TR201307748A2 - Tırnak mantarının topikal tedavisi için formülasyon geliştirilmesi. - Google Patents

Tırnak mantarının topikal tedavisi için formülasyon geliştirilmesi.

Info

Publication number
TR201307748A2
TR201307748A2 TR2013/07748A TR201307748A TR201307748A2 TR 201307748 A2 TR201307748 A2 TR 201307748A2 TR 2013/07748 A TR2013/07748 A TR 2013/07748A TR 201307748 A TR201307748 A TR 201307748A TR 201307748 A2 TR201307748 A2 TR 201307748A2
Authority
TR
Turkey
Prior art keywords
onychomycosis
treatment
ungual
design
terbinafine hydrochloride
Prior art date
Application number
TR2013/07748A
Other languages
English (en)
Inventor
Özgen Özer Kevser
Tuncay Tanriverdi̇ Saki̇ne
Original Assignee
Ege Ueniversitesi
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ege Ueniversitesi filed Critical Ege Ueniversitesi
Priority to TR2013/07748A priority Critical patent/TR201307748A2/tr
Priority to PCT/TR2014/000228 priority patent/WO2014209246A1/en
Publication of TR201307748A2 publication Critical patent/TR201307748A2/tr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7007—Drug-containing films, membranes or sheets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7015—Drug-containing film-forming compositions, e.g. spray-on
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Emergency Medicine (AREA)
  • Inorganic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)

Abstract

Onikomikoz sistemik olarak kullanılan Terbinafin hidroklomr ile tedavi edilebilmektedir Fakat sistemik tedavi sonucu ortaya çıkan yan etkiler topikal tedaviyi gerekli kılmaktadır Tırnak plağının güçlü bariyer yapısı topikal tedavinin etkinliğini azaltmaktadır Bu çalışmada, onikomikozun ungual tedavisi için Terbinafin hidroklorür içeren lipozom formulasyonun yüklü olduğu Pullulan film formülasyonu tasarlanmıştır.
TR2013/07748A 2013-06-27 2013-06-27 Tırnak mantarının topikal tedavisi için formülasyon geliştirilmesi. TR201307748A2 (tr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
TR2013/07748A TR201307748A2 (tr) 2013-06-27 2013-06-27 Tırnak mantarının topikal tedavisi için formülasyon geliştirilmesi.
PCT/TR2014/000228 WO2014209246A1 (en) 2013-06-27 2014-06-27 Design of terbinafine hydrochloride loaded liposome included pullulan film system for ungual treatment of onychomycosis

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
TR2013/07748A TR201307748A2 (tr) 2013-06-27 2013-06-27 Tırnak mantarının topikal tedavisi için formülasyon geliştirilmesi.

Publications (1)

Publication Number Publication Date
TR201307748A2 true TR201307748A2 (tr) 2014-09-22

Family

ID=51398840

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2013/07748A TR201307748A2 (tr) 2013-06-27 2013-06-27 Tırnak mantarının topikal tedavisi için formülasyon geliştirilmesi.

Country Status (2)

Country Link
TR (1) TR201307748A2 (tr)
WO (1) WO2014209246A1 (tr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2018189587A1 (en) 2017-04-14 2018-10-18 Capsugel Belgium Nv Process for making pullulan
CA3059527A1 (en) 2017-04-14 2018-10-18 Capsugel Belgium Nv Pullulan capsules
RU2706115C1 (ru) * 2018-11-19 2019-11-14 Николай Андреевич Комиссаренко Противогрибковое и антимикробное средство комплексного действия
CN113262310A (zh) * 2021-03-02 2021-08-17 宿迁市第一人民医院 一种普鲁兰多糖修饰的人参皂苷Rg3纳米结构脂质载体及其制作方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010086726A1 (en) * 2009-01-30 2010-08-05 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Compositions for nail and skin treatment

Also Published As

Publication number Publication date
WO2014209246A1 (en) 2014-12-31

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