201036660 六、發明說明： 【發明所屬之技術領域】 本發明係關於一藥物輸送裝置；特別 多次不同劑量藥物的藥物輸送裝置。 3、 【先前技術】 市面上有許多藥物輸送裝置像是注射考，古 二特徵和/或功能，能夠安全、可靠、簡便$ 3 = Ο ❹ 輸送特定劑量給使用者。 直覺地 辦力輸送裝置其—缺點乃因大量增加零件來 :些功能可能為混藥、預沖、穿刺ί 物輪^縮回、注射針的覆蓋等任Κ壬多種。樂 加的複雜度，造成很難 # :二 精確度，耐受性和/或高價姑 古二J罪功肊和 增加了藥物輸送裝置的成本。’1^二③所當然的 二,嘗試是為了在合理的程度上 圓=塞=螺=以劑二- 需要許多零件，如箱& = ΐ5後犯夠行注射操作， 而旋轉。 , 預防劑量5又疋圓筒相對於;^塞桿 【發明内容】 用少最主要目的為補救以上問題且接供& 實用且多功能的藥仏、置一此 的特徵來；裝置的專利範圍獨立項 成本發明更佳的實施方式成為此專利 4 201036660 範圍附屬項的標的。 、、根據本發明的主要觀點，其特徵在於一藥物輸 ^裝置，包括一管狀末端外殼有一阻壁和一第一末 端一管狀近側外殼有相對的近側和末端；一藥 物容器在管狀近侧外殼内，該藥物容器包括一軸^ 和一輸送構件，一藥物室將藥物封於其中，和一可 軸向β動且可密封的瓶塞；一螺紋中空柱塞桿有一 該瓶塞接觸；一彈力裝置預先伸縮於柱塞201036660 VI. Description of the Invention: [Technical Field] The present invention relates to a drug delivery device; in particular, a drug delivery device for a plurality of different doses of a drug. 3, [Prior Art] There are many drug delivery devices on the market like injection test, Gu 2 features and / or functions, can be safe, reliable and simple $ 3 = Ο 输送 deliver a specific dose to the user. Intuitively, the power transmission device has the disadvantage of adding a large number of parts: some functions may be mixed, pre-punched, puncture, retracted, and covered with needles. The complexity of Lejia makes it difficult to #:2 precision, tolerance and/or high cost and increase the cost of the drug delivery device. ‘1^2 3 of course 2, the attempt is to a reasonable extent circle = plug = screw = agent 2 - requires many parts, such as box & = ΐ5 after committing the injection operation, and rotating. , preventive dose 5 and 疋 cylinder relative to; ^ plug rod [invention content] The main purpose of using less is to remedy the above problems and to supply & practical and multifunctional medicine, set one of the characteristics; device patent Scope Independent Item Costs A better embodiment of the invention becomes the subject of the scope of this patent 4 201036660. According to a primary aspect of the present invention, a drug delivery device includes a tubular end housing having a barrier wall and a first end and a tubular proximal housing having opposite proximal and distal ends; a drug container in the tubular vicinity In the side casing, the medicine container comprises a shaft and a conveying member, a medicine chamber encloses the medicine therein, and an axially movable and sealable stopper; a threaded hollow plunger rod has a contact with the stopper; An elastic device is pre-expanded to the plunger
ίϋί第一近产壁和該第一末端壁之間；啟動裝 動於非藥物輸送狀態（當啟動裝置與螺欲中 兄下)和藥物輸送狀態(當啟動裝 二螺紋中工柱塞桿脫離的情況 ❹塞桿且可 和^定該螺旋末端外殼的阻壁接觸時） 阻壁有一特旋轉移動(當該第二近側端與 劑詈v 離時，以致該特定距離符合一特定 螺紋中空柱塞桿由於= 可從机丨5置被線性移開，以致劑量設定裝置也 從^疋劑I位置被線性移到停止位置。 當螺紋睹在：多觀點中有-優勢是 物輸送操作所需的零‘數:兒’減少了劑量設定和藥 柱塞桿:ηπ,時撐柱 中空柱塞桿售合彈性舌狀物與螺紋 口而破支撐住’此舌狀物可被 5 201036660 鈕脫離。此辦法亦可減少零件數。 附圖些和其他優勢’從以下詳細說明和 【實施方式】 在目前的應用中，末端，音指筚 離使用者最“二⑵ =最=端樂物輪送裝置或是構件在注射時離使 Ο Ο 外殼ΐι中H的一藥物輸送裝置，包括-管狀末端 154. iff 一阻壁16、160和一第一末端壁28、 筚物容it η 管狀近侧外殼内，該 ，物乂，括—軸，13、113和—輸送構件18、 一樂物室將藥物封於其中，和一可軸向滑動且 :么，的瓶塞20、130; —螺紋中空柱塞桿36、128 Ϊ二近侧壁與該瓶塞接觸；一彈力裝置46、158預 縮於柱塞桿36、128中在該第一近侧壁和該第 28、154之間；一啟動裝置30、122可於 ，枭物輸送狀態（當該啟動裝置與該螺紋中空柱塞 I ί合時）和藥物輸送狀態（當該啟動裝置脫離該螺 、、’中，柱塞桿時）間移動；一劑量設定裝置44、14Θ ，一第二近側和一第二末端，該劑量設定裝置帶螺 次，被置於該螺紋中空柱塞桿且可在停止位置（當 ί f ΐ*近側端與該螺旋末端外殼的阻壁接觸時）和 一設定劑量位置間旋轉移動（當該第二近側端與阻 ，有一特定距離時，以致該特定距離符合一特定劑 I);且藉此，靠著從非藥物輸送狀態到藥物輸送狀 態啟動該啟動裝置，該螺紋中空柱塞桿由於預先伸 縮的彈簀裝置被線性移開，以致劑量設定裝置也可 6 201036660 從設定劑量位置被線性移到停止位置。 