TR200003281T2 - CD-23'e karşı antikorlar, bunların türevleri ve terapötik kullanımları. - Google Patents

CD-23'e karşı antikorlar, bunların türevleri ve terapötik kullanımları.

Info

Publication number
TR200003281T2
TR200003281T2 TR2000/03281T TR200003281T TR200003281T2 TR 200003281 T2 TR200003281 T2 TR 200003281T2 TR 2000/03281 T TR2000/03281 T TR 2000/03281T TR 200003281 T TR200003281 T TR 200003281T TR 200003281 T2 TR200003281 T2 TR 200003281T2
Authority
TR
Turkey
Prior art keywords
antibodies
derivatives
therapeutic uses
rii
bind
Prior art date
Application number
TR2000/03281T
Other languages
English (en)
Inventor
Marcel Paul Bonnefoy Jean-Yves
James Crowe Scott
Henry Ellis Jonathan
Timothy Rapson Nicholas
Shearin Jean
Original Assignee
Glaxo Group Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Limited filed Critical Glaxo Group Limited
Publication of TR200003281T2 publication Critical patent/TR200003281T2/tr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2851—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the lectin superfamily, e.g. CD23, CD72
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Bulus, CD23 (FC RII) tip II molekülüne baglanan antikorlara, özellikle, 1x10 Ka Mo1 den daha büyük ya da esit bir afinite sabiti ile vasiflanan CD23 (FC RII) tip II molekülüne baglanan antikorlari kapsayan degistirilmis antikorlara, bu antikorlarin hazirlanmasi, bu antikorlari ihtiva eden farmasötik bilesimler ve bunlarin terapide, özellikle otoimün ve iltihapli bozukluklarin tedavisinde kullanimlarina iliskindir.
TR2000/03281T 1998-05-09 1999-05-07 CD-23'e karşı antikorlar, bunların türevleri ve terapötik kullanımları. TR200003281T2 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9809839.5A GB9809839D0 (en) 1998-05-09 1998-05-09 Antibody

Publications (1)

Publication Number Publication Date
TR200003281T2 true TR200003281T2 (tr) 2001-03-21

Family

ID=10831668

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2000/03281T TR200003281T2 (tr) 1998-05-09 1999-05-07 CD-23'e karşı antikorlar, bunların türevleri ve terapötik kullanımları.

Country Status (25)

Country Link
US (1) US7008623B1 (tr)
EP (1) EP1076701A1 (tr)
JP (1) JP2002514421A (tr)
KR (1) KR20010043470A (tr)
CN (1) CN1308676A (tr)
AP (1) AP1547A (tr)
AU (1) AU763491B2 (tr)
BR (1) BR9910327A (tr)
CA (1) CA2328606A1 (tr)
EA (1) EA200001041A1 (tr)
EE (1) EE200000658A (tr)
GB (1) GB9809839D0 (tr)
HR (1) HRP20000762A2 (tr)
HU (1) HUP0102005A3 (tr)
ID (1) ID28088A (tr)
IL (1) IL139384A0 (tr)
IS (1) IS5696A (tr)
NO (1) NO20005632L (tr)
NZ (1) NZ507879A (tr)
PL (1) PL344019A1 (tr)
SK (1) SK16762000A3 (tr)
TR (1) TR200003281T2 (tr)
WO (1) WO1999058679A1 (tr)
YU (1) YU69000A (tr)
ZA (1) ZA200006312B (tr)

