TW201733982A - 芳香醯胺類衍生物、其製備方法及其在醫藥上的應用 - Google Patents
芳香醯胺類衍生物、其製備方法及其在醫藥上的應用 Download PDFInfo
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- NKUANJWLZORYEK-UHFFFAOYSA-N methyl 1-cyclopropyl-2-[[4-(trifluoromethoxy)phenyl]methyl]indole-5-carboxylate Chemical compound COC(=O)C=1C=C2C=C(N(C2=CC=1)C1CC1)CC1=CC=C(C=C1)OC(F)(F)F NKUANJWLZORYEK-UHFFFAOYSA-N 0.000 description 1
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- PFAMEYPFSCQBGZ-UHFFFAOYSA-N methyl 1-ethyl-2-[[2-fluoro-4-(trifluoromethyl)phenyl]methyl]indole-5-carboxylate Chemical compound CCn1c(Cc2ccc(cc2F)C(F)(F)F)cc2cc(ccc12)C(=O)OC PFAMEYPFSCQBGZ-UHFFFAOYSA-N 0.000 description 1
- ZKQVECZXLLGWET-UHFFFAOYSA-N methyl 1-ethyl-2-[[4-(trifluoromethoxy)phenyl]methyl]indole-5-carboxylate Chemical compound CCn1c(Cc2ccc(OC(F)(F)F)cc2)cc2cc(ccc12)C(=O)OC ZKQVECZXLLGWET-UHFFFAOYSA-N 0.000 description 1
- MCXKKDGBTDQLNH-UHFFFAOYSA-N methyl 1-ethyl-2-[[4-(trifluoromethyl)phenyl]methyl]indole-5-carboxylate Chemical compound CCn1c(Cc2ccc(cc2)C(F)(F)F)cc2cc(ccc12)C(=O)OC MCXKKDGBTDQLNH-UHFFFAOYSA-N 0.000 description 1
- SQHTUMVTWCYRAX-UHFFFAOYSA-N methyl 1-ethyl-2-[[6-(trifluoromethyl)pyridin-3-yl]methyl]indole-5-carboxylate Chemical compound CCn1c(Cc2ccc(nc2)C(F)(F)F)cc2cc(ccc12)C(=O)OC SQHTUMVTWCYRAX-UHFFFAOYSA-N 0.000 description 1
- MAWMIWRQOXGCAC-UHFFFAOYSA-N methyl 1-methyl-2-[[4-(trifluoromethoxy)phenyl]methyl]indole-5-carboxylate Chemical compound COC(=O)C=1C=C2C=C(N(C2=CC=1)C)CC1=CC=C(C=C1)OC(F)(F)F MAWMIWRQOXGCAC-UHFFFAOYSA-N 0.000 description 1
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- LUJVYTLWPMOFBN-UHFFFAOYSA-N methyl 1-propan-2-yl-2-[[4-(trifluoromethyl)phenyl]methyl]indole-5-carboxylate Chemical compound COC(=O)C=1C=C2C=C(N(C2=CC=1)C(C)C)CC1=CC=C(C=C1)C(F)(F)F LUJVYTLWPMOFBN-UHFFFAOYSA-N 0.000 description 1
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- ZGPDJPIOUJOLRQ-UHFFFAOYSA-N methyl 2-[[2-(trifluoromethoxy)phenyl]methyl]-1H-indole-5-carboxylate Chemical compound COC(=O)C=1C=C2C=C(NC2=CC=1)CC1=C(C=CC=C1)OC(F)(F)F ZGPDJPIOUJOLRQ-UHFFFAOYSA-N 0.000 description 1
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- YJVFFLUZDVXJQI-UHFFFAOYSA-L palladium(ii) acetate Chemical compound [Pd+2].CC([O-])=O.CC([O-])=O YJVFFLUZDVXJQI-UHFFFAOYSA-L 0.000 description 1
- 239000012188 paraffin wax Substances 0.000 description 1
- 125000001147 pentyl group Chemical group C(CCCC)* 0.000 description 1
- 239000003208 petroleum Substances 0.000 description 1
- 239000000825 pharmaceutical preparation Substances 0.000 description 1
- 230000003285 pharmacodynamic effect Effects 0.000 description 1
- ZUOUZKKEUPVFJK-UHFFFAOYSA-N phenylbenzene Natural products C1=CC=CC=C1C1=CC=CC=C1 ZUOUZKKEUPVFJK-UHFFFAOYSA-N 0.000 description 1
- 229910000073 phosphorus hydride Inorganic materials 0.000 description 1
