TW293783B - - Google Patents

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Info

Publication number: TW293783B
Authority: TW; Taiwan
Prior art keywords: channel; flow; distribution; bed; fluid bed
Prior art date: 1995-06-16

Application number

TW085106551A

Other languages

English (en)

Chinese (zh)

Original Assignee

Ciba Geigy Ag

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-06-16

Filing date

1996-06-01

Publication date

1996-12-21

1996-06-01 Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag

1996-12-21 Application granted granted Critical

1996-12-21 Publication of TW293783B publication Critical patent/TW293783B/zh

Links

238000009826 distribution Methods 0.000 claims description 80
239000000126 substance Substances 0.000 claims description 70
239000012530 fluid Substances 0.000 claims description 42
239000000463 material Substances 0.000 claims description 32
230000009969 flowable effect Effects 0.000 claims description 9
239000000203 mixture Substances 0.000 claims description 9
239000012526 feed medium Substances 0.000 claims description 4
238000011161 development Methods 0.000 claims description 3
230000002093 peripheral effect Effects 0.000 claims description 3
230000002950 deficient Effects 0.000 claims description 2
238000007689 inspection Methods 0.000 claims description 2
240000005979 Hordeum vulgare Species 0.000 claims 1
235000007340 Hordeum vulgare Nutrition 0.000 claims 1
208000003251 Pruritus Diseases 0.000 claims 1
238000009434 installation Methods 0.000 claims 1
238000000034 method Methods 0.000 description 15
238000004458 analytical method Methods 0.000 description 8
238000009792 diffusion process Methods 0.000 description 7
238000004519 manufacturing process Methods 0.000 description 6
238000005516 engineering process Methods 0.000 description 5
238000012545 processing Methods 0.000 description 5
101000905241 Mus musculus Heart- and neural crest derivatives-expressed protein 1 Proteins 0.000 description 4
230000002079 cooperative effect Effects 0.000 description 4
239000002609 medium Substances 0.000 description 4
241000894007 species Species 0.000 description 4
238000006243 chemical reaction Methods 0.000 description 3
238000013461 design Methods 0.000 description 3
238000005259 measurement Methods 0.000 description 3
239000004065 semiconductor Substances 0.000 description 3
239000012141 concentrate Substances 0.000 description 2
230000018109 developmental process Effects 0.000 description 2
238000010586 diagram Methods 0.000 description 2
239000006185 dispersion Substances 0.000 description 2
238000001459 lithography Methods 0.000 description 2
238000004377 microelectronic Methods 0.000 description 2
238000007639 printing Methods 0.000 description 2
238000000926 separation method Methods 0.000 description 2
230000003068 static effect Effects 0.000 description 2
VZSRBBMJRBPUNF-UHFFFAOYSA-N 2-(2,3-dihydro-1H-inden-2-ylamino)-N-[3-oxo-3-(2,4,6,7-tetrahydrotriazolo[4,5-c]pyridin-5-yl)propyl]pyrimidine-5-carboxamide Chemical compound C1C(CC2=CC=CC=C12)NC1=NC=C(C=N1)C(=O)NCCC(N1CC2=C(CC1)NN=N2)=O VZSRBBMJRBPUNF-UHFFFAOYSA-N 0.000 description 1
241000894006 Bacteria Species 0.000 description 1
208000004350 Strabismus Diseases 0.000 description 1
230000001133 acceleration Effects 0.000 description 1
238000009825 accumulation Methods 0.000 description 1
238000001467 acupuncture Methods 0.000 description 1
238000013019 agitation Methods 0.000 description 1
230000003796 beauty Effects 0.000 description 1
239000008280 blood Substances 0.000 description 1
210000004369 blood Anatomy 0.000 description 1
230000000875 corresponding effect Effects 0.000 description 1
-1 cutting procedures Chemical compound 0.000 description 1
238000005520 cutting process Methods 0.000 description 1
230000007812 deficiency Effects 0.000 description 1
238000001514 detection method Methods 0.000 description 1
238000005553 drilling Methods 0.000 description 1
238000003891 environmental analysis Methods 0.000 description 1
239000011521 glass Substances 0.000 description 1
239000002241 glass-ceramic Substances 0.000 description 1
230000012447 hatching Effects 0.000 description 1
238000004898 kneading Methods 0.000 description 1
239000007788 liquid Substances 0.000 description 1
239000007769 metal material Substances 0.000 description 1
238000005459 micromachining Methods 0.000 description 1
238000000465 moulding Methods 0.000 description 1
239000002245 particle Substances 0.000 description 1
229920000642 polymer Polymers 0.000 description 1
238000004321 preservation Methods 0.000 description 1
230000035484 reaction time Effects 0.000 description 1
210000003625 skull Anatomy 0.000 description 1
230000007958 sleep Effects 0.000 description 1
239000007787 solid Substances 0.000 description 1
238000003892 spreading Methods 0.000 description 1
238000003756 stirring Methods 0.000 description 1