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US20060246075A1 (en) * 2004-09-29 2006-11-02 Marc Mercken Anti-amyloid antibodies, compositions, methods and uses
WO2006074399A2 (en) 2005-01-05 2006-07-13 Biogen Idec Ma Inc. Multispecific binding molecules comprising connecting peptides
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GB0525662D0 (en) 2005-12-16 2006-01-25 Glaxo Group Ltd Immunoglobulins
EP1804172B1 (en) * 2005-12-20 2021-08-11 Roche Diagnostics GmbH PCR elbow determination using curvature analysis of a double sigmoid
US7680868B2 (en) * 2005-12-20 2010-03-16 Roche Molecular Systems, Inc. PCR elbow determination by use of a double sigmoid function curve fit with the Levenburg-Marquardt algorithm and normalization
WO2009043051A2 (en) * 2007-09-27 2009-04-02 Biogen Idec Ma Inc. Cd23 binding molecules and methods of use thereof
TW200944231A (en) 2007-11-30 2009-11-01 Glaxo Group Ltd Antigen-binding constructs
KR101304150B1 (ko) 2008-03-04 2013-09-05 라브리스 바이올로직스 인코포레이티드 만성 통증의 치료 방법
PE20091964A1 (es) 2008-05-06 2010-01-09 Glaxo Group Ltd Encapsulacion de agentes biologicamente activos
US20110305693A1 (en) 2009-02-24 2011-12-15 Glaxo Group Limited Anitigen-binding constructs
CA2753287A1 (en) 2009-02-24 2010-09-02 Glaxo Group Limited Antigen-binding constructs
EP2401296A1 (en) 2009-02-24 2012-01-04 Glaxo Group Limited Multivalent and/or multispecific rankl-binding constructs
WO2010115786A1 (en) 2009-04-01 2010-10-14 Glaxo Group Limited Anti-il-23 immunoglobulins
EP2421611A1 (en) 2009-04-24 2012-02-29 Glaxo Group Limited Fgfr1c antibody combinations
BR112012004464B8 (pt) 2009-08-28 2021-05-25 Labrys Biologics Inc uso de um anticorpo antagonista anti-cgrp para preparar uma composição farmacêutica para tratar e/ou prevenir dor visceral e/ou um ou mais sintomas de dor visceral, em que a dor visceral está associada á cistite intersticial (ic), e dita composição farmacêutica
FR2957598B1 (fr) * 2010-03-17 2015-12-04 Lfb Biotechnologies Nouveau peptide signal, et son utilisation pour la production de proteines recombinantes
MX351887B (es) 2010-11-23 2017-11-01 Glaxo Group Ltd Proteinas de union a antigeno para oncostatina m (osm).
MX2013005847A (es) 2010-11-24 2013-12-12 Glaxo Group Ltd Proteinas de union a antigeno multiespecificas que eligen como blanco a hgf.
US8974782B2 (en) 2011-02-07 2015-03-10 Glaxo Group Limited Treatment of stroke comprising anti-MAG antibodies
EP2714737A1 (en) 2011-05-27 2014-04-09 Glaxo Group Limited Bcma (cd269/tnfrsf17) -binding proteins
EP2888279A1 (en) 2012-08-22 2015-07-01 Glaxo Group Limited Anti lrp6 antibodies
US10176293B2 (en) 2012-10-02 2019-01-08 Roche Molecular Systems, Inc. Universal method to determine real-time PCR cycle threshold values
RS60538B1 (sr) 2013-03-15 2020-08-31 Glaxosmithkline Ip Dev Ltd Anti-lag-3 vezujući proteini
US9777057B2 (en) * 2013-07-10 2017-10-03 Onconox Aps Antibodies to β2-glycoprotein I and therapeutic uses thereof
US10556945B2 (en) 2014-03-21 2020-02-11 Teva Pharmaceuticals International Gmbh Antagonist antibodies directed against calcitonin gene-related peptide and methods using same
MX378344B (es) 2014-03-21 2025-03-10 Teva Pharmaceuticals Int Gmbh Anticuerpos antagonistas dirigidos contra el peptido relacionado con el gen de calcitonina y metodos que usan los mismos.
RU2760582C2 (ru) 2015-09-02 2021-11-29 Иммутеп С.А.С. Анти-LAG-3 антитела
US10479827B2 (en) 2016-05-31 2019-11-19 Sysmex Corporation Monoclonal antibody reacting with glycopeptide, and use thereof
JP6935184B2 (ja) * 2016-05-31 2021-09-15 シスメックス株式会社 糖ペプチドと反応するモノクローナル抗体およびその用途
KR102379464B1 (ko) 2016-06-20 2022-03-29 키맵 리미티드 항-pd-l1 항체
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IE922437A1 (en) * 1991-07-25 1993-01-27 Idec Pharma Corp Recombinant antibodies for human therapy
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HU223006B1 (hu) * 1994-10-25 2004-03-01 Glaxo Group Ltd. CD23-hoz kötődő vegyületek
US6011138A (en) * 1997-02-20 2000-01-04 Idec Pharmaceuticals Corporation Gamma-1 anti-human CD23 monoclonal antibodies

Also Published As

Publication number Publication date
BR9910327A (pt) 2001-01-30
WO1999058679A1 (en) 1999-11-18
CN1308676A (zh) 2001-08-15
CA2328606A1 (en) 1999-11-18
JP2002514421A (ja) 2002-05-21
PL344019A1 (en) 2001-09-24
HRP20000762A2 (en) 2001-06-30
HUP0102005A3 (en) 2003-10-28
AP2000001983A0 (en) 2000-12-31
EE200000658A (et) 2002-04-15
EA200001041A1 (ru) 2001-06-25
AU763491B2 (en) 2003-07-24
NZ507879A (en) 2004-02-27
IL139384A0 (en) 2001-11-25
GB9809839D0 (en) 1998-07-08
US7008623B1 (en) 2006-03-07
IS5696A (is) 2000-10-31
EP1076701A1 (en) 2001-02-21
NO20005632D0 (no) 2000-11-08
ID28088A (id) 2001-05-03
HUP0102005A2 (hu) 2001-10-28
KR20010043470A (ko) 2001-05-25
YU69000A (sh) 2003-08-29
SK16762000A3 (sk) 2001-07-10
NO20005632L (no) 2001-01-08
AU3836799A (en) 1999-11-29
AP1547A (en) 2006-01-13
ZA200006312B (en) 2003-02-26

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