TW201124427A - IL-1 binding proteins - Google Patents

IL-1 binding proteins Download PDF

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Publication number
TW201124427A
TW201124427A TW099135501A TW99135501A TW201124427A TW 201124427 A TW201124427 A TW 201124427A TW 099135501 A TW099135501 A TW 099135501A TW 99135501 A TW99135501 A TW 99135501A TW 201124427 A TW201124427 A TW 201124427A
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TW
Taiwan
Prior art keywords
disease
seq
binding protein
antibody
human
Prior art date
Application number
TW099135501A
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English (en)
Chinese (zh)
Inventor
Chung-Ming Hsieh
Cheng-Bin Wu
Miller Renee
Dominic J Ambrosi
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Abbott Lab
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Publication of TW201124427A publication Critical patent/TW201124427A/zh

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244—Interleukins [IL]
    • C07K16/245—IL-1
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
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    • A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
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    • C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
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    • C07K2317/565—Complementarity determining region [CDR]
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    • C—CHEMISTRY; METALLURGY
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    • G—PHYSICS
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    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
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    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/52—Assays involving cytokines
    • G01N2333/54—Interleukins [IL]
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UY32949A (es) 2011-02-28
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