- 102000020233 phosphotransferase Human genes 0.000 description 1
- 230000035790 physiological processes and functions Effects 0.000 description 1
- 125000003386 piperidinyl group Chemical group 0.000 description 1
- 125000005592 polycycloalkyl group Polymers 0.000 description 1
- 238000000039 preparative column chromatography Methods 0.000 description 1
- 230000002335 preservative effect Effects 0.000 description 1
- 239000000651 prodrug Substances 0.000 description 1
- 229940002612 prodrug Drugs 0.000 description 1
- 239000001294 propane Substances 0.000 description 1
- 125000006308 propyl amino group Chemical group 0.000 description 1
- QQONPFPTGQHPMA-UHFFFAOYSA-N propylene Natural products CC=C QQONPFPTGQHPMA-UHFFFAOYSA-N 0.000 description 1
- 125000004805 propylene group Chemical group [H]C([H])([H])C([H])([*:1])C([H])([H])[*:2] 0.000 description 1
- QELSKZZBTMNZEB-UHFFFAOYSA-N propylparaben Chemical compound CCCOC(=O)C1=CC=C(O)C=C1 QELSKZZBTMNZEB-UHFFFAOYSA-N 0.000 description 1
- 125000004309 pyranyl group Chemical group O1C(C=CC=C1)* 0.000 description 1
- 125000003373 pyrazinyl group Chemical group 0.000 description 1
- 125000000719 pyrrolidinyl group Chemical group 0.000 description 1
- 125000000168 pyrrolyl group Chemical group 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 229930002330 retinoic acid Natural products 0.000 description 1
- CVHZOJJKTDOEJC-UHFFFAOYSA-N saccharin Chemical compound C1=CC=C2C(=O)NS(=O)(=O)C2=C1 CVHZOJJKTDOEJC-UHFFFAOYSA-N 0.000 description 1
- 229940081974 saccharin Drugs 0.000 description 1
- 235000019204 saccharin Nutrition 0.000 description 1
- 239000000901 saccharin and its Na,K and Ca salt Substances 0.000 description 1
- 230000028327 secretion Effects 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 239000008159 sesame oil Substances 0.000 description 1
- 235000011803 sesame oil Nutrition 0.000 description 1
- 230000001568 sexual effect Effects 0.000 description 1
- 239000000741 silica gel Substances 0.000 description 1
- 229910002027 silica gel Inorganic materials 0.000 description 1
- 210000003491 skin Anatomy 0.000 description 1
- 235000010413 sodium alginate Nutrition 0.000 description 1
- 239000000661 sodium alginate Substances 0.000 description 1
- 229940005550 sodium alginate Drugs 0.000 description 1
- 239000012279 sodium borohydride Substances 0.000 description 1
- 229910000033 sodium borohydride Inorganic materials 0.000 description 1
- 229910001467 sodium calcium phosphate Inorganic materials 0.000 description 1
- 235000019812 sodium carboxymethyl cellulose Nutrition 0.000 description 1
- 229920001027 sodium carboxymethylcellulose Polymers 0.000 description 1
- 239000011780 sodium chloride Substances 0.000 description 1
- 239000001488 sodium phosphate Substances 0.000 description 1
- 235000010265 sodium sulphite Nutrition 0.000 description 1
