TW200640868A - 5-Substituted quinoline and isoquinoline derivatives, a process for their production and their use as anti-inflammatory agents - Google Patents

5-Substituted quinoline and isoquinoline derivatives, a process for their production and their use as anti-inflammatory agents

Info

Publication number
TW200640868A
TW200640868A TW095104625A TW95104625A TW200640868A TW 200640868 A TW200640868 A TW 200640868A TW 095104625 A TW095104625 A TW 095104625A TW 95104625 A TW95104625 A TW 95104625A TW 200640868 A TW200640868 A TW 200640868A
Authority
TW
Taiwan
Prior art keywords
production
inflammatory agents
substituted quinoline
isoquinoline derivatives
isoquinoline
Prior art date
Application number
TW095104625A
Other languages
Chinese (zh)
Inventor
Stefan Jaroch
Werner Skuballa
Hartmut Rehwinkel
Norbert Schmees
Heike Schacke
Orlin Petrov
Matthias Schneider
Christian Dinter
Original Assignee
Schering Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag filed Critical Schering Ag
Publication of TW200640868A publication Critical patent/TW200640868A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Rheumatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Compounds of general formula (IIa) or (IIb), and their use as pharmaceutical agents.
TW095104625A 2005-04-26 2006-02-10 5-Substituted quinoline and isoquinoline derivatives, a process for their production and their use as anti-inflammatory agents TW200640868A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE102005020331A DE102005020331A1 (en) 2005-04-26 2005-04-26 New 5-substituted quinoline and isoquinoline derivatives are glucocorticoid receptor binders useful for treating inflammatory diseases e.g. alveolitis, Sjogren's syndrome, atopic dermatitis, acute lymphatic leukemia, rhinitis and emesis

Publications (1)

Publication Number Publication Date
TW200640868A true TW200640868A (en) 2006-12-01

Family

ID=37085142

Family Applications (1)

Application Number Title Priority Date Filing Date
TW095104625A TW200640868A (en) 2005-04-26 2006-02-10 5-Substituted quinoline and isoquinoline derivatives, a process for their production and their use as anti-inflammatory agents

Country Status (2)

Country Link
DE (1) DE102005020331A1 (en)
TW (1) TW200640868A (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20080171873A1 (en) * 2007-01-12 2008-07-17 Harms Arthur E Synthesis of selected stereoisomers of certain substituted alcohols

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UA80120C2 (en) * 2002-03-26 2007-08-27 Boehringer Ingelheim Pharma Glucocorticoid mimetics, pharmaceutical composition based thereon
DE10215316C1 (en) * 2002-04-02 2003-12-18 Schering Ag Quinoline and isoquinoline derivatives, a pharmaceutical agent and their use as anti-inflammatory agents

Also Published As

Publication number Publication date
DE102005020331A1 (en) 2006-11-02

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