UA108954C2 - Сполуки 2-(2,4,5-заміщеного аніліно)піримідину - Google Patents

Сполуки 2-(2,4,5-заміщеного аніліно)піримідину

Info

Publication number
UA108954C2
UA108954C2 UAA201403623A UAA201403623A UA108954C2 UA 108954 C2 UA108954 C2 UA 108954C2 UA A201403623 A UAA201403623 A UA A201403623A UA A201403623 A UAA201403623 A UA A201403623A UA 108954 C2 UA108954 C2 UA 108954C2
Authority
UA
Ukraine
Prior art keywords
compounds
salts
mutant
pyrimidine
useful
Prior art date
Application number
UAA201403623A
Other languages
English (en)
Ukrainian (uk)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed filed Critical
Publication of UA108954C2 publication Critical patent/UA108954C2/ru

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/10Spiro-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
UAA201403623A 2011-07-27 2012-07-25 Сполуки 2-(2,4,5-заміщеного аніліно)піримідину UA108954C2 (xx)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201161512061P 2011-07-27 2011-07-27

Publications (1)

Publication Number Publication Date
UA108954C2 true UA108954C2 (xx) 2015-06-25

Family

ID=53675818

Family Applications (3)

Application Number Title Priority Date Filing Date
UAA201403622A UA109736C2 (uk) 2011-07-27 2012-07-25 Поліморфна форма мезилатної солі 2-(2,4,5-заміщеного аніліно)піримідину (варіанти)
UAA201312949A UA106710C2 (uk) 2011-07-27 2012-07-25 Сполука 2-(2,4,5-заміщеного аніліно)піримідину та її застосування для лікування раку
UAA201403623A UA108954C2 (xx) 2011-07-27 2012-07-25 Сполуки 2-(2,4,5-заміщеного аніліно)піримідину

Family Applications Before (2)

Application Number Title Priority Date Filing Date
UAA201403622A UA109736C2 (uk) 2011-07-27 2012-07-25 Поліморфна форма мезилатної солі 2-(2,4,5-заміщеного аніліно)піримідину (варіанти)
UAA201312949A UA106710C2 (uk) 2011-07-27 2012-07-25 Сполука 2-(2,4,5-заміщеного аніліно)піримідину та її застосування для лікування раку

Country Status (2)

Country Link
AR (1) AR115019A2 (ru)
UA (3) UA109736C2 (ru)

Also Published As

Publication number Publication date
UA106710C2 (uk) 2014-09-25
UA109736C2 (uk) 2015-09-25
AR115019A2 (es) 2020-11-18

Similar Documents

Publication Publication Date Title
MX377900B (es) Derivados de 2-(2,4,5-anilino sustituido) pirimidina como moduladores de egfr util para el tratamiento del cancer.
EA201291220A1 (ru) Производные аминопиримидина в качестве модуляторов lrrk2
MX351305B (es) Antagonistas del receptor de mineralocorticoides.
ECSP13012611A (es) Derivados de pirazol-aminopirimidina como moduladores de la lrrk2
EA201500298A1 (ru) Алкоксипиразолы в качестве активаторов растворимой гуанилатциклазы
EA201590624A1 (ru) Циклические эфиры пиразол-4-ил-гетероциклил-карбоксамидных соединений и способы их применения
UA104489C2 (ru) Соединения для лечения дислипидемии и родственных болезней
TN2015000368A1 (en) Quinazoline inhibitors of activating mutant forms of epidermal growth factor receptor
PH12012502102A1 (en) Fused bicyclic kinase inhibitors
MX349556B (es) Derivados de aminopirimidina como moduladores de proteina cinasa 2 rica en unidades repetitivas de leucina (lrrk2).
MX2014006027A (es) Derivados de 2-fenilaminopirimidina como moduladores de proteina cinasa 2 rica en unidades repetitivas de leucina (lrrk2) para el tratamiento de la enfermedad de parkinson.
CY1118021T1 (el) Παραγωγο αζολιου
EA201370166A1 (ru) Содержащие диарилацетиленгидразид ингибиторы тирозинкиназы
MX387443B (es) Compuestos de heteroarilcarboxamida como inhibidores de ripk2
PH12020550228A1 (en) Epidermal growth factor receptor inhibitors
PH12014501943A1 (en) Novel compounds for the treatment of dyslipidemia and related diseases
UA108954C2 (xx) Сполуки 2-(2,4,5-заміщеного аніліно)піримідину
EA202092034A2 (ru) Производные 2-(2,4,5-замещенного анилино)пиримидина в качестве модуляторов egfr, полезных для лечения рака
NZ621471A (en) Kynurenine-3-monooxygenase inhibitors, pharmaceutical compositions, and methods of use thereof
TN2010000488A1 (en) Aminodihydrothiazine derivatives as bace inhibitors for the treatment of alzheimer's disease