TW200836629A - Insecticidal composition for seeds or harvested crops and method for using the same - Google Patents

Abstract

The present invention is to provide a novel insecticidal composition for seeds or harvested crops and a novel method for preventing damage by various insects in seeds or harvested crops of a plant for agriculture. Disclosed is an insecticidal composition, in which compounds represented by the general fomula (1) or (5) are contained as active ingredients and a method for preventing damage by an insect, in which the composition is applied to seeds or harvested crops of a plant for agriculture.

Description

200836629 IX. Description of the invention: [Technical field to which the invention pertains] = The invention relates to a novel insecticidal composition, and a novel method for preventing insect pests, which is to turn the pests into plant seeds or agricultural plants. Harvesting and preventing pests. [Prior Art] International Publication No. 2 GG5/G21488 and International Publication No. 2 ()_73165 have records of insecticides and methods of use thereof. And 'the past silk _ in the plant seeds to test the insecticide, beneficial to the amine

Litpnd), thiamethoxiam, fentanyl (tetra), dicing agent, etc., are known to be applied to the seed by spraying, smearing, soaking or powder coating. Patent Document 1: International Publication No. 2005/021488, pamphlet Patent Document 2: International Publication No. 2〇〇5/〇73165, Volume [Invention] (The problem to be solved by the invention) is that the aforementioned insecticidal prevention in forest can be prevented. Or difficult to prevent the silk. The second objective is to provide a new insecticidal composition and to prevent various pests from preventing various pests in plant seeds or harvests of agricultural plants. In order to solve the above problems, we found that one or two of the compounds represented by the formula (5) were used to prevent the harvest of plant seeds or agricultural plants. Pests are the completion of the present invention. In other words, the present invention is as follows. (4) A compound containing one or more compounds of the compound represented by the formula (1) as a ruthenium of the compound of the formula (1). 2 N, (Χ)η (1) ♦X. In the formula i', Ai, A2, A3, and A4 each represent a stone atom, a nitrogen atom, and an anti-atomic, nitrogen atom or an oxidized one independently represents a hydrogen atom, C1-C4, p

Gi, independently of each other, represents an oxygen atom or a sulfur atom, a C4 group, and x may be the same or different, meaning hydrogen eyebrow early 'trifluoromethyl, 4 atom, self atom, Cl - C3 alkyl or n An integer from 0 to 4,

Qi represents a phenyl group, a substituted phenyl group: a C1-C4 filament selected from a halogen atom, a C1-r | group = a C2 to a C4 thin group, a cf halogen, a Ci, an S: C4ri alkynyl group, a C3 -C8 cycloalkyl, C3-C8*cycloalkane A, C3-halomethoxy, C1-C3 sulphur, C1-halo, guar, Cl-C3 alkylsulfinyl, C1-C3 Alkylsulfinyl, C1-C3 sulphonyl, Cl-C3, fluorenyl, C1-C4 acryl, di-C1 C4 aminyl, amine, cyano, nitro, thiol, C1-C4 burnt Wei, C1 ~ C4 halogenated carbonyl, C1-C4 alkoxycarbonyl, C1-C4 halocarbonyloxy, cl-C4 alkoxycarbonyl, ci-C4 i alkoxycarbonyl, C1-C4 alkane Carbonyl group, C1-C4 halogenated carbonylamino group, Cl-C4 alkyl sulphate, ci-C4 halogenated fluorenyl fluorenyloxy, arylsulfonyloxy, pentafluorosulfanyl, benzynyl or One or more substituents which are the same or different among the phenyl groups, a carbocyclic group (wherein the carbocyclic group represents a naphthyl group, a tetradecylnaphthyl group, a dihydroindenyl group, a fluorenyl group, a 9-side oxyalkyl group, a diamond Alkyl, fluorenyl or fluorenyl.), substituted carbocyclyl: selected from a halogen atom, C1-C4 leukoxene, C1-C 4 halo group, substituted C1-C4 alkyl, C2-C4 alkenyl, C2-C4 haloalkenyl, 200836629 C2-C4 block, C2-C4 halo block, C3 - C8 cycloalkyl, C3 - C8 _cycloalkyl, Cl -C3 alkoxy, C1-C3 i alkoxy, C1-C3 alkylthio, C1-C3 thiol, C1 - C3 alkyl sulfinyl, C1 - C3 i Alkyl sulfinyl, Cl—C3, sulphate, C1—C3 haloalkyl fluorenyl, C1—C4 alkylamino, di C1-C4 acryl, amine, cyano, nitro, hydroxy, C1-C4 alkane Carbonyl group, α-C4, aryl group, C1-C4 alkoxycarbonyl group, C1_C4 haloalkylcarbonyloxy group, ci-C4 alkoxy group, C1-C4-burning oxygen group, C1-C4 alkanoamine group, a C1_C4 group, a C1-C4 alkyl group, an oxygen group, a C1-C4 halogen group sulfomethoxy group, an aryl group 1~amp; an oxy group, a pentafluorosulfanyl group, a phenyl alkynyl group or a phenyl group, the same or different ones The above substituent (wherein the carbocyclic group represents a naphthyl group, a tetrahydronaphthyl group, an indanyl group, a fluorenyl group, a 9-membered fluorenyl group, an adamantyl group, a fluorenyl group or a fluorenyl group), % base (the heterocyclic group here means pyridinyl, pyridyl, N__oxidized pyridyl, ° dense Biting base, material base, sulphonyl group, age-based fluorenyl group L-recorded dimercapto group, oxazolyl, isotazolyl, oxadiazolyl, α-l-butyryl, imidazolyl, triazolyl, H, oxime, benzo-yl, benzo-, benzo-S-furanyl, benzo, phenyl, fluorenyl, iso-kilo, f-radical, iso-yl, 1-indole / / 2, benzo, benzo [1,3] dibasic, tetrahydro (tetra), acridinyl or dihydropyranyl. ), or generation: having a source derived from a γ atom, a C1 to C4 alkyl group, a C1-C4 halogen group, a substituted C1-C4 wire, a C2-C4 _C2-C4 alkynyl group, a C2-C4 alkynyl group , C3 — 崎基 I η—mouth 丞 丞 C8 垸 、, C 3 —C 8 halocycloalkano, C 1 —C 3 ^ alkoxy, Cl—C 3 alkylthio, C 1 — 3 age base subunit, C Sulfonic acid group, C1-C4 acrylamine group, di-C4 halogen-burning carbonyl group, C1-C4-burning carbonyloxy group, Ci~C4 f J-based di-C1 C4 calcining group, C1-C4 oxidizing wire, C1~C4 group , = calcined amino group, Cl-C4 smectite, C1 gas C1 - c4 aryl sulfonyloxy, pentafluorosulfide, Gumki middle phase 200836629 f generation f (here (four) base対 吻 吻 、 、 、 、 、 、 、 、 、 、 、 、 、 、 、 、 、 、 、 、 、 、 、 、 、 、 、 、 、 、 、 、 、 、 、 、 、 、 、 、 、 、 、 、 、 、 、 、 、 、嗟二哇基,转基,米唾基,三哇^, ° than saliva, Sipu, benzoxyl, benzoyl, benzoheptanyl, i-thienyl, quinolinyl, Isoquinolinyl, fluorenyl, isodecyl, lH-isoindolyl, 2,3-dihydro-benzo[M]dijinjing, benzopyrene 1 Nanxun The base or dihydro-pyran-yl); Cheng fly piece goods South Q2 represents:

a long, cyclic group (wherein the carbocyclic group represents a naphthyl group, a tetrahydronaphthyl group, a C3-C8 cycloalkyl group, a monohydroindenyl group, a fluorenyl group, a 9-side oxyalkyl group, an adamantyl group or a blessing group) Substituted carbocyclic group: having a halogen atom, a C1_C4 alkyl group, a C1-C4 haloalkyl group, a substituted Cl-C4 alkyl group, a C2-C4 alkenyl group, a C2-C4- group, a C2-C4 group Alkynyl, C2-C4 haloalkynyl, C3-C8 cycloalkyl, C3-C8 halocycloalkyl, Cl-C3 alkoxy, C1-C3 ii alkoxy, C1-C3 sulphur, C1-C3 Sulfur-based, ci-C3 alkyl sulfonium, C1 - C3 halogenated sulfastyl sulfhydryl, Cl.-C3 alkylsulfonyl, Cl-C3 haloalkylsulfonyl, C1 -C4 alkylamine , diCl C4 amine group, cyano group, nitro group, thiol group, ci-C4 alkyl group, ci~C4 alkyl alcohol group, C1-C4 alkylcarbonyloxy group, ci-C4 haloalkylcarbonyloxy group, C1 —C4 alkoxycarbonyl, C1—C4 halooxyalkyl, C1-C4 alkanoamine, C1—C4 haloalkylamino, C1-C4 alkyl fluorenyloxy, C1-C4 haloalkyl sulfonate One or more substituents which are the same or different among the decyloxy group, the arylsulfonyloxy group, the pentafluorosulfanyl group or the phenyl group (the stone here) A cyclic group means a naphthyl group, a tetrahydronaphthyl group, a C3-C8 cycloalkyl group, an indanyl group, a carboxyl group, a 9-oxooxy group, an adamantyl group or a ruthenium group.), a heterocyclic group (herein Heterocyclyl means pyridyl, pyridyl, N-oxidized pyridyl, pyrimidinyl, hydrazine, furyl, thienyl, oxazolyl, isoxazolyl, oxadiazolyl, thiazolyl, isothiazole Base, thiadiazolyl, pyrrolyl, imidazolyl, triazolyl, indolozolyl, tetrazolyl, benzothiazolyl, benzoxazolyl, benzofuranyl, benzoxenyl, quinoline , isoquinolinyl fluorenyl, isodecyl, m-isodecyl, 2,3~dihydro-benzo[I,4]diindolyl, benzo[1,3]dioxime Azolyl, tetrahydropyranyl, 200836629, benzoic acid or dinitrocarbenyl.), substituted heterocyclic group · having a halogen atom, a C1 - C4 alkyl group, a C1 - C4 halogen group, Substituted Cl—C4 alkyl, C2-C4 dilute, C2-C4 haloalkenyl, C2-C4 alkynyl, C2-C4 haloalkynyl, fluorene-C8 cycloalkyl, C3-C8 halocycloalkyl, C1 — C3 alkoxy, C1-C3 haloalkoxy, Ci—C3 alkane , α_ C3 halogen-burned squash base, Cl-C3 alkyl sulphate, ci-C3 halogenated sulphate, C1 - C3 sulphate, C1 - C3 halogenated sulphate, C1 - C4 sulphur Base, two C1 - C4, a cyano group, a cyano group, a decyl group, a thio-C4 group, a C1 - C4 group, a C1 - C4 alkylcarbonyl group, a C1 - C4 halocarbonyloxy group , C1 - C4 aerobic acid group, ci-c4 i alkoxycarbonyl group, C1_C4 alkylcarbonylamino group, C1-C4 haloalkylamino group, C1-C4 alkylsulfonyloxy group, C1_C4-alkyl group One or more of the same or different ones of the arylsulfonyloxy group, the pentafluorosulfoxy group or the phenyl group, which means that the t-well is a one-two base. A pyridyl group, a ruthenium group, a furyl group, a thienyl group, a carbazolyl group, an iso-yl group, a commercially available, a fluorenyl group, a hydrazide group, a caffeyl group. m = benzyl oxazolyl, tetrazolyl, benzothiazolyl, benzoxazolyl, benzofuranyl, thienyl, quinolyl, isoquinolinyl, fluorenyl, hydrazino , one out of ^, 2,3-dihydro-benzo[1,4] dioxin, benzo[(3) dioxin & benzobenzimidazolyl or dihydropyranyl. ), 2 甬 甬 C C1 — C6 alkyl, substituted C1-C6 alkyl ·· has selected from halogen atom, α-c C2-C4?, C2-C4. dilute, C2 —... sulfhydryl, C2_C4 Rapid tooth, C3-C8 ring wire, C3-C8 i-ring wire, C1-C3 wire base, a-g Ϊ oxygen C3 sister thio group, C1-macakisulfonyl group, Cl-C3 haloalkyl sulphite醯 醯, C1__C3 alkyl sulphate, C1-c J light base, Cl-C4 amine group, two α.—C4 amine group, 1 group, hetero:, base, C1-C4, several groups, C1— C4 halo, C1-C4 caloxy, ^-C4 halooxy, C1-C4 oxygenated, C1-C4 functional oxygen

-C4 test amine group, Cl-C4 self-burning amine group, α-C46-based hetero-oxygen 1Q 200836629 -C4 halogen-based sapphire yellow oxy group, argon oxy group, domain sulphur sensation or phenyl group the same or different One or more substituents, which are represented by the formula (2):

(2) may be the same or different, indicating (wherein, γι, γ2, γ3, Y4, Y5 氲 atom, halogen atom, C1 - C6 alkyl group, ri wire: having a choice from a lower atom, C1-C3 burning oxygen Base, p its oxygen soil, C1-C3 sulfur-burning group, C1-C3 self-burning sulfur group, α-α ί-based C3 dentate base, C1-C3 sulphonate, it thiol, C1— U-contact group, di-C1-C4 amine group, cyanide "negative", C1-C4 alkylcarbonyl, C1-C4 halocarbonyl, C1-C4 η4 from decyloxy, C1-C4 aerobic group, C1 -C4 卤烧ί Uί U4 alkyl carbonyl hydrazine, C1, alkyl carbonyl amine, C1 - C4 赖 Χ 夕 ^ 美 美 丝 丝 氧基 氧基 氧基 氧基 氧基 氧基 氧基 氧基 氧基 氧基 氧基 氧基 氧基 氧基 氧基 氧基 氧基 氧基 氧基 氧基 氧基 氧基 氧基One or more substituents which are the same or different, ^ ^ c^c4 ' C2~C4^ C6 grafted oxy group, a-C6 _ alkoxy group, clothing '-C8 halocycloalkyl group, C1—, _ alkoxy group : selected from hydrogen atoms, woven, chlorine atoms,

Atom atom, atom, C1-C6 alkoxy 4C1 - C different substituents, (10) C1-C6 haloalkyl which is the same or substituted by one or more hydroxy groups, =1, upper C1-C6 halogen C1-C6 _ silk substituted by alkyl group, 7, or more than one alkoxy-substituted C1-C6 haloalkyl group, <C1-C6 s alkyl substituted by one or more haloalkoxy groups, 200836629 C1 —C6 alkylthio, Cl—C6 haloalkylthio, Moyuan=峨', gas atom, different sulfhydryl or α—“the same in the sharp edge or C1—C6 alkyl sulfinyl, C1 — C6 haloalkyl sulfinyl group, C6 halo alkoxy group is taken from ί-C6 halocarbazide fluorenyl group: 'after selection from hydrogen atom, laughter, fading atom, _ sub, C1-C6 silk base Or ci-i 匕 base, milk

Substituted by the same or different substituents, C1~C6 alkylsulfonyl, C1~C6 haloalkyl fluorenyl, 2nd C1 - C0 haloalkylsulfonyl: selected from hydrogen atom, hydroxyl group '_子, α—(10) oxy or C1-C6 halogen = substituted with one or more substituents of the same or different, dry phase

Cl C4 Oxygenophilic group, ci-C4 halogenated oxygen group, C1-C4 alkaloid, CK4 4 silk amine, C1-C6 silkyxanthine, fluorenyl C1 - C6 haloalkyl sulfonate , C1-C4 alkylcarbonyl, C1_C4 halocarbonyl carbonyl ^i-C4 carbonyloxy, C1_C4 halocarbonyloxy, cyano, nitro, hydroxy = pentafluorosulfanyl, carboxyl, amine sulfhydryl, C1_C3 alkylaminocarbonyl, alkoxy, substituted acridineoxy: having a halogen atom, a C1-C4 alkyl group, a C1-C4 halogen group, a substituted C1_C4 alkyl group, a C2_C4 alkenyl group, a C2 group —C4 halene C2—C4 block, C2-C4 haloalkynyl, C3-C8 cycloalkyl, C3-C8 self-alkyl, C1-C3 alkoxy, C1-C3 haloalkoxy, C1-C3 Alkylthio group, C3 _ sulphur group, C1 - C3 alkyl sulphate, C1 - C3 halogenated sulphate, C1 - C3 alkyl sulphate, ci - C3 haloalkyl sulphate, Cl - C4 Amino, diCl-C4 alkylamino, cyano, nitro, hydroxy, C1-C4 alkylcarbonyl, C1-C4 oxalate, Cl-C4 alkylcarbonyloxy, C1_C4 halocarbonyloxy, ci a C4 alkoxygen 11 200836629 Prison base, Cl-C4 haloalkoxy levy Cl—C4 alkylamine, Cl—C4 haloalkylamine, C1-C4 alkylsulfonyloxy, C1-C4 haloalkylsulfonyloxy, alkyl sulfoxide, pentafluorosulfurate or One or more substituents which are the same or different among the phenyl groups, a phenyl group, a substituted phenyl group: having a halogen atom, a C1-C4 alkyl group, a C1-C4 haloalkyl group, a substituted C1-C4 alkyl group, C2 - C4 alkenyl, C2 - C4 haloalkenyl, C2 - C4 alkynyl, C2 - C4 haloalkynyl, C3 - C8 cycloalkyl, C3 - C8 alkyl (wherein the heteropoly group represents σ ratio) , biting base, Ν-oxidation II than bite, pyrimidinyl, hydrazine, furyl, thienyl, carbazolyl, isoxazolyl, fluorenyl, thiazolyl, isothiazolyl, thiadiazole Base, pyrrolyl, imidazolyl, triazole, ^ sit, tetrafilament, benzoxyl, benzoxanthene, benzopyridin, J-mercapto, Cl-C3 alkoxy, Cl-C3 Haloalkoxy, C1-C3 alkylthio, d C3 halogenated sulfur, Cl - C3 alkyl sulphate, Cl - C3 halogenated sulphate, C1 - C3 alkyl sulfonyl , Cl—C3 haloalkylsulfonyl, C1—C4 acrylamine ΓC1—C 4 alkylamino, cyano, nitro, hydroxy, C1 - C4 alkylcarbonyl, C1 - C4 halocarbonyl, C1 - C4 alkylcarbonyloxy, 〇1 - 4 halocarbonyloxy, 1~〇4 Oxygenated %, C1 - C4 halogenated oxygen group, C1 - C4 burned amine group, Cl - C4 13⁄4 burned amine group, C1: C4 alkylsulfonyloxy group, α-C4 alkyl group One or more substituents which may be the same or different among the oxy group, the pentafluorosulfide group or the phenyl group, a 1 hydrazine-isoindenyl group, a tetrahydropyranyl group or a dihydronenyl group. ), or, thiophene, jinlinji, iso-linyl, yuduji, iso-broadenyl, 2,3-dihydro-benzo[I,4]dioxin, benzo, 3 Dicarbazolyl,

12 200836629

Heterocyclic, pentafluorosulfanyl or stupid heterocyclic ring bombardment: S: C4 carbonyloxy, Cl-C4 halocarbonyloxy, Cl-C4 alkoxy, C1 - C4 alkyl, C1 - C4 ^ aerated carbonyl, Cl - C4 alkylcarbonylamine, (: 1 - 4 haloalkyl carbonyl amine good, C1 - C4 halogenated sulphur yellow oxy, aryl stone yellow oxygen in the same or different More than one substituent (here

^ base, N-oxidation mouth ratio pyridine group, pyridinyl group, 嗒π well base, ke ke group, 嗤 嗤 base, 噚 峻 基 base, 嗤 嗤 base, 嗟 嗟 11 略 基 base, miso base, three Tr sitting group, π-barryl group, tetradecyl group, • olfactyl group, benzofuranyl group, benzothienyl group, quinolyl group, isodecyl group, 1H-isodecyl group, 2,3-dihydrogen Benzene is ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ , C1~C3 alkylthio, C1-C3 _ alkylthio, C1-C3 alkane sulphate, decyl C3 halosulfonyl, ci-C3 alkyl sulfonyl, C1-C3 In the case of burning a basestone or a cyano group, the absence of γ3 means C2-C6 all-gas burned base, C1-C6 perfluorosulfonylthio group, C1-C6 perfluoroalkylsulfinyl group or C1-C6 perfluoroalkyl In the case of a sulfonyl group, or a group represented by the formula (3)

(wherein Y6, Y7, Ys, Y9 may be the same or different and represent a hydrogen atom, a halogen atom, a C1-C6 alkyl group, a ci-C6 haloalkyl group, a C2-C4 alkenyl group, a C2-C4 haloalkenyl group, C2-C4 alkynyl, C2-C4-alkynyl, C3-C8 cycloalkyl, C3-C8 halocycloalkyl, Cl-C4 alkoxy, C1-C4 haloalkoxy, may pass through more than one Substituted C1 - C6 haloalkyl, C1-C6 haloalkyl which may be substituted by one or more alkoxy groups, Cl-C6 haloalkyl group which may be substituted by one or more haloalkoxy groups, Cl-C6 sulfur-burning group , C1 - C6 halogen-burning sulfur group, C1 - C6 alkyl sulphide, C1 - C6 halogenated sulphate, sulphate, C1 - C6 sulphur base sulphate 'Cl - C6 halogenated sulphate sulphate, C1 - C6 13 200836629 Sulfosulfonyloxy, Cl—C6 ialkylsulfonyloxy, Cl—C4 alkylcarbonyl, ci-C4 halocarbonyl, C1-C4 alkoxycarbonyl, C1-C4 halocarbonyloxy, cyano, Sulfhydryl, hydroxy, pentafluorosulfanyl, phenyl, substituted phenyl: having a halogen atom, a C1-C4 alkyl group, a C1-C4 haloalkyl group, a substituted Cl-C4 alkyl group, a C2-C4 group Alkenyl, C2-C4-thinyl, C2-C4 alkynyl C2—C4 haloalkynyl, C3-C8 cycloalkyl, C3-C8 halocycloalkyl, C1-C3 alkoxy, C1-C3 haloalkoxy, C1-C3 alkylthio, C1_C3 halogenated sulfur , Cl—C3 alkyl sulfinyl group, Cl—C3 halogenated sulfite yellow aryl, Cl—C 3 alkyl sulfonyl, C 1 —C 3 haloalkyl sulfonyl, Cl —C 4 decyl fluorene Cl—C4 alkylamino group, cyano group, nitro group, hydroxyl group, C1-C4 alkylcarbonyl group, ct_c4 halogenated carbonyl group, Cl-C4 carbonyloxy group, C1-C4 halogenated carbonyloxy group, C1-C4 alkoxy group , C1 - C4 - alkoxycarbonyl, C1 - C4 alkylcarbonylamino, C1 - C4 halogenated amino group, C1 - C4 alkylsulfonyloxy, C1 - C4 - alkylsulfonyloxy, aromatic One or more substituents f to heterocyclic groups which are the same or different among the oxy group, the pentafluorosulfanyl group or the phenyl group (herein, the heterocyclic group means pyridinyl group, pyridyl group, N-oxidized pyridyl group, Pyridyl, hydrazine, furyl, thienyl, carbazolyl, isoxazolyl, oxadiazolyl, thiazolyl, isothiazolyl, thiadiazolyl, pyrrolyl, imidazolyl, triazole^, Azyl, tetrazolyl, benzothiazolyl, benzoxazolyl, benzofuranyl, J-thienyl, quinolyl, isoquinolyl, fluorenyl, isodecyl, 1H-isoindolyl, a & azobenz [1,4]-u 17 well, Ben [1,3] Di-indenyl, tetrahydron-n-butyl or di-oxypiperidinyl.), or a substituted heterocyclic group: having a halogen atom, a C1_C4 alkyl group, a hydrazine, a substituted C1 - C4, C2 - C4 alkenyl, C2 - C4, 4, alkynyl, C2 - C4 haloalkynyl, C3 - C8 cycloalkyl, C3 - c8 halocycloalkane C3 alkoxy, C1 - C3 halogenated oxy group, C1-C3 sulphur-based group, Cl-di-thio group, Cl-C3 alkyl sulfinyl group, Cl-C3 haloalkyl sulfinyl group, 3-alkyl sulphate, C1-C3 halogen Pyrite phthalic acid group, C1 - C4 amine group, di-C4 amine group, cyano group, schiffyl group, thio-c4 group, C1 - C4 14 200836629 halogen group, Cl-* carbonyl, 0 -C4 group, C1-C4 halogen-siloxy group, C-C4 alkoxy group, C1-C4 wire, C1-C4-burning amine group, C1-C4 halogen-burning carboxamide group, pentafluorosulfanyloxy group, aromatic The sulfonyloxyheterocyclic group means a substituent on the gamma or a different gamma X (here: =;:: group; basal dioxin, ,;,,, oxazolyl, fluorene 2: 4: carbaziryl, oxadiazolyl, thiazolyl, isothiazolidine, decyl, tris-s, s, s, ί base, 1H-extra-mail base, 2,3-bi-quinone-benzo-only γ γ ΐ ΐ: ] two-salt, tetrahydro-bromo or dihydro-pyranyl) ' C1-C4 a C3 ίΐ J } cf cff^' C1-C4^' embossed oysters & ΓΜ 3 said melon, C1 - C3 South sulphur, Cl - C3 alkane: C3 kiwi yellow wine, C1 - C3 slate yellow Base, C1 C2-C6 = case of bauxite or murine base, excluding Υδ is C1-C4 halogen wire base, 戍ci king perfluoro sulfonium thio group, ci-c6 perfluoromethanesulfinyl group or Cl-C6 The case of perfluoroalkylsulfonyl. )}. The insecticidal composition of the formula [1], wherein the compound represented by the formula (1) is a carbon atom, a nitrogen atom or an oxidized nitrogen atom, A2, A3, and A4; 'R1, R2 independently of each other represent a hydrogen atom or a C1-C4 alkyl group.

Gi, independently of each other, represents an oxygen atom or a sulfur atom. The soil '$ is ^^ does not indicate a hydrogen atom, a halogen atom or a triple η which is not an integer of 4;

Qi represents a phenyl group, a substituted phenyl group: having a halogen atom, a C-C4 Imi πγ^ι C2-C4 alkenyl group, a C2-C4 haloalkenyl group, a C2 C1 - C3 H C3 ^ C8 cycloalkyl group, C3 — C8 i cycloalkyl, d C3 calcined base, C1-C3 halooxy, α-c3 sulfur-burning, α-o-tooth 15 200836629 alkylthio, Cl-C3 alkylsulfinyl, ci- C3 haloalkylsulfinyl, Cl-C3 alkyl fluorenyl, C1-C3 haloalkylsulfonyl, C1-C4 alkylamino, di-C1-C4 alkylamino, cyano, nitro, hydroxy, ci a C4 alkylcarbonyl group, a C1-C4 haloalkylcarbonyl group, a C1-C4 alkoxycarbonyl group, a C1-C4 haloalkylcarbonyloxy group, a C1-a4 alkoxycarbonyl group, a C1-C4 iS azide base, a C-C4 burn Amino, Cl—C4 ii, aminyl, Cl—C4, fluorenyl fluorenyloxy, C1—C4 i|alkyl decyloxy, aryloxy, pentafluorosulfanyl or phenyl One or more substituents which are the same or different, and a miscellaneous jade group (in this case, he represents a group of heptyl groups, a ruthenium group 12, an N-oxide U-bite group, a thiol group, a sigma group, a bite Base, porphinyl, sulfhydryl, iso-tr-salt, tr-numbered , fluorenyl, stilbene, bismuth XI, π to T7, succinyl, trisyl, "bisazolyl, tetrazolyl, 2,3-dihydro-benzo [1,4] Diterpenyl, benzo[[2], tetrahydroindenyl or dihydro-carbyl.) or, substituted heterocyclic: having a selected atom, C1-C4 Alkyl, C1 - C4 haloalkyl, substituted C1 - C4 alkyl, C2 - C4, C2 - C4 halo, C2 - C4 alkynyl, C2 - C4 haloalky, C3 - C8 , C 3 -C 8 halocycloalkyl, C 1 -C 3 alkoxy, C 1 -C 3 haloalkoxy, Cl-C 3 alkylthio, C 1 -C 3 haloalkylthio, C 1 -C 3 alkylsulfinyl, Cl—C173 haloalkyl sulfinyl group, Cl—C3 alkyl decyl fluorenyl group, C1—C3 halogenated fluorenyl fluorenyl group, C1—C4 acryl group, di C1—C4 acryl group, cyano group, nitro group, thiol group, Cl—C4, a C1, a C4, a halogenated carbonyl group, a C1—C4 caloxy group, a C1-C4 halogenated oxy group, a ci-C4 aerobic acid group, a C1-C4 halogen-burned oxycarbonyl group, a C1-C4 group. Burning carbonylamine group, ci-C4 halogen-burning carbonylamine group, C1-C4 sulphur base xantheneoxy group, Cl-C4 halogen group One or more substituents which may be the same or different among the yellow oxy, aryl xanthine, pentafluorosulfoxy or phenyl groups (herein, the heterocyclic group represents a ratio of 17 wells, a bite base, N - cerium oxide base, u-density base, oxime, furyl, thienyl, carbazolyl, isoxazolyl, indenyl, thioxyl, isovalent wahyl, succinyl, ϋ 洛 洛 洛 洛 洛 洛 洛 洛 洛 洛 洛 洛 洛 洛 洛 洛 洛 洛 洛 洛 洛 洛 洛 洛 洛 洛 洛 洛 洛 洛 洛 洛 洛 洛 洛 洛 洛 洛 洛 洛 洛 洛 洛 洛 洛 洛 洛 洛 洛 洛Present π-based, tetrahydro-branched or dihydro-branched. ); 16 200836629 Q2 is of general formula (2)

(2) -C6 phase ^ or different, indicating M atom, C1-C6 group, α group, group, C1-C6 halogen alkoxy group, Cl-C6 sulphur sulfonyl group, α-76 alkyl group, C1~~C6 ialkyl subunit; sulphate, Cl-C6 sulphonyl, cyano or arginyl U may be the same or different 'representing hydrogen atom, self atom or C1—a C6 Perfluorodecyloxy, pentafluorosulfonyl, atom, ruthenium atom, = from hydrogen atom, via group, chlorine atom, >1 with i =. Base = iron C1-C6 halogen drive with the same or non-atomic sulfur-based group: selected from a hydrogen atom, a hydrogen group, a chlorine atom, a ruthenium, an atom, a Cl-C6 alkoxy group or a C1- C6 lir 颜其夕 is replaced by Γ / odor with more than one substituent, m is the same or not ^ Cl-C6 _ 垸 亚 亚 醯 醯 : : :: selected from the child, / stinky atom, hard atom, C1 - C6 stun, two', working group, gas or the same or different one or more substituents taken from the C6 sharp oxygen phase or substituted C1 - C6 haloalkylsulfonyl group: sister white bromine atom , an iodine atom, a C1-C6 alkyl group, an anthracene atom, a hydroxyl group, a chlorine atom, a C6 ugly oxy group which is the same as one or more substituents, or an insecticidal composition of the formula (i) 3i such as [1] A compound represented by the formula (1), wherein A! represents a carbon atom, a nitrogen atom or an oxidized nitrogen atom; 17 200836629 A2, a3, a4 represent a carbon atom; >, I independently represent a hydrogen atom or ci —C4 alkyl; 1 & independently represent an oxygen atom or a sulfur atom; XJ is the same minus, meaning a hydrogen atom, ', prime η represents an integer from 〇 to 4;

Qi represents a phenyl group, which has a group selected from a 4-atom atom, a C1-C4 alkyl group, a C1-C4 halogen group, a C2~C4 alkenyl group, a C2-C4 south alkenyl group, and a C2 C1-C3^ oxygen group. X C1, group, C3 - C8 ring filament, C3 - C8 4 cycloalkyl, 2: _ group, C1-C3 sulphur group, d-C3 tooth ^ cl- a C4 alkane 脍 AI haloalkyl stone Kfe group, Cl—C4 alkylamino group, di-C1 group, a-group, silk, C1-C4 silk group, C1-C4 letter

Cl—C4 iif, ci — c 4 halocarbonyloxy, C 1—C 4 alkoxycarbonyl,

Cl—C4—C4 alkylcarbonylamino group, C1-C4 from alkanoamine, pentafluorodivertinane f: xantheneoxy, arylsulfonyloxy, or the same or different substituents in Aizhong, brigade k , a heterocyclic group of ί ϋ 四 四 四 四 四 四 四 四 四 四 四 四 四 四 四 四 四 四 四 四 四 四 四 四 四 四 四 四 四 四 四 四 四 四 四 四 四 四 四 四 四 四 四 四 四 四 四 四塞二°坐基,转基,♦坐基,三嗤基, 巫其土 = 2,3'' dihydro-benzo[1.,4] two slogan, benzo[13] Base, tetramethylene or dihydro (tetra). L , J ^ or, (iv) substituted heterobasic group: having a halogen atom, a Cl - C4 alkyl group, a C1 - C4 halogen C1 - C4 alkyl group, a C2 - C4 dilute group, a C2 - C4 haloalkenyl group, 7 fast radical, haloalkynyl, C3 - C8 cycloalkyl, C3 - C8 li ring burning, * burning gas base, C1 - C3 halogen burning dairy base, C1 - C3 sulfur-burning base, C1 - C3 halogen burning stone melon尸~C3 烧基亚石石基, C1—alkyl sulphonate, C1-C3 stellite f si, α-ahalo, a_C4 arunyl, ss. Amine, cyano, nitro, hydroxy, ci-C4 alkylcarbonyl, C1-C4 halogen-burning gas group, Cl-C4 decyloxy group, ci-C4 halogen-burning oxo group, C1-C4 oxynol , C1 - C4 halogenated calorific acid base, C1 - C4 burned Wei amine group, C1 - C4 halogenated amino group, C1 - C4 alkyl group, oxime, C1 - C4 haloalkyl group, aryl sulfonate One or more substituents which are the same or different among the decyloxy group, the pentafluorosulfoxy group or the phenyl group (herein, the heterocyclic group represents a oxime group, a σ ratio bite group, an N-oxidation 12 ratio bite group, an eosinophilic group) Base, tower τι well base, σ 喃 基 ϋ, ϋ 吩 基 , , , , , , , , , , , , , , , , , , , , , , Tr-based, isoxazolyl, succinyl, pyrrolyl, imidaz, triazolyl, indole, tetrazolyl, 2,3-dihydro-benzo[1,4] The current well, benzo[1,3] octagonal, tetradecyl succinyl or dihydro bromo.); Q2 is of formula (2)

(In the formula, 'Y〗 is not C1 ~ C4 burning green base, C1 - C4 halogen burning base, C1 - C4 burning carbonyloxy, C1-C4 halocarbonyloxy, C1 - C4 alkoxycarbonyl, C1 - C4 Haloalkyloxycarbonyl, Cl-C4 alkylcarbonylamino, C1-C4 haloalkylcarbonyl, ci-C4 alkylsulfonyloxy, Cl-C4 haloalkylsulfonyloxy, substituted C1-C4 alkyl: Selected from a halogen atom, a C1-C3 alkoxy group, a C1-C3 haloalkoxy group, a C1-C3 alkylthio group, a C1_C3 haloalkylthio group, a C1_C3 alkylsulfinyl group, a Cl-C3 halogen alkyl group醢 、, Cl — C 3 烧 醢 ' ' ' C1 — C3 垸 垸 醯 醯 醯 、 、 、 、 、 C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C , Cl—C4 halogenated alkyl, C1-C4, alkoxy, C1-C4 halocarbonyloxy, C1-C4 alkoxycarbonyl, C1-C4 haloalkyl, C1-C4 alkylcarbonyl, Cl— The same or different among C4 haloalkylcarbonylamino, ci-C4 alkylsulfonic acid, C1~C4 haloalkylsulfonyloxy, arylsulfonyloxy, pentafluorosulfanyl or alkyldecylalkyl One or more substituents are substituted; γ5 represents a 4-atom atom, a C1-C6 alkyl group, and a C1- C6 haloalkyl, C1-C6 19 200836629 S oxygen* alkoxy, C1-C6 sulphur-based, ci-C6*sulfuryl, «, a-C6 peach sulfonate, cyano or exact; C6 alkane The base stone 戸 ' Y2, Y4 may be the same or different, meaning hydrogen atom, halogen atom, Cl_C6 P 2 3 table 2 C1 - C4 halogen alkoxy group, C2 - C6 full I wire, total gas; C1-C6 ^ 弗 UT 丞C6 all-decane rolling base, pentafluorosulfanyl group, s.; taking t1 - C6 tooth alkoxy: selected from a hydrogen atom, a trans group, a chlorine atom, a catalyzed atom, a ruthenium atom, a Cl-C6 alkoxy group or Cl—C6 i alkane gas, which is substituted with one or more substituents, the same or not α «' ^ from the red group, substituted with more than one substituent ^ 6 s 垸 oxy The same or a nonionic, pyrenic acid group: substituted by a hydrogen atom, a hydrazine group, a (d) or more than one substituent substituted by d-C6 from the filament group or substituted C1- C6 haloalkylsulfonyl group · swayed by atomic atoms, filled with atoms, c! — C6, which is replaced by a secret atom, a sulfhydryl atom, a chlorine atom, and more than one substituent. An insecticidal composition which is the same in the oxy group or [4] as in [1]苴$ General formula, A] represents a carbon atom, a nitrogen atom, a compound, a ruthenium, a ruthenium 3, a 4 represents a carbon atom; a t-emulsified mouse atom, 2, > independently represents a hydrogen atom or c]-ci % Independent of each other, the oxygen atom or sulfur atom 'X may be the same or different, meaning hydrogenogen', I-11 represents an integer from 0 to 4, ', dentate atom or trifluoro-indenyl; Q! represents phenyl, 20 200836629 •, substituted by phenyl. Selected from halogen atom, Cl-C4 alkyl, Cl-C4 halogenated group, ^-alkyl group, C2-Wene, C2-C4 _ group, C2 C4 From block base, C3~C8 cycloalkyl, C3-C8 halocycloalkyl, - basin, = oxo, C^C3 haloalkoxy, Cl-C3 alkylthio, Cl-C3 halo' Cl—C3 alkyl sulfinyl, C1-C3 haloalkyl fluorenyl, ci — C3 alkyl, acid group: C1^C3 halogenated fluorenylxanthyl group, C1_C4 acryl group, di C1 • n amine, ,, base, deterministic, subtractive, C1-C4 calcined, ci-c4 tooth succinyloxy, C1-C4 self-problem oxy, C1-C4-recording, C1_C4, C1_C4, amino group, C1- C4 halogen burned amine base, • ^ gas base, C1 - C4 _ burnt stone xanthine Aromatic fluorescein, _ or one or more substituents are substituted, and the sulphonyl group of Li is represented by a thiol group.塞 基 基, 啊 基, 解丝二唾土, 土土土,, thiazolyl, thiadiazolyl, pyrrolyl, imidazolyl, triazolam, ^四巧ί, 2,3 - dihydro- Benzo[1,4]diyl, benzo-, 3" oxazolyl, tetradecyl-pyranyl or dihydropyranyl. ), or, may take ίίΪί cf from a crypto atom, C1-C4 alkyl, C1-C4 _ ^C4=HC4/yl, & C4 alkenyl, C2-C4 haloalkenyl, A-ct alkoxy oxime block, C3_C8 cycloalkyl, C3—C8i naphthenic C3 > Cl "c3 C'7? ^ 'C1~ a -C4 alkylamino, cyano, nitro-diyl ; 01 -C4 alkylamino, di C4Fhr, carboxy, C1_C4 halosiloxy, C1-C4 calcination = base, a-C4 halogen burnt group, C1-C4 burnt carbonyl group, C1-c = ί , oxy, C1-C4 halosulfonyloxy, "nonyl fluorenyl thiophene, rectifying, iso-based D-slit, ♦ sitting 21 200836629, isothiazolyl, thiadiazolyl, pyrrolyl, Imidazolyl, triazolyl, pyrazolyl, tetradecyl, 2,3-dihydro-benzo[1,4]dijin, benzo[cutinoxazolyl, tetrahydropyranyl or hydrazine Piperidyl); Q2 is of formula (2)

(2) In the formula i, Yl represents C1-C6 alkoxy, Cl-C6 halo alkoxy, α-C6 ίί stone mi ^thio, ci-c6 alkyl amide, ci-π halogen burning Base ore sulfhydryl or C1-C6 self-burning basal yellow wine base; US 5 table, -C1-C6 alkyl, C1-C6 halogen alkyl, C1-C6 alkoxy: C6 alkane ίίί, C1 - C6 Sulfur, C1 - C6 Yaothio, Cl, C1:C6 ij^, *C1:C6 dentate tartaric acid, C1-C6 alkylsulfonic acid I C6 haloalkylsulfonyl, cyano Or nitro; ^ C1-C6 In the formula (1), the group of [] is a compound represented by the formula (1), and the formula 5 represents a sub, a nitrogen atom or an oxidized nitrogen atom. 2 A3, A4 represents a carbon atom; ',, ^, and Han 2 are independent of each other to represent a gas atom or C1 ^

Gl, G2 independently of each other represent an oxygen 4 alkyl group; x may be the same or different, if or a sulfur atom; n represents an integer of 0 to 4, 7 atom, _ atom or trifluoromethyl group;

Qi means stupid base, ‘substituting stupid base: α- selected from self-primary and Zhao-substituted. 4 alkylene II; sub, C1-C4 alkyl, C1-C4 halogenated C1-C4 alkynyl, C2-C4 haloacetylene, Γ1 C4 alkenyl, C2-C4 haloalkenyl, C2 l-C3 alkoxy , a-cr4 垸 ^ 烧, C3—C8 halocycloalkyl, fluorenyl, Cl—C3 alkylthio, C1-C3 halogen 22 200836629 alkylthio, Cl—C3 alkylsulfinyl, Cl — C3 haloalkyl sulfhydryl, ci-C3 alkyl fluorenyl, ci-*C3 halosulfonyl, C1-C4 acryl, di-C1-C4 acryl, cyano, nitro, Hydroxy, ci-C4 calcined carbonyl, ci-C4 haloalkyl, C1-C4 alkoxycarbonyl, C1-C4 halocarbonyloxy, C1-C4 alkoxycarbonyl, C1-C4-alkoxycarbonyl, C1- C4 alkylcarbonylamino, C1_C4 haloalkylcarbonyl, ^C1 -C4 alkyl decyloxy, C1 - C4 halogenated fluorenyl fluorenyloxy, aryl decyloxy, pentafluorosulfanyl or phenyl One or more substituents which may be the same or different, a heterocyclic group (herein, a heterocyclic group means a ruthenium base, a tj thiol group, an N-oxygen η ratio octyl group, a pyrimidinyl group, a hydrazine group, a furyl group, a thiophene group Base, carbazolyl, isoxazolyl, oxadiazole, thiazolyl, isothiazolyl, thiadipine Azyl, pyrrolyl, imidazolyl, triazolyl, °, oxazolyl, tetrazolyl, 2,3-dihydro-benzo[1,4]dioxinyl, benzo[丨,3]dioxin Zinyl, tetrahydropyranyl or dihydropyranyl.), or, substituted heterocyclic: optionally selected from a halogen atom, a C—C4 alkyl group, a C1—C4 halogen group, a substituted C1—C4 Alkyl, C2-C4 alkenyl, C2-C4 haloalkenyl, C2-C4 alkynyl, C2-C4 haloalkynyl, C3-C8 cycloalkyl, C3-C8 halocycloalkyl, Cl-C3 alkoxy , C1 - C3 haloalkoxy, C1_C3 alkylthio, α - C3 halogen thiol, Cl - C3 alkyl sulfinyl, Cl - C3 haloalkyl sulfinyl, 10 C1 ~ C3 alkyl Sulfhydryl, C1 - C3 haloalkyl, decyl, C1 - C4 alkylamino, di C1 - C4 acryl, cyano, schiffyl, thiol, (^^64), 〇:1 - 〇4 Halocarbonyl, C1 - C4 alkoxycarbonyl, C1 - C4 halocarbonyloxy, C1 - C4 alkoxycarbyl, C1 - C4 haloalkoxycarbonyl, C1 - C4 alkylcarbonylamine, C1 - C4 haloalkylamine , C1 -C4 alkyl decyloxy, C1 -C4 haloalkylsulfonyloxy, arylsulfonyloxy, pentafluorosulfanyl The same or different one or more substituents in the phenyl group (the heterocyclic group here means pyridinyl, pyridyl, N-pyridylpyridyl, pyrimidinyl, morphine, furyl, thienyl, carbazolyl) , isoxazolyl, oxadiazolyl, thiazolyl, oxime, fluorenyl, hydrazine T7, imidazolyl, tridecyl.嗤基基's tetracycline, 2,3-dihydro-benzo[i,4]dioxin, benzo[1,3]dioxazolyl, tetrahydropentanyl or dihydropiperidyl . ); 23 200836629 Q2 is of general formula (4)

Ra(4) Y4 Rc1

(The Vi I group and Cl^ may be the same or different, and represent a halogen atom, a Cl—〇6 alkane Shoumei 6 self-burning group, a C1—C6 alkoxy group, a C1—C6 _ alkoxy group, a C1 — a halogen 1~ C6 _ sulphur-burning group, C1-C6-alkyl sulfinyl sulfonyl group, C1-C6 cyano sulphonyl group, Cl-C6 sulphonyl fluorenyl group, C1-C6 halogenated sulphate sulphate group, alkyl group Y2, Y4 may be the same or different, indicating A hydrogen atom, a halogen atom, or a Cl-€6 Ra represents a south atom or a hydroxyl group; an alkyl group represents a hydrogen atom, an atom, or an atom or a Ci-a tooth atom or a ^^^ having one or more hydrogen atoms, minus , a chlorine atom, a & composition, wherein the formula (1) is a pesticidal composition for seed or harvest, and is characterized by containing one or more compounds of the compound represented by the formula (). As = (X)n 2

N, R- G2 (5) Nitrogen atom or oxidized > {wherein, Αρ A2, A3, A4 each represent a carbon atom 虱 atom, Z represents an isp^SC^Q〗 or - called anti-can; 24 200836629 ? R2 independently of each other means hydrogenogen*, C1-C4 filament G2 is a non-oxygen atom or a sulfur atom; an alkyl group, trifluoromethyl is the same or different 'Table 7 ^ hydrogen atom, halogen atom, C1-C3 alkyl or η Indicates an integer from 〇 to 4;

Qi means phenyl,

Substituted phenyl: optionally derived from a self atom, a C1_C4 alkyl group, a d group, a substituted C1-C4 alkyl group, a C2-C4 alkenyl group, a C2-C4 functional group L=block group, a -C4 alkynyl group , C3 __ C8 cyclofilament, C3 - C8 _ ring ^ base, 1 ^ 3 alkoxy, Cl-C3 functional alkoxy, C1_C3 decyl, a_C3 halocarbazide, Cl - C3 alkyl sulfin Base, C1_C3 - alkyl sulphonate, α - C3 sulphate, C1 - C3 _ sulphur sulphate, C1 - C4 acryl, bis: C4 alkylamino, cyano, nitro, hydroxy , C1—C4 alkylcarbonyl, ci—c4 tooth carbonyl, Cl—C4 alkylcarbonyloxy, ci—C4 halogen carbonyloxy, C1-C4 alkoxy, C1-C4 halooxycarbonyl, C1- C4 alkylcarbonylamino, C1_C4-alkylcarbonylamine, C1 cadaverine C4 alkyl sulfonate, ci-c4 halosulfonyloxy, aryl sulfoxide, pentafluorosulfanyl, amine or benzene One or more substituents which are the same or different in the group, p a ring group (here, a carbocyclic group represents a naphthyl group, a tetrahydronaphthyl group, a C3-C8 ring 1 alkyl group, a dihydroindenyl group, a burial group, 9 ~Sideoxydiyl, adamantyl or ruthenium.), soil-substituted carbocyclic group · selected from halogen Atom, C1-C4 alkyl, Cl-C4 haloalkyl, substituted C1-C4 alkyl, C2-C4 alkenyl, C2-C4 haloalkenyl, C2 C4 fast radical, C2-C4 haloalkynyl, C3 —C8 cycloalkyl, C 3 —C 8 halocycloalkyl, C 1 —C 3 alkoxy, C 1 —C 3 haloalkoxy, C 1—C 3 alkylthio, C 1 —C 3 haloalkylthio, Cl —C 3 alkyl Sulfonyl, Cl-C3 haloalkylsulfinyl, Cl C3 alkyl sulphide S& base, C1 - C3 halogenated sulphur base, C1-C4 arunyl, -Cl-C4 alkylamine, cyanide Base, nitro, hydroxy, C1-C4 alkylcarbonyl, C1-C4 halocarbonyl, Cl-C4 alkylcarbonyloxy, Cl-C4 halocarbonyloxy, Cl~C4 alkoxycarbonyl, C1-C4 haloalkoxy Carbonyl group, C1-C4 alkylcarbonylamino group, C1-C4 haloalkyl slow amine group, Cl-C4 alkylsulfonyloxy group, C1-C4 haloalkylsulfonyloxy group, aromatic continuous brewing oxygen 25 200836629 pentafluoro, alkane One or more substituents which are the same or different among the phenyl groups or the phenyl groups (here, the ring gas represents a naphthyl group, a tetrahydronaphthyl group, a C3-C8 cycloalkyl group, a dihydroindenyl group, a aryl group, and a 9-side oxygen group).第基基, 金刚烧基或降福基.), 〜表环基(在此Cyclic group means pyridyl, pyridyl, oxalyldinyl, ♦ group, keyl, fluorenyl, quinone, argyl, iso, m, sylylene, oxazolyl, isothiazolyl, thiazepine Azyl, pyrrolyl, imidazolyl, triazolyl, oxime, tetrasal, benzoxanthene, benzoxanthyl, benzoxanyl, ▲ porphinyl, face group, heteronym ,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, Cl r? 2: base, C3 - (tetra) alkyl, C3-C8 _ alkaloid furnace, base, C1 - C3 * alkoxy, C1-C3 sulfur-burning, ci-C1, 丝丝亚基基, C1-C3 from A. sylvestris, C1-C4^4T^, C1-C3 filegyl, C1-C4 acryl, di-C1 C4 alkylamino, cyano, nitro, one ^^^ Silk, C1—C4, Shanghai, m π, base, 鲈, Γ1—ΓΜ上·, 虱, C, C, 虱, 虱, C, C, C, C, C, C, C, Cl, Cl, Burning amine-based, five-gas furnace; C1-C4 halogen-silica xanthine, arsenic acid oxygen, the same or different ones in the base or the base Daiji (in the United States ui table does not call the base, D than bite base, n-oxidation ° bite base) dense bite base, do well base, 吱 基 base, 嗟 基 、, 唆 base, well base, benzo嗟 基 , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , Base, tetrahydro (tetra) or dinitrogen 26 200836629 q2 is phenyl; substituted phenyl · selected from halogen atom, Cl - C4 alkyl, Cl - C4 haloalkyl, substituted Cl - C4 alkyl, C2 —C 4 alkenyl, C 2 —C 4 haloalkenyl, C 2 —C 4 . alkynyl, C 2 —C 4 alkynyl, C 3 —C 8 cycloalkyl, C 3 —C 8 halocycloalkyl, C 1 —C 3 alkoxy, C 1 — C3 haloalkoxy, C1-C3 alkylthio, C1-C3 haloalkylthio, C1, an alkyl, a C1, a C3, a halogen, a sulfhydryl, a C1 - C3, a sulphate, a C1 a C3 halogenated sulfonic acid group, ci-*C4 acrylamine group, diCl-C4 alkylamino group, cyano group, nitro group, hydroxyl group, C1-C4 alkylcarbonyl group, ci-C4 i-alkylcarbonyl group, Cl-C4L oxygen Base, C1 - C4 halogenated oxy group, C1-C4 aerobic group, C1 φ - C4 halogenated oxycarbonyl, C1 - C4 Alkylcarbonylamino, C1 -C4 i|alkylcarbonylamino, C1 -C4 alkylsulfonyloxy, C1_C4-alkylsulfonyloxy, arylsulfonyloxy, pentafluorosulfanyl or phenyl One or more substituents which may be the same or different, a carbocyclic group (wherein the carbocyclic group represents a naphthyl group, a tetrahydronaphthyl group, a C3-C8 cycloalkyl group, a dihydroindenyl group, a aryl group, a 9-side oxime group) Base, adamantyl or ruthenium. Substituted carbocyclic group: selected from a halogen atom, a C1-C4 alkyl group, a C1-C4 halogen-based group, a substituted Cl-C4 alkyl group, a C2-C4 alkenyl group, a C2-C4 dentate group, C2 —C 4 alkynyl, C 2 -C 4 haloalkynyl, C 3 -C 8 cycloalkyl, C 3 —C 8 halocycloalkyl, C 1 -C 3 alkoxy, C 1 —C 3 halo alkoxy, C 1 —C 3 sulphur, ci -C3 halogenated sulfur group, C1-C3 alkyl sulfinyl group, C1 - C3 haloalkyl sulfinyl group, C1 - C3 alkyl fluorenyl group, Cl - C3 haloalkyl group, ci - C4 alkane Amine group, di C1 - C3 acrylamine group, cyano group, nitro group, thiol group, ci-C4 group, ci-C4 halogen carbonyl group, C1-C4 carbonyloxy group, C1-C4 halogen carbonyl oxide Base, ci~c4 calcined weigen, ci-C4 i alkoxycarbonyl, C1_C4 alkylcarbonylamine, C1-C4 succinylamine, C1:C4 alkylsulfonyloxy, C1_C4 haloalkylsulfonyloxy The same or different oxime substituents in the aryloxy group, pentafluorosulfanyl group or phenyl group (wherein the carbocyclic group represents a naphthyl group, a tetrahydronaphthyl group, a C3-C8 cycloalkyl group, two Hydroquinone, 9-oxyl, adamantyl or ruthenium.), soil heterocyclic (here The ring group represents a oxime group, a thiol group, a ν-oxygen group, a pyridyl group, a pyridyl group, a furyl group, a thienyl group, a carbazolyl group, an isoxazolyl group, a thiol group, and a thiazole. Base, isothiazolyl, thiadiazolyl, pyrrolyl, imidazolyl, triazolyl, specific 1 group, tetrasyl, benzofluorenyl, benzoxanthene, benzofuranyl, benzo "Sepeno, porphyrin, isoquinolinyl, bromo, isodecyl, 1H-isoindole, 2,3~dihydro-benzo[I,4]二今井基,苯And [(3) oxazolyl, tetrahydropiperidinium or mononitrocarbamic acid.), substituted heterocyclic group: selected from halogen atom, C1-C4 alkyl group, C1-C4 south alkyl group, substituted Cl—C4 alkyl, C 2 —C 4 alkenyl, C 2 —C 4 haloalkenyl, C 2 C 4 alkynyl, C 2 —C 4 haloalkynyl, C 3 —C 8 cyclodyl, C 3 —C 8 South ring, C 1 —C 3 Oxy, C1 - C3 functional alkoxy, C1 - C3 sulphur, d · C3 halogen thiol, C1 - C3 alkyl sulfinyl, Cl - C3 haloalkyl sulphate, Cl - C3 Base 醯 、, ci — C3 iS alkyl base, C1 — C4 amine group, two C1~C 4 alkylamino, cyano, nitro, hydroxy, C1-C4 alkylcarbonyl, C1 - c4 halogenated thiol, Cl-C4 alkylcarbonyloxy, Cl-C4 halocarbonyloxy, Cl-C4 alkoxy , C1-C4 i alkoxycarbonyl, α-C4 alkylcarbonylamino, C1_C4 _alkylcarbonylamino, C1-C4 alkyl decyloxy, ci-C4 haloalkylsulfonyloxy, arylsulfonyloxy The same or different substituents among the groups, pentafluorosulfanyl groups or stupid groups (herein, the heterocyclic group means pyridinyl, pyridyl, N-oxaridinyl, pyrimidinyl, hydrazine, Furanyl, thienyl, oxazolyl, isoxazolyl, oxadiazolyl, thiazolidine, fluorenyl, fluorenyl, whipyl, tridecyl, η thiol, Tetrasinyl, stupid and thiazolyl, benzoxazolyl, benzofuranyl, benzothienyl, quinolyl, isoquinolinyl, fluorenyl, isodecyl, 1 Η-isodecyl, 2,3-dihydro-benzo[I,4]dipin, benzo[丨,3]dioxazolyl, tetrahydropyranyl or dihydropyranyl. , a Cl—C6 alkyl group, or a substituted C1-C6 alkyl group, selected from a halogen atom, a C1-C4 haloalkyl group, a C2-C4 alkenyl group, a C2-C4 i alkenyl group, a C2-C4 alkynyl group, C2-C4 haloalkynyl, C3: C8 cycloalkyl, C3 - C8 halocycloalkyl, Cl-C3 alkoxy, C1 - C3 haloalkoxy, C1-C3 alkylthio, C1 - C3 haloalkyl , C1 - C3 alkyl sulphate, C1 - C3 haloalkyl sulfinyl, C1 - C3 alkyl fluorenyl, C1 - C3 haloalkyl sulfonyl, C1 - C4 alkylamino, C1 —C4 alkylamino, cyano, nitro, hydroxy: 28 200836629 C1-C4 fluorenyl, C1-C4 haloalkyl, ci-c, oxy, C1-C4 oxime, α-c4, C1-C4 is a carbonylamine group, a C1-C4 halogen residue, a ruthenium group, and a Cl-C4^'Cl-C4 group having one or more substituents}. The same or none of the aphids in the murine alkyl group or the base is characterized in that the insecticidal composition of any of the items (1) to (7) is characterized by: contacting any one of the above (1) to m The method of plant seeds is mi 2 T1 soil treatment, soak treatment or powder coating treatment. , rice, sugar beet, wheat, barley, sunflower, potato, sweet potato, the seeds of the seeds of a hundred people, 'Taro, [12] as in the prevention of the above, mouth, to the root of the ball. Fresh noodles: gamma Ren ===== Sub-characteristics: It treats the former _~[7]::子子_ fumigation fumigation. In the earthen cloth, π bubble treatment, powder coating treatment or - item will be paste, medium treatment, fumigation fumigation or room injection. 〜包处理叔衣 依,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, [Common application method] (the best position for implementing the invention) Assign +, "Ca-Cb (a, b indicates that 1 or more means that the number of carbon atoms is 1 to 3, -J means positive (n〇nnaD f C4" means the number of broken atoms is 1 to 4", and "η" The second is the third (tertiaiy). The table is not the other one--, the "ceto atom" and the "base" are as follows. Atom, chlorine, bromine or hard atom. For example, /methyl, ethyl, yoke, isopropyl, propylene butyl, etc. 'e.g., n-butyl, t-butyl, isobutyl, alkyl", except for carbon atoms 1 to 4 The base of the house, "C1—C6 ^ ^ ^ ^ 2-^ . 3- C4 dentate alkyl, " _ ^ f base, for example: halogen atom, d - C4 haloalkynyl, C3sC8jm " dihalide - alkynyl, -C1 - C3 decyl, C3 - C8 halocycloalkyl, €1_3 alkoxy, alkyl sulfinyl, m = thio, alpha - sulfhydryl , ci—ο Cl-C3 kiln base, Ci-C3 lysine, base, nitro, C C4 _ group, two C1-C4 amine group, cyanide group, CltC4 from 4 burning C1 - C4 Halogen, Cl-C4 oxycarbonyl, C^C4 ==, Cl-C4 alkoxycarbonyl, Cl-C4 4 alkoxy, ci~C4 C4 S Tertamine, C1_C4 alkyl sulphate. Substituting C1~CM?^*yl-nonyloxy, arylsulfonyloxy, pentafluorosulfanyl or benzene C4 alkyl' has the same or different One or more 30 200836629 Substituents. Monochlorohalide sulfhydryl groups, for example, monofluoroindolyl, difluoroindolyl, tri-indolyl, 虱曱', y-methyl, dichloromethyl, mono Methyl, dimethyl methyl, trichloroethylene H2-ethyl, 2,2-difluoroethyl, 2,2,2-trifluoroethyl, 1 2 2 虱 ethyl, 2, 2 —dichloroethyl, 2,2,2-trichloroethyl, 淳-bromoethyl, 2,2-dibromoethyl, such as tribromoethyl, 2-iodoethyl, earth, 3 —Fluoro-n-propyl, 3-chloro-n-propyl, 3-bromo-p-propyl, 1 kg-propyl, 1,3-dichloro-2-propyl, l1,1-trifluoro- 2~propyl, _propylmei' soil, 2,2,3,3,3-pentafluoro-n-propyl, heptafluoro-isopropyl^not ir-propyl, pu-u, 2,3, 3,3-hexafluoro-2-propyl group, etc., a linear or branched chain of carbon atoms substituted by one or more halogen atoms, "C1-C4 s alkyl", except for "ci-c3 functional base" Outside = no Gas-n-butyl, non-n-butyl-n-butyl, non-n-butyl-2-butyl, etc. S number lif Λ 1 bis-*-atom substituted straight chain * branched chain carbon atom = 26,6 - trifluoro N-hexyl, nonafluoro-n-butyl, nonafluoro-2-butyl and the like tfH1. It seems to be a straight-woven or branched-chain carbon-based lining of a carbon-based alloy. For example, ethylene or alkene Propyl, 2-butenyl, 3-butadiene-chain wide-chain m-number 2~4 alkenyl '"c2-c4 4 alkenyl" butyl === upper arm, for example, block propyl, bubut block - 3-base, butyl block 2 to 4 bis, ^ in the linear or branched chain of carbon atoms with a reference to replace the fluorite chain: ^ silk", for example, the same different one or more halogens A block having a linear or branched bond carbon number of 2 to 4 in the middle of a wheat bond 31 200836629. a ring-like propyl group, a cyclobutyl group, a cyclopentyl group, a 2-methyl group number of 3 to 8 ^heptyl group, and the like, a carbon-based carbonyl group, a 2-chlorocyclohexane λ 8 'alkyl group, for example, 2, 2,3,3-tetrafluorocyclobutane atom substituted by ί / 状 · ^ f such as one or more different halogens "C1 ^ 5 structure reader number 3 ~ 8 cycloalkyl. Oxy Or a straight chain or: ^^ 'A & yldipropoxy, isopropoxy" In addition to "Cl-C3 ^ 数 1 3 decyloxy, "C1 - C4 burned or branched chain carbon number 1~4 For example, 2: a linear fluoromethoxy group such as a butoxy group, a 1,1 2:fluoroethylene C3*alkoxy group such as a tris-trisethoxy group, and a H-hexafluoro group. 2-propoxy, 2,2,2 oxy, 1 1 2 m? Fluorine-n-propoxy, U, 2,2-tetrafluoroethylene i iSi·: 麟麟氧鲜经_ 衫同Η The amphoteric acid having a branched chain of 1 to 3 carbon atoms, and "Cl-C4 ί 3 * alkoxy group", for example, 3, 2, 3, 3, 4, 4, 4 - 8 a linear or branched chain number of 1 to 4 of a fluorine- 2 -butoxy group substituted by the same or a 4-substituted atom, such as a methylthio group, an ethylthio group, N-propylthio, propyl propionate a sulfur-burning group having a carbon number of 1 to 3, or a C1 = 4 sulfur-burning group, in addition to a "C1 - C3 sulfur-burning group", for example, n-butylthio group and branched-chain vermiculite a sulfur- or s-methylthio group such as a sulphur-based group having a reverse atomic number of 1 to 4, such as a "C1_C6 sulfur-burning group", and a base column such as a 'n-pentylthio group, a positive one. A sulfur-based group or the like having a linear or branched chain shape and having 1 to 6 atomic numbers. "C1 - C3 haloalkylthio", for example, trifluoromethylthio, pentafluoroethylthio, thioethylthio, 2,2,2-trifluoroethylthio, heptafluoro-n-propylthio, seven Gas-isopropyl furnace base], 1,2,2-tetrafluoroethylthio group, ^2,3,3,3-hexafluoropropylthio group, etc. Or the number of branched chain carbon atoms Μ 32 200836629 The sulfur-burning group 'C1-C4 halogen thiol group except C1, for example, nonafluoro-n-butylthio group, nine gas _4 two ==3 base" f A sulphur-based group or the like which has the same or different enthalpy, 4,4 - 2 - y-n-chained carbon atoms having a carbon number of 1 to 4, "rj-xuan replaced by a chain or a branch. For example, there is a linear or branched branch of the above-mentioned fluoro-n-pentyl group: 6-based halogen (2). The original: it is not a stone-branched base, for example, 'methyl linoleic acid group, ethyl sub-surface ^ branch f Shouting the linear chain of the sulfinamide, the carcinogen, etc.: =: 3 to 3 alkyl sulfinate, "C1 - C6 alkyl sub-error i! D-f-sulfinyl" For example, 'n-butyl sulphite, scorpion scorpion, butyl sulphite, n-pentyl sulphate, and yin Meiya Shi-chain, branched-chain carbon number of Shu Siya ~ 6 of a sulfonic acid group. 1 μ soil straightening r ϋ 1^3 sister Kea ^ silk" such as 'trifluoromethyl sulfenyl, pentacene: ~, 2, 2, 2 - tri-glyethyl sulfinyl, heptafluoro - n-propyl fluorene fT di t-i propyl sulfhydryl, u, 2, 2 - tetrafluoroethyl hydrazine,, W - /, fluoropropyl sulfinyl, etc. Different i or more 1 take! ^5 chain or branched heterocarbon atom number 1~3 of the silk of the arginine base,, C1-C6 halogenated sulphate yttrium group "except rcl - ο 垸 sulfinyl sulfhydryl" by example ^, nine Fluorine-n-butyl sulphate sulphate, sulphate _f dibutyl sulphate, 4,4 4: fluoro-n-butyl ylidene, perfluoro-n-pentyl sulfhydryl, perfluorinated An alkyl sulfinyl group having 1 to 6 straight-chain branched carbon atoms substituted by the same or different one or more halogen atoms, such as Wu Yashi male &&>. or

Cl C3 base stone slab base", such as 'silk base yellow base, ethyl rhein base, n-propyl decyl group, isopropyl sulfonyl group, cyclopropyl stellite base, etc. An alkylsulfonyl group having 1 to 3 carbon atoms, a "C1 - C6 alkylsulfonyl group", and an "α-C3 alkyl sulphate base", for example, n-butyl stellite base, tert-butyl stone An alkylsulfonyl group having a linear or branched chain carbon number such as a meso-pentylsulfonyl group or a n-hexylsulfonyl group. ~ 33 200836629 #且二基续醯基" For example, trifluoromethyl-carbyl, pentafluoroacetic acid, fluorene-difluoroethylsulfonyl, heptafluoro-n-propylsulfonate, heptafluoroisopropyl Base group, U, 2,2-tetrafluoroethyl yl group, 〗 6 = sulphide group with a chain number of 1 to 3, "C1_C6 bismuth aryl ruthenium dihalo sulfonyl sulfonyl group In addition, there are, for example, nonafluoro-n-butyl sulfonate, 9,2-dibutyllithium, 4,4,4-trifluoro-n-butylstone, all-dipentylhetero, perfluoro-n-hexane Is the sulfonyl group and so on? A chain or branched chain of carbon atoms having a number of 1 to 6 is a fluorenyl group. From + aryl%, fe oxy" for example, phenylsulfonyloxy, p-toluene xanthine ~ cai, sulphur, oxygen, 2-naphthyloxy, fluorenyloxy, phenanthryloxy - Wind, base, surface oxygen, etc. The number of carbon atoms in the ring of 6~14 is the same. "C1 - C4 alkylamino group", for example, a mercaptoamine group, an ethylamino group, a n-propylamine group, a cyclopropylamino group, or the like, a linear or branched chain i-ring atom Alkylamino group of 1 to 4, "di-C1-C4 alkylamino group", for example, dimethylamino, diethyl silk, N-ethyl-N-methylamino group, etc. Alkyl group substituted with a chain or branched chain of 1 to 4 carbon atoms. "C1-C4 perfluoroalkyl group", for example, trifluoromethyl, pentafluoroethyl, heptafluoro-n-propyl I heptafluoroindole isopropyl, nonafluoro-n-butyl, nonafluoro-2-butyl, a linear or branched chain carbon precursor which is completely substituted by a fluorine atom such as nonafluoro-isobutyl group, "~C6 all-neutral", for example, pentafluoroethyl, sulphate, hexafluoro-n-butyl a linear or branched bond carbon number of 2,6, which is substituted by a fluorine atom, such as a hexafluoro-2-butyl group, a nonafluoro-isobutyl group, an undecafluoro-n-pentyl group, or a trifluoro-n-hexyl group. Burning base. ^ C1 — C6 perfluorosulfuryl group”, for example, trifluoromethylthio, pentafluoroethylthio, sulphate, heptafluoro-isopropylthio, nonafluoro-n-butylthio, nonafluoro a linear or branched chain carbon atom 全部~6 which is completely substituted by a fluorine atom, such as 2-butyryl hexafluoro-isobutylthio group, undecafluoro-n-pentylthio group, and tridecafluoro-n-hexylthio group. Alkylthio group. 34 200836629 ^ "C1-C6 perfluoroalkylsulfinyl", for example, trifluoromethanesulfinyl, pentafluoroethyl, sulfonyl, heptafluoro-n-propylsulfinyl, heptafluoro- Isopropyl sulfinyl, hexa-di-n-butylsulfinyl, nonafluoro-2-butylsulfinyl, nonafluoro-isobutyl-based, eleven-fluoro-n-pentyl A linear or branched chain carbon atom having a total number of 丨~6 alkyl groups, such as a fluorenyl group, a trifluoro-n-hexyl hydride group, or the like. Perfluoroalkylsulfonyl", for example, trifluoromethylsulfonyl, pentafluoroethanesulfonate heptafluoro-n-propylsulfonyl, heptafluoro-isopropylsulfonyl, nonafluoro-yl-based a non-chain-like or *branched group which is completely substituted by a fluorine atom, such as a nonafluoro-2-t-t-yl-heteroyl group, a nonafluoro-isobutylsulfonyl group, a decaenylpentylheteroyl group, or a thirteen-l-n-negative hetero group. A carbon-based 丨~6 filament hetero group. Burn a! For example, a mercapto-Wiki group, a trimethyl-Wilyl group, or an alkyl group is a linear or branched chain alkyl group. Or more, the compound sometimes has one configuration in its structural formula, and there are two insertions of af from the carbon-carbon double bond; the structure, the general formula (1) or the general formula (5) A compound comprising the substance and a mixture of such as any. All of the various geometric isomers or compounds represented by the formula (5) are preferably, for example, the following: the original shield 1 1 meaning 2 into 3, 8 4 car father Jia, Al is carbon atom, nitrogen; Sub-~ A2, A3, all carbon atoms = sub- or "formed nitrogen" are carbon atoms. Al, A2, A3, A4 are all hydrogen atoms, C1-C4 alkyl, more preferably chlorine, G , G2 ί chlorine atom, C1 - C4 alkyl group, more preferably hydrogen atom, formamidine, ethyl group.

