TW314459B - - Google Patents
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- Publication number
- TW314459B TW314459B TW083104029A TW83104029A TW314459B TW 314459 B TW314459 B TW 314459B TW 083104029 A TW083104029 A TW 083104029A TW 83104029 A TW83104029 A TW 83104029A TW 314459 B TW314459 B TW 314459B
- Authority
- TW
- Taiwan
- Prior art keywords
- screw
- vertebral
- foot
- thread
- vertebrae
- Prior art date
Links
- 230000008878 coupling Effects 0.000 claims description 21
- 238000010168 coupling process Methods 0.000 claims description 21
- 238000005859 coupling reaction Methods 0.000 claims description 21
- 210000000988 bone and bone Anatomy 0.000 claims description 13
- 230000000149 penetrating effect Effects 0.000 claims description 5
- 230000009471 action Effects 0.000 claims description 3
- 230000000399 orthopedic effect Effects 0.000 claims description 3
- 239000011295 pitch Substances 0.000 claims 3
- 238000000034 method Methods 0.000 claims 2
- 239000007787 solid Substances 0.000 claims 2
- PCTMTFRHKVHKIS-BMFZQQSSSA-N (1s,3r,4e,6e,8e,10e,12e,14e,16e,18s,19r,20r,21s,25r,27r,30r,31r,33s,35r,37s,38r)-3-[(2r,3s,4s,5s,6r)-4-amino-3,5-dihydroxy-6-methyloxan-2-yl]oxy-19,25,27,30,31,33,35,37-octahydroxy-18,20,21-trimethyl-23-oxo-22,39-dioxabicyclo[33.3.1]nonatriaconta-4,6,8,10 Chemical compound C1C=C2C[C@@H](OS(O)(=O)=O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2.O[C@H]1[C@@H](N)[C@H](O)[C@@H](C)O[C@H]1O[C@H]1/C=C/C=C/C=C/C=C/C=C/C=C/C=C/[C@H](C)[C@@H](O)[C@@H](C)[C@H](C)OC(=O)C[C@H](O)C[C@H](O)CC[C@@H](O)[C@H](O)C[C@H](O)C[C@](O)(C[C@H](O)[C@H]2C(O)=O)O[C@H]2C1 PCTMTFRHKVHKIS-BMFZQQSSSA-N 0.000 claims 1
- 238000002347 injection Methods 0.000 claims 1
- 239000007924 injection Substances 0.000 claims 1
- 238000003780 insertion Methods 0.000 claims 1
- 230000037431 insertion Effects 0.000 claims 1
- 238000011179 visual inspection Methods 0.000 claims 1
- 241001417935 Platycephalidae Species 0.000 description 8
- 238000006073 displacement reaction Methods 0.000 description 8
- 238000001356 surgical procedure Methods 0.000 description 7
- 238000004519 manufacturing process Methods 0.000 description 5
- 230000002441 reversible effect Effects 0.000 description 4
- KJTLSVCANCCWHF-UHFFFAOYSA-N Ruthenium Chemical compound [Ru] KJTLSVCANCCWHF-UHFFFAOYSA-N 0.000 description 3
- 230000008901 benefit Effects 0.000 description 3
- 238000009434 installation Methods 0.000 description 3
- 229910052707 ruthenium Inorganic materials 0.000 description 3
- 208000031481 Pathologic Constriction Diseases 0.000 description 2
- 210000004705 lumbosacral region Anatomy 0.000 description 2
- 210000005036 nerve Anatomy 0.000 description 2
- 230000036262 stenosis Effects 0.000 description 2
- 208000037804 stenosis Diseases 0.000 description 2
- 241000258920 Chilopoda Species 0.000 description 1
- 241000255925 Diptera Species 0.000 description 1
- 240000002853 Nelumbo nucifera Species 0.000 description 1
- 235000006508 Nelumbo nucifera Nutrition 0.000 description 1
- 235000006510 Nelumbo pentapetala Nutrition 0.000 description 1
- 208000002193 Pain Diseases 0.000 description 1
- 208000008765 Sciatica Diseases 0.000 description 1
- 208000007103 Spondylolisthesis Diseases 0.000 description 1
- 241000251539 Vertebrata <Metazoa> Species 0.000 description 1
- 238000004873 anchoring Methods 0.000 description 1
- 230000002146 bilateral effect Effects 0.000 description 1
- 210000003164 cauda equina Anatomy 0.000 description 1
- 230000006835 compression Effects 0.000 description 1
