TR200200461T2 - Alfa-Lipoik asit veya türevlerinin uygulanmasıyla migren tedavisi - Google Patents
Alfa-Lipoik asit veya türevlerinin uygulanmasıyla migren tedavisiInfo
- Publication number
- TR200200461T2 TR200200461T2 TR2002/00461T TR200200461T TR200200461T2 TR 200200461 T2 TR200200461 T2 TR 200200461T2 TR 2002/00461 T TR2002/00461 T TR 2002/00461T TR 200200461 T TR200200461 T TR 200200461T TR 200200461 T2 TR200200461 T2 TR 200200461T2
- Authority
- TR
- Turkey
- Prior art keywords
- lipoic acid
- alpha
- derivatives
- application
- migraine treatment
- Prior art date
Links
- AGBQKNBQESQNJD-UHFFFAOYSA-N lipoic acid Chemical compound OC(=O)CCCCC1CCSS1 AGBQKNBQESQNJD-UHFFFAOYSA-N 0.000 title abstract 4
- 208000019695 Migraine disease Diseases 0.000 title abstract 2
- 235000019136 lipoic acid Nutrition 0.000 title abstract 2
- 206010027599 migraine Diseases 0.000 title abstract 2
- 229960002663 thioctic acid Drugs 0.000 title abstract 2
- HBAQYPYDRFILMT-UHFFFAOYSA-N 8-[3-(1-cyclopropylpyrazol-4-yl)-1H-pyrazolo[4,3-d]pyrimidin-5-yl]-3-methyl-3,8-diazabicyclo[3.2.1]octan-2-one Chemical class C1(CC1)N1N=CC(=C1)C1=NNC2=C1N=C(N=C2)N1C2C(N(CC1CC2)C)=O HBAQYPYDRFILMT-UHFFFAOYSA-N 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 150000001408 amides Chemical class 0.000 abstract 1
- 230000001684 chronic effect Effects 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 150000007970 thio esters Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
- A61K31/405—Indole-alkanecarboxylic acids; Derivatives thereof, e.g. tryptophan, indomethacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/38—Heterocyclic compounds having sulfur as a ring hetero atom
- A61K31/385—Heterocyclic compounds having sulfur as a ring hetero atom having two or more sulfur atoms in the same ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/48—Ergoline derivatives, e.g. lysergic acid, ergotamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/06—Free radical scavengers or antioxidants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Pain & Pain Management (AREA)
- Diabetes (AREA)
- Nutrition Science (AREA)
- Toxicology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Hospice & Palliative Care (AREA)
- Otolaryngology (AREA)
- Biochemistry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Bulus, migrenin önlenmesinde ya da migrenin akut ya da kronik tedavisinde aktif içerik olarak, azaltilmis ya da oksitlenmis formda, rasemik alfa-lipoik asit ya da onun enantiomerlerinin ya da farmasötik olarak kabul edilebilir tuzlari, amidleri, esterleri ya da tiyoesterlerinin kullanimi ile ilgilidir.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19941217A DE19941217A1 (de) | 1999-08-30 | 1999-08-30 | Behandlung der Migräne durch Verabreichung von alpha-Liponsäure oder Derivaten derselben |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TR200200461T2 true TR200200461T2 (tr) | 2002-08-21 |
Family
ID=7920152
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TR2002/00461T TR200200461T2 (tr) | 1999-08-30 | 2000-08-26 | Alfa-Lipoik asit veya türevlerinin uygulanmasıyla migren tedavisi |
Country Status (31)
| Country | Link |
|---|---|
| US (1) | US6251935B1 (tr) |
| EP (1) | EP1207878B1 (tr) |
| JP (1) | JP4773015B2 (tr) |
| KR (1) | KR100624215B1 (tr) |
| CN (1) | CN1170535C (tr) |
| AT (1) | ATE232725T1 (tr) |
| AU (1) | AU781505B2 (tr) |
| BG (1) | BG65735B1 (tr) |
| BR (1) | BR0013651A (tr) |
| CA (1) | CA2382548C (tr) |
| CZ (1) | CZ301789B6 (tr) |
| DE (2) | DE19941217A1 (tr) |
| DK (1) | DK1207878T3 (tr) |
| EE (1) | EE04869B1 (tr) |
| ES (1) | ES2190985T3 (tr) |
| HR (1) | HRP20020168A2 (tr) |
| HU (1) | HU229603B1 (tr) |
| IL (2) | IL148068A0 (tr) |
| IS (1) | IS2214B (tr) |
| MX (1) | MXPA02002246A (tr) |