X is preferably an oxygen atom. η is preferably. , 1 A : base, ethyl. More preferably, it is an oxygen atom, and halogen 2 is preferably ruthenium or 1 (10). The original L is a ruthenium atom or a gas atom. 35 200836629

Qi is preferably a phenyl group or a substituted phenyl group: optionally selected from a halogen atom, a C1-C4 alkyl group, a C1-C4 haloalkyl group, a C2-C4 alkenyl group, a C2-C4 haloalkenyl group, a C2-C4 alkynyl group. , C 2 —C 4 haloalkynyl, C 3 —€ 6 cycloalkyl, C 3 —C 6 i|cycloalkyl, Cl—C 3 alkoxy, ci—C 3 halo alkoxy, Cl—C 3 calcined base, ci—C 3 halo Calcined base, Cl-C3 alkylsulfinyl, C1-C3 haloalkylsulfinyl, C1-C3 alkylsulfonyl, cl-C3 haloalkylsulfonyl, Cl-C4 alkylamine, One or more of diCl—C 4 alkylamino group, cyano group, ruthyl group, hydroxyl group, Cl—C 4 alkylcarbonyl group, Cl—C 4 alkylcarbonyloxy group, 47C1-C4 alkoxycarbonyl group, and ethyl hydrazino group may be the same or different. Substituent,

Orbital base, or substituted σ than thiol: selected from _ atom, C1 - C4 alkyl, Cl - C4 halogen, C2 - C4 alkenyl, C2 - C4 halo, C2 - C4 alkyne , C 2 -C 4 haloalkynyl, C 3 -C 6 cycloalkyl, C 3 -C 6 halocycloalkyl, Cl -C 3 alkoxy, ci - C 3 haloalkoxy, Cl -C 3 alkylthio, ci -C3 i Alkylthio, C1-C3 alkylsulfinyl, C1-C3 haloalkylsulfinyl, C1-C3 alkylsulfonyl, fluorene-C3 halosulfonyl, Cl-C4 alkylamino , diCl—C 4 alkylamino group, cyano group, schlossyl group, thiol group, C1—C4 alkylene group, C1-C4 alkoxycarbonyl group, α—C 4 alkoxy group, and one or more of 'ethoxylated amino group. Or different substituents.

Qi is more preferably a phenyl group, and a substituted phenyl group is selected from a fluorine atom, a chlorine atom, a bromine atom, a broken atom, a methyl group, a fluorenyl group, a decyloxy group, a trifluoromethoxy group, a thiol group, and a W sulfonyl, methyl f fluoromethyl f, f fluorinyl sulfastyl, trifluoromethyl fluorenyl, methane-methyl, cyano, wall, W, may be the same or different substitution取 ΐ 原子 原子 原子 氯 氯 氯 氯 氯 原子 原子 原子 原子 原子 原子 原子 原子 原子 原子 原子 原子 原子 原子 原子 原子 原子 原子 原子 原子 原子 原子 原子 原子 原子 原子 原子 原子 原子 原子 原子 原子 原子 原子 原子 原子 原子 原子 原子, 酉 基 脸 其 - - - - - - - - - 2008 2008 2008 2008 2008 2008 2008 2008 2008 2008 2008 2008 2008 2008 2008 2008 2008 2008 2008 2008 2008 2008 2008 2008 2008 2008 2008 2008 2008 2008 2008

a pyridine group, wherein, in the case of the formula (2), (i) Yi, A are preferably the same or different, and represent a fluorine atom iodine atom, a thiol group, an ethyl group, a n-propyl group, an isopropyl group, and a positive group. Butyl sulfhydryl, sulfonium thiol, methyl sulphate, sulphur base, fluorenyl fluorenyl, trifluoromethyl sulphate, cyano; gas atom, bromine atom, I, 2-butyl, Trifluoromethane thiol, chloro i Y2, Y4 are preferably a hydrogen atom; Ο'/3, is a dithiol group, a pentafluorosulfuryl group, U, 2,3,3,3-hexafluoro Propyloxy, 2,2,2-difluoro-;!-trifluoromethylethoxy, 2trifluoromethoxy-tris, 1,1,2,2-difluoroethoxy Base, i, i, 2, 3, 3, 3 - hexapropylpropylthio, 2,2,2-fluoro-l-trifluoromethylethylthio, 2-trifluoromethoxy-1,1 , 2 - trifluoroethyl sulfide, 1,1,2,2-tetrafluoroethylthio, 1,1,2,3,3,3-hexafluoropropylsulfinyl, 2,2, 2 Trifluoro-1,3-trifluoromethylethylsulfinyl, 2-trifluoromethoxy-u, 2-trifluoroethyl sulfite gf, 1,1,2,2-tetrafluoro Keasulfonic acid, i, i, 2, 3, 3, 3 - hexafluoropropyl Sulfonyl, 2,2,2-trifluoro-l-trifluoromethylethylsulfonyl, 2trifluoromethoxy-1,1,2-trifluoroethylsulfonyl, U,2 , 2-tetrafluoroethylsulfonyl, one or (9) 1 is preferably, hydroxyindenyl, decyloxymethyl, methylthiomethyl, decylsulfinyl, methylsulfonyl , ethyl fluorenyl, trifluoroethyl fluorenyl, ethoxycarbonyl, carbonyloxy, trifluoroacetoxy, methoxycarbonyl, ethoxycarbonyl, ethionylamino, fluoroethenylamine, Methyl ferrocyanoxy, trifluoromethylsulfonyloxy, preferably fluorine atom, chlorine atom, bromine atom, iodine atom, sulfhydryl group, ethyl group, n-propyl group, isopropyl n-butyl hydrazine 2~ Butyl, trifluoromethyl, methylthio, methyl sulfite, methylsulfonyl, trifluoromethylthio, trifluoromethylsulfinyl, trifluoromethylphosphonium, cyano, Υ2, Υ4 is preferably a hydrogen atom; Υ3 is preferably pentafluoroethyl, heptafluoro-n-propyl, heptafluoro-isopropyl, nonafluoro-n-butyl: nonafluoro-2-butyl, nonafluoro Isobutyl, trifluoromethylthio, pentafluoroethylthio, heptaqi-n-propylthio, heptafluoro-isopropyl Base, nonafluoro-n-butylthio, nonafluoro37 200836629 2-butylthio, difluoromethylsulfinyl, pentafluoroethylsulfinyl, seven gas, one, one, seven -Isopropyl sulphate, nonafluoro-n-butyl sulphate, fluoro-2-butylindole, trifluoromethyl aryl, pentafluoroethyl, hexafluoro- N-propylsulfonyl, heptafluoro-isopropylsulfonyl, nonafluoro-n-butyl spectrum, nonafluoro-2-butylhetero, trifluoromethyl, u, 2, 3, 3, 3_ Hexapropoxy fluorene-tris-l-trifluoromethylethoxy, 2-trifluoromethoxy-u, 2-triethoxy, U, 2,2-tetrafluoroethoxy, U , 2,3,3,3—hexapropanylthio, 2,22—tris=-1-trifluoromethylsulfanyl, 2-trifluoromethoxy-u,2-trifluoroethylidene, 1"1 2 2,2 - 4,^thio, 1,1,2,3,3,3-hexafluoropropylsulfinyl, 2,2,2-difluoro-1,4-difluoromethyl Ethyl sulphate, 2,3-trifluoromethoxy-2,2-diethyl sulfinyl, 1,1,2,2-tetrafluoroethyl sulphate, u, 2, 3, 3^ _ = base hetero group, 2,2,2-trifluoro-i-three on methyl ethyl stellite base, [three / say base one 1 mountain 2 - Difluoroethylsulfonyl, m2-tetrafluoroethylsulfonyl, annual oxygen, pentafluoroethyl, trifluoromethylthio, pentafluoroacetamido, murine citrate, heptafluoroisopropylthio , difluoromethyl sulfhydryl, quinone, hexamethyl sulfite, seven gas isopropyl sulfite, sulphate, sulphate, sulphate, sulphate Base, heptafluoroisopropylsulfonic acid, a friend Y5j parent is a fluorine atom, a gas atom, a bromine atom, an iodine atom, a sulfhydryl group, an ethanediyloxy group, a pentafluoroethyl group, a trifluorosulfonylthio group, a Fluoroethylthio group, 1,

Isopropylthio, tri-Imethyl-Agaki, five-gas ethyl-branth, seven-W-decyl, heptafluoroisopropylsulfinyl, trifluoromethylsulfonyl, pentafluoro I streak Sulfhydryl, heptafluoropropylsulfonyl, heptafluoroisopropylsulfonyl; soils Y2, Y4 are preferably hydrogen atoms; 'Υ3 is a fluorine atom, a gas atom, a bromine atom, a broken atom · in the formula (4) In the case of ', pick the original m, the best S can be the same, is a atom, chlorine atom, desert atom, ,, di-mercapto, ethyl, n-propyl, isopropyl, n-butyl, 2-butyl It is a friend, a sulfhydryl group, a thiol group, a methyl sulfonyl group, a methyl ore, a methyl sulfenyl group, a trifluoromethyl group, a cyano group; a 4 thiol group, a difluoro group 38 200836629 Y2 I is preferably a hydrogen atom; a fluoromethym, Rb is a gas atom, Rc is a trifluoromethyl group, or Ra is a chloroform group, Rb is a mesogenic group, and Rc is a chlorodimethyl group. The compound of the above (1) is not a compound, for example, the following compound 1 to the compound of the old one. It is better to be user-friendly. Compound I, in the formula (1), fi represents a slave atom, a nitrogen atom or an oxidized nitrogen atom, Α2, Α3, Α4 represents a carbon atom;

Rl and R2 independently of each other represent a hydrogen atom or a Cl—C4 alkyl group.

Gi and 〇2 independently represent an oxygen atom or a sulfur atom; and 乂^ is the same or different, and represents a hydrogen atom η representing an integer from 0 to 4;

Qi is not unsubstituted, substituted phenyl··from halogen atom, ci—, a-C4 alkyl group, C2-di-C3 alkoxy group, C1-C3 tooth-burning Hf·, tooth ring , α thio, a-C3 alkyl sulfenyl, ci—C3 p 妒 n I n A :, C1~C3 haloalkyl sulfinyl, Cl—C3 stellite*, C1-C3 _ burnt fluorescens-based amphotery group, cyano group, succinyl group, · C1 m 4ci-C4 n] a na ϋ Α γμ ~ 上元 厌 Cl Cl Cl C4 halogen 爹 爹 base,

Cl C4 is said to be a secret group, a C1-C4 halogenated oxime oxime-C4 haloalkoxycarbonyl group, a C1~C4 alkane group, a decyl group, a C1 group to a 妒β-glycol group, a C1-C4 haloalkylcarbonyl group, The C1 -C4 alkyl fluorenyl group, the a_C4 succinyl group, the fluorinated sulphur sulphur or the phenyl group may be the same or different, and the hexyl group is the same as the H ring, and the ring group (wherein the heterocyclic group represents Μ) Base, nfct base ^ base, 嗟 基 base, iso 嗟 ^,, sulphate, diterpene, tetraki, 2, 3t 44t 1 base, material base, triterpene, one or two open f1, 4 Di- morphinyl, benzo[1,3]dioxene 39 200836629 σ, 1, tetrahydropyranyl or dihydro-u- yl.) or, substituted heterocyclyl: selected from its own C1-a silk, C1-—4 sister group, substituted Cl—C4 alkyl group, —C4 alkenyl group, C2-C4 haloalkenyl group, C2•—C4 alkynyl group, C2-C4 alkynyl group, C3—C8 Cycloalkyl, C3-C8 sec-cycloalkyl, • C1 - C3 alkoxy, C1 - C3 haloalkoxy, C1-C3 alkylthio, C1_C3 haloalkylthio, C1 - C3 alkyl sulfinyl , C1-C3 _alkyl sulfinylene, C1 - C3 sulphur base, C1 - C3 sulphur base yellow | blue base, ci - C4 amine group, two C l C4 alkylamino, cyano, nitro, hydroxy, C1_C4 alkylcarbonyl, C1_C4 haloalkyl 10 carbonyl, C1-C4 carbonyloxy, C1-C4 carbonyl carbonyl, C1-C4 oxycarbonyl, C1 a C4 haloalkoxycarbonyl group, a C1 to C4 alkylcarbonylamino group, a C1-C4 haloalkylcarbonylamino group, a C1-C4 alkyl fluorenyloxy group, a C1-C4-calcinyl fluorenyloxy group, a fluorite xanthine oxygen One or more substituents which may be the same or different in the group, pentafluorosulfanyl group or phenyl group (herein, heterocyclic group means pyridyl group, pyridyl group, N-oxidized pyridyl group, pyrimidinyl group, hydrazine group, furan group) Base, thiophene, thiophene, isoxazolyl, oxadiazolyl, fluorenyl, isodecyl, thiadiazolyl, u-indenyl, imidazolyl, triazolyl, thiazolyl , tetrazolyl, 2,3, dinitrogen, [I, 4], a well, benzo[1,3], diterpene, tetrahydron, or dihydrogen, sigma. Formula (2)

(wherein, γι and Υ5 may be the same or different, and represent a halogen atom, a C1-C6 alkane Cl C6 halogen group, a ci-C6 graft oxy group, a C1 - 'C6 halogen alkoxy group, a C1 group = a sulfur-burning group C1~C6 _ sulphur-burning group, C1-C6 alkyl sulfonyl, C1 - C6 haloalkyl sulfinyl, C1 - C6 alkyl fluorenyl, C1 - C6 haloalkyl fluorenyl, cyano or nitro; I, Y4 may be the same or different, and represent a hydrogen atom, a halogen atom or a C1-C6 200836629 Y3, which is not a gas, a pi r^r: . ^ a substituted mouse, a base, a five-gas sulfur, an atom, a moth atom, Cl-C6 calcined rf gas atom, thiol, chlorine atom, bromine substituted with more than one substituent 丨 or C1~C6 sister oxy group may be the same or non-atom, from hydrogen atom, hydroxyl group, chlorine atom, bromine With the same substituent taken by one or more substituents, the 4 C1-C6 oxy group of the soil may be the same or not, itr, or burned, from a hydrogen atom, a thiol group, a chloroform, or a different substituent. ^ or ci-c6 function in the alkoxy group may be phase or 'different one or more substituents taken H or C1-C6 sister's oxygen towel may be the same or (compound II) compound Π, in the formula (1) , ^ The carbon atom, the nitrogen atom or the oxidized nitrogen atom seven 2 A3, Α4 represents a carbon atom; and R2 independently of each other represents a hydrogen atom or a C1_C4 alkyl group; 1. > independently of each other represents an oxygen atom or a sulfur atom; The same or different, meaning that a hydrogen atom, a halogen atom or a trifluoromethyl group η represents an integer of 〇 to 4;

Qi represents a phenyl group, a substituted phenyl group: optionally selected from a halogen atom, a C1-C4 alkyl group, a C1-C4 haloalkyl group, a r?Cl-C4 alkyl group, a C2-C4 alkenyl group, a C2-C4 halogen group, C2—C4 二忘 j: C4 haloalkynyl, C3-C8 cycloalkyl, C3-C8 self-cycloalkyl, Cl decyl, oxy, C1-C3 sulphur-based, C1~C3 halogen-burning stone to妒3 alkaloids Y sulfhydryl, C1_C3 halogenated carbazite, C1 - C3, sulphate, Cl - 56C3 haloalkyl sulfonyl, C1 - C4 alkylamino, di cl_ 41 200836629 C4 amine , gas base, nitro, thiol, Cl - C4, several groups, ci - C4 halogen group, Cl - C4 burnt alkoxy, ci ~ C4 halogen burned oxy, Cl - C4 burned oxygen base, Cl-C4 haloalkoxycarbonyl, C1-C4 alkylcarbonylamine, C1-C4 halogenated amino group, Cl-C4 alkylsulfonyloxy, ci-C4 halogenated fluorenylxanthine, arsenite xanthine An oxy group, a pentafluorosulfanyl group or a phenyl group may have the same or different one or more substituents, and a heterocyclic group (herein a heterocyclic group means a pyridyl group, a pyridyl group, an oxypyridyl group, a pyrimidyl group, an anthracene group). Pentyl, furyl, thienyl, oxazolyl, isoxazolyl, anthracenyl, thiazolyl, Thiazolyl, thiadiazolyl, pyrrolyl, imidazolyl, triazolyl, pyrazolyl, tetrazolyl, 2,3-diphenylbenzo[1,4]dioxinyl, benzoquinazolyl , tetrahydropyranyl or dihydropyranyl.), ' or substituted miscellaneous springs are selected from the self-atomic atom... (4), "----------------- C1-C4 alkyl, C2- C4 alkenyl, C2-C4 from dilute base, C2 base = -C4 cleavage group, C3-(3) wei group, C3 - C8 halocycloalkyl group, = calcined base, Cl-C3 - alkoxy group, C1_C3 sulfur-burning Base, C1 - hydrazine, dif, Cl - C3 alkyl sulfinyl, α - C3 haloalkyl sulfinyl, α - , a - 57C3, sulfonyl, Cl - c4, base , alkyl 2, nitro, hydroxy, C1-C4 carbonyl, C1-C4 biscarbonyloxy, cl-C4 halocarbonyloxy, C1-C4 alkoxy t C1 - Γ4, C1 a C4-burning amine group, a C1-C4 halogen-burning carbonylamine i, a penta-propanyl group, a C1-C4 self-spinning oxo group, an arylsulfonyloxy group i-based table, or a substituent of more than one (here) Heterogeneous group, porphinyl group, present smirk base: oxygen, bite base, • base, tas, thiol, fluorenyl, i 4 = base Recording, Mian group, iso-dihydro sigh laugh i South Γΐ, group, benzo [ah two cut-yl, tetrahydro-thiopyran trip or Q2 is a group of the general formula (2) 42 (2) 21200836629

(wherein Υι denotes Cl—C4 alkylcarbonyl, C1-C4 halocarbonyl, C1~C4 caloxy, Cl—C4 chiral oxy, ci—C4 aerobic acid, Cl—C4 halogenated oxygen Carbonyl, C1 - C4 alkylcarbonylamino, C1 - C4 58 alkanocarbonylamino, C1-C4 alkyl fluorenyloxy, C1 - C4 cryptoyl fluorenyloxy, or substituted Cl-"C4 alkyl ··Selected from halogen atom, ci—C3 alkoxy, C1

—C 3 i alkoxy, C 1 —C 3 alkylthio, C 1 —C 3 —alkylthio, C 1 —C 3 alkyl sulfhydryl, C 1 —C 3 —alkyl sulfhydryl, ci —C 3 alkyl sulfonate Base, C1-C3 halosulfonylsulfonyl, C1-C4 butylamine, di-C1-C4 acrylamine, cyano, nitro, hydroxy, C1-C4 alkylcarbonyl, C1-C4 halocarbonyl, C1 C4 alkylcarbonyloxy, C1-C4 halogenated carbonyloxy, C1-C4 alkoxycarbonyl, C1-C4 haloalkyloxycarbonyl, C1-C4 succinyl, C1-C4d succinyl, C1-C4 Substituting one or more substituents which may be the same or different in the pyridylxanthine, C1-C4 haloalkyl group, arylsulfonyloxy group, pentafluorosulfanyl group or alkylalkylene group; Y5 represents Halogen atom, C1-C6 alkyl group, C1-C6 i alkyl group, C1_C6 alkoxy group, Cl-C6 halogen alkoxy group, a-C6 thiol group, α-C6 functional thio group, C1 - C6 alkyl group Sulfonic acid, C1-C6-alkyl sulfhydryl, C1-c fluorenyl, Cl-C6 haloalkylsulfonyl, cyano or nitro; alumina ', γ2, γ4 may be the same or different, Represents hydrogen atom, _ atom, ci_c6 courtyard; LZ· ϊ3 represents C1-C4 Haloalkoxy~-fluoroalkyl,: ?? C1; C6 slastic _ group, Cl-C6 hydroxyalkyl 碏醯 - chaotic methyl, C1-C6 perfluoroalkoxy, pentafluorosulfanyl , ', · Substituted C1 - C6 haloalkoxy: substituted by one or more substituents selected from the group consisting of a hydrogen atom, a hydroxy a, an atom, a transatom, a C1-hexanoxy group or a_c, an atom, 虱The same or no substitute for the Cl-C6 haloalkylthio group is selected from a hydrogen atom, via its > two, a gas atom, bromine 43 200836629

Cl~C6 halogenated alkoxy group in the same or different atom, iodine atom, Cl-C6 alkoxy; substituted by more than one substituent, substituted C1 - C6 haloalkyl sulfinyl group, sulphur, iodine atom Substituted by a ruthenium atom, a hydroxyl group, a chlorinogen or a different substituent or more, in the plain or C1~C6 haloalkoxy group, the same or substituted C1-C6 haloalkylsulfonyl group: Atom, an intrusive atom, C1_C6 is an oxygen-selective substitution, and is replaced by a substituent, a chlorine atom, and one or more substituents. a U-C6 haloalkoxy group the same or not (compound III) In the formula (1), ^表村轩,子 or 魏化 八2, A3, A4 represents a carbon atom;

Ri and R2 independently of each other represent a hydrogen atom or ci~c Gi, and G2 independently represents an oxygen atom or a sulfur atom.

Qi represents phenyl, which is called from a hydroxyl atom, a C1~C4 alkyl group, a Cl-C4 halogen compound, a work, a Cl-C4 alkyl group, a C2_C4 alkenyl alkynyl group, a C2-C4 tooth Yimei, a C3_C8 Production (1) 14® minus C2 C4 I ^ I L8, C3 — C8 halocycloalkyl, C1 护美, ΐι "ci J: C3 ^oxy, C1-C3 alkylthio, C1-C3 halo 3 stone 4^ 3 sulfinyl, C1 ~ C3 * silk Asian performance ·, C1-C3 ϊί f卞: 〇 one. Haloalkylsulfonyl, Cl, alkylamino, tri-C1-C4 di-anthracene:: exact group, trans-group, α-c4 alkyl group, ci-c4 halogen group, di-, oxy, C1_C4 Chiral oxy group, C1-C4 aerobic acid group, C1 -α carbon, C1_C4 succinylamine, C1 - C4 halogen sulphate, C1 toroxy, C1 - C4 dentate , arsenate, sulphate or the same or different one or more substituents in the group, 44 200836629, heterocyclic group (herein, heterocyclic group means argon, basal, N - Oxidation. butyl group, only pyridine group, hydrazine, furyl, thienyl, fluorenyl, isoindolyl, oxadiazolyl, anthracenyl, isoindolyl, fluorenyl, fluorene Biletyl, miso base, trisalyl, °bazolyl, oxazolyl, 2,3-dihydro-benzo[I,4]20-well, benzo[cut two slogan wah, four Hydrogen bromo or dihydropyranyl.), or - substituted heterocyclic: optionally selected from a halogen atom, a C1 - C4 alkyl group, a C-C4 halogen group, a substituted C1-C4 alkyl group, C2 —C 4 alkenyl, C 2 —C 4 haloalkenyl, C 2 —C 4 alkynyl, C 2 —C 4 i alkynyl, C 3 —C 8 cycloalkyl , C3 — C8 cyclyl, C1—C3 alkoxy, C1-C3 haloalkoxy, C1-C3 sulphur-based, C1-C3 halo-alkylthio, C1-C3 alkylsulfinyl, C1 — C3 i-alkylsulfinyl, C1—C3 alkyl ruthenium, Cl-C3 halogenated ruthenium, C1-C4 arunyl, 2-1, C4, cyano, nitro, hydroxy, — Carbonyl, C1-C4 halogenated carbonyl, C1-C4 alkoxycarbonyl, C1-C4 halocarbonyloxy, C1_C4 alkoxycarbonyl, C1-C4 halooxycarbonyl, C1-C4 alkylcarbonyl, C1 — One or more of C4-alkylcarbonylamino, C1-C4 alkylsulfonyloxy, C1-C4 haloalkyloxy, arylsulfonyloxy, pentafluorosulfoxy or phenyl Substituent (heterocyclic group here means hydrazine, biting group, N-oxidizing η than biting group, pyrimidine group, argonyl group, biting group, thienyl group, carbazolyl group, isoxazolyl group, hydrazine group Diazolyl, thiazolyl, isothiazolyl, ° dioxin, oxime, sulphonyl, tridecyl, oxime, tetradecyl, 2,3~dihydro-benzo[1,4 ]二今井基,苯苯[切工嗤嗤,四氮派基基或Piperidyl.); ^ Q2 is of formula (2)

(wherein Υι denotes C1-C6 alkoxy, C1-C6 haloalkoxy, C1~ thiol, Cl-C6 thiol, C1-C6 alkylsulfinyl, C1_C6 6 cadaveric Sulfonyl, Cl—C6 alkylsulfonyl or C1-C6 haloalkylsulfonyl; where Y5 represents a halogen atom, a Cl—C6 alkyl group, a C1-C6 haloalkyl group, C1~C6 45 200836629 =6 , a-thio group, ketone group γ group == brewing group, C1, silk group, and 24 may be the same or different, and represent a hydrogen atom, a halogen atom, and C1-C6 Y3 represents a halogen atom. (Compound IY) The formula (IIA1=; to "," independently represents a hydrogen atom or a C1_C4 alkyl group; ^2 independently represents an oxygen atom or a sulfur atom; and J is the same or different, and represents a hydrogen atom η represents 〇 to 4 integer; u tooth, you Dingyi - mouse armor,

Qi is phenyl, 'execution, Γ9, alkane C2 - C4 alkenyl, C2-C4 haloalkenyl, C2-C4 di-C8 cycloalkyl, C3-C8-alkyl, alpha oxy, C1-c3 Sulfur-burning, C1-C3 halogen-burning Ϊϋ: base, C1—C3* 烧基亚基基, C1-C3 burning base stone shouting, a-C3 self-filament base, C1-C4 base, ί base, silk , C1-C4 Guji, C1-C4", alkyl alkoxy, C1-C4 halogen carbonyloxy, C1_C4 alkoxy group, -C4 S alkoxy group, C1-C4 silk amine, α- C4 calcined amino group, Q-C4 alkyl tartrazine oxy group, C1-C4 self-calcining sulphate xanthoxy group, aryl stone yellow oxy fluorosulfanyl group or phenyl group with the same or different one or more substitutions A heterocyclic group (wherein a heterocyclic group means pyridyl, pyridyl, N-oxidized pyridyl, pyrimidinyl, morphinyl, furyl, thienyl, oxazolyl, isoxazolyl'yl) , 嗟 基 、, 嗟 嗟 嗟, 嗟 唾 、 、, 各 基 基 基 基 基 基 基 基 基 基 基 基 基 基 基 基 基 基 基 基 基 基 基 基 基 基 基 基 基 基 基 基 基 基 基 基 基 基 基 基 基 基 基 基 基 基 基 基 基 基 基 基 基 基 基 基 基 基 基 基 基 基 基 基 基 基 基 基 基 基 基 基 基 基 基 基 基Benzene [丨46 200836629 tr sitin, tetrahydroindenyl or diterpene). or, substituted heterocyclic: From halogen atom, C1 - C4 filament, C1 - C4 dentate, substituted C1-C4 alkyl, C2-C4 alkenyl, C2-C4 haloalkenyl, C2-C4 alkynyl, C2-C4 halo Alkynyl, C3-C8 cycloalkyl, C3-C8-cycloalkyl, ci-c3 alkoxy, ci-c3 i alkoxy, C1_C3 alkylthio, C1_C3 halogen thiol, C1 - C3 alkyl Sulfonyl, C1 - C3 haloalkyl sulfinyl, C1 - C3, sulphate, Cl - C3, sulphur, yellow, ci - C4, amine, cyano, cyano Nitro, hydroxy, carbonyl, C1 - C4 halane

a few groups, a C1-C4 carbonyloxy group, a C1-C4-alkylcarbonyloxy group, a ci-C4 alkoxy group, a C1-C4-alkoxycarbonyl group, a C1-C4 alkylcarbonylamino group, a ci-C4 haloalkyl carbonyl group Amino, C1 di-C4 alkyl decyloxy, C1 - C4 i decyloxy, aryl methoxy, pentafluorosulfanyl or phenyl, the same or different one or more substituents The heterocyclic group is not pyridinyl, pyridyl, N-oxidized pyridyl, pyrimidinyl, hydrazine, furyl, thienyl, oxazolyl, isoxazolyl, oxadiazolyl, thiazolyl, Isothiazolyl, thiazide=yl, 嘻 嘻 、, imidazo, tri-π, ϋ, 唾, 四, 四, 四, 四, 2, 2, 2, 2, 2 Benzo[1,3]dioxazolyl, tetrahydropentanyl or dihydropiperidyl. 乂仏 is of formula (4)

I, Υ5 may be the same or different 'representing halogen atom, Ci-C6 producing beauty, C1 burning base, C1-C6 grafting oxygen, C1-C6 4 silk base, ci_= burning sulfur i醯 from silk base, New County , C1—c6 age bases, soils, 1-C6 alkylsulfonyl groups, Cl—C6 4 basestones, sulfonyl groups, cyano groups, nitrates Y2, Y4, which may be the same or different, represent a hydrogen atom, a halogen atom, C1_C6 47 200836629 alkyl; Ra represents a halogen atom or a meridine;

Rb and Rc each independently represent a halogen atom, a hydroxyl group, a halogen group, and at least one of Rb and Rc has a "solid gas early", or a C1 - C6 halogen atom or an iodine atom.) ^ ', sub, Hydroxy group, chlorine atom, bromine (compounds V to VIII) Among the above-mentioned compounds I to IV, the compound is a compound of the above-mentioned compounds I to IV. It is a compound of the formula (1) or the formula (5) which can be used for the alkyl group of C1 to C4. In the general formula of the manufacturing method, Q2 is synonymous with q2 in the above [1], or

(2) (wherein, Yi, Y2, Y3 Ys are synonymous.) or general formula (3) 'Y4'Y5^Wi4[l]t^Y^Y2.Y3.Y4

Y

(3) (The Chinese party ΪΓ 7, Υ 8, Υ 9 and butterfly ^ 48 200836629

Α〇) reduction reaction P<>n ¢21)

A2, a3, a4, Gl, r2 Rl, r2, x, n, Qi, Q2 have the same meaning as the Al atom in the above [1], and L means a tooth: Yiyi., general formula (l9)+ In the formula (20), the compound of the formula (21) is a compound which is not dissolved and which is represented by the formula (20). ^ Compounds of the formula (21). This step can also be, for example, water, benzene, toluene, light, two, four, south, m, and carbon, etc. _acetic acid, vinegar, acetic acid, butyl ketone, ketone or denitrile paper 3-H2 - a guanamine such as a diamine; or a mixture of two or more types. , '谷蜊, these solvents can be used alone, alkali such as · triethylamine, tri-n-butylamine, pyridin and other organic bases, sodium hydroxide, potassium hydroxide, etc. ~ monomethylaminopyrazole Potassium and other carbonates; dipotassium phosphate, ^ ^ 钿 金属 metal; sodium bicarbonate, hydrogenation test metal Wei; f-alcohol, ethanol and other test knee acid salts; hydrogenation and so on for the general formula ( 19) The compound indicated is transferred to ^. For this test, you can use it as you like. The appropriate choice for the Wuer Equivalent Fan Park is to be selected. 49 200836629 Reaction temperature, from -2Gt: ~ The reflow temperature of the arsenic, the reaction time, from the number of clocks to 96 hours, the appropriate choice. / For example, in the case where the compound represented by the formula (19) is a mesenyl-based aromatic acid-lowering halide, the m-nitroaromatic carboxylic acid halide can be easily obtained by halogenating the corresponding aromatic carboxylic acid. Manufacturing. A halogenating agent such as a halogenating agent such as sulfinium chloride, sulfinium bromide, light-based chlorinated dish, grass chloroform, phosphorus trichloride or the like. On the other hand, a compound represented by the formula (21) can be produced by reacting a compound represented by the formula (19) with a compound represented by the formula (20) without using a halogenating agent. For example, the production method described in 'Chem. Ber.p. 788 (1970) shows a method in which a benzotriazole additive is suitably used and a ruthenium-dicyclohexyl condensate is used. Other condensing agents used in this case are, for example, monoethyl-3-(3-dimethylaminopropyl)carbonyldiimide, monocarbonylbis-1H-imidazole and the like. Further, another method of producing a compound represented by the formula (21), for example, a method using the hydrazine chloroformate, can be produced by the method according to J. Am. Chem. Soc. ρ. 5012 (1967) A compound represented by the formula (21). The chloroformate used in this case, for example, isobutyl chloroformate, isopropyl chlorate, etc., other than gas phthalic acid § |, for example, diethyl ethyl chlorinated, trimethyl ethyl chloride Wait. The method of using a condensing agent and the method of mixing bribes are not limited to the two types of the former transcripts, the reaction temperature, and the reverse lining, and only the money makes the material significantly hinder the proper reaction of the hydrazine solvent, 'about the reaction temperature, the reaction time, It is also possible to make an appropriate selection depending on the reaction. 1 - (9): a compound of the formula (21) - formula (22), which is represented by the formula (2), which can be represented by the reduction reaction to give a compound of the formula (22). The far-end reaction, for example, using a hydrogenation reaction The method and the method of using a metal compound, tin chloride (1) (anhydrous), iron powder, zinc powder, etc.). The method can be carried out under normal pressure or under pressure in the presence of a suitable solvent towel or a catalyst: a mouse money towel. Catalysts such as κ heterolin, Lenny nickel and other nickel-touch female gas, ruthenium catalyst, ruthenium catalyst, and sensitizer, solvents such as water, methanol, ethanol oximes; ;m four handles and other key shapes 50 200836629 B. The reaction is carried out from αΐ~1_, and the reaction temperature is from -the white, the second, and the m reaction is from the range of several minutes to 96 hours. Each U can be selected to efficiently produce the compound of the formula (22). The dry 哉V哉 method 'for example, n〇rganiC Syntheses, Coil. ν〇1.ΙΠ P453 is used, and tin chloride W (anhydrous) is used as a metal compound. — (4). General formula (22) + general formula (23) - general formula (24) Ϊ ΐίί (ϊ21 silk compound and compound represented by formula (23) in the solvent anti-w^ clothing k general formula (24) The compound may be used in this step. The solvent may be used as long as it does not significantly hinder the progress of the reaction, for example, water, benzene, di-I stupid, etc.; dichloromethane, chloroform, tetrachlorination Carbon or other dentate, tetrahydrofurfuran, hydrazine, 2 -" methoxy ethene, etc. chain or ring - 巧, 乙 k 乙 vinegar, acetic acid butyl g, etc.; methanol, ethanol, etc. Anthraquinones such as aglycone, methylhydrazine, cyclohexanide, etc.; diterpene-based amide, dimercapto-ethyl hydrazine, etc.; 1,3~dimercapto-2, ketone, etc. Solvents, these solvents may be used alone or in combination of two or more. Shallow right, for example: triethylamine, tri-n-butylamine, caiding, 4-dimethylamino-based caffeine, organic bases, hydroxide Alkali metal hydroxides such as sodium and potassium hydroxide; carbonates such as sodium hydrogencarbonate and potassium citrate; metal hydrides such as dihydrogen phosphate monobasic phosphate and trisodium phosphate; Salt _. For the general formula (22) The content may be appropriately selected in the range of _~5 times the molar equivalent. The reaction temperature may be appropriately selected from the range of -2 Gt:~ to the reflux temperature of the listener, and the number of turns between the reactions is from clock to 96 hours. Further, it can also be produced by the method using a condensing agent described in the above (i), or by a mixed acid anhydride method. - 丨 (4): Formula (24) + Formula (25) - Formula (26) a compound represented by the formula (24) and a compound represented by the formula (25) in a solvent or a few/valleys (reactions can produce a compound represented by the formula (26). A compound represented by the formula (25), such as methyl iodide, Molybdenum, desertified propane and other halogenated alkanes, chlorinated ethylidene groups, halogenated groups, etc. In addition, this step may use an appropriate test or solvent, such as m (1) For example, the reaction temperature, the reaction time, and the like may be exemplified by the above-mentioned 1 (i) according to 51-200836629. Further, in other methods, the compound represented by the general formula (25) is changed to An alkylating agent such as mercaptosulfuric acid or diethylsulfonic acid can be reacted with a compound represented by the formula (24) to produce a compound represented by the formula (26). Production Method 2

In the formula (20), the formula (23) and the formula (27) to the formula (30), E represents a C (=

Gi)- or -S02-,^, A2, A3, A4, G, G2, &, R2, X, n,

Qi, Q2 and Ai, A2, A3, A4, G]L, G2, R2, x, n in the above [1]

Qi^Q2 is synonymous, and L represents a functional group having a detachment ability such as a halogen atom or a hydroxyl group, and Hal represents a halogen atom. 2—(i) ·· (27)+ Formula (23)—Formula (28) The compound represented by the formula (27) is used as a starting material, and the conditions and the formula are as described in the above 1-1. The compound represented by the formula (28) can be produced by reacting the compound represented by (23). 2~(ii): General formula (28) - General formula (29) • By using the compound represented by the general formula (28) with sulfinium chloride, chloroform, phosgene, hydroxy chloride, phosphorus pentachloride, A compound represented by the formula (29) can be produced by a known conventional method of a reaction such as phosphorus trichloride, sulfinium bromide, phosphorus tribromide or diethylaminosulfur difluoride. — 2 — (m): Formula (29) + Formula (2〇)—Formula (3〇) By using a compound represented by the formula (29) and a compound represented by the formula (20), 1) The conditions described in the reaction can produce a compound represented by the formula (30). _ 2~(iV): general formula (28) + general formula (2〇) - general formula (3〇) = a compound represented by the formula (28), according to the above-mentioned item 1, the use of a condensing agent strip = or The compound represented by the formula (30) can be produced by reacting with a compound represented by the formula (2) using the conditions of the mixed acid anhydride method. Manufacturing Method 3 52 200836629

A a

Ο ^ Rawweisheng test

% X mn β2) C23) aA4^Γγ' OOn 1! 阙 (in the general formula (23) and the general formula (31) to the general formula (33), Ε represents -c( = Gi)- or ~ lit 2„, Gl, Rl, R2, X, n, Ql, Q2_, W〒 a halogen atom, a hydroxyl group, etc. having a dissociable functional group.) 3-1: General formula (31) - general formula (32), according to Synthesis Page (1"3 years) and 仏9 page (carrying, the known conditions, will pass 1) silk compound without Weisheng reagent reaction, can be prepared, the compound represented by the formula (32). Solvent The conditions such as the reaction temperature are not limited to those described above. Inch 乂 - 3-(8): Formula (32) + Formula (23) - Formula (33) By using the compound represented by the formula (32) The compound represented by the formula (23) can be produced according to the conditions described in the above-mentioned product, and the compound represented by the formula (33) can be produced.

(35) (38) ^ (In the general formula (34) to the general formula (36), \, A2, A3, A4, Rj, R2, X, n,

Qi, Q2 are synonymous with Ai, A2, A3, A4, K, r2, X, n, Qi, & in the above [1]. From the compound represented by the formula (34), the compound represented by the formula (35) and the formula (36) can be produced according to the conditions described in the above 3-1. The conditions such as the solvent and the reaction temperature are not limited to those described in the literature. These two compounds can be easily separated and refined by the known separation technology of 53 200836629, such as rubber column chromatography.

~^令1 ^A^Y' (X)n i (39) (23) R2

, '2 person' R (X)n ό °2 (38) >On Ji (37)

(In the general formula (23) and the general formula (37) to the general formula (39), e 2 S02-, , A2, a3, a4, ., &, R, (1), "A3, A4, Gl, G2, Ri, Wn, Q1, Q2^ meaning 'L" means that a halogen atom, a hydroxyl group or the like has a cleavage center, Qi, Q2, and 5-(i): a formula (37) of a formula (10). J. Org·Chem· Ρ·280 (1958) describes the yin-chemical reaction of the yin-chemical reaction (shown in the literature) as long as it is used without any significant impediment to proper ruminant Wp can be used, and the reaction temperature and reaction time can be appropriately selected depending on the reaction. Further, in addition to ammonia, the aminating agent can also be exemplified by mercaptoamine, ethylamine, etc. ^ 5~(9)·· Formula (38) + Formula (23) - Formula (39) By reacting a compound represented by the formula (38) with a compound represented by the formula (23), it can be produced according to the conditions described in the above i- a compound represented by the formula (39). Manufacturing method 6 54 200836629

(43, 2) <44-a> (In the general formula (40) to the general formula (44-2), R2, Y2, and Y4 are synonymous with R2, Y2, and Y4 in the above [1], and each of Yi'Ys Independently represents a hydrogen atom, a methyl group, a gas atom, a bromine atom, or an iodine atom, and Rf represents a Cl—C6 perfluoroalkyl group, and m is 1, 2.) 6 — (i) • Formula (4〇)+ (41) - General formula (42) According to the method described in J. Fluorine Chem. ρ. 207 (1994), the amine thioguanidine represented by the general formula (4〇) and the moth represented by the general formula (41) The compound represented by the formula (42) can be produced by a halogen group reaction.

a compound represented by the formula (41) (an alkyl halide), for example, trifluorodecane iodide, pentafluoroethane iodide, heptafluoro-n-propane iodide, heptafluoroisopropane iodide, nonafluoroheptide Or n-butane, hexafluoro-2-butane iodide, etc., which can be suitably used in the range of 1 to 10 times the molar equivalent of the compound represented by the formula (4). The solvent to be used in this step is not limited to the solvent described in the above document, and the solvent thereof may be, for example, water, aromatic hydrocarbons such as benzene, toluene or xylene; dichlorohydrazine or chloroform tris. Halogenated hydrocarbons such as carbon; diethyl ether, dioxane, tetrahydrofuran, U-dimethoxyethane-specific chain or cyclic ether; esters such as ethyl acetate and butyl acetate, methanol, ethanol, etc. Alcohols; acetone, methyl isobutylene, cyclohexanone; guanamines such as dimethylformamide, dimethylacetamide; nitriles such as acetonitrile; U-dimethyl-2-oxazolidine For example, sunbatch, If triterpenoid, etc., these solvents may be used alone or in combination with two kinds of δ. Especially the polar solution is good. The reaction temperature can be selected from ~ used 4, the reaction _ can be from a few minutes to the minute of the appropriate 55 200836629 selection. 6 — (ii): General formula (42)—general formula (43)

From the plain paste, it is possible to produce a compound, for example, a method described in Synth. C〇_UILp 126 1 (1989). J ί ΐ ΐ 剂 例如 例如 例如 例如 ’ ’ ’ 氯 氯 氯 氯 氯 氯 氯 氯 氯 氯 氯 氯 氯 氯 氯 氯 氯 氯 氯 氯 氯 氯 氯 氯 氯 氯 氯 氯 氯 氯 氯 氯 氯The substance is suitably used in the range of 1 to 10 times the molar equivalent. The solvent can also be used in the t step, and the solvent to be used is not limited. The solvent can be carried out as long as it does not significantly hinder the reaction, and the chain or ring of the gas is entangled, and the ring is ring-shaped or ring-shaped. t 3 二 、 、 、 、 、 、 、 、 、 、 、 、 、 、 、 、 、 、 、 、 、 、 、 、 、 、 、 、 、 、 、 、 、 、 、 、 、 、 、 、 、 、 、 、 、 、 、 The above mixed use =, the temperature, can be selected from -2 叱 ~ using the reflux temperature of the solvent, the reaction range can be selected from the range of several minutes to 96 hours. ' ^ 1 Qiu): Formula (43) - Formula (44) ^ Suitable oxidizing agent, which can produce a compound of the formula (μ). For example, the method described in 丄 etrahedron Lettp. 49 55 (1994). A few oxidizing agents are, for example, organic peracids such as m-chloroperbenzoic acid, quinone iodide bromide, iodonium benzyl, and tert-butyl hypochlorite. In this step, the solvent is not limited to the solvent described in the above-mentioned literature, and the solvent may be used only if it does not interfere with the reaction. These solvents may be used alone or in combination. Especially polar solvents are preferred. The reaction temperature is from 2 to 2:t to make the temperature of the agent, and the reverse phase is selected from several minutes to 96 small details. 56 1 - (4) · Formula (43) - Formula (43-2) 200836629 By using a suitable thiolating agent, a compound of the formula (43) can be produced from the compound of the formula (43). ---·2) (wherein, one of Yi and Y5 must represent a thiol group.) A compound represented. This method is, for example, the method described in Tetrahedron Lett ρ. 6237 (2000). 6 — (ν) · · Formula (43-2)—Formula (44-2) • According to the method described in 6—(iii) above, the formula (44~2) can be produced (in the formula, at least Υ! One of Y, and Y5 must represent a compound represented by a methyl group.). Further, a compound represented by the formula (43), the formula (44), the formula (43-2) or the formula (44-2) can be produced, and the formula (1) can be produced by appropriately selecting the method described above. Or a compound represented by the formula (5). In the same manner, I, Υ2, γ4, and ¥5 in the formula (2) can be produced as a C1-C6 perfluorosulfothio group, a Cl-C6 perfluoroalkyl sulfhydryl group, and a Cl-C6 perfluoroalkyl group. The acid group is a compound represented by the formula (1) or the formula (5). Soil ‘, manufacturing method 7

(4?)

Τ Τ γ6) ^; (, 47) ' 5R2 'Y2 'Y4 2 ") The compound represented by the formula (45) is used as a starting material, and the "secret, f-making method" can be used to produce the formula (1) or the formula (3). (4) (4) The description of the chest is not complete (3) Basic, (1) 峨, C1, C6 slender 57 200836629 λΛ; 〇 2 % (Χ) π (48) (General formula (48) and general formula (49), (4S&gt ; Q2 and the above [1] Ά 'α 1 2, 3, A4, X, n, G2, R2, the compound represented by the formula (48) and the solvent 3) 4 South 'nj, 1, (3⁄4 羲. The compound represented by the formula (49). The test "reactant reaction" can be used to produce a compound which hinders the reaction, for example, a m-methyl hexyl burned aquarium hydrocarbon; benzene, 兀辰Hyun, burn, chloroform, tetrachlorinated, 丨2~_ == I This compound has no hydrocarbons; dichlorodecane, tetrahydrofuran, 1,2-dimethoxy: dihalogenated hydrocarbons; diethyl ether , such as acetonitrile, acetonitrile, dimethyl ketone, dimethyl ketone, ketones, acetonitrile, acetonitrile, dimethyl ketone, etc.; Cyclohexanone, gas 1,3-dimethyl-2l, phase alcohol, ethanol, etc. a solvent such as methyl (tetra) or water, a base such as a carbonate such as triethylamine or dipotassium; a dish of a sulphuric acid; a sodium sulphate; a metal carbonate; Iso-f, acid salt; hydrogenation and other hydrogenation test ethyl equivalent range suitable for dimeric can be 'in _ to 5 times mol = fluoride Ϊ ΪΐΧ峨, desertified E-burn, trifluoromethane, broken 2 , 2, 2 —; Women's toothed propylene, brominated propyl sulphate, dimethyl sulphur as a compound shown in '1 to 5 times more than use, or used as a solvent. The compassion is further reduced to 80 ° to the reflux temperature of the solvent. The reaction time is from the range of 58 to 86,366,290 to 96 hours.

(X)n «I , q2 (22) (50) 5 (In the general formula (22) and the general formula (50), Al, a a, λ v η p 〜, Q2 and Al, a2 in the above Π] , a3, 2a A3x A4, X/n, G2, Rl, synonymous.) 2 A3 dn, G2, Rl, R2, Q2 9 - (i): general formula (22) - general formula (5〇) The compound represented by the formula (10) can be produced by a reaction of sputum and a reaction of adding a catalyst to the reaction of 虱(iv). A 33 of it can be subjected to the reaction, for example, hexane, cyclohexane, ^ 3; benzene, f 曱 st, toluene and other aromatic hydrocarbons; dichloromethane, tetrazolla, 1, 2 - Dichloroethane, etc. - sulfonated hydrocarbons; di-ethyl, tetrahydrogen, dimethoxyethane; dimercaptomethylamine, dimethylamine, acetonitrile, propionitrile, etc. ; propyl hydrazine, methyl isobutyl hydrazine, cyclohexyl hydrazine, ethyl ketone, acetic acid, ethyl acetate, (10) butyl I, etc.; 1,3 dimethyl-2, taste, ketone, oxime An alcohol such as dimethyl sulfite, sterol or ethanol; or a solvent such as water. The solvent may be used singly or in combination of two or more. Catalyst, for example, palladium-carbon, hydrogen peroxide, palladium such as carbon Catalysts, nickel catalysts such as Lenny nickel, cobalt catalysts, platinum catalysts, ruthenium catalysts, ruthenium catalysts, etc. Classes such as A plate, acetaldehyde, propionaldehyde, trifluoroacetaldehyde , difluoroacetaldehyde, fluoroethylene, rat B, a mouse B, trichloroethane, desert acetic acid and other acids. Ketones such as acetone, perfluoroacetone, methyl ethyl ketone and other ketones, reaction pressure at 1 atmosphere to The range of 100 air pressure can be appropriately selected. The reaction temperature The degree can be appropriately selected from the range of TC to the reflux temperature of the solvent, and the reaction time is from several minutes to 96 ^ 59. 59 200836629 9 one (ii): general formula (22) general formula (50) (he The compound represented by the formula (22) can be produced by treating the compound represented by the formula (22) with a __-type reactant to produce a compound represented by the formula (50). The heart-like solvent can be used as long as it does not significantly hinder the reaction. For example, aliphatic hydrocarbons such as methylcyclohexane; stupid, xylene, oxime I, aramid, chloroform, carbon tetrachloride, i 2 - an aromatic hydrocarbon; dichloromethyl fumon, 1 , 2-dimethoxyethane, etc. _; dimethylmethyl _ = acetic acid amine, etc.; acetonitrile, propionitrile and other nitrile _ acetone, methyl butyl residue, 5 methane ethyl ketone and other ketones; The purpose is to convert acetic acid to cis; i 3" dimethyl hexanol, fluorenone, cyclarene, dimethyl sulfoxide, methanol, alcohol: methyl; sodium saliva solvent can be used alone or 2 _ Mixed production of water into the 'such as the chemical ^ fine, such as pain b sodium, money cyanide, Jane San Yi __ nitrogen acetic acid, three gas, Jun, difluoroethylene, defeated. B [formaldehyde such as dichloroacetaldehyde or bromoacetaldehyde Ketones, for example, acetone, perfluoropropene, methyl ethyl hydrazine, etc. ^ The temperature should be appropriately selected from -2 (TC to the reflux temperature of the solvent, from the counterclockwise to the 96-hour range. Between the inch and the number of knives 9" (iii wide formula (22) - general formula (5 〇) (the phantom compound in the solvent or no solvent, anti-sounding agent with the sputum, as long as the solvent does not interfere with the reaction, For If ^ J base ring, aliphatic hydrocarbons; benzene, dimethyl stupid, Ai Yifang

i, charcoal, n-dichloroethane and other self-acidified hydrocarbons; diethyl H-ethylamine; nitrile such as acetonitrile, propionitrile = acesulfame, sulfone, dimethyl sulfoxide, Methanol, earth. Ten f solvent can be used alone or in combination of two or more kinds of water; a hydrophile, such 60 200836629 a mercapto grouping agent, for example, citric acid, formic acid, fluoroantimonic acid, sulfhydryl ( 2,2-dimercaptopropionic acid and other phthalic anhydrides; formic acid esters such as phenyl phthalate; pentafluorobenzaldehyde, slogan, etc. The γ γ additive is, for example, an inorganic acid such as sulfuric acid, an organic acid such as formic acid, a boron cyanide such as sodium borohydride or sodium borohydride, boric acid or hydrogenated bell. The reaction temperature is from one to twenty. (: It is sufficient to use the reflux temperature of the solvent and the reaction time from the range of several to eight hours to 96 hours.

(53) (in the general formula (22), the general formula (25), the general formula (S1), the general formula and the general formula (53), A2, A3, A4, G2, Ri, R2, X, n, (^ And q2 are synonymous with Ai y A3, A4, G2, R!, R2, x, n, (^, q2 in the above (1), Hal represents halogen 2, 10 - (i): general formula (22) + general formula ( 51)->General formula (52), °) A compound represented by the known condition (22) described in Tetrahedron Letters ρ·3789 (1999) or the like is reacted with a compound represented by the formula (51) to produce a general formula. Conditions such as a solvent, a reaction temperature, and the like are not limited to those in the literature. (52) 10 - (9): Formula (52) + Formula (25) - Formula (53) σ. The formula (52) is represented. The compound represented by the formula (25) can be produced by reacting the compound with the compound represented by the formula (25) according to the conditions described in (iv).

