TR200003250T2 - Higromisin A türevleri - Google Patents
Higromisin A türevleriInfo
- Publication number
- TR200003250T2 TR200003250T2 TR2000/03250T TR200003250T TR200003250T2 TR 200003250 T2 TR200003250 T2 TR 200003250T2 TR 2000/03250 T TR2000/03250 T TR 2000/03250T TR 200003250 T TR200003250 T TR 200003250T TR 200003250 T2 TR200003250 T2 TR 200003250T2
- Authority
- TR
- Turkey
- Prior art keywords
- compounds
- formula
- infections
- hygromycin
- derivatives
- Prior art date
Links
- YQYJSBFKSSDGFO-FWAVGLHBSA-N hygromycin A Chemical class O[C@H]1[C@H](O)[C@H](C(=O)C)O[C@@H]1Oc1ccc(\C=C(/C)C(=O)N[C@@H]2[C@@H]([C@H]3OCO[C@H]3[C@@H](O)[C@@H]2O)O)cc1O YQYJSBFKSSDGFO-FWAVGLHBSA-N 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 4
- 208000035143 Bacterial infection Diseases 0.000 abstract 2
- 206010037075 Protozoal infections Diseases 0.000 abstract 2
- 230000001580 bacterial effect Effects 0.000 abstract 2
- 208000022362 bacterial infectious disease Diseases 0.000 abstract 2
- 239000003242 anti bacterial agent Substances 0.000 abstract 1
- 230000000844 anti-bacterial effect Effects 0.000 abstract 1
- 239000003904 antiprotozoal agent Substances 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 208000035475 disorder Diseases 0.000 abstract 1
- 208000015181 infectious disease Diseases 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 239000000651 prodrug Substances 0.000 abstract 1
- 229940002612 prodrug Drugs 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 239000012453 solvate Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/203—Monocyclic carbocyclic rings other than cyclohexane rings; Bicyclic carbocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/44—Preparation of O-glycosides, e.g. glucosides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- General Chemical & Material Sciences (AREA)
- Biotechnology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biochemistry (AREA)
- Veterinary Medicine (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Molecular Biology (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Communicable Diseases (AREA)
- Microbiology (AREA)
- Oncology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Tropical Medicine & Parasitology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
Bulus, formül (1)'e ait bilesiklerle ve bunlarin farmasötik açidan kabul gören tuzlari, ön ilaçlari ve solvatlariyla ilgilidir; buradaki R1 ve R2, burada tanimlandigi gibidir. Formül (1)'e ait bilesikler, çesitli bakteriyel ve protozoal enfeksiyonlarin ve bu enfeksiyonlara bagli bozukluklarin tedavi edilmesi için kullanilabilen antibakteriyel ve antiprotozoal maddelerdir. Bulus, formül (1)'e ait bilesikleri ihtiva eden farmasötik kompozisyonlarla ve bakteriyel ve protozoal enfeksiyonlarin, formül (1)'e ait bilesiklerin uygulanmasi suretiyle tedavi edildigi metotlarla da ilgilidir.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US8404298P | 1998-05-04 | 1998-05-04 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TR200003250T2 true TR200003250T2 (tr) | 2001-01-22 |
Family
ID=22182520
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TR2000/03250T TR200003250T2 (tr) | 1998-05-04 | 1999-05-03 | Higromisin A türevleri |
Country Status (37)
| Country | Link |
|---|---|
