TR200103703T2 - Anti-alfa,beta3 rekombinant insan antikorları, bunları kodlayan nükleik asitler - Google Patents

Anti-alfa,beta3 rekombinant insan antikorları, bunları kodlayan nükleik asitler

Info

Publication number
TR200103703T2
TR200103703T2 TR2001/03703T TR200103703T TR200103703T2 TR 200103703 T2 TR200103703 T2 TR 200103703T2 TR 2001/03703 T TR2001/03703 T TR 2001/03703T TR 200103703 T TR200103703 T TR 200103703T TR 200103703 T2 TR200103703 T2 TR 200103703T2
Authority
TR
Turkey
Prior art keywords
beta3
alpha
nucleic acids
human antibodies
recombinant human
Prior art date
Application number
TR2001/03703T
Other languages
English (en)
Inventor
D. Huse William
Wu Herren
Original Assignee
Applied Molecular Evolution Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23331188&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=TR200103703(T2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Applied Molecular Evolution Inc. filed Critical Applied Molecular Evolution Inc.
Publication of TR200103703T2 publication Critical patent/TR200103703T2/tr

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2839—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily
    • C07K16/2848—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily against integrin beta3-subunit-containing molecules, e.g. CD41, CD51, CD61
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565—Complementarity determining region [CDR]

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
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  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Dermatology (AREA)
  • Urology & Nephrology (AREA)
  • Neurology (AREA)
  • Pain & Pain Management (AREA)
  • Ophthalmology & Optometry (AREA)
  • Oncology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Bulus alfavbeta3'e karsi seçici baglayici ilgisi sergileyen güçlendirilmis LM609 asilanmis antikorlari yada bunun islevsel bir parçasini saglar. Bulus, güçlendirilmis LM609 asilanmis antikorlari sifreleyen nükleik asit moleküllerini de saglar. Ek olarak alfavbeta3'ün bir fonksiyonunu önleme yöntemleri de saglamaktadir.
TR2001/03703T 1999-06-24 2000-06-23 Anti-alfa,beta3 rekombinant insan antikorları, bunları kodlayan nükleik asitler TR200103703T2 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US09/339,922 US6531580B1 (en) 1999-06-24 1999-06-24 Anti-αvβ3 recombinant human antibodies and nucleic acids encoding same

Publications (1)

Publication Number Publication Date
TR200103703T2 true TR200103703T2 (tr) 2002-04-22

Family

ID=23331188

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2001/03703T TR200103703T2 (tr) 1999-06-24 2000-06-23 Anti-alfa,beta3 rekombinant insan antikorları, bunları kodlayan nükleik asitler

Country Status (19)

Country Link
US (3) US6531580B1 (tr)
EP (1) EP1189946A1 (tr)
JP (2) JP4521802B2 (tr)
KR (1) KR100928748B1 (tr)
AU (3) AU781501C (tr)
BR (1) BR0011849A (tr)
CA (1) CA2375236A1 (tr)
CR (1) CR6538A (tr)
CZ (1) CZ302177B6 (tr)
HU (1) HUP0201783A3 (tr)
IL (2) IL147145A0 (tr)
MX (1) MXPA01013362A (tr)
NO (1) NO20016243L (tr)
NZ (3) NZ523291A (tr)
PL (1) PL352251A1 (tr)
SK (1) SK19072001A3 (tr)
TR (1) TR200103703T2 (tr)
WO (1) WO2000078815A1 (tr)
ZA (1) ZA200110161B (tr)

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HUP0201783A2 (en) 2002-08-28
AU2005204251A1 (en) 2005-09-22
HUP0201783A3 (en) 2011-03-28
CA2375236A1 (en) 2000-12-28
BR0011849A (pt) 2003-05-27
KR100928748B1 (ko) 2009-11-25
CZ20014655A3 (cs) 2002-05-15
JP2009219495A (ja) 2009-10-01
NO20016243D0 (no) 2001-12-19
PL352251A1 (en) 2003-08-11
WO2000078815A1 (en) 2000-12-28
US7667007B2 (en) 2010-02-23
US6531580B1 (en) 2003-03-11
AU2008261144A1 (en) 2009-01-22
US20030166872A1 (en) 2003-09-04
ZA200110161B (en) 2002-09-30
AU781501B2 (en) 2005-05-26
AU2005204251B2 (en) 2008-10-02
JP2004537957A (ja) 2004-12-24
JP4521802B2 (ja) 2010-08-11
NO20016243L (no) 2002-02-15
AU781501C (en) 2006-04-06
NZ523291A (en) 2004-09-24
AU2005204251A9 (en) 2005-09-22
CR6538A (es) 2006-02-06
KR20020034094A (ko) 2002-05-08
US7371382B2 (en) 2008-05-13
CZ302177B6 (cs) 2010-12-01
US20090023900A1 (en) 2009-01-22
NZ516251A (en) 2003-03-28
SK19072001A3 (sk) 2002-07-02
MXPA01013362A (es) 2003-09-04
AU5637400A (en) 2001-01-09
IL195649A0 (en) 2009-09-01
EP1189946A1 (en) 2002-03-27
NZ533727A (en) 2008-03-28
IL147145A0 (en) 2002-08-14

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