(In the general formula (20), the general formula (54), the general formula (55), and the general formula (56), &, a A4, G2, Ri, R2, X, n, Qi, (3⁄4 and the above [1] a, a, a 八 3, 1 2, A3, A4, 61 200836629 G2, r2, X, η, Qi, Q2 are synonymous, Hal represents a halogen atom.) U — (i): general formula (54 - General formula (55) ^ The compound represented by the formula (54) can be produced according to the conditions described in the above 2-(2). η - © : Formula (55) + General formula (20)-> General formula (56) - A compound represented by the formula (55) and a compound represented by the formula (2) can be produced by reacting according to the conditions described in the above (1). a compound represented by the formula (56): 11 - (iii): a compound represented by the formula (54) + a formula (20) - a compound represented by the formula (54), which is condensed according to the above 1-1 The compound of the formula (56) can be produced by reacting the compound with the compound represented by the formula (20) under the conditions of the mixed acid anhydride method, and the compound represented by the formula (56) can be produced. After the reaction is completed, it can be separated from the reaction = 2, and if necessary, recrystallization, column chromatography, and steaming can be carried out. ^ Fine coating operation. And 'the desired product may not be isolated from the reaction system, and secondly for the reaction steps explicitly =

Bu" represents a second butyl group, rt-B #-hydrogen atom, "〇" means an oxygen atom, "S" means "H" means N" means a nitrogen atom, "F" means a fluorine atom, "= sub, a C" "carbon atom base, "s-Bu · gentleman 筮 - D, I, 1 1 Bu" means

Cl" means chlorine atom, fluoromethyl group

Br represents a bromine atom, "I" represents an iodine atom, "CF3, Table 1 (A) ^

62 200836629 Table 1(1) Compound number Qi a,2 A,3 A,4 Ri r2 〇2 1-1 Phenyl CH CH CH CH HH 2,4-Dibromo-6-trifluoromethylthiophenyl 1-2 2 -Methylphenyl CH CH CH CH HH 2,4-di>odor-6-dimethylthiophenyl 1-3 3-methylphenyl CH CH CH CH HH 2,4-di> -6-dimethylthiophenyl 1-4 4-methylphenyl CH CH CH HH 2,4-dibromo-trifluoromethylsulfophenyl 1-5 2-ethylphenyl CH CH CH CH HH 2,4-二广-6-di-gasmethylthiophenyl 1-6 3-ethylphenyl CH CH CH H H 2,4-di> odor-6-di-m-methylthiophenyl 1-7 4-ethylphenyl CH CH CH CH HH 2,4-di,/odor 6-dioxomethylthiophenyl 1-8 2-fluorophenyl CH CH CH HH 2,4-di >Smelly-6-di-denylmethylthiophenyl 1-9 3-fluorophenyl CH CH CH HH 2,4-di>Smell-6-dimethylthiophenyl 1-10 4-gas Phenyl CH CH CH CH HH 2,4-di>Smell-6-didonylmethylthiophenyl 1-11 2-chlorophenyl CH CH CH CH HH 2,4-di>Smell-6-II Murine thiophenyl 1-12 3-chlorophenyl CH CH CH CH HH 2,4-di- -6-di-m-methylphenylphenyl M3 4-chlorophenyl CH CH CH H H 2,4- Dibromo-6·trifluoromethylthiobenzene 1-14 2-Bromophenyl CH CH CH CH HH 2,4-di>Smell-6-dimethylthiophenyl 1-15 3-bromophenyl CH CH CH CH HH 2,4-di&gt Odor-6-disintegrated methylthiophenyl 1-16 4-bromophenyl CH CH CH CH HH 2,4-di>Smell-6-disindolylthiophenyl 1-17 2-Ethylene CH CH CH CH HH 2,4-Dibromo-6-trifluoromethylthiophenyl 1-18 3-Mothyl CH CH CH CH HH 2,4-Dibromo-6-trifluoromethylthiobenzene Base 1-19 4-Ethyl CH CH CH CH HH 2,4-di>Smell-6-dimethylthiophenyl 1-20 3-cyanophenyl CH CH CH HH 2,4- II>Smell-6-di-mercaptothiophenyl 63 200836629 Table 1(2) Compound number Qi a,2 a,3 A,4 Ri r2 q2 1-21 4-cyanophenyl CH CH CH CH HH 2,4-dibromo-6-trifluoromethylthiophenyl 1-22 2-nitrophenyl CH CH CH HH 2,4-dibromo-trifluoromethylthiophenyl 1-23 3-mercaptophenyl CH CH CH CH HH 2,4-di>odor-6-difluoromethylthiophenyl 1-24 4-pyridylphenyl CH CH CH HH 2,4-di> Odor-6-disorder methylthiophenyl 1-25 2-aminophenyl CH CH CH CH HH 2,4-di>odor-6-dimethylthiophenyl 1-26 3-amino Phenyl CH CH CH CH HH 2,4-di & Gt-6-dimethylthiophenyl 1-27 4-aminophenyl CH CH CH H H 2,4-di>odor-6-dimermethylthiophenyl 1-28 2- Trifluoromethylphenyl CH CH CH H H 2 2,4-dibromo-6-trifluoromethylthiophenyl 1-29 3-trifluorodecylphenyl CH CH CH CH HH 2,4-di> Odor-6-dimethylthiophenyl 1-30 4-trifluoromethylphenyl CH CH CH CH Π H 2,4-di > odor-6-disorder methylthiophenyl 1-31 2 -hydroxyphenyl CH CH CH H H 2,4-di--6-difluoromethylthiophenyl 1-32 2-methoxyphenyl CH CH CH CH HH 2,4-di>odor-6- Di-mercaptothiophenyl 1-33 3-methoxyphenyl CH CH CH CH HH 2,4-di >odor-6-dioxomethylthiophenyl 1-34 4-methoxyphenyl CH CH CH CH HH 2,4-di>Smelly-6·dimethylthiophenyl 1-35 2-phenoxyphenyl CH CH CH H H 2 2,4-di>Smell-6-II Fluoromethylthiophenyl 1-36 4-(1,1-dimethylethyl)phenyl CH CH CH HH 2,4-dibromo-6-trifluoromethylsulfophenyl 1-37 3- (Dimethylaminophenyl) CH CH CH CH HH 2,4-Dibromo-6·trifluorodecylthiophenyl 1-38 4-(dimethylaminophenyl) CH CH CH CH HH 2 ,4-dibromo-6-trifluorodecylthiophenyl 1-39 4-Trifluoromethoxyphenyl CH CH CH CH HH 2,4-di>Smell **6-Dimethylthiophenyl 1-40 2-(Ethylamino)phenyl CH CH CH CH HH 2,4-di>Smell-6-di-mercaptothiophenyl 64 200836629 Table 1 (3) It Compound No. Qi Α5ι a,2 A,3 A,4 Ri r2 Q2 1 - 41 : Ethylamino)phenyl CH CH CH H H : 2,4-dibromo-6-trifluoromethylthiophenyl 1-42 4-(ethinylamino)phenyl CH CH CH CH HH : 2,4-dibromo-6-trifluoromethylthiophenyl 1-43 2-acetoxyphenyl CH CH CH H H : 2,4-dibromo-6-trifluoromethylthiophenyl 1-44 2-(methoxycarbonyl)phenyl CH CH CH H H 2,4-di>odor-6-dioxomethylthiophenyl 1-45 4-(indolylcarbonyl)phenyl CH CH CH CH HH 2,4-di>odor-6-dimethylthiophenyl 1-46 2,3-dimercaptophenyl CH CH CH CH HH 2,4-dibromo-6-trifluoromethyl Thiophenyl 1-47 2,4-dimethylphenyl CH CH CH HH 2,4-di--6-difluoromethylthiophenyl 1-48 2,6-dimethylphenyl CH CH CH CH HH 2,4-dibromo-6-trifluorodecylthiophenyl 1-49 2,3-diphenylphenyl CH CH CH H 2,4-di>odor-6-dimethylmethyl Thiophenyl 1-50 2,4-diphenyl CH CH CH CH HH 2,4-Dibromotrifluoromethylsulfophenyl 1-51 2,5-difluorophenyl CH CH CH CH HH 2,4-dibromotrifluoromethylthiophenyl 1 -52 2,6-dimerylphenyl CH CH CH HH 2,4-dibromotrifluoromethylsulfophenyl 1-53 3,4-difluorophenyl CH CH CH HH 2,4-di >Smelly-6-dimethylthiophenyl 1-54 3,5-diphenylphenyl CH CH CH H H 2,4-di>Smell-6-dimethylthiophenyl 1-55 2,3-dichlorophenyl CH CH CH CH HH 2,4-di>odor-6-di-mercaptothiophenyl 1-56 2,4-dichlorophenyl CH CH CH CH 2,4 -二> Wu-6-di-mercaptothiophenyl 1-57 2,5-dichlorophenyl CH CH CH H H 2 2,4-dibromo-6-trifluoromethylthiophenyl 1-58 2,6-digas base CH CH CH CH HH 2,4-dibromo-6-trifluoromethylthiophenyl 1-59 3,4-dichlorophenyl CH CH CH HH 2,4-di 〉 odor-6-dimercaptothiophenyl 1-60 2,4-dinitrophenyl CH CH CH H H 2,4-dibromo-6-trifluoromethylthiophenyl 65 200836629 Table 1 ( 4) Compound number Qi A, a, 2 a, 3 A, 4 Ri r2 q2 1-61 3,4-dinitro-phenylphenyl CH CH CH HH 2,4-dibromo-6-trifluoromethyl Thiophenyl 1-62 2,6-dimethoxyphenyl CH CH C H CH HH 2,4-dibromo-6-trifluorodecylthiophenyl 1-63 3,5-dimethoxyphenyl CH CH CH CH HH 2,4-dibromo-6-trifluorodecyl Thiophenyl 1-64 3-methyl-4-nitrophenyl CH CH CH H H 2 2,4-di> odor-6-di-decylthiophenyl 1-65 5-amino-2- Gas phenyl CH CH CH CH HH 2,4-di > odor-6-dimethylhydrazine phenyl 1-66 3-fluoro-2-methylphenyl CH CH CH H H 2,4-dibromo -6-trifluoromethylsulfophenyl 1-phenyl 2-gas-5-decylphenyl CH CH CH CH HH 2,4-di > odor-6-disorder methylthiophenyl 1-68 4 - gas-3-mercaptophenyl CH CH CH CH HH 2,4-di>Smell-6-dimethylthiophenyl 1-69 5-Gas-2-Gentocylphenyl CH CH CH H H 2 ,4-二漠-6-二气methylthiophenyl 1-70 2-gas-6-filled phenyl CH CH CH CH HH 2,4-di> odor-6-dimethylthiophenyl 1-71 2-1-5-Dimethyl nonylphenyl CH CH CH CH HH 2,4-Dibromo-6-trifluoromethylthiophenyl 1-72 2-chloro-4-indolylphenyl CH CH CH CH HH 2,4-dibromo-6-trifluorodecylthiophenyl 1-73 2-chloro-4-phenylphenyl CH CH CH CH HH 2,4-dibromo-trifluoromethylthiobenzene 1-74 2-Chloro-6-gas phenyl CH CH CH CH HH 2,4-di>Smell-6-trisole Phenyl 1-75 3-chloro-4-1 phenyl CH CH CH CH HH 2,4-di> odor-6-two gas thiophene 1-76 4-chloro-2-phenyl phenyl CH CH CH CH HH 2,4-di>Smell-6-dihalohydrazinophenyl 1-77 4-Ga-2-indole basic CH CH CH CH HH 2,4-di>Smell-6- Dimethyl thiophenyl 1-78 3-methoxy 4-nitrophenyl CH CH CH H H 2,4-dibromo-6-trifluoromethylthiophenyl 1-79 2-methoxy 4--4-phenylphenyl CH CH CH HH 2,4-di>odor-6-dimethylthiophenyl 1-80 2,3,4-trifluorophenyl CH CH CH HH 2, 4-II>Smell-6-dimethylthiophenyl 66 200836629 Table 1(5)

Compound number Qi Α, α, 2 A, 3 A, 4 Ri r2 q2 1-81 2,4,6-trimethylphenyl CH CH CH HH 2,4-di>Smell-6-two gas Thiophenyl 1-82 2J,6-trifluorophenyl CH CH CH HH 2,4-dibromo-6-trifluorodecylthiophenyl 1-83 2,4,5-trimethoxyphenyl CH CH CH CH HH 2,4-di>Smell-6-di-mercaptothiophenyl 1-84 3,4,5-trimethoxyphenyl CH CH CH CH HH 2,4-di> Odor-6-tris-methylthiophenyl 1-85 2,3,4,5,6-pentafluorophenyl CH CH CH HH 2,4-di>odor-6-difluoromethylthiobenzene 1-86 2-biphenyl CH CH CH CH HH 2,4-di>odor-6-dimethylthiophenyl 1-87 3-biphenyl CH CH CH CH HH 2,4-di> Odor-6-difluoromethylthiophenyl 1-88 1-nyl CH CH CH CH HH 2,4-di>odor-6-di-mercaptothiophenyl 1-89 2-naphthyl CH CH CH CH HH 2,4-di>Smell-6-di-mercaptothiophenyl 1-90 ^ ratio 17-but-2-yl CH CH CH CH HH 2,4-di,/odor-6-diox Mercaptothiophenyl 1-91 ° ratio -3--3-CH CH CH CH HH 2,4-di > odor-6-difluoromethylthiophenyl 1-92 oxime.定-4-yl CH CH CH CH HH 2,4-di>Smell-6-di-mercaptothiophenyl 1-93 2-methylindole-5-yl CH CH CH CH HH 2,4-二浪-6-二气曱 thiophenyl 1-94 3-methylpyridin-2-yl CH CH CH H H 2,4-dibromo-6-trifluorodecylthiophenyl 1-95 2- Gas 吼唆·^-based CH CH CH CH HH 2,4-di> odor-6-difluoromethylthiophenyl 1-96 2·gas 11 is more than 唆-3-yl CH CH CH CH HH 2, 4-II>Smell-6-di-methylmethylthiophenyl 1-97 2-Chloridine-4-yl CH CH CH CH HH 2,4-di>Smell-6-disorder methylthiophenyl 1-98 Di-gas 吼17 定-6-yl CH CH :CH CH :HH 2,4-di>odor-6-di-mercaptothiophenyl 1-99 2-gas-based CH CH [CH CH :HH 2,4-di>Smell-6-dimethylthiophenyl 1-100 5-molar ratio °-2-yl CH CH [CH CH :HH 2,4-di > odor - 6-dimethylthiophenyl 67 200836629 Table 1 (6)

Compound No. Qi Α, α, 2 A, 3 A, 4: RiJ Q2 1-101 4-Trifluoropyridylpyridinyl CH CH CH < CH HH: 2,4-di> Odor-6-dioxin Methylthiophenyl 1-102 3 -base ratio. -2 -based CH CH CH丨CH HH: 2,4-dibromo-6-trifluoromethylsulfophenyl 1-103 2-phenoxyacridin-3-yl CH CH CH CH HH: 2, 4-II>Smell-6-di-mercaptothiophenyl 1-104 2-methylsulfate ratio 唆-3-yl CH CH CH CH HH 2,4-di>Smell-6-two gas Thiophenyl phenyl 1-105 2,6-dimethoxyacridin-3-yl CH CH CH CH HH 2,4-di>odor-6-dioxadecylthiophenyl 1-106 2,3- Dioxin σ ratio u--5-based CH CH CH CH HH 2,4-dibromo-6-trifluoromethylthiophenyl 1-107 2,5-digas 11 ratio °-3-yl CH CH CH CH HH 2,4-di>odor-6-dimethylthiophenyl 1-80 2,6-diox ratio. Ding-3-yl CH CH CH CH HH 2,4-di>Smell-6-dimethylthiolocenyl 1-109 3,5-digas^specific 唆-bucket-based CH CH CH CH HH 2 , 4-II>Smell-6-dispeltylthiophenyl 1-110 mouth bite-^^-emulsified ^-based CH CH CH CH HH 2,4-di--6-di-methylsulfur Phenyl 1-111 N-mercaptopyrrol-2-yl CH CH CH CH HH 2,4-di>Smell-6-dimethylthiophenyl 1-112-rhept-2-yl CH CH CH CH HH 2,4-di> odor-6-dimethylthiophenyl 1-113 2-indenyl 0 ratio. Well-5-based CH CH CH CH HH 2,4-di>odor-6-dimethylthiophenyl 1-114 4-difluoromethyl σ-dense-5-yl CH CH CH CH HH 2 ,4-二>Smell-6-dimethylthiophenyl 1-115 11 Fu-2-yl CH CH CH CH HH II:^-二漠^^-二象曱基疏phenyl 1- 116 吱 -3--3-yl CH CH CH CH HH 2,4-di > odor-6-di 1 methyl thiophenyl 1-117 2-tetrafurfuryl CH CH CH CH : HH 2, 4- >Smelly-6-di-murmurylthiophenyl 1-118 3-tetramyl CH CH CH CE :HH 2,4-di>Smell-6-dimethylthiophenyl-1-19 Benzo-bromo-2-yl CH CH CH CH [HH 2,4-di> odor-6-dimethylthiophenyl 1-120 tetrahydrofuran-2-yl CH CH CH CH [HH 2 ,4-dibromo-6-trifluorodecylthiophenyl 68 200836629 Table 1 (7) Compound number Qi Α, α, 2 A, 3 A, 4 Ri r2 Q2 1-121 2-methyl-5,6 Dihydro-4H-indole-3-yl CH CH CH CH HH 2,4-di>odor-6-dimethylthiophenyl 1-122 σ cephen-2-yl CH CH CH CH HH 2,4-di> odor-6·dimurazolylthiophenyl 1-123 oxime-3-yl CH CH CH CH HH 2,4-di> odor-6-di-mercaptosulfur Phenyl 1-124 3-methylthiophene-2·yl CH CH CH CH HH 2,4-di>Smell-6-di-gasmethylthiophenyl 1-125 2-Phase σ-secen-4-yl CH CH CH CH HH 2,4-di>Smell-6-II Gas methylthiophenyl 1-126 2-methyl σ-sept-5-yl CH CH CH CH HH 2,4-di > odor-6-dimethylthiophenyl 1-127 3-chlorothiophene -2-yl CH CH CH CH HH 2,4-di>odor 6-di-mercaptothiophenyl M28 2-chloro sigma-5-yl CH CH CH CH HH 2,4-di -6 -trifluoromethylthiophenyl 1-129 3 - > skoxin-2-yl CH CH CH CH HH 2,4-di > odor-6-di-methylthiophenyl 1-130 2- Bromoporphin-5-yl CH CH CH CH HH 2,4-di>odor-6-dimethylthiophenyl-1-31 3 -deca-but-2-yl CH CH CH CH HH 2, 4-II>Smell-6-dimethylthiophenyl 1-132 3-phenylthiophen-2-yl CH CH CH CH HH 2,4-dibromo-6-trifluoromethylthiophenyl 1 -133 2,4-dimethyldecaxene-5-yl CH CH CH CH HH 2,4-di>odor-6-difluoromethylsulfanyl 1-134 benzo-xethen-2- -Based CH CH CH CH HH 2,4-di>Smell-6-disorder methylthiophenyl 1-135 4-Nitro-1pyrrole-2-yl CH CH CH CH HH 2,4-II -6-dimethylthiophenyl 1-136 3-ethyl-3-oxapyrazol-4-yl CH CH CH CH HH 2,4-di>odor-6-dimethylthiophenyl 1-137 1-methyl-3-nitro-1Η-.嗤-4-yl CH CH CH CH HH 2,4-di,/odor 6-dimethylthiophenyl 1-138 3-chloro-1-indolyl-1 Η-pyrazole-4-yl CH CH CH CH HH 2,4-di>Smell-6-trifluoromethylthiophenyl 1-139 3-bromo small methyl-1 Η-pyrazole-4-yl CH CH CH CH HH 2,4-II Bromo-6-trifluoromethylthiophenyl 1-140 1-methyl-3-fluoromethyl-1 Η- ° than 嗤-4-yl CH CH CH CH HH 2,4-di > Dimethylthiophenyl 69 200836629 Table 1 (8) Chemicals number Qi A5! a, 2 A, 3 A, 4 Ri r2 q2 1-141 1-methyl-5-trifluoromethyl-1H- π ratio tr sit-4-yl CH CH CH CH HH 2,4-di>odor-6-dimethylthiophenyl 1-142 isoxazol-5-yl CH CH CH CH HH 2,4· Dibromo-trifluoromethylsulfenylphenyl 1-143 4-trifluoromethylthiazol-5-yl CH CH CH H H 2,4-dibromo-6-trifluorodecylthiophenyl 1-144 2, 4-Dimercaptothiazol-5-yl CH CH CH CH HH 2,4-dibromo-6-trifluoromethylthiophenyl 1445 2-ethyl-4-methylthiazol-5-yl CH CH CH CH HH 2,4-di>odor-6-difluoromethylthiophenyl 1-146 2-chloro-4-methylthiazol-5-yl CH CH CH CH HH 2,4-dibromotrifluoromethyl Thiophenyl 1-147 3-methyl-isothiazol-5-yl CH CH CH CH H H 2,4-di>Smell-6-di-methylthiophenyl 1-148 3,4-dichloro-isothiazol-5-yl CH CH CH CH HH 2,4-di> - dimethyl thiophenyl 1-149 3-chlorobenzothiazol-2-yl CH CH CH H H 2,4-dibromo-6-trifluoromethyl thiophenyl 1-150 2,2- 1 benzo[1.3]dioxazole-5-yl CH CH CH CH HH 2,4-di>odor-6-dimethylthiophenyl 1-151 2,2-di-benzo-[1.3 Dicarbazole _4-based CH CH CH CH HH 2,4-di > odor-6-disorder methylthiobenyl 1-152 phenyl CF CH CH CH HH 2,4-dibromo-6- Trifluoromethylthiophenyl 1-153 2-phenylphenyl CF CH CH H H 2,4-di>odor-6-dimethylthiophenyl 1-154 4-fluorophenyl CF CH CH CH HH 2,4-di>odor-6-dimethylthiophenyl 1-155 4-chlorophenyl CF CH CH HH 2,4-di>odor-6-dimethylthiophenyl 1-156 2_rat bite-3-yl CF CH CH CH HH 2,4-dibromo-6-trifluoromethylthiophenyl 1457 4-nitrophenyl CF CH CH H H 2,4·2 Bromo-6-trifluoromethylthiophenyl 1-158 4-cyanophenyl CF CH CH:CH HH 2,4-di>odor-6-di-mercaptothiophenyl 1-159 phenyl CH CH :CH ;CE Me )H 2,4-di>Smelly-6-digas sulfhydryl 1-160 2-Chlorophenyl CH:CE [CH [CH ;Mc ^ H 2,4-dibromo-6-trifluoromethylthiophenyl 70 200836629 Table i(9) Compound No. Qi α, 2 A, 3 A ,4 Ri r2 Q2 1-161 4-fluorophenyl CH CH CH Me H 2,4-dibromo-trifluoromethylsulfophenyl 1-162 4-chlorophenyl CH CH CH Me H 2,4 - two > odor-6 - two said methyl hydrazine phenyl 1-163 2-gas.唆-3-yl CH CH CH CH Me H 2,4-dibromo-trifluoromethylthiophenyl 1-164 4-nitrophenyl CH CH CH CH Me H 2,4-dibromo-6- Trifluoromethylthiophenyl 1-165 4-cyanophenyl CH CH CH Me H 2,4-dibromo-6-trifluoromethylthiophenyl 1-166 phenyl CH CH CH CH H Me 2 ,4-dibromo-6-difluoromethylthiophenyl ί-167 2-say phenyl CH CH CH H Me 2,4-dibromo-6-trifluoromethylthiophenyl 1-168 4- Phenyl CH CH CH CH H Me 2,4-dibromo-6-trioxamethylthiophenyl 1-169 4-chlorophenyl CH CH CH CH H Me 2,4-dibromo-6-trifluoro Methylthiophenyl 1-170 2-chloro π ratio -3-yl CH CH CH CH H Me 2,4-dibromo-6-trifluoromethyl thiophenyl 1-171 4-nitrophenyl CH CH CH CH H Me 2,4_二>Smell-6-trifluoromethylthiophenyl 1-172 4-cyanophenyl CH CH CH CH H Me 2,4-dibromo-6-trifluoromethyl Thiophenyl phenyl 1-173 phenyl CH CH CH Me Me 2,4-dibromo-6-trifluoromethylthiophenyl 1-174 2-fluorophenyl CH CH GH CH Me Me 2,4-II >Smelly-6-disorganized methylthiophenyl 1-175 4-decylphenyl CH CH CH Me Me 2,4-dibromo-trifluoromethylsulfophenyl 1-176 4-chlorophenyl CH CH CH CH Me Me 2,4-two> Wu-6-two gas基石瓦phenyl 1-177 2-gas bite-!^-based CH CH CH CH Me Me 2,4-di>odor-6-dimethylthiophenyl 1-178 4-wall phenyl CH CH CH CH Me Me 2,4-di>Smell-6-dimethylthiophenyl 1-179 4-cyanophenyl CH CH CH Me Me 2,4_2>Smelly-6- Difluoromethylthiophenyl 1-180 phenyl CF CH CH H H 2,4-dibromo-6-trifluoromethylsulfinyl 1 phenyl 71 200836629 Table 1 (10) Compound number Qi A5! a , 2 a,3 A,4 Ri r2 Q2 1-181 2-Phenylphenyl CF CH CH H H 2,4-di>Smell-6-di-gas methyl sulphite Yellow phenyl 1-182 4 -fluorophenyl CF CH CH HH 2,4-di>Smell-6-di-gas methyl sulphate phenyl 1-183 4-chlorophenyl CF CH CH H H 2,4-II Odor-6-difluoroimethyl sulfite yellow phenyl 1-184 2-chloropyridin-3-yl CF CH CH H H 2,4-dibromo-6-trifluoromethylsulfinyl benzene 1-185 4-Nitrophenyl CF CH CH CH HH 2,4-di>Smell-6-dimethylmethyl stellite phenyl 1-168 4-nitrophenyl CF CH CH CH HH 2,4-di> odor-6-trimethyl fluorenyl phenyl phthalate 1-187 stupid CH CH CH CH Me H 2,4-di > odor-6-dimethylmethyl stone Styrene phenyl 1-188 2-phenyl phenyl CH CH CH CH H H 2,4-di> odor-6-diqi fluorenyl phenyl phenylphenyl M89 phenyl CH CH CH CH H H 2 ,4-di>Smell-6-di-gas methyl sulphate yellow phenyl 1-190 4-chlorophenyl CH CH CH CH H 2,4-di> odor-6-dimethylmethyl Phosphine phenyl 1-191 2-chloropyridin-3-yl CH CH CH CH Me H 2,4-di > odor-6-di-gas methyl sulphate phenyl 1-192 4 -nitrophenyl CH CH CH CH Me H 2,4-dibromo-6-trifluoromethylsulfinylphenyl 1:193 4-cyanophenyl CH CH CH Me H 2,4-di >Smell-6-two mouse A. Kea phenyl phenyl 1-194 phenyl CH CH CH H Me 2,4-dibromo-6-trifluoromethylsulfinylphenyl 1-195 2-fluorophenyl CH CH CH CH Me 2,4-di>Smell-6-di-mouse methyl sulphate phenyl 1-196 4-fluorophenyl CH CH CH H Me 2,4-II >Smelly-〇-二乱methyl亚绩酸泰本基1-197 4-Chlorophenyl CH CH CH CH H Me ,2,4-二>Smell-$-二鼠曱基亚石黄Phenyl 1-198 2-mouse 0 ratio. Ding-3-yl CH CH CH CH H Me 〉2,4-di>Smell-6-dimethylmethyl sulphate phenyl 1-109 4-nitrophenyl CH CH CH CH H Me 〉 2,4-dibromo-6-trifluoromethylsulfinylphenyl 1-200 4-nitrophenyl CH CH CH H Me ; 2,4-dibromo-6-trifluorodecylsulfin Nonylphenyl 72 200836629 Table 1 (11) Compound No. Qi A, a, 2 A, 3 A, 4 Ri r2 q2 1-201 Phenyl CH CH CH CH Me Me: 2,4-di > -^ gas methyl sulphate phenyl 1-202 2-fluorophenyl CH CH CH Me Me: 2,4-dibromo-6-trifluoromethylsulfinylphenyl 1-202 4 -fluorophenyl CH CH CH Me Me: 2,4-dibromo-6-trifluoromethylsulfinylphenyl 1-242 4-chlorophenyl CH CH CH CH Me Me 2,4-di &gt ; 臭-6-二鼠1曱基亚谱酿基1-205 2-Chlorine^13定-3-基CH CH CH CH Me Me 2,4-二>Smell-6-dioxin Kea stone yellow base phenyl 1-206 4-nitrophenyl CH CH CH CH Me Me 2,4-di > odor-6-di-gas methyl linoleate phenyl 1-207 4- Phenylphenyl CH CH CH CH Me Me 2,4-dibromo-6-trifluorodecylsulfenylphenyl 1-208 Phenyl CF CH CH CH HH 2,4-dibromo-6-trifluoro Methylsulfonyl Phenyl 1-209 2-it phenyl CF CH CH H H 2,4-di> odor-6-disorder fluorenyl yellow phenyl 1-210 4- phenyl phenyl CF CH CH H H 2 4-II>Smell-6-dimethylmethyl tartaric acid phenyl 1-211 4-chlorophenyl CF CH CH H H 2,4-di>Smell-6-dimethylmethyl sallow Phenylphenyl 1-212 2-gas 0-bite-3-yl CF CH CH CH HH 2,4-di>Smell-6-dimethylmethyl fluorenylphenyl 1-261 4-nitrobenzene CF CH CH CH HH 2,4-Dibromo-6-trifluoromethylsulfonylphenyl 1.214 4-cyanophenyl CF CH CH H H 2,4-dibromo-6-trifluoromethylsulfonate Nonylphenyl 1-215 Phenyl CH CH CH CH Me H 2,4-di>Smell-6-^Gasmethylglycolylphenyl 1-216 2-Phenyl CH CH CH CH Me H 2,4-Dibromo-6-trifluorodecylsulfonylphenyl1-217 4-fluorophenyl CH CH CH Me H 2,4-dibromo-6-trifluorodecylsulfonylphenyl 1-218 4-chlorophenyl CH CH CH CH H 2 2,4-di>Smell-6-dioxyl fluorenyl phenyl phenyl 1-219 2-gas hydrazine 17 1-3 base CH CH CH CH :Me Π 2,4-di>Smell-6-dimethylmethyl fluorenylphenyl 1-220 4-Nitrophenyl CH CH CB :CH Me H 2,4·Dibromo_6_ Trifluoromethylsulfonylphenyl 73 200836629 Table 1(12) Compound number Qi a,2 A,3 A,4 Ri r2 q2 1-221 4-cyanophenyl CH CH CH Me H 2,4-di>Smell-6-two mouse Base phenyl phenyl 1-222 phenyl CH CH CH CH H Me 2,4-di > odor-6-dimethylmethyl fluorenyl phenyl 1-223 2-fluorophenyl CH CH CH CH H Me 2,4-di>Smell-6-di-methylmethyl-branched phenyl 1-224 4-fluorophenyl CH CH CH CH 2 2,4-di>odor-6-disorder sill Yellow-brown phenyl 1-225 4-Phenylphenyl CH CH CH CH H 2,4-di>Smell-6-dioxyl fluorite yellow phenyl 1-226 2-gas ratio 0- 3-based CH CH CH CH H Me 2,4-dibromo-6-trifluoromethylsulfonylphenyl 1-227 4-nitrophenyl CH CH CH CH Π Me 2,4-di > -6_二气曱石石黄-based phenyl 1-228 4-cyanophenyl CH CH CH CH H Me 2,4-di> odor-6-diqi fluorenyl phenyl phenyl 1-229 benzene CH CH CH CH Me Me 2,4·二》臭-6-二乱乱methyl石黄毛基1-230 2-fluorophenyl CH CH CH CH Me Me 2,4-二> 6-two squirrel basestone yellow phenyl 1-231 4-fluorophenyl CH CH CH Me Me 2,4-di, / odor · 6-difluoromethyl zeolitic phenyl 1-232 4 -gas Phenyl CH CH CH CH Me Me 2,4-dibromo-6-trifluoromethylsulfonylphenyl 1-233 2-gas oxime 12 -3-yl CH CH CH CH Me Me 2,4-II Bromo-6-trifluorodecylsulfonylphenyl 1-234 4-nitrophenyl CH CH CH CH Me Me 2,4-di>odor-6-dioxyl fluorenyl phenyl 1- 235 4-cyanophenyl CH CH CH CH Me Me 2,4-di>Smell-6-disintegrated methyl stone yellow base base 1-263 phenyl CF CH CH CH HH 2,4-di> Odor-〇-di-gas methyl saponin phenyl 1-273 2-fluorophenyl CF CH CH CH HH 2,4-di> odor-6-dimur 曱 亚 亚 黄 黄 苯基 1 -238 4-fluorophenyl CF CH CH CH HH 2,4-di>odor-6-diqi fluorene phenyl phenyl 1-2-3 4-chlorophenyl CF CH ;CE CH :HH 2 ,4-di>Smell-6-trimethylsulfide yellow phenylphenyl 1-240 2-gas oxime 11 -3--3-CF CH CH CH :HH 2,4-di> - Di-gas methyl sulphate yellow phenyl 74 200836629 Table 1 (13) Chemical preparation number Qi a, 2 A, 3 A, 4 Ri r2 Q2 1-241 4-nitrophenyl CF CH CH CH HH 2,4-di>Smell-6-di-gas methyl garnet yellow phenyl 1-242 4-cyanophenyl CF CH CH H H 2,4-di>Smell-6-di Kia Phytophenyl phenyl 1-243 phenyl CH CH CH CH Me H 2,4-di -6-Santon methyl linoleic acid phenyl 1-244 2-fluorophenyl CH CH CH CH Me H 2,4-di>Smell-6-diqi fluorenyl sulphate phenyl 1-245 4-1 phenyl CH CH CH Me H 2,4-di>Smell-6-dual mouse Methyl sulphate phenyl 1-246 4-chlorophenyl CH CH CH CH Me H 2,4-dibromo-6-trifluoromethylsulfinylphenyl 1-247 2-chloro ratio ^定-3-基CH CH CH CH Me H 2,4-二>Smell-6-dimurium quinone phenylphenyl 1-248 4-nitrophenyl CH CH CH Me H 2, 4-dibromo-6-trifluoromethylsulfinylphenyl 1-245 4-oxylphenyl CH CH CH Me H 2,4-dibromo-6-trifluorodecylsulfinylbenzene 1-250 phenyl CH CH CH CH H 2 2,4-di> odor-6-diqi fluorenyl phenyl phenyl 1-251 2-fluorophenyl CH CH CH H Me 2, 4-Dibromo-6-trifluoromethylsulfinylphenyl 1-252 4-fluorophenyl CH CH CH H Me 2,4-dibromo-6-trifluoromethylsulfinylphenyl 1-253 4-chlorophenyl CH CH CH CH H Me 2,4-di>Smell-6-two said methyl slate yellow phenyl phenyl 1-254 2 · gas 0 ratio °-3-yl CH CH CH CH H Me : 2,4-dibromo-6-three Fluoromethylsulfinylphenyl 1-255 4-nitrophenyl CH CH CH H Me ; 2,4-dibromo-6-trifluoromethylsulfinylphenyl 1-256 4-cyano Phenylphenyl CH CH CH CH ΊΓ X w Me ;z,4-di>odor-6-diqimethyl yttrium yellow aryl base 1-257 phenyl CH CH CH CH :Me Me 丨2,4- Dibromo-6-trifluoromethylsulfinylphenyl 1-258 2-fluorophenyl CH CH CH : Me Me ; 2,4-dibromo-6-trifluoromethylsulfinylphenyl 1-259 4-fluorophenyl CH CH CH CE [Me ; 2,4-dibromo-6-trifluoromethylsulfinylphenyl 1-260 | 4-chlorophenyl CH CH CE [CH [Me 2,4-dibromo-6-trifluoromethylsulfinylphenyl 75 200836629 Table 1 (14) Chemical practice number Qi A' a, 2 a, 3 A'4 Ri r2 Q2 1-261 2-吼σ定-3-基CH CH CH CH Me Me 2 头二漠+Trifluoromethyl hydrazinyl 1-262 4·Nitrophenyl CH CH CH Me Me 2, Φ Dibromo + Trifluoromethanesulfinylphenyl phenyl 1-263 4·^»-based CH CH CH CH Me Me 2, Φ dibromo + trifluoromethyl succinyl phenyl 1-246 stupid CH CH CH CH HH 4. Bromine "2-chloro-trifluoromethylthiophenyl 1-265 phenyl CH CH CH H H 2 - Molycol Chlorine Trifluoromethylthiophenyl 1-266 phenyl CH CH CH CH HH 2-chloro ice (4> cyanophenyl trifluoromethylphenyl 1-267 phenyl CH CH CH H H 2 2 chloro 4 < 2-trifluoromethylphenyl >6 «trifluoromethylthiophenyl 1-268 phenyl CH CH CH H H 2 2,6·dimethyl ice (2-prepared 1M-trifluoro 4-trifluorodecylethyl)phenyl 1- 269 2-fluorophenyl CH CH CH CH HH 2,6· dimethyl 4(2-bromotritrt·trifluoromethylethyl)phenyl 1-270 fluorophenyl phenyl CH CH CH H H 2,6 - Dimethyl basic (2-bromo-1 fluorene 2-tris 4-trifluoromethylethyl)phenyl 1-271 'chlorophenyl CH CH CH CH HH 2,6-dimercapto 4<2-bromotrifluoro -1-trifluoromethylethyl)phenyl 1-172 2-Chloro-Butyl-3-yl CH CH CH CH HH 2,6-Dimethyldi-l-difluoro-methylethyl Phenyl 1-273 4 · Nit CH CH CH CH HH 2,6* Dimercapto 4<2-bromotrifluoro 4-trifluoromethylethyl)phenyl 1-274-based CH CH CH CH HH 2, 6·Dimethyl 4<2-bromo-1Λ2-triseo-1-trifluoromethylethyl)phenyl 1-275 phenyl CF CH CH CH HH 2,6·dimethyl 4-(2- Difluoro-4-difluoro(ethyl)phenyl)1-276 2-fluorophenyl CF CH CH HH 2,6>Dimethyl winter (2-bromo-Ιβ-tri-gas rl-trifluoromethyl Phenyl 1-27 7 fluorinated phenyl CF CH CH CH HH 2,6»dimethyl basic (2-bromotrifluoro 4-trifluoromethylethyl)phenyl 1-278 'chlorophenyl CF CH CH ce :HH 2,6&gt Diterpene-based (2-bromo-4-ditrifluoro-1-trifluoromethylethyl 1)phenyl 1-279 2-merole, 3-yl: CF CH OH CH :HH 2, 6 «二曱基车(2-Bromo 4M-trifluoro-1-trifluoromethylethyl)phenyl 1-280 "Shaws CF CH : CH : CH [HH 2,6 · Dimercapto 1 ( 2-Bromo 4M-trifluoro-rl-trifluoromethyle-phenylphenyl 76 200836629 Table 1 (15) ^____—I don't know how to number Qi K' a,2 A, a,4 Ri r2 1-281 φ Secret Stupid CF CH CH CH HH 1-282 Stupid CH CH CH CH Me H 2,6·Dimethyl 4<2-Mool 1-283 2-Fluoro Stable CH CH CH CH Me H 2,6·II曱基顿(10) 1-284 丰氟基基 CH CH CH CH Me H 2,6-dimethyl "4<2善0三^^®^^^ 1-285 This chlorinated CH CH CH CH Me H 2 winter - sulfhydryl 4 (2 · bromine like diethylene light complete 1-286 2-chloro% π 士士 a CH CH CH CH Me H 2,6-dimethyl car (2-^-0 trifluoro- 1-Difluoromethylethyl) Benzo 1-287 nitro-nitro stupyl CH CH CH CH Me H Noisy bismuth car (2-bromo-1 with trifluoro 4-trifluoromethylethyl) phenyl 1-288 this II基笨基 CH CH CH CH Me H 2,6·—曱基4-(2-Bromomethystamine II-89 Stupid CH CH CH CH H Me 2,6·Dimethyl car (2- Bromine "Ιβ-Trifluorostrip three gas reeds see 1-290 2-fluorophenyl CH CH CH CH H Me 2,6-dimethylbromotrifluoro 4-: defeated Acoustic 1-291 car fluorophenyl CH CH CH CH H Me 2,6·-methyl 4»(2-bromodifluoro 4-:fluoroantimony, 7 1-292 1-293 lichlorophenyl CH CH CH CH H Me ------&gt ;Ss 2, Fu:? Base"HZ-'/lrIM-two gas, 2-chloro to 3·yl • CH CH CH CH H 2,6~ monomethyl-4-(2-bromide) | 1-294 Phenyl phenyl CH CH : CH CH H Me ---~~ phenyl 丨 2,6 · triterpene winter (four) like three sets of μ : t surgery emblem 1-295 wood fl base stupid CH CH CH CH H Me 〉2,6·>-Methyl*4·(2_Bromo-1^2^2-三氤二备w上上u 77 200836629 Table 1(16) No. Qi A?! a, 2 A, 3 A'4 Ri r2 q2 1-296 Phenyl CH CH CH CH Me Me 2,6~Dimethyl 4<2-Bromo-1 Total Trifluoro-Winter Trifluorodecyl Ethyl) Clumpy 1-129 2- Fluorophenyl CH CH CH CH Me Me 2,6> Dimercapto 4<2-Bromotrifluorosuccinylethylethyl)Molyl 1-198 4»Fluorophenyl CH CH CH Me Me 2,6· Dimercapto 4<2-bromo 4, tritrifluorodecylethyl) Molybdenum 1-199 chlorophenyl phenyl CH CH CH CH Me Me 6: Dimercapto- bromo·1 bis trifluorotrifluoro Methyl ethyl) methane 1-300 2-air port tb7 each group CH CH CH CH Me Me base 4 < 2 · bromine 4 total trifluoro-1-trifluoromethylidene ethyl) methane 1-301 Φ nitrate Phenylphenyl CH CH CH Me Me 2,6^曱 溴 溴 〇 敦 敦 ΐ ΐ 曱 曱 曱 1-3 1-3 1-3 1-3 1-3 1-3 1-3 1-3 1-3 1-3 1-3 1-3 1-3 1-3 1-3 1-3 1-3 1-3 1-3 1-3 1-3 1-3 2,6· dimethyl car (2·Bromo 4 and trifluoro-μtrifluoromethylethyl) loaded with 1-103 phenyl CH CH CH H H 6 · bromo-8-heptafluoroisopropyl quinine 1-304 2-fluorophenyl CH CH CH H H 6 · -8 - heptafluoroisopropyl propyl -5 - yl 1-305 4 · succinyl phenyl CH CH CH CH HH —----- 6 · bromine each seven isopropyl lysine-5-yl 1-306 phenyl CH CH CH CH HH 2,6» dimethyl neighbor 1 and 2 - 3 -1 -trifluoromethyl B 1-307 phenyl CH CH CH CH HH --------- 2,6 «dichlorotrifluoro 4-trifluoromethyl ethoxy oxy 1-308 2_ like phenyl CH CH CH H H 2 ,6·dichlorotrifluoro-1-trifluorodecyl ethoxybenzene Benzene 1-109 phenyl CH CH CH CH HH 5,7-dibromo-2^2,3,3-tetrad-1,4 ·Benzene two drink according to ', 莘 1-310 2-fluorophenyl CH CH CH H H 5,7-dibromo-2233-four Dun-1,4« benzodiabene married base 1-311 car fluoride Phenyl CH CH CH CH HH 5,7-II--2 and 3,3_tetrafluoro 4, Benzo benzoquinone 芊1-312 nitrophenyl phenyl CH CH CH H H 5,7-II Bromo-2233-四敦-1,4"Benzene II, plucking people, etc. 1-313 Phenyl CH CH CH [CH HH 5,7-二漠-2^2-二气1,3·Benzene 2 Sit ▲ Raspberry 1-314 2-gas benzene CH CH CH [CE HH 2,6·dichloro·Φ trifluoromethyl phenyl 1-35 2,6-di-phenylphenyl CH CH OH [CH [HH 2,6-dichloro-t-trifluoromethyl] Base—---- ——.^ 78 200836629 Table 1 (17)

Chemical number Qi α,2 A,3 A,4 Ri r2 q2 1-316 Phenyl CH CH CH CH HH 2,4-Dibromo-6-trifluoromethylphenyl 1-317 4_Ga-3-Shi Xiaoji Phenyl CH CH CH CH HH 2,4-dibromo-6-trifluorodecylphenyl 1-318 5-fluoro-2-mercaptophenyl CH CH CH CH HH 2,4-dibromo-6-di Fluorodecylphenyl 1-319 2-Ga-6-Ethyl CH CH CH CH HH 2,4-Dibromo-6-trifluoromethylphenyl 1-320 4-Nitrophenyl CH CH CH CH HH 2,4-di>Smell-6-dispelenylphenyl 1-321 4-phenylazophenyl CH CH CH CH HH 2,4-dibromo-6-trifluoromethylphenyl 1 -322 2-(4-Trifluorodecylphenyl)phenyl CH CH CH HH 2,4·dibromo-6-trifluoromethylphenyl 1-232 4-methoxycarbonylphenyl CH CH CH CH HH 2,4-di--6-difluoromethylphenyl 1-324 2,6-dimethoxyphenyl CH CH CH CH HH 2,4-dibromo-6-trifluoromethylphenyl 1 -325 吼嘻-2-yl-CH CH CH CH HH 2,4-dibromo-6-trifluoromethylphenyl 1-326 5-(phenylethyl carbyl) succinyl-2-yl CH CH CH CH HH 2,4-di>Smell-6-di-p-decylphenyl 1-327 5-(phenylethyl fast keto ratio -3--3-CH CH CH CH HH 2,4-dibromo -6-trifluoromethylphenyl 1-328 4-pyridyl CH CH CH CH HH 2,4-dibromo-trifluoromethylphenyl 1-329 2,4-digas-3-σ ratio σ-based CH CH CH CH HH 2,4-di > odor-6-three Fluoromethylphenyl 1-330 3-ethynyl CH CH CH CH HH 2,4-dibromo-6-trifluoromethylphenyl 1-331 2-methoxyphenyl CH CH CH HH 2,4 -二>Smell-6-dimethylphenyl 1-332 2-phenoxyphenyl CH CH CH HH 2,4-dibromo-6-trifluoromethylphenyl 1-333 2-indole琳基 CH CH CH CH HH 2,4-dibromo-6-trifluoromethylphenyl 1-334 4-quino-based CH CH CH CH HH 2,4-di> odor-6-difluorodecyl Phenyl 1-335 2-phenylindolin-4-yl CH: CH CH CH :HH 2,4-dibromo-6·trifluoromethylphenyl 79 200836629

Table 1 (18) The details are not numbered Qi Α5! α,2 · A53 A,4 Ri r2 q2 1-336 Qinji CH CH i CH CH HH 2,4-Dibromo-6-trifluoromethylphenyl 1 -337 蒽冬基 CH CH丨CH CH HH 2,4-dibromo-trifluoromethylphenyl 1-38 σ-decyl-9-yl CH CH- CH CH HH 2,4-di > odor-6- Difluoromethylphenyl 1-39 phenyl CH CH CH CH HH 2-bromo-4,6-bis(trifluoromethyl)phenyl 1-340 phenyl CH CH CH H H 2,4-double (three Fluorodecyl)phenyl 1-341 2-cyanophenyl CH CH CH HH 2,4-bis(tri-L)phenyl 1-342 3,5-diphenylphenyl CH CH CH CH HH 2,4-bis(trifluoromethyl)phenyl 1-343 2,6-diphenylphenyl CH CH CH H H 2,4-bis(trimethyl)phenyl 1-344 2,3,4- Trifluorophenyl CH CH CH H H 2,4-bis(trimethylene)phenyl 1-345 4-chlorophenyl CH CH CH CH HH 2,4-bis(trimethyl)phenyl 1- 346 2,4-Dichlorophenyl CH CH CH H H 2 2,4-bis(trimethyl)phenyl 1-347 4,5-difluoroτ2-nitrophenyl CH CH CH HH 2,4 - bis(trimethyl)phenyl 1-348 3-1-2-methylphenyl CH CH CH CH Π 2,4-bis(trifluoromethyl)phenyl 1-349 4-methylbenzene CH CH CH CH HH 2,4-bis(trifluoromethyl) 1-350 4-ethylphenyl CH CH CH H H 2,4-bis(trimethyl)phenyl 1-351 3-decyloxyphenyl CH CH CH CH HH 2,4-double (three Gas methyl)phenyl 1-352 4-decyloxyphenyl CH CH CH :CH HH 2,4·bis(trifluoromethyl)phenyl 1-353 354,5-trimethoxyphenyl CH CH CH [CH Π H 2,4-bis(trifluoromethyl)phenyl 1-354 1-naphthyl CH CH CE [CH :HH 2,4-bis(trifluoromethyl)phenyl 1-355 2-naphthalene CH CH CH [CH;HH 2,4-bis(trimethylsulfonyl)phenyl 80 200836629 Table 1 (19) Fossil number Qi α, 2 AV A% Ri r2 Q2 1-356 5-Ga-2-ϋ Benzenyl CH CH CH CH HH 2,4-bis(trifluoromethyl)phenyl 1-357 2-gas-3·11 specific hydrazide CH CH CHi CH HH 2,4-bis(trifluoromethyl) Phenyl 1-358 6-methyl-2-11 ratio sigma CH CH CH CH HH 2,4-bis(trimethyl)phenyl ' 1-359 5- gas-2-fluorene 12-based CH CH CH CH HH 2,4-bis(trifluoromethyl)phenyl 1-560 6-light-2-yl CH CH CH CH HH 2,4-bis(trifluoromethyl)phenyl 1-361 5 - 曱 base - ° ratio. Well-2-yl CH CH CH CH HH 2,4_bis(trifluoromethyl)phenyl 1-362 ϋ比耕-基CH CH CH CH HH 2,4-bis(tri-l-methyl) Phenyl 1-163 5-methyl-2-thienyl CH CH CH CH HH 2,4-bis(trimethyl)phenyl 1-364 3-methyl-2-thienyl CH CH CH CH HH 2 ,4-bis(trifluoromethyl)phenyl 1-365 phenyl CH CH CH HH 2,5-bis(trifluoromethyl)phenyl 1-366 phenyl CH CH CH HH 2-chloro·4 ,6-bis(trifluoromethyl)phenyl 1-367 2,6-difluorophenyl CH CH CH HH 2-chloro-4,6-bis(trimethyl)phenyl 1-368 4- Nitrophenyl CH CH CH CH HH 2-chloro-4,6-bis(trifluoromethyl)phenyl 1-369 phenyl CH CH CH CH H Π 2-bromoindole-4-(trifluoromethane Sulfomethoxy)phenyl 1-370 2-fluorophenyl CH CH CH HH 2_bromo-6-fluorenyl winter (trifluorodecanesulfooxy)phenyl 1-371 phenyl CH CH CH CH HH 2-Chloro-6-mercapto-4-(dioxamethoate xanthyloxy)phenyl 1-327 phenyl CH CH CH CE [HH 2_methyl_4-(trifluoromethanesulfonyloxy) Phenyl 1-373 phenyl CH CE CH CB [HH 4-(seven isopropyl)-2-indenyl 1-734 2-fluorophenyl CH CH : CH CE HH 4-(heptafluoroiso) Propyl)-2-methylnaphthyl 1-375 Group 1 CH CB: CH: ct H H 7- heptafluoroisopropyl two Yun-inden-4-yl 81

ItMj No. Qi AV A, 4: Ri r2 q2 1-376 Phenyl CH CH<CH CH HH 2,6-Dichloro-4-pentafluorosulfanylphenyl 1-377 Phenyl CH CH (CH CH HH 4 -(3,4-difluorophenyl)-2,6-dimethylphenyl 1-378 phenyl CH CH丨CH CH HH 4-(4-Ga-3-methylphenyl)-2,6 -Dimethylphenyl 1-379 phenyl CH CH CH HH 4-(N--3-yl)-2,6-dimethylphenyl 1-380 2-chlorophenyl CH CH CH CH HH 2 ,6-dimercapto-4-(° plug-in-2_yl)phenyl^ 1-381 2-chlorophenyl CH CH CH CH HH 2,6-dimethyl-4-(zesophene- 3-yl)phenyl 1-832 phenyl CH CH CH H H 2,6-di > odor-4-5 succinylphenyl 1-383 phenyl CH CH CH CH HH 4-cyclohexyl phenyl 1- 384 phenyl CH CH CH H H 2,6-dimercapto-4-(pentafluoropropenyl)phenyl 1-385 phenyl CH CH CH CH HH 4-(heptafluorobutylidene)-2,6-di Methylphenyl 1-386 phenyl CH CH CH H H 2,6-dimercapto-4-(2,2,2-diox-1-dimethylmethylethyl)phenyl 1-387 phenyl CH CH CH CH HH 2->Smelly-6-(2,2,2-diox-1-dimethylolethoxy) ° ratio -3-yl 1-388 phenyl CH CH CH CH HH 2,2,3,3,4,4,4-heptafluorobutyl 1-389 phenyl CH CH CH CH HH 2,2,3,3,3-pentafluoropropyl 1-390 phenyl CH CH CH [CH :HH 2,4,6-di-di--3-decyl propylthiophenyl 1-391 2-gas倍-3-基CH CH CH [CH ;HH 2,4,6-di> odor-3-septyl propyl phenyl 1-352 2- phenyl CH CH CH [CH LHH 2, 4,6_2>Smelly-3-heptafluorot-propylthiophenyl-1-93 2- disordered phenyl CH CH :CE [CH [HH 4-dimethylthiophenyl 1,394 2-fluorobenzene CH;CH:CE [CE [HH 4-trifluoromethylsulfonylphenyl 1-395 phenyl CH [CH iCE ICE [HH 4-heptylpropyl phenyl phenyl 200836629 Table 1 (20) 82 200836629 Table 1 (21) No. Qi A5! a'2 AA,4 Ri r2 _________—^^— ___q2 1-396 Stupid CH CH CH CH HH 1-397 Stupid CH CH CH CH HH ----- Team, , 1 Feng Feng ------ ---- 4 * seven it C a stone n ψ 甘 1-3 1-3 1-3 _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ Heptafluoropropylsulfonyl 1 is 1-99 2-fluoro-p-CH CH CH CH HH — --------------thio-2-methyl stupid 1-400 phenyl CH CH CH CH HH 4-methyl-neutral trifluoro-μ-trifluoromethyl seven-nose mouth ratio -3-yl 1401 2 invites stupid CH CH CH CH HH Methyl _ 乙 口 咬 -3- 基 基 基 1402 2-fluorophenyl CH CH CH H H 2 2 2 Ά trifluoro-1-trifluoromethyl 乙 细 咖 1- 1- 1- 1- 1- 1- 1- 1- 1- 1- 1- 1- 1- 1- 1- 1- 1- 1- 1- 1- 1- 1- 1- 1- 1- 1- 1- 1- 1- 1- 1- 1- 1- 1- 1- 1- 1- 1- 1- 1- 1- 1- 1- HH 4 «{2 again 2-trifluoro-1·(trifluoromethyl) ethoxylated oxime 1404 2-fluorophenyl CH CH CH CH H three gas-1 « (trifluoromethyl thiophene b Ethyl} each group 1-405 phenyl CH CH CH H H 2, the present dibromo trifluoromethoxy stupid 1-406 2-fluorophenyl CH CH CH CH HH J------ -1~ ----- 2+夂Bromo-6»Trifluoromethoxy Appease 1 L 4-Shischyl Phenyl CH CH CH CH HH 2,4^漠》6^Fluoromethoxyphenyl i- 408 phenyl CH CH CH CH HH Heart bromine-6 «trifluoromethoxyphenyl 1 genus 9 2, the present difluorophenyl CH CH CH H H 2 2, Φ dibromocarditrifluoromethane, a certain 1410 phenyl CH CH CH CH HH 2,4·monobromo-6·{heptafluoropropylsulfide)phenyl 1411 2-1 phenyl CH CH CH HH 2, Φ dibromo(pentafluoropropyl)phenyl 1412丰nitrophenyl CH CH CH CH HH 2 piped dibromo (heptafluoropropyl thio) phenyl 1-413 phenyl CH CH CH CH HH 2,4 «dibromo 6·{nonafluorobutyl sulphate; Phenyl 1414 2-fluorophenyl CH CH CH • CH HH 2-bromo 4» chloro 4 trifluoromethyl Phenyl 1415 phenyl CH CH CH : CH HH 2-bromyl chloride-6 «trifluoromethylphenyl 83 200836629 Table 1 (22) No. Qi A5! a, 2 A, 3 AV Ri r2 q2 1-416 2 -fluorophenyl ΟΠ CH CH CH CH HH 2-bromo-6-chloro-4-trifluoromethylphenyl 1- phenyl phenyl CH CH CH HH 4-> odor-2-chloro-6-difluoroanthr Phenylphenyl 1-418 2,6-diphenylphenyl CH CH CH CH HH 4->Smelly-2-gas-6-dimethylphenyl 1-419 Phenyl CH CH CH CH HH 2-&gt ; stinky 4-1-6-trimethylphenylphenyl 1-420 phenyl CH CH CH CH HH 4-fluoro-6-trifluoromethylphenyl 1-421 2-Ethyl CH CH CH CH HH 4-heptafluoroi-isopropyl-2-mercaptophenyl 1-522 phenyl CH CH CH HH 2-t-butyl-4-heptafluoroisopropylphenyl 1-423 phenyl CH CH CH CH HH 2-murine-4-heven isopropylphenyl 1-424 2-fluorophenyl CH CH CH CH HH 4-heptafluoroisopropylphenyl 1-245 phenyl CH CH CH H H 2- Dioscorea-4-pyrrolidylphenyl 1-426 4-nitrophenyl CH CH CH CH HH 2-methyl sulphate yellow saponin-4-seven isopropyl phenyl 1-427 benzene CH CH CH CH HH 2,6-Dibromo-4-trifluoromethylphenyl 1-288 2-fluorophenyl CH CH CH CH HH 2,6-II- Fluoro[methylphenyl] 1-429 2,6-diphenylphenyl CH CH CH CH HH 2,6-di>odor-4-difluoro-1-methylphenyl 1-430 phenyl CH CH CH CH HH 2,6-Dichloro-4-(2,2,3,3,3-pentafluoropropoxy)phenyl 1-341 2-fluorophenyl CH CH CH CH HH 2,6-dichloro-4- (2,2,3,3,3-pentafluoropropoxy)phenyl 1-432 phenyl CH CH CH HH 2-methyl·4-(2,2-trifluoroethoxy)phenyl 1 -433 2-Chloropurine -3--3-CH CH CH CH HH 2,6-Dichloro-4-(2,2,3,3,3-pentafluoropropoxy)phenyl 1-344 phenyl CH CH :CH CH HH 2,6-Dimethyl-4-(2-Gas-2,2-disorder-1_(chlorodifluoromethyl)-1-hydroxyethyl)phenyl 1-435 phenyl CH CH [CH CH HH 2,6-Dimethyl-4-(2,2,2-difluoro-1-difluoromethyl-1-methoxy)phenyl 84 200836629 Table 1 (23) Qi A, A, 2 A, 3 A, 4 Ri r2 q2 1-436 2-Phenylphenyl CH CH CH CH HH 2,6-Dimercapto-4-(2,2,2-trifluoro-1- Trifluoromethyl methoxy phenyl) 1-437 phenyl CH CH CH H H 2,6-dichloro-4-trifluoromethoxyphenyl 1-438 phenyl CH CH CH H H 2- Base-4-difluoromethoxyphenyl 1-439 stupyl CH CH CH CH HH 5-stone succinyl ratio butyl-2-yl 1-440 phenyl CH CH CH CH H H 5-Chloroisridin-2-yl 1-441 Phenyl CH CH CH CH H H 4-Methyl-6-(seven isopropyl)-. °定-3-基1-442 phenyl CH CH CH CH HH 3-气-5-二气曱 σ ratio σ定-·2-yl 1-443 phenyl CH CH CH H H 5-7 Isopropyl-2·methoxy-methoxy-4-methyl σ- thiophene-3-yl 1-444 2-phenylphenyl CH CH CH H H 5-heptafluoroisopropyl-2-methoxycarbonyl Thiophen-3-yl 1-4545 phenyl CH CH CH HH 2-> odor-6-gas-4-methyl σ ratio sigma-3-yl 1-446 phenyl CH CH CH H H 2 6-Dimethyl-4-trifluoromethylphenyl 1-475 2-fluorophenyl CH CH CH H H 2,6-Dimethyl-4-dimethylmethylphenyl 1-448 phenyl CH CH CH CH HH 4-trifluoromethylbenzyl 1-449 phenyl CH CH CH CH HH 3-trifluoromethylbenzyl 1-450 phenyl CH CH CH CH H TT 2-trifluorodecyl benzyl 1- 451 phenyl CH CH CH CH HH 4-wall base group 1-452 phenyl CH CH CH CH HH 3,5-bis(trifluoromethyl) group 1-453 phenyl CH CH CH H H 4- gas -2,6-Dimethylphenyl 1-454 phenyl CH CH CH CH HH 4- Desert-2,6-Dimethylphenyl 1-455 phenyl CH CH CH CH :HH 4-A-2, 6-Dimethylphenyl 85 200836629 Table 1 (24) Compound number Qi A9! a, 2 A, 3 A, 4 Ri: Q2 1-456 2,6-di-phenyl phenyl CH CH C H CH HH 4-Moth-2,6-Dimethylphenyl 1-457 phenyl CH CH CH H H 4-chloro-2-difluoropyridylphenyl 1-458 phenyl CH CH CH CH HH 2 -Chloro-6-difluoromethylphenyl 1-245 phenyl CH CH CH HH 4-E-2-dimethylphenyl 1-450 Phenyl CH CH CH CH HH 2-Galy-4-Moth -6-methylphenyl 1-461 phenyl CH CH CH CH HH 2,6-dimethylphenyl 1-462 phenyl CH CH CH CH HH 4-bromo-2-indolyl-5-trifluoromethyl -2H-pyrazol-3-yl 1-463 phenyl CH CH CH H H 2,3,5,6-tetrafluoro-4-trifluorodecylphenyl 1-424 phenyl CH CH CH CH HH 2 ,3,4,5,6-pentafluorophenyl 1-455 2-fluorophenyl CH CH CH H H 2,3,4-trifluorophenyl 1-446 2-Phenyl CH CH CH CH HH 4 -trifluoromethylphenyl 1-467 2-plex phenyl CH CH CH HH 2-> odor-4-dimethylphenyl 1-68 phenyl CH CH CH HH 2-bromo-6- Chloro-4-trifluoromethylphenyl 1-469 2-phenylphenyl CH CH CH GH HH 2-trifluoromethylphenyl 1-470 phenyl CH CH CH CH HH 2,4-dichloro-6- Trifluoromethylphenyl 1-471 phenyl CH /^TT CH CH HH 2->odor 4-isopropyl-6-dimethylphenyl 1-452 2-fluorophenyl CH CH CH CH HH 2-bromo-4-isopropyl-6-three Methylphenyl 1-473 phenyl CH CH CH H H 4-(heptafluoroisopropylcarbonyl)phenyl 1-444 phenyl CH CH CH CH HH 2-mercapto-4-nitrophenyl 1-475 Phenyl CH CH CH CH HH 2,4-dichlorophenyl 86 200836629 Table 1 (25) Compound number Qi a,2 A,3 A,4 Ri r2 Q2 1-476 Phenyl CH丨CH CH CH HH 3- Moth-5-renylphenyl 1-475 phenyl CH CH CH H H 2 2,6-dimethyl-4-nitrophenyl 1-478 phenyl CH CH CH CH HH 5-stone succinyl-2-. Σσ定基1-479 Phenyl CH CH CH CH HH 1-480 Phenyl CH CH CH CH HH 4-Dicylene Diyl Oxo-2-Mercaptophenyl 1-481 Phenyl CH CH CH CH HH 4 -benzimidyloxy-2-methylphenyl 1-482 phenyl CH CH CH HH 4-benzylideneoxy-6-chloro-2-methylphenyl 1-843 phenyl CH CH CH CH HH 6-gas-4-carbyl-2-mercaptophenyl 1-484 phenyl CH CH CH HH 2-> odor-4-3⁄4 -6-nonylphenyl 1-485 phenyl CH CH CH CH HH 2-Moline-6-Methyl-4-(p-toluene)-Phenyl 1-486 Phenyl CH CH CH CH Me H 2,6-II>Smelly-4-(°Bilo定定-1 - slow base) phenyl 1-287 phenyl CH CH CH CH Me H 2,6-di > odor-4-ethoxy phenyl phenyl 1-488 phenyl CH CH CH H H 2 6-Dichloro-4-(2,5-di-oxy-3,3,4,4-tetrafluoroanthracene-1-yl)phenyl 1-089 phenyl CH CH CH HH 2, 6-diqi-4-(2,5-di-l-butyl-based decyl-1-yl)phenyl 1-490 phenyl CH CH CH CH HH 2,6-dichloro-4-(1, 3-tertiaryoxyisoindoline-2-yl)phenyl 1-451 phenyl CH CH CH HH benzothiazol-2-yl 1-492 phenyl CH CH [CH CH HH benzothiazole-6 -Base 1-493 phenyl CH CH [CH CH HH 6-Chlorobenzothiazol-2-yl 1-494 phenyl CH CH [CH CH HH 5,6-dimethylbenzothiazole-2 yl 1-495 phenyl CH CK [CH CH HH 6-methoxy Benzothiazol-2-yl 87 200836629 Table 1 (26) Compound No. Qi a,2 A,3 A,4 Ri r2 q2 1-496 Phenyl CH CH CH CH HH 5-Chlorobenzoxazole-2- Base 1-197 phenyl CH CH CH H H 4 4,6-dibromo-3H-benzo[d]imidazol-5-yl-4-98 2-gas ratio 0 -3--3-CH CH CH CH HH 4 ,6-Dibromo-3H-benzo[d]imidazol-5-yl-4-99 phenyl CH CH CH CH HH 唉琳-8-yl 1-500 phenyl CH CH CH CH HH 喧Base 1-501 phenyl CH CH CH CH HH isoindolin-1-yl 1-502 phenyl CH CH CH CH HH 4-phenylazobenyl 1-503 phenyl CH CH GH HH 4-phenyl Thiazol-2-yl 1-504 phenyl CH CH CH CH HH 3-methylisothiazol-5-yl 1-505 phenyl CH CH CH CH HH 5-phenyl-2H-pyrazole-3-yl 1- 506 phenyl CH CH CH CH HH 苐-2-yl 1-507 phenyl CH CH CH H H 9 9-side oxime-2-yl 1-508 phenyl CH CH CH CH HH -509 phenyl CH CH CH CH HH adamantane-2-yl 1-510 phenyl CH CH CH CH HH 3H-isoindole-1-ylindole-5苯基 phenyl CH CH CH CH i H 2,6-dimethylpyrimidin-4-yl 1-512 phenyl CH CH CH HH 3,4-dicyanophenyl 1-513 phenyl CH CH CH CH HH 5-methylsulfur-1H-[1,2,4]triazol-3yl-1-part phenyl CH CH CH CH Π H 5- Desert-2-yl 1-515 Phenyl CH CH CH CH HH 4-methylthiazole-2-yl 88 200836629