| US (1) | US6313100B1 (tr) |
| EP (1) | EP1075483B1 (tr) |
| JP (1) | JP2002513796A (tr) |
| KR (1) | KR100402560B1 (tr) |
| CN (1) | CN1299365A (tr) |
| AP (3) | AP0102296A0 (tr) |
| AR (1) | AR016251A1 (tr) |
| AT (2) | ATE255588T1 (tr) |
| AU (1) | AU755806B2 (tr) |
| BG (1) | BG105008A (tr) |
| BR (1) | BR9910206A (tr) |
| CA (1) | CA2331297C (tr) |
| DE (2) | DE69913333T2 (tr) |
| DK (1) | DK1075483T3 (tr) |
| DZ (1) | DZ2780A1 (tr) |
| EA (2) | EA200200779A1 (tr) |
| ES (1) | ES2209419T3 (tr) |
| GT (1) | GT199900064A (tr) |
| HR (1) | HRP20000747A2 (tr) |
| HU (1) | HUP0102066A3 (tr) |
| ID (1) | ID27030A (tr) |
| IL (1) | IL139165A0 (tr) |
| IS (1) | IS5681A (tr) |
| MA (1) | MA24852A1 (tr) |
| NO (1) | NO20005552L (tr) |
| NZ (1) | NZ507452A (tr) |
| OA (1) | OA11508A (tr) |
| PA (1) | PA8471801A1 (tr) |
| PE (1) | PE20000478A1 (tr) |
| PL (1) | PL344521A1 (tr) |
| PT (1) | PT1075483E (tr) |
| SK (1) | SK16452000A3 (tr) |
| TN (1) | TNSN99083A1 (tr) |
| TR (1) | TR200003250T2 (tr) |
| WO (1) | WO1999057125A2 (tr) |
| YU (1) | YU66900A (tr) |
| ZA (1) | ZA993064B (tr) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NZ511424A (en) * | 1998-12-02 | 2003-08-29 | Pfizer Prod Inc | Hygromycin A derivatives as antibacterial agents |
| GB9923078D0 (en) * | 1999-09-29 | 1999-12-01 | Phytopharm Plc | Sapogenin derivatives and their use |
| US6771019B1 (en) * | 1999-05-14 | 2004-08-03 | Ifire Technology, Inc. | Electroluminescent laminate with patterned phosphor structure and thick film dielectric with improved dielectric properties |
| CZ20023859A3 (cs) * | 2000-06-02 | 2004-02-18 | Pfizer Products Inc. | Deriváty hygromycinu A pro léčení bakteriálních a protozoálních infekcí |
| CN102168034B (zh) * | 2010-11-29 | 2012-12-05 | 中国科学院南海海洋研究所 | 一种海洋链霉菌以及利用该菌制备替达霉素a和b的方法 |
| JP2016069333A (ja) * | 2014-09-30 | 2016-05-09 | 公益財団法人微生物化学研究会 | 新規化合物、その製造方法、及びその用途、並びに、新規微生物 |
| CN104480039B (zh) * | 2014-11-25 | 2017-09-12 | 辽宁大学 | 抗生素产生菌及其应用 |
| US12233081B2 (en) | 2018-08-20 | 2025-02-25 | Northeastern University | Hygromycin a compounds and methods of treating spirochete diseases |
| KR102756165B1 (ko) * | 2019-07-16 | 2025-01-20 | 재단법인 한국파스퇴르연구소 | 항―메티실린 내성 황색포도상구균 화합물 및 이의 의약 용도 |
| TWI771766B (zh) | 2019-10-04 | 2022-07-21 | 美商輝瑞股份有限公司 | 二醯基甘油醯基轉移酶2 抑制劑 |
| JP2022058085A (ja) | 2020-02-24 | 2022-04-11 | ファイザー・インク | ジアシルグリセロールアシルトランスフェラーゼ2阻害剤とアセチル-CoAカルボキシラーゼ阻害剤との組合せ |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0213692B1 (en) * | 1985-06-27 | 1990-09-26 | Takeda Chemical Industries, Ltd. | Use of hygromycin and epihygromycin in the treatment of swine dysentery |
| GB8605245D0 (en) * | 1986-03-04 | 1986-04-09 | Fujisawa Pharmaceutical Co | Prophylactic & therapeutic agent |
-
1999
- 1999-05-03 TR TR2000/03250T patent/TR200003250T2/tr unknown
- 1999-05-03 IL IL13916599A patent/IL139165A0/xx unknown
- 1999-05-03 SK SK1645-2000A patent/SK16452000A3/sk unknown
- 1999-05-03 DK DK99914722T patent/DK1075483T3/da active
- 1999-05-03 AT AT99914722T patent/ATE255588T1/de not_active IP Right Cessation
- 1999-05-03 DE DE69913333T patent/DE69913333T2/de not_active Expired - Fee Related
- 1999-05-03 ES ES99914722T patent/ES2209419T3/es not_active Expired - Lifetime
- 1999-05-03 AU AU33419/99A patent/AU755806B2/en not_active Ceased