- WNRREQPZEBZGFA-UHFFFAOYSA-M sodium;4-cyanobenzenesulfinate Chemical compound [Na+].[O-]S(=O)C1=CC=C(C#N)C=C1 WNRREQPZEBZGFA-UHFFFAOYSA-M 0.000 description 1
- UWIVVFQECQYHOB-UHFFFAOYSA-M sodium;ethanesulfinate Chemical compound [Na+].CCS([O-])=O UWIVVFQECQYHOB-UHFFFAOYSA-M 0.000 description 1
- 239000007901 soft capsule Substances 0.000 description 1
- 239000000600 sorbitol Substances 0.000 description 1
- 239000003549 soybean oil Substances 0.000 description 1
- 235000012424 soybean oil Nutrition 0.000 description 1
- 239000008347 soybean phospholipid Substances 0.000 description 1
- 239000008107 starch Substances 0.000 description 1
- 235000019698 starch Nutrition 0.000 description 1
- 239000008117 stearic acid Substances 0.000 description 1
- 238000003756 stirring Methods 0.000 description 1
- 238000007920 subcutaneous administration Methods 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- PXQLVRUNWNTZOS-UHFFFAOYSA-N sulfanyl Chemical compound [SH] PXQLVRUNWNTZOS-UHFFFAOYSA-N 0.000 description 1
- 229910052717 sulfur Inorganic materials 0.000 description 1
- 239000011593 sulfur Substances 0.000 description 1
- 239000000829 suppository Substances 0.000 description 1
- 238000013268 sustained release Methods 0.000 description 1
- 239000012730 sustained-release form Substances 0.000 description 1
- 238000001308 synthesis method Methods 0.000 description 1
- 239000000454 talc Substances 0.000 description 1
- 235000012222 talc Nutrition 0.000 description 1
- 229910052623 talc Inorganic materials 0.000 description 1
- VCIAOUHISLYQEY-UHFFFAOYSA-N tert-butyl 2-butyl-4-oxopiperidine-1-carboxylate Chemical compound CCCCC1CC(=O)CCN1C(=O)OC(C)(C)C VCIAOUHISLYQEY-UHFFFAOYSA-N 0.000 description 1
- KLKBCNDBOVRQIJ-UHFFFAOYSA-N tert-butyl 4-(aminomethyl)piperidine-1-carboxylate Chemical compound CC(C)(C)OC(=O)N1CCC(CN)CC1 KLKBCNDBOVRQIJ-UHFFFAOYSA-N 0.000 description 1
- ULSJZPNDNPDOJY-UHFFFAOYSA-N tert-butyl 4-[[[1-cyclopropyl-2-[[4-(trifluoromethyl)phenyl]methyl]indole-5-carbonyl]amino]methyl]piperidine-1-carboxylate Chemical compound CC(C)(C)OC(=O)N1CCC(CNC(=O)c2ccc3n(C4CC4)c(Cc4ccc(cc4)C(F)(F)F)cc3c2)CC1 ULSJZPNDNPDOJY-UHFFFAOYSA-N 0.000 description 1
- AWPCEINAMMEODJ-UHFFFAOYSA-N tert-butyl N-[(4-ethylsulfonyl-2-fluorophenyl)methyl]carbamate Chemical compound C(C)(C)(C)OC(NCC1=C(C=C(C=C1)S(=O)(=O)CC)F)=O AWPCEINAMMEODJ-UHFFFAOYSA-N 0.000 description 1
- VHYXAWLOJGIJPC-UHFFFAOYSA-N tert-butyl n-(piperidin-4-ylmethyl)carbamate Chemical compound CC(C)(C)OC(=O)NCC1CCNCC1 VHYXAWLOJGIJPC-UHFFFAOYSA-N 0.000 description 1
- DTYUGOHKMHFOMT-UHFFFAOYSA-N tert-butyl n-[(4-bromo-2-fluorophenyl)methyl]carbamate Chemical compound CC(C)(C)OC(=O)NCC1=CC=C(Br)C=C1F DTYUGOHKMHFOMT-UHFFFAOYSA-N 0.000 description 1
- CWXPZXBSDSIRCS-UHFFFAOYSA-N tert-butyl piperazine-1-carboxylate Chemical compound CC(C)(C)OC(=O)N1CCNCC1 CWXPZXBSDSIRCS-UHFFFAOYSA-N 0.000 description 1