89 200836629 Table 1 (28) Chemical grain number Qi Α' A, A, 3 A, 4 Ri r2 q2 1-536 2-fluorophenyl CH CH CH H H 2 2,6-II -4-propyl benzene 1-537 2-Phenylphenyl CH CH CH CH HH 2,6-Dibromopropylsulfonylphenyl 1-538 2-fluorophenyl CH CH CH CH HH 2,6-Dibromo-4-propenyl Isosulfonylphenyl 1-549 2-fluoro^phenyl CH CH CH H H 2,6-di,/odor 4-phenylthiophenyl 1-540 phenyl CH CH CH H H 2,6 -二>odor-4-phenylthiobenyl 1_541 phenyl CH CH CH CH HH 2,6-dibromo-4-(4-trifluoromethylphenylmethylsulfate)phenyl 1-542 2- Fluorophenyl CH CH CH CH HH 2,6-di>Smelly-4-(4-dimethylphenylmethylsulfide)phenyl 1-543 2-Chloro 0 to °-3-yl CH CH CH CH HH 2,6-II-4-(4-trifluorodecyl-phenylthio)phenyl 1-544 4-nitrophenyl CH CH CH CH HH 2,6-dibromo-4- (4-trifluoromethylphenylmethylsulfanyl)phenyl 1-545 4-phenylphenyl CH CH CH CH HH 2,6-di >Smelly-4-(4-Tritonmethylphenylmethyl) Sulfur) phenyl 1-546 phenyl CH CH CH H H 2,6-dibromodong (2 bis 2-trifluoroethyl thio)phenyl 1-547 2-1 phenyl CH CH CH H H 2,6 -two> stinky -4-(2,2,2- Gas ethyl thio)phenyl 1-548 2-chloro 0 to °-3-yl CH CH CH CH HH 2,6-di > odor-4-(2,2,2-disorganoethyl sulphate) 1-49 4-Nitrophenyl CH CH CH CH HH 2,6-di> Odor-4-(2,2,2-disorder ethylthio)phenyl 1-550 Styyl CH CH CH CH HH 2,6-diox-4-mercapto-unsupplied 1-451 phenyl CH CH CH CH Me ,H 2,6-diox-4-yl-phenyl-1-552 phenyl CH CH CH CH HH 4-Amino-2,6-dichlorophenyl 1-553 phenyl CH CH CB CE HH 4-cyano-1-indolyl-3-(4-trifluorodecylphenyl)-1H- Pyrazol-5-yl 1-554 phenyl CH CH CH CH H 4- 4-decylamino-2,6-dichlorophenyl 1-255 phenyl CH CH CH [CE HH 4-Benzyl hexylamine Base-2,6-dichlorophenyl 90 200836629 Table 1 (29) No excitement number Qi A," 乂,4: Ri q2 1-556 phenyl CH :H( zm ^e: H 2,6 «二漠4methylamine-methylphenylphenyl 1-557 phenyl CH CH< 3H(CH HH K3-chloro-5-trifluoromethylidene-2-yl)pipecyano-1Η-Mimi 》5_基1-558 2-chloroacridine: base CH CHI CHI CH HH 4» cyano-1-methyl sit-5-yl 1-559 fluorophenyl CHi CHi CH丨CH HH cyano cyano-1 -Methyl-ΙΗ-ridge sitting on each base 1-560 CH CH CH CH HH This chaotic-I-second butyl ΊΗ-σ ratio 11 sits ~5-yl 1-561 phenyl CH CH CH CH HH hydroxymethyl each (heptafluoroisopropyl) benzo[ d] inden-2-yl 1-562 phenyl CH CH CH CH HH abundance methyl-6<Φ trifluoromethylphenylpyridin-5-yl 1-536 phenyl CH CH CH Me Me 2, 6·二漠1-564 phenyl CH CH CH Me H 2, 孓 dibromo 嗤 4 )) phenyl 1-565 phenyl CH CH CH CH HH 2,6-dibromo 4<U3-嗟二嗤4»yl)phenyl 1-536 phenyl CH CH CH cri HH heptafluoroisopropyl-2-carbylmethylphenyl 1-567 phenyl CH CH CH CH Me H 'heptafluoroisopropyl 2-Phenyl-p-phenylphenyl 1-568 phenyl CH CH CH CH H 七七气isopropyl-2-methyl hydrazine 醯 氧 氧 各 each 1-methyl phenyl 1-69 phenyl CH CH CH CH Me T: sevoflurane isopropyl-2-trifluoromethanesulfonyloxyl decylphenyl 1-570 phenyl CH CH CH CH :Me H 2-ethyloxy car Ι Ι isopropyl 曱Phenylphenyl 1-571 phenyl CH CH CH CH [HH Benqi isopropyl: hydroxy fluorenyl decyl phenyl 1-572 phenyl CH CH [CH CE [HH hexafluoroisopropyl-2- Methoxymethylmethylmethyl 1-753 phenyl CH CK [CE C E [HH 2-mercaptopurine-based heptafluoroisopropyl>6-trifluorodecylphenyl 1-574 stupyl CH CE [Ct Cl·. E 2-bromochloro-, 5-dichloro · Benz-2-yloxy)phenyl on 575 phenyl CH Cl · ICt Ct ΪΜ (2-bromo·4<3-chloro-5-trifluoromethyl.定-2-_ [Each methylphenyl 91 200836629 Table 1 (30) No. 1-576 Qi Α9! α'2 A,3 A'4 Ri Qi Stupid CH CH CH CH HH 2-Bromo 4-(3 -gas>5-trifluoromethyltonene 2-yloxy>6»methylphenyl 1-577 2-fluorophenyl CH CH CH HH 2- desert 4 <3-chloro-5-trifluoro Methyl-den-2-yloxymethylphenyl 1-577 2,6-«-gas phenyl CH CH CH H H 2 2 lacquer 4 <3-chloro-5-trifluoromethyl 1 1,4-yl Oxygen>6-methylphenyl 1-475 2-chloro-di--3-yl CH CH CH CH HH 2·bromo-t-(3-chloro·5-trifluorodecyl-butenyl-2-yloxycarbonyl) Phenyl 1-580 phenyl CH CH CH CH H H 2-chloro-, 5-dichloro-butoxy-2-yloxy)phenyl 1-581 stupyl CH CH CH CH HH 2-chloro 4{benzobenzene Base>»6 «trifluoromethylthiophenyl 1-582 2-chloro port specific -3--3-phenylphenyl CH CH CH H 2-chloro·4<4·fluorophenyl)>6» Trifluoromethylthiophenyl__一一一1-583. 1-584 Silk CH CH CH CH HH Φ(2,Φbis(trifluoromethyl)phenyl>«2-chlorotrifluoromethyl琉Phenyl-phenyl CH CH CH CH Me H 4-(3,5-bis(trifluoromethylyiH-Ab sitting-1-yl) "2,6"Dibromophenyl 1-85 ___—1 -586 2-Phenylphenyl CH CH CH CH Me H Φ( 3,5-bis(trifluoromethyl)>2,6·dibromophenyl 2-chloro-oryl group CH CH CH OH Me H Φ(3,5-bis(trifluoromethyl-seat- 1-based>2,6·dibromophenyl 1-587 phenyl CH CH CH HH Φ(3,5-bis(trifluoromethyl)<lH-u 嗤-μ 〇 漠 漠 漠 漠1-588 ^——- 1-589 2-fluorophenyl CH CH CH IH H : Φ(3,5-bis(trifluoromethyl)4Η is more than salivary 4-based>2,6«dibromo Base 2-Chloroport ratio σ, 3-based CH CH CH CK IH H : 4 < 3,5-bis(trifluoromethyl)41^ than 嗤4-;^>2,6»dibromophenyl 4»fluorophenyl CH CH :CH CE IH H [4>(3,5-bis(trifluoromethyl>1H-byw) 1-base) 2,6·di^phenyl 92 200836629 Table 1 (31)

Compound No. Qi Α5! a,2 A,3 A'4 Ri r2 q2 1-591 Phenyl CH CH CH丨CH Me H ' K3,5-bis(trifluoromethyl hydrazone &gt; 1H) than hydrazine base &gt; 2 kg of dichlorophenyl 1-592 phenyl CH CH CH H H 4 &lt;3,5-bis(trifluoromethyl)&gt;1Η-♦sitting-1-ylindenyl) -2-&gt;Smelly~6~ Methyl group 1-593 2-fluorophenyl CH CH CH HH Φ(3,5-bis(trifluoromethyl)4H^b嗤4-ylmethyl)-2-bromomethylphenyl 1- 594 2-Chloropurine-3-yl CH CH CH CH HH Φ(3,5-bis(trifluoromethyl)4H-u 嗤4-ylmethyl)-2-&gt;Smelly~6~曱Phenylphenyl 1-95-phenyl CH CH CH CH Me H Φ(3,5-bis(trifluoromethyl-spin-4-ylmethyl)-2-&gt; odor-6-methylphenyl 1-956 benzene CH CH CH CH HH 5-bromo-7«(heptafluoroisopropyl h2,3-di IrlH-indole group 1-597 2-1 phenyl CH CH CH CH HH 5-bromo-7·(seven | L-isopropyl&gt;2,3-dihydro 4H-based 1-598 phenyl CH CH CH CH HH 5-chloro-7-(heptafluoroisopropyl)-2,3-dihydro-1H-imprint 4 ·Base 1-599 2-fluorophenyl CH CH CH CH HH 5-chloro-7·(seven isopropyl)-2,3_diazo-1H-讳*4·yl 1-600 2-benzene Base ca [CH CH CH [Me H 丰 methyl each {2>&gt; trifluoro τΚ trifluoromethyl) ethoxy} Oral ratio -3-; ^ 1-601 phenyl CF CH CH CF T TJ 4-heptafluoroisopropyl-2-methylphenyl 1-602 stupid ca [CH CH ; CH [HH 2,4 Bis(trifluoromethyl)phenyl 1-603 2-fluorophenyl CH CH CH [CK [H Me 4-heptafluoroisopropyl 2-methyl fluorenylphenyl 1-604 phenyl CE [CH CE [CF [H n-Bi 3 2-dibutyl 4·heptazole isopropylphenyl 1-605 phenyl CB [CH CB [Cl· IHH 2-chloro-6·dimethyl thiophenyl) 93 200836629 Table 2(1) Chemical substance number Qi a,2 A,3 A,4] R4] q2 2-1 Phenyl CH CH丨CH CH HH: 2,6·Dibromo-4-(151,2 ,3,3,3-hexafluoropropoxy)phenyl 2-2 2-methylphenyl CH CH CH H HH: 2,6-dibromo-4-(1,1,2,3,3, 3-hexafluoropropoxy)phenyl2-3-3-methylphenyl CH CH CH H HH: 2,6-dibromo-4-(1,1,2,3,3,3-hexafluoropropyl Oxy)) 2-4 4-mercaptophenyl CH CH CH H H: 2,6-dibromo-4-(1,1,2,3,3,3-hexafluoropropoxy)phenyl 2-5 2-ethylphenyl CH CH CH H H 2 2,6-dibromo-4-(1,1,2,3,3,3-hexafluoropropoxy)phenyl 2-6 3-B Phenylphenyl CH CH CH CH HH 2,6-dibromo-4-(l,l,2,3,3,3-hexafluoropropoxy)phenyl 2-7 4-ethyl CH CH CH CH HH 2,6-Dibromo-4-(1,1,2,3,3,3-hexafluoropropoxy)phenyl 2-8 2-fluorophenyl CH CH CH H H 2 ,6-Dibromo-t-(1,1,2,3,3,3-hexafluoropropoxy)phenyl 2-9 3-fluorophenyl CH CH CH CH HH 2,6-dibromo-4-( 1,1,2,3,3,3-hexafluoropropoxy)phenyl 2-10 4-phenylphenyl CH CH CH CH HH 2,6-dibromo ice (1,1,2,3,3 ,3-hexafluoropropoxy)phenyl 2-11 2-chlorophenyl CH CH CH H H 2 2,6-dibromo-4-(1,1,2,3,3,3-hexafluoropropoxy Phenyl 2-12 3-chlorophenyl CH CH CH H H 2,6-dibromo-4-(1,1,2,3,3,3-hexafluoropropoxy)phenyl 2-13 4-Chlorophenyl CH CH CH CH HH 2,6-Dibromodong (1,1,2,3,3,3-hexafluoropropoxy) phenyl 2-14 2-bromophenyl CH CH CH CH HH 2,6-dibromo ice (1,1,2,3,3,3-hexafluoropropoxy)phenyl 2-15 3-&gt; stinyl phenyl CH CH CH CH HH 2,6-two desert -4-(1,1,2,3,3,3-hexapropoxy)phenyl 246 4-bromophenyl CH CH CB CH HH 2,6-dibromo-4-(1,1,2 ,3,3,3-hexafluoropropoxy)phenyl 2-17 2-Ethyl CH CH CH [CH HH 2,6-dibromo;-4-(1,1,2,3,3, 3-hexafluoropropoxy)phenyl 2-18 3-sphere·local CH CH CH [CH HH 2,6-two desert-4-(1 ,1,2,3,3,3-hexapropoxy)phenyl 2-19 4-iodophenyl CH CH CH [CH :HH :2,6-dibromo-4-(1,1,2 ,3,3,3-hexafluoropropoxy)phenyl 2-20 3-cyanophenyl CH CH [CH ;H :2,6-dibromo-4-(1,1,2,3, 3,3-Hexafluoropropoxy)phenyl 94 200836629 Table 2(2) Chemical number Qi A5! A'2 A, Μ Ri r2 —----- q2 2-21 4-cyanophenyl CH CH CH CH HH —--- 2,6·dibromo 4 (1,1?2,353,3-hexafluoropropanol) stupid 2-22 2-nitrophenyl CH CH CH H H 2,6» two Bromine"4&lt;1,1?2,33,3-hexafluoropropoxylate| 2-23 3-石肖基 CH CH CH CH HH 2,6«Dibromo 4{1,1523,33-hexafluoropropyl菩样苍2-24 nitrophenyl CH CH CH CH HH 2,6·—Carriage ^ Magic ^- hexafluoropropanyl base 2-25 2-Aminophenyl CH CH CH CH HH -- ------ 2'6~-Bromo-4-(1,1^233,3-hexafluoropropyl) Qi Weiqi 2-26 2-27 3-Aminophenyl CH CH CH H HH 3, 3,3-hexaoxy) acesulfame phenyl CH CH CH CH HH dibromo-4-(1,152,3,3,3-hexa-propionate, f 2-28 2-trifluoro Nonylphenyl CH CH CH CH HH 2, & Erm-4^142333-hexafluoropropionate as its 2-29 3-trifluoromethylbenzene CH CH CH CH HH Dibromo·4&gt;(1,1,3,3,3-six gas rain g, 苠2-30 4*trifluoromethylphenyl CH CH CH H H 2,6-- 》臭-4-(1,1 ^23,3,3-六翕13⁄4 备1, also basin 2-31 2-Phenylphenyl CH CH CH CH HH 2方&quot;二溪4·(1,ΐ52 , 3,3,3-hexafluoropond from its 2-32 2-decyloxyphenyl CH CH CH CH HH 2,6-dibromo 4-(1,1^2333-hexafluoro and its It is 2-33 3-decyloxyphenyl CH CH CH CH HH 2,6-dibromo 4-(1,1^23,3}hexafluoro and is read by its 2-34-fluorenyloxyphenyl CH CH CH CH HH 2,6-dibromo-4&quot; (1,1 and 3,3,3-hexafluoro and 毚 from its 2-35 2-phenoxyphenyl CH CH CH H H (1,1?2,3,3,3-hexa-propion, its letter 2-36-didecylethyl) phenyl CH CH CH CH HH 256-—/^4-(1,1^333- 7^3⁄4 a 2-37 3 仁曱纽基) phenyl CH CH CH :CH HH 2,6-二漠-4-(1,152,3,3,3-六_ _2-38 4·(二曱细Phenyl CH CH CE [CH HH _ 1 二漠"μ(ΐ,1,3,3,3-:^ turtle and oxy) stupid 2-39 fluorene trifluoromethoxyphenyl lOH CH CH [CE [HH 2,6-二漠-4-(1,1^2333-六氤丙® its ^ laugh its 2-40 2 fluorenylamino) phenyl | ck [CH CF ICE [HH San Mo 95 200836629 Table 2 (3) No. Qi Α?! a, 2 A, 3 A54 Ri r2 q2 241 3·{Ethyl) phenyl CH CH CH CH HH ------ 2,6»dibromo 4-(1,1?2,3,33-hexafluoropropoxy)phenyl 242 abundance (acetamidoamine)phenyl CF CH CH CH HH 243 2-acetoxy CH CH CH CH H H 2,6 «Second Moist (1,1?2,3,3,3-hexafluoropropanol) extract 244 2~(methyl)phenyl CH CH CH CH HH 2, 6»二漠-4{1,1?2,3,3,3-hexafluoropropoxyphene) 245 4&quot;(methoxylatyl)phenyl CH CH CH CH HH bromine winter (10) magic ^ - Hexafluoropropyl fistula 246 23-dimethylphenyl CH CH CH H H 2,6 · Er Mo 3,3,3-hexafluoropropene _ 帑 帑 247 2,Φ dinonylphenyl CH CH CH CH HH 2,6»Dibromo bucket (1,1?2,3,33-hexafluoropropoxy)-butyl 248 2,6&gt;dimethylphenyl CH CH CH H H 2,6»二漠4{1,1?2,3,3,3-hexafluoropropene 芊 sign) 249 2,3-difluorophenyl CH CH CH H H 2,6&gt;二漠4&quot;(1,1 ?2,3,3,3-hexafluoropropene|[Very narrow] 2-50 2, 'difluorophenyl CH CH CH CH HH 2,6 dibromo·Φ (1,1 and 333-hexafluoropropyl Fengji) Sheep base 2-51 2,5-difluorophenyl CH CH CH H H 2,6 »二漠4&lt;1,1?2,3,3,3-hexafluoropropanthine) Ping-Ping 2-52 2 nd difluorophenyl CH CH CH CH HH 2, Fuyi > Smelly Winter (1, 152,3,3,3-hexafluoropropyl-yl) palm 2-53 3,Φ difluorophenyl CH CH CH CH HH 2,6--&gt;Smelly 4-(1,152,3,3, 3-hexafluoropropyl group) stupid tomb 2-54 3&gt; difluorophenyl CH CH CH H H 2 2, dibromo 4 (1,1 and 3,3,3-hexafluoropropanone climbing 荃2- 55 2,3-Dichlorophenyl CH CH CH CH HH 2,6--Moist 4-(1,1523,3,3-hexa-propanyl)-yl 2-56 2,4-dichlorophenyl CH CH CH CH HH 2,6»Dibromo"4&lt;1,1 and 3,3,3-hexafluoropropane climbing) Benzene 2-57 2"Dichlorophenyl CH CH CH CH HH 2,6- —溪4-(1,152,3,3,3-six rat propoxyl ^^2- 2- 2 2, 孓dichlorophenyl CH CH CH :OH HH 2,6*二溪4&lt;1,1 ?2,3,3,3-hexafluoropropene|1 sign) section sign 2-59 3,4«dichlorophenyl CH CH CH LCE [HH hexafluoride two-handed sign) 2-60 Schottky phenyl CH :CH CH [OH [HH --------- 2 Jieyi / stinky car (W again 3,3,3_hexafluoropropoxy)phenyl 96 200836629 Table 4) &lt;匕For the numbering Qi a, 2 A53 A54 Ri r2 Q2 2-61 Schottyl phenyl CH CH CH<CH HH 2,6&gt; Dibromo 4 (1,1?2,3,3,3 -hexafluoropropoxy)phenyl 2-62 2,6·dimethoxyphenyl CH CH CH丨CH HH 2,6«dibromo car (1,1 and 3,3,3-hexafluoropropoxy Phenyl 2-63 3&gt;dimethoxyphenyl CH CH CH H H 2 ,6&gt;dibromo 4-(1,123,33-hexafluoropropoxy)phenyl 2-64 3-methyl 4» Nitrophenyl CH CH CH H H 2 , Fu Er Mo 1 (1,1?2,3,3,3-hexafluoropropoxy)phenyl 2-65 5-Amino-2-phenylphenyl CH CH CH CH HH 2,6·Dibromo 4(1,1^23,33-hexafluoropropoxy)phenyl 2-66 3-fluoro-2-indolylphenyl CH CH CH HH 2,6· Dibromo 1(1,1?2,3,3,3-hexafluoropropanyl-2-phenyl 2-fluoro-5-schhoffylphenyl CH CH CH HH 2,6«dibromo&gt;4{1 ,1?2,3,3,3-hexafluoropropoxy)phenyl 2-68 4-Den-3-Shischyl Phenyl CH CH CH CH HH 2,6-Dibromo 4&lt;1,1?2, 33,3-Hexafluoropropoxy)phenyl 2-69 5-Gas-2-Gentocylphenyl CH CH CH CH HH 2,6«Dibromo 4&lt;1,1;2,3,3,3- Hexafluoropropoxy)phenyl 2-70 2-gas-6-mothyl CH CH CH CH HH 2,6·dibromo 4C1, U3,33-hexafluoropropoxy) phenyl 2-71 2- Fluoro-5-di-1-methylphenyl CH CH CH CH HH 2,6·dibromo 1(1,1?2,3,3,3-hexafluoropropoxy)phenyl 2-72 2-chloro- 4·Shi Xiaoji CH CH CH CH HH 2 kg of dibromo 4&lt;1,1 and 3,33-hexafluoropropoxy)phenyl 2-73 2-chloro·4~disorganophenyl GH CH CH HH 2,6-II Bromohexafluoropropoxy)phenyl 2-74 2-chloro-6·gasphenyl CH CH CH CH HH 2,6·dibromo 4&lt;1,1 and 3,3,3-hexafluoropropoxy) Phenyl 2-75 3, chloro-4-like phenyl CH CH CH [OH HH 2,6&gt; Dibromo bucket (1,1^2333-hexafluoropropoxy)phenyl 2-76 4-chloro-2 -1phenyl CH CH CH CH HH 2,6»二漠冬(1,1?2,3,33-hexafluoropropoxy)phenyl 2-77 4»Chloro-2-stone basementyl CH CH CE [CE IHH 2,6·dibromo 4&lt;1,1?2,353,3-hexafluoropropoxy)phenyl 2-78 3-decyloxycar Shikiylphenyl:CH;CH [CE ICF. IHH 2, 6·Dibromo- winter (1,1?2,3,3,3-hexafluoropropoxyl)phenyl 2-79 2-methoxy 4 «renylbenzene, CH [CE [a ICF IHH 2, 6»二漠4(1,12333-hexafluoropropoxy)phenyl 2-80 2,3,4«trifluorophenyl CE [CH [a Id IHH 2,6·dibromo 4&lt;1, U3, 3,3-hexafluoropropoxy)phenyl 97 200836629 Table 2 (5)

No. Qi A?! a'2 AA, Ri r2 Qi 2-81 2,4,6&gt; Trimethylphenyl CH CH CH(CH HH 2,6·Dibromo-冬(1,U3,3,3-Six Fluoropropoxy)phenyl 2-82 2,3,6·trifluorophenyl CH CH CH丨CH HH 2,6·dibromo l (l,l and 3,3,3-hexafluoropropoxy) Phenyl 2-83 2,4,5-trimethoxyphenyl CH CH CH H H 2,6&gt;Two preparation vehicles (1,192,3,3,3-hexafluoropropoxy)phenyl 2-84 3,4,5-trimethoxyphenyl CH CH CH H H 2 2,6·二漠冬(1,1,3,3,3-hexafluoropropoxy)phenyl 2-85 2,3,4 ,5,6«pentafluorophenyl CH CH CH CH HH 2,6·dibromo 1 (1,1 and 3,3,3-hexafluoropropoxy)phenyl 2-86 2-biphenyl CH CH CH CH HH 2,6-dibromo bucket (1,1?2,3,3,3-hexafluoropropoxy)phenyl 2-87 3-biphenyl CH CH CH CH HH 2,6~2^ Stinky 4{1,1?2,3,3,3-hexafluoropropoxy)phenyl 2-88 1-Cai CH CH CH CH HH 2,6·dibromo l (l, U3, 33-six Fluoropropoxy)phenyl 2-89 2-naphthyl CH CH CH CH HH 2,6»dibromo 4&lt;1,1; 2,3,3,3-hexafluoropropoxy)phenyl 2-90 11 to 0-but-2-yl CH CH CH CH HH 2,6·二漠4^1,1 and 333-hexafluoropropoxy)phenyl 2-91 ^ 比口定-3-;^ CH CH CH CH HH 2,6-dibromo 4&lt;1 1 again 3,3,3-hexafluoropropoxy)phenyl 2-92 *Dedyl CH CH CH CH HH 2,6·dibromo 4»(1,U3,33-hexafluoropropoxy)benzene 2-93 2-methyl nfcb2 determinate-5-yl CH CH CH CH HH 2, Fu Er Mo 4 &lt;1,152,3,3,3-hexafluoropropoxyphene 2-94 3-methyl Oral ratio of 2-yl CH CH CH OH HH 2 dibromo-methanol (1,1 2,3,3,3-hexafluoropropoxy)phenyl 2-95 2· defeated -3-yl CH CH CH CH HH 2 knows dibromo^K1, U3,3,3-hexafluoropropoxy)phenyl 2-96 2-gas. Ding-3-yl CH CH Oi CE HH 2,6&gt; Er Modong (1,1;2,3,3,3-hexafluoropropoxy)phenyl 2-97 2-chloro port ratio *4 ·Base CH CH CH CK HH 2,6&gt;Dibromo 1 (1,1 and 3,33-hexafluoropropyl)phenyl 2-98 2-port ratio -6-based CH CH CH :CE IHH 2 ,6&gt;Dibromoindole (1,1,3,3,3-hexafluoropropoxy)phenyl 2-99 2, chlorophenanthylamine-5-yl CH CH :CH a IHH 2,6·2 Indifference to pheno%-hexafluoropropoxy)phenyl 2400 5-yi/Butyl-2-yl OH CH [OH a IHH 2 知二漠 hexafluoropropoxy)phenyl 98 200836629 Table 2 (6) Do not number Qi Α9! α'2 A'3 A,4: Ri r2 q2 2-101 4~ Dimethylmethyl 0 to 0 -3--3-CH CH CH CH HH: 2, Fu Er Mo 4&lt;1, 1 and 3,3,3-hexafluoropropoxy)phenyl 2-102 ratio °-2-^^ CH CH CH CH H Π: 2,6·二漠#1,12333-hexafluoropropoxy Phenyl 2403 2-phenoxy ° ratio.定-3_基CH CH CH CH HH: 2, Fulbazo 1 (1,1?2,3,3,3-hexafluoropropoxy)phenyl 2-104 2-mercaptosulfate ratio -3-yl CH CH CH CH HH 2, Fu Er Modou ^^力乂 hexafluoropropoxybenzene phenyl 2-105 2,6·dimethyl emulsion base ratio -3-yl CH CH CH CH HH 2,6 «二漠4&lt;1,1 and 3,3,3-hexafluoropropoxy)phenyl 2406 2,3-dichlorocadine-5-yl CH CH CH CH HH 2,6-di ilHKU Further 3,3,3-hexafluoropropoxy)phenyl 2407 2,5-dichloroindol-3-yl CH CH CH CH HH 2,6·2 desert 4 (1,1 and 333-hexafluoropropyl Oxy)phenyl 2-108 2,6-dichloroport ratio. Ding-3-yl CH CH CH CH HH 2,6·di/odor '4-{1,1?2,3,3,3-hexafluoropropoxy)phenyl 2-109 3,5-dichloro *定冬基 CH CH CH CH HH 2,6~二漠4&lt;1,192,3,3,3-hexafluoropropoxy)phenyl 2-110 Qiu Yukou Ding-N-Oxygen 4 b~2 -Base CH CH CH CH HH 2,6-二^臭·车(1,1,3,3,3-hexafluoropropoxy)phenyl 2411 N-methyl^pyro-*~2-based&gt; CH CH CH CH HH 2 Zhi Er Mo 4&lt;1:,1?2,3,3,3-hexafluoropropoxy)phenyl 2-112-portage- -2-yl CH CH CH CH HH 2,6· Dibromo, hexafluoropropoxybenzene phenyl 2-113 2H than hept-5-yl CH CH CH CH H 2 2,6 · dibromo car hexafluoropropoxy) phenyl 2414 4 * trifluoromethyl Kefuding-5-yl CH ce CH CH HH 2, Fu Er Mo 4{1,192,3,3,3-hexafluoropropoxy)phenyl 2-115 σ Fukou Nan-2-yl CH CH iCH CH HH 2,6»二漠4(1,U3,33-hexafluoropropoxy)phenyl 2-116 benzo-3-yl CH CH [|CH CH HH 2, bis 2 bromo 4 (1/ 1233,3-hexafluoropropoxyl D-phenyl 2-117 2-tetrahydrofurfuryl CH CH [CH CH :HH 2,6&gt;dibromo 3-hexafluoropropoxyphenyl 2418 3-tetrahydrofuranyl CH CK [CH CH :HH 2,6»II hexafluoropropoxy)phenyl 2-119 benzopyran-2-yl CH Or DCH :CH [HH 2, 孓二漠1(1,12333-hexafluoropropoxy)phenyl 2420 tetrahydrofuran-2-yl CH Ct ICH :CH [HH 2 kg 2 ^々^", ,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, 4H - Oral-3-yl CH CH CH CH HH : Yu Erqian 3-hexafluoropropoxy)phenyl 2-122 2- 2- 2-yl CH CH CH CH HH : 2,6_二漠斗( 1,1,3,3,3-hexafluoropropoxy)phenyl 2-123 σ-port +3-based CH CH CH CH HH : 2,6· 二漠 3,3-hexafluoropropoxy) Phenyl 2424 3-methyl phenanthrene-2-yl CH CH CH CH HH : jin 2 odor ^^ with illusion: ^-hexafluoropropoxyl phenyl 2-225 2-shi Xiaojikou phenanthene 4~ CH CH CH CH HH : 2,6 «二漠~4&lt;1,U33,3-hexafluoropropoxy)phenyl 2-126 2-methyl fluorene-based CH CH CH CH HH : 2,6 «二漠4-(1,1^233,3-hexafluoropropoxy)phenyl 2-127 3 marriage 2-based CH CH CH CH HH 2 winter dibromo winter (1,1 and 3,3, 3-hexafluoropropoxy)phenyl 2-128 2-Chloro-port 7-based CH CH CH CH HH 2,6»Dibromo 4»(1,1 2,3,3,3-hexafluoropropane Oxy)phenyl 2-129 3-bromophene·2- CH CH CH CH H H 2,6 · Winter dibromo (1,1 and 3,3,3-hexafluoro-propoxy) phenyl 2430 2- &gt; smell. Plug mouth ^-5-based CH CH CH CH HH 2,6&gt; Er Modong (1,1 and 3,33-hexafluoropropoxy)phenyl 2-131 CH CH CH CH HH 2,6-two&gt ; stinky ice (1,152,3,3,3-hexa-propyl propyl) phenyl 2432 3-phenyl-in 2-based CH CH CH CH HH 2,6·two hexafluoropropyl phenyl) phenyl 2433 2,4»dimethyl 1 parameter *5-based CH CH CH CH HH 2 kg 2 odor 4 &lt; 1,1 and 3,3,3-hexafluoropropoxy)phenyl 2434 benzoquinone port ^&quot;2_基CH CH CH CH HH 2,6·Dibromo bucket (1,1?2,3,3,3-hexafluoropropoxy)phenyl 2-135 CH CH CH CH HH 2, dibromobutan (1/1?2,3,3,3-hexafluoropropoxy) phenyl 2-136 3-ethyl-3H* sitting 4 based CH CH CH CH HH 2,6·dibromo- winter (Imaginary)-hexafluoropropoxyphene 2-137 1-methyl-3-nitro 4H-吼口坐冬基 CH CH CH CH HH 2,6-二&gt Odor 4-(1,152,3,3,3-hexafluoropropoxy)phenyl 2-138 3-chloro-4-methyl-IHwb sitting on 4 base CH CH CH :CH L Π H 2,6 · bis 3-hexafluoropropoxy)phenyl 2-139 3-wet 4-methyl-1H-indole CH CH : OH [CE [HH 2,6* dibromo 4 &lt; 1, U3, 33- Hexafluoropropoxy)phenyl 2-140 1-methyl-3-trifluorodecyl CE :CH :CE [CE [HH 2,6»3 stinky Winter (以^^-hexafluoropropene^^phenyl 100 200836629 Table 2 (8) Framing number Qi A a'2 A93 A,4 Ri r2 Q2 2441 1-methyl&gt;5-trifluoromethyl-1H - mouth mouth is sitting on the winter base CH CH CH CH HH: 2 knows dibromo- 4&lt;1,192,3,3,3-hexafluoropropoxyphenophenyl 2-142 isoindole-5-yl' CH CH CH CH HH : 2, 孓二漠斗^:^^土 hexafluoropropoxyl phenyl 2-143 4&gt; trifluoromethyl fluoren-5-yl CH CH CH CH HH : 2, & (1,1?2,33,3-hexafluoropropoxy)phenyl 2-144 2,Φ diindolyl-5-yl CH CH CH CH HH : 2,6&gt;Two desert vehicles (1, 1? 2,33,3-hexafluoropropoxy)phenyl 2-145 2-ethyl-p-methyl. Plug. -5-based CH CH CH CH HH 2,6·dibromo 4(1,U333-hexafluoropropoxy)phenyl 2-146 2-chloro-4-methylguanidin-5-yl CH CH CH CH HH 2,6·dibromo 1(1,192,33,3-hexafluoropropoxy)phenyl 2-147 3-methyl-isoindole-5-yl CH CH CH CH HH 2,6·2 Bromine (1,1,3,3,3·hexafluoropropoxy 1)benzene* 2-148 3,Φ dichloro-isoindole-5-yl CH CH CH CH HH 2, Fu Er Mo 4 (1 ,1 meaning 3,3&gt;hexafluoropropoxy)phenyl 2-149 3-chlorobenzo--2-yl CH CH CH CH HH 2,6«dibromo 4 (1,1^23,33-six Fluoropropoxy)phenyl 2-150 difluoro-benzo[1.3]]fazole-5-yl CH CH CH CH HH 2,6·dibromo 4 (1,1 2 3β,3-hexafluoropropene Phenyl 2451 difluoro-benzo[13]dienyl CH CH CH CH HH 2,6·dibromo 4 (1,1 and 3?3,3-hexafluoropropoxy)phenyl 2-152 benzene CH CH CH CH H H 2,6·Second (1,1 2,3,3,3-hexafluoropropoxy)phenyl 2-153 m phenyl CH CH CH H H 2,6&gt; (1,123,3,3-hexafluoropropoxy)phenyl 2-154 4·fluorophenyl CH CH CH CH HH 2,6·二漠冬(1,1;2,353,3-hexafluoropropoxy) Phenyl 2455 4 · 鼠基基CE CH CH CH HH 2,6·dibromo 4^12333-hexafluoropropoxy)benzene S 2-156 2-Chloro-port 唆-3-yl OH CH CH CH HH 2,6·Dibromo- winter phantom hexafluoropropoxy group 2-157 β-Schiffkiphenyl CK CH CH CH HH 2, bismuth dibromide 4(U; 2353,3-hexafluoropropoxy)phenyl 2-158 4»cyanophenyl OE CH :ce CH HH 2,6»二^臭4(1,U33,3-hexafluoropropoxylate Phenyl 2- phenyl phenyl CE CH : CH : CH : M ( ^ H 2, 6 > dibromo (1,1?2,3,33-hexafluoropropoxy)phenyl 2460 2-fluoro Phenyl CF CH ; CH : CH : M ( 2,6 « 二漠 4(1,1?2,3,3,3-hexafluoropropoxy)phenyl 101 200836629 Table 2 (9) Qi A5! a'2 A'3 A'4 Ri r2 Q2 2461 4·fluorophenyl CH CH CH CH Me H 2,6&gt; Er Mo 4&lt;1,1 and 3,3,3-hexafluoropropene-benzene 2-162 chlorophenyl CH CH CH CH Me H 2,6·dibromo 4 (1,1?2,3,3,3-hexafluoropropoxy)phenyl 2-163 2-chloro port ratio Ordin-3-yl CH CH CH CH Me H 2 Dibromo-KU 2,3,3-hexafluoropropoxy)phenyl 2-164 nitrophenyl CH CH CH CH H 2,6 «Dibromo 4&lt;1,1 and 3,3,3-hexafluoropropoxy)phenyl 2-165 cyanophenyl CH CH CH CH H H,6&gt;dibromohexafluoropropoxy)benzene Base 2466 phenyl CH CH CH CH H Me 2,6&gt; Er Mo 4«(1,1 Further 3,3,3-hexafluoropropoxy)phenyl 2467 2-fluorophenyl CH CH CH H Me 2,6~2^Winter hexafluoropropoxy)phenyl 2-168 4-phenyl CH CH CH CH H Me 2,6 «dibromohexafluoropropoxy)phenyl 2469 4-chlorophenyl CH CH CH CH H Me 2,6·dibromo-tung Base 2470 2-gas-n-but-3-yl CH CH CH CH H Me 2,6&gt;dibromo 4&lt;1,1?2,3,3,3-hexafluoropropoxy)phenyl 2-171 Nitrophenyl CH CH CH CH H 2 2,6·dibromo 4&lt;1,1?2,3,33-hexafluoropropoxy)phenyl 2-172 phenyl CH CH CH H Me 2,6 ·Dibromo 4(1,1,3,3,3·hexafluoropropoxy)phenyl 2-173 2-chloro-3-stone schylyl CH CH CH CH H Me 2,6·dibromo·Φ{ 1,1,2,33,3-hexafluoropropoxyphenephenyl 2-174 phenyl CH CH CH Me Me 2,6·二漠4(1,U3,33-hexafluoropropoxy)phenyl 2475 2 -fluorophenyl CH CH CH Me Me 2 knows 2^1&lt;1,1?2,33,3-hexafluoropropoxy)phenyl 2-176 4-phenylphenyl oxime CH CH CH Me Me 2, 6·二漠4(1,;1?2,3,3,3-hexafluoropropoxy)phenyl 2-177 4·gas phenyl CH CH CH CH Me Me 2,6&gt; ,1,3,3,3-hexafluoropropoxy)phenyl 2-178 2-purine oxime-3-yl CH CH CH CH Me Me 〉2,6-di; odorous hexafluoropropoxy)phenyl 2-179 nitrophenyl CH CH CH Me Me 〉2, Fu Erqian-4&lt;1,1;2, 3,33-hexafluoropropoxy)phenyl 2-180 4»cyanophenyl CH CH CH Me Me : 2,6·dibromo and 3,3,3-hexafluoropropylphenyl 200836629 (10) No. Qi a'2 a'3 A Ri r2 q2 2-181 2-gas well -3-based CH CH CH CH Me Me 2,6·dibromo 4&lt;1,192,3,33- Hexafluoropropoxy succinyl) phenyl 2-182 cryptophene-5-yl CH CH CH CH Me Me 2,6-two deserts (1,1^2333-hexafluoropropoxy)phenyl 2-183 Phenyl CH CH CH CH HH 2-bromo 4&lt;1,1?2,3,3,3-hexafluoropropoxy)^methylphenyl 2484 Phenyl CH CH CH CH Me H 2-Bromodong (U ^W-hexafluoropropoxy group> each trifluoromethyl group 2-185 phenyl CH CH CH HH 2-bromo bucket (1,1 and 3,3,3-hexafluoropropoxyspirate&gt;^3 Fluorodecylphenyl 2-186 2-gas-3-port ratio ^^^ CH CH CH CH HH 2-bromo 4&lt;1,1;2,3,3,3-hexafluoropropoxy&gt;6 »Trifluoromethylphenyl 2487 phenyl CH CH CH CH Me H 2-bromo 々^". . . -hexafluoropropoxy group: ridge nitrophenyl 2-188 2-gas·3-σ ratio CH CH CH CH Me H 2-bromo 4&lt;1,192,3,3,3-hexafluoropropoxy^ Retyl phenyl 2-189 phenyl CH CH CH CH HH 2,6·dimethyl"K1,U3,3,3-hexafluoropropoxy)phenyl 2490 2-gas CH CH CH CH Me H 2, 6·Dimethyl 4&lt;1,U3,3,3-hexafluoropropoxy)phenyl 2-191 2-gas 11 specific, 3 based CH CH CH CH Me H 2,6»dimercapto 4&lt ; 1, U33,3-hexafluoropropoxy)phenyl 2492 Phenyl CF CH CH CH HH 2,6·Dimethyl 4&lt;1,152,3,3,3-hexafluoropropoxy)phenyl 2-193 2-fluorogreen CF CH CH CB :HH 2 Dimethyl 1 (1,1 2,3,3-hexafluoropropoxy)phenyl 2494 2-chloro CF CH CH CH [HH 2, 6· dimethyl car (1,1 and 3,3,3-hexafluoropropoxy)phenyl 2495 phenyl CH CF OH [CH [HH 2,6» dimethyl car (1,1 and 3, 3,3-Hexafluoropropoxy)phenyl 103 200836629 Table 2(11) No. Qi A?! a,2 A,3 A,4 Ri r2 q2 2-196 2-Mouse-3-α Than CH CF CH CH HH 2 kg dimethyl car (1,192,3,3,3-hexafluoropropyl) phenyl 2-197 phenyl CH CH CH H H 6 · bromohexafluoropropoxy fluorene) 2- 198 2-Phenylphenyl CH CH CH CH HH 6·Bromo-8&lt;1 1?2,3,3,3-hexafluoropropoxyl lysyl-5-yl) 2-199 2-Chloro-3 look at CH CH CH CH HH 6 · 漠 仏 ^ ^ ^ ^ hexafluoropropyl嗟 嗟 ^ - 2- 2- 2- 2- 2- 2- 2- 2- 2- 2- 2- 2- 2- 2- 2- 2- 2- 2- 2- 2- 2- 2- 2- 2- 2- 2- 2- 2- 2- 2- 2- 2- 2- 2- 2- 2- 2- 2- 2- 2- 2- 2- 2- 2- 2- 2- 2- 2- 2- 2- 2- 2- 2- 2- 2- 2- 2- 2- 2- 2- 2- 2- 2- 2- 2- 2- 2- 2- 2- 2- 2- 2- 2- 2- 2- 2- 2- 2- 2- 2- 2- 2- 2- CH HH 2,6&gt;dibromotetrafluoroethoxy)phenyl 2-202 2-fluorophenyl CH CH CH HH 2,6-di-difluoroethoxy)phenyl 2-203 2-chloro each Mouth ratio ^^ CH CH CH CH HH 2,6~2&gt;Smelly-4-(1,1?292-tetrakis-1ethoxy)phenyl 2-204 Phenyl CH CH CH H H 2 2 Bromine Bis(1,12333-hexafluoropropoxy)phenyl 2-205 2·fluorophenyl CH CH CH CH HH 2- desert 46·double (^^. , hexafluoropropoxy phenyl 2-206 2 · gas -3- mouth ratio CH CH CH CH HH 2- bromo 4,6 · bis (1,152,3,3,3-hexafluoropropoxy Phenyl 2-207 Phenyl CH CH CH CH HH 2,4,6«Tris(1,1 and 3,33·hexafluoropropoxy)phenyl 2-208 2·襄phenyl CH CH CH CH HH 2,4,6&gt;Tris(1,1?2,3,3,3-hexafluoropropoxy)phenyl 2-209 2-chloro-3, mouth ratio. CH CH CH CH HH 2,4, 6-Tris(1,1 and 3,3,3-hexafluoropropoxy)phenyl 2-210 phenyl CH CH CH H H 2 2,6 «dibromo^. ^,"-Hexafluoropropylthiophenyl 104 200836629 Table 2 (12) Hua Zhu Do not number Qi A?! a'2 A'3 A,4 Ri r2 Q2 2-211 Phenyl CH CH CH CH HH 2, 6·二漠4{1,1 and 3,3,3-hexafluoropropylthio)phenyl 2-212 2-chloro each than thiol CH CH CH CH HH 2,6·2^ odor 4{1 ,1?2,3,3,3-hexafluoropropylthio)phenyl 2-213 phenyl CH CH CH HH 2-bromochloro 4^1,1^2,3,3,3-hexafluoro Propylthio)phenyl 2-214 2-fluorophenyl CH CH CH CH HH 2-bromo-chloro 4^123,33-hexafluoropropanyl)phenyl 2-215 2-gas-3-port ratio CH CH CH CH HH 2-bromo-chloro 4&lt;1,1?23,3,3-hexafluoropropylthio)phenyl 2-216 phenyl CH CH CH CH Me H 2-bromo-6&gt;Chlorine 4&lt;1 ,1,3,3,3-hexafluoropropylthio)phenyl 2-217 2-Phenyl CH CH CH CH Me H 2-bromo-chloro 4 (1,U3,3,3-hexafluoropropane sulphur Phenyl 2-218 2-rat CH CH CH CH Me H 2-bromo-chlorobutyric (1,1,3,3,3-hexafluoropropylthio)phenyl 2-219 2-rat-3- Mouth ratio ^^· CH CH CH CH Me H 2,6·dimethyl 1,1&gt;trifluoro-r2-trifluoromethoxy-phenyl- 2-phenyl 2-gas-3·° ratio CH CH CH CH HH 2,6-dimercapto 4-( 1,152,3,33-hexapropoxy)phenyl

105 200836629

Table 2 (13) Correction No. Qi A9! a'2 a, 3 A, Ri Ri Q2 6-1 Phenyl CH CH CH CH HH 2,6-Dimethyl Basic (2_Bromofluoroethyl)phenyl 6-2 2-Chloro*3 -yl CH CH CH CH HH 2,6-Dimethylbromotetrafluoroethyl)phenyl 6-3 Phenyl CH CH CH CH H H 2,6»dimethyl Car (2-bromo-1,1 and 2,fluoroethyl)phenyl 64 2-chloro-port -3-yl CH CH CH CH Me H 2,6-dimethyl·4&lt;2-bromo 4 ,1,2-tetrafluoroethendylphenyl &5 phenyl CH CH CH CH Me H 2-moistry*4&lt;2-bromo-1,0tetrafluoroethylmethylphenyl & 6 2-gas The ratio of CH CH CH CH Me H 2-bromodong (2-bromo-U di-tetrafluoroethyl) 6 «methylphenyl 6-7 phenyl CH CH CH H H 2-bromo (2-Bromo-4,1-2-tetrafluoroethyl-w-methylphenyl 6-8 2-Chloroyl group, CH CH CH CH HH 2-bromo bromide-oxime, ΙΘ-tetrafluoroethyl A Phenyl 6-9 phenyl CH CH CH CH HH 2-bromo-4&lt;2-bromo-1,1 2-tetrafluoroethyl&gt; Trifluoromethylsulfinyl stupid base 6-10 2 Lu Specific conditions CH CH CH CH HH 2-bromo each (2-bromine &quot; UM-tetrafluoroethyl external trifluoromethyl sulfinyl aryl stylyl H1 phenyl CH CH CH CH H H bromo bromide 4, 〇tetrafluoroethyl $ three Methyl hydrazine 笨 笨 642 642 2-Chloro port specific mouth -3, based CH in CH CH : Me : H 2- bromine bucket (2-bromo 4,1 2-fluoroethyl ethyl trifluoromethyl Kea sulfonyl stupid j-------- general formula (B)

(B) N 106 200836629 Table 3 (1) Correction number Qi a, 2 a, 3 A, 4 Ri r2 q2 4-1 Phenyl CH CH CH CH HH 2,6-Dimethyl-4-heptafluoroisopropyl Phenyl 4-2 2-mercaptophenyl CH CH CH HH 2,6-dimethyl-4-heptafluoroisopropylphenyl 4-3 2-1 phenyl CH CH CH HH 2,6· Dimethyl-4-heptafluoroisopropylphenyl 4-4 3-fluorophenyl CH CH CH HH 2,6-dimethyl-4-heptafluoroisopropylphenyl 4-5 4-fluorobenzene CH CH CH CH HH 2,6-Dimethyl-4-heptafluorophenyl 4-6 4-chlorophenyl CH CH CH H H 2 2,6-dimethyl-4-heptafluoroisopropyl Phenyl 4-7 2-bromophenyl CH CH CH H H 2,6-dimethylidene heptafluoroisopropylphenyl 4-8 2_carbophenyl CH CH CH CH HH 2,6·dimethyl Base-4·seven-p-isopropylphenyl 4-9 4-cyanophenyl CH CH CH HH 2,6-dimethyl-4-heptafluoroisopropylphenyl 4-10 2-nitrobenzene CH CH CH CH HH 2,6-Dimethyl-4-heptylisopropylphenyl 4-11 4-nitrophenyl CH CH CH HH 2,6·Dimethylidene heptafluoroisopropyl Phenyl 4-12 2-trifluoromethylphenyl CH CH CH H H 2,6-dimethyl-4-heptafluoroisopropylphenyl 4-13 4-decyloxyphenyl CH CH CH CH HH 2,6-dimethyl -4-heptafluoroi-isopropylphenyl 4-14 2-(ethenylamino)phenyl CH CH CH HH 2,6-dimethyl-4-heptafluoroisopropylphenyl 4-15 2,4-Difluorophenyl CH CH CH CH HH 2,6-Dimethyl-4-heptafluorophenyl 4-16 2,3,4,5,6-pentafluorophenyl CH CH CH CH HH 2,6-dimethyl-4-heptafluoropropylphenyl 4-17 ° ratio. -2--2-yl CH CH CH CH HH 2,6-dimethyl-4-seven isopropylphenyl 4-18 σ 定 -3 -yl CH CH CH CH HH 2,6-dimethyl- 4-heptafluoroisopropylphenyl 4-19 ton -4-yl CH CH CH CH HH 2,6-dimethyl-4-heptafluoropropanyl phenyl 4-20 2- disorder -3-based CH CH CH CH [HH 2,6-dimethyl-4-seven isopropylphenyl 107 200836629 Table 3 (2) Chemicals Do not number Qi A9! a, 2 A, 3 A'4 Ri r2 〇2 4-21 2-gas ϋ 口 -3- -3- CH CH CH CH HH 2, dimethyl benzene hexafluoroisopropyl phenyl 4-22 Ν, oxygen 4 hr0tb mouth -2- CH CH CH CH HH -2,6-dimethyl basic heptafluoroi-isopropylphenyl 4-23 methyl CH CH CH CH H 2 2,6·didecyl 4»heptafluoroisopropylphenyl 4- 24 Methyl CH CH CH CH H 2,6-Dimethyl·4»heptafluoroisopropylphenyl 4-25 Ethyl CH CH CH H H 2,6·Dimethyl carheptafluoroisopropylbenzene Base 4-26 Ethyl CH CH CH CH H H 2,6·Dimethyl ice heptafluoroisopropylphenyl 4-27 2 2-trifluoroethyl CH CH CH CH HH 2,6&gt;Dimethyl Winter sylvestre isopropylphenyl 4-28 2^-trifluoroethyl CH CH CH CH H 2,6&gt; dimethyl car heptafluoroisopropylphenyl 4-29 vinyl CH CH CH CH HH 2 Know Dimethyl Ice Heptafluoroisopropylphenyl 4-30 Vinyl CH CH CH CH Me H 2,6~Dimethyl 1heptafluoroisopropylphenyl 4-31 propyl CH CH CH CH HH 2,6·Dimethyl 4»heptafluoroisopropylphenyl 4-32 propyl CH CH CH CH H 2,6·dimethylso-heptafluoroisopropylphenyl 4-33 Propyl CH CH CH CH HH 2,6~Dimethyl 4»seven isopropylphenyl 4-34 benzyl CH CH CH CH HH 2,6· dimethyl winter seven isopropyl phenyl 4- 37 phenyl CH CH CH H H 2 2 bromofluorene 6·bis(trifluoromethyl)phenyl 4-38 phenyl CH CH CH H H 2,4·bis(trifluoromethyl)phenyl 4-39 phenyl CH CH CH CH HH 2-bromo(heptafluoroisopropyl)&gt;6«(mercaptosulfonyl-phenyl 440 phenyl CH CH CH HH 2,6-dibromo-p-n-n-propylthio)phenyl 441 benzene CH CH CH CH HH 2, Fu 2^4«(heptafluoro-n-propyl sulphate _phenyl 442 phenyl CH CH CH HH 2,6· dimethyl car (nonafluoro τ2-butyl) phenyl 108 200836629 Table 3 (3) Correction No. Qi A5! a, 2 A, A54 Ri Ri Qi 443 Phenyl CH CH CH CH HH 2,6&gt;Dibromo^ (Imaginary)-Hexafluoropropoxy Group 444 Phenyl CH CH CH CH HH 2-bromo winter (1,1 and 3,3,3-six Fluoropropoxy&gt;·6·nonylphenyl 445 phenyl CH CH CH HH 6-&gt;Smelly-8-seven isopropyl hydrazine 1 lea-5-yl 446 phenyl CH CH CH CH HH 2 , ketone dimethyl 4 &lt; 2 · bromotrifluoro-1-trifluoromethyl ethyl) phenyl 447 phenyl CH CH CH H H 2,6 · dichlorotrifluorotrifluoromethyl phenyl phenyl 448 Phenyl CH CH CE CH HH 2,6·dichlorotetrafluoromethylphenyl 449 phenyl CH CH CH HH 2, Φ dibromotrifluoromethylphenyl abundance 50 phenyl CH CH CH CH HH 2 _Bromo 4,6&gt;bis(trifluoromethyl)phenyl abundance 51 phenyl CH CH CH H H 2 2, Φ bis(trifluoromethyl)phenyl 4-52 phenyl CH CH CH HH 2-&gt; Stinky ~6-(2,2-di-gas-1-difluoro-methyl ethoxy group 唆 唆 each base formula (C)

R1 ^ /Qi N

109 200836629 Table 4(1) Compound No. Qi A, a, 2. A, 3- A, 4: Ri r2 Q2 5-1 Phenyl CH CH丨CHi CH HH : 2,6-Dimethyl-4-7 Fluoroisopropylphenyl 5-2 2-methylphenyl CH CH丨CH丨CH HH : 2,6-dimethyl 4-heptafluoroisopropylphenyl 5-3 2-fluorophenyl CH CH丨CH丨CH HH : 2,6-dimethyl-4-seven isopropylphenyl 5-4 3-phenylphenyl CH CH CH H H : 2,6-dimethyl-4-septafluoro Propylphenyl 5-5 4-bromophenyl CH CH CH HH 2,6-diamidino-4-heptafluorophenyl 5-6 2-iodophenyl CH CH CH H H 2,6 - dimethyl-4-seven isopropylphenyl 5-7 4-cyanophenyl CH CH CH HH 2,6-dimethyl-4-seven isopropylphenyl 5-8 2- Nitrophenyl CH CH CH CH HH 2,6-Dimethyl-4-seven isopropylphenyl 5-9 4-nitrophenyl CH CH CH CH HH 2,6-dimercapto-4- Hexaqi isopropylphenyl 5-10 2-aminophenyl CH CH CH CH Π H 2,6-dimercapto_4-heptafluoroisopropylphenyl 5-11 4-aminophenyl CH CH CH CH HH 2,6-dimercapto-4-heptafluoroisopropylphenyl 5-12 3-trifluoromethylphenyl CH CH CH HH 2,6-dimethyl-4-seven isopropyl Phenylphenyl 5-13 2-(ethyl hydrazine Amino)phenyl CH CH CH H H 2,6-dimethyl-4-heptafluoroisopropylphenyl 5-14 4-(ethenylamino)phenyl CH CH CH H H 2,6- Dimethyl-4-seven isopropylphenyl 5-15 2,4-diphenylphenyl CH CH CH :HH 2,6-dimethyl-4-seven isopropylphenyl 5-16 ° ratio. Ding-2-yl CH CH CH CB : H H 2,6-dimethyl-4-seven isopropylphenyl 5-17 0 ratio. Ding-3-yl CH CH CH CH [HH 2,6-dimercapto-4-seven isopropylphenyl 5-18 ° ratio 0 -4--4-CH CH CH CH [HH 2,6-II Methyl-4·heptafluoro-isopropylphenyl 5-19 2-fluoroacridin-3-yl CH CH CH CH [HH 2,6-dimethyl-4-heptafluoroisopropylphenyl 5- 20 2-Chloro 0 ratio °-3-yl CH CH CH CB [HH 2,6-dimethyl-4-seven isopropylphenyl 110 200836629 Table 4 (2) Deuteration not numbered Qi A9! a '2 A,3 A,4 Ri r2丨Q2 5-21 6~&gt;Smelly 0 is more than -2_ base ^ CH CH CH CH HH : 2,6-dimercapto winter sevoflurane 5-22 N-张tr吻定-2-基CH CH CH CH HH 2,6»Dimethyl carheptafluoroisopropylphenyl 5-23 5-amino group 4]噚2, -3-yl CH CH CH CH HH 2,6-Dimethyl-4·heptafluorophenyl 5-24 3-Amino-like 4]噚2, • 5-based CH CH CH CH Π H 2,6~2 Methyl-4-heptafluorophenyl 5-25 5-amino-2H-like 4]tri-n-yl-3-CH CH CH CH HH 2,6-dimercapto-4-heptafluoroisopropyl Phenyl 5-33 1-phenylethyl CH CH CH CH H H, oxadicarbyl 7-isopropylphenyl 5-34 phenyl CH CH CH CH H Me bromo 4,6 «double ( Trifluoromethyl)phenyl 5-35 phenyl CH CH CH CH HH 2, Φ bis(trifluoromethyl)phenyl 5-36 phenyl CH CH CH HH 2-bromo cartas(heptafluoroisopropyl fluorenyl phenyl) 5-phenyl phenyl CH CH CH H H 2 6-Dibromo-4»(heptafluoroJL propyl thio)phenyl 5-38 phenyl CH CH CH HH 2,6&gt; Erqin-4-(seven liL propyl sulphate) phenyl 5-39 Phenyl CH CH CH CH ;HH 2,6-dimethyl-4«(nine gas-2-butyl)phenyl 5-40 phenyl CH CH CH TT 'XI H 2,6«dibromo 4~ (1,152,3,33-hexafluoropropyloxy)phenyl 111 200836629 Table 4 (3) No number (3⁄4 A'i A'2 A'3 A's R2 Q2 541 m CH CH CH CH Η H 2-Bromopropyloxymethylphenyl 542 Phenyl CH CH CH CH Η 543 543 m CH CHCHCH η[η 2,6-Dimercaptofluoride tris(sulfonylethyl)&gt;Phenyl 544 phenyl CH CH CH CH Η 545 545 Stupid CH CH CH CH| Η | Η 546 trifluoromethyl ethoxy) phenyl 2,6~1 Ι Ι 4- 4-trimethylphenyl 2, Φ bis ^1 trifluoroanthracene Phenyl

5-53 phenyl CH CH CH CH Η 5-54 phenyl CH CH CH CH Η j: side; 4,6-bis(trifluoromethane;

Shown 112 200836629 Table 5(1)

Compound number physical properties 値i 1 H-NMR (DMS〇-d6) d 7.51-7.62(4H, m), 7.78(1 H, d, J = ?.8Hz), 7.97~8.00(2H, m), 8.05 -8O8(2H, m), 8.30(1 H, d, J = Z.4Hz), 8.37 ΊΗ, d, J = 2.0Hz), 10Λ8(1Κ s), 10.65C1H, s). &quot; 1-159 H-NMR (GDQ13) $ 3.47C3H s), 7.12-7.18 (ZH, m), 7.21-7.32: 5H, m), 7.70 (1 H, s), 7.72 (1 H, t J = 7.8 Hz), 7.82-7.83(2H, m), 8.56(1 H, s). 1-163 H-NMR(CDGi3) d 3.57(3H, s), 7.11-7.14(1 H, m), 7.40-7.41 (2H, m), 7.58 (1 H, d, J = 7.8 Hz), 7.69-7.78 (2H m), 7.91-8.02 (3H? m); 8.24 (1 H, d ( J = 4, 9 Hz), 1-264 lH-NMR(CDOl3) &amp; 7.49-7.63(4H, m), 7.70-7.73 (1 H, m), 7.76 (1H, d, J = 2OHz), 7.86-7.93 (3H, m), 7.9δ- Δ.02(3Η, m), 8.23 (1K t J = 2.0Hz). 1-265 iH-NMF^DMSO-cya 7,52-7.64(4H, m), 7.79(1H, d, J 7.8Hz ), 7.97-8.02(3H, m), 8.06-8.09(1 H, m), 8.21 (1H, d, J = 2.0Hz), 8.38 (1H, t, ϋ = 2.0Hz), 10.48(1H, s ), 10.60(1H, broad). 1-266 i H-NMFKDMSO-ds) § 7.53-7,64(4H, m), 7.81(1H, d, J two 7.8Hz), ?.B9-8.10(7H , m), δ.1δ(1Η, s), 8.27(1H, d, J = 2.0Hz), 8.41(1H, s), 10.50(1H, s), 10.75(1H, s). 1 267 !H-NMR(CDCl3) d 7.35(1H, d, J = 7.3Hz), 7.5〇-7.63(7H, m), 7.72-7.80 (3H, m), 7.89-7.92(2H, m), 8.00(1H, s), 8.05-8.10 (2H, m), 8.22(1 H, t. J = 2.0Hz). 1-303 'H- NMRCDMSO-de) $ 7.48-7.67(4H, m), 7.78(1H, dd, J = 4.4ΛΒΗΖ), 7.9t(1H, d, J = 7.8Hz), B.00-8.03(2HS m), 8.12 -8.17 (1H, m), 8.46-8.50(3H, m), 9.08(1H, dd, J = 2.0, 4.4Hz), 10.54 (1H, s), 10.84(1^ s). Bu 304 lH-NMR (DIVlS〇-d6) δ 7.33-7.40(2H, m), 7.57-7.63(2H, m), 7.68-7J3(1H? m), 7J7(1H, ddf J = 3.93.8Hz), 7.B〇 i1Ht d, J = ?.8Hz), 8.03(1 H, d, J = 7.8Hz)} B.41-B.49(3H, m), 9.08(1 H, dd, J = 1.5, 3.9Hz) , 10.70( 1H, s), 10.84(1 H; s). ' 1-305 lH-NMR(DMS〇-d6) (5 7.64(1H, t, vJ = 7.8Hz), 7.77(1H, dd, J = 3_93·8Ηζ), 7.95 (1 Hs = 7.8 Hz), 8.13 (1 H, d, J = 7.8 Hz), 8.24C2H, d, J = δ.3Ηζ), 8.39-8.50(5Η, m), 9.08 (1 H, dd, J = 1.5, 3.9 Hz), 10.84 ( 1H, si 10.85 (1 H, s).

