TR200606411T1 - Vajinite karşı bir triazol içeren bileşimler. - Google Patents
Vajinite karşı bir triazol içeren bileşimler.Info
- Publication number
- TR200606411T1 TR200606411T1 TR2006/06411T TR200606411T TR200606411T1 TR 200606411 T1 TR200606411 T1 TR 200606411T1 TR 2006/06411 T TR2006/06411 T TR 2006/06411T TR 200606411 T TR200606411 T TR 200606411T TR 200606411 T1 TR200606411 T1 TR 200606411T1
- Authority
- TR
- Turkey
- Prior art keywords
- vaginitis
- compositions
- active ingredients
- compound effective
- effective against
- Prior art date
Links
- 206010046914 Vaginal infection Diseases 0.000 title abstract 4
- 239000000203 mixture Substances 0.000 title abstract 4
- 201000008100 Vaginitis Diseases 0.000 title abstract 3
- 150000003852 triazoles Chemical class 0.000 title 1
- 239000004480 active ingredient Substances 0.000 abstract 2
- 239000003364 biologic glue Substances 0.000 abstract 2
- HJLSLZFTEKNLFI-UHFFFAOYSA-N Tinidazole Chemical compound CCS(=O)(=O)CCN1C(C)=NC=C1[N+]([O-])=O HJLSLZFTEKNLFI-UHFFFAOYSA-N 0.000 abstract 1
- 239000000853 adhesive Substances 0.000 abstract 1
- 230000001070 adhesive effect Effects 0.000 abstract 1
- 239000003242 anti bacterial agent Substances 0.000 abstract 1
- 230000000843 anti-fungal effect Effects 0.000 abstract 1
- 230000000842 anti-protozoal effect Effects 0.000 abstract 1
- 229940121375 antifungal agent Drugs 0.000 abstract 1
- 239000003429 antifungal agent Substances 0.000 abstract 1
- 239000003904 antiprotozoal agent Substances 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000003111 delayed effect Effects 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 210000004877 mucosa Anatomy 0.000 abstract 1
- 244000309462 non-albicans Candida Species 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- 229960005053 tinidazole Drugs 0.000 abstract 1
- 230000000699 topical effect Effects 0.000 abstract 1
- -1 triazole compound Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4168—1,3-Diazoles having a nitrogen attached in position 2, e.g. clonidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4166—1,3-Diazoles having oxo groups directly attached to the heterocyclic ring, e.g. phenytoin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4174—Arylalkylimidazoles, e.g. oxymetazolin, naphazoline, miconazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4196—1,2,4-Triazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
- A61K9/0036—Devices retained in the vagina or cervix for a prolonged period, e.g. intravaginal rings, medicated tampons, medicated diaphragms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/02—Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Reproductive Health (AREA)
- Organic Chemistry (AREA)
- Gynecology & Obstetrics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Urology & Nephrology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Endocrinology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
Buluş vajinal enfeksiyonların, örneğin vajinitin tedavisinde topikal uygulamaya yönelik farmasötik bileşimler sunmaktadır. Bu bileşimler (i) Candidiaalbicans 'a karşı etkili en az bir triazol bileşiği, tercihen ayrıca albicans olmayan Candida türlerinin birine veya daha fazlasına karşı da etkili olan bu tür en az bir bileşik, ve (ü) vajinite karşı en az bir ek ilaç, tercihen antifungal, antiprotozoal ve/veya antibakteriyel bir madde içermektedir. Tercih edilen bileşimler etken maddeler olarak tinidazol ve/veya tiokonazolle kombine olarak terkonazol içerir. Başka bir yönüyle buluşa uygun bileşimler ayrıca vajina mukozasına yapışmayı teşvik etmek için biyolojik yapışkan bir madde, örneğin bir mukoza yapışkanı içerir. Biyolojik yapışkanın kullanılması ayrıca etken maddelerin kontrollü, örneğin hızlı ve/veya geciktirilmiş (sürekli) şahmını da temin edebilir.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0405406.0A GB0405406D0 (en) | 2004-03-10 | 2004-03-10 | Anti-vaginitis compositions |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TR200606411T1 true TR200606411T1 (tr) | 2007-01-22 |
Family
ID=32117416
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TR2006/06411T TR200606411T1 (tr) | 2004-03-10 | 2004-09-17 | Vajinite karşı bir triazol içeren bileşimler. |
Country Status (7)
| Country | Link |
|---|---|
| CN (1) | CN1960763A (tr) |
| BR (1) | BRPI0418623A (tr) |
| EA (1) | EA011952B1 (tr) |
| GB (1) | GB0405406D0 (tr) |
| PL (1) | PL380815A1 (tr) |
| TR (1) | TR200606411T1 (tr) |
| WO (1) | WO2005087270A1 (tr) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060140990A1 (en) * | 2003-09-19 | 2006-06-29 | Drugtech Corporation | Composition for topical treatment of mixed vaginal infections |
| AU2004274000B2 (en) | 2003-09-19 | 2009-07-30 | Drugtech Corporation | Pharmaceutical delivery system |
