TW438802B - Exomethylene derivatives having antibacterial activity and their preparation process and pharmaceutical composition - Google Patents

Exomethylene derivatives having antibacterial activity and their preparation process and pharmaceutical composition Download PDF

Info

Publication number
TW438802B
TW438802B TW086118192A TW86118192A TW438802B TW 438802 B TW438802 B TW 438802B TW 086118192 A TW086118192 A TW 086118192A TW 86118192 A TW86118192 A TW 86118192A TW 438802 B TW438802 B TW 438802B
Authority
TW
Taiwan
Prior art keywords
methylene
nitro
hydroxyethyl
compound
oxy
Prior art date
Application number
TW086118192A
Other languages
English (en)
Chinese (zh)
Inventor
Tino Rossi
Daniele Andreotti
Giovanna Tedesco
Luca Tarsi
Emiliangelo Ratti
Original Assignee
Glaxo Wellcome Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Wellcome Spa filed Critical Glaxo Wellcome Spa
Application granted granted Critical
Publication of TW438802B publication Critical patent/TW438802B/zh

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D477/00Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Steroid Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
TW086118192A 1996-11-14 1997-12-03 Exomethylene derivatives having antibacterial activity and their preparation process and pharmaceutical composition TW438802B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9623684.9A GB9623684D0 (en) 1996-11-14 1996-11-14 Chemical compounds

Publications (1)

Publication Number Publication Date
TW438802B true TW438802B (en) 2001-06-07

Family

ID=10802915

Family Applications (1)

Application Number Title Priority Date Filing Date
TW086118192A TW438802B (en) 1996-11-14 1997-12-03 Exomethylene derivatives having antibacterial activity and their preparation process and pharmaceutical composition

Country Status (17)

Country Link
EP (1) EP0937078B1 (de)
JP (1) JP2001503765A (de)
KR (1) KR20000053258A (de)
AR (1) AR010585A1 (de)
AT (1) ATE232532T1 (de)
AU (1) AU727328B2 (de)
BR (1) BR9713982A (de)
CA (1) CA2271732A1 (de)
DE (1) DE69719054T2 (de)
ES (1) ES2191207T3 (de)
GB (1) GB9623684D0 (de)
HR (1) HRP970611A2 (de)
PE (1) PE14099A1 (de)
TR (1) TR199901705T2 (de)
TW (1) TW438802B (de)
WO (1) WO1998021210A1 (de)
ZA (1) ZA9710207B (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1055683A4 (de) 1998-02-17 2007-07-25 Nippon Kayaku Kk Neuartiges acetamid-derivat und verwendung desselben
US7601847B2 (en) 2004-10-26 2009-10-13 Wyeth Preparation and purification of 4-(indazol-3-yl)phenols

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CZ435990A3 (cs) * 1989-09-08 1999-11-17 Glaxo S.P.A. Kyselina 10-(1-hydroxyethyl)-11-oxo-1-azatricyklo/7,2,0,03,8/-undec-2en-2-karboxylová a její deriváty, způsob jejich výroby, použití pro výrobu farmaceutických prostředků a farmaceutické prostředky s jejich obsahem
AU636913B2 (en) * 1989-10-11 1993-05-13 Takeda Chemical Industries Ltd. Tricyclic carbapenem compounds
EP0507313A1 (de) * 1991-04-05 1992-10-07 Takeda Chemical Industries, Ltd. Polycyclische Carbapenem-Verbindungen, ihre Herstellung und Verwendung
JPH06166688A (ja) * 1992-10-02 1994-06-14 Takeda Chem Ind Ltd カルバペネム化合物、その製造法および抗菌組成物
JPH08245628A (ja) * 1995-01-12 1996-09-24 Takeda Chem Ind Ltd カルバペネム化合物、その製造法および剤

Also Published As

Publication number Publication date
WO1998021210A1 (en) 1998-05-22
AU5481598A (en) 1998-06-03
KR20000053258A (ko) 2000-08-25
TR199901705T2 (xx) 1999-12-21
GB9623684D0 (en) 1997-01-08
ZA9710207B (en) 1999-05-12
JP2001503765A (ja) 2001-03-21
EP0937078B1 (de) 2003-02-12
PE14099A1 (es) 1999-03-19
BR9713982A (pt) 2000-05-02
AU727328B2 (en) 2000-12-07
DE69719054T2 (de) 2003-11-27
CA2271732A1 (en) 1998-05-22
HRP970611A2 (en) 1998-10-31
ATE232532T1 (de) 2003-02-15
EP0937078A1 (de) 1999-08-25
DE69719054D1 (de) 2003-03-20
ES2191207T3 (es) 2003-09-01
AR010585A1 (es) 2000-06-28

Similar Documents

Publication Publication Date Title
US11028079B2 (en) Small molecule BET bromodomain inhibitors and uses thereof
JP2024023325A (ja) 補体因子b阻害剤及びその医薬組成物、製造方法並びに用途
CA2946459C (en) Imidazo[4,5-c]quinolin-2-one compounds and their use in treating cancer
JP2021107414A (ja) コロニー刺激因子−1受容体(csf−1r)阻害剤
US20230219986A1 (en) Novel aminopyrimidine egfr inhibitor
JP2016510758A (ja) β−セクレターゼ阻害剤としての過フッ素化シクロプロピル縮合1,3−オキサジン−2−アミン化合物、及び使用方法
CN105814049A (zh) 作为tnf活性调节剂的稠合三环咪唑衍生物
NZ517788A (en) Quinuclidine compounds and drugs containing the same as the active ingredient
EP0412798A2 (de) Substituierte Pyridine, ihre Herstellung, Zusammensetzungen und Anwendung gegen Dementia
KR20240026911A (ko) 골수성 세포 2 작용제 상에서 발현되는 유발 수용체로서의 헤테로고리 화합물 및 사용 방법
EP0402056A2 (de) Azabicyclische Verbindungen, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zubereitungen
CN114685490B (zh) 吡咯并吡啶类化合物及其应用
JP7649283B2 (ja) 新規複素環化合物
JP2021519316A (ja) Tlr2シグナル伝達の調節剤としての化合物
CN103249733A (zh) 用于治疗或预防轻度认知障碍的稠合的三唑
EP0323864A2 (de) Lipophile Oxadiazole
CN108779100B (zh) 3,4-二吡啶基吡唑类衍生物、其制备方法及其在医药上的应用
IL324276A (en) Egfr inhibitors for treating disease
TW438802B (en) Exomethylene derivatives having antibacterial activity and their preparation process and pharmaceutical composition
AU683679B2 (en) Substituted 6,11-ethano-6,11-dihydrobenzo(b) quinolizinium salts and compositions and methods of use thereof
FR2953837A1 (fr) Derives 9h-pyridino[3,4-b]indole disubstitues, leur preparation et leur utilisation therapeutique
FR2953838A1 (fr) Derives de 9h-beta-carboline (ou 9h-pyridino[3,4-b]indole) trisubstitues, leur preparation et leur utilisation therapeutique
US6531466B2 (en) Tricyclic carbapenem compounds
WO2025199438A1 (en) 7-azaindazole macrocycles and their use
WO2023007185A1 (en) Imidazole organic compounds and their use against inflammatory bowel disease