113 200836629 Table 5 (2)

No. 3061-30 H-NMR (DMS〇-d5) 5 10.5 (1Hf s), 9.85 (1H} s), 8.36 (1H, t J=1.5 Hz), 7J8—8Ό7 (3H,m ), 7.75 (1H, d, J 7.8 Hz), 150-7.63 (4H, m). 7.42 (2H, s), Z.30 (6HS s). 1-307 H-NMR (CDC!3) ¢ 4.76-4.82 (1H, m), 7.15 (2H, s), 7.45-8.17 (10H, m), 8.30 (1H, brs). 1-308 H-NMR(CDGi3) (54.78-484 (1K m)? 7.19 (2H, s), 7.33-8.66 (10H m). 1-309 'H-NMFKDMSCHiy δ 7.53-7·63(4Η,m), 7.79(1H, d,J = 7.8Hz), 7.9B-8.02 (2H, m), 8.08 (1H, dd? J = 1.5, 7.8 Hz), 8.18 (1H, s), 8.39 (1 H, t, vi = 1.5 Hz), 10.50 (1 H, s), 10.56 ( 1 H, s). 1-310 'H-NMRiCDCIs) § ?.19-7.25(1HS m), 7.35(1H, t, ϋ = 7.8Hz)t 7.51-7,60(3Hf m), 7.76-7.78 (2H, m), 7.92(1 H, d, J = 7.8Ης), 8.19(1H, d, J = 7.8Hz), 8.34(1Η, s), B.63(1H, d, J = 16.1Hz 1-311 'H-NMRCDMSO-^) δ 7.37-7.4K2H, m), 7.56(1H, t, J = 7.8Hz), 7.79(1H,d, J = 7.8Hz), 8·06-8.14 (3H, m), 8.18(1H, s), 8.36(1 H, s), 10.51(1 H, s), 10.56(1 H, s). H rsH rs Ι^ΟΙΔ W-NMRODMSO-cy δ 7.60 (1H, d, J two 6.8Hz), 7,83(1H, d5 J _ Rs t \ #% Λ j * ti » -nr% ii \ &lt;v #-v \ rv λ ^ -ο.οπζΛ c.uyun, α, u = ι.όηζ), e. i dc.zo\4rt , m;, 5.4U (2H, d, J = 8.8Hz), 10.59OH, s), 10.81(1H? s). 1-313 'H-NMRCDMSO-dg) ά 7.53-7.64(4H, m), 7.77 (1H5 d, J = 7.8 Hz), 7.97-8.01 (3H, m), 8.07 (1 H, dd, J = 1.5, 7.8 Hz), 8.41 (1H, s\ 10.49(1H, s), 10.52 ( 1H, s). 1-314 lH-NMR (DMS〇-d5) δ 7.33-7.40 (2H, m), 7.54-7.63 (2R m), 7.68-7.72 (1 H, m), 7.78 (1 H, d, J = 7.8 Hz), 7.98 (1 Ht d, J = 8.3 Hz), 8.10 C2K s), 8.36 (1H, s), 10.62 (1K s), 10.67 (1H, s). 1-315 ^H -NMRC DMSO-de) δ 7.25-7.30 (2H, m), 7.56-7.65 (2H, m), 7.80 (1 H, df J = 8.3 Hz), 7.92-7.95 (1 Ht m), 8.10 (2H, s ), 8.32 (1H, sX 10.65(1 H, s), 11.06(1Hs), 1-316 lH-NIVlR(DMS〇-d6) δ 7.52-7.63(4HT m), 7.72(1H, d} J = 7.8 Hz), 7.98-8.01 (2H? m), 8.05-8.07(2H, m), 8.34(1 H, t J = 2.0Hz), 8.44(1 H, d, J = 2.0Hz). 10,40( 1 H. s), 10.48(1 H, s). 1-317 MS(APCI)=604(iVi-H) 1-318 MS(APGI)=604(M+1) 1-319 IVIS(APGI)= 685(M+1) 1-320 MS(APCI)=586(M+1) . ^ | Compound Number Physical Properties 値1-321 MS(APCI)=645(M+1) 1-322 MS(APGI)=685(M+1) '1-323 MS(APGD:聊(10)+1) 1-324 _S(APO!)=601(_ 1-325 IMS(APGI)=530(MM) 1-326 iMS(APCI)=63t(M+1) 1-327 MS(APGI)=642(M+1) 1-328 MS(AFCI)=542 (M+1) 1-329 MS(APOI)=610(M-fl) 1-330 MS(APC1)=547 (10)+1) 1-331 MS(APGI)=571(M+1) 1-332 IMS (APCI)=633(IV1+1) 1-333 MS(APOI)=582(M+t) 1-334 MS(APGI)=592(Mi-1) , 1-335 MS(APCI)=668(lVi +l) 114 200836629 Table 5(4) Chemical #tJ号性性値1-336 MS(APCI)=591(M+1) 1-337 MS(APCI)=641(M+1) 1-338 MS(APCI)=642 (iV!+1) 1-339 lH-NMR(DMS〇-d6) δ 7.53-7.63(4H; m), 7.75(1 H5 d, J = 7.8Hz), 7.98-B.09(3H, m) , 8.20(1 H, s), 8.37(1 H, s), 8.6ΚΊΗ, s), 10.50(1H, s)? 10.64(1H, s). 1-340 'H-NMRCDMSO-dg) $ 7.53- 7.64(4H, m), 7.70-7.73(1 H, m), 7.87(1H, d, J = δ.3Ηζ), 7.98-8O7(3H, m), δ.13-δ.17(2Η, m ), 8.38 (1 H? t J = 1.7 Hz), 10.40 (1 H, s), 10.50 (1 H, s). 1-341 MS (APCIM78(M+1) 1-342 MS(APa)=489_1 1-343 MS(APCI)=4B9(M+1) 1-344 MS(APCI)=507(M+1) 1-345 MS(APCI)=487(!Vi+1) 1-346 MS(APGI )=52KM+1) 1-3 47 MS(APGi)=534(M+D 1-348 MS(APCI)=485(M^1) 1-349 IV1S(APCI)=467(M+1) 1-^350 |MS(APOi)=4S1 (M+1)

Table 5 (5) Compound number physical properties 値 1-351 MS (APCI) = 483 (M + 1) 1 - 352 MS (APOI) = 483 (M + 1) 1-353 MS (APCI) = 543 (M+1) 1-354 MS(APGI)=503(MM) 1-355 MS(AFCI)=503(M+1) 1-356 MS(APOI)=493(y+1) 1-357 MS(APGI)=488 (IVi+1) 1-358 MS(APCI)=468(M-1) 1-359 IVIS(APCI)=488(M+1) 1-360 MS(APCI)=470(M+D 1-361 MS (APCI)=469(IV1+1) 1-362 MS(APGI)=455(iVl+l) 1-363 MS(APGI)=473〇Vt+1) 1-364 MS(APCI)=473(iVI+ 1) 1-365 'H-NMRC DMSO-ds) ά 7.53-7.73(5H,m), 7.93-8.09(6H?m), 8.38(1 HTdJ=2.0Hz), 10.4(1 H,s), 10.5( 1 Ks). 115 200836629 Table 5 (6)

- Compound No. 1-1 1-366, H-NMR (DMS〇-d6) δ 7,53-7.63(4H, m), 7.74(1H, d, =7.8HzX 7.98-8.01 (2H, m), 8.07 (1 H, dd, J = 1.5, 7.8 Hz), 8.18 (1 HT s), 8.37 (1 H, t ϋ = 1.5 Hz), 8.51 (1H, d, J = 1.5 Hz), 0.50 (1 H , s), 10.62(1 H, s). 1 1-367 H-NMR( GDC!3,) (57.00-7.06C2H, m), 7.43-7.58(2H, m), 1JZ-1J9 (3H, m ), 7.91-7.B3 (2H, m), 8.00 (1H, s), 8.26 1H, s). 1-368 H-NMR( ODCi3) ¢7.27-7.29 (1H, m), 7.54 (1H, t , J=8.3 Hz), 1.11 (IK d, J=8.3 Hz), 7.91 ClH, s)5 8.00 (1H, s), 8.21-8.34 ;5H, m), 8.91 (1H, s), 9.95 (1H , s). 1-36B H-NMR (DMS〇-d6) δ 2.32 (3K, sX 7.52-?.63 (5HTm), 7.76.; 1HfdJ=7.8Hz), 7.87 (1 8.00 (2Hfdd?J=1.5) Hz, 7.8), 8.06 (1 H, d, J = 7.8 Hz), 8.37 (1 Ks), 1Q.18 (1Ks), 10.47 (1 Ks). 1-371 lH-NMR ( DMS〇-d6) ( 5 2.32(3HTs), 7.54-7.67.72-7.77(2^1^), 7.98-8.08(3H?m)?8.37(l Ks)? 10.17( 1 Ks), 10.46(1 Ks). 1-372 ^-NM^ CDGl3) δ 2.32 (3H, s), 7.04-8.23 (14H, m). 1-373 lH-NMR(DMS〇-d6) δ 2.46(3H, s), 7.53-7.71 (6H, m ) 7.80 (1H, s), 7.90 (1 H; d, J = 7.8 Hz), 8.00-8.02 (2Η, m), 8.ID- 8.17 (2H, m), 8.38 (1H, d, J = 7.8Hz), 8.45(1H, s), 10.5K1H s), 10.52(1 H, s). 1-374 lH^NMR(DMS〇-d6 δ 2.4δ(3Η} s), 7.33-7.40(2H, m), 7.57-7.63C2H, m), 7.66-7.?3(3H, m), 7.79(1H, s), 7.88-7.9K1H , m), 8.02 (1 HT d, J = 7.8 Hz), 8.10-8.12 (1 H, m), 8.36-8.40 (2H, m), 10.540H, s), 10.68(1H, s). 375 ^-NMRC DMSO-de) δ 2.04 (2H, quint J = 7.3 Hz), 2.91 (2H, t, J = 7.3 Hz), 3.1K2H, dd, J = 7.3, 12.2 Hz), 7.40 (1H, d, ϋ = 8.8Hz), 7.51-7,67(5H, m), 7.71 (1H, d, J = 7.8Hz), 7.98-8.07 (3H m), 8.35(1H, s), 10.10(1H, s) , 10.48(1H. s). 1-376 lH-NMR(DMS〇-d6) δ 7.53-7.64(4H, m), 7.78(1 H, d? J = 7.8Hz), 7.99-8.02(2H, m ), 8.08(1 H, dd J = 2.0?7.8Hz)? 8.32 (2H s), 8.40(1 H, t J = 2.0Hz), 10.5K1H, s), 10.66(1 H, s). 1- 377 ιΗΗΜΐνΐΗ(00013) d2.33(6H,s), 7·18-7·38(5Η, m), 7.49-7.60 (5H(m), 7-72(1H, d, J=7.8Hz)f 7.87~7.96(3H, m), 8.10(1Η; s), 8.29(1 H, d, ϋ=Β.0Ηζ). 1-378 lH-NMR(CDCi3) 5Z.33(3H, s), 2.34( 6H, s), 7O4(1H, t J=B.8Hz), 7.33-7.57(8H, m)f 7.77(1 Hu d, 8.00-8.02(2Ht m), 8.14(1 H, dd, B.3Hz), 8.36(1 HT t ϋ=2.0Ηζ), 8.81(1 H, s), 9.85(1 s). 1-379 'H-NMRCCDCIs) d2.29(6H, s) , 6.67(1 H( s), 7.21 (2H, s), 7.47-7.59(6H, m), 7.7〇-7.72(2H( m)t 7.87-7.8^, m), 7.95(1 Ht d J= 7.8Hz), 8.13(1H, s), 8.25(1H.s). 1-380 !H-NMR(CDC!3) 52.32(6H, s), 7.07-7.09(1 H, m), 7.27-7.29 (1H, m)t 7·37(2Η), 138-7·57(δΗ,m), 7.73-7J8(2H, m), 7.88 (1H, d, J=8.3Hz), 8.14C1H, s) , 8.27(1H, s). 1-381 'H-NMRCCDCis) $2.34(6H, s), 7.35-7.55(1 OH, m), 7.74-7.80 (2H, m), ?.89(tHf d, J =8.3Hz), 8.11(1H, s), δ.28(1Ητ s). 116 200836629

Compound No. 物1 1-382 2 H-NMR (DIV1S〇-d6) δ 1.23-1.39 (5H, m), 1.57-1.71 (5H, m), ..45-2.5K1H, m), 7.4〇- 7.52(6Hs m), 7.66(1H, d, J = 7.8Hz)5 ?.85-7.97(3H, m), 8.23(1H, s), 10.17(1H, s), 10.37(TH s). 1 1-383 \ ( H-NyRCDMSO-c^) δ 1.20-1.40(5H, m), 1.67-1.79(5^m), L45-Z50(1H, m), 7.19(2H, d, J = 8.8Hz ), 7.47-7.6B(7H, m), ?.97-8.02(3H, m), B.29(1H, t J = ZOHz). 10.20(1H, s), 10.45 1H, s). 1- 384 H-NMR (CDCi3) δ 2·19(6Η, s), 7.00-7·09(2Η, m), 7.40-7.45 .3H, m), 7.53(1H, t, J=7.8HzX 7.63(1H , d, J=7.8Hz), 7,67(1H, s), ?.84(2HS d, J=7.8Hz), 7.95(1 H, dd, J=1.5, 7,8Hz), 8,18 (1 H, s), 5.46 (1 H, s). - 1-385 H-NMRCCDCb) 52.35 (6H? s), 7.44-7.530H, m), 7.59 (1 H, t J = 7.8 Hz), 7.72 (1H, d, J = 7.8 Hz), 7.79-?.89 (6H, m), 8.12 (1H, s), B.36 (1H, s). 1-386 H-NMR (CDCl3) d Z .33(6H, s), 4.11(1H, septet, J = 6.9Hz), 7.17C2H, s), 7.50-7.6K5H, m)f 7.7K1H, d, J = 7.8Hz), 7.87-7.90(3H , m), 8.03(1 H, s), 8.29( 1H, s). 1-387 1 H^NmRvGDClg) u 6.30 (1H, septet, J =6.8Hz), 7.01 (1H, d, J =8.8Hz )T 7.49-7.61 (4H, m), 7.68 (1H, dd, J = 1.0, 7.8 Hz), 7.88-7.91 (2H, m)t 7.96-8.01 (2Ht m), 8.26 (1Ht t, J = 1.9Hz) , 8.33 (1H, s), 8.81 (1H, d, J = 8.8 Hz). 1-389 'H-NMRCCDGls) ά 4.13 (2Η, dt, J=6.4, 14.6Hz), 7.41-7.57 (4H, m), 7.62 (1 H, d, J = 7.8 Hz), 7.99-8.01 (2H, m), 8.09 (2H, d, J = 7.3 Hz), , 8.Z2 (1Ht t J = 2.0 Hz), 9.79(1H? s). 1-390 SH-NMR (CDGi3) δ 7.50-7.6K4H, m), 7,7δ(1Η, d, J = 7.8Hz), l.miH, d, J = 7.8HzX 7 , 93(1 H, s), 7.95(1 Ht s), 8.07(1 H, s), 8.10(1H, s), 8.33(^, s). 1-391 lH~NMR (GDCI3) δ 7.44( 1H, dd, J = 4.9, 7.8Hz), ?.57(1H, t J = 7.8Hz), 7.79(1 H, d, J = 7.8Hz), 7.87-7.BK2H, m), 8.13 (1H , sX 8.23(1H, dd, J = 2.0, 7.8Hz), 8.3K1H, s), 8.42(1H, s)T 8.55(1 H, dd, J = 2.0, 4.9Hz). 1-392 'H- NMR (CDCi3) d 7.22 (1Hf dd, J = 7.8, 12.2 Hz), 7.35 (1H, t,. J = 7.8 Hz), 7.53-7.60 (2H, m), 7.77 (1H, d, J = 7.8 Hz) ), 7.90-7.92(2H, m), 8.13(1H, s)$ 8.19(1H?dt, J = 1-4, 7.8Hz), 8.34( 1H, s), 8.64(1H, d? J = 16.1 Hz). 1-393 W-NiVlR(DMSO-4) d ?·31 -7.38(2H m), 7·50-7.62(2Η,m), 7.66-7.72(4H, m) , 7.92-7.96(3Η, m), 8.Z7(1H, s), 10,61(1H, s), 10.63(1 H, s). 1-394 'H-NMRCDMSO-dg) δ 7.32-7.38 (2HT m)5 7.52-7.60C2H, m), 7.65-7.?3(2H m), 7.94(1H, d, J = 8.3Hz), 8.11(2H, d, J = 8.8Hz), 8.20- 8.23(2H(m), 8.29(1H, s), 10.67(1H, s), 11.0K1H s). 1-395 lH-NMR(CDOI3) d7.45-7.62(6H, m)T 7.69(1H, D5 J=7.8Hz), 7.B3 (2H, d, J=7.3Hz), 8.01 (2H d, J=7.3H2), 8.14(1 H, d, J=7.8Hz), 8.28 (1H, t , J=1.9Hz), 9.95(1H, s), 9.99(1H, s). 1-396 lH-NMR (CDCI3) δ 7.44-7.6K5H, m), 7.73(1H, d, J = E.3Hz ), 7.93(2H, d, J = 8.3Hz), 8.01 (2Hf d, J = 6.8Hz), 8.07-8.13(2Ht m), 8.29(1 H, si 9.97(1 H, s), 10.10(1 H, s). 1-397 'H-NMRCCDCls) d2.41(3H, s), ?.51~7.58(6H, m), 7.67(1H, d, J=6-.3HzX 7.86-7,9l (4H, m), 7.99 (1H si 8.23(1H, d, J=8.3Hz), 8.30(1 H, t J=2.0HzX 117 200836629 4 5(8)

杂性性性値T 1-398 { 1 H-NMR (CDCi3) δ 3.32 (3Η, s), 3.46 (3H, s), 6.65 (2H, d5 ϋ = ^.OHz), 6.94 (1H, d, J = 2.8 Hz), 7.07-7.12 (5H, m), 7.25 (2H, d, J =8·4Ηζ), 7_94 (2H, d. J 8.8 Hz), 9,50 (1H, s. OH) 1 1-399 H-NMR (CDC! 3) (52.4K3H, s), 7.21 (1H, dd, J = 1.0, 8.3 Hz), 7.35 (1 H, t, J = 7.3 Hz), 7.52-7.59 (4H, m), 7.69(1 H, ds J=8.3Hz), 7.86(1H, d, J=8.3Hz), 7.91(1H, s), 8.19(1H, dt, 8.3Hz), 3.23(1H , d, J=8.3Hz), 8.33(1H, t, J=2.0Hz), 8.63(1Ht d, J=15.6Hz). * 1-400 H-NMR(CDC!3) i 2,36 (3H , s), 6.63 (1H, septet, J = 6.3Hz), 6.91 (1H, s)t 7.45-7.57 (4H, m), 7.74 (1H, d, J = 7.8Hz), 8.03 (2H d, J =8.8Hz), 8.11 (1H, d, J = 8.3Hz), 8.17 (1Ht s), 8.39 (1H, t J =1.9Hz), 9.75 (1H, brs), 10.2 (1H, brs). 1- 401 'H-NMR (DMS〇-d6) (52.28 (3H, s), 7.12-7.19 (2H, m), 7.33-7.40 (2H, m), 7.52-7.63 (2H, m), 7.67-7.75 ( 2H, m), 7:94 (1HT d, J = 6.8Hz), 8.17 (1H, s), 8.33 (1H, s), 10.1 (1H( brs), 10.6 (1H, s). 1-402 lH -NMR(GDGi3) 56.31 (1H, septet J = 5.9 Ης), 7.03 (1H, d, J = 8.8 Hz), 7.20-7.25 (2H, m), 7.34-7.37 (1H, m), 7.54-7.57 (2H, mX 7.68 (1H, dt J = 7.8Hz), 8.18-8.23 (1H, m), 8.29-8.30 (2H, m) , 8,60 (1/2H, brs), 8.64 (1/2H, brs), 8.83 (1H, d, J = B.8Hz). 1-403 'H-NMRCCDCb) §6.58 (1H, septet, J =6.3Hz), 6.95 (1H, d, J = 8.8Hz), 7.45-7.58 (4Ht m), 7.70 (1H, d, J = 7.8Hz), 8.00-8.02 (2H m), 8.12 (1H, d , J = 7.8 Hz), 8.24-8.28 (2H, m), 8.56 (1H5 d, J = 2.5Ης), δ.72 (1H, brs), 9.86 (1H, s). 1-404 'H-NMRCCDCy ^6.60 (1H, septet, J = 6.3Hz)} 6.96 (1H, d, J = 9.2Hz), 7.19-7.23 (1H, m), 7.29-7.33 (1H, m), 7.46-7.54 (2H m) t 7.71 (1H, d, J = 7.8H2), 7.87-7.91 (tH, m), 8.06 (1H, d, J = 9.2Hz), 8.24-8.28 (2H, m), 8.60 (1H, d, J =2.5 Hz), 9.72 (1H, d, J = 5.3 Hz) t 10.1 (1H, s). 1-405 lH-NMR(DMS〇-d6) d 7.52-7.65(4H, m), 7.74(1 H , d, J = 7.8Hz), 7.85(1 H, d, J = 1.5Hz), 7.98-8.01 (2H, m), 8.06(1 H, dd, J = 1.5, δ.3Ηζ), 8.13(1H , d, ϋ = 1.5Hz), 8.35(1Hf t, J = 1.5Hz), 10.34 (1H, s), 10.47(1H, s). 1-406 'H-NMRiDMSQ-dg) δ 7.32-7.39(2H , m), 7.52-7.63 (2H, mX ?.67-7.74(2H, m), 7.84(1 H, s), 7.96(1 H, d, J = ?.8Hz), 8.13(1 H,. d, J = 2.0Hz), 8.30(1H, s), 10.36(1H, s), 10.64(1H, s). 1 -407 'H-NMRiDMSO-dg) δ 7.58 (1H, t J = 7.8 Hz), 7.78 (1H, d, J = 7.8 Hz), 7.85 (1H, d, J = 1.5 Hz), 8.05-8.08 (1H , m), 8.13 (1H, d, J = 1.5Hz), 8.Z1-8.24(2H} m), 8.34(1H, dt J = 1.5Hz), 8.37-8.40(2H? m), 10.37(1 H, s), 10.78(1 H, s). 118 200836629 Table 5 ί9)

Compound No.. _ ' 1 1-408 Η-NMR (DMSO-d6) δ 7.50—7.69 (7H, s), 7.97—3.04(3H, m), 8.34(1H, t, ϋ = ZOHz), 10.27( 1H, s), 10.46 (1H, s). 1-409 H-NMR (CDCl3, PPm) δ S.88-7,95 (11H, m). 1-411 H-NMR (CDCI3) ¢5 7.15- 7.20(1H, m), 7.26-7.32(^^), 7.45-7.56(2H,m), 7.69(11^d, d = 7.8hk), 7.89(1 H,d,J = 2·0Ηζ), 7·92 ;1H, d, J = 2.0Hz), 7.99(1 H, dd, J = 2.0, 7.8Hz), 8.10-8.15(1 H{ m), 8.1B(1H, s), 8.22(1 H, s), 8.64 (1 H, d, ϋ = 15.1 Hz). 1-412 H-NMR (DMS 〇-d6) δ 7.59 (1H, t, J = 7.8 Hz), 7.B2 (1H, d , J = 7.8Hz), 8.07-8.10(2H, m), 8.23(2H, d5 J = 8.8Hz), 8.34-8.40 (4H, m), 10.69(1 K s), 10.78(1 H, s) 1-413 'H-NMRCCDCIs) δ 7.4〇-7.45(3H, m), 7.50-7.54(1 H, m), 7.64(1H, d, J = 7.8Hz), 7.75(1 H, d, J = 1.5Hz), 7.81-7.85(3H, m), 8.07(1 H, d, J = 7.8Hz), 8.19(1H, s), 8.Z5(1H, s), 8.54(1H, s). 1-414 'H-NMRC DMSO-ds) δ 7.31-7.3B (2H, m), 7.51-7.61 (2H, m), 7.66-7,72 (2H, m), 7.94-7.97 (2H, m), 8.28(1 H, d, J = 2.4Hz), 8,31 (1H d, J = 2.4Hz), 10.42(1 H, s), 10.63C1H, s). 1-415 /H-NMRfDMSO-cQ δ 7.51-7·Pan (4H, m), 7·72 (1Η, d, J = 7.8 Ηζ), 7.96-8.00 (3H5 m), 8.05 (1 H( dd , J = 1.5, 7.8 Hz), 8.32 (1 H, d, ϋ = 2.0 Hz), 8.33 (1H, d, J = 2.0 Hz), 10.40 (1H, s). 10.46(1H, s). 1- 416 'H-NMRC DMSO-^) δ 7.33-7.40 (2H, m), 7.54-7.63 (2H, m), 7.67-7.72 (1H, m), 7.79 (1H, d, J = ?.8Hz), 7.98(1H, d, J = 7.8Hz), 8.13 (1H, d, J = 1.5Hz)? 8.20(1K d, ϋ = 1.5Hz), 8.35(1H, s), 10.62 (1H, s), 10.67 (IH, s). 1-417 ^-NMRC DMSO-dg) d 7.51-7.62 (4H, m), 7.71 (1H, d, J = 7.8 Hz), 7.97-8.06 (4H; m), 8.3〇-8.34 (2H, m), 10.35 (1H, s\ 10.46(tH s). 1-418 'H-NMR (CDC! 3t ppm) (5 6.86-6.98 (3H, m), 7.18 (2H, t J=7.8 Hz), 7.33-7.45 (2H, m), 7.58 (1H, t, J=7.8 Hz), 7.B5-8.11 (3H, m). 1-419 lH NMR (DMSO-de ) (5 7.52-7.85 (7.99-8.06(3H,m), B.15-8.19(1 H,m),8.34(1 H,s), 10.4(1 Hrs).10.5(1 KsX 1-420 l|H-NMR(DMSCHd5 , ppm) δ7·518·05(11Η,Γπ),8·34(1Η,υ=1·5), 10.2(1H,s),10.5Cias). 1-421^-NMRiGDGls) δ1Λ4 (3H, s ), 7.16-7.21 (1H, m), 7.44-7.57 (5H, m), 7.66-7.72 (2H, m), 7.83 (1HS d, J =B.3Hz), 7.92-7.95 (2H, m), 8.25 (1H d, J = 8.8Hz), 8.31. (1H, s). 1-422 'H-NMRCDMSO-de) &lt;5 0.75C3H, t J = 7.3 Hz), 1.19 (3H, d, ϋ = 6.8 Hz)? l.51-l.59 (ZH, m), 3.02-3.11 (1H? m) (7.5〇-7.63 (7K m), 7.73 (1H, d, J = 7.8Hz), 7.99-8.07(3H, m), 8.36(1H s), 10.17(1H, s), 10.48(1 H, s). 1-423 ^H-NMRC CDC !3, ppm) a7.48-7.69(7HTm), 7.88-8.00(4H?m), 8.23(1 H.tJ=2.0HzX 8.61(1H,br.s), 8.76(1 H,drJ=8.8Hz ). 119 200836629 Table 5. (10)

—合ΐΐ号— wr±M 1 1-424 H-NMR(DMS〇-d6) ¢5 7.33-7.40(2H, m), 7.52-7.63(2H, m), 7.66-L73(4H,m) , 7·95 (1Η, d, J 2 7.8 Hz), 8.05 (2H, d, J = 8.8 Hz), 8.30 1H, s), 10.67 (2H, s). 1-425 · H-NMR (CDCt3) (5 3.21(3K s)5 3.41(3H, s), 7.46-7.?5(6H, m), 7.86-7.93(4H, m), 8.D0(1H, s), 8ΌΚ1Η, s), 8.40(1H, s). 1-426 H-NMR(CDCI3) (5 3.2K3H, s)5 3.41(3H, s), 7.51-7.57(2H, m), -7.64 (1 H, d, J = 8.8 Hz) 5 7.89 (2H, d, J = 7.8 Hz), 7.93 (1 H, s), 8.02; 2H, d, J = 7.8 Hz), 8.08 (1K d, J = 8.3 Hz), 8.33-8.40 (3H, m). 1-427 H-NMR (DMS〇-d6) δ 7.53-7.63 (4H, m), 7.79 (1H5 d, J = 7.8 Hz), 7.98-8ΌΚ2Η, m), 8.06-8.09 ( 1H m), 8.23(2HS s), 8.39(1H, s), 10.50(1 as)? 10.62(1 H, s). 1-428 lH-NlVlR(DlVlS〇-d6) δ 7.33-7.40(2H, m), 7.54~7.63(2H, m), 7.68-7.72(1 H, m), 7.79(1 H, d, J = 7.8Hz), 7.98(1^d, J = 8.3Hz), 8.23(2H , s), 8.35(1 H, s), 10.64(1 H, s), 10.67(1 H, s). 1-429 ^-NM^DMSO-dg) d 7.25-7;30(2H, m) 7.56-7.65(2H, m), 7.81(1 H, d, J = 7.8Hz), 7.94(1 H, d, J = 8.3Hz), 8.23(2H, s), 8 .31 (1H, s), 10.67 (1 H( s)5 11.06(1 H, s). 1-430 lH-NMR (CDC! 3) (5 4.4 Ί (2H, t5 d =11.7Hz), 7 ·02 (2H, s), 7.50-7.64 (5H, m), 7.73-7.74 (1H, m), 7.89-7.90 (2H, m), 7.95-7.97 (1H, m), 8.04 (1H, s) , 8.26 (1H, s). 1-431 ]H-NMR(GDGI3) (54.43 (2H, t, J =1Z.0Hz), 7.05 (2H, s), 7.20-8.21 (8H, m), 8.30 ( 1H, s), 8.61-8.65 (1H, m). 1-432 ^-NMRCGDCls) ¢ 2.33 (3H, s)f 4.38 (2H, q, ϋ =8.3Hz), δ.ΒΖ (1H, dd, J Two 2.9, 8.8 Hz), 7.44 - 7.57 (7H, m), 7.70 (1H, cU two 7.8 Hz), 7.99 (1H, dd, J = 7.8, 1.5 Hz), 8.10 (1H, d, J = 7.8H2 ), 8.34 (1H, s), 8.73 (1H, brs), 9.86 (1H, brs). 1-433 lH-N!VIR(CDCI3) 54.43 (2H,t,J 2:11), 7·04 (2H, s), 7.40—7.44 (1H m), 7.52-7.56 (1H, m)t 7.66 (1H, brs), 7.76-7.78 (1H, m), 7.91-7.93 (1H, m), 8.19- 8.24 (2H, m), 8.45 (1H, s), δ.52-8.54 (1H, m). 1-434 'H-NMRCCDCy 52.34(6H, s), 7.47-?.57(〇H m), 7.68(1Hf s\ 7.74 (1H, d, J=7.8Hz), ?.98-B.00(2H, m), 8.12(1H, d, J=7.8Hz), 8.33 (1H, s), 8.64 (1H, s), 9,63(1H, s). 1-435 'H-NMRCCDCis) ά 2.35(6H, s), 3.51 (3H , s), 7.32 (2H, sX 7.50-7.62(4H, m), 7.66(1 H, s), 7.72(1 H, d, J = 7.8Hz), 7.86-7.90(3H, m), 8.04( 1 H, s), 8.31 (1H, d, J = 2.0 Hz). 1-436 ^-NMRiCDCls) δ 2.37 (6H, s), 3.52 (3H, s), 7.23 (1H, dd, J = 7.8, 12.2Hz), 7.33(2H, s), 7.35(1 H, t, J = 7.8Hz), 7.52-7.60(2H, m), 7.63(1 H, s), 7.74(1 H, d, J = 7.8 Hz), 7.87 (1 H, d, J = 7.8 Hz), 8.19 (1H dt J = 1.4, 7.8 Hz) s 8.34 (1H, s), 8.64 (1H, d, J = 16.6Hz). 1- 437 ^-NMRCDMSO^-dg) d 7.53-7.63(^^), 7.75-7.78(1 HTm), 7.83(2HTs), 7.99-8.08(3H,m) melon 37 (1 Ks), 10.4 (1 Kb" ·), 10.5(1 H,brJ. 1-438 !H-NMR( GDCi3) ¢52.38(3^9), 7.09-7.12(2Hfm), 7.48-7.57(4H?m), 7.70(1H,cW= 8.3 Hz) 5 7.76 (1H, &lt; W = 8.3 Hz), 7.99 - 8.01 (2H, m), 8.10 (1H, d, | ϋ = 8.3 ΗΣ), 8.35 (1HdJ = 2.0 Hz), 8.67 (1 Hrs ), 9.74 (1 Ks). 120 200836629 Table 5 (11)

A compound numbering property 値L 1-439- {H-NMR (GDG!3) δ 6.49 (1 H, d, J = 9,3 Hz), 7.5.1-7.62 (6H, m)f L00 (1Ht d, ϋ = 7.3 Hz), 8.12 (1K d, J = 7.3 Hz), 8.45 (1Hf d, J = 5.3 Hz), 8.B4 (1H, s), 9.24 (1H, s), 10.49 (1K s). 1L55(1H.s). 1-440 MS(APCI)=352(M+1) 1-441 H-NiVIRCCDCIs) δΖ.44 (3H, s), 7.31-7.59 (5H, m), 7.73 (1H, d, J = 7.8 Hz), 7.97 (2H, dd, J = 1.5, 7.8 Hz), 8.06 (1H, d? J = 7.8 Hz), 8.36 (1HS t J = 1.9 Hz), 8.94 (1H, s) , 9.03 (1H, s), 9.32 (1H, s). 1-442 H-NMR(GDCi3) ¢7.46-7.68 (4H, m), 7.77 (1H, d, ϋ =7.9Hz), 8Ό0-B. 02 (2HS m), 8.09 (1H, d, ϋ =2.0Hz), B.17 (1H, dd, J = 8.3, 1.5Hz), 8.38 (1H, t, J = 1.5Hz), 8.67 (1K d , J = 2.0Hz), 10.2 (1H, brs), 10.4 (1H, brs). 1-443 'H-NIVlR(DIVIS〇-d6) d 2.23(3H, d, J = 2.9Hz), 3.81 (3Ht s), 7.53-7.63(4H, m), 7J5(1H, d, J = 7.3Hz), Β.01-8.06(3Η( m), 8.37(1 H, s), 10.29(1 H, s) , 10.49(1 H, s). 1-444 ^-NMRCDMSO-ds) d 2.23(3H, d, J = 2.0Hz), 3.81 (3H, s), 7.33-7.40(2H, m), 7.53-7.63 (2H, m), 7.67-7.76(2H, m), 7.95(1 Hf d, J = 7.8Hz), 8.33(1 H, s)t 1 0.30(1 H, s), 10.66(1 H, s). 1-445 lH^MR(GD0!3) §2.36 (3H, s), 7.25 (1H, s)f, 7.47-7.57 (4H, m ), 7.77 C1H, d, J = 7.8ΗςΧ 7.99 (2H, dd, J = 1.5, 8.7Hz), 8.14 (1H, dd, J = 1.5, 7.8Hz), 8.38 (1H, t, J = 1.5Hz) , 9.28 (1H, brs), 9.82 (1H; brs). 1-446 lH-NMR (DMSO~d6) δ 2.29 (6H, s), 7.51-7.63 (6H, m)t 7.76 (1 H, d, J = 7.8 Hz), 7.98-8 ΌΚ 2 Η m), 8.05 (1H, dd, J = 2.0, 7.8 Hz), 8.37 (1H, t J = 2.0 Hz), 10.02 (1 H, s), 10.47 (1 Hs s 1-447 lH-NMR (DMS〇-d6) δ Z28(6H, s), 7.33~7.40(2H, m)t 7.53(2H, s), 7.54-7.77(4H, m)f 7.95(1 H, d, J = 8.3 Hz), 8.33(1 H, s), 10.03(1 H, s)t 10.64(1H, s). 1-448 ^-NMRCGDCls) δ4.67(2Η, d, J= 5.9H2), 7.4〇-7.65(9H, m), 7.97-8.03(4H, m), 8.27(1 H, t J=2.0Hz), 9.73(1 H, s). 1-449 'H-NMRCGDCg 54.88(2H, d, J=5.8Hz), 7.43-7.65(9H m), 7.98-8.00(3H, m)t 8.04(1 H, d, J=8.2Hz), 8.24(1 H, d, J =1.9Hz)f 9.68 (1H, s). 1-450 'H-NMRCCDCIs) δ4.83(2Η, d, J=5.8Hz), 6.58(1 H, brs), 7.40-7.69 (9H, mX 7.86 -7.88(ZH, m), 7.92(1H, d, J=8.3Hz), 7.97(1 H, s), 8.05 (1H, tf J=2.0Hz). 1-451 MS(APGI)=376(M+1) 1-452 lH-NMR(GDC!3) δ4.7δ(2Η5 d, ϋ=5.9Ηζ), 6.82(1H, brs), 7.45-7.63 (5H, m) , 7.79(2H, s), 7.80(2H, s), 7.87(2H, d, J=7.4Hz), 8.00(1 H, s), 8.21 (1H, t J=2.0Hz). 1-453 ' H-NIVlR(DIV!S〇-d6) d 2.19(6H, s), 7.24(2H, s), 7.49-?.63(4H, m), 7.73-7.7δ(1Η, m)t 7.98-B .05(3H, m\ 8.35(1H, t J = 1.5Hz), 9.83 (1H s), 10.46(1 H,s). 121 200836629 -- Physical properties -- T 1-454 : t H-NMR ( DMS〇-d6) &lt;52.19(6H, s), 7.37(2H;s), 7.49-7.63(4H, m)( ?.74(1H( d, ϋ =7.8Hz)f 7.98- 8.05C3H, m ), 8.35 (1 H, t, J = 2.0 Hz), L82 (1H, s), 10.44 (1 HT s). • i 1-455 H-NMR (CDCi3) ^ 2.24 (6H, 4 7.43-7.57 ( 6H, m)5 7.74 (1H, d, J = 7.3 Hz), 8.01 (2H, d? J = 8.3 Ηζ) 5 8.12 (1H, d, J = 8.3 Hz), 8.36 1H brs), 9.32 (1H, Brs), 10.1 (1H, brs). 1-456 H-NMR (CDCl3) δ 2.19(6H, s)t 6.97-?.04(2H, m), 7.39-7.49; 4H, m), 7.55(1) H, brs), 7.69 (1 H d, J = 8.3 Hz), 7.79 (1 Hf dd, J = 8.3, 1.5 Hz), 8.04 (1 H, brs), 8.24 (1 H, t J = 1.5 Hz) 1-457 H-NMR (DMS〇-d6) &lt;5 7.50-7.62 (5H, m), 7.67-7.69 (1 H, m), 7.83 :1H, dd,J = 2.4, 8.3 Hz), 7-88 (1H, d, J 2.4 Hz), 7.97-δ·04 (3Η, m), δ.33 (1 H, t, J = 2.0 Hz), 10.20 (1 H, s), 10.46(1 H, s). • • 1-458 H-NMR (DMS〇-d6) δ ?.51-7.64(5H, m), 7.72(1H, d, J = 7.8Hz) , 7.82(1 H, d, J = 6.8HzX 7.94-8.00(3HT m), 8.03-8.06(1 H, m), 8.33 (1H, s), Ί0.33ΟΗ, s), 10.46(1K s). 1-459 lH-NMR (DMS〇-d6) ¢ 7.45-7.63 (6H, m), 7.91-8.01 (4H, m), 8.16 (1H, d, J = 8.3 Hz), 8.32 (1H, t J = 1.5Hz), 8.65 (1H, brs), 10.0 (1H, brs). 1-460 'H-NIVIR(DMS〇-d6) d2.21 (3H, s), 7.51-7.63 (4H, m), 7.72 -7.76 (2H, m), 7.80 (1H, d, J = 1.9Ηζλ 7.99 (2H, d, J = 8.8Hz), 8.05 (1H, d, J = 8.8Hz), 8.36 (1H, brs), 10.0 (1H, brs), 10.5 (1H, brs). 1-461 lH-NMR(CDCi3) ^2.27 (6H, s), 7.08-7.15 (3H, m), 7.48-7.60 (5H m), 7.69 (1H , d, ϋ =7.8Hz), 7.B6-7.89 (2H, m), 7.95-7.97 (1H, m), 8.11 (1H, brs), 8.22 (IK s). 1-462 ^-NMRCCDCis) 53.87 (3H, s), 7.47-7.59 (3H, m), 7.72 (1H, d, J = 2.9Hz), 7.78 (tH, d, J = 7.8Hz), 7.99-8.03 (2H, m), 8.12 ( 1H, df J =7.8Hz), 8.46 (1H, s), 10.3 (1H, brs), 10.4 (1H, brs 1-463 'H-NMmDIVISO-cg d 7.53-7·64(4Η, m), 7.77(1H, d,J = 8.3hk), 7.98-8.01 (2H, m), 8.07(1 H, dd , J = 1.5, 8.3 Hz), 8.43 (1 H, 1; J = 1.5 Hz), 10.5 K1H s), 10.97 (1H, s). 1-464 'H-NMRC DMSO-d^ δ 7.53-7.64 (4Ht m), 7.75(1 H, d, J = 8.3Hz), ?.99-8.08(3H, m), 8.41(1H, s), 10.50(1H, s), 10.59(1H, s). 1- 465 'H-NMRC DMSO-dg) δ ?.33-7.44 (4H, m), 7.51-7.63 (2Hf m), 7.67-7.74 (2H, m), 7.95 (1H, d, J = 7.8 Hz), 8.32 (1H, s), 10.40(1^ s\ 10.65 (1H, s). 1-466 ^H-!MMR(DMS〇-cl6) δ 7.33-7.40(2H, m), 7.52-7.63(2H, m ), 7.68-7.7K2H, m), 7.74 (2H, d, J = 8.8Hz), 7.96 (1H, d, J = 7.8Hz), 8.02 (2H, d, J = 8.8Hz), 8.30(1H, s), 10.67(2H, s). 1-467 1H-NMR(DMS0-d6) 0' 7.33-7.40C2H, m), 7.53-7.63 (2H, m), 7.68-7.72 (1 H, m), 7.77(1 H, d,d = 7·8Ηζ), 7·83(1Η, dd, J = 2.0, 8.3HzX 7.89(1H, d, J = 8.3Hz), 7.97(1H, d, J = 7.8Hz ), 8.13 (1H, s), 8.36(1H, s), 10.26(1H, s), 10.68(1H s). 1-468 'H-NMR(DMS〇-d6) 5 ?.53-7.63(4H , m)t 7.78(1H d, J = 7.8Hz), 7.98-8.0K2H, m), 8.06-8.07(1H, m), 8.13(1H, d, J = 2.0Hz ), 8.20 (1H, d, J = 2.0Hz), 8.39(1H, d, J ^ 2.0Hz), 10.50(1H, s), 10.60(1H, s). 122 200836629Table 5(13)

働 —— -————___________ 1-469 · H-NMR (DMS〇-d6) δ 7.2?-7.39(2H, m), ?.51~7.63(4Η, m), 7.68-L77(3H, m ), 7.81 (1H, d, J = 7.8 Hz), 7.95-7.98 (1H, m), 8.31 (1H, s), 10.19 OH, s), 10.66 (1H, sX 1 Ί-470 H-NMR (DMS) 〇-d6) δ 7.51-7.62(^, m), 7.71〇H d, J = 7.8Hz), d, J = 2.4HzX 7.97-8,06(3H, m), 8_20(1H d, J : 2.4 Hz), B.33(1H, t J = 2.0Hz), 10.37(1 H, s), 10.46(1 H, s). 1-471 H-NMR(DMS〇-d6) $ 1.26(6H, d , J = 6.8Hz), 3.08(1 H, septet, J = 6.8Hz), 7.52-7.63(4H, m), 7.69-7.74C2H, m), 7.98-8.01 (3H, m), 8.06 [1H, Dd, J = 1.5, 7.8 Hz), 8.32 (1H, t J = 1.5 Hz), 10.28 (1H, s), 10.47 [1H, s)· 1-472 lH-NMR (DMS〇-d6) δ 1.26 ( 6Ht d, J = 6.8Hz), 3.08(1 H, septet, J = 6.8Hz), 7.32-7.39(2H, m), 7.51&gt;7.63(2H, m), 7.67-7.73(3H, m), 7.96~7.98(2H, m), 8.27(1H, si 10.30(1H, s), 10.65(1H, s). 1-473 ]H-NMR(DMS〇-d6) δ 7.44-8.06(13H, m) , 10.39(1H, s), 10.48 (1K s). 1-474 'H-NMR (DMS〇-d6) &lt;5 2.42(3Ht s), 7.53-7.64(4H, m), 7.75(1H, d , J = 7.8Hz), 7.83(1 H, d, J = 7.8Hz), 8.00(2H, d, J = 6. 8Hz), 8.06 (1H d, J = B.3Hz), 8.13(1 H, d, J = B.3Hz), 8.21(1 H, s), 8.40(1 H, s), 10.17(1 H, s), 10.50(1 H, s). 1-475 MS(APGI)=385(M+1) 1-4-76 MS(APCI)=488(M+1) 1-477 'H-NMR (CDCi3 6 3.35(6H, s), 7.51-7.6K5H, m), 7.77(1H, t, J = 8.8Hz), 8.00(2H, d, J = 7.8Hz), 8.05-8.07(2H, m), 8.40(1 H, s), 10.14(1H.s), 10.48(1H, s). 1-478 'H-NMRCDMSO-de) δ 7.48-7.56(3K m), 7.63-7.67(2^ m), 7.94-7.99(4H, m), 8.22(1 H. s), 9.03(1 H s), 9.46(2H, s). 479 lH-NMR (CDCl3) δ 7.53-7.62C5K m), 7.76(1 H, d, J = 7.8 Hz), 8.00 (2H, d, ϋ = 7.3 Hz), 8.08 (1 K d, J = 7.8 Hz), 8.42 (1 H, s), 8.95 (1 H, sX 9.30 ( 1H, s), 10.50C1H, s). 1-480 ]H-NMR(CDCi3, ppm) δ 1.36(9H!s)f2.34(3HTs)t6.92-*6.95(2Hfm), 7.49-8.22( 12H,m). 1-481 iHHMMRCDMSOdP δ 2.50(3H,s), 7.14(1H,dcW=2.5,8,8H2:), 7.21(1H,d,J=2.4HzX 7.41(1H,d,J=8.8 HzX 7.50-7.75(8H,m)f 7.97-8.14(5H,m), 8.34(1H,s), 9.98(1HTs), 10.47(lH.s). 1-482 'H-NMRCDMSO-de) δ 2.28 (3H,s), 7.31(1 Hts), 7.50-8.16(14H,mX 8.38(1Hts), 10.09(1KsX 10.48(1H,s). Ί —48^ sH -NMR (DMS 〇-cl6) δ 2.15 (3H, s), 6.69 (1H, dTJ = 2.4 Hz X 6.78 (1 H, d, J = 2.4H2X 7.4B-7.63 (4Hm), 7.74 (1 H, d , J=8.8Hz)? 7.98-8.05(3H,mX 8.32(1 H,tJ=2.4Hz), 9.77(1H,s), 9.82(1Ks), 10.4(1H.s). 123 200836629 Table 5(14 ) _ number - object theory - 1-- 1-484 H-NMR ( DMS 〇 - d6) δ 2.16 (3H, s), 6.72 (1 H, d, J = 2.4 Hz), 3.94 (1 HrdfJ= 2.4 Hz), 7.5〇-7.63(4H,m), 7.74(1 H,d,J=8.3Hz), 7.98-B.05(3H,m), 8_32(1H,s), 9,79(1Hs ), 9.81(1H,s), 10.4(1H,s)· 1-485 H-NMR(CDCl3) (5 Z.29(3H,s), 2.48(3Ks), 6.94(1 ΗΛϋ=2.9Ηζ), 7.14(tH,d,J=2.9H2), 7.36(2HTd,J=8.3Hz), 7.51-7.61 (5H,m), 7.71-7.77(3H?m), 7.88-7.92(3Hm), 7.99(1 Rbr.s), 8.28(1 Hfs). 1-486 'H-NMR (CDCi3) δ 1.82-1.89 (4H, m), 3.30-3.60 (7H? m), 7.23-7.30 (5H, m), 7.44 (2H, s)T 7.76 (2H, d, J=4.9 Hz), 7.87 (2H, d, J=6.4 Hz), 10.4 (1H, s). 1-4B7 'H-NMR (CDCI3t ppm) δ 1.41 (3H, t, J=7.3 Hz), 3.57 (3H, s), 4.41 (2H q, J=7.3 Hz), 7.20-7.34 (6H, m), 7.40 (2H, t J=7.8 Hz), 7.61 (1H, d, J=2.0 Hz), 7.71 (1H, d, J=7.8 Hz)t 8.27 (2H, s). 1-488 'H-NIVIR (DMS〇-d6) δ 7.51-7.59 (3H, m), 7.62 (2H, s), 7.78 (1H, d, J=7.8 Hz), 7.86 (1H, d, J=7.8 Hz), 7.89-7.91 (2H, m), 8.05 (2H, d, J = 7.3 Hz), 8.38 (1H, s), 9.47 (1H, s). 1-489 'H-NMRCCDCb, ppm) δ 2.92 (4H, s), 7.48 (2H, s), 7.48-7.59 (4H, m), 7.76 (1H, d, J=7.8 Hz), 7.85 (1H, s), 7.90 (2H, d, J=7.8 Hz), 7.96 (IK d, J=7.8 Hz) , 8.03 (1H s), 8.24 (1H, s). 1-4B0 'H-NMR (CDGI3i ppm) (5 7.49-B.02 (15H, m), 8.10 (1H, d, J=7.3 Hz), 8.22 (1H, s). 1-491 MS(APCI)=374(M+1) .1-492 IVlS(APCI)=374(M+l) 1-493 MS(APCI)=408(M+1) 1-494 MS(APGI)=402(MH) 1-495 MS(APCI)=404(M+1) 1-496 MS(APGI)=392(M+1) 1-497 'H-NMRCDlVlSO-de) δ 7.52-7.62 (5Ht m), 7.80 (1H, d, J = 6.8Hz), 7.97-8.00 (2H, m)} 8.05 (1H, d} J =7-8Hz), 8.32 (1H, d, J = 5.9 Hz), 8.38 (1H, s), 8.92 (1H, t, J = 3.9 HzX 10.48-10.54 (2H, m). 1-498 'H-NMR (DMSO~d6) δ 7.51-7.59 (3H, m), 7.80-7.85 (1Hf m), 7.92-7.96 (1Ht m), 8.09 (1H, dd, J = 7.3, 2.0Hz), 8.21 (1H, dd, J = 7.3, 2.0Hz), 8.40 (1H , brs), 8.54 (2H, d, J ^.OHz), 10.38 (1H, s), 10.86 (1H, s).

Table 5 (15) Compound number Physical properties ^ 1-^: 9 MS (APOI) = 368 (M + 1) 1-500 MS (APCI) = 36B (M + t) 1 A fine MS (APCi) = 368 (M +1) 1-502 MS(APCI)=42t(M+l) 1-503 MS(APC1)=400(10)+1) 1-504 MS(APCI)=338(M+1) 1-505 MS(APCI) =383(M+1) 1-506 MS(APGI)=405(M+i) 1-507 MS(APCI)=419(M+1) 1-508 MS(APCI)=375(M+1) 1 -509 MS(APGI)=375 (10)+1) 1-510 MS(APGI)=356(MH) 1-511 MS(AP0I)=347(1V1+1) 1-512 MS(APGI)=367(M+ 1) 1 1-513 MS(APCI)=354(IVl+l) 124 200836629

Table 5ilQ

-3⁄4 杂号号 - - Property 値 - 1-514 1 VIS(APCI)=402(M+1) 1-ST5 ^S(APOI)=338(M+1) 1-516 ^S(APCI)=335 (M+1) 1-517 (H-NMR (CDCi3, ppm) d 2.72 (3H, s), 7.48-8.01 (12H, m), 8.41 :1H, d, J=2.0 Hz). 1-518 H -NMRCCDCl3) δ 2.56 (6H, s), 7.13-7.18 (1H, m), 7.24-7.31 : 2H, m), 7.50-7.57 (2K m), 7.94 (2Ht d, J =7.3Hz), 8.21 ( 1H, d, J = 7.3 Hz), 8.50 (1H, s), 9.43 (1H, d, J = 8.8 Hz). 1-519 H-NMR (CDGl3) $3.56 (3H, s), 4,05 (6H , s), 7.09 (1H, s), 7.14 (1H, t J = 4.9Hz), 7.35 (1H, d, J = 5.3Hz), 7.56 (1H, df J =1.5Hz), 7.58 (1H, d , J = 1.5 Hz), 7.65 (1H, d, J = 5.9 Hz), 7.73 (1H, s), 8.27 (1H, t J = 1.5 Hz). 1-520 ^H-NMRCCDCls) ¢3.53 (3H, s), 4.03 (6H, s), 7.16-7.27 (5H, m), 7.28-7.35 (4H, m), 7.66 (*1H, d, J = 1.46Hz). 1-521 ^-NMRiCDCIs-DMSO- Da) d 7.43-7.53 (5H, m), 7.70 (1H, d, ϋ = 7.8Hz), 7.99 (1HT d, J = 6.8Hz), 8.17 (1H, d, J = 7.8Hz), 8.28 (1H , sX 9.21 (1H, br.sX 9.70 (1H, br.s.). 1-522 ^H-NrvIRiCDOIg-DrvISO-dg) u 7.13~?.32 (2H, m), 7.45-7.55 (2H, rn ), 7.75 (1H, t J = 3.9Hz), 7.86-7.90 (1Ht m), 7.94-B.12 (1H, mX 8.25 (1H s), 9.73 (1H, d, J = 6.3 Hz), 9.86 (1H, br.s.). 1-523 lH-NMR(GDGl3) (52.56 (6H , s), 7.13-7.1B (1H, m), 7.24-7.31 (2H, m), 7.50-7.57 (2K m), 7.94 (2H, d, J = 7.3 Hz) t 8.21 (1H, d, J = 7.3 Hz), 8.50 (1H, s), 9.43 (1H, df J = δ.8Ηζλ 1-524 'H-NMRiCDGls-DMSO-dg) δΖΜ (3H, d, J = 4.4 Hz), 3.51 (3H, s), 7.20-7.43 (8H, m), 7.74-7.79 (2H, m), 7.99-8.02 (2H, m), 8.75 (1H, d, J=44Hz), 11.9 (1H, s). 1- 525 'H-NMR (CDCl3~DMS〇-d5) δ 1.25 (6H, d, J = 6.8 Hz), 3.53 (3H, s), 4.22 (1H, sep., J = 7.8 Hz), 6.19 (1H, d, J = 7.8 Hz), 7.13-7.27 (3H, m), 7.29-7.34 (5H, m), 7.72-7.75 (2H, m), 7.81 (1H, t, J = 2.0Hz), 8.01 (1H Dd, J = 1.5, 6.8 Hz), 11.21 (1H, s). 1-526 lH-NMR(GDGl3-DMS〇-d6) ¢6.82 (1Ht q., J =2.0, 7.2, 6.3, ZOHzX 7.48-7.62 (5H, m), 7.85 (1H, dd, J = 1.5t 6.8, l.OHz), 8.00 (2H, m), 8.25-8.28 (ΊΗ, m), 8.34-8.52 (3H, m)t 8.64 ( 1H, br.s.), 10.28 (1HT br.s·)· 1-527 'H-NIVIRCCDCIs-DIVISO-dg) δ 3.53 (3H, s\ 7.20-7.27 (3H, m), 7.32 (3H, t , J = 7.3Hz), 7.44 (1H, t, J = 7.8Hz ), 7.54 (1H, t, J = 7.8 Hz), 7.90-7.91 (tH, m), 7.95-7.98 (1H, m), 8.07-8.13 (3H, m). 1-528 'H-NMRCODCis-DMSO -dei ¢ 3.46 (3H, s), 7.22-7.31 (4H, m), 7.32-7.34 (2H, m), 7.47-7.53 (2H, t J = 7.8Ης), 8.00-8.03 (2H, mX 8.21 ( 1H, d, ϋ =2.0Hz), 8.43 (1H, t J =1.5Hz). 125 200836629 Table 5(17)

_ Compound No. 1 - Physical Properties - I 1-529 - H-NMR (CDCl3-DMS〇-d6) 53.43 (3H, s), 7.Z1-7.29 (4H, m), 7.30-7.32 (2H , m), 7.44-7.49 (2H, m), 7.98-8.00 (2H, m), 8.05 ΊΗ, d, ϋ =2.0Hz), 8.19 (1H, t J =2.4, 1.0Hz). 1-530 H -NMR (GDC! 3, ppm) $ 3.11 (3H, s), 3.56 (3H, s), 7.21-7.34 :6H, m), 7.42 (1H, t J=8.3 Hz), 7.60 (1H, brs) , 7.63 (1H, brs), 7.71 (1K dd, J=1.5 Hz, J=8.3 Hz), 7.96 (2K s). 1-531 H-NMR (GDCI3) δ 2.07 (3H, s), 2.18 (3H , s), 3.19-3.50 (3H, m), 6.09-7.84 (8H, m), 8.00 (2H, s). 1-532 'H-NMR (DMS〇-d6) δ 2.50 (3H, s), 3.39 (3H, s), 3.42 (3H, s), 6.30-7.30 (8H, m), 7.72 (2H s). 1-533 'H-NMR (DMS〇-d6) δ 3.17 (3H, s), 3.22 (3H, s), 3.72 (3H, s\ -6.52-7.76 (11H, m), 1-534 Ή-NMR (CDCi3) δ 1.02(3H, t, J = 7.3Hz), 1.65(2H, tq , J = 7.3, 7.3Hz), 2.87(2H, t, ϋ = 7.3Hz), 7.Z1(1H, dd, ϋ = 8.3, 11.7Hz), 7.31-7.34(3H, m), 7.49(1 H , t, J = 8.3Hz), 7.53-7.57(1 H, m), 7.69-7.74 (3H,m), 8.04-8.08(2H, m), 8.14(1H,s),9.11(1H,d, J = 11.7Hz), 9.27(1 H, s). 1-535 Ή-N MR (CDCI3) δ 1.05 (3H, %ό = 7~3Hz), 1.66-1.79(2H, m), 2·72-2·86(2Η, m), 7.22(1H, t J = 8.3Hz), 7.3 7.340H, m), 7.50 (1H, t J = 8.3Hz), 7.55-7.56(1H, m), 7.61(2H, d, J = 8.8Hz), 7.75 (1H d, J = 8.3Hz) f 7.98(2H, df J = 8.8Hz), 8.06-8.08(2H, m)( 8.17 (IK s), 9.06(1H, d, J = 11.7Hz), 9.65(1 H, s)., 1- 536 lH-N!VlR (CDGI3) δ 1.06(3H, t, J = 7.3Hz), 1.72(2H, tq, J = 7.3, 7.3Hz), 2.93(2H, t, J = 7.3Hz), 7.19- 7.25(1H, m), 7.35(1H, t, J = 7.8Hz), 7.52C2H, s), 7.53-7.59(2H, m), 7.72(1H, s), 7.76(1H, d, J = 7.8 Hz), 7.96 (1 H d, J = 8.3 Hz), 8.19 (1 H, t, J = 6.3 Hz), 8.27 (1 H, s), 8.62 (1H, d, J = 16.1 Hz). 1- 537 'H-NMR (GDCi3) δ 1.07(3H, t J = 7.3Hz), 1.8〇-1.86(2H, m), 3.12 (2H t J = 7.3Hz), 7.20-7.23(1H, m), 7.38 (1H, t J = 7.3HzX 7.54-7.58(2H( m), 7.79(1H, d, J = 8.3Hz), 7.90(1H, dt J = 7.8Hz), 7.98 (1H, s), 8.16(2H s), 8.18-B.20(1H, mX 8.38(1H, s)5 8.6(1H5 d). 1-538 'H-NMR (CDCi3) δ 1.11(3H, t, J = 7.3HzX 1.72-1.91 (2H, m), 2.64-2.86(2H, m), 7.20-7.23(1 H, m), 7.35(1 H, t, J = 7.3Hz), 7.53-7.57 (2H, mX 7.79(1H, d, ϋ = 7.5Hz), 7.85(2H, s), 7.95(1H, d, J = 7.8Hz)T 8.05(1H, s), 8.20(1Ht t J = 7.3 Hz), 8.33 (1H, s), 8.64 (1H, d, J = 16.0 Hz). 126 200836629, Table 5 (18)