| NO (1) | NO328692B1 (tr) |
| NZ (1) | NZ517276A (tr) |
| PL (1) | PL200928B1 (tr) |
| PT (1) | PT1207878E (tr) |
| RS (1) | RS50139B (tr) |
| RU (1) | RU2232577C2 (tr) |
| SK (1) | SK286260B6 (tr) |
| TR (1) | TR200200461T2 (tr) |
| UA (1) | UA71031C2 (tr) |
| WO (1) | WO2001015693A2 (tr) |
| ZA (1) | ZA200201637B (tr) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6900338B1 (en) * | 1998-11-25 | 2005-05-31 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Scavenger compounds |
| US7030154B2 (en) | 2002-06-07 | 2006-04-18 | Juvenon, Inc. | Stability of lipoic acid |
| US20050065094A1 (en) | 2003-09-05 | 2005-03-24 | Boehringer Ingelheim International Gmbh | Use of telmisartan for the prevention and treatment of vascular headache |
| US20050282879A1 (en) * | 2004-06-17 | 2005-12-22 | Foad Salehani | Methods and composition for treatment of migraine and symptoms thereof |
| US20090054513A1 (en) * | 2007-08-22 | 2009-02-26 | Response Scientific, Inc. | Method of managing blood glucose levels, insulin levels and/or insulin receptor functionality in individuals with diabetes, polycystic ovarian syndrome and/or alzheimer's disease |
| US7943163B2 (en) | 2007-08-22 | 2011-05-17 | Response Scientific, Inc. | Medical food or nutritional supplement, method of manufacturing same, and method of managing diabetes |
| RU2424803C2 (ru) * | 2008-04-07 | 2011-07-27 | Учреждение Российской академии медицинских наук Научно-исследовательский институт фармакологии имени В.В. Закусова РАМН (НИИ фармакологии имени В.В.Закусова РАМН) | Фармацевтическая композиция с противомигреневым действием (варианты) |
| WO2010060098A1 (en) | 2008-11-24 | 2010-05-27 | Cedars-Sinai Medical Center | Antioxidant camptothecin derivatives and antioxidant antineoplastic nanospheres thereof |
| CA2762022A1 (en) | 2009-05-15 | 2010-11-18 | Redx Pharma Limited | Redox drug derivatives |
| KR100935554B1 (ko) | 2009-06-24 | 2010-01-07 | 주식회사 셀트리온제약 | 피페라진 다이티옥트산염 및 이를 포함하는 약제학적 조성물 |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SU620265A1 (ru) * | 1977-02-21 | 1978-08-25 | Центральный Ордена Трудового Красного Знамени Научно-Исследовательский Институт Курортологии И Физиотерапии | Способ лечени атеросклероза сосудов головного мозга и гипертонической болезни |
| DE58902094D1 (de) * | 1988-01-28 | 1992-10-01 | Koeltringer Peter | Kombinationspraeparat zur behandlung von nervenzell-und nervenfasererkrankungen und verletzungen. |
| FI895821A7 (fi) * | 1988-12-07 | 1990-06-08 | The Wellcome Foundation Ltd | Farmaseuttisesti aktivisia CNS-yhdisteitä |
| ES2115589T3 (es) * | 1989-11-09 | 1998-07-01 | Asta Medica Ag | Medicamento que contiene acido r-alfa-liponico o acido s-alfa-liponico como sustancia activa. |
| US5569670A (en) * | 1992-06-05 | 1996-10-29 | Asta Medica Aktiengesellschaft | Combination medications containing alpha-lipoic acid and related |
| DE4218572A1 (de) * | 1992-06-05 | 1993-12-09 | Asta Medica Ag | Synergistische Kombination von Arzneimitteln enthaltend als Wirkstoff alpha-Liponsäure, Dihydroliponsäure, deren Metaboliten sowie die oxidierten und reduzierten Enantiomere der alpha-Liponsäure wie die R-alpha-Liponsäure oder S-alpha-Liponsäure sowie Metaboliten der alpha-Liponsäure mit den Vitaminen A, B1-6, B12, C und E |
| DE69331727D1 (de) * | 1992-06-30 | 2002-04-25 | Howard K Shapiro | Verwendung einer kombination bestehend aus einem aminderivat oder aminverwandten derivat der benzoesäure und einem amino-polysaccharide zur herstellung eines medikaments fuer die behandlung von entzündlichen erkrankungen |
| DE4327426A1 (de) * | 1993-08-14 | 1995-02-16 | F H Erdaussiebung Gmbh | Anbaugerät zum Sieben und Verfüllen von Erdmaterialien |
