TW200845963A - Compounds with a combination of cannabinoid-CB1 antagonism and serotonin reuptake inhibition - Google Patents

Compounds with a combination of cannabinoid-CB1 antagonism and serotonin reuptake inhibition Download PDF

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Publication number: TW200845963A
Authority: TW; Taiwan
Prior art keywords: compound; group; formula; disease; atom
Prior art date: 2007-01-10

Application number

TW097100554A

Other languages

English (en)

Chinese (zh)

Inventor

Josephus H M Lange

Cornelis G Kruse

Original Assignee

Solvay Pharm Bv

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2007-01-10

Filing date

2008-01-07

Publication date

2008-12-01

2008-01-07 Application filed by Solvay Pharm Bv filed Critical Solvay Pharm Bv

2008-12-01 Publication of TW200845963A publication Critical patent/TW200845963A/zh

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Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/06—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

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TW097100554A 2007-01-10 2008-01-07 Compounds with a combination of cannabinoid-CB1 antagonism and serotonin reuptake inhibition TW200845963A (en)

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EP07100323		2007-01-10

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CN (1)	CN101809000A (pt)
AR (1)	AR064765A1 (pt)
BR (1)	BRPI0806452A2 (pt)
MX (1)	MX2009007405A (pt)
SA (1)	SA08280759B1 (pt)
TW (1)	TW200845963A (pt)

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Publication number	Priority date	Publication date	Assignee	Title
US8580768B2 (en) *	2010-11-18	2013-11-12	Jenrin Discovery, Inc.	Cannabinoid receptor antagonists-inverse agonists useful for treating metabolic disorders, including obesity and diabetes
CN104666291A (zh) *	2013-11-26	2015-06-03	山东绿叶制药有限公司	去甲基文拉法辛苯甲酸酯类化合物在制备改善性功能障碍药物中的应用
WO2017205399A1 (en) *	2016-05-25	2017-11-30	Minerva Neurosciences, Inc.	(2s)-1-[4-(3,4-dichlorophenyl)piperidin-l-yl]-3-[2-(5-methyl-l,3,4-oxadiazol-2-yl)benzo[b]furan-4-yloxy]propan-2-ol or its metabolite for treating anxiety disorders
KR102036909B1 (ko) *	2017-11-28	2019-10-25	한국과학기술원	신규 디스토니아 치료용 약학적 조성물
CN112955145A (zh)	2018-09-04	2021-06-11	密涅瓦神经科学有限公司	使用苯氧丙胺化合物治疗疼痛的方法
MX2022009507A (es) *	2020-02-06	2022-11-09	London Pharmaceuticals And Res Corporation	Ésteres de sulfato de cannabinoides, sus sales y usos de los mismos.

2008
- 2008-01-06 SA SA8280759A patent/SA08280759B1/ar unknown
- 2008-01-07 TW TW097100554A patent/TW200845963A/zh unknown
- 2008-01-07 AR ARP080100048A patent/AR064765A1/es not_active Application Discontinuation
- 2008-01-09 CN CN200880001916A patent/CN101809000A/zh active Pending
- 2008-01-09 MX MX2009007405A patent/MX2009007405A/es unknown
- 2008-01-09 BR BRPI0806452-0A patent/BRPI0806452A2/pt not_active IP Right Cessation

Also Published As

Publication number	Publication date
AR064765A1 (es)	2009-04-22
SA08280759B1 (ar)	2011-05-04
BRPI0806452A2 (pt)	2011-09-06
CN101809000A (zh)	2010-08-18
MX2009007405A (es)	2009-07-17

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