TR200000734T2 - Seçici bir 5-HT1A/5-HT1B antagonistinin veya kısmi antagonistinin bir bileşimi. - Google Patents
Seçici bir 5-HT1A/5-HT1B antagonistinin veya kısmi antagonistinin bir bileşimi.Info
- Publication number
- TR200000734T2 TR200000734T2 TR2000/00734T TR200000734T TR200000734T2 TR 200000734 T2 TR200000734 T2 TR 200000734T2 TR 2000/00734 T TR2000/00734 T TR 2000/00734T TR 200000734 T TR200000734 T TR 200000734T TR 200000734 T2 TR200000734 T2 TR 200000734T2
- Authority
- TR
- Turkey
- Prior art keywords
- antagonist
- ht1a
- selective
- composition
- ht1b
- Prior art date
Links
- 102100022738 5-hydroxytryptamine receptor 1A Human genes 0.000 title 1
- 101710138638 5-hydroxytryptamine receptor 1A Proteins 0.000 title 1
- 239000005557 antagonist Substances 0.000 title 1
- 239000003727 serotonin 1A antagonist Substances 0.000 title 1
- 239000004000 serotonin 1B antagonist Substances 0.000 title 1
- 125000001995 cyclobutyl group Chemical group [H]C1([H])C([H])([H])C([H])(*)C1([H])[H] 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- 125000000484 butyl group Chemical group [H]C([*])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 abstract 1
- 125000000113 cyclohexyl group Chemical group [H]C1([H])C([H])([H])C([H])([H])C([H])(*)C([H])([H])C1([H])[H] 0.000 abstract 1
- 125000001511 cyclopentyl group Chemical group [H]C1([H])C([H])([H])C([H])([H])C([H])(*)C1([H])[H] 0.000 abstract 1
- 125000001449 isopropyl group Chemical group [H]C([H])([H])C([H])(*)C([H])([H])[H] 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 125000004123 n-propyl group Chemical group [H]C([H])([H])C([H])([H])C([H])([H])* 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Bulus, formül (I)'e sahip olan ki bu formülde, R1 n-propil veya siklobutildir, R2 izopropil, tersiyer butil, siklobutil, siklopentil veya siklohekzildir, R3 hidrojen ve R4 hidrojen ya da metildir ve (R)-enantiyomeri seklindedir.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE9703374A SE9703374D0 (sv) | 1997-09-18 | 1997-09-18 | A new combination |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TR200000734T2 true TR200000734T2 (tr) | 2000-11-21 |
Family
ID=20408294
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TR2000/00734T TR200000734T2 (tr) | 1997-09-18 | 1998-09-09 | Seçici bir 5-HT1A/5-HT1B antagonistinin veya kısmi antagonistinin bir bileşimi. |
Country Status (29)
| Country | Link |
|---|---|
| US (1) | US6159972A (tr) |
| EP (1) | EP1021183B1 (tr) |
| JP (1) | JP2001516717A (tr) |
| KR (1) | KR20010024075A (tr) |
| CN (1) | CN1182847C (tr) |
| AR (1) | AR015447A1 (tr) |
| AT (1) | ATE261728T1 (tr) |
| AU (1) | AU752718B2 (tr) |
| BR (1) | BR9812234A (tr) |
| CA (1) | CA2302383A1 (tr) |
| DE (1) | DE69822490T2 (tr) |
| DK (1) | DK1021183T3 (tr) |
| EE (1) | EE04142B1 (tr) |
| ES (1) | ES2216307T3 (tr) |
| HU (1) | HUP0100401A3 (tr) |
| IL (1) | IL134774A0 (tr) |
| IS (1) | IS5408A (tr) |
| MY (1) | MY116281A (tr) |
| NO (1) | NO20001398L (tr) |
| NZ (1) | NZ503174A (tr) |
| PL (1) | PL339370A1 (tr) |
| PT (1) | PT1021183E (tr) |
| RU (1) | RU2215528C2 (tr) |
| SE (1) | SE9703374D0 (tr) |
| SK (1) | SK2842000A3 (tr) |
| TR (1) | TR200000734T2 (tr) |
| TW (1) | TW568786B (tr) |
| WO (1) | WO1999013876A1 (tr) |
| ZA (1) | ZA987810B (tr) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE9601110D0 (sv) * | 1996-03-22 | 1996-03-22 | Astra Ab | Substituted 1,2,3,4-tetrahydronaphthalene derivatives |
| SE9703375D0 (sv) * | 1997-09-18 | 1997-09-18 | Astra Ab | A new combination |
| WO2002066454A1 (fr) * | 2001-02-21 | 2002-08-29 | Sankyo Company, Limited | Derives de chromene |
| DK1408976T5 (da) * | 2001-07-20 | 2011-01-10 | Psychogenics Inc | Behandling af ADHD (Attention deficit hyperactivity disorder) |
| US20050165025A1 (en) * | 2004-01-22 | 2005-07-28 | Recordati Ireland Ltd. | Combination therapy with 5HT 1A and 5HT 1B-receptor antagonists |
| USD969017S1 (en) | 2021-06-28 | 2022-11-08 | Koninklijke Asscher Diamant Maatschappij B.V. | Rose marquise diamond article |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ZA90673B (en) * | 1989-02-02 | 1990-10-31 | Yamanouchi Pharma Co Ltd | Tetrahydrobenzimidazole derivatives |
| ES2162792T3 (es) * | 1991-09-18 | 2002-01-16 | Glaxo Group Ltd | Derivados de benzanilida como antagonistas de 5-ht1d. |