- 238000007906 compression Methods 0.000 description 1
- 230000001054 cortical effect Effects 0.000 description 1
- 230000007423 decrease Effects 0.000 description 1
- 230000003412 degenerative effect Effects 0.000 description 1
- 238000007598 dipping method Methods 0.000 description 1
- 238000004090 dissolution Methods 0.000 description 1
- 206010020718 hyperplasia Diseases 0.000 description 1
- 230000002390 hyperplastic effect Effects 0.000 description 1
- 238000002684 laminectomy Methods 0.000 description 1
- 230000003902 lesion Effects 0.000 description 1
- 229910052751 metal Inorganic materials 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012856 packing Methods 0.000 description 1
- 230000001575 pathological effect Effects 0.000 description 1
- 230000035515 penetration Effects 0.000 description 1
- 230000002093 peripheral effect Effects 0.000 description 1
- 238000002601 radiography Methods 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 230000000472 traumatic effect Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
- A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws or setting implements
- A61B17/68—Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
- A61B17/70—Spinal positioners or stabilisers, e.g. stabilisers comprising fluid filler in an implant
- A61B17/7074—Tools specially adapted for spinal fixation operations other than for bone removal or filler handling
- A61B17/7076—Tools specially adapted for spinal fixation operations other than for bone removal or filler handling for driving, positioning or assembling spinal clamps or bone anchors specially adapted for spinal fixation
- A61B17/7082—Tools specially adapted for spinal fixation operations other than for bone removal or filler handling for driving, positioning or assembling spinal clamps or bone anchors specially adapted for spinal fixation for driving, i.e. rotating, screws or screw parts specially adapted for spinal fixation, e.g. for driving polyaxial or tulip-headed screws
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
- A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws or setting implements
- A61B17/68—Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
- A61B17/70—Spinal positioners or stabilisers, e.g. stabilisers comprising fluid filler in an implant
- A61B17/7001—Screws or hooks combined with longitudinal elements which do not contact vertebrae
- A61B17/7002—Longitudinal elements, e.g. rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
- A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws or setting implements
- A61B17/68—Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
- A61B17/70—Spinal positioners or stabilisers, e.g. stabilisers comprising fluid filler in an implant
- A61B17/7001—Screws or hooks combined with longitudinal elements which do not contact vertebrae
- A61B17/7032—Screws or hooks with U-shaped head or back through which longitudinal rods pass
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
- A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws or setting implements
- A61B17/68—Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
- A61B17/70—Spinal positioners or stabilisers, e.g. stabilisers comprising fluid filler in an implant
- A61B17/7001—Screws or hooks combined with longitudinal elements which do not contact vertebrae
- A61B17/7041—Screws or hooks combined with longitudinal elements which do not contact vertebrae with single longitudinal rod offset laterally from single row of screws or hooks