Classifications

- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F25/00—Flow mixers; Mixers for falling materials, e.g. solid particles
- B01F25/40—Static mixers
- B01F25/42—Static mixers in which the mixing is affected by moving the components jointly in changing directions, e.g. in tubes provided with baffles or obstructions
- B01F25/421—Static mixers in which the mixing is affected by moving the components jointly in changing directions, e.g. in tubes provided with baffles or obstructions by moving the components in a convoluted or labyrinthine path
- B01F25/422—Static mixers in which the mixing is affected by moving the components jointly in changing directions, e.g. in tubes provided with baffles or obstructions by moving the components in a convoluted or labyrinthine path between stacked plates, e.g. grooved or perforated plates
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
- B01F33/00—Other mixers; Mixing plants; Combinations of mixers
- B01F33/30—Micromixers
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J19/0093—Microreactors, e.g. miniaturised or microfabricated reactors
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00781—Aspects relating to microreactors
- B01J2219/00783—Laminate assemblies, i.e. the reactor comprising a stack of plates
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00781—Aspects relating to microreactors
- B01J2219/00889—Mixing
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0809—Geometry, shape and general structure rectangular shaped
- B01L2300/0816—Cards, e.g. flat sample carriers usually with flow in two horizontal directions
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
- B01L2300/0867—Multiple inlets and one sample wells, e.g. mixing, dilution
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
- B01L2300/0874—Three dimensional network
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
- B01L2400/0406—Moving fluids with specific forces or mechanical means specific forces capillary forces

Landscapes

Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Dispersion Chemistry (AREA)
Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Analytical Chemistry (AREA)
General Health & Medical Sciences (AREA)
Hematology (AREA)
Clinical Laboratory Science (AREA)
Feeding, Discharge, Calcimining, Fusing, And Gas-Generation Devices (AREA)

TW085106551A 1995-06-16 1996-06-01 TW293783B (fr)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
EP95810405		1995-06-16

Publications (1)

Publication Number	Publication Date
TW293783B true TW293783B (fr)	1996-12-21

Family

ID=8221761

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
TW085106551A TW293783B (fr)	1995-06-16	1996-06-01

Country Status (5)

Country	Link
EP (1)	EP0833688A1 (fr)
AU (1)	AU6005196A (fr)
TW (1)	TW293783B (fr)
WO (1)	WO1997000125A1 (fr)
ZA (1)	ZA965075B (fr)

Families Citing this family (54)