管狀近側外殼10、110的近側備有一 114於-頸16、116於輸送構件上，以致—4 : 18、118可被裝上，如螺紋。然而其他藥 = 件如喷嘴、注射口等等，亦可被本發 用&者 吕狀末細外忒11包括一第一末端部位 少一縱向延伸狹縫24，且該螺紋中空 Ο ❹ 螺紋脊38可縱向的移入至少H 二再三t:第—末端部位22備有外部螺紋二1 置於t設44是一管狀套管帶螺旋地被安 置於至少一末端螺紋脊38(圖三）。 女 螺紋中空柱塞桿36的至少一 在其上表面(圖二)。這些以也 面上的内螺紋42緊密配合，此2/之=裝曰置^4内 鈕（圖二）。 兀傻蚺之為劑1設定旋 ，動裝置30包括一鬆開按鈕％延 末端分22前的管狀末端外磚肉 、第 紐32有一鎖件= 口。鬆開按 合，蕻由放知斗勒:肀工柱塞桿的螺紋40嚅 柱塞/的磴鬆開按紐’鎖件被移開與螺紋中允 柱塞^的螺紋40脫離（圖三）。 ”岈，又甲工 藥物輪送裝置欲以以下方式 卷 、， ^使用者’螺紋中空柱塞 二^达 藉此它的螺紋與第一末端邱端的位置， 螺紋26緊密配人丄f刀22的末端上的外部 螺旋的聚於保當劑量設定旋紐被 备一麻時，有好且穩定的連接。 12被至於管狀近4的藥物’一藥物容器 S狀近側外殼1G内。接著，管狀近侧外 7 201036660 ，10與管狀末端外殼u連接（圖一和二）。 疋方疋紐44順時針旋轉直到螺紋中空 塞接觸，操作過程中，鬆開按紐= 讓柱塞桿因彈力裝置向前移動。接 = 始或參考處。接著，鬆開按紐32被鬆 ^广」樂物輸送狀態，藉此螺紋中空柱塞桿被鎖 在此軸處。使用者則以旋轉劑量設定旋鈕44來設定ϋ 第一 第一 第一 第一 第一 第一 第一 第一 第一 第一 第一 第一 第一 第一 第一 第一 第一 第一 第一 第一 第一 第一 第一 第一 第一 第一 第一 第一 第一 第一 第一 第一 第一 第一 第一 第一 第一 第一 第一 第一 第一 第一 第一 第一 第一 第一 第一 第一The condition of the damper rod and the damper wall of the screw end housing) has a special rotational movement (when the second proximal end is separated from the agent 詈v, so that the specific distance conforms to a specific thread hollow The plunger rod can be linearly removed from the casing 5 due to the =, so that the dose setting device is also linearly moved from the position of the agent I to the stop position. When the thread is in: many points of view - the advantage is the object transport operation The required zero 'number: child' reduces the dose setting and the drug plunger rod: ηπ, the time column hollow plunger rod sells the elastic tongue and the threaded mouth to break the support 'this tongue can be used by 5 201036660 button This method can also reduce the number of parts. The figures and other advantages 'from the following detailed description and [embodiment] In the current application, the end, the sound refers to the user's most "two (2) = most = end music The wheeling device or the component is separated from the crucible at the time of injection. A drug delivery device of ΐι H, comprising - a tubular end 154. iff a barrier wall 16, 160 and a first end wall 28, a tubular outer casing, the object, a shaft, 13, 113 and - the conveying member 18, a music chamber in which the medicine is sealed, and a stopper 20, 130 which is axially slidable and: - a hollow hollow plunger rod 36, 128 Contacting the stopper; a resilient device 46, 158 is pre-contracted in the plunger rod 36, 128 between the first proximal wall and the 28th, 154; activating device 30, 122 is available for delivery of waste a state (when the activation device is engaged with the threaded hollow plunger I) and a drug delivery state (when the activation device is disengaged from the screw, 'in the plunger rod); a dose setting device 44, 14A, a second proximal side and a second end, the dose setting device is threaded and placed in the threaded hollow plunger rod and is in a stop position (when the proximal end of the ί f ΐ* and the wall of the spiral end housing Rotational movement between contact and a set dose position (when the second proximal end and the resistance have a certain distance, Causing the specific distance to conform to a specific agent I); and thereby, the activation device is activated by a non-drug delivery state to