- 125000003718 tetrahydrofuranyl group Chemical group 0.000 description 1
- 125000001712 tetrahydronaphthyl group Chemical group C1(CCCC2=CC=CC=C12)* 0.000 description 1
- 125000003507 tetrahydrothiofenyl group Chemical group 0.000 description 1
- 125000000383 tetramethylene group Chemical group [H]C([H])([*:1])C([H])([H])C([H])([H])C([H])([H])[*:2] 0.000 description 1
- VLLMWSRANPNYQX-UHFFFAOYSA-N thiadiazole Chemical compound C1=CSN=N1.C1=CSN=N1 VLLMWSRANPNYQX-UHFFFAOYSA-N 0.000 description 1
- 239000002562 thickening agent Substances 0.000 description 1
- 125000004568 thiomorpholinyl group Chemical group 0.000 description 1
- 229940098465 tincture Drugs 0.000 description 1
- 229960000984 tocofersolan Drugs 0.000 description 1
- 230000002103 transcriptional effect Effects 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
- 229960001727 tretinoin Drugs 0.000 description 1
- 125000000876 trifluoromethoxy group Chemical group FC(F)(F)O* 0.000 description 1
- RYFMWSXOAZQYPI-UHFFFAOYSA-K trisodium phosphate Chemical compound [Na+].[Na+].[Na+].[O-]P([O-])([O-])=O RYFMWSXOAZQYPI-UHFFFAOYSA-K 0.000 description 1
- 230000004614 tumor growth Effects 0.000 description 1
- RSJKGSCJYJTIGS-UHFFFAOYSA-N undecane Chemical compound CCCCCCCCCCC RSJKGSCJYJTIGS-UHFFFAOYSA-N 0.000 description 1
- 125000000391 vinyl group Chemical group [H]C([*])=C([H])[H] 0.000 description 1
- 239000003643 water by type Substances 0.000 description 1
- 239000002076 α-tocopherol Substances 0.000 description 1
- 235000004835 α-tocopherol Nutrition 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/12—Radicals substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
- C07D235/10—Radicals substituted by halogen atoms or nitro radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
- C07D235/12—Radicals substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610158675 | 2016-03-18 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TW201733982A true TW201733982A (zh) | 2017-10-01 |
Family
ID=59850085
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TW106109163A TW201733982A (zh) | 2016-03-18 | 2017-03-20 | 芳香醯胺類衍生物、其製備方法及其在醫藥上的應用 |
Country Status (3)
| Country | Link |
|---|---|
| CN (1) | CN107531679B (fr) |
| TW (1) | TW201733982A (fr) |
| WO (1) | WO2017157332A1 (fr) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TW201906816A (zh) * | 2017-07-06 | 2019-02-16 | 大陸商江蘇恆瑞醫藥股份有限公司 | 吲哚甲醯胺類衍生物、其製備方法及其在醫藥上的應用 |
| EP3683206A4 (fr) * | 2017-09-12 | 2021-01-13 | Jiangsu Hengrui Medicine Co., Ltd. | Dérivé d'indole-formamide substitué par un atome de deutérium, son procédé de préparation et ses applications médicales |
| WO2020011147A1 (fr) * | 2018-07-10 | 2020-01-16 | Sunshine Lake Pharma Co., Ltd. | ANTAGONISTE DE RORγ ET SON UTILISATION EN MÉDECINE |