* Cited by examiner, † Cited by third party
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US6454945B1 (en)	1995-06-16	2002-09-24	University Of Washington	Microfabricated devices and methods
US5716852A (en) *	1996-03-29	1998-02-10	University Of Washington	Microfabricated diffusion-based chemical sensor
US5948684A (en) *	1997-03-31	1999-09-07	University Of Washington	Simultaneous analyte determination and reference balancing in reference T-sensor devices
US6541213B1 (en)	1996-03-29	2003-04-01	University Of Washington	Microscale diffusion immunoassay
EP0981408B1 (fr) *	1997-05-16	2004-04-21	Alberta Research Council	Systeme microfluidique et ses utilisations
US6632619B1 (en)	1997-05-16	2003-10-14	The Governors Of The University Of Alberta	Microfluidic system and methods of use
US6007775A (en)	1997-09-26	1999-12-28	University Of Washington	Multiple analyte diffusion based chemical sensor
US6136272A (en) *	1997-09-26	2000-10-24	University Of Washington	Device for rapidly joining and splitting fluid layers
EP1309404A2 (fr)	2000-08-07	2003-05-14	Nanostream, Inc.	Melangeur fluidique pour systeme microfluidique
US6890093B2 (en)	2000-08-07	2005-05-10	Nanostream, Inc.	Multi-stream microfludic mixers
US6919046B2 (en)	2001-06-07	2005-07-19	Nanostream, Inc.	Microfluidic analytical devices and methods
US6877892B2 (en)	2002-01-11	2005-04-12	Nanostream, Inc.	Multi-stream microfluidic aperture mixers
US6845787B2 (en) *	2002-02-23	2005-01-25	Nanostream, Inc.	Microfluidic multi-splitter
US20100022414A1 (en)	2008-07-18	2010-01-28	Raindance Technologies, Inc.	Droplet Libraries
GB0307428D0 (en)	2003-03-31	2003-05-07	Medical Res Council	Compartmentalised combinatorial chemistry
GB0307403D0 (en)	2003-03-31	2003-05-07	Medical Res Council	Selection by compartmentalised screening
US20060078893A1 (en)	2004-10-12	2006-04-13	Medical Research Council	Compartmentalised combinatorial chemistry by microfluidic control
US20050221339A1 (en)	2004-03-31	2005-10-06	Medical Research Council Harvard University	Compartmentalised screening by microfluidic control
US7550267B2 (en)	2004-09-23	2009-06-23	University Of Washington	Microscale diffusion immunoassay utilizing multivalent reactants
US7968287B2 (en)	2004-10-08	2011-06-28	Medical Research Council Harvard University	In vitro evolution in microfluidic systems
JP4715403B2 (ja) *	2005-09-08	2011-07-06	株式会社日立プラントテクノロジー	マイクロ化学反応装置
EP1984738A2 (fr)	2006-01-11	2008-10-29	Raindance Technologies, Inc.	Dispositifs microfluidiques et leurs procédés d'utilisation dans la formation et le contrôle de nanoréacteurs
EP4190448A3 (fr)	2006-05-11	2023-09-20	Bio-Rad Laboratories, Inc.	Dispositifs microfluidiques
US9562837B2 (en)	2006-05-11	2017-02-07	Raindance Technologies, Inc.	Systems for handling microfludic droplets
US9012390B2 (en)	2006-08-07	2015-04-21	Raindance Technologies, Inc.	Fluorocarbon emulsion stabilizing surfactants
JP2008043912A (ja) *	2006-08-21	2008-02-28	Hitachi Ltd	マイクロリアクタ
US8772046B2 (en)	2007-02-06	2014-07-08	Brandeis University	Manipulation of fluids and reactions in microfluidic systems
US8592221B2 (en)	2007-04-19	2013-11-26	Brandeis University	Manipulation of fluids, fluid components and reactions in microfluidic systems
US12038438B2 (en)	2008-07-18	2024-07-16	Bio-Rad Laboratories, Inc.	Enzyme quantification
US8528589B2 (en)	2009-03-23	2013-09-10	Raindance Technologies, Inc.	Manipulation of microfluidic droplets
EP2486409A1 (fr)	2009-10-09	2012-08-15	Universite De Strasbourg	Nanomatériau marqué à base de silice à propriétés améliorées et ses utilisations
EP2517025B1 (fr)	2009-12-23	2019-11-27	Bio-Rad Laboratories, Inc.	Procédés pour réduire l'échange de molécules entre des gouttelettes
US9366632B2 (en)	2010-02-12	2016-06-14	Raindance Technologies, Inc.	Digital analyte analysis
US10351905B2 (en)	2010-02-12	2019-07-16	Bio-Rad Laboratories, Inc.	Digital analyte analysis
US9399797B2 (en)	2010-02-12	2016-07-26	Raindance Technologies, Inc.	Digital analyte analysis
EP4435111A1 (fr)	2010-02-12	2024-09-25	Bio-Rad Laboratories, Inc.	Analyse numérique d'analyte
WO2012045012A2 (fr)	2010-09-30	2012-04-05	Raindance Technologies, Inc.	Dosages sandwich dans des gouttelettes
US9364803B2 (en)	2011-02-11	2016-06-14	Raindance Technologies, Inc.	Methods for forming mixed droplets
EP2675819B1 (fr)	2011-02-18	2020-04-08	Bio-Rad Laboratories, Inc.	Compositions et méthodes de marquage moléculaire
US8841071B2 (en)	2011-06-02	2014-09-23	Raindance Technologies, Inc.	Sample multiplexing
WO2012167142A2 (fr)	2011-06-02	2012-12-06	Raindance Technolgies, Inc.	Quantification d'enzyme
US8658430B2 (en)	2011-07-20	2014-02-25	Raindance Technologies, Inc.	Manipulating droplet size
US11901041B2 (en)	2013-10-04	2024-02-13	Bio-Rad Laboratories, Inc.	Digital analysis of nucleic acid modification
US9944977B2 (en)	2013-12-12	2018-04-17	Raindance Technologies, Inc.	Distinguishing rare variations in a nucleic acid sequence from a sample
WO2015103367A1 (fr)	2013-12-31	2015-07-09	Raindance Technologies, Inc.	Système et procédé de détection d'une espèce d'arn
US10647981B1 (en)	2015-09-08	2020-05-12	Bio-Rad Laboratories, Inc.	Nucleic acid library generation methods and compositions
EP3381531A1 (fr) *	2017-03-31	2018-10-03	Vrije Universiteit Brussel	Distributeur de flux
US11185830B2 (en)	2017-09-06	2021-11-30	Waters Technologies Corporation	Fluid mixer
CN119715878A (zh)	2019-08-12	2025-03-28	沃特世科技公司	用于色谱系统的混合器
EP4179310B1 (fr)	2020-07-07	2025-07-30	Waters Technologies Corporation	Mélangeur pour chromatographie en phase liquide
EP4179311B1 (fr)	2020-07-07	2025-07-30	Waters Technologies Corporation	Agencement de mélangeur combiné pour la réduction de bruit en chromatographie en phase fluide
CN116194767A (zh)	2020-09-22	2023-05-30	沃特世科技公司	连续流混合器
WO2022245566A1 (fr)	2021-05-20	2022-11-24	Waters Technologies Corporation	Mélangeur à écoulement divisé à dispersion égale
EP4359118A1 (fr)	2021-06-23	2024-05-01	Waters Technologies Corporation	Mélangeur de solvant passif pour chromatographie en phase liquide

