TW201722444A - 重組李斯特菌疫苗菌株及在癌症免疫治療中使用該菌株之方法 - Google Patents

重組李斯特菌疫苗菌株及在癌症免疫治療中使用該菌株之方法 Download PDF

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Publication number: TW201722444A
Authority: TW; Taiwan
Prior art keywords: another embodiment; antigen; protein; recombinant; llo
Prior art date: 2015-10-14

Application number

TW105133303A

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English (en)

Chinese (zh)

Inventor

羅伯特佩提

凱爾派瑞

Original Assignee

艾法西斯公司

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2015-10-14

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2016-10-14

Publication date

2017-07-01

2016-10-14 Application filed by 艾法西斯公司 filed Critical 艾法西斯公司

2017-07-01 Publication of TW201722444A publication Critical patent/TW201722444A/zh

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- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
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- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
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- C07K2319/00—Fusion polypeptide
- C07K2319/20—Fusion polypeptide containing a tag with affinity for a non-protein ligand
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- C—CHEMISTRY; METALLURGY
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- C07K2319/00—Fusion polypeptide
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- C12N2710/00011—Details
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- C12N2710/00011—Details
- C12N2710/20011—Papillomaviridae
- C12N2710/20034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein

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TW105133303A 2015-10-14 2016-10-14 重組李斯特菌疫苗菌株及在癌症免疫治療中使用該菌株之方法 TW201722444A (zh)

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US (1)	US20180280487A1 (fr)
EP (1)	EP3368675A1 (fr)
JP (1)	JP2018530588A (fr)
KR (1)	KR20180056782A (fr)
CN (1)	CN108368513A (fr)
AU (1)	AU2016340148A1 (fr)
CA (1)	CA3001702A1 (fr)
IL (1)	IL258563A (fr)
MA (1)	MA43124A (fr)
MX (1)	MX2018004598A (fr)
SG (1)	SG11201802913VA (fr)
TW (1)	TW201722444A (fr)
WO (1)	WO2017066706A1 (fr)

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AU2012229218B2 (en)	2011-03-11	2017-03-02	Advaxis, Inc.	Listeria-based adjuvants
CN104411327A (zh)	2012-03-12	2015-03-11	阿德瓦希斯公司	李斯特菌疫苗治疗以后的抑制细胞功能抑制
US10143734B2 (en)	2014-02-18	2018-12-04	Advaxis, Inc.	Biomarker directed multi-target immunotherapy
SG11201608820WA (en)	2014-04-24	2016-11-29	Advaxis Inc	Recombinant listeria vaccine strains and methods of producing the same
MA41644A (fr)	2015-03-03	2018-01-09	Advaxis Inc	Compositions à base de listeria comprenant un système d'expression de minigènes codant pour des peptides, et leurs procédés d'utilisation
AU2016339022B2 (en)	2015-10-12	2020-09-10	Nantomics, Llc	Iterative discovery of neoepitopes and adaptive immunotherapy and methods therefor
JP7197481B2 (ja)	2016-11-30	2022-12-27	アドバクシス，インコーポレイテッド	反復性がん突然変異を標的とする免疫原性組成物およびその使用の方法
AR110730A1 (es) *	2017-01-05	2019-04-24	Advaxis Inc	Vacunas de cepas recombinantes de listeria y método para usarlas en inmunoterapia de cáncer
JP7284156B2 (ja)	2017-09-19	2023-05-30	アドバクシス，インコーポレイテッド	細菌またはＬｉｓｔｅｒｉａ株の凍結乾燥のための組成物および方法
CN109010819B (zh) *	2018-08-06	2022-05-10	南京颂悦生物科技有限公司	重组减毒李斯特菌在制备宫颈癌治疗性疫苗中的应用
CN111334521B (zh) *	2018-12-18	2022-02-18	上海若泰医药科技有限公司	一种提高非整合减毒李斯特菌外源抗原蛋白表达的方法
CN111349645B (zh) *	2018-12-24	2022-05-17	上海若泰医药科技有限公司	一种提高非整合减毒李斯特菌疫苗安全性的方法
JP7125760B2 (ja) *	2019-06-14	2022-08-25	国立研究開発法人理化学研究所	免疫系を賦活化する細胞および当該細胞を含む医薬組成物
GB202019767D0 (en)	2020-12-15	2021-01-27	Chain Biotechnology Ltd	Compostitions and methods
CN120230776B (zh) *	2025-05-29	2025-08-26	深圳市青华检验有限公司	多价表达的绵羊李斯特菌宫颈癌疫苗及其制备方法

