TR201907241T4 - IL-17 inhibitörü terapisi etkinliği için bir biyo-işaret olarak lipokalin 2. - Google Patents

IL-17 inhibitörü terapisi etkinliği için bir biyo-işaret olarak lipokalin 2. Download PDF

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Publication number
TR201907241T4
TR201907241T4 TR2019/07241T TR201907241T TR201907241T4 TR 201907241 T4 TR201907241 T4 TR 201907241T4 TR 2019/07241 T TR2019/07241 T TR 2019/07241T TR 201907241 T TR201907241 T TR 201907241T TR 201907241 T4 TR201907241 T4 TR 201907241T4
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TR
Turkey
Prior art keywords
lipocalin
biomarker
inhibitor therapy
therapy efficacy
efficacy
Prior art date
Application number
TR2019/07241T
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English (en)
Inventor
Samuel Platt Adam
Edward Rapecki Stephen
Fortunato Mara
Leigh Rundle Jon
Alfred Smith Paul
Sairfull Watt Gillian
Original Assignee
Ucb Biopharma Sprl
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ucb Biopharma Sprl filed Critical Ucb Biopharma Sprl
Publication of TR201907241T4 publication Critical patent/TR201907241T4/tr

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6863—Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
    • G01N33/6869—Interleukin
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/564—Immunoassay; Biospecific binding assay; Materials therefor for pre-existing immune complex or autoimmune disease, i.e. systemic lupus erythematosus, rheumatoid arthritis, multiple sclerosis, rheumatoid factors or complement components C1-C9
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/52—Assays involving cytokines
    • G01N2333/54—Interleukins [IL]
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Rehabilitation Therapy (AREA)
  • Rheumatology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Mevcut buluş IL-17'nin aracılık ettiği hastalıklar için ve bir hastanın anti-IL-17 terapisi cevabını izlemek için bir biyo-işaret olarak lipokalin 2'nin (LCN2) kullanımını sağlamaktadır.
TR2019/07241T 2011-01-07 2012-01-09 IL-17 inhibitörü terapisi etkinliği için bir biyo-işaret olarak lipokalin 2. TR201907241T4 (tr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB1100282.1A GB201100282D0 (en) 2011-01-07 2011-01-07 Biological methods

Publications (1)

Publication Number Publication Date
TR201907241T4 true TR201907241T4 (tr) 2019-06-21

Family

ID=43663952

Family Applications (1)

Application Number Title Priority Date Filing Date
TR2019/07241T TR201907241T4 (tr) 2011-01-07 2012-01-09 IL-17 inhibitörü terapisi etkinliği için bir biyo-işaret olarak lipokalin 2.

Country Status (5)

Country Link
EP (2) EP2661627B1 (tr)
ES (1) ES2728253T3 (tr)
GB (1) GB201100282D0 (tr)
TR (1) TR201907241T4 (tr)
WO (1) WO2012093254A1 (tr)

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WO2017136497A1 (en) * 2016-02-03 2017-08-10 The Cleveland Clinic Foundation Detection and treatment of il-17 and il-13 related conditions
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Also Published As

Publication number Publication date
ES2728253T3 (es) 2019-10-23
EP2661627B1 (en) 2019-03-13
EP2661627A1 (en) 2013-11-13
GB201100282D0 (en) 2011-02-23
EP3534159A1 (en) 2019-09-04
WO2012093254A1 (en) 2012-07-12

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