UA104126C2 - Профилактическая вакцина от туберкулеза - Google Patents

Профилактическая вакцина от туберкулеза

Info

Publication number
UA104126C2
UA104126C2 UAA200905336A UAA200905336A UA104126C2 UA 104126 C2 UA104126 C2 UA 104126C2 UA A200905336 A UAA200905336 A UA A200905336A UA A200905336 A UAA200905336 A UA A200905336A UA 104126 C2 UA104126 C2 UA 104126C2
Authority
UA
Ukraine
Prior art keywords
mtb
tuberculosis vaccine
virulent
prophylactic
strain
Prior art date
Application number
UAA200905336A
Other languages
English (en)
Ukrainian (uk)
Inventor
ИГЛЕСИАС Пере Хоан КАРДОНА
РЬЕРА Исабель АМАТ
Original Assignee
Арчивель Фарма, Сл
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Арчивель Фарма, Сл filed Critical Арчивель Фарма, Сл
Publication of UA104126C2 publication Critical patent/UA104126C2/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/04—Mycobacterium, e.g. Mycobacterium tuberculosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511—Organic adjuvants
    • A61K2039/55555—Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Communicable Diseases (AREA)
  • Pulmonology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oncology (AREA)
  • Dispersion Chemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

Изобретение относится к применению иммунотерапевтического средства, которое содержит фрагменты клеточной стенки комплекса(MTB-C), для получения лекарственного средства для профилактического лечения туберкулеза, в котором указанное средство получено с использованием способа, который включает культивирование вирулентного штамма МТВ-С на протяжении периода, который равняется или превышает три недели, с последующей гомогенизацией культуры клеток в присутствии неионного поверхностно-активного вещества.
UAA200905336A 2006-10-30 2007-10-17 Профилактическая вакцина от туберкулеза UA104126C2 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ES200602754A ES2307402B1 (es) 2006-10-30 2006-10-30 Vacuna profilactica contra la tuberculosis.
PCT/ES2007/000583 WO2008053055A1 (es) 2006-10-30 2007-10-17 Vacuna profiláctica contra la tuberculosis

Publications (1)

Publication Number Publication Date
UA104126C2 true UA104126C2 (ru) 2014-01-10

Family

ID=39343853

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA200905336A UA104126C2 (ru) 2006-10-30 2007-10-17 Профилактическая вакцина от туберкулеза

Country Status (19)

Country Link
US (1) US9289483B2 (ru)
EP (1) EP2090318B1 (ru)
JP (1) JP2010508254A (ru)
KR (1) KR20090087874A (ru)
CN (1) CN101600455B (ru)
AU (1) AU2007316091B2 (ru)
BR (1) BRPI0715297B8 (ru)
CA (1) CA2667965C (ru)
DK (1) DK2090318T3 (ru)
ES (2) ES2307402B1 (ru)
IL (1) IL198357A (ru)
MX (1) MX2009004258A (ru)
NZ (1) NZ576489A (ru)
PL (1) PL2090318T3 (ru)
PT (1) PT2090318E (ru)
RU (1) RU2526910C2 (ru)
UA (1) UA104126C2 (ru)
WO (1) WO2008053055A1 (ru)
ZA (1) ZA200902937B (ru)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2335177B1 (es) * 2008-09-19 2011-02-28 Archivel Farma, S.L. Agente inmunoterapeutico apropiado para la profilaxis primaria de la tuberculosis.
PE20120121A1 (es) 2008-12-08 2012-02-20 Gilead Connecticut Inc Derivados de imidazopirazina como inhibidores de syk
PL2716157T3 (pl) 2008-12-08 2017-06-30 Gilead Connecticut, Inc. Imidazopirazynowe inhibitory Syk
PL2661253T3 (pl) 2011-01-04 2017-08-31 Archivel Farma, Sl Preparat liposomowy odpowiedni do leczenia lub zapobiegania gruźlicy
EP2471511A1 (en) 2011-01-04 2012-07-04 Archivel Farma, SL Liposome formulation suitable for treating or preventing tuberculosis
DK2802345T3 (en) 2012-01-12 2018-04-30 Archivel Farma Sl MTB-C-VACCINE AGAINST ALLERGIC REACTIONS
US11339168B2 (en) 2019-02-22 2022-05-24 Kronos Bio, Inc. Crystalline forms of 6-(6-aminopyrazin-2-yl)-N-(4-(4-(oxetan-3-yl)piperazin-1-yl)phenyl)imidazo[1,2-a]pyrazin-8-amine as Syk inhibitors
EP4601620A1 (en) 2021-10-14 2025-08-20 Archivel Farma, S.l. Liposome formulations for treatment of active tuberculosis
WO2025191183A1 (en) 2024-03-15 2025-09-18 Archivel Farma S.L. Liposome formulations for the treatment of cancer