a drug delivery state, the threaded hollow plunger rod being linearly removed due to the pre-elasticized elastic device The dose setting device can also be linearly moved from the set dose position to the stop position by the 201036660. The proximal side of the tubular proximal housing 10, 110 is provided with a 114-neck 16, 116 on the delivery member such that -4: 18, 118 can It is mounted, such as a thread. However, other medicines such as nozzles, injection ports, etc., may also be used by the present invention, and the first end portion includes a longitudinally extending slit 24, And the threaded hollow ❹ 螺纹 thread ridge 38 can be longitudinally moved into at least H two and three times t: the first end portion 22 is provided with an external thread two 1 placed at the t set 44 is a tubular sleeve with a spirally disposed at least one end thread Ridge 38 (Figure 3). At least one of the female threaded hollow plunger rods 36 is on its upper surface (Fig. 2). These are closely matched by the internal thread 42 on the surface, and the 2/====4 (button 2).兀 蚺 为 剂 剂 剂 剂 剂 剂 剂 剂 剂 剂 剂 剂 剂 剂 设定 设定 设定 设定 设定 设定 设定 设定 设定 设定 设定 设定 设定 设定 设定 设定 设定 设定 设定 设定 设定 设定 设定 设定 设定 设定Release the button, the 斗 蕻 肀 肀 肀 肀 肀 肀 肀 肀 肀 肀 肀 肀 肀 肀 肀 肀 肀 肀 肀 肀 肀 肀 肀 肀 肀 肀 肀 肀 肀 肀 肀 肀 肀 肀 肀 肀 肀 肀 肀 肀 肀). "岈, and the drug delivery device is to be rolled in the following manner, ^ user's threaded hollow plunger is used to reach its position with the thread at the first end and the thread 26 is closely matched with the 刀f knife 22 The outer spiral on the end of the concentrating set is a good and stable connection when the dose setting knob is prepared. 12 is as close as the tubular drug 4 in the S-shaped proximal housing 1G. Then, the tube The proximal outer 7 201036660, 10 is connected to the tubular end shell u (Figs. 1 and 2). The square button turns 44 clockwise until the threaded hollow plug contacts. During operation, release the button = let the plunger rod be elastic Move forward. Connect to the beginning or reference point. Then, release the button 32 to be loosened and conveyed, whereby the threaded hollow plunger rod is locked at the shaft. The user sets the rotary dose setting knob 44
Ο 或硬是Λ定的劑量。由於劑量設定旋鈕的内螺 ^ σ螺、次中空柱塞桿脊上的螺紋40的互動，劑 ^設定旋鈕相對著第一末端部分22從停止位置移 二:ΐ劑里位置。設定劑量旋鈕44被旋轉直到規定 f罝被設定好，第一末端部分22上合適的指標盥劑 篁設定旋鈕上的指示物一同給予指示。之後，注射 針被裝於官狀近側外殼1 〇的頸部16。 於是病人將輸送構件置於預期的藥物輸送部 射器以針刺入皮膚，且從非藥物輸送狀態到 樂物輸送狀態啟動啟動機制3〇，藉此鎖件34被從 螺紋中空柱塞桿36的螺紋40移開，以致螺紋中空 ^塞桿因彈力裝置46之力可自由地向裝置近側線 生移，，依次造成瓶塞向裝置近侧移動，藉此設定 好的藥物劑量經由輸送構件被嘴出。當劑量設定旋 鈕的第二近側與該管狀末端外殼11之阻壁接觸 時^結束藥物輸送。在此該阻壁是該管狀末端外殼 的裱狀壁架。現在藥物輸送裝置可從藥物輸送部位 移開。 .一可重設劑量指示物50示於圖四所示之實施 方式的修改。可重設劑量指示物5〇是醫管狀套管包 括劑量指標52外圓周面且包括一末端和一近側。可 重設劑量指示物50環繞於第一末端部分22，有第 一軸位，在此它與劑量設定旋鈕旋轉地鎖住，和第 8 201036660 ΐϊί 1在此它從劑量設定旋紐旋轉地鬆開。當劑 凝紐被轉動，可重設劑量指示物50也跟著轉 ΐίίί定的劑量指標52與管狀末端外殼11上的 翏亏晶標54相互配合（圖四）。 * ^一劑量隨後被輸送，由於彈力裝置，螺紋中 =桿f劑量設定旋紐一起向裝置的近侧線性移 到重设劑量指示物的近側與該管狀末端外殼11 之阻壁接觸為止。 ❹ Ο 紋中空柱塞桿線性移動，重設劑量指示 姑ϊΐ會1日不之前所設定之劑量，即使一劑量還未 宗紅i 了重設定劑量指示物’它相對於劑量設 旦向移動至第二軸位，在此它即可相對於劑 ΐΐίΐίΐ由轉動。因此，使用者旋轉重設劑量 才曰不物直到它回到第一軸位為止。 外本發明另一實施方式。管狀末端 Α 備有許多開口，且在管狀末端外殼112内 *柱少一縱向延伸狹縫125。螺紋中 少一螺紋脊139可縱向移入至 巧設定裝置146是—劑量設定圓筒被螺旋地 Γί至ί—ί紋脊139,且經由該管狀末端外殼112 上的至夕一第一開口 148被使用。 動裝置122包括一環狀套管126有至 少一按鈕124穿過該管狀末端外殼112的至少ΐ第 :二Τ28 2該環狀套管環繞且且沿著螺紋中 杯128 ;月動；一第一環形* 138圍繞 且有許多彈性舌狀物140與螺紋中空柱塞 ^的至少一螺紋脊139嚙合，在此該第一環U ，整合或固定於管狀末端外殼之内 ° 置於環狀套管和第一環狀物之間。 