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
- A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws or setting implements
- A61B17/68—Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
- A61B17/70—Spinal positioners or stabilisers, e.g. stabilisers comprising fluid filler in an implant
- A61B17/7049—Connectors, not bearing on the vertebrae, for linking longitudinal elements together
- A61B17/7052—Connectors, not bearing on the vertebrae, for linking longitudinal elements together of variable angle or length
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
- A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws or setting implements
- A61B17/68—Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
- A61B17/70—Spinal positioners or stabilisers, e.g. stabilisers comprising fluid filler in an implant
- A61B17/7055—Spinal positioners or stabilisers, e.g. stabilisers comprising fluid filler in an implant connected to sacrum, pelvis or skull
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods
- A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
- A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws or setting implements
- A61B17/88—Osteosynthesis instruments; Methods or means for implanting or extracting internal or external fixation devices
- A61B17/8875—Screwdrivers, spanners or wrenches
- A61B17/8886—Screwdrivers, spanners or wrenches holding the screw head
Landscapes
- Health & Medical Sciences (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Neurology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Surgery (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Medical Informatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Neurosurgery (AREA)
- Surgical Instruments (AREA)
- Prostheses (AREA)
- Amplifiers (AREA)
- Measurement Of Force In General (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9213694A FR2697991B1 (fr) | 1992-11-13 | 1992-11-13 | Instrumentation d'ostéosynthèse lombosacrée pour la correction du spondylolisthésis par voie postérieure, et vis d'instrumentation. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TW314459B true TW314459B (no) | 1997-09-01 |
Family
ID=9435531
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TW083104029A TW314459B (no) | 1992-11-13 | 1994-05-04 |
Country Status (13)
| Country | Link |
|---|---|
| EP (1) | EP0668750A4 (no) |
| JP (1) | JP3737825B2 (no) |
| KR (1) | KR950703899A (no) |
| CN (1) | CN1092637A (no) |
| AR (1) | AR248078A1 (no) |
| AU (1) | AU682839B2 (no) |
| CA (1) | CA2149322A1 (no) |
| FI (1) | FI952312A0 (no) |
| FR (1) | FR2697991B1 (no) |
| NO (1) | NO951900L (no) |
| TW (1) | TW314459B (no) |
| WO (1) | WO1994010928A1 (no) |
| ZA (1) | ZA938465B (no) |
Families Citing this family (44)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2716794B1 (fr) * | 1994-03-03 | 1996-05-24 | Sofamor Danek Group Inc | Connecteur pour instrumentation d'ostéosynthèse rachidienne, destiné à une fixation lombaire ou sacrée ou ilio-sacrée. |
| FR2740673B1 (fr) * | 1995-11-07 | 1998-01-23 | Stryker France Sa | Dispositif et ensemble de connexion transverse pour osteosynthese du rachis |
| FR2761876B1 (fr) * | 1997-04-09 | 1999-08-06 | Materiel Orthopedique En Abreg | Instrumentation d'osteosynthese lombaire pour la correction du spondylolisthesis par voie posterieure |
| FR2768610B1 (fr) * | 1997-09-22 | 1999-12-10 | Materiel Orthopedique En Abreg | Vis a os pour dispositifs d'osteosynthese, et procede de fabrication de cette vis |