| DE4327462A1 (de) * | 1993-08-16 | 1995-02-23 | Carl Heinrich Dr Weischer | Neue N-Acetyl-p-Aminophenol-Derivate zur Bekämpfung von Schmerzzuständen |
| DE4331168A1 (de) * | 1993-09-14 | 1995-03-16 | Carl Heinrich Dr Weischer | Kombination von N-Acetyl-p-Aminophenol mit schwefelenthaltenden Carbonsäuren, wie z. B. alpha-Liponsäure und deren Derivate, zur Bekämpfung von Schmerzzuständen |
| EP0855396A1 (en) * | 1997-01-22 | 1998-07-29 | ASTA Medica Aktiengesellschaft | Thioctic acid metabolites and methods of use thereof |
| IL123887A0 (en) * | 1997-04-02 | 1998-10-30 | Sankyo Co | Dithiolan derivatives their use and pharmaceutical compositions containing the same |
| WO1999006040A1 (en) * | 1997-08-04 | 1999-02-11 | Berry Christopher J | Method of treating disease using a tocotrienol and alpha-lipoic acid or derivatives or an ester thereof |
| GB2333757B (en) * | 1998-02-03 | 2001-06-27 | Cheung Kwok Chung | Sliding platform |
| EP1065931A4 (en) * | 1998-04-02 | 2006-10-11 | Avicena Group Inc | COMPOSITIONS CONTAINING CREATINE COMBINED WITH A SECOND AGENT |
| AR042572A1 (es) * | 1999-04-02 | 2005-06-29 | Sod Conseils Rech Applic | Derivados de acido lipoico, procedimiento para su preparacion, medicamentos y composiciones farmaceuticas que los contienen y utilizacion de dichos derivados para la preparacion de los referidos medicamentos |
-
1999
- 1999-08-30 DE DE19941217A patent/DE19941217A1/de not_active Ceased
-
2000
- 2000-08-15 US US09/638,034 patent/US6251935B1/en not_active Expired - Lifetime
- 2000-08-26 AT AT00960527T patent/ATE232725T1/de active
- 2000-08-26 IL IL14806800A patent/IL148068A0/xx active IP Right Grant
- 2000-08-26 PT PT00960527T patent/PT1207878E/pt unknown
- 2000-08-26 PL PL352741A patent/PL200928B1/pl unknown
- 2000-08-26 HU HU0203025A patent/HU229603B1/hu not_active IP Right Cessation
- 2000-08-26 RS YUP-150/02A patent/RS50139B/sr unknown
- 2000-08-26 AU AU72799/00A patent/AU781505B2/en not_active Ceased
- 2000-08-26 HR HR20020168A patent/HRP20020168A2/hr not_active Application Discontinuation
- 2000-08-26 JP JP2001519907A patent/JP4773015B2/ja not_active Expired - Fee Related
- 2000-08-26 SK SK290-2002A patent/SK286260B6/sk not_active IP Right Cessation
- 2000-08-26 CZ CZ20020655A patent/CZ301789B6/cs not_active IP Right Cessation
- 2000-08-26 ES ES00960527T patent/ES2190985T3/es not_active Expired - Lifetime
- 2000-08-26 NZ NZ517276A patent/NZ517276A/en not_active IP Right Cessation
- 2000-08-26 KR KR1020027002638A patent/KR100624215B1/ko not_active Expired - Fee Related
- 2000-08-26 RU RU2002106751/14A patent/RU2232577C2/ru active
- 2000-08-26 EE EEP200200098A patent/EE04869B1/xx not_active IP Right Cessation
- 2000-08-26 DE DE50001301T patent/DE50001301D1/de not_active Expired - Lifetime
- 2000-08-26 CN CNB008122032A patent/CN1170535C/zh not_active Expired - Fee Related
- 2000-08-26 UA UA2002032400A patent/UA71031C2/uk unknown
- 2000-08-26 WO PCT/EP2000/008315 patent/WO2001015693A2/de not_active Ceased
- 2000-08-26 TR TR2002/00461T patent/TR200200461T2/tr unknown
- 2000-08-26 DK DK00960527T patent/DK1207878T3/da active
- 2000-08-26 BR BR0013651-4A patent/BR0013651A/pt not_active Application Discontinuation
- 2000-08-26 CA CA002382548A patent/CA2382548C/en not_active Expired - Fee Related
- 2000-08-26 EP EP00960527A patent/EP1207878B1/de not_active Expired - Lifetime
- 2000-08-26 MX MXPA02002246A patent/MXPA02002246A/es active IP Right Grant
-
2002
- 2002-02-06 IL IL148068A patent/IL148068A/en not_active IP Right Cessation
- 2002-02-12 BG BG106407A patent/BG65735B1/bg unknown
- 2002-02-25 NO NO20020917A patent/NO328692B1/no not_active IP Right Cessation
- 2002-02-26 IS IS6284A patent/IS2214B/is unknown
- 2002-02-27 ZA ZA200201637A patent/ZA200201637B/en unknown
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