彈簧⑷ 9 201036660 再者，第二環狀物132有許多傾斜的彈性舌狀 物134與管狀末端外殼112内面上的内中心壁136 接觸，螺紋中空柱塞桿128延伸穿過其中（圖七）， 且在此第二環狀物可被整合或固定於該内中心壁。 4員斜的彈性舌狀物134端點與螺紋中空柱塞桿的至 少一螺紋脊139接觸，以防柱塞桿移向裝置末端。 一劑量標示圓筒150藉由該管狀末端外殼112 内面的内螺紋151與該管狀末端外殼112相連 接三該劑量指標圓筒也可鬆開地連接到該劑量設定 圓筒146。當劑量設定圓筒從停止位置被移至設定 ，量位置從一組劑量指標來顯示設定劑量時（經由 官=末端外殼112上的窗口 152於該劑量指標圓筒 之外面上），劑量指標圓筒與該劑量設定圓筒嚙合。 當，量設定圓筒從設定劑量位置移至停止位置時， 劑量指標圓筒脫離該劑量設定圓筒。 ±第一末端壁154可被整合或附接於管狀末端外 殼±的末端。一扭轉彈簧156有一端連接到管狀 末知^殼112，且另一端連接到劑量設定圓筒丨5〇， 以便當它脫離劑量設定圓筒時，劑量指標圓筒可旋 〇 轉，從而重設該劑量指標。 ★實施方式預運行如下。一藥物容器114被插入 管狀近側外殼11 〇内，且外殼兩部分丨丨〇、丨丨2互相 連接。一藥物輸送裝置118附於管狀近侧外殼u〇 頸部16。使用者現在可設定藥物劑量來注射。此動 作可經由第一開口 148旋轉劑量設定圓筒146來完 成。^於螺紋的連接，此旋轉造成劑量設定圓筒146 被，著螺紋中空柱塞丨28轉向裝置末端。劑量設定 圓筒146之第二近侧因此被從管狀末端外殼之阻壁 60移開（圖七）。劑量設定圓筒146和劑量標示圓筒 150間的連接造成後者也會旋轉，於窗口 152顯示 201036660 劑量。因此’使用者旋轉劑量設定圓筒146直到適 當劑量在窗口中被指示。當劑量標示圓筒15〇被旋 轉時，由於劑量標示圓筒和管狀末端外殼上螺紋151 y螺紋的連接，它被移向裝置末端。再者，劑量標 示圓筒150的旋轉造成扭轉彈簧156被伸縮。 Ο Ο 接著使用者將輸送構件置於預被藥物輸送的部 位’至於注射器以針刺入皮膚是在至少一按鈕124 被啟動後。此動作可藉由倚著彈力124滑動至少一 按鈕124向裝置末端來完成。這造成環狀套管126 作用於第一環狀物的舌狀物14〇上，以致舌狀物與 螺紋中空柱塞桿的至少一螺紋脊丨39分開。於是， 因彈力裝置之力，螺紋中空柱塞桿可自由地向裝置 近巧線性移動，藉此瓶塞也會移動，且藥物的設定 劑量經由輸送構件被射出。當劑量設定圓筒的第二 近侧（和螺紋中空柱塞桿一起移動）與管狀末端外殼 之阻壁160接觸時，即停止注射。扭轉彈簧現在使 得劑量標示圓筒旋轉回原來位置。當至少一按鈕124 ^鬆巧，環狀套管126被彈簧142移回原來位置， ^此第一環狀物的舌狀物140自由向内收縮且再與 螺紋柱塞桿的至少一螺紋脊丨39接觸。 、 圖八顯示圖五到圖七的實施方式的一增加功 二自動注射功能於此實施方式很容易。有 、斤f丨二=射針套促動器Π〇有一末端邊174和一 近Η邊176。通常被設計為管狀並備有 =稍微小於裝置的管狀近侧外殼11〇二注; 備可相對外殼滑動。注射針套促動器 ϋ Γί::172相當於管狀近側外殼110的開 11 η *動器ηο的長度以當置於管狀近側外殼 1 〇上日守，注射針套促動 17 〇的圭 至少一梂釦19J勃器1 U的末舳邊174能與 按鈕124接觸為較佳，且注射針套促動器 11 201036660 =J176 J常與注射針118料侧尖端 ^问千面上。當一使用者想要使用自動注射器功能 、、:射動器170滑進管狀近侧外殼110。 ίίί制if?射針套促動器170向末端移動時 卜特定刺人深度時（如注射針套促 動夯no已相對於外殼移動一特定距離，至 Ο 〇 促動器170的末端邊174和至 ί被侧邊的接觸㈣末端移動，以致注 110 ίϊί中ί注射針套促動11 170 #管狀近側外殼 =動益和官狀近侧外殼之間太多的移動。例如^ 近侧外殼110外面可能有一周圍突起，且注 U170内周圍面有相應的突起，以致當Κί 套促動器170被推入管狀近侧外殼11〇時， 一步的互相向末端推移，避免注射針套促動器 向近侧移動而不只避免接觸突起物而已。並且，^ =側外殼可以有兩個周圍突起， ‘ ==:=當裝置被從注射部位移=射 促動器被手動移向近侧方向直到注射針套 被置於管狀近側外殼的突起間為止 藉此注射針套促動器無法朝任何方 預防無意的刺傷。 u此可 has再者，力裝置（無顯示）可備有該注射針套促 動器，以致當裝置被移開注射部位時，注射 動器會被迫移向裝置近側來覆蓋注射針。 套促 12 201036660 圖九顯示本發明的另一新增功能 置備有一最大劑量限制構件丨8〇 爭 裝 構件180包括一環狀構3大劑量限制 外i 112 3至tit溝槽182 ·接該管狀末端 與兮管狀末端外却^110第一開口 148。橫向溝槽182 ϊ;:的縱向延伸溝槽184互相 與溝槽182、184合ί 起物（未顯示） 壁架186，此壁架與劑量圓饩彳 面有一放射狀 ❹ 188合作。 興齊1置圓琦146的周圍延伸壁架 當一特定最大劑量要被設定時， 放射狀突起被置於縱向溝槽18”，Ϊ L向滑動。環狀物移動直到規定輸送的 最大劑1相應位置為止。此位置可被管 !大：外標190和環狀物上的指標192或ί m盖ft向内的突起物相應於劑量被置“ 146 上中。當劑量被設定時，劑量圓筒 伸壁用於劑量圓筒146的周圍延 申壁土 188而手動旋轉。該旋轉造成周圍延伸壁架 ^向末=移動直到它與環狀物18〇的壁架186接 觸為止。因此不可能再進一步移動劑量圓筒。 特別ii讓ΐ變？大劑量困難，當小孩使用裝置時 限•構ί 的最大劑量被設定後’最大劑量 ，構件180可此被一鎖件永久鎖住。鎖件包 栓或一個螺桿，被迫使通過環狀物和外殼的通 分別被摩擦力或螺紋固定住，讓鎖件在無工 -的情況下很難被移動。 I职庄以上描述之實施方式和附圖只被視為本發明 …、限制之範例，且本發明在本專利權範圍内可以許 13 201036660 多方式修改。 【圖式簡單說明】 本發明在以下詳細說明中，各附圖參照如下： 圖一係根據本發明之第一實施方式之侧視圖。 圖二係根據圖一之實施方式之爆炸圖。 圖三係根據圖一之實施方式之侧視截面圖。 圖四係根據圖一之實施方式修改之詳細視圖。 圖五係根據本發明之第二實施方式之侧視圖。 圖六係根據圖五之實施方式之爆炸圖。 圖七係根據圖五之實施方式之側視截面圖。 圖八係根據圖五之實施方式之側視圖，增加自動注 射功能。 