TR201820780A2 - Hayvan hastaliklarina karşi hücresel ve hümoral bağişiklik artirici çoklu faz emülsi̇yon aşi adjuvani - Google Patents

Hayvan hastaliklarina karşi hücresel ve hümoral bağişiklik artirici çoklu faz emülsi̇yon aşi adjuvani Download PDF

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Publication number
TR201820780A2
TR201820780A2 TR2018/20780A TR201820780A TR201820780A2 TR 201820780 A2 TR201820780 A2 TR 201820780A2 TR 2018/20780 A TR2018/20780 A TR 2018/20780A TR 201820780 A TR201820780 A TR 201820780A TR 201820780 A2 TR201820780 A2 TR 201820780A2
Authority
TR
Turkey
Prior art keywords
vaccine adjuvant
phase emulsion
cellular
adjuvant
immunity against
Prior art date
Application number
TR2018/20780A
Other languages
English (en)
Inventor
Büyükbayram Muhammet
Original Assignee
Reakim Enduestriyel Performans Katkilari Kimyevi Maddeler Sanayi Ve Ticaret Ltd Sti
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Reakim Enduestriyel Performans Katkilari Kimyevi Maddeler Sanayi Ve Ticaret Ltd Sti filed Critical Reakim Enduestriyel Performans Katkilari Kimyevi Maddeler Sanayi Ve Ticaret Ltd Sti
Priority to TR2018/20780A priority Critical patent/TR201820780A2/tr
Publication of TR201820780A2 publication Critical patent/TR201820780A2/tr
Priority to PCT/TR2019/051208 priority patent/WO2020139298A2/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/113—Multiple emulsions, e.g. oil-in-water-in-oil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/02—Medicinal preparations containing materials or reaction products thereof with undetermined constitution from inanimate materials
    • A61K35/04—Tars; Bitumens; Mineral oils; Ammonium bituminosulfonate
    • A61K35/06—Mineral oils, e.g. paraffinic oils or aromatic oils based on aromatic hydrocarbons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Dispersion Chemistry (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Dermatology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

Buluş, veterinerlik alanında hayvan sağlığının korunması amacı ile kullanılan aşı adjuvanı ile ilgilidir. Bahsedilen adjuvan, kullanımında hümoral ve hücresel bağışıklığı artırıcı etki göstermektedir. Buluşa konu adjuvan aynı zamanda, aşıların raf ömrünü artırdığı, çoklu faz emülsiyonu sayesinde aşılara çok daha uzun kullanım süresi kazandırmaktadır. Bahsedilen aşı adjuvanı, farmasötik mineral yağ, yüzey aktif maddeler ve bitkilerden saflaştırılmış liyofilize katkılar içermektedir.
TR2018/20780A 2018-12-27 2018-12-27 Hayvan hastaliklarina karşi hücresel ve hümoral bağişiklik artirici çoklu faz emülsi̇yon aşi adjuvani TR201820780A2 (tr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
TR2018/20780A TR201820780A2 (tr) 2018-12-27 2018-12-27 Hayvan hastaliklarina karşi hücresel ve hümoral bağişiklik artirici çoklu faz emülsi̇yon aşi adjuvani
PCT/TR2019/051208 WO2020139298A2 (en) 2018-12-27 2019-12-25 Cellular and humoral immunity augmenter multiple phase emulsion vaccine adjuvant against animal diseases

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
TR2018/20780A TR201820780A2 (tr) 2018-12-27 2018-12-27 Hayvan hastaliklarina karşi hücresel ve hümoral bağişiklik artirici çoklu faz emülsi̇yon aşi adjuvani

Publications (1)

Publication Number Publication Date
TR201820780A2 true TR201820780A2 (tr) 2019-03-21

Family

ID=67980158

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2018/20780A TR201820780A2 (tr) 2018-12-27 2018-12-27 Hayvan hastaliklarina karşi hücresel ve hümoral bağişiklik artirici çoklu faz emülsi̇yon aşi adjuvani

Country Status (2)

Country Link
TR (1) TR201820780A2 (tr)
WO (1) WO2020139298A2 (tr)

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0059521B1 (en) * 1981-03-03 1985-01-02 Centraal Diergeneeskundig Instituut Water-in-oil emulsion for use in the potentation of the immune system of animals
JP3814290B2 (ja) * 1993-12-09 2006-08-23 エスクナー，ハインリッヒ 抗原用のアジュバントおよびその製法ならびに用途
CN105854013B (zh) * 2015-01-22 2019-06-07 中牧实业股份有限公司 一种动物疫苗油佐剂及其动物疫苗
CN106692966B (zh) * 2015-07-29 2020-10-13 刘卓灵 动物疫苗用佐剂及其制备方法和应用
CN108014104A (zh) * 2018-01-22 2018-05-11 青岛科技大学 一种增效型二氢杨梅素可溶型复合物及其制备方法

Also Published As

Publication number Publication date
WO2020139298A2 (en) 2020-07-02
WO2020139298A3 (en) 2020-08-13

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