— 北合编号-- Physical properties 値i 1-539 1 H-NMR (CDCl3) δ 7.19(1H, d, J = 8.3Hz), 7.34(1H, t, J = 8.3Hz), .41-7.59( 9H, m), 7.65(1 HT s), 7.74(1 H, d, J = 7.3HzX 7.96(1 H, d, =7.3Hz), 8.18(1H, dt, J = 8.3Hz), 8.60(tH s), 8.62(1H, s). \ 1-540 c H-NMRCGDCIs) 5 ?.39-7.41(4H, m), 7.42-7,59(7H, mX 7.67(1H, s), 7.72( 1H, if J = 7.3Hz), 7.8B-7.90(2H, m), 7.98(1 H, d, J = 8.3Hz), L04(1H, s), 8.22(1 H, s). 1-541 (H-NMR (CDCl3) 5 4.18C2H, s), 7.44 (2H, d, J = 7.8 Hz), 7.50-7.61 8H, m), 7.74 (1H, d, J = 7.8 Hz), 7.78 (1H, s), 7.88-7.94(3H, m), 5.03(1 H, s), 8.27(1 H, s). 1-542 H-NMR (CDC!3) d 4.18(2H, s), 7.19-7.25 (1H, mX 7.35(1H, t, J = 7.3Hz), 7.44(2H, d, J = 7.5Hz), 7.52C2H, s), 7.54-?.5B(2H, m), 7.60 ;2H, d , J = 7.8Hz), 7.75-7.77C2H, m), 7.92(1H, d, J = 6.BHz), 8.19 :1H, t J = 7.8Hz), 8.30(1H, s), 8.65(1H s 1-543 Ή-NMR (CDC[3) d 4.18(2H, s), 7.41-7.46(3H, m), 7.51 (2H, s), 7.55(1 H, t, ϋ = 7.8Hz), ?.60(2H, d, ϋ = 7.8Hz), 7.72(1 H, s), 7.77 (1H, d, J = 7.8Hz), 7.9K1H, d, J = 7.8Hz), 8 .2K1H, d, J = 2.0Hz), 8.24(1H, d, J = 8.3Hz), 8.42(1H, s), 8.54(1H s). 1-544 1 H-NMR (CDGi3) δ 4.13(2H } s), 7.46-7.54(5K m), 7.80(2H, d, J = 8,3Hz), 7.790H,d,J = 8.3Hz), 8.22—8.26(4H, m), 8·32 (2Η, d, J = 9.3Hz)5 8.95C1H, s), l0.18(1Ht s). 1-545 Ή-NMR (CDCI3) δ 4.16(2^ s), 7.13-7.20(2H, m) , 7.40-7.46 (4H, m), 7.52 (1H, t, J = Ε.3Ηζ), 7.60(2H, d, J = 8.3Hz), 7.71(1H, d, J = 7.3Hz), 7.82(1H , s), 7.86-7.93(2H, m)( 7.98(1H, d, J = 7.8Hz)f 8.21 (2H, d, J = 9.3Hz). 1-546 'H-NMR (CDCi3) δ 3.48( 2Hf qf J = 9.8Hz), 7.49-7.6〇(4H, m), 7.69 (2H, s), 7.73(1H, d, J = 7.8Hz), 7.87-7.90(3H, m), 7.95(1H} d, J = 7.8 Hz), 8.14C1H, s), 8.27(1H, s). 1-547 Ή-NMR (CDCi3) δ 3.49 (2K, q, J = 9.8 Hz), 7.20-7.25 (1 H, m), 7.35 (1H, t J = 7.8Hz)T 7.52-7.58(2H, m), 7.74(2H, s), 7.76(tH, d, J = 7.8Hz), T.BSdH, s)t ? .92(1H, d, J = 7.8Hz), 8.19(1H, t, J = 7.8Hz), 8.31 (1H, s), 8.64(1 H, d, J = 15.6Hz). 1-548 Ή- NMR (CDCI3) d 3.49 (2H, q, J = 9.8 Hz), 7.42-7.45 (1 H, m), 7.54 (1H, t J = 7.3 Hz), 7.73 ( 2H, s), 7.77-7.79 (2H, m), 7.92 (1H, d, J = 7.8 Hz), 8.21-8.23 (1H, m), 8.26 (1H, s), 8.43 (1H, s), 8.53 -8.55(1 H, m). 1-549 lH-NMR (CDCI3) δ 3.54 (ZH, q, J = 9.3 Hz) t 7.52 (1H, t J = 7.8 Hz), 7.73 (2H, s), 7.82 (1 H, d, J = 7.8 Hz), 8.23-8.27 (4H, m), 8.32 (2H, d, J = 9.3 Hz), 0.33C1H, s), 10.29(tH, s). 1-550 1 H-NMR (GDC13, ppm) δ 3.57 (3Hf s), 7.22-7.33 (6Ht m), 7.43 (1H, t ^=7.8 Hz), 7.67 (1H, s), 7J2-7.78 (2H, m), 8.30 (2H, s). 1-551 'H-NMR (GDCI3i ppm) δ 3.56 (3H, s), 7.21-7.34 (6H, m), 7.41 (1H, t J=7.8 Hz), 7.46 (1H, Brs) 7.60 (1H, s), 7.69 (1H, d, J=1.5 Hz), 7.70 (2H, s). 1-552 Ή-NMR (CDGI3l ppm) δ 3.99 (2H, brs), 6.66 (2H , s), 6.95-7.02 (4H m), 7.72 (1H, d, J=7.3 Hz), 7.93-7.96 (3H, m), 8.08 (1H, d, J=8.3 Hz), 8.25 (1H, s ), 8.85 (1H, s). 1-553 Ή-NMR (DMSO-de) δ 3.88(3H, s), 7.48~7.57(4H, m)t 7.71(2H, d, J = B.3Hz), 7.82(1 H, d, J = 7.8Hz), 8.02(2H dt J = 8.3Hz), B,10 (2Ht d, d = 8.3HzX 8.17(1H, d, J = 8.3Hz), B.4K1H, s), 10.06(1H, s), 10.9(1 H, si 127 200836629 Table 5 (1 fishing

- Adding the number - - - _ j 1-554 c (H-NMR (DMS 〇-d6) δ 2.09 (3Η, s), 7.50-7.63 (4H, m), 7.75 (1H, l, J=7.8 Hz), 7.79 (2H, s), 7.99-8.06 (3H, m), 8.35 (1H, s), 10.2 1K s), 10.3 (1H, si 10.5 (1H, s). I 1-555 ( ( H -NMR (.CDGI3) δ .7.40 (2Η, t J = 7.3Hz), 7·47-7.52 (5Η, m), 7.57 1H, t J = 7.3Hz), 7·64(2Η, s), 7.74 (1H,d,J = 8.3Hz), 7.87-7.97 6H, m), 8.25(1 H, d, J = 8.3Hz), 8.86(^, brs). 1 1-556 H-NMR (CDGi3, ppm ) d 3.01 (3H, d, J=4.8 Hz), 3.56 (3H. s), 6.27 1H, d, J=4.8 HzX 7.19-7.33 (6H, m), 7.38 (1H, t, J=7.8 Hz) , 7.58 ΊΗ, br), 7.65 (1H, s), 7.72 (1H, d, J=7.8 Hz), 7.94 (2H, s). 1-558 H-NMR (DMS〇-d6) δ 3.80 (3H, s), 7.40-7.43(1 H, m), 7.50(1 H, t J = 7.8Hz), 7.76(1H, s), 7.81(1H, d, J = 7.8Hz), 7.94(1K d, J = 7.8Hz), 8.1K1H, dt J = 8.3, 2.0Hz), 8.33(1 H, t J = 2.0Hz), 8.51 :1H, dd, J = 8.3, 2.0Hz), 10.48(1H, s), 10.78(1H, s). 1-559 H-NMR (DMS〇-d6) δ 3.80(3H, s), 7.2K1H, dd, J = 8.3, 10.2Hz), 7.30(1H, dd, J = 6.8, 7.8Hz), 7.51-7.55(2H, m), 7.76(1H, s), 7 .81 (1H, ddT ϋ = 1.5, 7.8HzX 7.93(1H, d, J = 1.5Hz), 8.12(1Ht d, J = 8.3Hz), 8.33(1H s), 9.62(1H, d J = 7.8Hz ), 10.78(1H, s). 1-560 lH-NiviRiCDCI3) δ t.68(SHf s), 7.48-7.54(3H, m), 7.58(1 H, d, J = 7.8Hz), 7.68(1) Ht d, J = 7.BHz), 7.78(1H, s), 7.86-7.92(3H, m), 7.97C1H, s), 8.1K1H, s), 8.25(1H, s). 1-562 'H -NMR (GDCi3, ppm) δ 3.44 (3H, s), 7.23-7.30 (5H, m), 7.41-7.45 (2H, m)f 7.71 (1H, brs)f 7.77 (1H, d, J=6.3 Hz ), 7.80 (1H, s), 8.02 (2H s), 8.22 (1H, s), 10.4 (1H, s). 1-563 1 H-NMR (CDCI3i ppm) δ 3.57 (3H, s), 7.21- 7.44 (8H, m), 7.61 (1H, s), 7.72 (1H, d, J=7.8 Hz), 8.01 (2H, s), 8.13 (1H, s), 8.58 (IK s). 1-564 1 H-NMR (CDCI3, ppm) &lt;5 3.57 (3H, s), 7.21-7.30 (7H, m), 7.34 (1H, dt, J = 7.3 Hz, J = 1.5 Hz), 7.41 (1H, t J =7.3 Hz), 7.87 (1H, s), 7.96 (1H dt, J=t5 Hz, J=8.3 Hz), 8.17 (1H, d, J=1.5 Hz), 8.35 (1H s), 8.65 (1H d , J=7.8 Hz) 1-565 lH-NMR (CDCI3, ppm) δ 7.53-7.62 (4H, m), 7.81 (1H, d, J=7.8 Hz), 8.00-8.02 (2H, m), 8.07 ( 1H, d, J=7.3 Hz), 8.40 (1H, s), 8.5? (2H, s), 9.9 0 (1H, s), 10.49 (1H, s), 1Q.51 (1H, s). 1-566 'H-NMR (GDCi3) δ 2.48(3H, s), 7.05(1 H s), 7.23( 1 Ht s), 7.50-7.62 (4H, m), 7.69 (1 H, d, J = 7.8 Hz), 7.84 (1 H, dd, J = 2.0, 7.8 Hz), 7.B9 (2H, d, Vl = 6·8Ηζ), s), 8.18(1H, d, J = 6·8Ηζ1 8·39(1Η, td = 1.9Hz), 8.89(1 H, s). 1-567 1 H-NMR (CDCI3 δ 2.33(3H, s), 3.56(3H, s), 7.03(1 H, s), 7.22-7.38 (6H, m), 7.45C1H, t J = 7.8Hz), 7.58(1H, s), 7.62(1H, s), 7.67C1H, d, J = 7.8Ης), 8,63(1 H, s). 1-568 ! H-NMR (CDC!3) δ 2.37(3H, s)t 3.21 ( 3H, s), 3.56(3H, s\ 7.20-7.29 (4H, m), 7.33-7.4K4H, m), 7.52(1H, s), 7.69(1H, d, ϋ = 7.8Hz), 7.72 (in s), a3〇oa s)_ 1-569 1 H-NMR (GDCI3) δ 2.38(3H, s)T 3.56(3H, s), 7.19-7.33(6H, m), 7.38-7.40(2H, m ), 7.42 (1H, s), 7.57 (1H, s), 7.61 (1H, s), 7.66 (1H, d, J = 7.8 Hz). 1-570 1 H-NMR (CDCIs) δ 2.03 (3H, s), 2.37(3H, s), 3.55(3H, s), 6.75 (1K s), 7,20-7.44(9H, m), ?.92(1H, s), 7.99(1K d, J = 7.8Hz). 128 200836629 Table 5 (2Q)

- ί 编号 number - 雠i 1-571 (H-NMR(DMS〇-d6) δ 2.30(3Η, sX 4.55(2HS d, J = Z.9Hz), 5.48 1H, broad), 7.5 7.60 (5H , m), 7.69-7.73 (2H, m), 7·98-8·00 (2Η, m), 8.06 (1 H, dd, J = 1.5, 8.3 Hz), 8.35 (1 H, t, ϋ = 1.5Hz), 9.93(1 H, s), i 0.48(lH, s). 1-572 . (H-NMR(CDCi3) δ 2.31 (3H, s), 3.36(3H, s), 3.53(3H, s), 4.44:2H, s), 7.17-7.40(8H, m), 7.49(1 H, s), 7.67-7.71(2H, m), 8.69 ΊΗ. si 1-573 H-NMR(DMS〇- D6) δ 1.96(3H, s), 3.84(2H5 broad), 7.53-7.63 C4H, m), 7.73(1 H, d, J = 7.8Hz), 7.89(1 H, s), 7.99-8.01 (2H , m), 8.07C1H, dd, J = 1.5, 7.8Hz), 8.19(1H, s), 8.33(1H, t, J = 2.0Hz), 10.43(1 H, s), 10.49(1 H, s 1-574 'H-NMRCCDCIs) δ 7.31(1H, d, J = 2.9Hz), 7.41(1H, d, J = Z.9Hz), 7.50-7.6K4H, m), 7.65(1H, broad- s), 7.74(1H, df J = 7.8Hz), 7.81 (1H, d5 J = 2.0Hz), 7.88-7.9K2H, m), 8.01-8.05(3H, m), 8.23(1H, broad - s) 1-575 'H-NMR(DMS〇-d6) δ 2.30(3H, s), 3.56(3H, s), 6.32(1 H, septet, J=5.9Hz), 6.85(1H, s), 7.19 -7.43(8H, m), 7.58(1Ht broad-s), 7.70 (1H, d, J = 7.8 Hz). 1-576 'H-NMRC DMSO-dg) δ 2.35 (3H, s), 7.05 (1 H, d, J = 2.4 Hz), 7.33 (1H, d, J = 2.4 Hz), 7.48-7.59 (4H?m), 7.67(1H, broad-s), 7.72(1H, d, ϋ = 7.8HzX 7.88-7.90C2H, m), 7.99-8.03(2H, m), 8.17(1H, broad-s) , 8.24(1 H, broad-s), 8.28(1 H, t, J = 1.0Hz). 1-577 lH-NMR(DMS〇-d6) δ 2.40(3H, s), 7.11(1H, d, ϋ = 2.5Hz), 7.20-7.25(1H, m)f 7.3〇-7.37(2H, m)5 7.53-7.5B(2H, m), 7.60(1H, s), 7.76 (1H, d, J = 7.8 Hz), 7.97-8.00(2H, m), 8.17-8.Z2(1H, m), B.29(2H, d, J = 8.8HzX 8.61, 8.65(1H, two broad-s). 1- 578 'H-NMRC DMSO-dg) δ 2.37(3H? s), 7.01 (2H, t, J = 8.3Hz), 7.09 (1H, d, J = 2.5Hz), 7.35(1H, d, J = 2.5Hz ), 7.42-7.46(1H, m)? 7.53 (1Ή, t, J = 8.3Hz), 7.65(1H, s), 7.76(1H, d, J = 7.8Hz), 7.92-8.00 (3H, m) , 8.23(1 H, s), 8.29(1 H, s). 1-579 lH-NMR(DMS〇-d6) δ 2.39(3H, s), 7.11(1 H, d, J = .2.4Hz) , 7.36 (1H, d, ϋ = 2.4Hz), 7.42-7.44(1H, m), 7.57(1H? t J = 7.8Hz), 7.63 (1H, s), 7.78C1H, d, J = 7.8Hz) , 7.95(1H, d, ϋ = 8.3Ης), 7.99(1Ht d, J = 2.0Hz), 8.21-8.25(2H, m), 8.29(1H, s ), 8.4K1H, s), 8.54-8.55 (1H, m). 1-580 lH-NMR (CDCi3) δ 3.560H, s), 7.13 (1 H, dd, J = 9.3, 2.4 Hz), 7.19- 7·23(2Η,m), ?JZ7-7.34(5H, m)t 7·39(1Η, d, J = 8·3Ηζ), 7.6K1H,t, J = 1.5Hz), 7.65(1 H, d, J = 8.3 Hz), 7.78 (1 H, d} J = 2.4 Hz) f 7.98 (1H, d, J = ZAHzl 8.13 (1H broad-s), 8.55 (1 H d, J = 9.3 Hz). 129 200836629 Table 5 (21)

ΊΙΜί number - one physical property 値5 1-581 1 H-NMR (CDCi3) δ 7.12~7.18(2H, m), 7.36-7.53(6H, m), 7.63(1Η, d, J = 2.0Hz), 7.68 (1H, d, J = 7.8Hz), 7.75(1K, s), 7.82(2H, d, J = 7.8Hz), 8.02-8.05(1 H, m), 8.21 (1H, s), 8.31 (1H , s), 8.53 (1 H, s). 1-582 H-NMR (CDCi3) δ 7.13-7.18(2Ht m), 7.31 (1H, dd, J = 4.9, ?.8Hz), 7.45-7.53 (3H , m), 7.7〇-7.73(2H, m), 7.84(1H, d, J = 1.5HzX 7.90 :1H, dd, J = 1.5f7.8Hz), 8.04(1H, dd J = 2.0, 7.8Hz) , 8.20(1H, s), 8.33(1 H, s), 8.42(1 H, dd, J = 2.0, 4.9Hz), 8.83(1 H, s). 1-583 lH-NMR(CDCi3) δ 7.49 -7.60(4H, m), 7.76(1 H, d? J = 7.8Hz), 7.83 (1H, d, J = 2·4Ηζ), 7.88-8.03C7H, m), 8.08(1H, s), 8.18 (1H, s), 8.29 (1H, t, J = 2.0Hz). 1-584 'H-NMRCDMSO-dg) $ 3.45(3H, s), 7.24-7.32(5H, m), 7.45-7.47 (2H m)T 7.77-7.80(2H, m), 7.92(1H, s), 8.22(2H, s), 10.49(1 H, broad). 1-585 ''H-NMRCGDClg) &lt;5 3.48(3H , broad-s), 6.80( 1H, broad), 7.01 (1H, broad), 7.1K1H, s), ?.14(1H, broad), 7.21-?.30(3H, broad-m), 7.78( 4H, broad), 8.38 (1H, 1-586; H-NMR (CDCi3) 3.52(3H, s), 7.09(1 H, dd, J = 4.9, 7.3Hz), 7.13 (1H, s), 7.34-7.36C2H, m), 7.53 (1 HT dd, J = 1.5, 7.8Hz) , 7.77^7.82 (4H, m), 8.21 (1H, dd, J = 2.0, 4.9Hz)? 8.41 (1H, s). 1-587 'H-NMRCDMSO-de) δ 7.53-7.64(4H, m) , 7.80(1 H, d, J = 7.8Hz), 7.92(1 H, s)f 7.99-8.02(2H, m), 8.07-8.09(1 H( m), 8.23(2H, s), 8.40 ( 1H, s), 10.50(1H, s), 10.57C1H s). 1-588 lH&quot;*NMR(DMS〇-d6) δ 7.33-7.40(2H, m), 7.54-7.63(2H, mX 7.68-7.72 (1 H, m), 7.80 (1 HT d, J = 7.8 Hz), 7.92 (1 H, s), 7.99 (1 H, dt J = 7.8 Hz), 8.23 (2H, s), 8.35 (1 H , s), 10.05 (1 H, broad), 10.66 (1H s). ^ 1-589 'H-NMRC DMSO-da) δ 7.56-7.60(2H, m), 7.82(1H} d, J = 7.8Hz) , 7.92-7.97(2H, m), 8.12(1 H, dd, J = 2.0, 7:8Hz), 8.23(2H, s), 8.33 (\H, d, J = 2.0Hz), 8.55(1H, Dd, J = 2.Q, 4.9 Hz), 10.55 (1H, broad), 10.90 (1 H, s). 1-590 ^H-NMRCDMSO-dg) δ 7.36-7.42 (2H, m), 7.57 (1H , t, J = 7.8Hz), 7.80(1 H, d, J = 7.8Hz), 7.92(1 H} s), 8.06-8.11(3H, m), B.23(2H, s), 8.38( 1H? s), 10.50 (1H, s), 10.56 (1H, s).

130 200836629 Table 5 (22)

- Compound No.:: Physical Properties 1-1 1-591 · H-NMR (CDCI3) δ 3.560Η, s), 7.12(1Hf s), 7.20~7.33(6H, m), ?.40(1H, t J = 7.8 Hz), 7.55(1H, s), 7.62(2H, s), 7.64(1H, d, J = l.OHz), 7.72(1H d, J = 7.8Hz). ϊ 1-592 H-iSiMR(DMS 〇-d6) 5 2.Z3(3H, s), 5.64(2H, s), 7.15(1H, s), 7.42;1Ht d, J = 1.5Hz), 7.50-7.63(4H, m), 7.68( 1H, s), 7.75(1H, d, J = 7.8Hz), 7.98-8.01 (2Hf m), 8.03-8.06(1 H, m), 8.35(1 H, s), 10.08 :1H, s), 10.46(1H, s). 1-593 H-NMR(GDCl3) d 2.30(3H, s), 5.33(2H, s), 6.94(1 H, s), 7.12 (1H, s), 7.15-7.2K1H , m), 7.28-7.33 (1H, mX 7.36 (1H, d, J = 2.0Hz), 7.44-7.54(2H, m), 7.72(1H, d, J = 7.8Hz), ?.86(1H, s), 7.90(1H, dd, J = 1.5, 7.8Hz), 8.1〇-8.15(lH, m), 8.25(1H, s)f 8.64(1H, d? J = 15.6Hz). 1-594 ' H~NiVlR(CDCi3) (5 2.24C3H, s), 5.39(2H, s), 6.94(1 H, s), 7.09 (IH, s), 7.28 (1 K dd, J = 4.9, 7.3 Hz), 7.33 (1 H, d, J = 1.5 Hz) t 7.42 (1K t J = 7.8 Hz), 7.67 (1H, d, J = 7.8 Hz), 7·83 (1Η, d J = 7.8 Ηζ), 7.92 (1H, s), 7.99(1H, dd, J = 2.0, 7.3Hz), δ.ίδ(1Η, s), 8.40(1H, dd, J = 2.0, 4.9 Hz), 8.85 (1 H, s). 1-595 'H-NMRiGDOis) δ 2.21 (3H, sX 3.5QOH, s), 5.39(2H, s), 6.94(1^., s), 7.10(1H? s), 7.13-7.19(2H, m), 7.21-7.27(4^m), 7.32(1H, t, J = 7.8Hz), 7.35(1H, d, J = 1.5Hz), 7.63 (1H, s), 7.70(1H, d, J = 7.8Hz), 7.76(1H, s). 1-596^-NMRCDMSO-da) δ 2.06(2H, quint, J = 7.3Hz)t 2.87(2HS t, ϋ = 7.3Hz), 3.12-3.14(2H, m), 7.52-7.63(5H, m), 7.75(1 H, d, J = 7.8Hz), 7.99-8.01 (2H? m), 8.07( 1 H, d, J = 7.8 Hz), 8.37 (1 H, s), 10.33 (1 H, s), 10.49C1K s). 1-597 lH-NMR (DMS〇-d6) δ 2.06 (2Ht quint, ϋ = 7.3Hz), 2.87(2H, % ύ = 7.3Hz), 3·13(2Η dd, J = 7.3, 12.2Hz), 7·33-7.40(2Η, m), 7-52-7.63 (3Ht m), 7.67-7.72(1 H, m), 7.75(1 H, d, J = 7.8Hz)? 7.97(1 H, d, ϋ = 7.8Hz), 8.33(1H, s), 10.35(1H, s), 10.66(1H, s). 1-5B8 i H-NMR(DMS〇-ci6) d 2.07(2H, quint J = 7.3Hz), 2.87(2H} = 7.3Hz), 3.15(2H, dd, J = 7.3, 1Z.2Hz), 7.45(1 HT s), 7.52-7.64(4H, m), 7.75(1H, d, J = B.3Hz), 7.98-δ.01(2Η, m), 8.06 (1H, dd, J = 1.5, 7.8 Hz), 8.37 (1H, t J = 1.5 Hz), 10.34 (1H, s), 10.49 (1H, s). 1-599 lH-NMR (DMS〇-d6) δ 2.07 (2H, quint, ϋ = 7.3 Hz), Z.87 (2H, t vi = 7.3 Hz), 3.15 (2H dd, J = 7.3, 12.2 Hz) , 7.33-7.40(2H, m), 7.45(1 H, s), 7.52-7.63(2H, mX 7.67-7.76(2HT m), 7.98(1 H, d, J = 7.8Hz), 8.33 (1K s ), 10.37(1H, s), 10.66(1H?s). 1-600 lH-NMR(CDCi3) ¢2.35 (3H, s), 7.12-7.16 (2H, m), 7.50-7.65 (5H, m) , 7.72 (1Hf dd, J = 1.5, 7.8Hz), 8.01 (2H, d, J = 8, 3Hz), 8.24 (1H, s), |10.2(1H, brs), 10.3 C1H, brs). 131 200836629 Table 5 (23)

: Compound No. - No. 1 1-601 1 H-NMR (DMSO-d6) δ 2.37 (3H, s), 7.29-8.01 (10H, m)f, 0.3 (1 H, s) T10.6 (1 H, s). 1 1-602 1 (H-NMR (DMSO-d6) ά 7.47-7.65 (5H, m), 7.75 (1 H, dd, J = 1.5, .BHz), 7.93 (1 H, d , J = 7.8Hz), 8.01-δ.04(2Η, m), 8.12(1 H, s), 8.17 1H, d, J = 8.8Hz), 10.17C1H s), 10.7K1K s). i 1- 603 ^ (H-NMR(CDCl3) d 3.22(3H, s), 3.42(3H, s), 7.17-7.23(1H, m), 7.29-^.35(2H, m), ?.49-7.57 ( 2H, m)t 7.64(1H, d, J = B.SHz), 7.B1-7.83 1H, m), 8.0〇-8.10(2H, m), 8.14-8.18(1H, m), 8.41(1H , s), 8.62 (1H, i, J = 15.1 Hz). ] 1-604 H-NMR (CDCt3) δ 1.09 (3Ht t, J = 7.3 Hz), 1.5K9H, s), 1.84-1.93 2H, m ), 4.38(2H, t, J = 6.8HzX 6.34(1 H, d, J = 8.3Hz), 6.95(1 H, d, J = 8.3HzX 7.09ClH, d, J = 7.8Hz), 7.18(1H , d, J = 8.3 Hz), 7.48-7.72 (7H, m), 7.79-7.81 (2H, m). 1-605 H-NMR (DMS 〇-d6) δ 7.51-7.63 (5H, m), 7.79 (1H, d, J = 7.8Hz), 7.83-7.86(2Ht m), 7.99-8.02(2H, m), 8.07(1 H, dd, J = 1.0, 8.3Hz), 8.38(1H, s), 10.48C1H, sX 10.63(1H, s). 1-96 ]H-NMR(DMS〇-d6) δ 7.54-7.59(2H, m), 7.80(1H, d, J = 7.8Hz), 7.S3(1HT dd, J = 1.0, 7.8Hz), 8.06-8.11(2H, m), 8.29-8.3K2H, m), 8.54(1 H, dd, J = 2.0, 4.9Hz ), 10.68(1 H, s), 10.88(1 H, s). 2-1 'H-NMR (DMS〇-d6) δ 6.15 (1H, dddd, J = 42.0, 11.6, 11.6, 5.6Hz), 7.47-7.59 (4H, m), 7.62 (2H, s), 7.78 (1H, d, J = 7.2Hz), 8.01 (2H, d, J = 7.2Hz)i 8.11 (1H, s), 8.38 (1H , s), 10.35 (1H, sX 10.40 (1H, s). 2-159 'H-NMR (DMSO~d6) δ 3.53 (3H, s), 5.80 (1H, brdd, J = 42.4, 5.6 Hz), 7.21-7.49 (7H, m), 7.55 (2H, s), 7.84 (2H, brs), 10.18 (1H s)· 2-160 'H-NMR (CDCi3) δ 3.53 (3H, brs), 5.02 (1H , dddd, J = 44.0, 10.8, 10.8, 5.2Hz), 6.83 (1H, brs)t 7.07 (1H, brs), 7.16-7.38 (5H, m), 7.52 (2H s), 7.61 (1Ht brs), 7.73 (1H, brs). 2-163 'H-NMR (GDCIg) δ 3.57 (3H, s), 5.02 (ΊΗ, brdd, J = 44.0, 5.6 Hz), 7.11-7.14 (1H, m), 7.39 ( 2H, brs), 7.49-7.59 (4Hf m), 7.73 (2H, brs), 8.26 (1H, brs). 2-166 iH-NMR (0DG13) δ 3.31 (3H, s), 4.97 (1Ht dddd, J =440, 112, 11.2, 5.2 Hz), 7.15-7.18 (2H, m), 7.40 (2H, s), 7.45-7.57 (3H, m)T 7.70 (1H, sX 7.76 (1H, ddd, J = 7.2 , 2. 0, 2.0 Hz), 7.82-7.92 (3H, m). 2-167 ^-NMR (CDCI3) δ 3.33 (3Ht s), 4.96 (1H, dddd, J = 44.0, 11.2, 11.2, 6.0Hz), 7.18 -7.21 (3H, m), 7.31-7.33 (1H, m), 7.40 (2H, s), 7.52-7.56 (1H, m), 7.71 (1H, brs), 7.74-7.76 (1H, m), 8 ,11-8.16 (1H, m), 8.40 (1H, brs). 2-170 lH-NMR (CDCI3) δ 3.31 (3H, s), 4.96 (1H, dddd, J = 44.0, 11.2, 11.2, 6.0Hz ), 7.21-7.28 (2H, m), 7.38-7.41 (3H, m), 7.69 (2H, brs)T 8.14 (1H dd, J = 8.0, 2.0Hz), 8.26 (1H, s), 8.52 (1H , t J = 2OHz). 2-173 'H-NMRCGDCls) δ 3.19 (3H, s), 4.97 (1H, dddd, J = 43.9, 10.7, 10:7, 5.7Hz), 7.16-7.20 (2H, m ), 7.39 (2H, s), 7.47-7.51 ClHt m), 7.67 (1K s), 7.72-7.75 (2H, m), 7.85 (1H, ddt J = 7.8, 1,5Hz), 8.49 (1H s) 2-174 •H-NMR (CDCI3) 6 3.30 (3H, s), 3.35 (3Hf s), 5.00 (1H, brdd, J = 44.0, 5.2Hz), 6.81 (1H, d, J = 7.2Hz) , 6.97 (1H, t, J = 8.0Hz)t 7.09-7.24 (6H, m), 7.36-7.39 (3H, m). 132 200836629 Table 5 (2磡

A compound number. 値I 2-175 , H-UMR (CDCI3) δ 3.30 (3Η, s), 3.34 (3H, s), 5.00 (1H, dddd, J = 44.0, 10.8, 10.8, 5.2Hz), 6.73-7.00 (4H, m), 7.15-7.26 (3H, m), ?.34 (1H, s), 7.38 (2H s). . 2-178 H-NMR (CDCl3) 5 3.29 (3H, s) r 3.37 (3H, s), 5.00 (1H, dddd, J = 44.0, 10.8, 10.8, 5.2Hz), 7.02 (3H, brd, J = 4.8Hz), 7.22 (1H, brd, J = 4.8Hz), 7.33-7.40 (4H, m), 8.22 (1H, brs). 2-181 H-NMR (GDCI3) i 3.29 (3H, s), 3.37 (3H, s), 4.99 (1H, brdd, J = 43.9, 5.4Hz),·6.99-7,07 (2Hf m), 7.23-7.26 (1H m)f 7.37-7.41 (1H, m), 7.38 (2H, s), 8.18 (1H, dt ϋ =2.4Hz), 8.26 (1H, d, J = . 2.4Hz). 2-182 Ή-NMR (CDCl3) δ 3.30 (3H, s), 3.41 (3H, s), 5.00 (1H, brdd, J = 43.9, 17.9Hz) , 6.89-6.91 (1H, m)( 7.08 (1H, ΐ, ϋ = 7.8Hz)? 7.26-7.29 (1H, m), 7.43 (2H, s), 7.44 (1H, t, J =2.0Hz), 8.48 (2H, s), 9.02 (1H, s). . 2-183 'H-NMR (DlVlSO-de) 5 2.30 (3H, s), 6.47 (1H, brdd, J = 41.0, 5.9Hz), 7.34 (1H, d, J = 2.4 Hz), 7.50-7.63 (5H, m), 7.77 (1H, d, J = 7.8 Hz), 7.94-8.01 (2H, m), 8.06 (1Ht dd, J = 8.3, 1.5Hz), 8.37 t J = 1.5 Hz), 1G.14 (IK, s), 10.4B (1H, s). 2-184 'H-NMR (GDCi3) δ 3.55 (3H, s), 5.43 (1H, brdd, J = 43.2, 5.6 Hz), 7.18-7.37 (6H, m), 7.54-7.55 (2H, m), 7.78-7.82 (3H, m), 9.91 (1H, s)., 2-185 Ή-NMR (DMS〇 -d6: CDCi3=1:1) δ 5.51 (1Ht brdd, J = 43.0, 5.4Hz), 7.44-7.57 (5H, m), 7.76 (1K d, J = 7.8Hz) t 7.80 (1H, d, J =2.4HzX 8.01-8.03 (2H, mX 8.20 (1H, d, J = 8.3Hz), 8.30 (1H, s)t 9.97 (1H, s), 10.15 (1H, s). 2-186 Ή-NMR ( CDC!3) δ 5.06 (1H, brdd, J = 44.0, 5.9Hz), 7.44 (1H, dd, J = 7.3, 4.9Hz), 7.55-7.59 (2H, m), 7.74-7.80 (3H, m) , 7.94 (1H, d, J = 7.8 Hz), 8.22-8.24 (2H, m), 8.40 (1H, s), 8.54-8.57 (1H, m). 2-187 lH-NMR(CDGl3) 53.54 (3H , s), 5.47 (1H, brddd, J = 5.9, 11.7, 42.9 Hz), 7.19-7.30 (4H, m), 7.31-7.36 (3Hf m), 7.82-7.84 (4H, m), 10.15 (1Hs) 2-188 'H-NMRCCDGls) (53.56 (3H, s), 5.01 (1H, brddd, J = 5.4, 11.Z, 49.3 Hz) T 7.13 (1H, dd, J = 4.9, 7.3 Hz), 7.41 (2H, s), 7.58 (1H, m), 7.72 (2H, (1H, d, J = 2.5Hz)t 7.86 (ΊΗ, d, J =2.5Hz), 8.25 (1H d, J =2.9Hz) , B.34 (1H, s).

133 200836629 Table 5(25) - Noisy number - Physical properties T 2-189 ( Γ ( H-NMR (CDCI3 > § 2.29 (6H, s), 4.95 (1H, brd, ϋ = 44.0Hz), 6.86 1H, d, J = 6.3HzX 6.96 (1H, s), 7.44-7.53 (3H, m), 7.57-7.61 (1K n), 7.63 (1H, brs), 7.71 (1H, d, J = 8.3Hz) , 7.86-7.90 (2H, m), 8.06 1H, dd, J = 8.3, 1.5Hz), 8.12 (1H, brs), 8.32 (1H, t, J = 1.5Hz) * I « 2-190 H-NMR CCDCI3) δ 2.20 (6H, s), 3.55 (3H, s), 5.00 (1H, brdd, J = 43.9, 5.9Hz), 6.95 (2H, s), 7.10 (1H, dd, J = 7.8, 4.9Hz ), 7.35 2H, brd, J = 4.4 Hz) f 7.44 (1H, s), 7.55 (1H, dd, J = 7.8, 1.5 Hz), ?.68 (1H, brd, J = 3.4 Hz), 7.73 ( 1H, s)t 8.23 (1H, dd, J = 4.9, LOHz). • 2-192 H-NMR (CDCi3) δ 2.31 (6H, s), 5.00 (1H, brddt J = 43.9, 5.9Hz)f 6.99 (2H, s), 7.35 (1H, t, ϋ = 8.3Hz), 7.47-7.63 (3H, m), 7.71 (1H, d, J = 11.2Hz), 7.82 (1H, t, J =2.0Ηζ) , 7.92 (2H, d, J = 7.3 Hz) t 8.08-8.14 (1K m), 8.58-8.63 (1H, m). 2-1.93 Ή-NMR (CDCi3) δ 2.32 (6H, s), 4.98-5.02 (1Ht m), 7Ό0 (2H, brs), 7.23-7.24 (1Ht m), 7.34-7.39 (2H, m), 7.56-7.60 (1H, m), 7.74 (1H, d, J =11.7HzX 7.85 (1H, ddd, J = 9.3, 1.5, 1.5Hz), 8.22 (1H, ddd, J = 7.8, 7.8, 2.0Hz), 8.67 (1H, ddd, J = 8.3, 8.3, 2.0Hz) , 8.80-8.90 (1K m). 2-194 Ή-NMR (CDCi3) δ Z31 (6H, s), 4.99 (1H, brdd, J = 44.4, 5.9Hz), 6.99 (2H, brs)f 7.38 (1H , t ϋ =8.3Hz), 7.4δ (1H, ddf J = 7.8, 4.9HzX 7.71 (1H, d? J = 11.2Ηζλ 7.88 (1H, ddd, J = 7.3, 7.3, 1.5Hz), 8.32 (1H, Dd, J = 7.8, 2.0 Hz), 8.57 (1H, dd, J = 4.9, 2.0 Hz), 8.61 (1H, ddd, J = 8.3, 8.3, 1.5 Hz), 8.74 (1H, brs). 2-195 'H-NMRC DMSO-ds) δ 2.30 (6H, s), 4.92-5.07 (1H, m), 6.98 (2H, s), 7.29-7.32 (1 H, m), 7.53-7.57 (3H, m), 7.60-7.64 (1 H, mX 7.80-7.84 (1H, m), 7.89-7.9K2H, m), 8.20 (!H, broad-s), 9.1〇-9.13(1H, m). 2-196 'H -NMRCDMSO-dB) δ 2.3K6H, s), 5.80-6.10(1H, m), 6.99(2H, s), 7.29-7.34(1 Hf m), 7.44-7.50(2H, m), 7.82-7.86 ( 1 H, m), 8.27 (1 H, dd, J = 7.3, 1.5 Hz), B.57 (1H ddT J = 4.9, 2.0 Hz), 8.75C1H, broad-s), 9.68 (tH, dd, J = 6.8, 2.0 Hz). 2-197 'H-NMR (DMSOd6) δ 6.59 (1H, brd, J = 41·5Ηζ), 7·53—7·63 (4H, m), 7.72-7.76 (1Ht m ), 7.90 (1H, d, J = 7.8 Hz), 8.01-8.05 (3H, m), 8.10-8.13 (1H, m), 8.38 (1Ht d, J = 8.8Hz), 8.45 (1Ht s), 9.08 (1H, t J =2.0HzX 10.50 (1H, s), 10.66 (tH, s). 2-198 'H-NMR (DMS〇-d6) δ 6.63 (1H, fardd, J = 41.0, 6.3 Hz), 7.34-7.40 (2H, m) , 7.58-7.62 (2H, m), 7.70-7.76 (2H, m), 7.90 (1Ht d, J = 7.8Hz), 8.01 (1Ht d, J =7.BHz), B.08 (1Ht s), 8.37-8.40 (2H, m), 9.09 (IK dd, J = 4.4, 1.5 Hz), 10.69 (2H, s). 2-199 Ή-NMR (DMSO-d6) δ 6.63 (1H, brdd, J = 41.0 , 5.9 Hz), 7.57-7.64 (2H, m), 7.75 (1H, dd, J = 8.8, 3.9 Hz), 7.93 (1H, d, J = 7.8 Hz), 7.98 (1H, dd, J = 7.8, 1.5Hz), B.OB-8.13 (2Hf m), B.38-8.40 (2H, m), 8.56 (1H, dd, J = 4.9, ZOHz), 9.08 (1H, dd, J = 3.9, 1.5Hz ), 10.71 (1H, s\ 10.91 (1H, s). 134 200836629 Table 5 (

Physical properties 値l 2-200 ί (W-NMR (DMS〇-d6) δ 3.46 (3H, s), 6.61 (1H, brdd, J = 41.0, LlHz)t 7.25-7.48 (7H, m), 7.73 (1H , brdd, J = 8.8, 3.9Hz), 7.83-^.88 (2H, m), 8.05 (1H, brs), 8.25 (1H, dd, J = 8.8, 1.5Hz), 9.06 1H, dd, J = 3.9, I.SHzl 10.58 (lH, s). 2-201 H-NMR (CDCl3) δ 6.07 (1H, dddd ( J = 53.2, 53.2, 2.9, 2.9 Hz), 7.43-7.58 (6H, m), 7.79 (1H, d, J = 7.8 Hz), 8.00-8.02 (2H, m), 8.18 (1H, d; J = 8.3 Hz), 8.34 (1H, s), 9.61 (1H. s), 9.95 (1H , s). 2-202 H-NMR (CDCi3) δ 5.93 (1H, dddd, ϋ = 53.2, 53.2, 2.9, 2.9 Hz), 7.18-7.36 (3H, m), 7.50-7.57 (3H, m), 7.77 (1H, d, J = 7.3 Hz), 7.82 (1H, sX 7.92-7.94 (1H, m), 8.17 (1H, brd, J = 1.5Hz), 8.31 (1H, s), 8.65 (1Hf brd, J=1.5Hz). 2-203 'H-NIVIR (CDCI3) $ 5.93 (1H, dddd, J = 53.2, 53.2, 2.9, 2.9Hz), 7.38 (1H, dd, J = 7.8, 4.9Hz), 7.49 -7.53 (3H, m), 7.76 (1H, brd, J = 7.8Hz), 7.89 (1H, s), 7.91 (1H, d, J = 1.5Hz), 8.14 (1H, dd, J =7.8, 2.0 Hz), 8.24 (1H s), 8-50 (1H, dcU = 4.9, ZOHz), 8.61 (1H, s). 2-204 Ή-NMR (CDCi3) δ 5.06-5.20 (2H, m), 7.25 ( 1H, d, J = 2.0 Hz), 7.46-7.57 (5H, m), 7.71 (1H, d, J = 7.8 Hz), 7.96 (2H, dd, J = 7.3, Ι.δΗζ), δ.1δ (1H, Dd, J = 7.8, 1.0 Hz), 8.28 (1H, t J = 2.0 Hz), 8.72 (1H, s), 9.51 (1H, s). 2-205 lHHSIMR(CDGi3) δ 5.12-5.25 (2HT m) , 7.21 (1H, ddd, J =11.7, 8.3, 1.0 Hz), 7.27 (1H, s), 7.32 (1H, ddd, J = 7.3, 7.3, 1.0 Hz), 7.48-7.55 (3H, m), 7.76 (1H, d, J = 7.8 Hz), 8.03 (1H, ddd, J = 7.8, 7.8, 2.0 Hz), 8.11 (1H, d, J = 8.3 Hz), 8.20 (1H, brs)t 9.07 (1H, s), 9.19 (1H, d, J = 1Q.7Hz). 2-206 'H-NMR (GDGI3) δ 4.97-5.12 (2H, m)T 7.40 (1H, dd, J = 7.8, 4.9Hz), 7·50-7.54 (2H, m), 7:67-7.70 (2H, m), 7.91 (1HT dd, J = 8.3, 1.5 Hz) t 8.15-8.20 (2H, m), 8.50-8.52 (2H, m). 2-207 'H-NMR (CDCi3: DMS0-d6=1:1) δ 5.51-5.67 (3H, m), 7.24 (2H, s)f 7.42-7.57 (3H, m), 7.66-7.69 (2Hf m), 8.00-8.02 (2H, m), 8.08 (1H, dd, J = 8.3, 1.5Hz), 8.36 (1H, s), 8.61 (1H, brd, J = 11.2Hz), 10.19 ( 1H brs). 2-208 1 H-NMR (CDGi3: DMS〇-d6=1:1) δ 5.99-6.25 (3H, m), 7.23-7.33 (4H, m), 7.46 (1H, t, J = 7.8Hz), 7.54-7.56 (1H, m), 7.68-7.72 (2H, m), 7.98-8.00 (1H, m), 8.29 (1H, s), 10.00 (1H, s), 10.46 (1H, s). 2-209 'H-NMR (CD€!3: DMSO-d5= 1:1) δ 6.00-6·25 (3H, m), 7·29 (2H, s), 7.45-7.52 (2Ht m), 7.72 (IH, d, ϋ =?.8Ης), 7.96-8.02 ( 2H, m), 8.24 (1H, d, J = 2.0Hz), 8.50 (1H} dd, J = 4.9, 2.0Hz), 10.03 (1H, s), 10.75 (1H, s). 135 200836629 Table 5 { 27) - ... - ...Chemical number 値1 2-210 ( ( 4-NMR (CDCb) d 5.15-5.31 (1H, m), 7.41-7.57 (4H, m)5 7.79 1H, d, 7.92 (2H , s), 8.0U.04 (2H, brd, J 2.7.3Hz), 8·18 1H, d, J =8.3Hz), 8.35 (1HT sX 9.85 (1H, s), 10.04 (1H, s). :\ 2-211 1 C H-NMR (CDCi3) ά 4.89-4.97 (1H, m), 7.1-8-7.26 (1H, m), 7.32-.3β (1H, m), 7.50-7.57 (2H? m), 7.76 (1H, d, J = 7.8 Hz), 7.89 (IH, i, J = 1.5 HzX 7.91 (2H, s), 8.02 (1H, s), 8.16 (1H, ddd, J = 7.8, 7.8 , LOHz), 8.32 (tH, t J =1-5Hz), 8.65 (1H, brd, J = 16.1 Hz). 1 2-212 ^ i H-NMR (CDCI3) δ 4.96 (1H, brd, J = 44.0 Hz), 7.37 (1H., dd, J = A 4.9Hz), 7·52 (1H, brd, J 7.8Hz), 7.75 (1H, d, J 2·7Ηζ), 7·89 1H, d , J = 8.3Ης), 7.90 (2 H, s), δ.02 (1H, s), 8.12 (1H, dd, J = 7.8, LOHz), 8·25 (1H, s), 8. (1H, dd, J = 4.9, 2.0H2 :), 8·64 (1H, s). 2-213 H-NMR (CDCi3: DMSO-de (5:1)) δ 5.7δ (1H, brd, J = 44.0 Hz), 7.46-7.59 (5H, m), 7.79 (1H, t? J = 2.0Hz), 7.90 (1H, t, J = 2.0Hz), S-00 (1H, d, J = K5Hz), 8.03 (1H, s), 8.12 (1H , dd, J 7.8, 1.5 Hz), δ.39 (1H, t J =2.0 Hz), 10.29 (1H, s)T 10.32 (1H, s). Xin• 2-214 H-NMR (CDCb) &lt ;5 5.30-5.95 (1H, m), 7.19-7.24 (tH, m), 7.32-7.36 m), 7.51-7-59 (2H, m), 7J6 (2H, d, J = 2OHz), 7.88 UH , d, J = 2.0Hz), 7.90-7.92 (2H, m), 8.18 (1H, ddd, J =7.3⁄4 7.8, 2.0Hz), 8.34 t J =2.〇Ηζλ 8.64 (1H, d, J =16.1 Hz). 2-215 1 H-NMR (CDCI3) δ 5.80-5.10 (1H, m)T 7.40 (t H, dd, J = 7.8, 4.9 Hz), 7.53 (1H, t, J = 7.8 Hz ), 7.75-7.78 (2H, m), 7.87 (1H? d, J = 2.0Hz), 7.88-7.91 (1H, m), 7.97 (1H, s), 8.16 (1H, dd, J = 7.8, 2.0 Hz)} 8.26 (1H, d, J = 2.0Hz), 8.51 (IH, dd, J = 4.4, 2.0Hz), 8.56 (1H, s). 2-216 !H-NMR (CDCI3) δ 3.55 (3HT s), 4.81-4.97 (1H, m), 7.19-7.33 (6H, m), 7.39 (1H? t, J = 7.8H zX 7.50 (1H, s), 7.58-7.61 (1H, m), 7·70-7.74 (1H, m)T 7.74 (1H, d, J II L5H£), 7.85 (1H, d, J =1.5Hz 2-217 'H-NMR (CDCi3) δ 3.53 (3H, brsX 4.74-4.98 (2HT m)T 6.84 (1H, brs), 7.08 (1H, brs), 7.17 (tH, dd, J =10r7T 8.3 Hz), 7.39-7.47 (3H, m), 7.55-7.60 (2H, m), 7.74 (1H, d, J = 2.0Hz), 7.86 (1H, d, J = 2.0Hz). 2-218 lH- NMR (CDCb) occupies 3.57 (3H, s), 4-91 (1H, brd, J 2 43.9 Hz), 7.13 (tH, dd, J - 7.8, 4.9 Hz), 7.39 (2H, d, J = 4.4 HzX) 7.58 (2H, brs), 7.71-7.75 (3H, m), 7.88 (1H, brs), B.25 (1H, d, J = 3.4Hz). 2-219 'H-NMR (CDCI3) 6 220 ( 6H, s)T 3.55 (3H, s)T 5.93 (1H, ddd, J = 54.2, 2.9, 2.9HzX 6.96 (2HT s), 7.10 (1H, dd, J = 7.3, 4.9Hz) T 7.35 (2H, d, J = 4.4 Hz), 7.46 (tHT s), 7.54 (1H, dd, J = 7.8, 2.0 Hz), 7.68 (1H, brd, J = 3.9 Hz), 7.73 (1H, s), 8.23 (1H , dd, J = 4.4, 1.5 Hz). 2-220 'H-NMR (CDCi3) 6 2.2B (6H, s), 5.00 (1H, brdd, J = 43.9, 5.4Ης), 6.87 (1H, d, J = 6.8 Hz), 6.97 (1H, s), 7.41 (1H, dd, J = 7.8T 4.9 Hz) T 7.52 (tH, t, J = 8.3 Hz), 7.58 (tH, brs), 7.72-7.74 ( 1H, m), 7.83-7.86 (1HT m X 8.17 (1H, dd, J - 7.8, 2.0 Hz), 8.27 (1H, brs), 8.52 (2H, brs). 2-8 ^-NMR (DMSO-d6) δ 6.18 (1H? brdd, J = 42.0 , 5.2Hz)T 7.23-7.32 (2H, m), 7Λ7-7.55 (2H, m), 7:62 (2H, s), 7J0 C1H, t J two 6.4Hz), 7.78 (1H, d, J = 6.8HzX 8.03 (1H, d, J = 7.6H2), 8.34 (tH, s), 10.38 (1H, s), 10.50 (1H, s). 4-1 'H-NIVIRCCDCis) 6 2.28(6H, s) , T.30-TM(5H, m), 7.34(2H, s), 7.51-7.64(4H, m)T 7.75-7J8(2H, m).. 4-2 lH-NMR(CDCI3) δ 2.29( 6H, s), 2.64(3H, s), 7.22-7.36(4H, ml 7.34C2H, s), 7.43-7.47(2H?m), 7.57-7.680H, m), 7.99(1 H, d, J = 7.3HzX 4-6 'H-NMRCCDCis) δ 2.29(6H, s), 7.32-7.39(6«, m), 7.58-7.66 (6H, m). 136 200836629 Table S(2S)

-fc compound number" physical property i 4 4 ( ( H-NMR(CDGl3) δ 2.31 (6Η, s), 7.35(2H, s)f 7.43-7.47(2H, m)5 7.49 1H, s) , 7.53(1H, s), 7.61-7.65(1H, m), 7J1-7.77(3H, m), 7.87-7.91 2H, m). 1 4-16 (H-NMRCCDCI3) δ 2.33(6H, sX 7 „36(2Ht s), 7.42-7.490H, mX 1J\ 1H, d, J = 6.8Hz), 7.BK1H, s), 7.89(1H, s). 1 4-24 H-NMR(CDCl3) δ 2.29(6H, s), 2.85(3H, s)f 3.35(3H, s), 7.34(2H, s), 7.49(1H, t, ϋ = 7.8Hz), 7.58(1H, dd, J = 1.0, 7.8 Hz), 7.8〇-7.83(2H, r〇, 7.96(1 H, s). 4-25 H-NMR(CDCI3) a 1.35(3R t, J = 7.3Hz), Z.32(6H, s ), 3.14(2H, q, J = 7.3Hz), 7.2B(1H, s), 7.35(2H, s), 7.42-7.48(2H, m), 7.66-7.71 :2H, m), 7.80(1 H, s). 4-26 H-NMR (CDCi3) δ 1.33 (3H, t( ϋ = ?.3Hz)f Z.27(6Ht s), 3.03(2H, q, J = 7.3Hz), 3.35( 3H, s), 7.33(2H, s), 7.44(1 H, t, ϋ = 7.8Hz), 7.57( 1H, d, J = 7.8Hz), 7.79(1H, d, J = 7.8Hz), 7.97 (1H, s), 8.05(tH, s). 4-27 lH-NMR(GDCl3) δ 2.27(6H, s), 3.73(2H, q, J = 8.8Hz), 7.33(2H, s), 7.39 -7.45(2H, m), 7.6B-7.7K1H, m)t 7.83-7.85(2H, m), 8.09(1H, s). 4-28 lH-NMR(CDGl3) δ Z.27(6H, s), 3.40(3H, s), 3.75(2H, q, J = 8.8Hz), 7.34(2H, s), 7.51 (1H, t, J = 7.8Hz)? 7.58( 1 H, d, J = 7.8 Hz), 7.86 (1 H, d, J = 7.8 Hz), 7. B0 (1H, s), 7.97 (1H, s). 4-29 'H-NIVIRCCDGis) δ 2.25 (6H, s), 5.87(1H, d, J = δ.δΗζ), 6.19(1H, d, J = 16.1Hz), 6.46(1H, dd, ϋ = 9.8,16.1Hz), 7.23-7.35(5H , m), 7.61 (IH, s), 7.75(1H, s), 7.94(1H, s). 4-30 lH-NMR(CDCl3) δ 2.28(6H, s), 3.25(3H, s), 6.03 (1 H, d, J = 9.8HzX 6.18(1HT d, J = 16.6Hz)? 6.42(1H, dd, J = 9.8,16.6Hz), 7.33(2H, s), 7.44(1H, t J = 7.8 Hz), 7.51 (1HT d, J = 7.8Hz), 7.80(1H, d, J = 7.8Hz), 7.9K1H, s), 7.94(1H, s). 4-31 lH-NlVlR(DiVIS〇-d6 δ 1.02(3H t, J = 7.3Hz), 1.80-1.90(2H, m), 2.35(6H, s), 3.05-3.09(2H, m), 7.32(2H, s), 7.42(1 H, t? J = 7.8 Hz), 7.50-7.53 (1H, m), 7.71 (1H, d, J = 7.8 Hz), 7.86 (1^d, ϋ = 2.0 Hz), 8.54 (1 H, s), 9.24 (1 H s). 4-32 'H-NMRCCDCIs) 6 1.01 (3H, t, vi = 7.8 Hz), 1.77-l.87 (2Hf m), 2.28 (6H, s), 2.97 (2H, t, J = 7.8 Hz), 3.35 (3H, s), 7.34 (2H, s), 7.45 (1H, t, J = 7.8 Hz) ( 7.57 (1 H, d, J = 7.8 Hz), 7. 80(1 H, d, J = 7.8Hz), 7.9? (2H, s). 4-33 'H-NMRiCDCIs) δ 1.37(6H, d, J = 6.8Hz)t 2.32(6H, s), 3.31 (1H, septet, J = 6.8Hz), 7.24(1H, s), 7.35(2H, s), 7.41-7.49(2H, m), 7.66 (1H, d, J = 7.3Hz), 7.7K1H, s ), 7.81 (ΊΗ, s). 4-34 'H-NlVlRCCDCis) δ 2.35(BH, s), 4.37(2H, s), 6.72(1 H, s), 121-1.31 (8Hf m\ 7.43-7.47 C2H, m), 7.62 (1 H, d, J = 2.0 Hz), 7.68 (1 H, d, J = 7.8 Hz). 5-1 'H NMR (CDOi3) dZ.35 (6Ht s), 5.89 ( 1Hf brs), 7.01 (1H, t, J = 7.3Hz), 7.14 (2H, dt J =7.3Hz), 7.28-7.40 (8H, m), 7.80 (1H, brs). 5-2 NMR(GDCI3) ί Z.28 (3H, s), 2.35 (6H, s), 5.58 (1H, brs), 7.00 (1H t, J = 7.3Hz), 7.09 (1H cU = 7.3Hz), 7.18 (1ΗΛ J = 7.3 Hz), 7.24-7.35 (7H, m), 7.53 (1H, brs). 137 200836629

One heavy compound number te値I 5-4 i 1: H NMR (CDCl3) (52.35 (6H, s), 5.98 (1H, brs), 6.64-6.69 (1H, m), 180-6.85 (2H, mX 7.20-7.24 (1H, m)T 7.31-7.43 (6H, m), 7.63 (1H, 3rs). 1 5-5 H-NMR (CDCI3) 52,34 (6H, s), 5.88 (1H, brs) , 7.00 (2Ht d, J = 8.8Hz), 7.36 (2H; s), 7.38-7.41 (6H, m), 7.59 (1H, brs). , • 5-8 H-NMR(GDGi3) δ 2.37 (6H , s), 6.85-6.89 (1H, m), 7.32 (1H, d, J = 8.8Hz), 7.37-7.46 (4H, m), 7.51-7.59 (2H, m), 7.71 (1H, d, J = 7.3 Hz), 7.87 (1H, brs), 8.23 (1H, dd, J = 8.8t1.5Hz), 9.54 (1H, brs). 5-9 H-NMR(GDCi3) § 2.36 (6H, s), 6.50 (1H, brs), 7.02 (ZHt d, ϋ = δ.7Ηζ), 7.38 (2H, s), 7.42 (1H, s), 7.46 (1H, d, J = 7.8Hz)t 7.53 ΠΗ, t, J = 7.8 Hz), 7.60 (1H, d, J = 7.8 Hz), 7.91 (1H, brs), 8.19 (2H, d, J = 8.7 Hz). 5-10 'H-NMRCCDCy (5Z.32 (6H) , s), 3.81 (2H, brs), 5.42 (1H, brs), 6.76-6.83 (2H, m), 6.87-6.89 (1H, m), 7.05-7.09 (1H, m), 7.12 (1H, d , J = 7.8 Hz)? 7.27-7.37 (6H, m). 5-11 'H-NMRCCDCls) δ Ζ33 (6H, s), 5.60 (1H, brs), 6.64 (2H, brs), 6.69 (2H d , J = 8.8Hz) i 7.00-7.02 (3H, m), 7.23-7.37 (6H, m). 5-12 ^-NMRiCDCig) 6'2.34 (6H, s), 6.04 (1H, brs), 7.20-7.52 (10H, m), 7.64 (1Ht Brs). 5-13 'H-NMRiCDCls) ^2.08 (3H, s), Z3Z (6H, s), 5.98 (1H, brs), 6.98 (1H, d, J =7.3Hz), 7.16-7.22 (2H , mX 7.29-7.40 (7H, m), 7.59 (1H, brs), 7.68 (1H, d J =7.3Hz). 5H4 'H-NIVIRCCDCIs) 52.13 (3H, s), 2.33 (6H, s), 5.87 (1H, brs), 7.06 (2H, d, J = 8.8 Hz), 7.19 (1H, brs), 7.30-7.41 (7H, m), 7.50 (1H, brs), 7.53 (1H, brs). 5- 15 ^ 'H-NMRCGDCis) δ 2.34(6H, s)t 5.74(1 H, broad-s), 6.83-6.95(2H, m), 7.15-7.18(1H, m), 7.18-7.39(6H, m ), 7.54(1H, broad-s). 5-21 'H-NMRCCDCIs) 52.36 (6H, s)5 6.73-6.77 (2H, m), 6.96 (1H, d, J =7.3Hz), 7.33-7.38 (3H,m), 143-149 (2H, m), 7.56-7.58 (2H,m), 8.12 (1H, s). 5-23 'H-NMRCCDGis) §2.31 (6H, s), 6.08 (2Ht brs), 7.35 (2H, s), 7.43-7.59 (2H, m), 7.70-7.82 (3H, m), 8.29 (1H, brs). 5-24 'H-NMRiCDCis) ^2.33 (6H, s), 5.93 (2H, brs), 7.36 (2H, s), 7.45-7.49 (2H, m), 7.63 (1H, s), 7.85 (1H, d, J = 7.3Hz), 7.92 (1H, s ), 8.04 (1H, s). 5-25 Ή -ΝΜΗίΟΜΒΟ^ρ) δ2.ΖΒ (6Ht s), 5.90 (2H, brs), 7.30-7.36 (2H, m), 7.43 (2H, s), 7.75 (1H, d, J = 7.8Hz), 8.04 ( 1H, brs), 8.85 (1H, brs), 9.80 (1H, brs), 11.2 (1H, brs). 5-26 ^H-NMRlDMSO-dg) d2.33 (6H, sX Z.83 (6H, s )t 7.10-7.21 (3H, m), 7.43 (?H. sCi. 9_96 f1H. si 138 200836629 Table 5 (3_二二-.二二二-.....-- ir number...- physical properties値· —— 5 - 27 'H-NMRCCDGla) δ 0.92(3Ht t, ϋ = 7.3Hz), 1.59-1.69(2H, m), 2.72 (2H, t ϋ = 7.8Hz), 3.03(6H, s), 6.93 (1 H, dd, J = 2.4, 8.3 Hz), 7.23 (1H, d, J = 8.3HzX 7.32-7.39C2H, m), ?.50(1Hf s), 7.55(1H, s), 7.95(1H , dv J = 1.5Hz). —— 5-28 lH-NMR(CDCl3) δ 1.23(6H, d, J = 6.8Hz), 3.04(6H, s), 3.25(1H, septet, J = 6.8Hz) , 6.93(1 H, dd, J = 2.0f?.8Hz), 7.23(1 H, t, J = 7.8Hz), 7.33-7.39(2H, m), 7.51(1H, s), 7.57(1H, s), 7.95 (1H, d, J = 2.0 Hz). 5-29 'H-NMRCGDCig) δ 3.05(6H, s), 3.07(3H, s), 6.97(1 H, dd, J = ZQ, 7.8 Hz), 7.25-7.27(1 H, m), 7.32-7.33(1 H, m), 7.39(1 H, t, J = 7.8Hz), 8.20(1 H, d, J = ZOHz), 8.26( 1 H d, J = 2.0Hz ), 8.89(1 H, s). 5-30 ]H-NMR (CDCi3) δ 3.04(6H, s), 6.95(1H, dt J = 7.8Hz), 7.21-7.23 (1K m), 7.33-7.39 C.sub.2, m. 1H, brdd, J = 8.8, 2.0 Hz), 7.28-7.36 (3H, m), 8.06 (2H, s), 10.34 (1H, s). 5~32 Ή NMR (CDCI3) δ 2.84 (6H, s) , 3.35 (3H, s), 6.63-6.65 (1H, m), 6.73 (1H, d, J = 3.9Hz), 6.75 (1H, s), 7.03 (1H, t, ϋ =8.3Hz), 8.09 ( 2K s). 5 - 33 Ή-ΝΜΗ(0Ρ0ί3) δ 1.57(3H, d, J = 6.8Hz), 2.28(6H, s), 2.74(3H, s), 5.18C1H, q, J = 6.8Hz) , 6.99(1H, dd, J = 2.4, 8.3Hz)t 7.15(1H/d, J = 7.3Hz), 7.22-7.35(8H, m), 7.4K1H, s), 7.55(1H, s). Table 5(31) Chemical number i Physical properties 値6-1 I 1HtIMMR(CDCI3) δ 2.36(6Ht s), 7.34(2HT s), 7.46-7.57C4H, m)t 7.76(1 H, d, J 7.3Hz) , 8.00 (2Ht d, J = 7.3Hz), 8.13 (1 H, cU two 7.3 Hz), 8·35 (1Η, s), 9-10 (1 H, broad-s), 9.88 (1 H, broad -s). 6-2 1H-NMR(CDG13) 6' 2.33(6H, s)T 7.35(2H, s), 7.39-7.46(1 HT m), 7.52(1 H, t, J 7.8Hz), 7.73-7.75 (2K m), 7.83 (1 K d, J = 8.3 Hz), 8.16 (1 K ddf J = 7.8 T2.0 Hz), 8.30 (1 H, broad-sX 8.52 (2H, ddf J = 4.9r2.0 Hz). 6-3 1H-NMR (CDC!3 δ 2.34(6H, si 3.55(3H, s), 7.13(1 HT broad-s), 7.19-7.42(9H, m)T 7.55(1 H, broad-s), 7.89 (1 H, d J = 6.8 Hz)·6-4 1H-NMR (CDCI3) δ 2.28(6HT s), 3.57(3HT sX 7.11-7.14(1 H, mX 7.30-7.37(4H, m), 7.57(1 H,d,J = 6.8 Hz) T 7-68-7.72 (3H, m), 8·24 (1 H, d J 3.4 Hz). Injury 6- 5 1H-NMR (CDCI3) δ 2.34 (3H, s) ¥ 3.55 (3H , s), 7.19-7.72 (12K m). 6-δ 1H-NMR (CDCi3) 2^8(3/2HT s), 2.37(3/2HT s\ 3.58(3H, s), 7.11-7.15(1 Hr m), 7.37-7.41 (3H, m)· 7.48-7.64 (3H, m), 7.82 (2Η, broad-s), 8.25 (1 H, broad-s). 6-7 1H-NMR( CDCI3) &lt;5 7.5〇-7.59(4H, m), 7.75(1 H, dd, J = 6.8r1.5Hz), 7.88-7.92(2H,m). 7·99-8-05(4K m) , 8.29 (1H, broad-s), 8.30 (1H乂J 2·5Ηζ)·6-8 1H_NMR(CDGI3) &lt;5 7Λ3—7-4S(1H,m),7·57(1Η,t J = 7·8Ηζι), 7.76-7.80(1!4, m), 7.93-8.03(3^m), 8.21-8.27(2H, m), 8.32(1 H, s), 8.40(1 H, broad- s), 8.56 (1 H, t J = 1.5 Hz:). 6-9 1H-NMR (CDGI 3) δ 7.49-7.59(5H, m), 7.73-7.75 (1 H, mX 7.88-7.92C3H, mX 8.12-8.13 (1 H, mX 8.20(1 H, broad-s)T 8.30(1 H, d , J = 7.4Hz), 8.36(1 H, broad-s). *6-10 1{-Ην1ΜΚ^ΟΟ!3)δΙ43-7.46(1Η,Γη),7·56(1ΗΛϋ = ;?·6ΗζΧ7· 75-7.80(1Η,Γη), 7.90(1 H,d,J=7.3·3Ηζ),8.12-8.15(1 H,m),8.21-8.24(1 H,m), 8.30(1 H,broad- s), 8.33 (1 H, broad~s), 8.46-8.48 (2H, m), 8.54-8.58 (1 H, m). 6_11 1H-NMR (CDCI3) 6' 3; 56T3.57 (3H, two s), 7.23-7.330H, m), 7.38-7.48(3H, m), 7.53-7.57(1 H, m), 7.67-7.72(2H, m)( 8.03-8.04(1 H, mX 8.10-8.11 (1H, mX 8.26(1 H, broad-s)· 6-12 1H-NMR(CDCI3) 6 3.58(3H, sX 7.14-7.16(1 H, mX 7.45(2K broad-s), 7.52-7.80(3H . ml 8.10(1 H. broad-si 9.21-8.30(3K m). 139 200836629 Compound No. 1-187 Physical Properties 値1H-NMR(CDC13) (5 3·54(3Η,s), 7 i g-7 】 2 (ffi, m), 7·27·7·30 ( 3H, m), 7·33-7·36 (1Η, m), 7·42 (1Η, t5 J =7·8Ηζ), 7.57 ( 13⁄4 s), 7·67_7·70 (1Η, m), 7.88 (13⁄4 s), 8.02 (13⁄4 d, J = 2·0Ηζ), 8·10 (1H, d, Bu 2·0Ηζ ). Specific examples of pests which can be controlled by the insecticidal composition of the present invention, for example, Endoclyta excrescens, Endoclyta sinensis, and Palpifer sexnotata (Lepidoptera moth, LEPIDOPTERA) Dasheen tree-borer), Acleris comariana (Avixophyes oranafasciata), Adoxophyes sp., Archips breviplicanus, Archips foscocupreanus, Archips xylosteanus Cleaved leaf moth, Apple leaf roller, Bactra forfurana, Cnephasia cinereipalpana, Cydia kurokoi (Nut fruit tortrix), Eucoenogenes aestuosa (Chestnut worm) Heartworm), Grapholita inopinata, Grapholita molesta, Homona magnanima, Hoshinoa adumbratana, Leguminivora glycinivorella, Matsumuraeses azukivora , Matsumuraeses Mcana (soybean worm), Mats Umuraeses phaseoli (Azuki pod worm), Olethreutes 11101: Hansui leaf moth, apple white leaf moth (8卩丨1〇11 (^ with 111 such as 3卩丨5), 8卩丨1〇11 (^ Ocellana (Eye_spotted bud moth), Eupocelilla ambiguella, Phalonidia mesotypa, Phtheochroides clandestine, Cydia pomonella, grape fruit worm Endopiza viteana, Bambarina sp. (Ethopean moth), Eumetajaponica, Eumetaminuscula, Nemapogon granellus, Tinea translucens, Bucculatrix pyrivorella Pear leaf miner, Peach leaf moth (1^〇11^11&amp; clerkella), Lyonediamnifoliella (Silver leaf miner), Caloptilia soyella (Cole moth), Caloptilia theivora, Calopyilia zachrysa (apple moth), 140 200836629