圖九係根據圖五之實施方式之變化，有劑量限制構 件0 【主要元件符號說明】 12 114 藥物容器 10 110 管狀近側外 殼 11 112 管狀末端外 殼 36 128 螺紋中空柱塞桿 46 158 彈力裝置 18 118 輸送構件 30 ；122 啟動裝置 44 146 劑量設定裝 置 124 按紐 152 窗 πΟ or hard is a given dose. Due to the interaction of the inner screw σ screw of the dose setting knob and the thread 40 on the ridge of the secondary hollow plunger rod, the agent setting knob is moved from the stop position relative to the first end portion 22: the position in the sputum. The set dose knob 44 is rotated until the prescribed f罝 is set, and the indicator on the appropriate index 篁 setting knob on the first end portion 22 is given together. Thereafter, the injection needle is attached to the neck portion 16 of the proximal proximal housing 1 . The patient then places the delivery member in the intended drug delivery device to needle the skin, and initiates the activation mechanism 3 from the non-drug delivery state to the music delivery state, whereby the lock member 34 is threaded from the threaded hollow plunger rod 36. The thread 40 is removed, so that the threaded hollow plug can be freely moved to the proximal line of the device by the force of the elastic device 46, which in turn causes the stopper to move to the proximal side of the device, whereby the set dose of the drug is via the conveying member. Mouth. The drug delivery is terminated when the second proximal side of the dose setting knob contacts the barrier wall of the tubular end housing 11. Here the barrier wall is a braided ledge of the tubular end housing. The drug delivery device can now be removed from the drug delivery site. A resettable dose indicator 50 is shown in the modification of the embodiment shown in Figure 4. The resettable dose indicator 5 is a medical tubular cannula comprising an outer circumferential surface of the dose indicator 52 and including a distal end and a proximal side. The resettable dose indicator 50 surrounds the first end portion 22, having a first axial position, where it is rotationally locked with the dose setting knob, and the 8th 201036660 ΐϊί 1 where it is rotated from the dose setting knob open. When the agent button is rotated, the resettable dose indicator 50 also cooperates with the reduced dose index 52 on the tubular end housing 11 (Fig. 4). * A dose is then delivered, due to the elastic means, the threaded rod = rod dose setting knob is moved linearly toward the proximal side of the device until the proximal side of the reset dose indicator contacts the barrier wall of the tubular end housing 11. ❹ 纹 The hollow plunger rod moves linearly, resetting the dose indicating that the aunt will not set the dose before 1 day, even if one dose has not been red, the weight setting dose indicator 'it moves relative to the dose The second axis position, where it can be rotated relative to the agent ΐΐίΐίΐ. Therefore, the user rotates the reset dose until it returns to the first axis position. Another embodiment of the present invention. The tubular end Α is provided with a plurality of openings and within the tubular end housing 112. The post has a longitudinally extending slit 125. One of the threads has a threaded ridge 139 that can be moved longitudinally into the setting device 146. The dose setting cylinder is screwed to the ridge 139 and is passed through the first opening 148 on the tubular end housing 112. use. The moving device 122 includes an annular sleeve 126 having at least one button 124 passing through at least the second end of the tubular end housing 112: the second sleeve 28 2 is surrounded by the annular sleeve and along the threaded cup 128; An annular ring 138 surrounds and has a plurality of resilient tongues 140 that