Teva Gyógyszergyár Zártkörüen Müködö Részvénytársaság | Process for preparation of amorphous form of a drug |
| JP2008533048A (ja) * | 2005-03-10 | 2008-08-21 | スリーエム イノベイティブ プロパティズ カンパニー | 耳の感染症の治療方法 |
| EP2497460A1 (en) | 2005-03-10 | 2012-09-12 | 3M Innovative Properties Co. | Methods of reducing microbial contamination |
| KR20070113281A (ko) | 2005-03-10 | 2007-11-28 | 쓰리엠 이노베이티브 프로퍼티즈 컴파니 | 항미생물성 조성물 및 방법 |
| GB2437488A (en) * | 2006-04-25 | 2007-10-31 | Optinose As | Pharmaceutical oily formulation for nasal or buccal administration |
| US7993675B2 (en) | 2006-05-10 | 2011-08-09 | Medtronic Xomed, Inc. | Solvating system and sealant for medical use in the sinuses and nasal passages |
| US7959943B2 (en) | 2006-05-10 | 2011-06-14 | Medtronics Xomed, Inc. | Solvating system and sealant for medical use in the middle or inner ear |
| US7976873B2 (en) | 2006-05-10 | 2011-07-12 | Medtronic Xomed, Inc. | Extracellular polysaccharide solvating system for treatment of bacterial ear conditions |
| US20070264296A1 (en) | 2006-05-10 | 2007-11-15 | Myntti Matthew F | Biofilm extracellular polysachharide solvating system |
| US8088095B2 (en) | 2007-02-08 | 2012-01-03 | Medtronic Xomed, Inc. | Polymeric sealant for medical use |
| US8784790B2 (en) | 2008-06-12 | 2014-07-22 | Medtronic Xomed, Inc. | Method for treating chronic wounds with an extracellular polymeric substance solvating system |
| US20100021563A1 (en) * | 2008-07-24 | 2010-01-28 | Paul Levesque | Compositions comprising coconut oil and methods of use thereof |
| US20100086576A1 (en) | 2008-10-06 | 2010-04-08 | Myntti Matthew F | Antimicrobial composition and methods of making and using same |
| US10653133B2 (en) | 2011-05-10 | 2020-05-19 | Next Science IP Holdings Pty Ltd | Antimicrobial solid and methods of making and using same |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ200918A (en) * | 1981-07-02 | 1985-07-31 | Gist Brocades Nv | Stable fatty oil-in-water emulsion cream for topical application |
| CA1196284A (en) * | 1982-05-28 | 1985-11-05 | Joshua Oduro-Yeboah | Pharmaceutical formulations |
| SE8206744D0 (sv) * | 1982-11-26 | 1982-11-26 | Fluidcarbon International Ab | Preparat for kontrollerad avgivning av substanser |
| GB8415579D0 (en) * | 1984-06-19 | 1984-07-25 | Beecham Group Plc | Compounds |
| GB8530796D0 (en) * | 1985-12-13 | 1986-01-22 | Beecham Group Plc | Pharmaceutical composition |
| IE59628B1 (en) * | 1986-06-26 | 1994-03-09 | Beecham Group Plc | Treatment of fungal infections |
| US5594026A (en) * | 1990-12-11 | 1997-01-14 | Smithkline Beecham Group P.L.C. | Polymorphs of crystalline mupirocin |
| CN1102410C (zh) * | 1993-10-22 | 2003-03-05 | 史密丝克莱恩比彻姆公司 | 莫匹罗星钙盐的乳膏组合物 |
| WO1998014189A1 (en) * | 1996-10-01 | 1998-04-09 | Smithkline Beecham Corporation | Use of mupirocin for the manufacture of a medicament for the treatment of bacterial infections associated with colonisation of the nasopharynx by pathogenic organisms |
-
1997
- 1997-09-29 WO PCT/GB1997/002664 patent/WO1998014189A1/en not_active Ceased
- 1997-09-29 CN CN97180242A patent/CN1239427A/zh active Pending
- 1997-09-29 EP EP97943966A patent/EP0939631A1/en not_active Withdrawn
- 1997-09-29 PL PL97332642A patent/PL332642A1/xx unknown
- 1997-09-29 HU HU9904308A patent/HUP9904308A3/hu unknown
- 1997-09-29 JP JP51631398A patent/JP2001504091A/ja active Pending
- 1997-09-29 TR TR1999/00733T patent/TR199900733T2/tr unknown
- 1997-09-29 CZ CZ991124A patent/CZ112499A3/cs unknown
- 1997-09-29 IL IL12923797A patent/IL129237A0/xx unknown
- 1997-09-29 CA CA002267248A patent/CA2267248A1/en not_active Abandoned
- 1997-09-29 NZ NZ334913A patent/NZ334913A/en unknown
- 1997-09-29 BR BR9711843-5A patent/BR9711843A/pt not_active IP Right Cessation
- 1997-09-29 AU AU45623/97A patent/AU724070B2/en not_active Ceased
- 1997-09-29 KR KR1019990702807A patent/KR20000048812A/ko not_active Withdrawn
- 1997-09-30 AR ARP970104497A patent/AR010995A1/es unknown
- 1997-09-30 US US08/940,730 patent/US6001870A/en not_active Expired - Fee Related
-
1999
- 1999-03-30 NO NO991548A patent/NO991548L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| NZ334913A (en) | 2001-03-30 |
| JP2001504091A (ja) | 2001-03-27 |
| HUP9904308A3 (en) | 2002-06-28 |
| EP0939631A1 (en) | 1999-09-08 |
| HUP9904308A2 (hu) | 2001-04-28 |
| WO1998014189A1 (en) | 1998-04-09 |
| NO991548L (no) | 1999-03-31 |
| BR9711843A (pt) | 2001-07-31 |
| PL332642A1 (en) | 1999-09-27 |
| NO991548D0 (no) | 1999-03-30 |
| CN1239427A (zh) | 1999-12-22 |
| CA2267248A1 (en) | 1998-04-09 |
| AU4562397A (en) | 1998-04-24 |
| AU724070B2 (en) | 2000-09-14 |
| US6001870A (en) | 1999-12-14 |
| AR010995A1 (es) | 2000-08-02 |
| CZ112499A3 (cs) | 1999-08-11 |
| IL129237A0 (en) | 2000-02-17 |
| KR20000048812A (ko) | 2000-07-25 |
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