- 1999-05-03 HU HU0102066A patent/HUP0102066A3/hu unknown
- 1999-05-03 KR KR10-2000-7012266A patent/KR100402560B1/ko not_active Expired - Fee Related
- 1999-05-03 DZ DZ990080A patent/DZ2780A1/xx active
- 1999-05-03 CA CA002331297A patent/CA2331297C/en not_active Expired - Fee Related
- 1999-05-03 PL PL99344521A patent/PL344521A1/xx not_active Application Discontinuation
- 1999-05-03 HR HR20000747A patent/HRP20000747A2/hr not_active Application Discontinuation
- 1999-05-03 CN CN99805807A patent/CN1299365A/zh active Pending
- 1999-05-03 BR BR9910206-4A patent/BR9910206A/pt not_active IP Right Cessation
- 1999-05-03 ID IDW20002255A patent/ID27030A/id unknown
- 1999-05-03 GT GT199900064A patent/GT199900064A/es unknown
- 1999-05-03 JP JP2000547094A patent/JP2002513796A/ja active Pending
- 1999-05-03 EA EA200200779A patent/EA200200779A1/ru unknown
- 1999-05-03 MA MA25565A patent/MA24852A1/fr unknown
- 1999-05-03 AR ARP990102059A patent/AR016251A1/es not_active Application Discontinuation
- 1999-05-03 US US09/462,592 patent/US6313100B1/en not_active Expired - Fee Related
- 1999-05-03 PE PE1999000362A patent/PE20000478A1/es not_active Application Discontinuation
- 1999-05-03 NZ NZ507452A patent/NZ507452A/xx unknown
- 1999-05-03 PT PT99914722T patent/PT1075483E/pt unknown
- 1999-05-03 WO PCT/IB1999/000795 patent/WO1999057125A2/en not_active Ceased
- 1999-05-03 EP EP99914722A patent/EP1075483B1/en not_active Expired - Lifetime
- 1999-05-03 TN TNTNSN99083A patent/TNSN99083A1/fr unknown
- 1999-05-03 ZA ZA9903064A patent/ZA993064B/xx unknown
- 1999-05-03 DE DE69929723T patent/DE69929723D1/de not_active Expired - Lifetime
- 1999-05-03 YU YU66900A patent/YU66900A/sh unknown
- 1999-05-03 AP APAP/P/2001/002296A patent/AP0102296A0/en unknown
- 1999-05-03 AT AT03020745T patent/ATE317448T1/de not_active IP Right Cessation
- 1999-05-03 EA EA200001029A patent/EA003305B1/ru not_active IP Right Cessation
- 1999-05-04 AP APAP/P/1999/001527A patent/AP1266A/en active
- 1999-05-04 PA PA19998471801A patent/PA8471801A1/es unknown
- 1999-05-04 AP AP2001002296A patent/AP2001002296A0/xx unknown
-
2000
- 2000-10-24 IS IS5681A patent/IS5681A/is unknown
- 2000-10-27 OA OA1200000299A patent/OA11508A/en unknown
- 2000-11-03 NO NO20005552A patent/NO20005552L/no not_active Application Discontinuation
- 2000-11-30 BG BG105008A patent/BG105008A/xx unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| EA200100623A1 (ru) | Кетолидные антибиотики | |
| GT199900208A (es) | Antibiòticos cetòlidos carbamato y carbazato. | |
| AP2001002131A0 (en) | Novel macrolide antibiotics. | |
| TR200400630T4 (tr) | Ketolit antibiyotikleri | |
| NZ507452A (en) | Hygromycin a derivatives | |
| PT1167376E (pt) | Antibioticos macrolidos | |
| TR200003249T2 (tr) | 2''-Deoksi higromisin türevleri | |
| AP2001002154A0 (en) | Hygromycin a derivatives (changed by the ISA to read hygromycin a derivatives as antibacterial agents. | |
| MXPA02011966A (es) | Derivados de higromicina a para el el tratamiento de infecciones bacterianas y por protozoarios. | |
| TR200201143T2 (tr) | Higromisin a ön-ilaçları. | |
| ECSP992931A (es) | Derivados de 2'' desoxi higromicina | |
| ECSP992943A (es) | Derivados de higromicina a | |
| ECSP993239A (es) | Derivados de higromicina |