engage at least one threaded ridge 139 of the threaded hollow plunger, wherein the first ring U is integrated or secured within the tubular end housing. Between the sleeve and the first annulus. Spring (4) 9 201036660 Further, the second annulus 132 has a plurality of inclined resilient tongues 134 in contact with the inner central wall 136 on the inner surface of the tubular end housing 112 through which the threaded hollow plunger rod 128 extends (Fig. 7) And wherein the second annulus can be integrated or fixed to the inner central wall. The four-pointed, resilient tongue 134 end is in contact with at least one threaded ridge 139 of the threaded hollow plunger rod to prevent the plunger rod from moving toward the end of the device. A dose indicating cylinder 150 is coupled to the tubular end housing 112 by internal threads 151 on the inner surface of the tubular end housing 112. The dose indicator cylinder is also releasably coupled to the dose setting cylinder 146. When the dose setting cylinder is moved from the stop position to the set, the quantity position displays the set dose from a set of dose indicators (via the window 152 on the official end shell 112 on the outer surface of the dose index cylinder), the dose indicator circle The barrel is engaged with the dose setting cylinder. When the volume setting cylinder is moved from the set dose position to the stop position, the dose indicator cylinder is disengaged from the dose setting cylinder. The first end wall 154 can be integrated or attached to the end of the tubular end casing ±. A torsion spring 156 has one end connected to the tubular end casing 112 and the other end connected to the dose setting cylinder 丨5〇 so that when it is disengaged from the dose setting cylinder, the dose index cylinder can be rotated and repositioned The dose indicator. ★ The implementation of the pre-operation is as follows. A drug container 114 is inserted into the tubular proximal housing 11 and the two portions of the housing are connected to each other. A drug delivery device 118 is attached to the tubular proximal housing u〇 neck 16. The user can now set the dose of the drug to be injected. This action can be accomplished by rotating the dose setting cylinder 146 via the first opening 148. ^ In the threaded connection, this rotation causes the dose setting cylinder 146 to be threaded, and the hollow plunger 丨 28 is turned toward the end of the device. The second proximal side of the dose setting cylinder 146 is thus removed from the barrier wall 60 of the tubular end housing (Fig. 7). The connection between the dose setting cylinder 146 and the dose indicating cylinder 150 causes the latter to also rotate, displaying a 201036660 dose at window 152. Thus the user rotates the dose setting cylinder 146 until the appropriate dose is indicated in the window. When the dose indicating cylinder 15 is rotated, it is moved toward the end of the device due to the connection of the dose indicating cylinder and the threaded 151 y thread on the tubular end housing. Further, the rotation of the dose indicating cylinder 150 causes the torsion spring 156 to be expanded and contracted. Ο Ο The user then places the delivery member in the pre-medicated