Cuphodes diospyrosella (persimmon, moth), Phyllonorycter ringoniella (gold, moth, apple leaf miner), Spulerrina astaurota (Pear moth), Phylocnistis citrella, Phyllocnistis toparcha (Acerola moth), Acrolepiopsis Sapporensis (Scallion moth), Acrolepiopsis suzukiella (P. sylvestris), Plutella xylostella, Argyresthia conjugella (Apple fruit moth), Paranthrene regalis (Grape clearwing moth), Synanthedon hector ( Small tree borer, Cherry tree borer, Stathmopodamasinissa, Brachmiatriannulella, Pectinophora gossypiella, Phthorimaea operculella, Carposina niponensis, Peach fruit Moth), Illiberis prnni (apple leaf black-winged moth), Latoia sinica (black-spotted moth), yellow-spotted moth (]\^01^11^£1^^306113), pear moth (7^1* 08(^(161^他¥丨(1(like &amp; also), sa 剌 (Parasa consocia), Scopelodes contracus (姬黑剌), 二化填(Chilo Suppressalis), Cnaphalocrosis medinalis, Conogethes punctiferalis, Diaphania indica, Ectomyelois pyrivorella, Ephestia elutella, Ephestia kuehniella Spotted moth), Etiella zinckenella, Euzophera batangensis, Glyphodes pyloalis, Hellulla midalis, Marasmia exigua (rice leaf roller) , Marnca testulalis, Notarcha derogata, Ostrinia fumacalis, brown-winged wild moth (〇3103血5〇&amp;卩111&amp; also), 〇313±^ Zaguliaevi (japanese butter bur borer), turf moth (Parapediasia teterrella), Pleuroptya mralis (Tujin wild moth, Bean webworm), Plodia interpuctella, Scirpophaga incertulas, Parnara guttata, Papilio helenus, Papilio machaon hippocrates, Swallowtail, Papilio xuthus, Colias erat e poliographus (Oriental clouded yellow), Pieris rapae cmcivora, Lampides boeticus, Angerona pranaria (Li 141 200836629

蠖), Ascotis selenaria, Biston robustum, Cystidia couaggaria, Dendrolimus spectabilis, Malacosoma neustria testacea, Odonestis Prnni japonensis (Apple dead leaf moth), Cephonodes hylas, Acosmeryx castanea, Clostera anachoreta, Clostera anastomosis, Phalera Flavescens), Phalerodonata manleyi, Stauropus fagi persimilis, Euproctis pseudoconspersa, Euproctis similis, Euproctis subflava, gypsy moth Lymantria dispar), Orgyia thyellina, Hyphantria cunea, Spilosoma 111^^11115 (Sanghu moth), Soybean stalk (Ins; 111; 110卩11^&amp;&amp; job 3{&amp;), Aedia leucomelas, Agrotis ipsilon, Agrotis segetum, Anomis flava, Anomis meso Gona), Autographa nigrisigna, Trichoplusia ni, Helicoverpa armigera, Helicoverpa assulta, Heliothis maritima, Fux bud worm , Maamestra brassicae, Naranga aenescens, Pseudaletia separata, Sesamia inferens, Spodoptera depravata, Spodoptera exigua, twill Spodoptera litura, Triaena intermedia, Viminia mmicis, Xestia o nigrum, spotted cutworm, etc.; Hemiptera (HEMIPTERA), Heteroptera (Heteroptera) Megacopta punctatissium (round pile elephant, Globular stink bug), Carpocoris purpureipennis (purple pile elephant), Dolycoris baccarum (beauty pile elephant), blue pile elephant (Eurydema pulchrum), Eurydema rngosum (vegetable pile image, Cabbage bug ), Eysarcoris guttiger, Eysarcoris lewisi, Lewis spined bug, Eysaxcoris parvus, white star statue Eysarcoris ventralis), Glaucias subpunctatus (f^青青象), Black-streaked red-grass (Graphosoma rubrolineatum), Halyomorpha mista (Smelly Pile, 142 200836629

Brown-marmorated stink bug), Lagynotomus elongatus (Rice ifiSk bug), Nezara antennata, Nezara viridula, Piezodoms hybneri, and small piles Plautia stali), Scotinophara lurida, Starioides iwasakii (Iwasaki pile), Acanthocoris sordidus, Anacanthocoris striicomis, and rice thorns (Cletus punctiger) ), Cletus trigonus, Molipteryx fiilginosa, Leptocorisa acuta, Leptocorisa chinensis, Corbett rice bug, Leptocorisa oratorius Taiwan's checkpoints, Riptortus clavatus, Aeschynteles maculatus, Liorhyssus hyalinus, Cavelerius saccharivorus, Macropes obnubilus Winged long pile elephant), Pachybrachius luridus (Gourd small flat long pile elephant), Paromius exiguus (black foot slender pile image), Togo hemiptems (Gourd small winged long pile elephant), red star Piles (Dysdercus cingulatus), Dysdercus poecilus, Galeatus spinifrons, Metasalispopuli, Stephanitis fasciicarina, Stephanitis nashi , Stephanitis pyrioides, Uhlerites debile, Uhlerites latius, Adelphocoris lineolatus, AlMfe plant bug, Adelphocoris triannulatus, Apolygus lucomm, Apolygus spinolai, Creontiades pallidifer, Cyrtopeltis ternmis (tobacco blind pile), Ectometopterus micantulus (large black-brown pile) Halticiellus insularis (black-brown blind elephant), Heterocordylus flavipes (apple black blind pile), Lygus disponsi (blind blind image), Lygus saundersi (spotted blind elephant), Orthotylus flavosparsus (beet blind pile), Stenodema calcaratum (Silk blind pile elephant), Stenotus binotatus (double blind pile elephant), Stenotus mbrovittatus (red striped blind elephant), Ta Ylorilygus pallidulus (light green blind pile), Trigonotylus coelestialium (red whisker), Ghoptopsaltria nigrofUscata (Homoptera) (oil 蝉, 143 200836629)

Large brown cicada), Aphxophora costalis (pre-yellow), Aphrophora flaVipes, Aphrophora vitis, Clovia punctata, Philaenus spumarius, Bothrogonia japonica ( Black-tailed scorpion), Cicadella viridis, Cofana spectra, Aguriahana quercus, Alnetoidia alneti, Apheliona fermginea, Arboridia apicalis Double-pointed Jifu dust), Edwardsiana flavescens, Edwardsiana rosae, Empoasca abietis, Empoasca onukii (Tea green leafhopper), Thaia submfa (rice magnolia) ), Zyginella citri, Honeysteles fascifrons, Nephotettix cincticeps, Nephotettix nigropictus (Neurotettix virescens), Orientus ishidai (Apple striated) Floating dust), electro-optical dust (Recilia dorsa Lis), Sorhoanus tritici, Speusotettix subfUsculus, Laodelphax striatellus, Nilaparvata lugens, Numata muiri, Pale sugarcane planthopper, Corn planthopper (Peregrinus maides), Perkinsiella saccharicida (Sweet cane planthopper), Sogatella fUrcifera, Sogatella panicicola, Anomoneura mori, Mulberry sucker, Calophya nigridorsalis Diaphora citri, Diaphorina citri, Mesohomotoma camphorae, Psylla abieti, psylla aM, Psylla jamatonica, Psylla mali Apple Woods, Psylla malivorella, Psyllapyrisuga, Pear sucker, Psylla tobirae, Tobera sucker, Trioza camphorae, Trioza quercicola Sharpwood), Aleurocanthus spinifcms, Aleurolobiis taonabae (Grape meal, Gr Ape whitefly), Bemisia tabaci, Dialeurodes citri, Trialeurodes vapomriomm, Silver leaf powder 61]^1&amp;&amp;rent 61^&amp;out) Grape 144 200836629

Roots vitifolii, Aphidounguis mali, Eriosoma ianigerum, Geoica lucifuga, Acyrthosiphon pisum, citrus roll leaf Aphis citricola), Aphis craccivora, Aphis farinose yaxiagicola, Aphis gossypii, Aulacorthum solani, Brachycaudus helichrysi, Brevicoryne brassicae, tulip Dysaphis tulipae, Euceraphis punctipeimis, Hyaloptems prnni, Lipaphis erysimi, Macrosiphoniella sanbomi, Macrosiphum Euphorbiae), Megoura crassicauda (Vecchio long hair, Vetch aphid), Melanaphis siphonella (Pear Blowing cotton), Apple (Myzus malisuctus), Myzus mumecola, Myzus persicae, onion Neotoxoptera formosana, Ovatus malicolens, and lotus root teeth (^&amp;1〇8丨011111 11113^[^1^6&amp;6), Rice Maicai (Xian (^&amp;1〇81 口一皿11卩&amp;出), Red-bellied rice roots (also Longhorn hornworm teeth, Rhopalosipum mfiabdominalis), Sappaphis piri (Pear roundworm teeth), Schizaphis piricola, wheat longhorn riding cards (such as 〇11 akebiae), Sitobion ibarae, Toxoptera aurantii, Toxoptera citricidus, Tuberocephalus momonis, Ulodeux formosanum, Schizaphis graminum, Dosichacorpulenta, Icerryapurchasi, Crisicoccus matsumotoi, Crisicoccus pini (Japanese pine mealybug), Dysmicoccus wistariae (Pear powder scale insect), Planococcus citri, Planococcus kraunhiae, Orange hip powder scale insect (also orange) Pseudococcus citriculus, Pseudococcus comstocki, Ceroplastes ceriferus, Ceroplastesmbens, citrus crust Coccus discrepans, Coccus hesperidum, Coccus pseudomagnoliamm, Ericerus pela, Lecanium comi, black light Scale insect 145 200836629 (Lecaniumpersicae), Pulvinariaaurantii (Prunus persicae), Pulvinaria citricola (Prunus sylvestris), Pulvinariakuwacola (Sangji scale), Saissetia oleae, Andaspis kashicola (citrus) Scale insects, Aonidiella aurantii, Aonidiella citrina, Aspidiotus destructor, Aspidiotus hederae, brown round Chrysomphalus ficus, Comstockaspis periniciosa, Duplaspidiotus clviger, Lepidosaphes beckii, snail scales (1^&gt;丨(1〇) 8&amp;卩1^ ulπli), Japanese long-stem worm (Lopholeucaspisjaponica), ParlatoΓeopsis pyri (Pear black star scale insect), Camellia Shield scale insect (Parlato Ria camelliae), Parlatoriatheae, Parlatoriaziziphi, Pinnaspis aspidistrae, Pseudaonidia duplex, Pseudaonidia paeoniae ), Pseudaulacaspis pentagona, Pseudaulacaspis prunicola, Unaspis yanonensis, etc.; aphids; COLEOPTERA Adoretus tenuimaculatus (brown tortoise), gold and copper Anomala cuprea, Anomala mfocuprea, Eucetonia pilifera, Eucetonia roelofsi, Heptophyla picea, Melolontha japonica, Mimela splendens , Oxycetonia jucunda, Popillia japonica, Anthrenus verbasci, Attage s unicolor japonicus, Lasioderma serricome, Lyctus bmnneus Flat food worm), Carpophilus dimidiatus, Carpophilus hemiptems (dry fruit golden tortoise, Dried fru It beetle), Epilachna vigintioctomaculata (Big 28), Epilachna vigintioctopunctata, Epilachna varivestis, Alphitobms laevigatus, Neatus picipes Mealworms, Palorns ratzeburgii, Palorns subdepressus, Tenebrio molitor, Tribolium castaneum, Tribolium confusum ), Bean Xianjing 146 200836629

(Epicauta gorhami), Aeolesthes chrysothrix, Anoplophoramalasiaca, Monochamus altematus, Psacothea hilaris, Xylotrechus pyrrhodems, and green-eared beetles (Xystrocera globosa), Acanthoscelides obtectus (Bean weevil), Callobemchus chinensis, Callosobmchus maculatus, Aulacoptiora femoralis, Basilepta balyi, Cassida nebulosa (Small Turtle), Chaetocnema concinna, Colasposoma dauricum (Sweet potato, Sweetpotato leaf beetle), Crioceris quatuordecimpunctata (Fourteen-star long-necked golden flower worm), Donaciaprovosti (rice root) Golden flower worm), Linaeidea aenea (Glass glabrata), Luperomorpha tunebrosa (Yellowfoot golden flower worm),]\^(1;&gt;11 also nigrobilineata (Double Jellyfish), rice worm (Oulema oryzae) ), Pagria signata, Phaedon brassicae, Phyllotreta striolata Leptinotarsa decemlineata (Colorado flower bud), Diabrotica sp. (corn root genus), Involvulus cupreus (Plum chill, Plum borer), Rhynchites heros (Peach curculio), sweet potato ant (Cylas formicarius), Anthonomus pomomm (Apple flower weevil, Ceuthorhyncliidius albosuturalis), Curculio sikkimensis (chestnut i, weevil, Chestnut curculio), rice weevil (Echinocnemus squameus), Euscepes postfasciatus, Hypera nigrirostris (Lesser clover leaf weevil), Hyperapostica, Lisorhoptms orizophilus, Vegetable Weevil (Listroderes costirostris) ), Phyllobius armatus, Sitona japonicus, Anthonomus grandis, Sitophilus oryzae, §itophilus zeamais, turf walking trunk Sphenophrus venatus vestitus, Tomicus piniperda, etc.; yellow stagnation of THYSANOPTERA (Anaphothrips obscums), Chirothrips manicatus, Dendrothrips minowai, Frankliniella intonsa, Lily yellow horse 147 200836629 (Frai linliella lilivora), Heliothrips haemorrhoidalis ), Microcephalothrips abdominalis, Mycterothrips glycines, Pseudodendrothrips mori, Scirthothrips dorsalis, Selenothrips mbrocinctus, Stendchaetothrips biformis ), Thrips alliomm, Thrips coloratus, Thrips flavus, Thrips hawaiiensis, Thrips nigropilosus, Southern yellow horse (Thrips) Palmi), Franklinella occidentalis, Thrips setosus, Thrips simplex, Thrips tabaci, Haplothrips aculeatus, Chinese cockroach Horse (Haplothrips chinensis), Haplothrips kurdjumovi (flower tube hummer), Haplothrips niger (诘草管蓟马), Leeuw Enia pasanii (Vertebra long-tailed hummer), Liothrips floridensis (Lithrips vaneeckei), Lithrips vaneeckei, Litotetothrips pasaniae (Vertebrate round hummer), Ponticulothrips diospyrosi (Persimmon tube hummer), etc.; ORTHOPTERA American Periplaneta americana, Periplaneta fuliginosa, Periplaneta japonica, Blattella germanica, Blattella lituricollis, Homorocoryphus jezoensis Grasshopper), Homorocoryphus lineosus, grasshopper (Gryllotalpa sp.), Oxya hyla intricata, Oxya yezoensis (small-winged rice blast), Locusta migratoria (East Asian locust), etc.; DIPTERA) Tipula aino, Bradysia agrestis, Asphondylia sp., Dacus cucurbitae, Dacus dorsalis, Dacus tsmieonis (Sweet mandarin rope), Rhacochlaena japonica (Cherry fruit fly, Japanese cherry fruit fly), Hydrellia griseola (rice stalk leaf, Smaller rice leaf Miner), Hydrellia sasakii, Drosophila stizukii, Cherryops oryzae, Meromyza nigriventris, Agromyza oryzae, rice leaf miner ), Chromatomyia horticola, Liriomyza bryoniae, Liriomyza 148 200836629 chinensis, Liriomyza trifolii, Liriomyza sativae, South America Liriomyza huidobrensis, Delia antiqua, onion rope, Delia platura, Pegomya cunicularia, Phormia regina, Musca domestica, Culex pipiens pallens (Ajiao sinensis), Anopheles sinensis (Chinese winged mosquito), Aedes albopictus (white-spotted mosquito), underground mosquito (Culex pipiens molestus), etc.; Hymenoptera (HYMENOPTERA), Athalia japonica, Athalia rosae Mficomis (Chamboto sawfly, Arge mali), Arge pagana, Dryocosmus kuriphilus (Chestnut bee, Chestnut gall was p), Formica japonica, etc.; Polyphagotarsonemus latus (tea snail) of ACARINA, Steneotarsonemus pallidus, Tarsonemus waitei, Pyemotes ventricosus P. sylvestris, Penthaleus major, Brevipalpus lewisi, Brevipalpus obovatus, Dolichotetranyclms floridanus, Tenuipalus zhizliilashviliae , Bluvipalpus phoenicis, Tuckerella pavoniformis, Bryobia praetiosa, Bryobiarubrioculiis, Eotetranychus boreus, Eotetranychus geniculatus, Eotetranychus pmni, Eotetranychus sexmanaculatus, Eotetranyclius smithi, Eotetranychus catus, Oligonyclms hodoensis, Oligonychus ilicis , Oligonychus karamatus (larch leaf worm), citrus leaf (Panonychus citr i), Panonychus ulmi (Apple leaf worm), Tetranychus cinnabarinus, Tetranychus kanzawai, Tetranyclms urticae, Tetranyclms viennensis (cherry leaf worm), Acaphylla theae (tea long) Recorded), Aceria tulipae (Tulip rust),

Aculops pelekassi, Aculus fockeui, Aculus schleclitendali, Calacarus carinatus, Calepitrimems vitis, Epitrimems pyri, Eriophyes 149 200836629

Chibaensis (Pear Pseudomonas), Acarns siro (African worm), Aleuroglyphus ovatus (Rizoglyphus robini), Rhizoglyphus robini, Tyrophagus putrescentiae, Omithonyssus bacoti , Leptotrombidium akamushi, Leptotrombidiiim scutellaris, Leptotrombidium pallidum, etc.; Anguina agrostis, Anguinatritici, TYLENCHIDA Ditylenchus destructor, Tylenchorhynchus claytoni, Tylencliorhynchus martini, Tylenchorhynchus sp., Hirschmanniella imamuri, root-rooted nematode (Hirschmanniella oryzae), Pratylenclms coffeae, Pratylenchus convallariae, Pratylenchus fallax , Northern root rot nematode (Pratylenchus penetrans), root rot line Genus (Pratylenchus sp.), Helicotyllenclms dihystera, Helicotylenchus erythrinae, Helicotyllenchus sp., Hoplolaimus sp., Rotylenchulus reniformis, card Scutellonema brachyumm, Bidera avenae, Cactodera cacti, Cryphodera sp., Globodera rostochiensis, scorpion Heterodera elachista, Heterodera glycines, Heterodera trifolii, Meloidogyne arenaria, Meloidogyne camelliae, Meloidogyne graminis, Meloidogyne hapla, Meloidogyne incognita, Meloidogyne sp., Tylenchulus semipenetrans, Aphelenchus avenae, etc.; DORYLAIMIDA Rice dwarf nematode (Longidoms martini), needle Longidoms sp., Xiphinema americanum (American Great Sword line 150 200836629 insect), Xiphinema sp., Trichodoms sp., etc.; THYSANURA sweater fish (Ctenolepisma) Villosa), Lepisma saccharina, silverfish (Ermobiadomestica), etc.; Cryptotermes domesticus, Coptotermes formosanus, Reticulitermes speratus, Taiwan Termites (Odontotermes formosanus), etc.; PSOCOPTERA's book (also known as the powdered tea, Liposcelis bostrychophilus), etc.; SIPHONAPTERA's dog (Ctenocephalids canis), etc.; ANOPLURA

(Pediculus humanus humanus), etc.; Thereuronema tuberculata of the CHILOPODA; Oxidus gracilis of the DIPLOPODA; the mollusk gate (MOLLUSCA) double-chain chain (Incilaria bilineata) and the like. The content of the compound effective for controlling pests in the insecticidal composition of the present invention is usually 0.5 to 20% by weight in the powder, 5 to 50% by weight in the emulsion, ～90% by weight in the wettable powder, and 粒·ΐ in the granules. ~ 2 〇 wt%, water suspension is 1 〇 ~ 9 〇 weight 0 / 〇. On the other hand, the carrier 1 of each dosage form usually has a powder of ～99% by weight, an emulsion of ～95% by weight, a wettable powder of 10 to 90% by weight, a granule of 8〇 to 99% by weight, and a water suspension. The agent is 10 to 90% by weight. Further, the auxiliary dose is usually 1 to 2% by weight of the powder, 1 to 20% by weight of the emulsion, 1 to 2% by weight of the wettable powder, and 0.1 to 20% by weight of the agent, and the aqueous suspension is 〇丨 ~ sink weight%. A pest which occurs by the application of the insecticidal composition of the present invention to a harvest of an agricultural plant. That is, the invention is diluted or suspended with water to control the effective amount of pests, and the storage place of the obtained or agricultural plant harvest is sprayed, coated, smeared, ugly, or pressurized. After harvesting ___) processing ie ^ Chenye plant harvest can be, for example, rice, barley wheat oats, cowpea, kidney beans, slaves, ibem, m bean^ pequxa bean &gt; white bean ^ #-] .^(Lima Bean) ^ . ^ ^ ^ $ . „^nectarine) ^ ^ ^ ^ s^; 151 200836629 Natsudaidai, Wenzhou Orange, Sudachi, Acid Dial, Cabos Orange (CWms, Lime) , lemon, alfalfa, alfalfa (Quince, Μ / (10)), apple, pear, pear, avocado, kiwi, guava, date palm, pineapple, passion fruit, banana, papaya, hazelnut, grass, vine Bilberry, egg bilberry, ^zcdm face ovfl plus m), blackberry, blueberry, persimmon, watermelon, grape, cantaloupe, cantaloupe, no green, broccoli, kale, radish, cabbage, small pineapple (1 variety of rape, edible Rape), water mustard or western cress (cresson, waterCress), kale or kale, horseradish (also Western Mountain) Kwai), red radish (radish), broccoli, simmer (7) 拗, sweet potato, radix radix, taro, potato, pumpkin, courgette, yucca (Cmc_ship/generous (10) face (10)), artichoke (artich〇ke), Endive, Burdock, 21lTfy) f TtT ^1' ^ ^ ^«'' ^ Feng Zhuo (P_P), Xiangxu, Fan Lin, Youzi, Bell Pepper, Lu Tube, Yangmiao, Tuas, points, calendar, window, and a variety of 曰本慧), edamame, autumn ▲, Gan borrow, I,,, two silk: unfinished, beans, immature beans, oil seeds ( Flax, rapeseed, cocoa beans, coffee beans, tea, hops (four), etc., but the seed of the seed, can be in the original form of plants or water or other appropriate dilution or 'the' / away from the Ming, the insect group The amount of the effect is stored in the plant seed or plant seed in the pest control, such as cloth, foam, powder or fumigation fumigation, etc., which is sprayed, smeared, coated by the insecticidal composition of the present invention. It is suitable for the plant and seed produced by the pests produced in the plant after sowing. This prevention is due to the treatment of coating, soaking, powder coating, etc. in the effective amount in the secret species. 2: 琢,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,,, For the breeder, for example, corn, large-wheat, barley, sunflower, pupa, courgette, sage, _f rice, beet, kansui, terminal grass, sweet pepper and edible rapeseed, etc. , such as medicinal sputum, edible lily, compared to sweet potato, the ability to give the production of insecticidal substances, Wangshen = suitable crops, pests and appropriate choice, usually from! ^Use the plant seeds for powder coating, mouth cloth, smear, and the weight of the plant seeds. () 5~5% degree = Special 1: The form of the preparation or the plant species to be treated The insect composition is generally used according to the formula of the party garden turtle, and the preparation is convenient to use. That is, the ns conventional method is prepared by mixing the auxiliary agent with an auxiliary agent in an appropriate ratio, or by immersing, absorbing or adhering to a suspension agent, a core, a mixture, a granule, and a powder. And appropriate dosage forms such as tablets can be used to make small H wettable powders, materials can be exemplified by 2 Ϊ 5 into the core of the carrier, grain flour, flour, cellulose powder, plant essential oil d; 杳 2 powder, resin synthesis, etc. Objects, clays (such as kaolin, soil ^ two ^ broken ^ talc powder (such as talcum powder, pyrophyllite, etc.), chert white clay, etc.), mother, white carbon black [aqueous particles 矽, also known as water-containing people j Bath soil, quartz sand, and cloud 1 contain micro-domains for products. ^活^性矽酸' also algae soil, red brick pulverized material, fly ash, sand, stone mountain, '丨, pumice, burnt 矽 安 安, ammonium silicate, ammonium nitrate, urine + and other inorganic mineral powder, It can be used alone or in combination with chemical fertilizers, composts, etc., which can be used as a liquid inert carrier, except for its own solvent ability. 153 200836629: but with assistance: can be dispersed in the killing ; ί *2 cyclohexanone, etc.) acetone, f ethyl ketone, f isobutyl _, diisobutyl ketone, ethyl vinegar propionate, ί 4 4) 'vinegar (such as ethyl acetate, diced vinegar, =酉曰Special) 'Amidoxime (such as dimethylformamide, decylamine, etc.) 'nitrile (such as acetonitrile, etc.). The auxiliaries of the Τ 曱 曱 曱 曱 , , , , , 。 。 。 。 。 。 。 。 。 。 。 If it is used alone or in combination, it may or may not be used at all; solubilization and/or wetting of the compound which is effective for controlling pests = the surface active agent, for example, polyoxyethylene alkyl bond, poly Oxyethylene burning aryl disaccharide fatty acid vinegar, polyoxyethylene resin _, polyoxyethylene hawthorn, - = Λ月才土酉夂 vinegar, polyoxyethylene sorbitan oleic acid vinegar, burning arsenic acid Lonely, Nai ~! ^ Salt, woody acid salt, higher alcohol sulfate, and the like. , = for dispersion stability, adhesion and / or combination of effective control of pests = 2: auxiliary agents, such as road protein, gelatin, powder, methyl cellulose li i Ala, polyethylene glycol, pine root oil, rice bran Oil, bentonite, dioxin, lignosulfonate, etc. For the fluidity of good solid products, the following auxiliary agents such as soil and hard fat can be used. As the decoagulant for the secret product, an auxiliary agent such as naphthalene sulphate or condensate disc acid salt can be used. Further, the antifoaming agent may be used, for example, as a paste oil, and the insecticidal composition of the present invention is stable to light, heat, oxidation, etc., but may be added with an appropriate amount of an antioxidant or an ultraviolet absorber, such as bismuth (2, 6). - two third 154 200836629 butyl-4 - A), BHA (butyl ketone albino scales) and other benzene derivatives, double hope street creatures, or stabilizers such as phenyl _ 〇: - naphthylamine, benzene An arylamine or a diphenylmethane compound such as a condensed product of an amino group and a non-naphthylamine, and a more stable composition. [Examples] Representative examples of the compounds represented by the general formula (1) or the general formula (5) of the present invention are described below by the following examples, but the present invention is not limited by the examples. [Embodiment 1 - 1],

5 -Amino-6-bromo-8-heptafluoroisopropylquinine 5-Amino-8-heptafluoroisopropylquinoline i.2ig N,N-dimercaptocarboxamide 5ml The solution was stirred in an ice water bath, followed by dropwise addition of 0.69 g of N,N-dimethylformamide 1 〇 ml 2N bromosuccinate. After stirring for 1 hour in an ice water bath and 4 hours at room temperature, ethyl acetate and water were added to the reaction solution, and the organic phase was separated. It was washed twice with water, dried over anhydrous magnesium sulfate and evaporated. The title compound (1.09 g (yield: 72%) of pale brown solid was obtained from the product of &lt;&gt;&gt; Η — NMR (CDC13) δ 4.98(2H, broad — s)? 7.43 (lH dd Τ = 3·9,8·3Ηζ), 8·08 (1Η, (Μ = l.〇HZ), 8.13 (lH, d(i, / ' = 1.558.3HZ), 8.91 (m, dd, J = L5, 3.9 Hz). ,, [Beizhang Example 1-2] N—(6~Bromo-8-heptafluoroisopropyl)啥琳-5-基) 3 - nitro alumine production of 3-nitrophenyl hydrazine. 47g, 5-amino-6-bromo-8-heptafluoroisopropylquinine 1.5g Add 5 ml of pyridine and stir at room temperature. After 5 hours, ethyl acetate and 1N hydrochloric acid were added to the reaction solution, and the organic phase was separated, washed twice with water, and washed with saturated aqueous sodium bicarbonate three times. The solvent was distilled off, and the obtained residue was dissolved in a mixed solvent of 8 ml of tetrahydrofuran and 2 ml of decyl alcohol, and stirred under ice-water bath, 0.10 g of sodium hydroxide was added and stirred for 1 hour, and then stirred. After stirring for 4 hours at room temperature, ethyl acetate and water were added to the reaction solution, and the organic phase was separated and dried over anhydrous magnesium sulfate. The solvent was evaporated under reduced pressure, and the residue obtained was chromatographed by column chromatography. Alkane: 155 200836629 Ethyl acetate = 4 : 1) Refined 'Get the mark Compound 〇72g (yield 52%) white amorphous. iH-NmCCDClO ·4ΐ(ΐΗ4υ=3·9,8·3Ηζ), 7·61(1Η,1^= 7.8Hz) ^ 8J5(lH4dJ=l .5? 83 Hz) 5825 (1811H5sX828 (lH^ 7.8HzX S.39 (lH4J=7.8Hz) 58.84 (lH9s) 58.87 (lH?s)? 8.92 (lH4dJ=1·5,3·9Ηζ). [Example 1 a 3] Ν-(6-bromo-8-heptafluoroisopropylquinoline-5-yl)-3-aminobenzoaniline produced in N-(6-bromo-8-heptafluoroisopropylquin啉 一 5 5 70 70 70 70 70 70 70 70 70 70 70 70 70 70 70 70 70 70 70 70 70 70 70 70 70 70 70 70 70 70 70 70 70 70 70 70 70 70 70 70 70 70 70 70 70 70 70 70 70 70 70 70 70 70 70 70 70 70 70 70 70 70 70 70 70 70 70 70 70 70 70 70 70 70 70 70 70 70 70 70 70 70 70 70 70 70 70 70 70 70 70 70 70 70 70 70 70 70 70 70 70 After being added to the ice water, the insoluble matter which was precipitated after the carbonation was neutralized with celite, and the insoluble material was washed with ethyl acetate, and the filtrate was combined, and the organic phase was separated and dried over anhydrous magnesium sulfate. The residue was evaporated under reduced pressure. EtOAc (EtOAc md. lH, dd, J = l.5, 9.3 Hz), 7.2 〇 - 7.27 (3H, m), 7.76 (lH, d (U = 4.4, 8.8 Hz), 8.4 〇 - 8.43 (2H, m), 9.06 ( l H, dd, J = 1.5, 4.4 Hz), 10.58 (lH, s). [Example 1-4] N-(6-bromo-8-heptafluoroisopropylquinolin-5-yl)3_[(2-fluorobenzyl)amino]benzoquinone (Compound No. 1) A 3〇4) is produced by adding N-(6-bromo-8-heptafluoroisopropylquinolin-5-yl)3-aminobenzimidamide 〇.15g, pyridinium 〇3g to tetrahydrofuran 5 ml and stirred at room temperature, j was added with 2~ fluorobenzhydryl chloride 〇 5 g dissolved in tetrahydrofuran. After stirring at room temperature for 1 hour, ethyl acetate and 1N hydrochloric acid were added, and the organic phase was separated. The organic phase was washed once with a saturated aqueous solution of sodium succinate and dried over anhydrous magnesium sulfate. The solution was filtered, and the filtrate was evaporated. EtOAcjjjjjjjjjj H ~ NMR (DMSO - dg) δ 7.33 ~ 7.40 (2H?m) 57.57 -

7-63(2H5m)57.68-7.73(lH5m)57J7(lH5dd?J=:3.958.8HzX 7.90(lH5dJ 156 200836629=7.8Hz),8.03(m,d,J=7·8Ηζ),8·41 - 8.49 (3H, m), 9.08 (lH, dd, J = 1. 5, 3. 9 Ηζ), 10.70 (m, s), 10.84 (lH, s). ' ' [Example 2 - 1] N - (4 1. Heptafluoroisopropyl-2-oxanyl xanthyl phenyl)-n-methyl 3-succinyl benzamide is prepared by suspending 60% sodium hydride 〇.15g in 4ml of tetrahydrofuran and dropping at room temperature. Add N-(4-heptafluoroisopropyl-2-methylsulfonylphenyl) 3 - Shisha basic amine 1.5g dissolved in tetrahydrofuran. Stir at room temperature for 30 minutes, add dropwise Dissolve in 94 ml of iodomethane oxime of 4 ml of π 夫 喃 。. Next, the temperature is raised to 70 ° C, stirred for 12 hours, and then returned to room temperature, ethyl acetate and water are added to the reaction solution, and the organic phase is separated. After the water was washed once, the residue was dried over anhydrous magnesium sulfate (MgSO4). (yield 64%) light yellow solid. lR _ NMR (CDC13) 5 3.21 (3H, s), 3.39 (3H s), 7, 64 (m, d, J = 8.3 Hz), 7.73 (lH, t, J = 7.8 Hz), 8.03 (lH, d, J = 8.3 Hz), 8.07 (lH, d, J = 7) · 8Ηζ), 8.38-8.41 (2H, m), 8.55 (lH, s) [Example 2 - 2] N-(4-heptafluoroisopropyl-2-methyl-stone phenyl)-N- Manufacture of fluorenyl 3-aminobenzamide, N-(4-pentafluoroisopropyl-2-methylsulfonylphenyl-methyl 3-nitrobenzidine S&amp;fec 0.93g, gasified tin (1) (anhydrous) i 4 g was added to 20 ml of ethanol, followed by dropwise addition of 2 ml of concentrated hydrochloric acid. After the addition, the temperature was raised to 60 ° C, stirred for 15 hours, and the reaction solution was poured into ice water. After the neutralization operation, ethyl acetate was added, and the insoluble matter of the mash was filtered off with diatomaceous earth. The filtrate of the diatomaceous earth was washed thoroughly with ethyl acetate. The organic phase of the filtrate was separated and dried over anhydrous magnesium sulfate. The solvent was evaporated under reduced pressure, and the residue was purified mjjjjjjjjjjjjjjj Η - NMR (CDC13) 5 3J9 (3H5s) 339 (3as) 93.88 (2H5broad -

sX6.80(lH?d9J = 7.8Hz)?6.96(1H,s)?7.〇4( lH?dJ = 7-8Hz)?7.26(1H5U = 7.8I^z), 7.60(m,d,J = 7.8 Hz), 7.99 (m, d, J = 7.8^) 5 M^ [Examples 2 to 3] N-(4-heptafluoroisopropyl-2-methylsulfonylphenyl)-n 200836629 1) Purification 'The title compound 〇. 38 g (yield 14%) was obtained. [Comprehensive Example = -2] 2,4,6-Sanmo-3-(seven-l-n-propylthio)aniline was produced by adding heptafluoro-n-propylthio)aniline oxime 38g to N,N_ To a solution of dimercaptoamine in 10 ml, ruthenium bromide succinimide J2g was added. At 6 〇. After stirring for 2 days, add ether and water and separate the organic phase. After the organic phase was washed twice with water, the mixture was dried over anhydrous magnesium sulfate, and the solvent was evaporated under reduced pressure. The residue was purified by silica gel column chromatography (hexane: ethyl acetate = 8:1). The title compound 〇. 6 yield 89%)

iH-NMRfDC^) d 4.87 (2H, s), 7.83 (1H, s). [Culture Example 5-3] N-{2,4,6-Tri-Methyl-3-(Seven-D-Pro-propylthiophenyl 3-s-succinylbenzamide) 2,4,6-tribromo 33-(heptafluoro-n-propylthio)aniline oxime 61g, 3-nitrophenylhydrazine chlorohydrazine. 43g was added to pyridine 20ml, stirred at 7〇t: for 2 hours, then added ethyl acetate and water The reaction solution was separated, and the organic phase was separated and dried over anhydrous magnesium sulfate. The filtrate was filtered, the filtrate was collected, and the solvent was evaporated under reduced pressure, and the residue was purified by column chromatography (hexane: ethyl acetate = 4) : 1) To give the title compound 〇. 69 (yield: 89%) as a white solid. ???H-NMR (CDC13) (5 7.76 (1H^J=7.8Hz)JJ8(1H5s)?8.15(1H9s)583 2 lH, d, J = 7.8 Hz), 8, 47-8e50 (lH, m) 58 J9 (m, s) [Scheme 5-4] N-{2,4,6-tribromo-3-( Heptafluoro-n-propylthiophenyl-phenyl-3-aminobenzamine is produced by using 1{2,4,6-tri-di-3-(heptafluoro-n-propylthio)}phenyl 3-nitro Awkward, 0.69g of decylamine, anhydrous of tin (I) chloride (X6〇g is added to 2〇ml of ethanol and stirred at room temperature / gluten, 1 ml of hydrochloric acid is added, heated and stirred at 60 ° C 2 hours. After returning to room temperature, it will be reversed The solution was poured into water and neutralized with potassium carbonate. After adding ethyl acetate to remove the insoluble matter, the organic phase was separated and dried over anhydrous magnesium sulfate. The solution was filtered, and the filtrate was collected under reduced pressure. Distilled, it will be burned and cleaned, lion compound 0.62g (fresh 94%) self-color e (CDC13) 5 3.89 (2H9s) 56.89 (lH4t? J = 6.4? 2.4Hz)? 7.27 ^ 160 200836629 Example 2 - 2 The title compound was prepared (yield: 97%). NMR^DC^) δ 3.53 (2H9brs) 56.40 (lH5septet?J = 6.4 Hz) 56.77 (lH, d, J = 8.8 Hz), 7.09 (m, Dd, J = 2.9, 8 · 8 Ηζ), 7 · 60 (lH, d, J = 2.9 Hz) [Example 6 - 3] 6 - bromo-5-amino 2 - (2, 2, 2 - Preparation of trifluoro-i-trifluorodecyl ethoxy) ruthenium iridium 5 5-amino-2 - 2,2,2-trifluoro-1,3-trimethylol ethoxylate than 2.0g 15 ml of N,N-dimethylformamide, and adding 1.36 g of N-bromine acid at room temperature. After stirring at room temperature for 2 hours, ethyl acetate was added and washed with water. After drying in the US, it was refined by Shixi rubber column chromatography (positive hexane: ethyl acetate = 1 〇: 1) to obtain the title. Oil compound 2.35g (yield: 90%). H-NMR (CDC13) 5 3.92 (2H, brs), 6.23 (lH, septet, J = 7.4 Ηζ), 6.77 (lH, d, J = 8.3 Hz), 7.12 (lH4, J = 8.3 Hz). ^ [Example 6 - 4] N - [2-bromo-4-iso(2,2,2-trifluoro-1,3-trifluorodecylethoxy)-anthracene 3-amino]3~nitrobenzene Preparation of guanamine using 6-, 5- 5-amino-2-(2,2,2-trifluoro-l-trifluorodecylethoxy) pyridine, according to the conditions described in Example 1-2 The title compound was produced (yield · 92%). 'H-NMRCCDCls) (5 631 (IH.septeU = 5.8Hz) 97.06 (1H5cU = 8.8Ηζ), 7·77 (lH, t, J = 8·3Ηζ), 8·25 - 8·29 (2 H, m), 8.47 - 8·50 (lH, m), 8.77 - 8·8 2 (2H, m) [Example 6-5] NH-4_(2,2,2,3-tris-trifluoromethane Manufacture of ethoxy)-formyl-3-yl]benzamide amide N-[2-bromo-4-(2,2,2-trifluoroη-trifluorodecylethoxy)-pyrene The title compound (yield · 81%) was obtained according to the conditions described in Example 3 using the 3-nitrobenzoic acid amine. (M-NMR NMRCls) (5 3.90 (2H5brs)? 6.29 (lH5septetJ = 5.9 Hz) 56.88-6·91 (1Η, πι), 7·00 (lH, d, J &gt; 8 8Hz), 7 21 - 7 32 (3Η, πι), 8·23 (lH, brs), 8.85 (lH,d,J=8.3Hz) 0 Production [Implementation=6-6] N-[2~Fill a 6-(2,2,2-tri-u-three-trimethylthio)ethoxylate Manufacture of -3-yl]L (stupylmethylamino)benzamide (Compound No. i 162 200836629-387) Using N-[2-bromo-6-(2,2,2-trifluoro-1) -trifluoromethylethoxy)pyridin-3-yl]3-aminobenzamide and gasified benzoquinone, according to the article of Example 1 The title compound was obtained (yield: 76%). 4-NMR (CDC13) (5 630 (lH, septet, J = 6.8 Hz), 7.01 (lH, d, J = 8.8 Hz) J.49 - 7.61 (4H?m) 97.68 (lH5dd5J = L0J.8Hz) 57.88 - 7.91 (2H, m), 7.96 - 8.01 (2H, mX8.26 (lH, t, J = 1.9Hz), 8.33 (lH, s), 8 , 81 (lH, d, J = 8.8 Hz) [Example 7-1] N-(2-bromo-6-fluorenyl- 4,3-trimethylsulfonyloxybenzene-yl)3-nitrobenzene Preparation of guanamine The preparation of guanamine according to the method described in Example 1-i is carried out according to the method described in Tetrahedronl 2263-12276 (1995) using the synthesized 2-indolyl-4-(trimethylethenyloxy)aniline. -Bromo-6-fluorenyl-4-(trimethylethenyloxy)aniline, and the title compound was obtained (yield: 52%) according to the conditions described in 1-2. 々·NMRCCDab) 5 1.36 (9H, s), 2.36 (3H, s), 7.00 (lH, d, J = 2.0 Hz); 7.27 (m, d, J = 2.0 Hz), 7.65 (m, bL), 7.74 (m, U = 8.3 Hz), 8.31 (lH, dd, J = 1. 5, 6.3 Ηζ), 8.44 - 8.47 (lH, mX8.79 (lH5t, J = 2·0Ηζ) 〇% [implementation Example 7 - 2] Ν-(2 - bromo-6-fluorenyl-4-tetrahydroxyphenyl) 3-aminophenyl phthalamide is produced by N-(2-bromo-6-methyl-1,4-31 Ethyl ethoxy phenyl) 3-nitrobenzamide and aqueous sodium hydroxide solution were added to decyl alcohol and stirred at 7 ° C for 3 hours. The solvent was removed under reduced pressure to give the residue as acetic acid. The ethyl ester was dissolved, washed with a 2N aqueous solution of hydrochloric acid, and then dried over anhydrous magnesium sulfate, and the solvent was evaporated under reduced pressure. The residue obtained was purified by column chromatography (n-hexane: ethyl acetate = 1 · 丨) The title compound (yield: 97%) was obtained from the title compound (yield: 97%). , ^ [, Example 7~3] N-(2-bromo-4-hydroxy-6-methyl-phenyl)-3-monophenylphosphonylbenzamide Manufacture (Compound No. 1-484) 163 200836629 Using N-(2-Nyphos-6-methyl-4-tetrapyridylphenyl)3-aminobenzamide, the title was produced according to the conditions described in Examples 1 to 4. Compound (yield 95%). ^-NMRf DMSO-d6) δ 2.16 (3H, s), 6.72 (1H, d, J = 2.4 Hz), 6.94 (lH, d, J = 2·4 Ηζ), 7· 50 — 7.63(4H,m), 7.74(lH,d,J = . 8·3Ηζ), 7.98 — 8.05(3H,m), 8.32(m,s),9.79(m,s),9.81( lH, s), 10.4 (m, s). [Example 7-4] Manufacture of N-(2-bromo-6-methyl-4-tetrafluoromethanesulfonyloxyphenyl)3-(phenylhydrazino)phenylamine (Compound) No. _369) N-(2-bromo-6-fluorenyl-4-hydroxyphenyl)3-(phenylhydrazinoamino)benzoquinone 0.2g and trifluorosulfonium ruthenium anion 〇j4g was added to η to bite and stirred for 7 hours. The solvent was evaporated under reduced pressure. EtOAc m. !H-NMR( DMSO-d6) 5 2.32(3H?S)?7.52 - 7.63(5H5m)?7.76(lH5(U=7.8Hz)57.87(lH?d?J=2.7Hz)58.00(2H?dd? J=l-557.8 Hz)?8.06 (lH5d?J=7·8Ηζ), 8.37 (1H, s), 10.18 (1H, s), 10.47 (1H, s) o [Example 7-5] N — [2-Bromo-O-methyl- 4-(p-pfite xantheneoxy) phenyl]3-(benzhydrylamino)benzamide (manufacturing number! 485) N-(2-bromo-6-fluorenyl-4-hydroxyphenyl) 3 -(phenylhydrazinoamino)phenylhydrazine &amp;&amp;&amp;&gt;amine 0.30g, 1,1,1,3,3,3 — Six gas isopropyl p-toluene yellow acid series 23.23g, carbonic acid decanting 0.19g, 18-crown one 6 ether 0.03g added to N, N-dimercaptocarhamamine 5ml, stirred at 70 C: fell 6 Adding acetic acid to the 100 ml of water to wash with water (5 〇mlx2). The organic phase is dried over anhydrous magnesium sulfate. The solvent is removed under reduced pressure, and the residue obtained is chromatographed on a chopping column (n-hexane·· Ethyl acetate = 3:1) to give the title compound (5 g) (yield: 13%) 〇'H NMR (CDC13) δ 2.29 (3H, s), 2.48 (3H, S), 6.94 (1H, d, J = 2·9Ηζ), 7·14 (lH, d, J = 2.9Hz), 7.36 (2H, d, J = 8·3Η) ), 7'·51 — 7·61(5Η,ιη),7·71 - 7.77( 3H,m), 7.88 a 7.92(3H,m),7.99(lH,br.s)58.28(m,s) [Example 8.1] N-(2,6-dimethyl-1,4-pentafluoroisopropyl)phenyl 3-nitrate 164 200836629 Benzobenzamide is produced by using 2,6-didecyl 4-4-Hexafluoroisopropylaniline 2〇.〇g, η than bite n 〇g was added to tetrahydrofuran 100ml and stirred at room temperature, slowly adding 3ml of nitrobenzene dissolved in tetrahydrofuran 20ml醢Chlorine 13X)g. After stirring at room temperature for an hour, ethyl acetate and water were added to the reaction solution. After the liquid separation operation, the organic phase was separated and dried over anhydrous magnesium sulfate. The solution was filtered, and the filtrate was evaporated. EtOAcjjjjjjjjjjjj ^NMRCCDCls) 5 2.33(6H5s)97.37(2H?s)57.68(lH?s)?7.72(lH?t?J=8.1Hz)58.28(lH?d?J=8.1Hz)?8.44(lH5dd?J= L2? 8.1 Hz) 58.75 (lH5t5J = 1.2 Hz) ' ' ' [Example 8 - 2] N-(2,6-dimethyl-1,4-heptafluoroisopropyl)phenyl 3-aminobenzamide The amine is produced by adding N-(2,6-dimercapto-tetrakisylfluoroisopropyl)phenyl 3-nitrophenylamine 〇.90g, tin chloride (I) anhydrate 1.56g· A solution of 25 ml of ethanol and stirring at room temperature was added to 2 ml of concentrated hydrochloric acid, and stirred at 60 ° C for 1 hour. After returning to room temperature, the reaction solution was poured into water, and neutralization was carried out using potassium carbonate. After adding ethyl acetate and filtering off the insoluble material, the organic phase was separated and dried over anhydrous magnesium sulfate. The solution was filtered, and the filtrate was evaporated. EtOAcjjjjjjjjjj ^-NMRCCDCls) δ 2.34(6H?S)3.87(2H?broad)?6.86 - 6.89(lH5m)57.20-7 35(6H5m) [Example 8-3] N-[2,6-dimethyl-4 Production of mono(heptafluoroisopropyl)phenyl]3-mono(4-nitrophenylamino)benzamide (Compound No. 5-9) will be N — (2,6-dimercapto-4-one Heptafluoroisopropyl)phenyl 3 -aminobenzimidamide 〇.3g, 4-bromonitrophenylhydrazine. 18g, 9,9-dimethyl- 4,5-di(diphenylphosphine) 21 mg and 0.29 g of cesium carbonate were placed in a reaction vessel, and stirred under a nitrogen stream at room temperature for 15 minutes. After 6 mg of palladium acetate was added, the mixture was reacted at 9 ° C for 6 hours in a nitrogen atmosphere. After cooling to 165 200836629, the temperature was added. Ethyl acetate was washed with water, dried over anhydrous magnesium sulfate, and the solvent was distilled off under reduced pressure, and the residue obtained was purified by column chromatography (n-hexane·ethyl acetate = 1 0 : 1-8) ·· 2-2 ·· 1) Purification, the title compound 〇16g (yield 74%) * yellow crystals.

^-NMRCCDCls) 2.36 (6H, s), 6.50 (lH, brs), 7.02 (2H, d, J = 8.7 Hz) J.38 (2H5s)? 7.42 (1H?s) 57.46 (1 196H? (U = 7.8 Hz)? 7.53 (1H5U = 7·8 Ηζ), 7·60 (lH, d, J =: 7.8 Hz), 7.91 (lH, brs), 8.19 (2H, d, J = 8.7 Hz). [Implementation ^9-9] [3 - [(2,6-dimercapto-4-tetrafluoroisopropylphenyl)amino]yl]benzyl]4-chlorophenyl; (Production of Compound No. φ produced by the implementation of j 8-2 Ν-(2,6-didecyl- 4-7 fluoroisopropyl)phenyl 3-aminobenzamide oxime. 30 g added to pyridine 5 m 4 g of 4-chlorobenzenesulfonyl chloride was placed in a solution of 1 and stirred at room temperature for 2 hours. Then, ethyl acetate was added, and then poured into ice water. The aqueous phase was made acidic using &gt; The organic phase was separated, washed twice with saturated aqueous sodium hydrogen sulfate solution and dried over anhydrous magnesium sulfate. The solvent was evaporated under reduced pressure, and the residue was purified by column chromatography (hexane: ethyl acetate = 2) : 1) Refining to give the title compound 0.30 g (yield: 70%) of a color of amorphous material. 'H. NMR CCDCls) 5 2.29 (6H5s) ? 7.32 - Ί. 39 (6H?m)? 7.58 - 7.66 (6H, m) [Example 10-1] 4-(1,1,2,3,3,3-hexafluoropropoxy)-nitrobenzene was prepared by p-nitrophenol 4.63 g and potassium hydroxide 0 56 g After adding hexafluoropropane to a solution of N,N-didecylguanamine lOjril, it was stirred at 5 (rc for 1 hour). Then, after adding ethyl acetate and water, the organic phase was separated. The organic phase was dried over anhydrous sodium sulfate, and the solvent was evaporated, evaporated, mjjjjjjjjj 42%) yellow oil. H-NMR (CDCls) δ 5.06 (lH5ddtJ=44.05lL255.2Hz) 57.39 (2H?d5J = 8·8Ηζ), 8·30 (2H, d, J = 8.8 Hz). Example 10-2] Preparation of 4~(U,2,3,3,3-hexafluoropropoxy)monoaniline 甩4(1,1,2,353,3~hexafluoropropoxy)-nitrogen The title compound was obtained as an oil of the title compound (CDCI3) δ 3·69 (2H, brs), 4·% (lH, dddcU = 44·0, 11·········· 2, 11.2, 5. 6 Ηζ), 6.64 (2H, d, J = & 8 Hz), 6.98 (2H5d, J = 8.8 Hz). [Example 10-3] Preparation of 2,6-dibromo-4-iso(1,1,2,3,3,3-hexafluoropropoxy)-aniline using N-bromo acid to make imine 2 equivalents The title compound oil was obtained according to the conditions described in Example 1-1. 'H-NMR (CDCI3) δ 4.51 (2H, brS), 4.96 (lH, dddd, J = 44·0, 11·2, 11·2, 6·0Ηζ), 7.30 (2H, s) 0

[Example 10 - 4] N-(2,6-dibromo- 4 -(1,1,2,3,3,3-hexafluoropropoxy)phenyl)-3-nitrophenyl hydrazone The title compound solid was produced according to the conditions described in Example 1 and 2. Ή-NMR (CDCI3) δ 5.01 (lH?brd9J = 44.0Ht;) 57.52 (lH s)7 57 - 7/78 (2198 Η, πι), 8·13 (lH, d, J = 7.6 Ηζ), 8 ·32 — 8·38 (2Hm)8 65 (lH,s) 〇,,.

[Example 10-5] Ν-(2,6-dibromo-4-iso(1,1,2,3,3,3-hexafluoropropoxy)phenyl)3-aminophenylamine The title compound solid was obtained according to the conditions described in Example 1 to 3. 'H-NMR (DMSO - d6) (5 5.18 (2H?brs)?626 (lH?brdJ = 44,0HzX6.80 (lH9dJ=6.4Hz) 57.14 (2H5tJ=7e 6Hz) 57 20 ΠΗς^7 6λ (2H , s), KU4 (lH, s). V 9 Λ [Example 1 ()-6] N-(2,6-dibromo-4-(-, 151, 2, 3, 3, 3 - hexa) 3-[(2-Fluorobenzoyl)amino]benzamide (Compound No. 2, phantom was produced according to the conditions described in Example I-4 to give the title compound H-NMR (CDCI3) 5 5.01 ( 1H, brd, J==4 4.0Hz), 7 HdJ_ 8.0 Qing.42 _, Bu 7 is enough, 7·52_7'55 ( =: 7.6Ηζ), 7.δ2 one (4H, d, J==8, 0 Hz), 8, 02 (2H, S), 8 25 (2H j), 八邱, followed by a representative scheme of the present invention, but the present invention is sparsely used. Further, 167 200836629 In the preparation example, "Parts" means "parts by weight." Formulation Example 1 (Powder) 5 parts of compound 2-167 and 94.5 parts of clay and Driless B (Sankyo Co., Ltd.) 5 parts were uniformly mixed and pulverized to obtain 5% of active ingredient. Formulation Example 2 (Wettable powder) 50 parts of Compound 1 - 306, 1 part of lignin, 1 part of white smoke, and 44 parts of Shixia Earth are mixed and pulverized to obtain 50% of active ingredient. Wet powder Formulation Example 3 (aqueous suspension) 20 parts of Compound 1 - 187, 5 parts of propylene glycol, 5 parts of polyoxyethylene oleate, 5 parts of polyoxyethylene diallyl ether sulfate, 0.2 parts of an antifoaming agent, and 64 parts of water, wet-grinding with a sand mill to obtain an aqueous suspension of 20% of the active ingredient. Formulation Example 4 (emulsion) 10 parts of compound 2-167, 10 parts of cyclohexane, 60 parts of diphenylbenzene, And 2 parts of Sorpol (manufactured by Toho Chemical Co., Ltd.) were uniformly dissolved and mixed to obtain an emulsion containing the active ingredient of 1 〇 0 /. Formulation Example 5 (Particle wettable powder) 20 parts of Compound 1 - 3 〇 6, 3 parts of CMc sodium, 5 parts of alkyl sulfate, and 72 parts of clay are uniformly mixed, and then mixed with water, granulated, dried, and granulated to obtain a granule wettable powder containing 20% of the active ingredient. The biological test of the present invention is shown below. In the following test examples, a wettable powder was prepared in the same manner as in Formulation Example 2 except that the compound described in the Table was used, and an aqueous suspension was prepared in the same manner as in Preparation Example 3. [Test Example 1] The control effect on the leaf beet of the beet will be selected as the dose of the wettable powder as a seed. Clothing (dressing) machine (in the rotating drum body ^ chemical spray solution) processing for 45 days, check the cause of the food leaves flea extent of damage was calculated and Prevention said two's rate. In addition, the presence or absence of phytotoxicity can also be investigated with the naked eye. The results are shown in Table 6. The degree of eclipse and index are as follows: Index 0: no food, index 1: less taint, 200836629 index 2: degree of eclipse, index 3: degree of eclipse prevention = 100-((lx index 1 of the number of food + 2x) Index 2 number of foods + 3χ index 3 number of foods) / 3χ total number of surveys xlOO) Table 6 dose of test agent (g ai/100000 seeds) control rate (%) phytotoxic compounds 6-12 50 99 benefits #,, , dinotefuran 50 99 benefit no treatment area ----- 0-- Ml --------

h type 3 for the control effect of red bean weevil ^ ΐΐϊϊΐ水, for the red bean 1kg 20ml smear treatment. After air drying, 3 ^ knives, south of the petri dish, and placed in the pit strange greenhouse. Process 2, and complex). On the 2nd day, the early adult worms were fed 1 〇 in each high-waist petri dish (5 results were calculated as the number of dead touches and the number of red beans in the week, and the mortality rate was calculated. Number of dead insects in the area / 50) χι〇〇169 200836629 Table 7 Dosing amount of test agent (g ai / kg seed) Dead insect rate after 3 months of treatment after 2 months of treatment (%) Number of eggs laid /竿 only dead insect rate (%) number of eggs laid / 竿 compound only 1-306 5 100 0 100 0 compound 2-163 5 100 0 100 0 compound 6-8 5 100 0 100 0 compound 6-12 5 100 0 100 0 Datnam 5 100 0 100 0 No treatment area 0 12.0 0 11.5 [Test Example 3] Corn phthalocyanine control experiment The selected amount of wettable powder was subjected to powder coating treatment for 5 g of corn seeds.钵 Seeding 5 seeds treated with the drug, 10 seeds of the 3rd instar larvae of the genus Spodoptera were placed after 9 days of sowing, and the net was hanged (2 repeats). After 5 days of larvae, the life and death were checked, and the mortality rate was calculated. Shown.

