TWI762754B - 化合物在製備治療腦小血管病的藥物中的應用 - Google Patents

化合物在製備治療腦小血管病的藥物中的應用 Download PDF

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Publication number: TWI762754B
Authority: TW; Taiwan
Prior art keywords: cerebral; microbleeds; cerebral microbleeds; small vessel; drug
Prior art date: 2017-12-29

Application number

TW107147844A

Other languages

English (en)

Chinese (zh)

Other versions

TW201932115A (zh

Inventor

顏光美

銀巍

盛龍祥

陸秉政

黃奕俊

林穗珍

Original Assignee

中國大陸商廣州市賽普特醫藥科技股份有限公司

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2017-12-29

Filing date

2018-12-28

Publication date

2022-05-01

2018-12-28 Application filed by 中國大陸商廣州市賽普特醫藥科技股份有限公司 filed Critical 中國大陸商廣州市賽普特醫藥科技股份有限公司

2019-08-16 Publication of TW201932115A publication Critical patent/TW201932115A/zh

2022-05-01 Application granted granted Critical

2022-05-01 Publication of TWI762754B publication Critical patent/TWI762754B/zh

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- A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
- A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
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TW107147844A 2017-12-29 2018-12-28 化合物在製備治療腦小血管病的藥物中的應用 TWI762754B (zh)

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JP (1)	JP7097444B2 (fr)
KR (1)	KR102466251B1 (fr)
CN (1)	CN109985049B (fr)
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Publication number	Publication date
ES2951306T3 (es)	2023-10-19
EP3733190A1 (fr)	2020-11-04
CA3087115A1 (fr)	2019-07-04
IL275686A (en)	2020-08-31
EP3733190B1 (fr)	2023-07-12
US11911396B2 (en)	2024-02-27
EP3733190A4 (fr)	2021-09-29
IL275686B2 (en)	2024-06-01
IL275686B1 (en)	2024-02-01
PT3733190T (pt)	2023-07-27
TW201932115A (zh)	2019-08-16
JP2021507934A (ja)	2021-02-25
JP7097444B2 (ja)	2022-07-07
WO2019129179A1 (fr)	2019-07-04
AU2018396895B2 (en)	2021-05-27
CN109985049B (zh)	2022-02-22
CN109985049A (zh)	2019-07-09
CA3087115C (fr)	2023-04-11
KR102466251B1 (ko)	2022-11-10
US20200330483A1 (en)	2020-10-22
RU2752089C1 (ru)	2021-07-22
AU2018396895A1 (en)	2020-07-30
BR112020013318A2 (pt)	2020-12-01
KR20200104361A (ko)	2020-09-03

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JP2021138712A (ja)	2021-09-16	老化細胞を殺し、老化関連疾患および障害を処置するための方法と組成物
AU2016302254B2 (en)	2019-09-12	Compositions and methods for treating cancers associated with ETBR activation
JP7001599B2 (ja)	2022-01-19	急性骨髄性白血病の処置のためのダクチノマイシン組成物および方法
EP3220908B1 (fr)	2022-07-06	Compositions et méthodes de traitement de l'endométriose
WO2015152412A1 (fr)	2015-10-08	Promoteur d'administration de médicament contenant une substance permettant d'activer des récepteurs de lysophospholipides
WO2014137946A1 (fr)	2014-09-12	Procédés d'inhibition de l'activation de igf-1r ou de la signalisation en aval de celui-ci pour réduire la sénescence cellulaire induite par rayonnement
TWI762754B (zh)	2022-05-01	化合物在製備治療腦小血管病的藥物中的應用
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Wang et al.	2013	Minimally invasive procedures reduce perihematomal endothelin-1 levels and the permeability of the BBB in a rabbit model of intracerebral hematoma
WO2019103984A1 (fr)	2019-05-31	Compositions comprenant des inhibiteurs de fatp1, fatp3, fatp4, fatp5 et/ou fatp6 et utilisations associées
WO2020201444A1 (fr)	2020-10-08	Modification des indications de petites molécules pour des maladies et des troubles liés à la sénescence
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WO2017194031A1 (fr)	2017-11-16	Utilisation de l'inhibiteur du fonctionnement des protéines dapt dans la préparation d'un médicament pour le traitement de l'adénome
BR122024009541A2 (pt)	2024-06-18	Composição compreendendo nintedanib para tratar doenças oculares com neovascularização anormal
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