portion' as the syringe is needled into the skin after at least one button 124 has been activated. This action can be accomplished by sliding at least one button 124 against the end of the device against the spring force 124. This causes the annular sleeve 126 to act on the tongue 14 of the first annulus such that the tongue separates from the at least one threaded ridge 39 of the threaded hollow plunger rod. Thus, due to the force of the elastic means, the threaded hollow plunger rod is free to move linearly to the device, whereby the stopper is also moved, and the set dose of the medicine is ejected via the conveying member. The injection is stopped when the second proximal side of the dose setting cylinder (moving with the threaded hollow plunger rod) is in contact with the barrier wall 160 of the tubular end housing. The torsion spring now rotates the dose indicating cylinder back to its original position. When the at least one button 124 is loose, the annular sleeve 126 is moved back to the original position by the spring 142, and the tongue 140 of the first annulus is free to contract inwardly and at least one threaded ridge with the threaded plunger rod丨39 contact. FIG. 8 shows an added work of the embodiment of FIG. 5 to FIG. 7. The automatic injection function is easy in this embodiment. There is a pinch sleeve actuator Π〇 having an end edge 174 and a proximal edge 176. It is usually designed to be tubular and is provided with a tubular proximal housing 11 that is slightly smaller than the device; it is slidable relative to the housing. The needle sleeve actuator ϋ : ί:: 172 corresponds to the length of the tubular proximal housing 110 to be placed on the tubular proximal housing 1 ,, the needle sleeve is actuated 17 〇 It is preferable that the end edge 174 of the 19J device 1 U can be in contact with the button 124, and the needle sleeve actuator 11 201036660 = J176 J is often used with the tip end of the injection needle 118. When a user wants to use the auto-injector function, the actuator 170 slides into the tubular proximal housing 110. When the needle sleeve actuator 170 is moved toward the end, the specific penetration depth (e.g., the needle sleeve actuation 夯 no has moved a certain distance relative to the housing to the end edge 174 of the actuator 170). And to the side of the contact (four) to move, so that the injection of 110 ίϊί ί injection needle sleeve actuation 11 170 # tubular proximal casing = too much movement between the movable and official proximal casing. For example ^ proximal The outer surface of the outer casing 110 may have a peripheral protrusion, and the peripheral surface of the bead U170 has a corresponding protrusion so that when the 促 套 actuator 170 is pushed into the tubular proximal outer casing 11 ,, one end of each other is pushed to avoid the needle urging. The actuator moves proximally and not just to contact the protrusions. Also, the side housing can have two surrounding protrusions, ' ==:= when the device is displaced from the injection section = the actuator is manually moved to the proximal side Direction until the needle sleeve is placed between the protrusions of the tubular proximal housing so that the needle guard cannot prevent unintentional stab wounds from any side. u This can be again, the force device (no display) can be equipped with this Injection needle sleeve actuator, so that when the device When the injection site is removed, the syringe is forced to move toward the proximal side of the device to cover the injection needle. 