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US8114414B2 (en) *	1994-11-08	2012-02-14	The Trustees Of The University Of Pennsylvania	Compositions and methods for treatment of cervical cancer
US8956621B2 (en) *	1994-11-08	2015-02-17	The Trustees Of The University Of Pennsylvania	Compositions and methods for treatment of cervical dysplasia
US8771702B2 (en) *	2001-03-26	2014-07-08	The Trustees Of The University Of Pennsylvania	Non-hemolytic LLO fusion proteins and methods of utilizing same
US20110129499A1 (en) *	2008-05-19	2011-06-02	Paulo Maciag	Dual delivery system for heterologous antigens
US20160220652A1 (en) *	2015-02-03	2016-08-04	Advaxis, Inc.	Methods of using recombinant listeria vaccine strains in disease immunotherapy

2016
- 2016-10-14 EP EP16856367.4A patent/EP3368675A1/fr not_active Withdrawn
- 2016-10-14 JP JP2018519326A patent/JP2018530588A/ja active Pending
- 2016-10-14 CN CN201680071389.6A patent/CN108368513A/zh active Pending
- 2016-10-14 CA CA3001702A patent/CA3001702A1/fr not_active Abandoned
- 2016-10-14 MX MX2018004598A patent/MX2018004598A/es unknown
- 2016-10-14 TW TW105133303A patent/TW201722444A/zh unknown
- 2016-10-14 SG SG11201802913VA patent/SG11201802913VA/en unknown
- 2016-10-14 WO PCT/US2016/057220 patent/WO2017066706A1/fr not_active Ceased
- 2016-10-14 KR KR1020187013256A patent/KR20180056782A/ko not_active Withdrawn
- 2016-10-14 MA MA043124A patent/MA43124A/fr unknown
- 2016-10-14 US US15/767,625 patent/US20180280487A1/en not_active Abandoned
- 2016-10-14 AU AU2016340148A patent/AU2016340148A1/en not_active Abandoned
2018
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Publication number	Publication date
CN108368513A (zh)	2018-08-03
IL258563A (en)	2018-05-31
MX2018004598A (es)	2018-11-29
AU2016340148A1 (en)	2018-05-31
SG11201802913VA (en)	2018-05-30
JP2018530588A (ja)	2018-10-18
US20180280487A1 (en)	2018-10-04
WO2017066706A1 (fr)	2017-04-20
CA3001702A1 (fr)	2017-04-20
EP3368675A1 (fr)	2018-09-05
MA43124A (fr)	2018-09-05
WO2017066706A8 (fr)	2018-05-17
KR20180056782A (ko)	2018-05-29

Publication	Publication Date	Title
JP7300041B2 (ja)	2023-06-28	組み換え型リステリアワクチン株およびこれを生産する方法
US10010593B2 (en)	2018-07-03	Recombinant Listeria vaccine strains and methods of using the same in cancer immunotherapy
TW201722444A (zh)	2017-07-01	重組李斯特菌疫苗菌株及在癌症免疫治療中使用該菌株之方法
US20160220652A1 (en)	2016-08-04	Methods of using recombinant listeria vaccine strains in disease immunotherapy
JP2018527382A (ja)	2018-09-20	組み換え型リステリアワクチン株および癌免疫療法におけるその使用方法