TR200403020T2 - (S)-4-Amino-5-kloro-2-metoksi-N- (1-(1-(2-tetrahidrofuril-carbonil)-4-piperidinylmetil) -4-piperidinil)benzamit, bunun hazırlama işlemi ve aynı formülü ve bunun ara mamülünü içeren farmasötik bileşim - Google Patents

(S)-4-Amino-5-kloro-2-metoksi-N- (1-(1-(2-tetrahidrofuril-carbonil)-4-piperidinylmetil) -4-piperidinil)benzamit, bunun hazırlama işlemi ve aynı formülü ve bunun ara mamülünü içeren farmasötik bileşim

Info

Publication number
TR200403020T2
TR200403020T2 TR2004/03020T TR200403020T TR200403020T2 TR 200403020 T2 TR200403020 T2 TR 200403020T2 TR 2004/03020 T TR2004/03020 T TR 2004/03020T TR 200403020 T TR200403020 T TR 200403020T TR 200403020 T2 TR200403020 T2 TR 200403020T2
Authority
TR
Turkey
Prior art keywords
tetrahydrofurylcarbonyl
piperidinylmethyl
benzamide
piperidinyl
chloro
Prior art date
Application number
TR2004/03020T
Other languages
English (en)
Inventor
Kato Shiro
Yamazaki Hiroshi
Hirokawa Yoshimi
Yoshida Naoyuki
Morikage Yukiko
Morikage Kazuo
Kan Yoko
Original Assignee
Dainippon Pharmaceutical Co., Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dainippon Pharmaceutical Co., Ltd. filed Critical Dainippon Pharmaceutical Co., Ltd.
Publication of TR200403020T2 publication Critical patent/TR200403020T2/tr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Mevcut bulus, serotonin 4 reseptöründe ( bu asamadan sonra arada sirada 5-HT4 reseptörü olarak adlandirilacaktir) agonistic faaliyetlere bagli etkileri artiran etkili gastrointestinal hareketlilik gösteren ve kalbe bazi etkileri bulunan yeni (S)-4-amino-5-kloro-2-methoksi-N- [ l - [ l - (2 -tetrahidrofurilkarbonil) -4-piperidinilmetil] -4-piperidinil] benzamit ile ilgilidir.
TR2004/03020T 2002-05-16 2003-05-15 (S)-4-Amino-5-kloro-2-metoksi-N- (1-(1-(2-tetrahidrofuril-carbonil)-4-piperidinylmetil) -4-piperidinil)benzamit, bunun hazırlama işlemi ve aynı formülü ve bunun ara mamülünü içeren farmasötik bileşim TR200403020T2 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2002141262 2002-05-16

Publications (1)

Publication Number Publication Date
TR200403020T2 true TR200403020T2 (tr) 2005-05-23

Family

ID=29267809

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2004/03020T TR200403020T2 (tr) 2002-05-16 2003-05-15 (S)-4-Amino-5-kloro-2-metoksi-N- (1-(1-(2-tetrahidrofuril-carbonil)-4-piperidinylmetil) -4-piperidinil)benzamit, bunun hazırlama işlemi ve aynı formülü ve bunun ara mamülünü içeren farmasötik bileşim

Country Status (26)

