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Medicines That Contain Protein Lipid Enzymes And Other Medicines
(AREA)
Peptides Or Proteins
(AREA)
Abstract
Винахід належить до пептиду або його фармацевтично прийнятної солі, які демонструють підвищену активність на GLP-1-рецепторі, порівняно з нативним глюкагоном, фармацевтичної композиції, що містить вказаний пептид або його фармацевтично прийнятну сіль, способу лікування та їх застосування.The invention relates to a peptide or its pharmaceutically acceptable salts, which exhibit increased activity on the GLP-1 receptor, in comparison with the native glucagon, of a pharmaceutical composition containing said peptide or its pharmaceutically acceptable salt, method of treatment and use thereof.
Glucagon analogs exhibiting agonist activity at the glusose-dependent insulinotropic peptide receptor (gip): pharmaceutical composition; and method to reduce weight gain or induce weight loss, particularly for the treatment of obesity.
Heterocyclic derivative compounds, glucagon receptor antagonists; pharmaceutical composition that includes it and its use in the treatment of diabetes and metabolic diseases. pct
Pharmaceutical composition for preventing or treating diabetes comprising a long-acting insulin conjugate and a long-acting insulinotropic peptide conjugate.
Compounds derived from benzyl sulfonamide, mogat-2 inhibitors; crystalline compound; pharmaceutical composition; and its use in the treatment of hypertriglyceridemia.
Compounds derived from aza adamantane, 11beta-hsd-1 inhibitors; pharmaceutical composition; method for prevention or treatment; and use to prevent or treat metabolic syndrome, type 2 diabetes as a result of obesity, insulin resistance, dyslipidemia, neuropathy, ischemia and infarction, among other diseases.