| CN110872243B (zh) * | 2018-08-31 | 2023-03-31 | 四川科伦博泰生物医药股份有限公司 | 磺酰胺类化合物、其制备方法及用途 |
| WO2020140960A1 (fr) * | 2019-01-04 | 2020-07-09 | 江苏恒瑞医药股份有限公司 | Forme cristalline pour dérivé d'indole-formamide et procédé de préparation de la forme cristalline |
| TW202100513A (zh) * | 2019-03-11 | 2021-01-01 | 大陸商江蘇恒瑞醫藥股份有限公司 | 氘原子取代的吲哚甲酰胺類衍生物的晶型及其製備方法 |
| CN110151760B (zh) * | 2019-06-06 | 2022-02-11 | 上海海洋大学 | 双吲哚化合物fgfc1在制备抗非小细胞肺癌药物中的应用 |
| CA3155875A1 (fr) * | 2019-09-30 | 2021-04-08 | Shanghai Litedd Co., Ltd. | Compose de biaryle substitue par sulfo ou sel correspondant, son procede de preparation et son utilisation |
| CN112745268B (zh) * | 2019-10-31 | 2022-09-16 | 江苏恒瑞医药股份有限公司 | 苯并咪唑衍生物的晶型及制备方法 |
| TW202146381A (zh) * | 2020-05-15 | 2021-12-16 | 大陸商上海輝启生物醫藥科技有限公司 | 可用作RORγ調節劑的聯芳基類化合物 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ZA825413B (en) * | 1981-08-26 | 1983-06-29 | Pfizer | Thromboxane synthetase inhibitors, processes for their production, and pharmaceutical compositions comprising them |
| PA8535601A1 (es) * | 2000-12-21 | 2002-11-28 | Pfizer | Derivados benzimidazol y piridilimidazol como ligandos para gabaa |
| SE0101387D0 (sv) * | 2001-04-20 | 2001-04-20 | Astrazeneca Ab | Novel compounds |
| US7820682B2 (en) * | 2002-10-03 | 2010-10-26 | Ono Pharmaceutical Co., Ltd. | LPA receptor antagonist |
| KR20090024115A (ko) * | 2006-04-12 | 2009-03-06 | 에프. 호프만-라 로슈 아게 | 5-아미도-2-카복스아마이드 인돌 |
| WO2010051245A1 (fr) * | 2008-11-03 | 2010-05-06 | Merck Sharp & Dohme Corp. | Benzimidazole et aza-benzimidazole carboxamides |
| HRP20151258T1 (hr) * | 2009-08-07 | 2016-02-26 | Chugai Seiyaku Kabushiki Kaisha | Derivat aminopirazola |
| AU2010289353B2 (en) * | 2009-09-03 | 2016-12-08 | Allergan, Inc. | Compounds as tyrosine kinase modulators |
| US8883789B2 (en) * | 2011-12-14 | 2014-11-11 | Boehringer Ingelheim International Gmbh | Piperazine derivatives and their use as positive allosteric modulators of mGluR5 receptors |
| WO2014044738A1 (fr) * | 2012-09-21 | 2014-03-27 | Sanofi | Dérivés d'amide d'acide benzimidazole-carboxylique utilisés comme modulateurs du récepteur apj |
| WO2015175845A1 (fr) * | 2014-05-15 | 2015-11-19 | Peloton Therapeutics, Inc. | Dérivés de benzimidazole et leurs utilisations |
| DK3331876T3 (da) * | 2015-08-05 | 2021-01-11 | Vitae Pharmaceuticals Llc | Modulators of ror-gamma |
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2017
- 2017-03-17 CN CN201780001328.7A patent/CN107531679B/zh active Active
- 2017-03-17 WO PCT/CN2017/077114 patent/WO2017157332A1/fr not_active Ceased
- 2017-03-20 TW TW106109163A patent/TW201733982A/zh unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CN107531679B (zh) | 2021-07-02 |
| WO2017157332A1 (fr) | 2017-09-21 |
| CN107531679A (zh) | 2018-01-02 |
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