TR201914420A2 - Sapropteri̇n di̇hi̇droklorür ve en az bi̇r anti̇oksi̇dan i̇çeren farmasöti̇k formülasyonlar - Google Patents
Sapropteri̇n di̇hi̇droklorür ve en az bi̇r anti̇oksi̇dan i̇çeren farmasöti̇k formülasyonlar Download PDFInfo
- Publication number
- TR201914420A2 TR201914420A2 TR2019/14420A TR201914420A TR201914420A2 TR 201914420 A2 TR201914420 A2 TR 201914420A2 TR 2019/14420 A TR2019/14420 A TR 2019/14420A TR 201914420 A TR201914420 A TR 201914420A TR 201914420 A2 TR201914420 A2 TR 201914420A2
- Authority
- TR
- Turkey
- Prior art keywords
- antioxidant
- pharmaceutical formulations
- formulations containing
- sapropterin dihydrochloride
- containing sapropterin
- Prior art date
Links
- 239000003963 antioxidant agent Substances 0.000 title abstract 2
- 230000003078 antioxidant effect Effects 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 229960004209 sapropterin dihydrochloride Drugs 0.000 title abstract 2
- RKSUYBCOVNCALL-NTVURLEBSA-N sapropterin dihydrochloride Chemical compound Cl.Cl.N1=C(N)NC(=O)C2=C1NC[C@H]([C@@H](O)[C@@H](O)C)N2 RKSUYBCOVNCALL-NTVURLEBSA-N 0.000 title abstract 2
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Medicinal Preparation (AREA)
Abstract
Mevcut buluş, sapropterin dihidroklorür ve en az bir antioksidan içeren farmasötik formülasyonlarla ilgilidir.
Priority Applications (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| TR2019/14420A TR201914420A2 (tr) | 2019-09-23 | 2019-09-23 | Sapropteri̇n di̇hi̇droklorür ve en az bi̇r anti̇oksi̇dan i̇çeren farmasöti̇k formülasyonlar |
| PCT/TR2020/050690 WO2021061067A1 (en) | 2019-09-23 | 2020-08-05 | Pharmaceutical formulations comprising sapropterin dihydrochloride and at least one antioxidant |
| EP20868726.9A EP4034126A4 (en) | 2019-09-23 | 2020-08-05 | PHARMACEUTICAL FORMULATIONS COMPRISING SAPROPTERIN HYDROCHLORIDE AND AT LEAST ONE ANTIOXIDANT |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| TR2019/14420A TR201914420A2 (tr) | 2019-09-23 | 2019-09-23 | Sapropteri̇n di̇hi̇droklorür ve en az bi̇r anti̇oksi̇dan i̇çeren farmasöti̇k formülasyonlar |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TR201914420A2 true TR201914420A2 (tr) | 2021-04-21 |
Family
ID=75167041
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TR2019/14420A TR201914420A2 (tr) | 2019-09-23 | 2019-09-23 | Sapropteri̇n di̇hi̇droklorür ve en az bi̇r anti̇oksi̇dan i̇çeren farmasöti̇k formülasyonlar |
Country Status (3)
| Country | Link |
|---|---|
| EP (1) | EP4034126A4 (tr) |
| TR (1) | TR201914420A2 (tr) |
| WO (1) | WO2021061067A1 (tr) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2025053806A1 (en) * | 2023-09-08 | 2025-03-13 | Ilko Ilac Sanayi Ve Ticaret A.S. | Sapropterin soluble tablet composition |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BRPI0517088A (pt) * | 2004-11-17 | 2008-09-30 | Biomarin Pharm Inc | formulação de comprimido estável |
| WO2008089148A1 (en) * | 2007-01-12 | 2008-07-24 | Biomarin Pharmaceutical Inc. | Method of treating a metabolic or neuropsychiatry disorder with a bh4 derivative prodrug |
| KR20140021585A (ko) * | 2011-03-01 | 2014-02-20 | 루비콘 리서치 피브이티. 엘티디. | 테트라하이드로바이옵테린의 안정한 조성물 |
| US9216178B2 (en) * | 2011-11-02 | 2015-12-22 | Biomarin Pharmaceutical Inc. | Dry blend formulation of tetrahydrobiopterin |
| CN104257623A (zh) * | 2014-09-09 | 2015-01-07 | 广东中盛药物研究院有限公司 | 一种含盐酸沙丙蝶呤的泡腾片 |
-
2019
- 2019-09-23 TR TR2019/14420A patent/TR201914420A2/tr unknown
-
2020
- 2020-08-05 WO PCT/TR2020/050690 patent/WO2021061067A1/en not_active Ceased
- 2020-08-05 EP EP20868726.9A patent/EP4034126A4/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| EP4034126A4 (en) | 2023-10-18 |
| WO2021061067A1 (en) | 2021-04-01 |
| EP4034126A1 (en) | 2022-08-03 |
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