UA19039A - Спосіб одержаhhя еритропоетиhу людиhи - Google Patents
Спосіб одержаhhя еритропоетиhу людиhиInfo
- Publication number
- UA19039A UA19039A UA4203324A UA4203324A UA19039A UA 19039 A UA19039 A UA 19039A UA 4203324 A UA4203324 A UA 4203324A UA 4203324 A UA4203324 A UA 4203324A UA 19039 A UA19039 A UA 19039A
- Authority
- UA
- Ukraine
- Prior art keywords
- erythropoietin
- production
- provides
- dna
- constructs
- Prior art date
Links
- 102000003951 Erythropoietin Human genes 0.000 title abstract 3
- 108090000394 Erythropoietin Proteins 0.000 title abstract 3
- 229940105423 erythropoietin Drugs 0.000 title abstract 3
- OXCMYAYHXIHQOA-UHFFFAOYSA-N potassium;[2-butyl-5-chloro-3-[[4-[2-(1,2,4-triaza-3-azanidacyclopenta-1,4-dien-5-yl)phenyl]phenyl]methyl]imidazol-4-yl]methanol Chemical compound [K+].CCCCC1=NC(Cl)=C(CO)N1CC1=CC=C(C=2C(=CC=CC=2)C2=N[N-]N=N2)C=C1 OXCMYAYHXIHQOA-UHFFFAOYSA-N 0.000 title abstract 3
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- PXFBZOLANLWPMH-UHFFFAOYSA-N 16-Epiaffinine Natural products C1C(C2=CC=CC=C2N2)=C2C(=O)CC2C(=CC)CN(C)C1C2CO PXFBZOLANLWPMH-UHFFFAOYSA-N 0.000 abstract 1
- 101000987586 Homo sapiens Eosinophil peroxidase Proteins 0.000 abstract 1
- 101000920686 Homo sapiens Erythropoietin Proteins 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 238000005119 centrifugation Methods 0.000 abstract 1
- 239000007795 chemical reaction product Substances 0.000 abstract 1
- 238000004587 chromatography analysis Methods 0.000 abstract 1
- 238000010367 cloning Methods 0.000 abstract 1
- 210000003527 eukaryotic cell Anatomy 0.000 abstract 1
- 239000012634 fragment Substances 0.000 abstract 1
- 102000044890 human EPO Human genes 0.000 abstract 1
- 238000002955 isolation Methods 0.000 abstract 1
- 239000013612 plasmid Substances 0.000 abstract 1
- 238000001556 precipitation Methods 0.000 abstract 1
- 238000000746 purification Methods 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
Classifications
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Спосіб отримання людського еритропоетину передбачає культивування штамів еукаріотичних клітин, виділення і очищення цільового продукту шляхом концентрації, осадження, центрифугування і аффінної хроматографії. Попередньо конструюють рекомбінантні плазмідні ДНК, які забезпечують синтез еритропоетину, шляхом клонування кодуючого еритропоетин фрагмента ДНК.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US69325885A | 1985-01-22 | 1985-01-22 | |
| PCT/US1985/002405 WO1986003520A1 (en) | 1984-12-04 | 1985-12-03 | Method for the production of erythropoietin |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UA19039A true UA19039A (uk) | 1997-12-25 |
Family
ID=24783958
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UA4203324A UA19039A (uk) | 1985-01-22 | 1985-12-03 | Спосіб одержаhhя еритропоетиhу людиhи |
Country Status (4)
| Country | Link |
|---|---|
| DD (1) | DD279687A5 (uk) |
| MD (1) | MD95C2 (uk) |
| RU (1) | RU1801118C (uk) |
| UA (1) | UA19039A (uk) |
-
1985
- 1985-12-03 UA UA4203324A patent/UA19039A/uk unknown
-
1987
- 1987-09-09 RU SU874203324A patent/RU1801118C/ru active
- 1987-12-06 DD DD87310862A patent/DD279687A5/de unknown
-
1994
- 1994-02-09 MD MD94-0104A patent/MD95C2/ro active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| DD279687A5 (de) | 1990-06-13 |
| MD95B1 (ro) | 1994-11-30 |
| MD95C2 (ro) | 1995-03-31 |
| RU1801118C (ru) | 1993-03-07 |
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