| WO1999060957A1 (en) | 1998-05-27 | 1999-12-02 | Nuvasive, Inc. | Methods and apparatus for separating and stabilizing adjacent vertebrae |
| US6368325B1 (en) | 1998-05-27 | 2002-04-09 | Nuvasive, Inc. | Bone blocks and methods for inserting bone blocks into intervertebral spaces |
| US6251140B1 (en) | 1998-05-27 | 2001-06-26 | Nuvasive, Inc. | Interlocking spinal inserts |
| CN100376219C (zh) * | 1998-07-06 | 2008-03-26 | 株式会社率高 | 脊椎固定装置 |
| FR2801777B1 (fr) | 1999-12-03 | 2002-02-08 | Spinevision | Fixateur externe dans le domaine de l'osteosynthese rachidienne et l'orthopedie generale |
| DE20010206U1 (de) * | 2000-06-09 | 2001-10-18 | BIOMET MERCK Deutschland GmbH, 14167 Berlin | Aufnahme für eine Pedikelschraube |
| US6852126B2 (en) | 2000-07-17 | 2005-02-08 | Nuvasive, Inc. | Stackable interlocking intervertebral support system |
| US6923814B1 (en) | 2001-10-30 | 2005-08-02 | Nuvasive, Inc. | System and methods for cervical spinal fusion |
| US7618423B1 (en) | 2002-06-15 | 2009-11-17 | Nuvasive, Inc. | System and method for performing spinal fusion |
| FR2856581B1 (fr) * | 2003-06-27 | 2005-08-19 | Medicrea | Materiel d'osteosynthese vertebrale |
| US8308772B2 (en) | 2003-06-27 | 2012-11-13 | Medicrea Technologies | Vertebral osteosynthesis equipment |
| US7918891B1 (en) | 2004-03-29 | 2011-04-05 | Nuvasive Inc. | Systems and methods for spinal fusion |
| USD530423S1 (en) | 2005-03-29 | 2006-10-17 | Nuvasive, Inc. | Intervertebral implant |
| US8328851B2 (en) | 2005-07-28 | 2012-12-11 | Nuvasive, Inc. | Total disc replacement system and related methods |
| USD741488S1 (en) | 2006-07-17 | 2015-10-20 | Nuvasive, Inc. | Spinal fusion implant |
| US7931673B2 (en) * | 2006-12-06 | 2011-04-26 | Zimmer Spine, Inc. | Minimally invasive vertebral anchor access system and associated method |
| US8673005B1 (en) | 2007-03-07 | 2014-03-18 | Nuvasive, Inc. | System and methods for spinal fusion |
| US8083796B1 (en) | 2008-02-29 | 2011-12-27 | Nuvasive, Inc. | Implants and methods for spinal fusion |
| USD599019S1 (en) | 2008-03-07 | 2009-08-25 | Nuvasive, Inc. | Spinal fusion implant |
| USD754346S1 (en) | 2009-03-02 | 2016-04-19 | Nuvasive, Inc. | Spinal fusion implant |
| US9687357B2 (en) | 2009-03-12 | 2017-06-27 | Nuvasive, Inc. | Vertebral body replacement |
| US9387090B2 (en) | 2009-03-12 | 2016-07-12 | Nuvasive, Inc. | Vertebral body replacement |
| US9351845B1 (en) | 2009-04-16 | 2016-05-31 | Nuvasive, Inc. | Method and apparatus for performing spine surgery |
| US8287597B1 (en) | 2009-04-16 | 2012-10-16 | Nuvasive, Inc. | Method and apparatus for performing spine surgery |
| USD731063S1 (en) | 2009-10-13 | 2015-06-02 | Nuvasive, Inc. | Spinal fusion implant |
| US8808335B2 (en) | 2010-03-08 | 2014-08-19 | Miami Device Solutions, Llc | Locking element for a polyaxial bone anchor, bone plate assembly and tool |
| US9198765B1 (en) | 2011-10-31 | 2015-12-01 | Nuvasive, Inc. | Expandable spinal fusion implants and related methods |
| USD721808S1 (en) | 2011-11-03 | 2015-01-27 | Nuvasive, Inc. | Intervertebral implant |
| CN103519878B (zh) * | 2013-10-29 | 2016-03-23 | 宋西正 | 一种微创撬拨整形内固定器 |
| CN105813586B (zh) * | 2013-10-31 | 2020-08-04 | 爱荷华大学研究基金会 | 经皮横向连接器系统 |
| KR101537062B1 (ko) * | 2014-08-11 | 2015-07-16 | 주식회사 코렌텍 | 척추고정장치 |
| JP6867628B2 (ja) | 2016-02-15 | 2021-04-28 | 株式会社アスロメディカル | トランスバース、および手術器具 |
| US10420593B2 (en) * | 2016-07-21 | 2019-09-24 | Warsaw Orthopedic, Inc. | Spinal correction system and method |