170 200836629 Table 8 Dosing amount of test agent (mg ai/seed) Dead insect rate (%) Phytotoxicity compound 1-159 20 100 Benefit compound 1-306 20 100 No compound 2_159 20 100 No compound 2-163 20 100 None Compound 4-1 20 100 No compound 5-9 20 100 No compound 6-8 20 100 No compound 6-9 20 100 No compound 6-12 20 100 Unidacloprid 20 100 No treatment zone 10 No [Figure Simple description] no 0

[Main component symbol description] None. 171

Claims (1)

200836629 X. Patent application scope: Ν ( 1. -, the insecticidal composition of the plant seed, which is characterized by ^ί) (1) The compound of the compound 1 thief 2 is used as a riding effect component: (1) |2 (Χ)η Α: ττ R: % {wherein ^, A2, A3, A4 each represent a carbon atom, a nitrogen atom or an oxygen group R!, R2 independently of each other to represent a hydrogen atom, C1-C4 wire, C1-C4 =, Gi, 〇2 are independent of each other to represent an oxygen atom or a sulfur atom; 兀火土, = is a different thief of the thief's money atom, ^ atom, ci-c3 or trichloro η represents an integer from 〇 to 4; Phenyl, substituted phenyl: having a halogen atom, a C1-p alkyl group, a substituted C1-C4 top group, a C2-C4 age f group C1 - C4 * ^ C2-C4 ^ C2-C4 . C3- C ^ ' group, a-C3 alkoxy group, C1-C3 oxy group, = calcined C3 haloalkylthio group, C1-C3 fluorenyl arsenite group dioxin _ xanthine group, C1 - C3 _4C3C1_= group, a -C4 amine group, amine group, aryl group, schlossyl group, Cl C4, -C4 halogen group, C1-C4 carbonyloxy group, C1, C4 group, C1 C4 alkoxy group, C1-C4 halogen group , C1~C4, heart haloalkylcarbonylamine, C1-C4 silk stone fit a carboniferous ring group of the same or a non-anthracene group of the above-mentioned substituents of a sulfonium sulfonate, a pentafluorosulfide wire, a pentafluorosulfide wire, or a benzynyl group (wherein the carboniferous ring wire represents a naphthyl group, a tetrahydrocaline group, a Nitrogen, base, 172 200836629 9-side oxyalkyl, adamantyl, fluorenyl or fluorenyl), substituted carbocyclyl having a halogen atom, C1 - C4 alkyl, C1 - C4 haloalkyl, substituted C1 - C4 alkyl, C2 - C4 alkenyl, C2 - C4 haloalkenyl, C2 - C4 alkynyl, C2 - C4 haloalkynyl, C3 - C8 cycloalkyl, C3 - C8 Halocycloalkyl, C1-C3 alkoxy, C1-C3 haloalkoxy, C1-C3 alkylthio, C1-C3 haloalkylthio, Cl-C3 alkylsulfinyl, C1_C3 haloalkyl Sulfonyl, Cl—C3 alkyl, decyl, C1—C3 haloalkyl, decyl, C1-C4 alkylamino, di-C1-C4 alkylamino, amine, cyano, nitro, hydroxy, C1 —C 4 alkylcarbonyl, C 1 —C 4 haloalkylcarbonyl, C 1 —C 4 alkylcarbonyloxy, C 1 —C 4 halocarbonyloxy, C 1 —oxygenoxy, C 1 —C 4 —oxygenoxy, ci—C 4 , C1 - C4 haloalkylcarbonylamine, C1 - C4 alkyl sulfonate One or more substituents of the same or different ones of the oxy group, the ci-C4 haloalkyl fluorenyloxy group, the &amp;&oxy group, the pentafluorosulfanyl group, the phenylalkyne group or the phenyl group (the carbocyclic ring here) The group represents a naphthyl group, a tetrahydronaphthyl group, a dihydroindenyl group, a fluorenyl group, a 9-side oxyindenyl group, an adamantyl group, a fluorenyl group or a reduced box group, and a heterocyclic group (wherein the heterocyclic group represents a pyridyl group) Tillage, pyridyl, N-oxypyridyl, pyrimidinyl, hydrazine, furyl, thienyl, carbazolyl, iso-oxazolyl, oxadiazolyl, thiazolyl, isothiazolyl, thiadiazole , pyrrolyl, imidazolyl, triazolyl, oxazolyl, tetrazolyl, benzothiazolyl, benzoxazolyl, benzofuranyl, benzothienyl, yl, isoquinolinyl, anthracene Base, isoindole, 1H-isoindolyl, 23-hydrogen-benzo[1,4]dioxin (2,3_dihydr〇7 (10)叩州(五)邮), benzo-U, 3] Carbazolyl (benzo[l,3]diox〇lyl), tetrahydropyranyl (te her ydrop^anyi), acridinyl (acridinylu substituted heterocyclic group) having a halogen atom, C1 - C4 alkyl group , C1_C4 ^ base, substituted C1 - C4 炫, C2-C4 secret C2_C4 _ group, -C4 fast group, C2-C4 haloalkynyl group, C3-C8 cycloalkyl group, C3 - C8 halocycloalkane di C1 - C3 alkoxy group, C1 - C3 * decyloxy group, C1-C3 burning Sulfur-based,. 1-", Cl-C3 alkylidene, α-C3 sulfinyl, rd ίί sulfonyl, C1 monohaloalkylsulfonyl, C1-C4, di-, dimethyl, amine Base, cyano group, nitro group, thio group, C1-C4 carbonyl group, C1 173 200836629 ϊϊ ϊϊ C C 4 几 几 、 、 、 、 、 、 C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C C The base group, C1_C4 ^ L4 alkyl decyloxy group, Cl-C4 dentate sulfonyloxy group, heterocyclic group, one of the thieves of the thief is different (4) Λ, 々 四 (4) based "嚏 嚏, Ν - oxidation吼唆基, Γ ^&quot; ^, °夫基基, ° thiophene, Jin Junji, 异 嗤 、, 今 嗅 也 装 /, thiazolyl, thiadiazolyl, pyrrolyl, imidazolyl , triazolyl, benzofuran, stupid, benzoxanthyl, benzo? soil, ^^ soil, isoindole, phenyl, hetero, phenyl, 1 Η-metaphor a group, a base, a material [1,3], a hepta, a tetrahydronium group, a watch and a carbon ring group (wherein the carbocyclic group represents a naphthyl group, a tetrahydronaphthyl group, a C3-C8 coat, a factory wind Base, base, 9-side oxy group, adamantyl or depressurized base) From a halogen atom, a C1_C4 alkyl group, a C1-C4 halogen group, a substituted C1-C4 alkyl group, a C2-C4 alkenyl group, a C2-C4 halogen group, a 2-C4 block group, a C2-C4 haloalkynyl group, C3 — C8 cycloalkyl, C3 _ c8 tooth ring burned earth, Cl—C3 alkoxy group, Cl—C3 _ alkoxy group, C1-C3 alkylthio group, α~C3 halogenated sulfur group, C1-C3 alkyl group Sulfonic acid group, C1-C3 self-calcining chloromethane group, C1-C3 alkyl fluorenyl group, 01-haloalkylsulfonyl group, indenyl 4-alkylamine group, di-C1-C4 alkylamino group , cyano, nitro, hydroxy, C1_C4 alkylcarbonyl, ci — q ^ alkylcarbonyl, Cl—C 4 alkylcarbonyloxy, ci—C 4 —alkylcarbonyloxy, ci—C 4 alkoxy, C1-C 4 halo Oxycarbonyl, C1-C4 alkylcarbonylamino, C1-C4 S alkanoamine, C1-C4 alkylsulfonyloxy, C1-C4 haloalkylsulfonyloxy, aryloxyx, pentafluorosulfur One or more substituents which are the same or different among the alkyl group or the phenyl group (the carbocyclic group here represents a naphthyl group, a tetrahydronaphthyl group, a C3 - C8 cycloalkyl group, a dihydroindenyl group, a mei, a 9 side) Oxyfluorenyl, adamantyl or ruthenyl), a heterocyclic ring (herein a heterocyclic group means oxime, 吼π Stationary, N-oxidation.] 定美, pyrimidinyl, hydrazine, furyl, thienyl, carbazolyl, iso, oxazolyl, fluorenyl, thiazolyl, isothiazolyl, oxadiazolyl, pyrrolyl , imidazolyl, triazolyl, 174 200836629 oxazolyl, tetrazolyl, benzothiazolyl, benzoxazolyl, benzofuranyl, benzoindol, quinolyl, isoquinolinyl,丨, 吲哚, 1, 1, 1, 1, 2, 2, 2, benzo[1,4] 噚 噚, benzo[1,3] Chen, Nan Tomb, - Benzomidino or dihydros-sulphuryl), ~ Substituted heteroxyl group · Has a halogen atom, C1 - C4 alkyl group, ci - C4 halogen group, substituted C1 - C4 alkyl, C2 - C4, C2 - C4 from rare, C2 - C4 alkynyl, C2 - C4 haloalkynyl, C3 - C8 cycloalkyl, C3 - C8 halocycloalkyl, Cl - C3 Oxygen, Cl-C3 halogen alkoxy, (^1~〇3 sulphur-based 1 (^1-C3 halogen-burning thio group, Cl-C3 alkyl sulphate, Cl-C3 halogen-based sulphite) Base, _ C1 - C3 burnt stone scutellaria, Cl - C3 halogenated sapphire yellow wine base, Cl - * C4 burned amine base , C1—C4 amine group, cyano group, nitrate group, thiol group, Cl—C4 group, ci—C4 halocarbonyl group, Cl—C4 alkylcarbonyloxy group, Cl—C4 halocarbonyloxy group, C1 — C4 alkoxycarbonyl, C1—C4 haloalkoxycarbonyl, Cl—C4 alkylcarbonylamine, Cl—C4 halogenated amine, Cl—C4 alkyloxy, C1—C4 halogen compound One or more substituents which may be the same or different among the methoxy group, the pentafluorosulfide group or the phenyl group (herein, the heterocyclic group represents a sputum base, a bismuth bite a 2-base, a hydrazine 4-based, N-phosphonium sulfonate, pyrimidinyl, hydrazine, furyl, thienyl, carbazolyl, isoxazolyl, oxadiyl, thiazolyl, isothiazolyl, thiadiazolyl, Pyrrolyl, imidazolyl, triazolyl, _ ° biszolyl, tetrazolyl, benzothiazolyl, benzoxazolyl, benzofuranyl, benzothiophene, quinolyl, isoquinolyl, Sulfhydryl, isodecyl, 1 Η- 异 嗓 、, 虱 苯 benzo[Μ] 二今, benzo[1,3]dioxin, tetrahydropyranyl, benzo Imidazolyl or dipyridyl), C1 - C6 alkyl, C1 - C6 alkyl: having a halogen atom, C1 - C4 haloalkyl, C2 - C4 alkenyl, C2 - C4 - alkenyl, C2 - C4 alkynyl, C2 - C4 haloalkynyl, C3 - C8 ring Burning base, C3-C8 halocycloalkyl, C1 - C3 alkoxy, C1 - C3 halogenated dairy, C1 - C3 sulfur-burning, C1 - C3 halogen-burning sulfur, C1 - C3 burning sub-reading, Base, C1 - C3 haloalkylsulfinyl, C1 - C3 alkyl fluorenyl, C1 - C3 halosulfonyl, C1-C4 alkylamino, di-C1-C4 alkylamino, cyano, nitro Hydroxy 175 200836629 base, C1-C4 deciduous base, C1-C4 halogenated carbonyl group, Cl-C4 alkylcarbonyloxy group, fluorenyl group, C1-C4, several groups, Cl-C4 tooth substituent group. Burning her base, Cl-C4 Α 叛 叛 叛, Cl-C4 alkyl 蔷 蔷 oxy, C1 = halogenated oxy, aryl hydroxy, thiol or phenyl or more than one Substituent, a base represented by the general formula (2) (wherein, Yr Y2, Y3, Y4, Ys may be the same or different, and represent a nitrogen atom, a halogen atom, a C1-C6 alkyl group, a C1-C6 alkyl group, a halogen atom, a ci-C3 oxygenate. Base, C1 - C3 haloalkoxy, C1 - C3 sulphur group, C1 - C3 haloalkylthio group, ci: c3 sulphide fluorenyl group, Cl-C3 haloalkyl group, hydrazine group, Cl-C3 Base group, C1 - C3 halogenated basestone xanthene, ci - C4 amine group, two C1 - C4 amine group, cyano group, schiffyl group, per group, Cl - C4 group, C1 - C4 halogen burning charcoal Base, C1 - C4 succinyloxy, C1-C4 halogenated carbonyloxy, C1 - C4 aerobic acid group, ci-C4 halogenated oxygen group, C1 - C4 amine group, C1 - C4 halogen burning One or more substitutions of the same or different ones of the amine group, the ci-C4 alkyl ketone oxy group, the C1 - C4 haloalkyl sulfonyloxy group, the aryl sulfonyloxy group, the pentafluorosulfanyl group or the alkyl fluorenyl group Base, C1 - C6 ij alkyl, C2 - C4, C2 - C4, C2 - C4 alkynyl, C2 - C4 - alkynyl, C3 - C8 cycloalkyl, C3 - C8 - cycloalkyl, C1 -C6 alkoxy, C1 - C6 haloalkoxy, substituted C1 - C6 haloalkoxy: one or more substituents selected from the same or different ones selected from the group consisting of a hydrogen atom, a hydroxyl group, a chlorine atom, a bromine atom, an iodine atom, a C1-C6 alkoxy group or an α-C6 haloalkoxy group a C1-C6 haloalkyl group which may be substituted by one or more hydroxy groups, a C1-C6-substituted C1-C6-substituted alkyl group substituted by one or more C1-C6 haloalkyl groups, 176 200836629 C6 haloalkyl, can! One or more s alkoxy substituted C1 C1-C6 alkylthio, self-filament, Cl-C6 haloalkylthio, second-generation C1-C6 self-sintering sulfur: _ selected from hydrogen Atom, dance, know 2, iodine atom, C1-C6 alkoxy or C1-C6't atom, substituted with more than one substituent, the same in soil or Cl-C6 alkyl sulfhydryl , C1 — C6 haloalkyl sulfinyl group, 衫 ΐ : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : : Substituted by a oxy group or a C1—C6= one or more substituents which are the same or different, a fluorenyl group, a C—C6 aryl sulfonyl group, a C 1 —C 6 halogen group Sulfur Substituted by one or more substituents selected from the same or different nitrogen atoms, singular atoms, iodine atoms, a-C6 alkoxy groups or C1_C6 halogenated oxygens, a phase C1-C4 Alkoxycarbonyl, Cl-C4 S oxygen, C1 - C4 alkane C1-C4 haloalkyl, a C1 - C6 alkyloxy, hydrazine, C1 - C6 haloalkyl sulfonyloxy, C1 - C4 alkylcarbonyl, C1-C4 haloalkyl, C1-C4 alkoxycarbonyl, C1-C4 halocarbonyloxy, cyano, nitro, hydroxypentafluorosulfanyl, carboxyl, urethane, C1 C3 alkylaminocarbonyl, phenyl azo tomb, pyridinyloxy, soil substituted 17 octyloxy group · having a halogen atom, C1 - C4 alkyl group, ci~ C4 halogen group, substituted C1-C4 Alkyl, C2-C4 alkenyl, C2-C4 self-organol, C2-C4 alkynyl, C2-C4 alkynyl, C3_C8 cycloalkyl, C3-C8 cycloalkyl, Cl-C3 alkoxy, Cl- C3 haloalkoxy, C1-C3 alkane bowl, 'C1-C3 haloalkylthio, C1-C3 alkylsulfinyl, C1-C3 haloalkyl sulphate, Cl-C3 sulphur Sulfhydryl, C1 - C3 haloalkyl sulphate, ci-C4 alkylamine, 1 77 200836629 DiCl-C4 alkylamino, cyano, nitro, hydroxy, Cl-C4 alkylcarbonyl, ci-C4 halocarbonyl, Cl-C4 alkoxycarbonyl, Cl-C4 halocarbonyloxy, ci — C4 alkoxycarbonyl, C1-C4 haloalkyloxycarbonyl, C1-C4 alkylcarbonylamino, C1-C4 haloalkylcarbonylamine, C1-C4 alkyl anthraceneoxy, C1-C4 haloalkylsulfonyloxy a phenyl substituted phenyl group having the same or different substituents in the arylsulfonyloxy group, the arylsulfonyloxy group, the pentylsulfonyloxy group or the phenyl group: having a halogen atom, a C1 - C4 alkyl group, and a C1 group C4 _ alkyl, substituted Cl - C4 alkyl, C2 - C4, C2 - C4, C2 - C4 alkynyl, C2 - C4 haloalkynyl, C3 - C8 cycloalkyl, C3-C8 Halogenated alkyl group, C1-C3 alkoxy group, C1-C3 halogen alkoxy group, C1-C3 sulfur-burning group, ci-C3 halogen-burning sulfur group, C1-C3 alkylsulfinyl group, Cl-C3 halogen burning Kea sulphate, Cl-C3 sulphur base yellow broth, Cl - C3 halogen yellow base, Cl - C4 amine, di C1 - C4 alkylamine, cyano, nitro, hydroxy, C1 - C4 Alkylcarbonyl, C1~C4 halocarbonyl, Cl—C4 alkoxy , ci—C4 halocarbonyloxy, Cl—C4 azoxy, C1—C4 ce oxycarbonyl, C1-C4 alkylcarbonyl, C1-C4 haloalkyl, C1-C4 alkyl sulfonate One or more substituents which may be the same or different among the oxy group, C1-C4 haloalkylsulfonyloxy group, arylsulfonyloxy group, pentafluorosulfanyl group or phenyl group, heterocyclic group (herein heterocyclic group) Represents η than arginyl, decyl, N-oxygen, pyrimidinyl, fluorenyl, furyl, thienyl, oxazolyl, isoxazolyl, oxadiazolyl, thiazolyl, isothiazolyl, thia Diazolyl, pyrrolyl, imidazolyl, triazolyl, pyrazolyl, tetrazolyl, benzothiazolyl, benzoxazolyl, benzofuranyl, thiophenyl, quinolinyl, isoquinoline Base, fluorenyl, isodecyl, 1 Η-isoindenyl, 2 3^dihydro-benzo[Μ]diyl, benzoquinone, 3]di(tetra)yl, tetrahydro*sodium or diterpene a cyclyl group, or a substituted heterocyclic group having a halogen atom, a-C4 alkyl group, Cl-C4, a silk, a substituted Cl-C4 alkyl group, a C2-C4 alkenyl group, a C2-C4- group, 2-C4 alkynyl group, C2 - C4 tooth block base, C3_C8 ring wire, c3_c8 tooth Alkane, C1-C3 alkoxy, C1-C3# alkoxy, C1-C3 alkylthio, ci~ ΰ 瓜 Cl Cl Cl C3 alkyl sulphate, ci-C3 halogenated sulphate, 178 200836629 Cl-C3 fluorenyl fluorenyl, C1_C3 haloalkyl fluorenyl, C1 - C4 alkylamino, di-C4 amine, cyano, nitro, thiol, Cl-C4, C1 - C4 ^ a few groups, a C1-C4 alkylcarbonyloxy group, a C1-C4 i-alkylcarbonyloxy group, a C1-C4 alkoxymethyl group, a C1-C4 haloalkyloxycarbonyl group, a C1-to-alkyl alcoholyl group, a ci-C4 tooth An alkylamine-based group, a C1-C4 alkyl sulfonylxanthine group, a C1-C4-alkylsulfonyloxy group, an arylsulfonyloxy group, a pentafluorosulfide group or a phenyl group, the same or different one or more Substituent (heterocyclic group here means hydrazine, η ratio bite group, N- ruthenium group, mouth bite group, tower cultivating base, fluorenyl group, σ thiophene group, fluorenyl group, 嗤 、 , η, 峻, 嗟嗤, 异, 嗟, 吼, 吼, 嗤, 嗤, 嗤, 嗤, 嗤, benzothiazolyl, Benzooxazolyl, benzofuranyl, benzothienyl, quinoline Base, isoquinolinyl, fluorenyl, isodecyl, 1Η-isoindolyl, 2,3-dihydro-benzo[I,4]dijin, benzo[丨,3;^噚Azolyl, tetrahydropyranyl or dihydropyranyl-only 、:, Ys may be the same or different and represent a halogen atom, a Ci-C4 alkyl group, a Cl-C4 haloalkyl group, a C1-C3 sulfur-burning group, C1-C3 halogenated base, C1-C3 alkylsulfinyl, C1-C3-alkylsulfinyl, C1-C3 alkylsulfonyl, C1-C3 haloalkylsulfonyl or cyano In the case where γ3 is not represented by C2_C6 perfluoroalkyl, C1-C6 perfluoroalkylthio, C1-C6 perfluoroalkylsulfinyl or C1-C6 perfluoroalkylsulfonyl), or The base represented by the general formula (3) (wherein Y6, Y7, Ys, γ9 may be the same or different and represent a hydrogen atom, a halogen atom, a C1-C6 alkyl group, a C1_C6 haloalkyl group, a C2_C4 alkenyl group, a C2-C4 haloalkenyl group, a C2-C4 alkyne , C2_C4 _ alkynyl, (^-(3)cycloalkyl, C3-C8 halocycloalkyl, C1-C4 alkoxy, ci-C4 haloalkoxy, C1-C6 halo which may be substituted by more than one hydroxy group a mercapto group, a cl-C6 haloalkyl group which may be substituted by one or more alkoxy groups, a C1-haloalkyl group which may be substituted by one or more haloalkoxy groups, a C1-C6 alkylthio group, a C1-C6 halogen Alkylthio, C1 - C6 alkyl sulfinylene, C1 - C6 haloalkyl 179 200836629 stellite, Cl-C6 alkylsulfonyl, Cl~C6 haloalkylsulfonyl, C1_C6 Xantheneoxy, Cl—C6 halogenated fluorenylxanthine, C1-C4 calcined carbonyl, Cl-C4 haloalkylcarbonyl, C1-C4 alkoxycarbonyl, ci~C4 halocarbonyloxy, cyano, nitrate Base, hydroxy, pentafluorosulfanyl, phenyl, substituted phenyl·· having a halogen atom, a C1-C4 alkyl group, a C1-C4i alkyl group, a substituted Cl-C4 alkyl group, a C2-C4 group Alkenyl, C2-C4 haloalkenyl, C2-C4 alkynyl C2-C4 haloalkynyl, C3~C8 cycloalkyl, C3-C8 halocycloalkyl, 〇-〇3 alkoxy, €:1 to €3 haloalkoxy, (::1_(:3 alkane sulphur) Base, (:: 1-C3 haloalkylthio, C1 - C3 alkylsulfinyl, C1 - C3 haloalkylsulfinyl, Cl - C3 alkylsulfonyl, C1 - C3 haloalkyl Sulfhydryl, C1_C4 alkylamino, di-C1-C4 alkylamino, cyano, nitro, hydroxy, C1__C4 alkylcarbonyl, C1_C4 aryl group, Cl-C4 carbonyloxy, Cl-C4 halocarbonyloxy , Cl—C4 alkoxycarbonyl, Cl—C 4 haloalkoxycarbonyl, C 1 -C 4 alkylcarbonylamino, C 1 -C 4 i alkylcarbonyl, benzyl, Clj~C 4 alkylsulfonyloxy, C 1 -C 4 _alkyl Continuing the same or different one or more substituents in the decyloxy, arylsulfonyloxy, pentafluorosulfanyl or phenyl group, a heterocyclic group (the heterocyclic group here means pyridyl, σ-pyridyl) , N-oxaridinyl, pyrimidinyl, hydrazine, furyl, thienyl, oxazolyl, isoxazolyl, oxadiazolyl, thiazolyl, isothiazolyl, thiadiazolyl, pyrrolyl, Imidazolyl, triazolyl, pyrazolyl, tetrazolyl, benzothiazolyl, benzo Azolyl, benzofuranyl, J-thienyl, quinolyl, isoquinolyl, decyl, isodecyl, 1H-isodecyl, 2,3-dihydro-benzo[1, 4] a diterpene group, a benzophenanyl group, a 3]dicarbazolyl group, a tetrahydropyranyl group or a dihydropiperidyl group, a ^ or a substituted heterocyclic group: having a halogen atom, a C1 - C4 alkyl group, C1 - C4 haloalkyl, substituted C1-C4 alkyl, C2-C4 alkenyl, C2_C4 haloalkenyl, C2-C4 alkynyl, C2-C4 i-alkynyl, C3-C8 cycloalkyl, C3 - C8 Halogenated alkyl, Cl—C3 alkoxy, Ci—C3 alkylalkoxy, C1-C3 alkylthio, α—C3 halogenated sulfur, ci—C3 alkylsulfinyl, ci-C3 halogen A sulfinyl group, a C1-C3 alkyl decyl group, a C1 - C3 haloalkyl fluorenyl group, a C1_C4 alkylamino group, a sig. 180 200836629 Cl-C4 alkylamino group, a cyano group, a nitro group, a hydroxyl group, a C1_C4 alkylcarbonyl group, Ci — c4 haloalkylcarbonyl, Cl—C4 carbonyloxy, C1-C4 halocarbonyloxy, C1-C4 alkoxy, C1-C4 i-oxygen, C1_C4 hydrazino, C1_C4 halane Base, C1: C4 basestone xanthine, C1-C4 self-combustible The same or different one or more substituents in the methoxy group, the aryl stone oxydipentafluorosulfanyl group or the phenyl group (the heterocyclic group here means pyridyl group, pyridyl group, N-oxidized pyridyl group) , pyrimidinyl, fluorenyl, cumyl. Terpeptidyl, fine base, heterosexyl group, "f bismuth group, surface group, ^ 唉, 基, 嗟 嗤 、, 财 基, 咪 钱, 三哇基, 対基, 四嗤二基, 苯(四) Money, benzoheptyl, benzene (tetra) phenyl, benzyl, bis: iso-phenoyl, 1H-iso-yl, Μ-dihydro-benzo: 弁i1,3] bis, tetrahydro pi Is a homo group or a dihydro bridging group), and the same, or different, and represents a halogen atom, a C1 - C4 alkane C 4 haloalkyl group, a C1 - C3 alkylthio group, a C1_C3 halogenated C3 alkane A sulfinyl group, a C1-C3 dentate, a halogenated alkaloid, a C1 - ... ® alkyl hydrazino group, a C1-C3 alkyl sulfonyl group, a hydrazine group or a gas group, which is not included in the C1-C4 A plant species or a compound of the genus of the genus of the genus of the genus of the genus of the genus of the genus of the genus of the genus of the genus of the genus In the formula, it is a carbon atom: a nitrogen atom or an oxidized nitrogen atom; 2 A3, A4 represents a carbon atom; &gt;, I independently of each other represents a hydrogen atom or an alkoxy atom or a sulfur atom Jitf: Atom, coffee or tri-fiber Qi means phenyl, alkyl-U if-m C1-C4 alkyl, C1-C4 halogen C2-C4 alkynyl, C2-C4; alkenyl, C2-C4 alkenyl, alkynyl, C3~C8 cycloalkyl, C3_C8 halocycloalkane 181 200836629 Base, Cl~C3 alkoxy, C1-C3 haloalkoxy, Cl-C3 alkylthio, C1~C3 functional thiol, ci-C3 alkylsulfinyl, ci-C3 haloalkyl sulfin Sulfhydryl, C1 - C3 alkylsulfonyl, C1 - C3 halogenated fluorenylxanthyl, C1 - C4 arunyl, di C1 - C4 alkylamino, cyano, nitro, hydroxy, C1 - C4 alkylcarbonyl, a ~C4 carbonyl, Cl-C4 alkylcarbonyloxy, C1-C4 halocarbonyloxy, Cl-C4 alkoxy, C1-C4 halooxycarbonyl, C1-C4 alkanoamine, C1-C4 One of the same or different ones of the i-alkylene group, the C1-C4 alkylsulfonyloxy group, the C1-C4 haloalkylsulfonyloxy group, the arylsulfonyloxy group, the pentafluorosulfanyl group or the phenyl group. The above substituent, heterocyclic group (herein, heterocyclic group means 咐^, base group, oxidized η ratio I? group, 'pyridine group, hydrazine base, furyl group, thienyl group, carbazolyl group, different Carbazolyl, hydrazine, sigma, sigma, sulphate, bismuth , imidaz, trisal, pyrazolyl, tetrazolyl, 2,3-dihydro-benzo[1,4]dioxin, benzo[cutinyl, tetrahydropyranyl Or dihydropiperidyl), or a substituted heterocyclic group: having a halogen atom, a C1-C4 alkyl group, a C1-C4 haloalkyl group, a substituted C1-C4 alkyl group, a C2-C4 alkenyl group, C2-C4 haloalkenyl, C2-C4 alkynyl, C2-C4 haloalkynyl, C3-C8 cycloalkyl, C3-C8 halocycloalkyl, Cl-C3 alkoxy, C1-C3 haloalkoxy, C1 - C3 alkylthio, C1 - C3 haloalkylthio, C1 - C3 alkylsulfinyl, C1 - C173 haloalkylsulfinyl, C1 - C3 alkylsulfonyl, C1 - C3 halo Sulfosyl group, Cl-C4 alkylamino group, di-, C1-C4 alkylamino group, cyano group, nitro group, hydroxyl group, Cl-C4 alkylcarbonyl group, C1-C4 tooth-burning k-group, C1-C4 green-green base , C1 - C4 halogen decyloxy, C1 - C4 oxycarbonyl, Cl - C4 halooxycarbonyl, Cl - C4 alkylcarbonyl, Cl - C4 halocarbonyl, Cl - C4 alkyl sulfonate One or the same of Cl, C4 haloalkylsulfonyloxy, arylsulfonyloxy, pentafluorosulfanyl or phenyl The above substituents (herein, heterocyclic group means 吼17 well group, σ ratio 11 base group, N-oxidation 0 to 0 base group, continued 11 base group, tower 17 well group, furyl group, thienyl group, carbazolyl group, isoindole Azyl, oxadiazolyl, thiazolyl, isothiazolidinyl, indenyl, fluorenyl, miso, triterpene, fluorenyl, tetradecyl, 2,3-dihydro-benzo [1,4]dimercapto, benzo[1,3]dioxazolyl, tetrahydropyranyl 182 (2) (2) 200836629 or dihydrogenyl), Q2 is of formula (2) (wherein, YrY5 may be the same or different, and represents a halogen atom, Cl, C6^C1-C6 haloalkyl, Cl-C6 alkoxy, Cl-C6 haloalkoxy, Cl, = marry sulfur ^, C1 - C6 haloalkylthio, Ci-C6 alkylsulfinyl, C1~C6 ^ sulphate, C1-C6 alkylsulfonyl, Cl-C6 haloalkylsulfonyl, nitro; fl Y1, Y2, Y4 may be the same or different, and represent a hydrogen atom, a halogen atom or a group, i-Ys represents a trifluoromethyl group, a C1-C6 perfluoroalkoxy group, a pentafluorosulfanyl group, and a C1 group. C6 haloalkoxy: substituted by a substituent selected from the group consisting of a hydrogen atom, a hydroxyl group, a halogen atom, a bromine atom, an iodine atom, a C1-C6 alkoxy group or a C1-C6 haloalkoxy group, % with or without a C1-C6 haloalkylthio group: selected from a hydrogen atom, a hydroxyl group, a chlorine atom, a desert atom, an iodine atom, a Cl-C6 alkoxy group or a C1-C6 haloalkoxy group. Substituted by one or more substituents, polysubstituted C1 - C6 haloalkyl sulfinyl group · selected from a hydrogen atom, a hydroxyl group, a chlorine atom, a bromine atom, an iodine atom, a C1_C6 alkoxy group or a Cl-C6 halogen Alkane Intermediate phase: substituted with one or more substituents of the same or different, or substituted C1 - C6 - calcyl sulphate: selected from a hydrogen atom, a trans group, a chlorine atom, a bromine atom, an iodine atom, a C1_C6 alkoxy group A compound substituted with one or more substituents of the same 4C1-C6 haloalkoxy group. i If you apply for the special machine for the first time, the seed work harvest _ insecticidal domain, Fu Ning, the compound represented by the pass ^ (i), in the formula (]), 4 represents the carbon source J, hydrogen atom or The oxidized nitrogen atoms a2, a3, and a4 represent carbon atoms; independently of each other, represent a hydrogen atom S%C1-C4 alkyl; 183 200836629 Gi, G2 independently represent an oxygen atom or a sulfur atom; XJ is the same or different and represents a hydrogen atom, a 素 atom or a triple η represents an integer from 〇 to 4; 'Q represents a phenyl group, a substituted phenyl group: having a halogen atom, a C1 - C4 alkyl group, a C1_C4 halogen group, a substituted C1 - C4 alkyl group, C2-C4 alkenyl, C2-C4 functional, 2-C4 alkynyl, C2-C4 haloalkynyl, C3-C8 cycloalkyl, C3_C8 halocycloalkyl, C1-C3 alkoxy, C1-C3 Alkoxy, Cl - C3 alkylthio, C1_C3 halogenated sulfur, ci-C3 alkylsulfinyl, ci-C3 i alkylsulfinyl, Cl C3 alkylsulfonyl, ci-* C3 _ sulphonylsulfonyl, C1 - C4 acrylamine, diCl-C4 alkylamino, cyano, nitro, thiol, C1 - C4 alkylcarbonyl, C1 - C4 _ carbonyl, Cl - C4 alkyl carbonyl Oxygen, C1 - C4 Alkylcarbonyloxy, C1-C4 alkoxyoxy, C1-C4 haloalkyloxy, C1-C4 alkanoamine, C1-C4 haloalkylamino, C1-C4 alkyl decyloxy, C1 a one or more substituents which may be the same or different among C4 haloalkylsulfonyloxy, arylsulfonyloxy, pentafluorosulfanyl or phenyl, heterocyclic group (herein, heterocyclic group means hydrazine , 11 than bite base, N-oxidized u than bite base, 'bite base, tower tillage base, 吱 基 base, 吩 基 base, tr tr sit base, 嗤 嗤 base, 噚 也 base, thiazolyl, different Thiazolyl, thiadiazolyl, pyrrolyl, imidazolyl, triazolyl, oxazolyl, tetrazolyl, 2,3-dihydro-benzo[1,4]dioxin, benzo[a] Diterpenoid olfactir, tetrahydro XI base or dioxime oxime), or substituted heterocyclic group: having a halogen atom, a ci-c4 alkyl group, a C1-C4 haloalkyl group, a substituted C1 group —C4 alkyl, C2-C4 alkenyl, C2-C4 haloalkenyl, C2-C4 alkynyl, C2-C4-block, C3-C8 cycloalkyl, C3-C8 haloalkyl, Cl-C3 Oxy, Cl—C3 halooxy, C1-C3 sulphur, ci-c3 haloalkylthio, Cl—C3 alkyl Sulfonyl, Cl-C3 haloalkylsulfinyl, C1 - C3 alkylsulfonyl, C1 - C3 haloalkylsulfonyl, Cl - C4 alkylamine, diCl - C4 amine, cyanide Base, exact group, mercapto group, C1-C4 calcined|carbon-based, ci-C4 haloalkylcarbonyl, C1-C4 alkoxycarbonyl, C1-C4 halocarbonyloxy, C1-C4 alkoxy&amp; base, Cl —C4 halogenated oxygen group, C1—C4 serocarbonylamine group, Cl—C4 halogenated amine 184 200836629 ^, C1; C4 recorded sulfonic acid oxy group, C1_C4 haloxime oxime, aryl stone preparation oxygen ^ Production = thiophenyl towel _ or more than one substituent (in this case, Shenjing, base, N-oxidation _ base, base, base, = base thiophene, keji, Different, base, $ two money, base Junji, ^ two Junji, turn base, ♦ sit-base, three-salt base, coffee base, four base: fr plant chlorine-benzo[1,4] two current well base , benzo[u]octa-based, tetrahydro-d-denyl or dihydro- 13-meryl), Q2 is of general formula (2) 丫4 (wherein 'Y is not C1-C4 burned carbonyl, C1-C4-alkylcarbonyl, C1-C4 alkylcarbonyloxy, C1-C4 alkoxy, Cl-C4 alkoxycarbonyl, C1-C4 tooth burned Oxycarbonyl, C1-C4 alkylamino, C1-C4 haloalkylcarbonyl, C1_C4 alkylsulfonic acid, C1-C4 halogenated fluorenyloxy, or substituted Cl-C4 alkyl: selected a halogen atom, a C1_C3 alkoxy group, a C1-C3 halogen alkoxy group, a C1-C3 sulfur-burning group, a ci-C3 ii sulfur-burning group, a C1-C3 group Alkylsulfinyl, C1 - C3 haloalkyl, ci - C3 alkyl, C1 - C3 haloalkyl fluorenyl, C1 - C4 alkylamino, dici-C4 alkylamino, Cyano, nitro, hydroxy, C1-C4 alkylcarbonyl, C1-C4 functional carbonyl, Cl-C4 alkoxycarbonyl, C1-C4 halocarbonyloxy, C1-C4 alkoxycarbonyl, C1-C4 halane Oxycarbonyl, C1-C4 alkylcarbonylamino, C1-C4 haloalkylcarbonyl, ci-C4 alkylsulfonyloxy, C1-C4 haloalkyl read decyloxy, arylsulfonyloxy, pentafluorosulfur Substituted by one or more substituents of the same or different alkyl or alkyl decyl groups, Y5 represents an i atom, a C1-6 alkyl group, a C1 - C6 i alkyl group, a C1 - C6 alkoxy group, a C1 - C6 group Haloalkoxy, C1 - C6 thiol, Cl - C6 - alkylthio, C1 - C6 alkyl sulfinyl, C1 - C6 haloalkyl sulfinyl, ci_C6 alkyl ruthenium, C1 - C6 Alkyl sulfonic acid group, cyano group or nitro group, Y2, A may be the same or different, and represent a hydrogen atom, a halogen atom, a C1-C6 alkyl group; 185 200836629 A furnace, a methoxy group, a C2-C6 perfluoroalkyl group , μ-Guangji, C1-C6 perfluoromethane _ base, α, Wang milk difluoromethyl, C1-C6 perfluoroalkoxy, sulphur-burning base, Wang thief base yellow exposure, substitution C1_C6 _halogen alkoxy: selected from chlorine atom, recorded π ], a halogen atom, a C1-C6 alkoxy group or a C1-C6 halogenated alkoxy group, wherein f ^ ί is substituted with one or more substituents, and the same or unsubstituted Cl—C6 self-sintering sulfur group: Substituted by more than one substituent of the atom of the chloroform;; atom, C1, oxy or C1_C6 fluorene, phase 冋 or not = C1-C6 亚 亚 醯 醯 : :: selected from hydrogen source, The C1, oxy or Cl = oxime is substituted with the same or different substituents, or the α is the equivalent of the C6 dentate hetero group: selected from the nitrogen atom, the base A compound of a gas atom, a subunit, an α-C oxy group or a C1_C6 ή = substituent substituted by one or more substituents. τ is the same or ί申 ίίΐ ΐΐ ΐΐ 种 种 种 种 种 种 种 种 种 种 种 种 种 种 ΐΐ ΐΐ ΐΐ ΐΐ ΐΐ ΐΐ ΐΐ ΐΐ ΐΐ ΐΐ ΐΐ ΐΐ ΐΐ ΐΐ ΐΐ ΐΐ ΐΐ ΐΐ ΐΐ ΐΐ ΐΐ ΐΐ ΐΐ ΐΐ ΐΐ ΐΐ ΐΐ ΐΐ ΐΐ ΐΐ Oxidized nitrogen atom; 2, a3, a4 represent a carbon atom; R1, R2 independently of each other represent a hydrogen atom or C1_C4 λ·Gl, &amp; independently represent an oxygen atom or a sulfur atom; = is, the same or different, represents a hydrogen atom The halogen η is not represented by an integer of 4; soil, Qi represents a phenyl group, a thiol group, and a fluorenyl group: a C1-C4 alkyl group selected from a _ s atom, a C4 alkyl group, a-C4 dentate II, C2 ~C4 ~ C4 alkynyl, C2 - C4 i alkyne, A silk (tetra), C2 haloalkynyl C3 - C8 cycloalkyl, C3-C8 halocycloalkyl, two? , base, C1—c3, sulphur-based, d-C3, sulfur-based, a-C3 4 melon, C1-C3, sub-branched, sulphur, C1f 186 200836629 C3, C1—C3 _ 基 continuation base, Cl - C4 amine group, diCl: C4 amine group, cyano H hydroxyl, Cl-C4 test, C1-C4 halogen burnt base, C1-C4 decyloxy, C1 -C4 dentate, alkoxy, C1-C4 alkoxycarbyl, C1 - C4 haloalkoxycarbonyl, Cl - C4 alkylcarbonylamino, C1 - C4 haloalkylcarbonyl, • C1: C4 alkyl sulphate Substituted by the same or different substituents of the C1-C4 haloalkylsulfonyloxy group, the arylsulfonyloxy group, the pentafluorosulfonyl group or the phenyl group, a heterocyclic group (herein Cycloalkyl represents pyridyl, acridinyl, N-oxatoninyl, pyrimidinyl, fluorenyl, furyl, thienyl, oxazolyl, isoxazolyl, oxadiazolyl, thiazolyl, isothiazole Base, thiadiazolyl, pyrrolyl, imidazolyl, triazolyl, •, pyrazolyl, tetrazolyl, 2,3, di-di-n-benzo[1,4]dioxinyl, benzo[1] , 3] biscarbazolyl, tetrahydropyranyl or dihydropiperidyl), or substituted heterocyclic: selected from Halogen atom, Cl - C4 alkyl group, Cl - C4 haloalkyl group, substituted Cl - C4 alkyl group, C2 - C4 alkenyl group, C2 - C4 haloalkenyl group, C2 - C4 alkynyl group, C2 - C4 haloalkynyl group , C3 - C8 cycloalkyl, C3 - C8 halocycloalkyl, C1 - C3 alkoxy, C1 - C3 haloalkoxy, C1-C3 alkylthio, C1 - C3 halogen thiol, Cl - C3 A sulfinyl group, a C1 - C3 halogenated carbazide group, a C1 - C3 alkylsulfonyl group, a C1 - C3 haloalkylsulfonyl group, a Cl - C4 acryl group, a di C1 - C4 amine group, Cyano, stone succinyl, thiol, (^1 - 〇4, carbonyl, (^1 - 〇4, halogen, carbonyl, C1 - C4, thiol, Cl - C4, oxy-oxyl, ci - C4, oxy- Base, C1-C4 halogen-burning oxygen base, Cl-C4 burning amine, ci-C4 halogen-burning Wei-amine, C1-C4 alkylsulfonyloxy, C1-C4 halogen-based hydrazine, aromatic Substituted with one or more substituents of the same or different sulfonyloxy group, pentafluorosulfoxy group or phenyl group (herein, heterocyclic group means pyridinyl group, pyridyl group, N-oxidized pyridyl group, pyrimidinyl group, Sulfhydryl, furyl, thienyl, oxazolyl, isoxazolyl, anthracene Diazolyl, oxime, isothiazolyl, thiadiazolyl, pyrrolyl, imidazolyl, triazolyl, pyrazolyl, tetrazolyl, 2,3-dihydro-benzo[1,4]噚Plough, benzo[1,3]dioxazolyl, tetrahydronenyl or dihydropyranyl), Q2 is of general formula (2) 187 (2) (2) 200836629 (C, ^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^^ Buy fluorenyl or Cl-C6 haloalkylsulfonyl; alkoxy 5, Hct^;::H6 alkyl, C1-C6 (tetra), C1-C6 C1 - C6pi haloalkoxy, C1-C6 alkane , C1-C6 haloalkylthio, 醯A, Cf of fulvic acid, C1-C6^alkyl sulphate, C1-C6 alkyl sulphate C6-alkyl, cyano or succinyl; 2; I may be the same or different, meaning a hydrogen atom, a self-priming atom, C1 - C6 Y3 represents a halogen atom). Lizhong Shen 1st plant draft or harvest _ reduced composition, /, formazan (1) The compound represented by the formula '1', Αι denotes a rabbit atom, a nitrogen atom or an oxidized nitrogen atom; A2, A3, A4 represent a carbon atom; 'Rl, ruler 2 independently of each other represents a hydrogen atom or C1 —C4 alkyl; Gi,〇2 are independent of each other and represent an oxygen atom or a sulfur atom. The same or different, meaning a hydrogen atom, a halogen atom or a tri-gas methyl group; η represents an integer from 〇 to 4; Qi represents a phenyl group, * ΐίΐ group :Selected from halogen Atom, C1-C4 alkyl, C1-C4 halogen H, α-=alkyl, C2-C4 alkenyl, C2-C4 squara, C2 &amp; base, ctc8 cyclofilament, gw haloalkyl, ^ A haloalkoxy group, C1-C3 alkylthio group, Cl-C3 haloindole-based group, C1-C3 haloalkyl group, C1-C3 alkyl fluorenyl group, .Cl-C3 i-based carboxylic acid Base, C1-C4 amine group, two C1 ^ Xiaoji, weave, C1-C4 silk base, Cl-C4 halogen burnt base, a-C4 burnt base, C1_C4 self-burning oxy, C1-c Alkyl, 200836629 Cl-C4 haloalkoxycarbonyl, C1-C4 alkylcarbonylamino, C1-C4 haloalkylcarbonyl, Cl-C4 alkylsulfonyloxy, C1-C4 haloalkylsulfonyloxy, One or more substituents which may be the same or different among the arylsulfonyloxy group, the pentafluorosulfanyl group or the phenyl group; a heterocyclic group (herein a heterocyclic group represents a pyridyl group, a pyridyl group, an N-phosphonium oxide; Base, °岔, bite base, tower well base, bite σ south base, porphyrin base, u-deficiency base, isosaki σ siting base, χτ number- piji, sulfhydryl group, heteroruthenyl group, π plug Ditr, sulfhydryl, imidaz, trisal, &quot;bisazolyl, tetrazolyl, 2,3~dihydro-benzo[1,4]dioxene a benzo[,3]dioxazolyl, tetrahydropyranyl or dihydropentanyl group, or a substituted heterocyclic group: selected from a halogen atom, a C1 - C4 alkyl group, a C1 - C4 _ Alkyl, substituted C1-C4 alkyl, C2-C4 alkenyl, C2-C4 alkenyl, C2-C4 alkynyl, C2-C4 cryptyl, C3 - C8 cycloalkyl, C3 - C8 halo ring Burning base, C1 - C3 alkoxy group, C1 - C3 i grafting oxygen group, C1-C3 sulfur-burning group, C1~ C3 S alkylthio, C1 - C3 alkyl sulfinylene, C1 - C3 i alkyl sulfinyl, C1 - C3 alkyl sulfonyl, Cl ~ C3 haloalkyl fluorenyl, Cl - C4 alkylamino , diCl—C4 amine group, cyano group, nitro group, hydroxyl group, C1-C4 alkyl group, C1-C4 halogen-burning carbonyl group, C1-C4 alkylcarbonyloxy group, C1-C4 haloalkylcarbonyloxy group, C1— C4 alkoxy group, C1 - C4 halogenated oxycarbonyl, Cl - C4 alkylcarbonyl group, C1 - C4 halogenated carbonyl amine group, C1; C4 alkyl group, fluorenyl group, Cl-C4 haloalkyl group The same or different among the arylsulfonyloxy group, the pentafluoroanthracene group or the phenyl group, wherein the heterocyclic ring of the i or more substituents is 1 group, the money, the N-oxidation read group, the front group, Tower spray, ° gram base, sputum base, slogan sulphate, plague k ̄ ^ glycerazole, dish-oxazolyl, pyridyl, oxazolyl, oxadiazolyl, thiazolyl, isothiat 2 3 ί, taste, sputum, three shop, saliva, four. Sit-base, or Ernan base well, benzo[ι,3] di-s-sitting, tetrahydro(tetra)-based Q2 is of general formula (4) Y4 Rc 189 200836629 (wherein Yi and Ys may be the same or different and represent a halogen atom, a C1-C6 alkyl group, a ci-C6 ft alkyl group, a C1-C6 alkoxy group, a C1-C6-alkoxy group, ^-(3)alkylthio^:C1~C6 ialkylthio, C1-C6 alkylsulfinyl, C1 - C6 ialkyl sub-1&amp; base, C1-C6 alkylsulfonyl, C1 - C6 The base stone, cyano group, nitro group; / alkyl hydrazine 2, 1 may be the same or different, representing a hydrogen atom, a halogen atom, C1 - C6; Ra represents an i atom or a hydroxyl group; Rc each independently represents a hydrogen atom, a base, a halogen atom or a ci-C6 halide, wherein the one having more than one hydrogen atom, a silk atom, a chlorine atom, a plant species for use in the application of the 81st item of the invention, and a pesticidal composition; At least one of Ri and R2 is ci-c4 alkyl. · A pesticidal composition for plant seeds or harvests, (X)n^^ g2 in one or two of T: = with = (5), R, i where 'Al, A2, A3, ~ each represents a carbon atom, a nitrogen atom or a vaporized nitrogen" Z represents — or —n(Ri)qi; G2 ^ ^C1-C4 C1 ^C4 ^ Three gas meter _ child 'cafe, 1C3 appearance woman n represents an integer from 0 to 4; Qi represents a phenyl group, a substituted phenyl group: a C1-C4 group selected from a halogen-based group, a C1-C4 group, and a C~C4 group. Cl C4 says, C2 - C4, c: C4, halo, C2 190 200836629 a 4^: C3.-C8^^C3-c8 i w. C1-C3 alkanoyl, C1-C3 i Alkoxy group, C1 - C3 burnt stone Liumei ϋ 3 silk Ark base, C b c3 halogen wire = training base, C3 alkyl % shout, C1 - C3 sharp base pyruvate group, C1 - C4 amine burning beauty, two - C4 ^ ^ , . ^ . C1^C4 ^ Cllc4&quot;*^ t C4~^^ α—2 I-silyl, C1-C4(tetra)-amine, C1; C4 stellite*milk, C1-C4 from filament Alkyl, tetrahydronaphthyl, C3 - C8 ring-burning base, a 虱P soil 苐 base, 9-side rolling base, adamantyl or deducting group), substituted carbocyclic group: selected from halogen atom, C1_C4 wire, a_c, base, Substituted C1-C4 alkyl, C2-C4 alkenyl, C2-C4-yl, ,, Wu-^-yl, C8 cyclofilament, C8-ring alkyl, C1 —C3 alkyl fluorenyl, C1_C3 haloalkoxy, C1_C3 alkylthio, ci~ C3 halogen thiol, C1-C3 phenyl sulfhydryl, C1_C3 aryl sulfhydryl, ci-C3 alkyl ruthenium , C1-C3 haloalkyl fluorenyl, C1-C4 alkylamino, diCl C4 aminino, cyano, nitro, thiol, ci-C4 alkyl, ci-C4, alkoxy, Cl-C4 alkylcarbonyloxy, ci-C4 halocarbonyloxy, C1-C4 alkoxycarbonyl, C1-C4 halooxycarbonyl, C1-C4 alkylcarbonyl, C1_C4 halocarbonylcarbonyl, C1: a C4 alkylsulfonyloxy group, a C1-C4 haloalkylsulfonyloxy group, an arylsulfonyloxy group, a pentafluorosulfoxy group or a phenyl group having the same or different one or more substituents (carbon ring here) The group represents a naphthyl group, a tetrahydronaphthyl group, a C3-C8 cycloalkyl group, a dihydroindenyl group, a hexyl group, a 9-side oxy group, an adamantyl group or a hypocotyl group, and a heterocyclic group (herein Ring group means well group, bismuth ratio σ group, N-phosphonium hydrazide group, pyrimidinyl group, hydrazine group, furyl group, thienyl group, carbazolyl group, isoxazolyl group, oxadiazolyl group , isoindolyl, indenyl, fluorenyl, miso, triterpenoid Base, % oxazolyl, tetrazolyl, benzothiazolyl, benzoxazolyl, benzofuranyl, benzothienyl, quinolyl, isoquinolyl, indolyl, isodecyl, 1Η Isomeric thiol, 191 200836629 2,3 - dihydro-benzo[1,4]dijin, benzo[1,3]dioxazolyl, tetrahydropyranyl or dihydropyranyl) Or substituted heterocyclic group: selected from a halogen atom, a C1 - C4 alkyl group, a C1 - C4 halogen alkyl group, a substituted Cl-C4 alkyl group, a C2 - C4 alkenyl group, a C2 - 4 4 i alkenyl group • C2-C4 alkynyl, C2-C4 haloalkynyl, C3-C8 cycloalkyl, C3-C8 halocycloalkyl, C1-alkoxy, C1-C3 halo alkoxy, C1-C3 sulphur , C1 — C3 halogenated sulfur base, Cl—'C3 alkyl sulphate yellow base, C1-C3 halogenated sulphate yellow base, C1-C3 alkyl sulfonyl group, C1—C3 i alkyl sulfonate Base, Cl—C4 alkylamino group, di C1—C4 alkylamino group, cyano group, nitro group, hydroxyl group, ci—C4 alkylcarbonyl group, C1-C4 • halogenated carbonyl group, C1—C4 alkylcarbonyloxy group, C1—C4 Haloalkylcarbonyloxy, C1 -C4 alkoxyoxy, C1 -C4 haloalkoxycarbonyl, C1-C4 alkanoylamino, C1 -C4 halo One of the same or different ones of a carbonylamino group, a C1-C4 alkylsulfonyloxy group, a C1-C4 haloalkylsulfonyloxy group, an arylsulfonyloxy group, a pentafluorosulfanyl group, an amine group or a phenyl group. The above substituents (herein, heterocyclic group means pyridyl, pyridyl, anthracenyl fluorenyl, pyrimidinyl, taudecyl, furyl, thienyl, oxazolyl, isoxazolyl, oxadiazole Base, thiazolyl, isodecyl, oxime, η, η, η, 三, 三, σ, 嗤, tetradecyl, benzothiazolyl, benzoxazolyl, Benzopyranyl, benzothienyl, quinoline isoquinolyl, fluorenyl, isodecyl, m-isoindenyl, 2,3-dihydro- _ ^ and [1,4]噚 基, 笨 并 [ι, 3] carbazolyl, tetrahydropyranyl or dihydropiperidyl); Q2 is phenyl, substituted phenyl · selected from halogen atom, C1 - C4 alkane , C1 - C4, substituted C1 - C4 alkyl, C2 - C4 alkenyl, C2 - C4 alkenyl, g - C4 alkynyl, C2_C4 haloalkynyl, C3 - C8 cycloalkyl, C3_C8 halo ring Alkyl, C1 - C3 alkoxy, C1-C3 haloalkoxy, C1-C3 sulfur-sulphur, a — sulphur-based, Cl-C3 alkylsulfinic acid group, Cl-C3 haloalkyl sulfonate, C3 alkylsulfonyl, C1-C3 alkyl sulfonyl, C1-C4 alkylamine Di^=4 an amine group, a cyano group, a nitro group, a thiol group, a C1 - C4 alkyl group, a C1 = C4—J group, a C—C 4 alkylcarbonyloxy group, a C 1 —C 4 alkanecarbonyloxy group, a hydrazine 1 Alkoxycarbonyl 192 200836629 C1 — C4 haloalkoxycarbonyl, C1-C4 alkylcarbonylamine, Cl-C4 haloalkylcarbonyl, C1-C4 alkylsulfonyloxy, C1-C4 halogenated fluorescene One or more substituents or carbocyclic groups which are the same or different among the oxy group, the arsenylxanthyloxy group, the pentafluorosulfoxy group or the phenyl group (wherein the carbocyclic group represents a naphthyl group, a tetrahydronaphthyl group, a C3 group) —C8 cycloalkyl, indanyl, aryl, 9 —oxycarbonyl, adamantyl or fluorenyl, substituted carbocyclyl: optionally selected from a halogen atom, C 1 —C 4 alkyl, Cl —C 4 haloalkyl, substituted C 1 —C 4 alkyl, C 2 —C 4 alkenyl, C 2 —C 4 halo, C 2 —C 4 alkynyl, C 2 —C 4 acetylenyl, C 3 —C 8 cycloalkyl, C 3 — C8 _ ring alkyl, C1 - C3 alkoxy, C1 - C3 halogen alkoxy, C1 - C3 sulphur-based, C1-C3 haloalkylthio, C1-C3 alkylsulfinyl, C1-C3 haloalkylsulfinyl, C1-C3 alkylsulfonyl, C1-C3 haloalkyl Sulfhydryl, C1 - C4 alkylamino, di C1 - C3 acryl, cyano, nitrate &gt;, trans, C1 - C4 alkyl, ci - C4 halocarbonyl, C1 - C4 alkylcarbonyl , C1 - C4 ii alkylcarbonyloxy, C1 - C4 alkoxycarbonyl, C1 - C4 haloalkyloxy, C1 - C4 alkylamine, C1 - C4 haloalkyl, C1-C4 alkylsulfonate One or more substituents which may be the same or different among the oxy group, the C—C 4 haloalkyl group, the arylsulfonyloxy group, the pentafluorosulfoxy group or the phenyl group (wherein the sloped ring group represents a naphthyl group, Tetrahydronaphthyl, C3-C8 cycloalkyl, indanyl, fluorenyl, 9-hydroxy fluorenyl, adamantyl or fluorenyl), hetero-based (in this case, the heterogeneous table is not 11)比 基 吼, 吼 定 定 、, N 一 吼 、, pyrimidinyl, hydrazine, furyl, thienyl, oxazolyl, isoxazolyl, oxadiazolyl, thiazolyl, isothiazolyl, thia Diazolyl, pyrrolyl, imidazolyl, triazolyl, oxazolyl, tetrazolyl Benzothiazolyl, benzoxazolyl, benzofuranyl, benzothienyl, quinolyl, isoquinolinyl, fluorenyl, isodecyl, 1 Η 异, fluorenyl, 2, 3 Dihydromonobenzo[1,4]dioxinyl, benzo[1,3]dioxazolyl, tetrahydropyranyl or dihydropiperidyl), substituted heterocyclic: optionally selected from halogen Atom, Cl-C4 alkyl, C1-C4 haloalkyl, substituted anthracene - €4 alkyl, 02~〇4 alkenyl, 02 - €4 haloalkenyl, C2 - C4 alkynyl, C2 - C4 halo Alkynyl, C3~C8 cycloalkyl, C3-C8-cycloalkyl, C1-C3 alkoxy, C1-C3 halogen alkoxy, Cl-C3 sulfur-burning, C1-193 200836629 200836629 % C3 halogen-burning sulfur group, Cl-C3 alkyl sulphate, fluorene-based, C1-C3 alkylsulfonyl, C1-C3 haloalkyl fluorenyl, C1-C4 alkylamine, two C1-C4 amine, cyano, schiffyl, thiol, C1-C4 succinyl, C1 - C4 aryl group, C1 - C4 decyloxy, C1 - C4 aryloxy, ci - C4 Oxygen carbonyl, C1-C4 halogen-oxygen group, Cl-C4-burning carbonyl group, C1-C4 halogen-burning carbonyl group, Cl-C4 sulphur-based oxy-oxyl group, Cl-C4 halogen-based sulfonyloxy group And one or more substituents which are the same or different among the arylsulfonyloxy group, the pentasil group or the phenyl group (herein represented by a heterocyclic group. a phenanthrenyl group, a bite group, an N-oxide group) , P dense 17 fixed base, Talqyl, 11 phoranyl, porphinyl, 4 sinyl, iso-indolyl, Jinji Junji, sulfhydryl, isoindole, one. Sit-base, σ Bilo Base, p m sigma, diwax, bis. sityl, tetra-tr., benzothiazolyl, benzoxazolyl, benzofuranyl, benzothienyl, quinolyl, isoindole Porphyrin group, bow! Noise base, isodecyl group, 1H-isodecyl group, 2 , 3-dihydro-benzo[1,4]dioxin, benzo[cut carbazolyl, tetrahydropyranyl or dihydropiperidyl), C1-C6 alkyl, or Substituted C1 - C6 alkyl group - selected from a halogen atom, C1 - C4 haloalkyl, c ~ C4 = group, C2 - C4 haloalkenyl group, C2 - C4 alkynyl group, C2 - C4 haloalkynyl group, C: Di-C8 cycloalkyl, C3-C8 halocycloalkyl, C1-C3 alkoxy, C1-C3 halooxy, C1-C3 alkylthio, ci-C3 haloalkylthio, C1-C3 alkyl Sulfonyl, C3 haloalkylsulfinyl, C1_C@yltrixyl, haloalkyl and molybdenum, Cl-f 4 amine, di C1_C4 acryl, cyano, nitro, thiol, carbonyl, Cl-C4 haloalkylcarbonyl, C1-C4 alkylcarbonyloxy, C1-G, methoxy, C1-C4 alkoxy, C1_C4, yttrium, α- 〇卺, 一, C1 - C4 alkyl, acyloxy, C1 - yttrium, sulphate oxy, aromatic fluorenyloxy, pentane sulphur 6 phenyl or the same or more than one substituent in the phenyl group} . A method for preventing a mosquito-killing mosquito is characterized in that the insecticidal composition of the patent application No. 1 to 7 7trl is applied to a plant seed. The cup H harm prevention method is characterized in that the killing green product of the patent application range 1 to 7 is not _ child_. 194 200836629 10. The method of the insect treasure according to item 9 of the patent scope is applied to the seed prevention method, in which the plant species are contacted. Touching the seed shell, processing, immersion treatment or powder coating 11. If the patent is covered by the insect pest, corn, soybean, red bean, and Γ ^ 其中 ^ Among them, the scorpion seed is idiot, cucurbit ri J: rice The seeds of beets, wheat, barley, sunflower, and sauerkraut, taro, simmering, simmering in the sweet pepper and edible golden scented bulbs.甘Gan 4, rhyme of the species, edible lily or meal 12. For example, the morphological transformation of the pests in the scope of patent application section u. And a method for preserving any one of the K-plant seeds, wherein the insecticidal composition of any one of the seven items is applied to the plant seed. The fresh 14-shaped chicks are fresh and green, and the method for the seed seed is spray treatment, smear treatment, coating I treatment, powder coating treatment or fumigation fumigation treatment. Further, the method of L1 is characterized in that the political candle composition according to any one of claims 1 to 7 is applied to a harvest of an agricultural plant. 17. The method for preserving the harvest of claim 16 wherein the harvesting method of the plant is spray coating, smearing treatment, coating treatment: soaking treatment, powder coating treatment, fumigation fumigation treatment or pressing injection. Η&quot;一,图: None. 195