201036660 Figure 9 shows another new feature of the present invention with a maximum dose limiting member 丨8〇 contending member 180 Included is a ring-shaped 3 large dose limiting outer i 112 3 to tap groove 182. The first end opening 148 is connected to the tubular end and the tubular end. The lateral grooves 182 :; In conjunction with the grooves 182, 184 (not shown), the ledge 186 cooperates with the radial ❹ 188 of the dose circle. The Xingqi 1 sets the surrounding wall of the 146 to be a specific maximum When the dose is to be set, the radial projections are placed in the longitudinal grooves 18", and the ΪL direction slides. The annulus moves until the corresponding position of the maximum agent 1 for delivery is specified. This position can be managed! Large: external standard 190 and The index 192 on the ring or the inward projection of the ft cover ft is set to "146". When the dose is set, the dose cylinder extends for the surrounding wall 188 of the dose cylinder 146. And manually rotate. This rotation causes the surrounding extension wall frame ^ End = move until it comes into contact with the ledge 186 of the loop 18 。. Therefore it is impossible to move the dose cylinder further. Special ii let ΐ change? Dose difficulty is difficult, when the child uses the device time limit • The maximum dose of ί After setting the 'maximum dose, the member 180 can be permanently locked by a lock. The lock wrap or a screw is forced through the ring and the outer casing to be fixed by friction or thread, respectively, so that the lock is in the absence It is difficult to be moved in the case of the work. The embodiments and the drawings described above are only considered as examples of the invention, the limitations, and the invention can be modified in many ways within the scope of this patent. BRIEF DESCRIPTION OF THE DRAWINGS In the following detailed description, the drawings are referred to the following: FIG. 1 is a side view of a first embodiment according to the invention. Figure 2 is an exploded view of the embodiment of Figure 1. Figure 3 is a side cross-sectional view of the embodiment of Figure 1. Figure 4 is a detailed view of a modification in accordance with the embodiment of Figure 1. Figure 5 is a side view of a second embodiment of the present invention. Figure 6 is an exploded view of the embodiment of Figure 5. Figure 7 is a side cross-sectional view of the embodiment of Figure 5. Figure 8 is an illustration of the side view of the embodiment of Figure 5, with the addition of an automatic injection function. Figure 9 is a variation of the embodiment according to Figure 5, with a dose limiting member 0 [Major component symbol description] 12 114 Drug container 10 110 Tubular proximal housing 11 112 Tubular end housing 36 128 Threaded hollow plunger rod 46 158 Elastic device 18 118 conveying member 30; 122 starting device 44 146 dose setting device 124 button 152 window π