| CA2617106A1 (en) * | 2005-08-12 | 2007-02-22 | Drugtech Corporation | Estrogen compositions and therapeutic methods of use thereof |
| WO2007079391A2 (en) * | 2006-01-05 | 2007-07-12 | Drugtech Corporation | Drug delivery system for bioadhesion to a vulvovaginal surface |
| CN101374501A (zh) * | 2006-01-05 | 2009-02-25 | 药物技术公司 | 组合物及其使用方法 |
| US9211286B2 (en) * | 2006-09-12 | 2015-12-15 | Curatek Pharmaceuticals Holding, Inc. | Terconazole composition and method |
| US10758630B2 (en) | 2010-08-13 | 2020-09-01 | The Johns Hopkins University | Topical compositions and methods of detection and treatment |
| CN102091097B (zh) * | 2011-01-28 | 2013-04-03 | 武汉耦合医学科技有限责任公司 | 一种免冲洗产妇会阴医疗护理凝胶及其制备方法 |
| IT1403661B1 (it) | 2011-01-28 | 2013-10-31 | Probiotical Spa | Composizione effervescente in forma solida per uso in applicazioni vaginali per il trattamento di infezioni vaginali. |
| ITMI20110792A1 (it) | 2011-05-09 | 2012-11-10 | Probiotical Spa | Ceppi di batteri appartenenti al genere bifidobacterium per uso nel trattamento della ipercolesterolemia. |
| ITMI20110791A1 (it) | 2011-05-09 | 2012-11-10 | Probiotical Spa | Ceppi di batteri in grado di metabolizzare gli ossalati. |
| ITMI20111718A1 (it) | 2011-09-23 | 2013-03-24 | Probiotical Spa | Un materiale impermeabile alla umidita e allo ossigeno per confezionare prodotti dietetici, cosmetici e specialita medicinali. |
| WO2014026707A1 (en) | 2012-08-13 | 2014-02-20 | Edko Pazarlama Tanitim Ticaret Limited Sirketi | Anti-vaginitis compositions with improved release and adherence |
| WO2014027006A1 (en) | 2012-08-13 | 2014-02-20 | Edko Pazarlama Tanitim Ticaret Limited Sirketi | Bioadhesive formulations for use in drug delivery |
| ITMI20130793A1 (it) | 2013-05-14 | 2014-11-15 | Probiotical Spa | Composizione comprendente batteri lattici per uso nel trattamento preventivo e/o curativo delle cistiti ricorrenti. |
| US9446024B2 (en) * | 2013-06-25 | 2016-09-20 | UNIVERSITé LAVAL | Formulations for the treatment of vaginal disorders |
| KR102587444B1 (ko) | 2015-09-29 | 2023-10-11 | 킴벌리-클라크 월드와이드, 인크. | 미생물총의 건강한 균형을 유지하기 위한 상승 조성물 |
| ITUA20162013A1 (it) | 2016-03-24 | 2017-09-24 | Probiotical Spa | Composizione a base di batteri lattici per il trattamento contemporaneo di infezioni vaginali di origine micotica e batterica. |
| MX389431B (es) | 2017-02-28 | 2025-03-20 | Kimberly Clark Co | Composicion sinergica para el mantenimiento del equilibrio saludable de la microflora. |
| WO2021154188A1 (en) * | 2020-01-31 | 2021-08-05 | Exeltis Ilac Sanayii Ve Ticaret Anonim Sirketi | Pharmaceutical composition suitable for vaginal delivery |
| US11529346B2 (en) * | 2020-06-18 | 2022-12-20 | National Medical Supply, LLC | Vaginal gel |
| CN111759840B (zh) * | 2020-07-20 | 2021-05-11 | 温州市人民医院 | 一种防治心肌缺血的药物组合物及其制备方法和用途 |
| CN112190541A (zh) * | 2020-09-27 | 2021-01-08 | 安婕妤化妆品科技股份有限公司 | 一种私密护理凝胶产品 |
| CN112245657B (zh) * | 2020-10-19 | 2022-07-01 | 合肥中科智远生物科技有限公司 | 一种低放热抗菌骨水泥及其制备方法与应用 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5663208A (en) * | 1991-03-01 | 1997-09-02 | Warner-Lambert Company | Antifungal wound healing compositions and methods for preparing and using same |
| CA2177682C (en) * | 1993-12-23 | 1999-12-28 | Sekhar Mitra | Antimicrobial wipe compositions |
| GB9610359D0 (en) * | 1996-05-17 | 1996-07-24 | Edko Trading Representation | Pharmaceutical compositions |
| US20030073646A1 (en) * | 1997-01-22 | 2003-04-17 | Marton Milankovits | Pharmaceutical compositions primarily for the treatment of genitourinary infections |
| US6416779B1 (en) * | 1997-06-11 | 2002-07-09 | Umd, Inc. | Device and method for intravaginal or transvaginal treatment of fungal, bacterial, viral or parasitic infections |
| FR2777783A1 (fr) * | 1998-04-24 | 1999-10-29 | Innothera Lab Sa | Association pharmaceutique d'imidazoles pour le traitement local des vulvo-vaginites infectieuses et des vaginoses |
-
2004
- 2004-03-10 GB GBGB0405406.0A patent/GB0405406D0/en not_active Ceased
- 2004-09-17 CN CNA2004800430095A patent/CN1960763A/zh active Pending
- 2004-09-17 BR BRPI0418623-0A patent/BRPI0418623A/pt not_active IP Right Cessation
- 2004-09-17 TR TR2006/06411T patent/TR200606411T1/tr unknown
- 2004-09-17 PL PL380815A patent/PL380815A1/pl not_active Application Discontinuation
- 2004-09-17 EA EA200601647A patent/EA011952B1/ru not_active IP Right Cessation
- 2004-09-17 WO PCT/GB2004/003972 patent/WO2005087270A1/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| GB0405406D0 (en) | 2004-04-21 |
| EA011952B1 (ru) | 2009-06-30 |
| PL380815A1 (pl) | 2007-03-19 |
| EA200601647A1 (ru) | 2007-02-27 |
| BRPI0418623A (pt) | 2007-05-29 |
| WO2005087270A1 (en) | 2005-09-22 |
| CN1960763A (zh) | 2007-05-09 |
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