Family Cites Families (5)

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Publication number	Priority date	Publication date	Assignee	Title
US3382534A (en) *	1965-08-19	1968-05-14	Monsanto Co	Plate type fluid mixer
GB1254150A (en) *	1969-11-28	1971-11-17	Smart & Brown Engineers Ltd	Mixing devices
JPS5134869B1 (fr) *	1971-01-11	1976-09-29
WO1993022058A1 (fr) *	1992-05-01	1993-11-11	Trustees Of The University Of Pennsylvania	Analyse par amplification de polynucleotide a l'aide d'un dispositif micro-fabrique
WO1994021372A1 (fr) *	1993-03-19	1994-09-29	E.I. Du Pont De Nemours And Company	Appareil de traitement chimique integre et procedes de preparation associes

1996
- 1996-06-01 TW TW085106551A patent/TW293783B/zh active
- 1996-06-04 EP EP96917497A patent/EP0833688A1/fr not_active Withdrawn
- 1996-06-04 AU AU60051/96A patent/AU6005196A/en not_active Abandoned
- 1996-06-04 WO PCT/EP1996/002425 patent/WO1997000125A1/fr not_active Ceased
- 1996-06-14 ZA ZA965075A patent/ZA965075B/xx unknown

Also Published As

Publication number	Publication date
AU6005196A (en)	1997-01-15
EP0833688A1 (fr)	1998-04-08
ZA965075B (en)	1996-12-17
WO1997000125A1 (fr)	1997-01-03

Publication	Publication Date	Title
TW293783B (fr)	1996-12-21
JP4991688B2 (ja)	2012-08-01	流体分離装置
JP3634868B2 (ja)	2005-03-30	マイクロミキサ
US6863867B2 (en)	2005-03-08	Apparatus for mixing and reacting at least two fluids
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US6935768B2 (en)	2005-08-30	Method and statistical micromixer for mixing at least two liquids
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JP4803671B2 (ja)	2011-10-26	静止型マイクロミキサー
US7066641B2 (en)	2006-06-27	Micromixer
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