| CN107307899A (zh) * | 2016-12-31 | 2017-11-03 | 王文军 | 多节段串联式脊柱外固定装置 |
| US20180228516A1 (en) * | 2017-02-14 | 2018-08-16 | Warsaw Orthopedic, Inc. | Spinal implant system and method |
| CN106963462A (zh) * | 2017-03-23 | 2017-07-21 | 张群 | 用于脊椎手术的外固定装置 |
| US10463404B2 (en) | 2017-07-27 | 2019-11-05 | Warsaw Orthopedic, Inc. | Spinal implant system and method |
| ES3029612T3 (en) * | 2017-10-24 | 2025-06-24 | Paulo Tadeu Maia Cavali | Guide device for attachment and transfixation of sliding plates for dynamic implants |
| FR3124692B1 (fr) * | 2021-07-01 | 2023-12-08 | Distimp | Vis d’ancrage osseux pour dispositif d’ostéosynthèse, ensemble chirurgical pour la connexion de ladite vis audit dispositif d’ostéosynthèse, et lot d’instruments pour la pose dudit ensemble chirurgical. |
| CN116439807A (zh) * | 2023-04-17 | 2023-07-18 | 北京纳通医疗科技控股有限公司 | 脊柱重度畸形矫正器械及系统 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR1322212A (fr) * | 1962-02-12 | 1963-03-29 | Appareil destiné à retirer les broches employées en chirurgie des os | |
| US3604487A (en) * | 1969-03-10 | 1971-09-14 | Richard S Gilbert | Orthopedic screw driving means |
| US4648388B1 (en) * | 1985-11-01 | 1995-10-31 | Acromed Corp | Apparatus and method for maintaining vertebrae in a desired relationship |
| ES2034058T3 (es) * | 1987-07-29 | 1993-04-01 | Acromed Corporation | Un dispositivo implantable por medios quirurgicos para la columna vertebral. |
| US4836196A (en) * | 1988-01-11 | 1989-06-06 | Acromed Corporation | Surgically implantable spinal correction system |
| DE3942326A1 (de) * | 1989-12-21 | 1991-06-27 | Haerle Anton | Schraube als osteosynthesehilfsmittel |
| US5129900B1 (en) * | 1990-07-24 | 1998-12-29 | Acromed Corp | Spinal column retaining method and apparatus |
| FR2668919B1 (fr) * | 1990-11-09 | 1993-01-22 | Landos Applic Orthopediques Fs | Broche intra-medullaire et son outil de prehension. |
-
1992
- 1992-11-13 FR FR9213694A patent/FR2697991B1/fr not_active Expired - Lifetime
-
1993
- 1993-11-12 JP JP51238294A patent/JP3737825B2/ja not_active Expired - Fee Related
- 1993-11-12 EP EP94902235A patent/EP0668750A4/en not_active Ceased
- 1993-11-12 CN CN93121427A patent/CN1092637A/zh active Pending
- 1993-11-12 FI FI952312A patent/FI952312A0/fi not_active Application Discontinuation
- 1993-11-12 AR AR93326571A patent/AR248078A1/es active
- 1993-11-12 CA CA002149322A patent/CA2149322A1/en not_active Abandoned
- 1993-11-12 AU AU56676/94A patent/AU682839B2/en not_active Ceased
- 1993-11-12 KR KR1019950701968A patent/KR950703899A/ko not_active Withdrawn
- 1993-11-12 WO PCT/US1993/010966 patent/WO1994010928A1/en not_active Ceased
- 1993-11-12 ZA ZA938465A patent/ZA938465B/xx unknown
-
1994
- 1994-05-04 TW TW083104029A patent/TW314459B/zh active
-
1995
- 1995-05-12 NO NO951900A patent/NO951900L/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JP3737825B2 (ja) | 2006-01-25 |
| KR950703899A (ko) | 1995-11-17 |
| EP0668750A4 (en) | 1996-04-10 |
| FR2697991A1 (fr) | 1994-05-20 |
| AU682839B2 (en) | 1997-10-23 |
| FR2697991B1 (fr) | 1995-02-03 |
| NO951900D0 (no) | 1995-05-12 |
| WO1994010928A1 (en) | 1994-05-26 |
| AU5667694A (en) | 1994-06-08 |
| FI952312A7 (fi) | 1995-05-12 |
| NO951900L (no) | 1995-06-16 |
| AR248078A1 (es) | 1995-06-30 |
| FI952312A0 (fi) | 1995-05-12 |
| ZA938465B (en) | 1994-09-15 |
| CN1092637A (zh) | 1994-09-28 |
| CA2149322A1 (en) | 1994-05-26 |
| JPH08505785A (ja) | 1996-06-25 |
| EP0668750A1 (en) | 1995-08-30 |
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