TW201309343A - 經改善親水性藥物之藥物移行性之水性組成物 - Google Patents

經改善親水性藥物之藥物移行性之水性組成物 Download PDF

Info

Publication number
TW201309343A
TW201309343A TW101104139A TW101104139A TW201309343A TW 201309343 A TW201309343 A TW 201309343A TW 101104139 A TW101104139 A TW 101104139A TW 101104139 A TW101104139 A TW 101104139A TW 201309343 A TW201309343 A TW 201309343A
Authority
TW
Taiwan
Prior art keywords
aqueous composition
drug
acid
present
hydrophilic drug
Prior art date
Application number
TW101104139A
Other languages
English (en)
Chinese (zh)
Inventor
稻垣孝司
堀部吉偉
中田雄一郎
Original Assignee
參天製藥股份有限公司
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by 參天製藥股份有限公司 filed Critical 參天製藥股份有限公司
Publication of TW201309343A publication Critical patent/TW201309343A/zh

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
    • A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
    • A61K31/7076—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/186—Quaternary ammonium compounds, e.g. benzalkonium chloride or cetrimide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A61K9/0051—Ocular inserts or implants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
TW101104139A 2011-02-10 2012-02-09 經改善親水性藥物之藥物移行性之水性組成物 TW201309343A (zh)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2011027431 2011-02-10

Publications (1)

Publication Number Publication Date
TW201309343A true TW201309343A (zh) 2013-03-01

Family

ID=46638701

Family Applications (1)

Application Number Title Priority Date Filing Date
TW101104139A TW201309343A (zh) 2011-02-10 2012-02-09 經改善親水性藥物之藥物移行性之水性組成物

Country Status (3)

Country Link
JP (1) JP2012180346A (fr)
TW (1) TW201309343A (fr)
WO (1) WO2012108489A1 (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL2919755T3 (pl) * 2012-11-19 2018-07-31 Bausch & Lomb Incorporated Wodna ciekła kompozycja zawierająca kwas 2-amino-3-(4-bromobenzoilo)fenylooctowy
CA2935055C (fr) 2014-01-10 2021-08-24 Santen Pharmaceutical Co., Ltd. Composition pharmaceutique contenant un compose acide pyridylamino-acetique
WO2022075472A1 (fr) * 2020-10-09 2022-04-14 アイ・セラピーズ・エル・エル・シー Préparation liquide de brimonidine

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE63392B1 (en) * 1988-02-08 1995-04-19 Insite Vision Inc Ophthalmic suspensions
SE9401108D0 (sv) * 1994-03-31 1994-03-31 Leiras Oy Ophthalmic composition I
JPH11130675A (ja) * 1997-08-29 1999-05-18 Santen Pharmaceut Co Ltd クロマン誘導体含有点眼液
WO2003082257A2 (fr) * 2002-03-28 2003-10-09 Sucampo Ag Methode de traitement de l'hypertension oculaire et du glaucome
JP5382972B2 (ja) * 2003-12-26 2014-01-08 ロート製薬株式会社 粘度低下が防止された組成物
JP5301069B2 (ja) * 2004-04-15 2013-09-25 ロート製薬株式会社 アズレン含有水性液剤
JP2008266143A (ja) * 2007-04-16 2008-11-06 Santen Pharmaceut Co Ltd アデノシン誘導体を有効成分として含有する緑内障治療剤

Also Published As

Publication number Publication date
JP2012180346A (ja) 2012-09-20
WO2012108489A1 (fr) 2012-08-16

Similar Documents

Publication Publication Date Title
US11439652B2 (en) Ophthalmic aqueous composition
KR20190013877A (ko) 아트로핀-함유 수성 조성물
TWI650127B (zh) 含吡啶基胺基乙酸化合物之醫藥組成物
TWI822690B (zh) 用於治療近視之組合物及方法
JPWO2008096804A1 (ja) ラタノプロスト含有点眼剤
KR20140056280A (ko) 비마토프로스트 및 브리모니딘의 고정된 용량 조합
EP2525793B1 (fr) Agoniste alpha-2-adrénergique ayant un effet de réduction de la pression intra-oculaire de longue durée
JP2014504645A (ja) 緑内障の治療のための組成物および方法
HK1220632A1 (zh) 含有聚乙二醇的组合物
TW201309343A (zh) 經改善親水性藥物之藥物移行性之水性組成物
WO2004024164A1 (fr) Gouttes ophtalmiques stables contenant comme principe actif du latanoprost
TW201902472A (zh) 含有艾瑞布林或其藥劑學上允許的鹽之注射劑
WO2023152642A1 (fr) Compositions ophtalmiques et procédés associés
JP2025123496A (ja) エピナスチン又はその塩を含有する水性組成物
US20140275197A1 (en) Alpha-2 adrenergic agonist for treating intraocular pressure and ocular diseases through intravitreal and intracameral routes
JP2007016024A (ja) ロフルミラスト点眼液
JP7118579B1 (ja) エピナスチン又はその塩を含有する水性組成物
JP5460996B2 (ja) 眼科用剤
TW201836611A (zh) 含有他氟前列素及檸檬酸酯之緩釋劑
TW201726127A (zh) 含有多佐胺、高分子及硼酸之醫藥組成物
US20130210876A1 (en) Alpha-2 adrenergic agonist having long duration of intraocular pressure-lowering effect
BR112019003945B1 (pt) Composições oftálmicas compreendendo 2,4-dimetilbenzoato de 4-(3- amino-1-(isoquinolina-6-ilamino)-1-oxopropan-2-il)benzila
HK1238174A1 (en) Ophthalmic aqueous composition