Country Link
US (1) US6696468B2 (tr)
EP (1) EP1362857B1 (tr)
JP (1) JP3643107B2 (tr)
KR (1) KR20040107520A (tr)
CN (1) CN1653063A (tr)
AR (1) AR040021A1 (tr)
AT (1) ATE273304T1 (tr)
AU (1) AU2003230245A1 (tr)
BR (1) BR0309933A (tr)
CA (1) CA2483368A1 (tr)
CZ (1) CZ20041084A3 (tr)
DE (1) DE60300021T2 (tr)
DK (1) DK1362857T3 (tr)
ES (1) ES2227500T3 (tr)
HU (1) HUP0501016A2 (tr)
IL (1) IL165012A0 (tr)
MX (1) MXPA04011332A (tr)
NO (1) NO20045469L (tr)
PL (1) PL372724A1 (tr)
PT (1) PT1362857E (tr)
RU (1) RU2004136853A (tr)
SK (1) SK50192004A3 (tr)
TR (1) TR200403020T2 (tr)
TW (1) TW200400186A (tr)
WO (1) WO2003097638A1 (tr)
ZA (1) ZA200409053B (tr)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9904377D0 (sv) * 1999-12-01 1999-12-01 Astra Pharma Prod Pharmaceutical combinations
SE0200844D0 (sv) 2002-03-19 2002-03-19 Astrazeneca Ab Chemical compounds
SE0200843D0 (sv) 2002-03-19 2002-03-19 Astrazeneca Ab Chemical compounds
SE0300957D0 (sv) 2003-04-01 2003-04-01 Astrazeneca Ab Chemical compounds
TW200533348A (en) * 2004-02-18 2005-10-16 Theravance Inc Indazole-carboxamide compounds as 5-ht4 receptor agonists
US8309575B2 (en) 2004-04-07 2012-11-13 Theravance, Inc. Quinolinone-carboxamide compounds as 5-HT4 receptor agonists
US7728006B2 (en) * 2004-04-07 2010-06-01 Theravance, Inc. Quinolinone-carboxamide compounds as 5-HT4 receptor agonists
TWI351282B (en) 2004-04-07 2011-11-01 Theravance Inc Quinolinone-carboxamide compounds as 5-ht4 recepto
JP5042028B2 (ja) * 2004-11-05 2012-10-03 セラヴァンス， インコーポレーテッド キノリノン−カルボキサミド化合物
DE602005016446D1 (de) * 2004-11-05 2009-10-15 Theravance Inc 5-HT4-Rezeptoragonistenverbindungen
KR20070091665A (ko) * 2004-12-22 2007-09-11 세라밴스 인코포레이티드 인다졸－카르복사미드 화합물
WO2006094063A1 (en) * 2005-03-02 2006-09-08 Theravance, Inc. Quinolinone compounds as 5-ht4 receptor agonists
MY147756A (en) 2005-05-25 2013-01-15 Theravance Inc Benzimidazole-carboxamide compounds as 5-ht4 receptor agonists
US7256294B2 (en) * 2005-05-25 2007-08-14 Theravance, Inc. Crystalline form of a benzimidazole-carboxamide medicinal compound
TW200722419A (en) * 2005-05-27 2007-06-16 Astrazeneca Ab Chemical compounds
WO2006126948A1 (en) * 2005-05-27 2006-11-30 Astrazeneca Ab Piperidines for the treatment of chemokine mediated diseases
BRPI0613563A2 (pt) 2005-07-21 2012-01-17 Astrazeneca Ab novos derivados de piperidina
GB0525068D0 (en) 2005-12-08 2006-01-18 Novartis Ag Organic compounds
TWI423967B (zh) * 2008-02-21 2014-01-21 Dainippon Sumitomo Pharma Co 醯胺衍生物及含有其之醫藥組合物
US8349852B2 (en) 2009-01-13 2013-01-08 Novartis Ag Quinazolinone derivatives useful as vanilloid antagonists
AR080055A1 (es) 2010-02-01 2012-03-07 Novartis Ag Derivados de pirazolo-[5,1-b]-oxazol como antagonistas de los receptores de crf -1
WO2011092293A2 (en) 2010-02-01 2011-08-04 Novartis Ag Cyclohexyl amide derivatives as crf receptor antagonists
ES2527849T3 (es) 2010-02-02 2015-01-30 Novartis Ag Derivados de ciclohexilamida como antagonistas del receptor de CRF
AR086554A1 (es) 2011-05-27 2014-01-08 Novartis Ag Derivados de la piperidina 3-espirociclica como agonistas de receptores de la ghrelina
JP2015525202A (ja) 2012-05-03 2015-09-03 ノバルティス アーゲー グレリン受容体アゴニストとしての２，７−ジアザ−スピロ［４，５］デカ−７−イル誘導体のｌ−リンゴ酸塩およびその結晶形態
CN115515933A (zh) * 2020-05-04 2022-12-23 武田药品工业株式会社 经管腔作用的n-(哌啶-4-基)苯甲酰胺衍生物

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH111472A (ja) 1996-04-30 1999-01-06 Dainippon Pharmaceut Co Ltd ベンズアミド誘導体及びそれを含有する医薬組成物
US6294555B1 (en) 1998-04-28 2001-09-25 Dainippon Pharmaceutical Co., Ltd. 1-[(1-Substituted-4-piperidinyl)methyl]-4-piperidine derivative, process for producing the same, medicinal compositions containing the same and intermediates of these compounds
JP2000080081A (ja) 1998-06-24 2000-03-21 Dainippon Pharmaceut Co Ltd １―〔（１―置換―４―ピペリジニル）メチル〕―４―ピペリジン誘導体及びそれを含有する医薬組成物
JP2001122784A (ja) 1999-10-27 2001-05-08 Dainippon Pharmaceut Co Ltd １−［（１−置換−４−ピペリジニル）メチル］−４−ピペリジン誘導体からなる医薬

Also Published As

Publication number Publication date
ATE273304T1 (de) 2004-08-15
HK1060118A1 (en) 2004-07-30
JP2004043453A (ja) 2004-02-12
ZA200409053B (en) 2005-07-12
WO2003097638A1 (en) 2003-11-27
JP3643107B2 (ja) 2005-04-27
AR040021A1 (es) 2005-03-09
TW200400186A (en) 2004-01-01
US20030216433A1 (en) 2003-11-20
MXPA04011332A (es) 2005-02-14
CA2483368A1 (en) 2003-11-27
BR0309933A (pt) 2005-02-09
PT1362857E (pt) 2004-11-30
HUP0501016A2 (en) 2006-02-28
NO20045469L (no) 2005-02-16
SK50192004A3 (sk) 2005-04-01
KR20040107520A (ko) 2004-12-20
DE60300021T2 (de) 2005-09-08
DE60300021D1 (de) 2004-09-16
PL372724A1 (en) 2005-07-25
AU2003230245A1 (en) 2003-12-02
US6696468B2 (en) 2004-02-24
CN1653063A (zh) 2005-08-10
EP1362857A1 (en) 2003-11-19
ES2227500T3 (es) 2005-04-01
EP1362857B1 (en) 2004-08-11
IL165012A0 (en) 2005-12-18
RU2004136853A (ru) 2005-06-27
DK1362857T3 (da) 2004-12-20
CZ20041084A3 (cs) 2005-02-16

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