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6641814B1 (en) 1997-04-02 2003-11-04 Statens Serum Institut Nucleic acids fragments and polypeptide fragments derived from M. tuberculosis
RU2093046C1 (ru) * 1996-05-06 1997-10-20 Тихоокеанский институт биоорганической химии Дальневосточного отделения РАН Лечебно-профилактическая пищевая композиция "гербамарин"
US6284255B1 (en) 1996-08-29 2001-09-04 Genesis Research & Development Corporation Limited Compounds and methods for treatment and diagnosis of mycobacterial infections
WO1998039025A2 (en) * 1997-03-03 1998-09-11 Adcock Ingram Limited A composition comprising a carrier and a purified mycobacterial lipid cell-wall component and its use in the prevention, treatment and diagnosis of disease
US7037510B2 (en) * 1997-04-18 2006-05-02 Statens Serum Institut Hybrids of M. tuberculosis antigens
CA2346218A1 (en) 1998-10-08 2000-04-20 Statens Serum Institut Tuberculosis vaccine and diagnostic reagents based on antigens from the mycobacterium tuberculosis cell
RU2153354C1 (ru) * 1999-03-31 2000-07-27 Московский городской научно-практический центр борьбы с туберкулезом Вакцина против туберкулеза
US6420342B1 (en) * 2000-05-08 2002-07-16 N.V. Nutricia Nutritional preparation comprising ribose and medical use thereof
EP1351699A4 (en) * 2000-12-08 2006-07-05 Ying Dr Zhang METHOD FOR IMPROVED DIAGNOSIS AND TREATMENT OF MYCOBACTERIAL INFECTIONS
JP2005508613A (ja) 2001-07-04 2005-04-07 ヘルス プロテクション エージェンシー 潜伏中に発現されるマイコバクテリア抗原
CN1694725A (zh) * 2001-08-02 2005-11-09 纽约大学 肽在早期检测分枝杆菌疾病中的应用
WO2003018053A1 (en) 2001-08-22 2003-03-06 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. Vaccine against mycobacterial-induced diseases
GB2400560A (en) * 2002-01-29 2004-10-20 Rajiv Indravadan Modi Method of providing prophylaxis for tuberculosis in hiv positive individuals
CN1467221A (zh) * 2002-07-14 2004-01-14 虹 王 结核杆菌cfp-10、esat-6与cd40l融合疫苗的制备及应用
ES2231037B1 (es) * 2003-10-31 2005-12-16 Archivel Technologies, Sl Agente inmunoterapico util para el tratamiento combinado de la tuberculosis en asociacion con otros farmacos.
ES2335177B1 (es) * 2008-09-19 2011-02-28 Archivel Farma, S.L. Agente inmunoterapeutico apropiado para la profilaxis primaria de la tuberculosis.

Also Published As

Publication number Publication date
AU2007316091B2 (en) 2013-06-27
ZA200902937B (en) 2010-02-24
US20100068258A1 (en) 2010-03-18
BRPI0715297B1 (pt) 2019-01-29
ES2307402A1 (es) 2008-11-16
CN101600455B (zh) 2013-08-07
ES2307402B1 (es) 2009-09-30
EP2090318B1 (en) 2012-08-08
BRPI0715297B8 (pt) 2021-05-25
MX2009004258A (es) 2009-05-11
CN101600455A (zh) 2009-12-09
IL198357A (en) 2013-03-24
RU2526910C2 (ru) 2014-08-27
PL2090318T3 (pl) 2013-03-29
RU2009120522A (ru) 2013-01-20
BRPI0715297A2 (pt) 2015-02-03
CA2667965A1 (en) 2008-08-05
DK2090318T3 (da) 2012-11-19
JP2010508254A (ja) 2010-03-18
NZ576489A (en) 2012-02-24
HK1138786A1 (en) 2010-09-03
EP2090318A1 (en) 2009-08-19
CA2667965C (en) 2016-08-23
KR20090087874A (ko) 2009-08-18
WO2008053055A1 (es) 2008-05-08
US9289483B2 (en) 2016-03-22
ES2393007T3 (es) 2012-12-17
EP2090318A4 (en) 2010-01-27
IL198357A0 (en) 2011-08-01
AU2007316091A1 (en) 2008-05-08
PT2090318E (pt) 2012-11-14

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