| GB9410512D0 (en) * | 1994-05-25 | 1994-07-13 | Smithkline Beecham Plc | Novel treatment |
| SE9501567D0 (sv) * | 1995-04-27 | 1995-04-27 | Astra Ab | A new combination |
| FI961247A0 (fi) * | 1996-03-18 | 1996-03-18 | Finnish Peroxides Ab Oy | Foerfarande foer loesning av uppsvaellningsproblem i en avfalls vattenreningsanordning foer kontroll av traodartiga bakterier |
| SE9601110D0 (sv) * | 1996-03-22 | 1996-03-22 | Astra Ab | Substituted 1,2,3,4-tetrahydronaphthalene derivatives |
-
1997
- 1997-09-18 SE SE9703374A patent/SE9703374D0/xx unknown
-
1998
- 1998-08-27 ZA ZA987810A patent/ZA987810B/xx unknown
- 1998-08-29 TW TW087114345A patent/TW568786B/zh not_active IP Right Cessation
- 1998-09-09 US US09/171,581 patent/US6159972A/en not_active Expired - Fee Related
- 1998-09-09 CA CA002302383A patent/CA2302383A1/en not_active Abandoned
- 1998-09-09 TR TR2000/00734T patent/TR200000734T2/tr unknown
- 1998-09-09 AU AU91929/98A patent/AU752718B2/en not_active Ceased
- 1998-09-09 AT AT98944374T patent/ATE261728T1/de not_active IP Right Cessation
- 1998-09-09 ES ES98944374T patent/ES2216307T3/es not_active Expired - Lifetime
- 1998-09-09 RU RU2000109558/14A patent/RU2215528C2/ru not_active IP Right Cessation
- 1998-09-09 WO PCT/SE1998/001600 patent/WO1999013876A1/en not_active Ceased
- 1998-09-09 DK DK98944374T patent/DK1021183T3/da active
- 1998-09-09 HU HU0100401A patent/HUP0100401A3/hu unknown
- 1998-09-09 NZ NZ503174A patent/NZ503174A/en unknown
- 1998-09-09 PT PT98944374T patent/PT1021183E/pt unknown
- 1998-09-09 EE EEP200000143A patent/EE04142B1/xx not_active IP Right Cessation
- 1998-09-09 SK SK284-2000A patent/SK2842000A3/sk unknown
- 1998-09-09 CN CNB988112493A patent/CN1182847C/zh not_active Expired - Fee Related
- 1998-09-09 BR BR9812234-7A patent/BR9812234A/pt not_active IP Right Cessation
- 1998-09-09 IL IL13477498A patent/IL134774A0/xx unknown
- 1998-09-09 KR KR1020007002821A patent/KR20010024075A/ko not_active Ceased
- 1998-09-09 PL PL98339370A patent/PL339370A1/xx unknown
- 1998-09-09 JP JP2000511498A patent/JP2001516717A/ja active Pending
- 1998-09-09 DE DE69822490T patent/DE69822490T2/de not_active Expired - Fee Related
- 1998-09-09 EP EP98944374A patent/EP1021183B1/en not_active Expired - Lifetime
- 1998-09-16 MY MYPI98004226A patent/MY116281A/en unknown
- 1998-09-17 AR ARP980104633A patent/AR015447A1/es unknown
-
2000
- 2000-03-15 IS IS5408A patent/IS5408A/is unknown
- 2000-03-17 NO NO20001398A patent/NO20001398L/no not_active Application Discontinuation
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE218859T1 (de) | Liganden des neuropeptids y | |
| TR199902946T2 (tr) | Türetilmis 3-siyano kinolinler. | |
| NL350077I1 (nl) | Cyprosulfamide | |
| DK0892780T3 (da) | m-Amidinophenylanaloger som faktor Xa-inhibitorer | |
| MY136789A (en) | Metalloproteinase inhibitors | |
| DE59903442D1 (de) | Azidfreie, gaserzeugende Zusammensetzung | |
| SI1392642T1 (sl) | Nove spojine kot protivnetna, imunomodulacijska in antiproliferativna sredstva | |
| DK1040108T3 (da) | Orthoanthranilamidderivater som antikoagulanter | |
| SE0004245D0 (sv) | Novel compounds and their use | |
| TR200002320T2 (tr) | Sert termoplastik poliüretan içeren bileşimlerden elastomerler. | |
| TR199801866A1 (tr) | Yeni piperazin ve piperidin bilesikleri | |
| TR200201613T2 (tr) | Antitümör tesirli 2-(1H-indol-3-il)-2-okso asetamidler | |
| ATE318810T1 (de) | 3-oxadiazol-5-yl-1-aminoalkyl-1h-indolderivate | |
| TR200201128T2 (tr) | PDE4 inhibitörleri olarak tetrahidrotiyopiranfitalazinon türevleri. | |
| TR200000734T2 (tr) | Seçici bir 5-HT1A/5-HT1B antagonistinin veya kısmi antagonistinin bir bileşimi. | |
| BR9902084A (pt) | Heterociclos. | |
| DK1204659T3 (da) | Serotonerge benzofuraner | |
| BG105539A (bg) | Елетриптан хидробромид монохидрат | |
| ATE287403T1 (de) | 6-phenylbenzonaphthyidine | |
| MXPA02011234A (es) | Nuevas bases de oxidacion 2,5-diaminopiridina utiles para el tinte de las fibras queratinicas. | |
| BR9907426A (pt) | Tetrahidronaftalenos | |
| TR200402754T4 (tr) | Yeni benzosultam oksazolidinon antibakteriyel maddeler. | |
| TR200002755T2 (tr) | Aracı hazırlamak için süreç. | |
| ATE213236T1 (de) | Substituierte benzyloxyimino-verbindungen | |
| TR200003203T2 (tr) | Karboksaldehitin saflaştırılması |